Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FAM3C mRNA | CTD | PMID:22079256 | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | FAM3C (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to FAM3C protein | CTD | PMID:32991956 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of FAM3C mRNA | CTD | PMID:17555576 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM3C mRNA | CTD | PMID:17101203 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FAM3C mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM3C mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM3C mRNA | CTD | PMID:26290441 | 4,4'-sulfonyldiphenol | decreases expression | EXP | | 6480464 | bisphenol S results in decreased expression of FAM3C mRNA | CTD | PMID:33297965 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of FAM3C mRNA | CTD | PMID:28973697 | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of FAM3C mRNA | CTD | PMID:28973697 | 9-cis-retinoic acid | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Alitretinoin results in increased expression of FAM3C mRNA | CTD | PMID:15982314 | acetamide | increases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | acetamide results in increased expression of FAM3C mRNA | CTD | PMID:31881176 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of FAM3C mRNA | CTD | PMID:30807115 | all-trans-4-oxoretinoic acid | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | 4-oxoretinoic acid results in increased expression of FAM3C mRNA | CTD | PMID:15982314 | all-trans-retinoic acid | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Tretinoin metabolite results in increased expression of FAM3C mRNA and Tretinoin results in increased expression of FAM3C mRNA | CTD | PMID:15982314 and PMID:21934132 | all-trans-retinoic acid | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of FAM3C mRNA | CTD | PMID:33167477 | ammonium chloride | affects expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of FAM3C mRNA | CTD | PMID:16483693 | aristolochic acid A | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of FAM3C mRNA | CTD | PMID:33212167 | avobenzone | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | avobenzone results in increased expression of FAM3C mRNA | CTD | PMID:31016361 | benzo[a]pyrene | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of FAM3C mRNA | CTD | PMID:20064835 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of FAM3C intron | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | FAM3C (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of FAM3C promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of FAM3C mRNA | CTD | PMID:22228805 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FAM3C mRNA | CTD | PMID:26063408 and PMID:33221593 | bisphenol A | decreases methylation | ISO | FAM3C (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of FAM3C gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of FAM3C mRNA and bisphenol A results in decreased expression of FAM3C protein | CTD | PMID:29275510 and PMID:37567409 | bisphenol A | decreases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of FAM3C mRNA | CTD | PMID:25181051 more ... | cadmium dichloride | decreases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of FAM3C mRNA | CTD | PMID:33453195 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of FAM3C mRNA | CTD | PMID:37019170 | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of FAM3C mRNA | CTD | PMID:28472532 | cisplatin | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of FAM3C mRNA | CTD | PMID:27594783 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of FAM3C mRNA | CTD | PMID:21266533 | diuron | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Diuron results in decreased expression of FAM3C mRNA | CTD | PMID:35967413 | dorsomorphin | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM3C mRNA | CTD | PMID:27188386 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of FAM3C mRNA | CTD | PMID:35436446 | fenthion | decreases expression | EXP | | 6480464 | Fenthion results in decreased expression of FAM3C mRNA | CTD | PMID:34813904 | fipronil | decreases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | fipronil results in decreased expression of FAM3C mRNA | CTD | PMID:34044035 | flutamide | increases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of FAM3C mRNA | CTD | PMID:24136188 | glafenine | increases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | Glafenine results in increased expression of FAM3C mRNA | CTD | PMID:24136188 | glyphosate | affects methylation | ISO | Fam3c (Rattus norvegicus) | 6480464 | Glyphosate affects the methylation of FAM3C gene | CTD | PMID:35440735 | irinotecan | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Irinotecan analog results in decreased expression of FAM3C mRNA | CTD | PMID:18927307 | isotretinoin | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Isotretinoin results in increased expression of FAM3C mRNA | CTD | PMID:15982314 | isotretinoin | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of FAM3C mRNA | CTD | PMID:20436886 | ivermectin | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of FAM3C protein | CTD | PMID:32959892 | lead(0) | affects expression | ISO | FAM3C (Homo sapiens) | 6480464 | Lead affects the expression of FAM3C mRNA | CTD | PMID:28903495 | methidathion | decreases expression | EXP | | 6480464 | methidathion results in decreased expression of FAM3C mRNA | CTD | PMID:34813904 | methylmercury chloride | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of FAM3C mRNA | CTD | PMID:26272509 | methylparaben | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | methylparaben results in decreased expression of FAM3C mRNA | CTD | PMID:31745603 | N-nitrosodiethylamine | decreases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | Diethylnitrosamine results in decreased expression of FAM3C mRNA | CTD | PMID:20360939 | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of FAM3C mRNA | CTD | PMID:24535843 | N-nitrosodiethylamine | increases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | Diethylnitrosamine results in increased expression of FAM3C mRNA | CTD | PMID:19638242 | nickel sulfate | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of FAM3C mRNA | CTD | PMID:22714537 | paclitaxel | affects response to substance | ISO | FAM3C (Homo sapiens) | 6480464 | FAM3C protein affects the susceptibility to Paclitaxel | CTD | PMID:16217747 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of FAM3C mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of FAM3C mRNA | CTD | PMID:29067470 | potassium chromate | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of FAM3C mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FAM3C mRNA | CTD | PMID:22079256 | quercitrin | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | quercitrin results in increased expression of FAM3C mRNA | CTD | PMID:25193878 | SB 431542 | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | sodium arsenite | affects methylation | ISO | FAM3C (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of FAM3C gene | CTD | PMID:28589171 | sodium dichromate | increases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | sodium bichromate results in increased expression of FAM3C mRNA | CTD | PMID:25993096 | thapsigargin | increases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | Thapsigargin results in increased expression of FAM3C protein | CTD | PMID:35544339 | thimerosal | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Thimerosal results in increased expression of FAM3C mRNA | CTD | PMID:27188386 | thioacetamide | increases expression | ISO | Fam3c (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of FAM3C mRNA | CTD | PMID:23411599 | trichostatin A | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | trichostatin A results in increased expression of FAM3C mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM3C mRNA | CTD | PMID:27188386 | tunicamycin | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of FAM3C mRNA | CTD | PMID:22378314 | uranium atom | affects expression | ISO | FAM3C (Homo sapiens) | 6480464 | Uranium affects the expression of FAM3C mRNA | CTD | PMID:15672453 | urethane | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Urethane results in increased expression of FAM3C mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of FAM3C mRNA | CTD | PMID:23179753 more ... | valproic acid | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of FAM3C mRNA | CTD | PMID:23179753 more ... | valproic acid | decreases methylation | ISO | FAM3C (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of FAM3C gene | CTD | PMID:29154799 | vincaleukoblastine | affects response to substance | ISO | FAM3C (Homo sapiens) | 6480464 | FAM3C protein affects the susceptibility to Vinblastine | CTD | PMID:16217747 | vorinostat | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | vorinostat results in decreased expression of FAM3C mRNA | CTD | PMID:27188386 | |