Casp8ap2 (caspase 8 associated protein 2) - Rat Genome Database

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Gene: Casp8ap2 (caspase 8 associated protein 2) Mus musculus
Analyze
Symbol: Casp8ap2
Name: caspase 8 associated protein 2
RGD ID: 1314006
MGI Page MGI
Description: Enables cysteine-type endopeptidase activator activity involved in apoptotic process; identical protein binding activity; and protease binding activity. Acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors. Predicted to be located in cytoplasm and nucleus. Predicted to be active in PML body and mitochondrion. Is expressed in several structures, including brain ventricular layer; incisor; inner cell mass; renal calyx; and submandibular gland primordium. Orthologous to human CASP8AP2 (caspase 8 associated protein 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AA387232; CASP8-associated protein 2; D4Ertd659; D4Ertd659e; FL; FLASH; FLICE-associated huge protein; mKIAA1315
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39432,615,462 - 32,653,271 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl432,615,451 - 32,653,265 (+)EnsemblGRCm39 Ensembl
GRCm38432,615,470 - 32,653,271 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl432,615,451 - 32,653,265 (+)EnsemblGRCm38mm10GRCm38
MGSCv37432,702,448 - 32,740,240 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36432,944,126 - 32,981,873 (+)NCBIMGSCv36mm8
Celera432,362,733 - 32,400,576 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
4,4'-sulfonyldiphenol  (EXP)
8'-apo-beta,psi-caroten-8'-al  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (ISO)
C60 fullerene  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
cannabidiol  (ISO)
chloroprene  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
DDE  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dieldrin  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (ISO)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
gentamycin  (ISO)
glycitein  (ISO)
glycitin  (ISO)
hydrogen peroxide  (ISO)
ketoconazole  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
Mitotane  (ISO)
N-nitrosodiethylamine  (EXP)
oxaliplatin  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
propylparaben  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
succimer  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
topotecan  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
triptonide  (EXP)
tungsten  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
mitochondrion  (IBA,ISO)
nucleus  (ISO)
PML body  (IBA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Protection of Human Umbilical Vein Endothelial Cells against Oxidative Stress by MicroRNA-210. Li T, etal., Oxid Med Cell Longev. 2017;2017:3565613. doi: 10.1155/2017/3565613. Epub 2017 Mar 7.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Interactions of the mineralocorticoid receptor--within and without. Yang J and Fuller PJ, Mol Cell Endocrinol. 2012 Mar 24;350(2):196-205. doi: 10.1016/j.mce.2011.07.001. Epub 2011 Jul 18.
Additional References at PubMed
PMID:8889548   PMID:10235259   PMID:10349636   PMID:10537104   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11340079   PMID:11591653   PMID:11812828  
PMID:12466851   PMID:12477932   PMID:12520002   PMID:12654726   PMID:12904583   PMID:14610273   PMID:14621295   PMID:15592525   PMID:15883645   PMID:16141072   PMID:16141073   PMID:17245429  
PMID:18799693   PMID:19546234   PMID:21267068   PMID:21725362   PMID:21873635   PMID:23673342   PMID:25238250   PMID:26208142   PMID:27609454   PMID:31084574   PMID:32098917   PMID:32141129  
PMID:32325033  


Genomics

Comparative Map Data
Casp8ap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39432,615,462 - 32,653,271 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl432,615,451 - 32,653,265 (+)EnsemblGRCm39 Ensembl
GRCm38432,615,470 - 32,653,271 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl432,615,451 - 32,653,265 (+)EnsemblGRCm38mm10GRCm38
MGSCv37432,702,448 - 32,740,240 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36432,944,126 - 32,981,873 (+)NCBIMGSCv36mm8
Celera432,362,733 - 32,400,576 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.27NCBI
CASP8AP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38689,829,880 - 89,874,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl689,829,894 - 89,874,436 (+)EnsemblGRCh38hg38GRCh38
GRCh37690,539,599 - 90,584,155 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36690,596,379 - 90,640,876 (+)NCBINCBI36Build 36hg18NCBI36
Build 34690,596,378 - 90,640,875NCBI
Celera690,958,564 - 91,004,713 (+)NCBICelera
Cytogenetic Map6q15NCBI
HuRef687,756,992 - 87,803,539 (+)NCBIHuRef
CHM1_1690,637,186 - 90,681,833 (+)NCBICHM1_1
T2T-CHM13v2.0691,029,094 - 91,086,157 (+)NCBIT2T-CHM13v2.0
Casp8ap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8551,809,366 - 51,848,633 (+)NCBIGRCr8
mRatBN7.2547,014,501 - 47,052,276 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,014,667 - 47,052,275 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx549,156,788 - 49,194,344 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0550,755,948 - 50,793,505 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0550,701,113 - 50,738,716 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0547,853,699 - 47,891,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl547,853,818 - 47,891,668 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0552,451,775 - 52,489,186 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4548,920,175 - 48,958,139 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1548,928,473 - 49,096,830 (+)NCBI
Celera545,775,811 - 45,813,420 (+)NCBICelera
Cytogenetic Map5q21NCBI
Casp8ap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541116,535,646 - 16,568,139 (-)NCBIChiLan1.0ChiLan1.0
CASP8AP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25109,912,615 - 109,959,693 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16107,811,413 - 107,860,815 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0687,707,152 - 87,754,836 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1690,979,710 - 91,026,770 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl690,996,127 - 91,023,757 (+)Ensemblpanpan1.1panPan2
CASP8AP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11249,040,069 - 49,077,418 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1249,039,411 - 49,077,688 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1248,847,072 - 48,884,174 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01249,849,389 - 49,886,726 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1249,849,439 - 49,884,151 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11249,164,550 - 49,201,631 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01249,065,265 - 49,102,374 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01249,257,627 - 49,294,727 (+)NCBIUU_Cfam_GSD_1.0
Casp8ap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494684,022,998 - 84,049,994 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365102,420,920 - 2,447,986 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365102,420,924 - 2,447,634 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASP8AP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl157,835,145 - 57,862,473 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1157,834,251 - 57,864,837 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,689,689 - 64,811,590 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CASP8AP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11314,586,857 - 14,632,384 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1314,586,929 - 14,632,362 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040190,973,325 - 191,019,815 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Casp8ap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247994,302,738 - 4,353,211 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Casp8ap2
942 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:618
Count of miRNA genes:238
Interacting mature miRNAs:268
Transcripts:ENSMUST00000029950, ENSMUST00000108178, ENSMUST00000124278, ENSMUST00000127619, ENSMUST00000178925
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1302010Wta1_mweight adult 1 (mouse)Not determined4868324042683429Mouse
1558992Ses8_msalmonella enteritidis susceptibility 8 (mouse)Not determined4868324042683429Mouse
1301473Triglq1_mtriglyceride QTL 1 (mouse)Not determined4868324042683429Mouse
1302125Lxw1_mlupus BXSB x NZW 1 (mouse)Not determined4868324042683429Mouse
4141302Ssrq5_mstress response QTL 5 (mouse)Not determined868324042683430Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763283678Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
25440481Moaq1_mmodifier of alien QTL 1 (mouse)41950000046000000Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1302184Aaom1_mautoimmune aoritis in MRL mice 1 (mouse)Not determined42432229946332776Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
12903995Opfaq2_mopen field activity QTL 2 (mouse)43034341933824057Mouse

Markers in Region
AA536675  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38432,645,864 - 32,645,954UniSTSGRCm38
MGSCv37432,732,839 - 32,732,929UniSTSGRCm37
Celera432,393,171 - 32,393,261UniSTS
Cytogenetic Map4A5UniSTS
cM Map411.4UniSTS
Whitehead/MRC_RH4543.07UniSTS
UniSTS:234888  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38432,648,709 - 32,648,972UniSTSGRCm38
MGSCv37432,735,684 - 32,735,947UniSTSGRCm37
Celera432,396,016 - 32,396,279UniSTS
Cytogenetic Map4A5UniSTS
cM Map411.4UniSTS
AU015347  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38432,652,698 - 32,652,900UniSTSGRCm38
MGSCv37432,739,673 - 32,739,875UniSTSGRCm37
Celera432,400,006 - 32,400,207UniSTS
Cytogenetic Map4A5UniSTS
cM Map411.4UniSTS
Whitehead/MRC_RH4543.61UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001122978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006537949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006537950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF132726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL805973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL954737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE691553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY331503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA526466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF735200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000029950   ⟹   ENSMUSP00000029950
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,615,478 - 32,653,265 (+)Ensembl
GRCm38.p6 Ensembl432,615,478 - 32,653,265 (+)Ensembl
RefSeq Acc Id: ENSMUST00000108178   ⟹   ENSMUSP00000103813
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,624,084 - 32,653,265 (+)Ensembl
GRCm38.p6 Ensembl432,624,084 - 32,653,265 (+)Ensembl
RefSeq Acc Id: ENSMUST00000124278
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,615,451 - 32,631,810 (+)Ensembl
GRCm38.p6 Ensembl432,615,451 - 32,631,810 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127619
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,615,470 - 32,639,501 (+)Ensembl
GRCm38.p6 Ensembl432,615,470 - 32,639,501 (+)Ensembl
RefSeq Acc Id: ENSMUST00000178925   ⟹   ENSMUSP00000136016
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl432,615,473 - 32,653,265 (+)Ensembl
GRCm38.p6 Ensembl432,615,473 - 32,653,265 (+)Ensembl
RefSeq Acc Id: NM_001122978   ⟹   NP_001116450
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,615,470 - 32,653,271 (+)NCBI
GRCm38432,615,470 - 32,653,271 (+)NCBI
MGSCv37432,702,448 - 32,740,240 (+)RGD
Celera432,362,733 - 32,400,576 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_011997   ⟹   NP_036127
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,615,470 - 32,653,271 (+)NCBI
GRCm38432,615,470 - 32,653,271 (+)NCBI
MGSCv37432,702,448 - 32,740,240 (+)RGD
Celera432,362,733 - 32,400,576 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006537949   ⟹   XP_006538012
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,615,462 - 32,653,271 (+)NCBI
GRCm38432,615,499 - 32,653,271 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006537950   ⟹   XP_006538013
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39432,615,487 - 32,653,259 (+)NCBI
GRCm38432,615,499 - 32,653,265 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_036127   ⟸   NM_011997
- UniProtKB: B1AX74 (UniProtKB/Swiss-Prot),   Q9CSW2 (UniProtKB/Swiss-Prot),   Q9WUF3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001116450   ⟸   NM_001122978
- UniProtKB: B1AX74 (UniProtKB/Swiss-Prot),   Q9CSW2 (UniProtKB/Swiss-Prot),   Q9WUF3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006538012   ⟸   XM_006537949
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006538013   ⟸   XM_006537950
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000136016   ⟸   ENSMUST00000178925
RefSeq Acc Id: ENSMUSP00000029950   ⟸   ENSMUST00000029950
RefSeq Acc Id: ENSMUSP00000103813   ⟸   ENSMUST00000108178

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WUF3-F1-model_v2 AlphaFold Q9WUF3 1-1962 view protein structure

Promoters
RGD ID:6882964
Promoter ID:EPDNEW_M4933
Type:initiation region
Name:Casp8ap2_1
Description:Mus musculus caspase 8 associated protein 2 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4934  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38432,615,459 - 32,615,519EPDNEW
RGD ID:6882966
Promoter ID:EPDNEW_M4934
Type:multiple initiation site
Name:Casp8ap2_2
Description:Mus musculus caspase 8 associated protein 2 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4933  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38432,626,889 - 32,626,949EPDNEW
RGD ID:6835001
Promoter ID:MM_KWN:36967
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000108177,   NM_001122978,   NM_011997,   OTTMUST00000010996,   OTTMUST00000010997,   UC008SEW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36432,702,054 - 32,702,554 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1349399 AgrOrtholog
Ensembl Genes ENSMUSG00000028282 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000029950 ENTREZGENE
  ENSMUST00000029950.10 UniProtKB/Swiss-Prot
  ENSMUST00000108178.2 UniProtKB/TrEMBL
  ENSMUST00000178925 ENTREZGENE
  ENSMUST00000178925.8 UniProtKB/Swiss-Prot
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FLASH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gon4l/CASP8AP2_myb-like UniProtKB/Swiss-Prot
KEGG Report mmu:26885 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1349399 ENTREZGENE
NCBI Gene 26885 ENTREZGENE
PANTHER CASP8-ASSOCIATED PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15489 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Myb_DNA-binding_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Casp8ap2 PhenoGen
UniProt B1AX74 ENTREZGENE
  B1AX75_MOUSE UniProtKB/TrEMBL
  C8AP2_MOUSE UniProtKB/Swiss-Prot
  Q3TNP9_MOUSE UniProtKB/TrEMBL
  Q3U4R7_MOUSE UniProtKB/TrEMBL
  Q3UQU1_MOUSE UniProtKB/TrEMBL
  Q9CSW2 ENTREZGENE
  Q9WUF3 ENTREZGENE
UniProt Secondary B1AX74 UniProtKB/Swiss-Prot
  Q9CSW2 UniProtKB/Swiss-Prot