CASP8AP2 (caspase 8 associated protein 2) - Rat Genome Database

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Gene: CASP8AP2 (caspase 8 associated protein 2) Pan paniscus
Analyze
Symbol: CASP8AP2
Name: caspase 8 associated protein 2
RGD ID: 11761460
Description: ENCODES a protein that exhibits cysteine-type endopeptidase activator activity involved in apoptotic process (ortholog); identical protein binding (ortholog); protease binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); PARTICIPATES IN aldosterone signaling pathway; FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CASP8-associated protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25109,912,615 - 109,959,693 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16107,811,413 - 107,860,815 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0687,707,152 - 87,754,836 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1690,979,710 - 91,026,770 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl690,996,127 - 91,023,757 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
mitochondrion  (IEA)
nucleus  (IEA)
PML body  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CASP8AP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25109,912,615 - 109,959,693 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16107,811,413 - 107,860,815 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0687,707,152 - 87,754,836 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1690,979,710 - 91,026,770 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl690,996,127 - 91,023,757 (+)Ensemblpanpan1.1panPan2
CASP8AP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38689,829,880 - 89,874,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl689,829,894 - 89,874,436 (+)EnsemblGRCh38hg38GRCh38
GRCh37690,539,599 - 90,584,155 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36690,596,379 - 90,640,876 (+)NCBINCBI36Build 36hg18NCBI36
Build 34690,596,378 - 90,640,875NCBI
Celera690,958,564 - 91,004,713 (+)NCBICelera
Cytogenetic Map6q15NCBI
HuRef687,756,992 - 87,803,539 (+)NCBIHuRef
CHM1_1690,637,186 - 90,681,833 (+)NCBICHM1_1
T2T-CHM13v2.0691,029,094 - 91,086,157 (+)NCBIT2T-CHM13v2.0
Casp8ap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39432,615,462 - 32,653,271 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl432,615,451 - 32,653,265 (+)EnsemblGRCm39 Ensembl
GRCm38432,615,470 - 32,653,271 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl432,615,451 - 32,653,265 (+)EnsemblGRCm38mm10GRCm38
MGSCv37432,702,448 - 32,740,240 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36432,944,126 - 32,981,873 (+)NCBIMGSCv36mm8
Celera432,362,733 - 32,400,576 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.27NCBI
Casp8ap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8551,809,366 - 51,848,633 (+)NCBIGRCr8
mRatBN7.2547,014,501 - 47,052,276 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,014,667 - 47,052,275 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx549,156,788 - 49,194,344 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0550,755,948 - 50,793,505 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0550,701,113 - 50,738,716 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0547,853,699 - 47,891,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl547,853,818 - 47,891,668 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0552,451,775 - 52,489,186 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4548,920,175 - 48,958,139 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1548,928,473 - 49,096,830 (+)NCBI
Celera545,775,811 - 45,813,420 (+)NCBICelera
Cytogenetic Map5q21NCBI
Casp8ap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541116,535,646 - 16,568,139 (-)NCBIChiLan1.0ChiLan1.0
CASP8AP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11249,040,069 - 49,077,418 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1249,039,411 - 49,077,688 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1248,847,072 - 48,884,174 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01249,849,389 - 49,886,726 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1249,849,439 - 49,884,151 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11249,164,550 - 49,201,631 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01249,065,265 - 49,102,374 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01249,257,627 - 49,294,727 (+)NCBIUU_Cfam_GSD_1.0
Casp8ap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494684,022,998 - 84,049,994 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365102,420,920 - 2,447,986 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365102,420,924 - 2,447,634 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASP8AP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl157,835,145 - 57,862,473 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1157,834,251 - 57,864,837 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,689,689 - 64,811,590 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CASP8AP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11314,586,857 - 14,632,384 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1314,586,929 - 14,632,362 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040190,973,325 - 191,019,815 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Casp8ap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247994,302,738 - 4,353,211 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000064276   ⟹   ENSPPAP00000041350
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl690,996,127 - 91,021,533 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000064283   ⟹   ENSPPAP00000041357
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl691,002,010 - 91,023,757 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000064285   ⟹   ENSPPAP00000041359
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl691,002,010 - 91,021,569 (+)Ensembl
RefSeq Acc Id: XM_003822881   ⟹   XP_003822929
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25109,912,767 - 109,959,693 (+)NCBI
NHGRI_mPanPan16107,813,903 - 107,860,815 (+)NCBI
Mhudiblu_PPA_v0687,707,962 - 87,754,836 (+)NCBI
PanPan1.1690,979,710 - 91,026,770 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003822882   ⟹   XP_003822930
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25109,912,822 - 109,959,693 (+)NCBI
NHGRI_mPanPan16107,813,932 - 107,860,815 (+)NCBI
Mhudiblu_PPA_v0687,707,962 - 87,754,836 (+)NCBI
PanPan1.1690,979,722 - 91,026,770 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034962524   ⟹   XP_034818415
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25109,912,615 - 109,959,693 (+)NCBI
NHGRI_mPanPan16107,811,414 - 107,860,815 (+)NCBI
Mhudiblu_PPA_v0687,707,152 - 87,754,836 (+)NCBI
RefSeq Acc Id: XM_034962527   ⟹   XP_034818418
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25109,917,401 - 109,959,693 (+)NCBI
NHGRI_mPanPan16107,818,500 - 107,860,815 (+)NCBI
Mhudiblu_PPA_v0687,714,389 - 87,754,836 (+)NCBI
RefSeq Acc Id: XM_063604955   ⟹   XP_063461025
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25109,912,615 - 109,959,693 (+)NCBI
RefSeq Acc Id: XM_063604956   ⟹   XP_063461026
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25109,912,898 - 109,959,693 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003822929   ⟸   XM_003822881
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CHB1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003822930   ⟸   XM_003822882
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CHB1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034818415   ⟸   XM_034962524
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034818418   ⟸   XM_034962527
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CHB1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000041350   ⟸   ENSPPAT00000064276
RefSeq Acc Id: ENSPPAP00000041359   ⟸   ENSPPAT00000064285
RefSeq Acc Id: ENSPPAP00000041357   ⟸   ENSPPAT00000064283
RefSeq Acc Id: XP_063461025   ⟸   XM_063604955
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063461026   ⟸   XM_063604956
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043281 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000064276.1 UniProtKB/TrEMBL
  ENSPPAT00000064283.1 UniProtKB/TrEMBL
  ENSPPAT00000064285.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro FLASH UniProtKB/TrEMBL
  Gon4l/CASP8AP2_myb-like UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
NCBI Gene CASP8AP2 ENTREZGENE
PANTHER CASP8-ASSOCIATED PROTEIN 2 UniProtKB/TrEMBL
  PTHR15489 UniProtKB/TrEMBL
Pfam Myb_DNA-binding_7 UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A2R9CHB1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CHH2_PANPA UniProtKB/TrEMBL
  A0A2R9CR34_PANPA UniProtKB/TrEMBL