Ap2b1 (adaptor-related protein complex 2, beta 1 subunit) - Rat Genome Database

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Gene: Ap2b1 (adaptor-related protein complex 2, beta 1 subunit) Mus musculus
Analyze
Symbol: Ap2b1
Name: adaptor-related protein complex 2, beta 1 subunit
RGD ID: 737012
MGI Page MGI
Description: Predicted to enable clathrin binding activity. Involved in clathrin-dependent endocytosis and postsynaptic neurotransmitter receptor internalization. Acts upstream of or within circulatory system development and kidney development. Part of AP-2 adaptor complex. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human AP2B1 (adaptor related protein complex 2 subunit beta 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1300012O03Rik; adapter-related protein complex 2 beta subunit; adapter-related protein complex 2 subunit beta; adaptor protein complex AP-2 subunit beta; adaptor-related protein complex 2 subunit beta; AI788979; AP-2 complex subunit beta; AP105B; beta-2-adaptin; beta-adaptin; beta2-adaptin; clathrin assembly protein complex 2 beta large chain; plasma membrane adaptor HA2/AP2 adaptin beta subunit
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm12834   Gm19002   Gm3081   Gm7617  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391183,189,545 - 83,295,861 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1183,189,850 - 83,295,861 (+)EnsemblGRCm39 Ensembl
GRCm381183,298,719 - 83,405,035 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1183,299,024 - 83,405,035 (+)EnsemblGRCm38mm10GRCm38
MGSCv371183,116,199 - 83,218,537 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361183,118,892 - 83,221,230 (+)NCBIMGSCv36mm8
Celera1192,894,853 - 92,999,587 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1150.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1,4-dichlorobenzene  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
clozapine  (ISO)
cocaine  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (EXP)
dorsomorphin  (ISO)
ethanol  (EXP,ISO)
fluoxetine  (EXP)
folic acid  (EXP)
haloperidol  (ISO)
irinotecan  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
methylmercury chloride  (ISO)
methylphenidate  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
ozone  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
rac-lactic acid  (ISO)
resveratrol  (EXP)
SB 431542  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
urethane  (ISO)
valproic acid  (ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration. Rudinskiy N, etal., J Biol Chem. 2009 May 1;284(18):12447-58. doi: 10.1074/jbc.M804740200. Epub 2009 Feb 24.
9. Synaptic vesicle endocytosis. Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645.
Additional References at PubMed
PMID:8889548   PMID:9182572   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11591131   PMID:12086608   PMID:12383505   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14530274  
PMID:14610273   PMID:14681479   PMID:15489334   PMID:15761153   PMID:15782199   PMID:15941406   PMID:16141072   PMID:16141073   PMID:16512683   PMID:16602821   PMID:16959763   PMID:17290217  
PMID:17638910   PMID:17761170   PMID:18495661   PMID:18614564   PMID:18799693   PMID:20114047   PMID:20500056   PMID:21677750   PMID:21725061   PMID:21849563   PMID:21873635   PMID:22794259  
PMID:22922362   PMID:23676497   PMID:23719817   PMID:24217640   PMID:24319055   PMID:24448406   PMID:24457600   PMID:25211037   PMID:25807483   PMID:26025364   PMID:26680585   PMID:27002738  
PMID:27160897   PMID:27534441   PMID:28190767   PMID:28634551   PMID:28671696   PMID:28706196   PMID:29184887   PMID:29262337   PMID:30068389   PMID:30196744   PMID:30409884   PMID:30457570  
PMID:30562941   PMID:31138677   PMID:31235642   PMID:31291551   PMID:31671891   PMID:32325033   PMID:34321999   PMID:35449600   PMID:36293380  


Genomics

Comparative Map Data
Ap2b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391183,189,545 - 83,295,861 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1183,189,850 - 83,295,861 (+)EnsemblGRCm39 Ensembl
GRCm381183,298,719 - 83,405,035 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1183,299,024 - 83,405,035 (+)EnsemblGRCm38mm10GRCm38
MGSCv371183,116,199 - 83,218,537 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361183,118,892 - 83,221,230 (+)NCBIMGSCv36mm8
Celera1192,894,853 - 92,999,587 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1150.3NCBI
AP2B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381735,587,322 - 35,726,413 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1735,578,046 - 35,726,413 (+)EnsemblGRCh38hg38GRCh38
GRCh371733,914,341 - 34,053,432 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361730,938,395 - 31,077,549 (+)NCBINCBI36Build 36hg18NCBI36
Build 341730,938,405 - 31,077,541NCBI
Celera1730,824,398 - 30,963,574 (+)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1730,099,253 - 30,238,599 (+)NCBIHuRef
CHM1_11733,978,907 - 34,118,050 (+)NCBICHM1_1
T2T-CHM13v2.01736,535,193 - 36,674,326 (+)NCBIT2T-CHM13v2.0
Ap2b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81068,596,925 - 68,702,547 (+)NCBIGRCr8
mRatBN7.21068,099,397 - 68,205,023 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1068,099,547 - 68,205,013 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1072,723,218 - 72,825,030 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01072,228,605 - 72,330,413 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01067,692,649 - 67,794,463 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01070,516,462 - 70,621,973 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1070,520,206 - 70,621,977 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01071,035,406 - 71,067,828 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01071,068,935 - 71,083,997 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,386,233 - 71,488,000 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11071,399,684 - 71,502,555 (+)NCBI
Celera1067,045,800 - 67,146,677 (+)NCBICelera
Cytogenetic Map10q26NCBI
Ap2b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495548110,064,220 - 10,175,627 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495548110,061,021 - 10,175,070 (+)NCBIChiLan1.0ChiLan1.0
AP2B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21928,750,972 - 28,892,336 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11730,632,528 - 30,769,787 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01721,070,132 - 21,208,610 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11721,363,115 - 21,501,720 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1721,363,121 - 21,501,721 (-)Ensemblpanpan1.1panPan2
AP2B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1937,946,761 - 38,078,074 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl937,946,788 - 38,078,041 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha937,170,891 - 37,302,120 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0938,758,380 - 38,889,742 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl938,756,039 - 38,889,684 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1937,541,221 - 37,673,744 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0937,826,684 - 37,958,055 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0937,914,210 - 38,045,500 (-)NCBIUU_Cfam_GSD_1.0
Ap2b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560236,949,807 - 37,069,908 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649012,233 - 127,715 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364905,156 - 127,666 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AP2B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,800,972 - 39,932,643 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11239,803,105 - 39,940,801 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AP2B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11629,061,662 - 29,198,942 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1629,061,568 - 29,201,464 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666075774,355 - 913,998 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ap2b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248753,090,656 - 3,208,593 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248753,085,518 - 3,206,930 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ap2b1
2049 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2119
Count of miRNA genes:819
Interacting mature miRNAs:1084
Transcripts:ENSMUST00000018875, ENSMUST00000065692, ENSMUST00000132178, ENSMUST00000142680, ENSMUST00000176430, ENSMUST00000176523, ENSMUST00000176944
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117757387399377820Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse

Markers in Region
179H3-T7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,359,525 - 83,359,863UniSTSGRCm38
MGSCv371183,173,027 - 83,173,365UniSTSGRCm37
Celera1192,954,378 - 92,954,716UniSTS
Cytogenetic Map11B5UniSTS
cM Map11 UniSTS
D11Pas16  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,322,842 - 83,322,950UniSTSGRCm38
MGSCv371183,136,344 - 83,136,452UniSTSGRCm37
Celera1192,914,993 - 92,915,101UniSTS
Cytogenetic Map11B5UniSTS
cM Map11 UniSTS
D11Pas17  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,346,895 - 83,347,055UniSTSGRCm38
MGSCv371183,160,397 - 83,160,557UniSTSGRCm37
Celera1192,941,749 - 92,941,909UniSTS
Cytogenetic Map11B5UniSTS
cM Map11 UniSTS
AI788979  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,403,872 - 83,403,991UniSTSGRCm38
MGSCv371183,217,374 - 83,217,493UniSTSGRCm37
Celera1192,998,424 - 92,998,543UniSTS
Cytogenetic Map11B5UniSTS
Whitehead/MRC_RH111056.94UniSTS
Ap2b1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,402,650 - 83,402,984UniSTSGRCm38
MGSCv371183,216,152 - 83,216,486UniSTSGRCm37
Celera1192,997,202 - 92,997,536UniSTS
Cytogenetic Map11B5UniSTS
cM Map11 UniSTS
D11Bhm143  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,400,688 - 83,400,785UniSTSGRCm38
MGSCv371183,214,190 - 83,214,287UniSTSGRCm37
Celera1192,995,240 - 92,995,337UniSTS
Cytogenetic Map11B5UniSTS
cM Map1147.44UniSTS
CLAPB1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,389,731 - 83,390,720UniSTSGRCm38
MGSCv371183,203,233 - 83,204,222UniSTSGRCm37
Celera1192,984,273 - 92,985,262UniSTS
Cytogenetic Map11B5UniSTS
MARC_4629-4630:966894533:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,389,751 - 83,390,732UniSTSGRCm38
MGSCv371183,203,253 - 83,204,234UniSTSGRCm37
Celera1192,984,293 - 92,985,274UniSTS
Cytogenetic Map11B5UniSTS
AP2B1-1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384115,240,583 - 115,240,695UniSTSGRCm38
GRCm381183,335,545 - 83,336,396UniSTSGRCm38
MGSCv371183,149,047 - 83,149,898UniSTSGRCm37
MGSCv374114,913,188 - 114,913,300UniSTSGRCm37
Celera1192,927,689 - 92,928,541UniSTS
Celera4113,982,348 - 113,982,460UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map4D1UniSTS
Ap2b1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,402,653 - 83,402,984UniSTSGRCm38
MGSCv371183,216,155 - 83,216,486UniSTSGRCm37
Celera1192,997,205 - 92,997,536UniSTS
Cytogenetic Map11B5UniSTS
Ap2b1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B5UniSTS
Ap2b1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B5UniSTS
cM Map11 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001035854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_027915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006534258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017314772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEKQ02167340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL603711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC030349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC046772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LT629148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LT629151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000018875   ⟹   ENSMUSP00000018875
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1183,193,309 - 83,295,861 (+)Ensembl
GRCm38.p6 Ensembl1183,302,483 - 83,405,035 (+)Ensembl
RefSeq Acc Id: ENSMUST00000065692   ⟹   ENSMUSP00000070714
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1183,193,600 - 83,293,838 (+)Ensembl
GRCm38.p6 Ensembl1183,302,774 - 83,403,012 (+)Ensembl
RefSeq Acc Id: ENSMUST00000132178
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1183,193,529 - 83,235,406 (+)Ensembl
GRCm38.p6 Ensembl1183,302,703 - 83,344,580 (+)Ensembl
RefSeq Acc Id: ENSMUST00000142680   ⟹   ENSMUSP00000116562
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1183,193,778 - 83,207,341 (+)Ensembl
GRCm38.p6 Ensembl1183,302,952 - 83,316,515 (+)Ensembl
RefSeq Acc Id: ENSMUST00000176430   ⟹   ENSMUSP00000134779
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1183,193,560 - 83,289,423 (+)Ensembl
GRCm38.p6 Ensembl1183,302,734 - 83,398,597 (+)Ensembl
RefSeq Acc Id: ENSMUST00000176523   ⟹   ENSMUSP00000135445
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1183,199,064 - 83,293,470 (+)Ensembl
GRCm38.p6 Ensembl1183,308,238 - 83,402,644 (+)Ensembl
RefSeq Acc Id: ENSMUST00000176944   ⟹   ENSMUSP00000134798
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1183,189,850 - 83,223,884 (+)Ensembl
GRCm38.p6 Ensembl1183,299,024 - 83,333,058 (+)Ensembl
RefSeq Acc Id: NM_001035854   ⟹   NP_001030931
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391183,193,523 - 83,295,861 (+)NCBI
GRCm381183,302,697 - 83,405,035 (+)NCBI
MGSCv371183,116,199 - 83,218,537 (+)RGD
Celera1192,894,853 - 92,999,587 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_027915   ⟹   NP_082191
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391183,193,523 - 83,295,861 (+)NCBI
GRCm381183,302,697 - 83,405,035 (+)NCBI
MGSCv371183,116,199 - 83,218,537 (+)RGD
Celera1192,894,853 - 92,999,587 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006534258   ⟹   XP_006534321
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391183,189,795 - 83,294,992 (+)NCBI
GRCm381183,298,719 - 83,404,588 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017314772   ⟹   XP_017170261
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391183,189,545 - 83,294,992 (+)NCBI
GRCm381183,298,986 - 83,404,588 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156996   ⟹   XP_036012889
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391183,193,507 - 83,295,855 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001030931   ⟸   NM_001035854
- Peptide Label: isoform a
- UniProtKB: Q5SWR1 (UniProtKB/TrEMBL),   H3BIY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_082191   ⟸   NM_027915
- Peptide Label: isoform b
- UniProtKB: Q80XJ4 (UniProtKB/Swiss-Prot),   Q9DBG3 (UniProtKB/Swiss-Prot),   H3BIY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006534321   ⟸   XM_006534258
- Peptide Label: isoform X1
- UniProtKB: Q5SWR1 (UniProtKB/TrEMBL),   H3BIY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017170261   ⟸   XM_017314772
- Peptide Label: isoform X1
- UniProtKB: Q5SWR1 (UniProtKB/TrEMBL),   H3BIY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000070714   ⟸   ENSMUST00000065692
RefSeq Acc Id: ENSMUSP00000134798   ⟸   ENSMUST00000176944
RefSeq Acc Id: ENSMUSP00000134779   ⟸   ENSMUST00000176430
RefSeq Acc Id: ENSMUSP00000135445   ⟸   ENSMUST00000176523
RefSeq Acc Id: ENSMUSP00000116562   ⟸   ENSMUST00000142680
RefSeq Acc Id: ENSMUSP00000018875   ⟸   ENSMUST00000018875
RefSeq Acc Id: XP_036012889   ⟸   XM_036156996
- Peptide Label: isoform X1
- UniProtKB: Q5SWR1 (UniProtKB/TrEMBL),   H3BIY9 (UniProtKB/TrEMBL)
Protein Domains
Beta-adaptin appendage C-terminal subdomain   Clathrin adaptor alpha/beta/gamma-adaptin appendage   Clathrin/coatomer adaptor adaptin-like N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9DBG3-F1-model_v2 AlphaFold Q9DBG3 1-937 view protein structure

Promoters
RGD ID:6820392
Promoter ID:MM_KWN:8889
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000065692,   OTTMUST00000001780,   OTTMUST00000001781,   UC007KOR.1,   UC007KOS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361183,115,841 - 83,116,392 (+)MPROMDB
RGD ID:8675892
Promoter ID:EPDNEW_M15977
Type:initiation region
Name:Ap2b1_1
Description:Mus musculus adaptor-related protein complex 2, beta 1 subunit, transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15978  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381183,302,752 - 83,302,812EPDNEW
RGD ID:8675894
Promoter ID:EPDNEW_M15978
Type:single initiation site
Name:Ap2b1_2
Description:Mus musculus adaptor-related protein complex 2, beta 1 subunit, transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15977  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381183,305,539 - 83,305,599EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1919020 AgrOrtholog
Ensembl Genes ENSMUSG00000035152 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000018875 ENTREZGENE
  ENSMUST00000018875.13 UniProtKB/Swiss-Prot
  ENSMUST00000065692 ENTREZGENE
  ENSMUST00000065692.14 UniProtKB/Swiss-Prot
  ENSMUST00000142680.2 UniProtKB/TrEMBL
  ENSMUST00000176430.8 UniProtKB/TrEMBL
  ENSMUST00000176523 ENTREZGENE
  ENSMUST00000176523.2 UniProtKB/TrEMBL
  ENSMUST00000176944.8 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.310.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AP_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP_complex_bsu_1_2_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Armadillo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B-adaptin_app_sub_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Clathrin/coatomer_adapt-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Clathrin_a/b/g-adaptin_app_Ig UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Clathrin_app_Ig-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Clathrin_b-adaptin_app_Ig-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Coatomer/calthrin_app_sub_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBP_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:71770 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1919020 ENTREZGENE
NCBI Gene 71770 ENTREZGENE
PANTHER AP-2 COMPLEX SUBUNIT BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11134 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Adaptin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Alpha_adaptinC2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B2-adapt-app_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB AP2B1 RGD
PhenoGen Ap2b1 PhenoGen
PIRSF AP_complex_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Alpha_adaptinC2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B2-adapt-app_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49348 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55711 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AP2B1_MOUSE UniProtKB/Swiss-Prot
  H3BIY9 ENTREZGENE, UniProtKB/TrEMBL
  H3BJ06_MOUSE UniProtKB/TrEMBL
  H3BKM0_MOUSE UniProtKB/TrEMBL
  Q5SWR0_MOUSE UniProtKB/TrEMBL
  Q5SWR1 ENTREZGENE, UniProtKB/TrEMBL
  Q80XJ4 ENTREZGENE
  Q9DBG3 ENTREZGENE
UniProt Secondary Q80XJ4 UniProtKB/Swiss-Prot