(1->4)-beta-D-glucan multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PKM mRNA CTD PMID:36331819 (R)-adrenaline multiple interactions ISO Pkm (Rattus norvegicus) 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PKM protein CTD PMID:19464573 (R)-adrenaline increases expression EXP 6480464 Epinephrine results in increased expression of PKM protein CTD PMID:36423730 (R)-adrenaline increases expression ISO PKM (Homo sapiens) 6480464 Epinephrine results in increased expression of PKM protein CTD PMID:36423730 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO PKM (Homo sapiens) 6480464 o and p'-DDT results in increased expression of PKM mRNA CTD PMID:19371625 1,2,4-trimethylbenzene decreases expression ISO Pkm (Rattus norvegicus) 6480464 pseudocumene results in decreased expression of PKM protein CTD PMID:17337753 1,4-benzoquinone multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [quinone results in increased degradation of PKM protein] more ... CTD PMID:25437431 1,4-benzoquinone increases expression ISO PKM (Homo sapiens) 6480464 quinone results in increased expression of PKM protein CTD PMID:30448556 1,4-benzoquinone multiple interactions ISO PKM (Homo sapiens) 6480464 [HIF1A protein co-treated with quinone] results in increased expression of PKM protein CTD PMID:30448556 1-chloro-2,4-dinitrobenzene increases metabolic processing ISO PKM (Homo sapiens) 6480464 Dinitrochlorobenzene results in increased metabolism of PKM protein CTD PMID:29267982 14-Deoxy-11,12-didehydroandrographolide decreases expression ISO PKM (Homo sapiens) 6480464 14-deoxy-11 and 12-didehydroandrographolide results in decreased expression of PKM mRNA CTD PMID:22101062 17alpha-ethynylestradiol increases expression ISO Pkm (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of PKM mRNA CTD PMID:12075121 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of PKM mRNA CTD PMID:19484750 17beta-estradiol decreases expression ISO Pkm (Rattus norvegicus) 6480464 Estradiol results in decreased expression of PKM mRNA CTD PMID:32145629 17beta-estradiol multiple interactions ISO PKM (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased phosphorylation of and affects the localization of PKM protein] more ... CTD PMID:32078667 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO PKM (Homo sapiens) 6480464 Metribolone promotes the reaction [NDRG1 protein binds to PKM protein] CTD PMID:17220478 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO PKM (Homo sapiens) 6480464 2 more ... CTD PMID:30821169 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO PKM (Homo sapiens) 6480464 2 more ... CTD PMID:30821169 2,3',4,4',5-Pentachlorobiphenyl multiple interactions ISO PKM (Homo sapiens) 6480464 2 more ... CTD PMID:30821169 and PMID:31251971 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO PKM (Homo sapiens) 6480464 2 more ... CTD PMID:30821169 and PMID:31251971 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Pkm (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PKM protein CTD PMID:16548065 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Pkm (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of PKM mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PKM mRNA more ... CTD PMID:19770486 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PKM mRNA CTD PMID:21570461 and PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO PKM (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PKM mRNA CTD PMID:23152189 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO PKM (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PKM mRNA] and alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PKM mRNA] CTD PMID:23152189 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO Pkm (Rattus norvegicus) 6480464 2 more ... CTD PMID:19954255 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression ISO Pkm (Rattus norvegicus) 6480464 2 more ... CTD PMID:19954255 2,4-dinitrotoluene affects expression ISO Pkm (Rattus norvegicus) 6480464 2 and 4-dinitrotoluene affects the expression of PKM mRNA CTD PMID:21346803 2,5-hexanedione increases expression ISO Pkm (Rattus norvegicus) 6480464 2 and 5-hexanedione results in increased expression of PKM protein CTD PMID:19033394 2-acetamidofluorene increases expression ISO Pkm (Rattus norvegicus) 6480464 2-Acetylaminofluorene results in increased expression of PKM mRNA and 2-Acetylaminofluorene results in increased expression of PKM protein CTD PMID:17538966 2-deoxy-D-glucose multiple interactions ISO PKM (Homo sapiens) 6480464 Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of PKM protein] CTD PMID:35945655 2-hydroxypropanoic acid increases abundance ISO PKM (Homo sapiens) 6480464 PKM protein results in increased abundance of Lactic Acid CTD PMID:22574221 2-hydroxypropanoic acid increases expression ISO PKM (Homo sapiens) 6480464 Lactic Acid results in increased expression of PKM protein CTD PMID:36336208 2-hydroxypropanoic acid multiple interactions ISO PKM (Homo sapiens) 6480464 Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] more ... CTD PMID:36336208 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO PKM (Homo sapiens) 6480464 3 more ... CTD PMID:28284859 and PMID:30821169 3,3',4,4',5-pentachlorobiphenyl increases expression ISO PKM (Homo sapiens) 6480464 3 more ... CTD PMID:28284859 and PMID:30821169 3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expression EXP 6480464 3 more ... CTD PMID:27052460 3,5-diethoxycarbonyl-1,4-dihydrocollidine multiple interactions EXP 6480464 GW 3965 inhibits the reaction [3 more ... CTD PMID:27052460 3-chloropropane-1,2-diol increases expression ISO Pkm (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased expression of PKM protein CTD PMID:26072098 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO PKM (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PKM mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PKM mRNA CTD PMID:28628672 3-methyladenine multiple interactions ISO PKM (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] and 3-methyladenine inhibits the reaction [Potassium Dichromate results in increased expression of PKM protein] CTD PMID:32569804 more ... 3-phenylprop-2-enal increases metabolic processing ISO PKM (Homo sapiens) 6480464 cinnamaldehyde results in increased metabolism of PKM protein CTD PMID:29267982 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of PKM mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol increases expression ISO PKM (Homo sapiens) 6480464 bisphenol S results in increased expression of PKM protein CTD PMID:34186270 4-chlorobiphenyl increases expression ISO PKM (Homo sapiens) 6480464 4-chlorobiphenyl metabolite results in increased expression of PKM mRNA CTD PMID:25417049 4-hydroxynon-2-enal multiple interactions ISO PKM (Homo sapiens) 6480464 4-hydroxy-2-nonenal binds to and results in decreased activity of PKM protein and 4-hydroxy-2-nonenal promotes the reaction [PKM protein binds to PKM protein] CTD PMID:27978618 4-hydroxynon-2-enal affects binding ISO PKM (Homo sapiens) 6480464 4-hydroxy-2-nonenal analog binds to PKM protein CTD PMID:27978618 4-phenylbutyric acid multiple interactions ISO PKM (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of PKM protein] CTD PMID:32569804 and PMID:36473502 5-aza-2'-deoxycytidine affects methylation ISO PKM (Homo sapiens) 6480464 Decitabine affects the methylation of PKM gene CTD PMID:17630775 5-azacytidine increases expression ISO PKM (Homo sapiens) 6480464 Azacitidine results in increased expression of PKM mRNA CTD PMID:20823114 5-Hydroxyflavone multiple interactions ISO PKM (Homo sapiens) 6480464 5-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 6-Hydroxyflavone multiple interactions ISO PKM (Homo sapiens) 6480464 6-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 7-hydroxyflavone multiple interactions ISO PKM (Homo sapiens) 6480464 7-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 7H-xanthine multiple interactions ISO Pkm (Rattus norvegicus) 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PKM protein and [Xanthine co-treated with XDH protein] results in decreased expression of PKM protein CTD PMID:19464573 9-cis-retinoic acid decreases expression ISO PKM (Homo sapiens) 6480464 Alitretinoin results in decreased expression of PKM protein CTD PMID:28886987 9H-xanthine multiple interactions ISO Pkm (Rattus norvegicus) 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PKM protein and [Xanthine co-treated with XDH protein] results in decreased expression of PKM protein CTD PMID:19464573 acetamide increases expression ISO Pkm (Rattus norvegicus) 6480464 acetamide results in increased expression of PKM mRNA CTD PMID:31881176 acrolein multiple interactions ISO PKM (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PKM mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of PKM mRNA CTD PMID:32699268 acrylamide increases expression ISO Pkm (Rattus norvegicus) 6480464 Acrylamide results in increased expression of PKM mRNA CTD PMID:28959563 aflatoxin B1 decreases expression ISO PKM (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of PKM mRNA CTD PMID:22100608 aflatoxin B1 increases expression ISO PKM (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of PKM mRNA CTD PMID:27153756 aflatoxin B1 increases methylation ISO PKM (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of PKM gene CTD PMID:27153756 aldehydo-D-glucose multiple interactions ISO PKM (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [Glucose promotes the reaction [Estradiol results in increased phosphorylation of PKM protein]] more ... CTD PMID:23086999 more ... aldehydo-D-glucose increases uptake ISO PKM (Homo sapiens) 6480464 PKM protein results in increased uptake of Glucose CTD PMID:22574221 all-trans-retinoic acid increases expression ISO PKM (Homo sapiens) 6480464 Tretinoin results in increased expression of PKM mRNA CTD PMID:15894607 more ... all-trans-retinoic acid decreases expression ISO PKM (Homo sapiens) 6480464 Tretinoin results in decreased expression of PKM protein CTD PMID:28886987 all-trans-retinoic acid multiple interactions ISO PKM (Homo sapiens) 6480464 [Tretinoin co-treated with arsenic trioxide] results in increased expression of PKM mRNA CTD PMID:15894607 alpha-D-galactose multiple interactions ISO PKM (Homo sapiens) 6480464 Galactose affects the reaction [Fusaric Acid results in increased expression of PKM mRNA] CTD PMID:31654802 alpha-naphthoflavone multiple interactions ISO PKM (Homo sapiens) 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PKM mRNA] CTD PMID:23152189 alpha-pinene multiple interactions ISO PKM (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PKM mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of PKM mRNA CTD PMID:32699268 alpha-Zearalanol decreases expression ISO Pkm (Rattus norvegicus) 6480464 Zeranol results in decreased expression of PKM mRNA CTD PMID:35163327 ammonium chloride affects expression ISO Pkm (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of PKM mRNA CTD PMID:16483693 ampicillin increases expression ISO PKM (Homo sapiens) 6480464 Ampicillin results in increased expression of PKM mRNA CTD PMID:21632981 apigenin multiple interactions ISO PKM (Homo sapiens) 6480464 Apigenin inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 aristolochic acid A increases expression ISO PKM (Homo sapiens) 6480464 aristolochic acid I results in increased expression of PKM protein CTD PMID:33212167 arsane affects binding ISO PKM (Homo sapiens) 6480464 Arsenic binds to PKM protein CTD PMID:17499915 arsenic atom affects binding ISO PKM (Homo sapiens) 6480464 Arsenic binds to PKM protein CTD PMID:17499915 arsenite(3-) multiple interactions ISO PKM (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to PKM protein] CTD PMID:32406909 arsenous acid multiple interactions ISO PKM (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PKM mRNA more ... CTD PMID:15894607 and PMID:31003765 arsenous acid decreases expression ISO PKM (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of PKM mRNA and Arsenic Trioxide results in decreased expression of PKM protein CTD PMID:31003765 arsenous acid increases expression ISO PKM (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PKM protein CTD PMID:25419056 atorvastatin calcium increases expression ISO Pkm (Rattus norvegicus) 6480464 Atorvastatin results in increased expression of PKM mRNA CTD PMID:27377005 atrazine increases expression ISO PKM (Homo sapiens) 6480464 Atrazine results in increased expression of PKM mRNA CTD PMID:22378314 baicalein increases activity ISO PKM (Homo sapiens) 6480464 baicalein results in increased activity of PKM protein CTD PMID:25388478 baicalin increases activity ISO PKM (Homo sapiens) 6480464 baicalin results in increased activity of PKM protein CTD PMID:25388478 Bardoxolone methyl decreases expression ISO PKM (Homo sapiens) 6480464 bardoxolone methyl results in decreased expression of PKM protein CTD PMID:35929395 benzo[a]pyrene increases mutagenesis ISO PKM (Homo sapiens) 6480464 Benzo(a)pyrene results in increased mutagenesis of PKM gene CTD PMID:25435355 benzo[a]pyrene increases expression ISO PKM (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of PKM mRNA CTD PMID:32234424 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of PKM mRNA CTD PMID:19770486 and PMID:32417428 benzo[a]pyrene diol epoxide I decreases expression ISO PKM (Homo sapiens) 6480464 7 more ... CTD PMID:20018196 bifenthrin increases expression EXP 6480464 bifenthrin results in increased expression of PKM mRNA CTD PMID:26071804 bis(2-chloroethyl) sulfide affects expression ISO Pkm (Rattus norvegicus) 6480464 Mustard Gas affects the expression of PKM mRNA CTD PMID:15651846 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of PKM mRNA CTD PMID:19850644 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of PKM mRNA CTD PMID:30284816 bis(2-ethylhexyl) phthalate increases expression ISO PKM (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of PKM mRNA CTD PMID:31163220 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of PKM mRNA] CTD PMID:19850644 bisphenol A increases expression ISO PKM (Homo sapiens) 6480464 bisphenol A results in increased expression of PKM mRNA and bisphenol A results in increased expression of PKM protein CTD PMID:19371625 more ... bisphenol A decreases expression ISO PKM (Homo sapiens) 6480464 bisphenol A results in decreased expression of PKM protein CTD PMID:34186270 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PKM protein CTD PMID:35999755 bisphenol A affects expression ISO Pkm (Rattus norvegicus) 6480464 bisphenol A affects the expression of PKM mRNA CTD PMID:32145629 bisphenol A affects expression ISO PKM (Homo sapiens) 6480464 bisphenol A affects the expression of PKM mRNA CTD PMID:30903817 bisphenol A multiple interactions ISO PKM (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PKM mRNA CTD PMID:28628672 bisphenol A increases expression ISO Pkm (Rattus norvegicus) 6480464 bisphenol A results in increased expression of PKM mRNA CTD PMID:12075121 and PMID:25181051 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PKM mRNA CTD PMID:26063408 bisphenol A multiple interactions ISO Pkm (Rattus norvegicus) 6480464 [Fructose co-treated with bisphenol A] results in decreased expression of PKM protein CTD PMID:26930160 Bisphenol B increases expression ISO PKM (Homo sapiens) 6480464 bisphenol B results in increased expression of PKM protein CTD PMID:34186270 bisphenol F multiple interactions ISO PKM (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PKM mRNA CTD PMID:28628672 bisphenol F increases expression ISO PKM (Homo sapiens) 6480464 bisphenol F results in increased expression of PKM protein CTD PMID:34186270 bisphenol F multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol F results in increased expression of PKM mRNA] more ... CTD PMID:34147605 bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of PKM mRNA and bisphenol F results in increased expression of PKM protein CTD PMID:34147605 bruceine D multiple interactions ISO PKM (Homo sapiens) 6480464 bruceine D affects the reaction [Oxygen deficiency affects the expression of PKM protein] and CTNNBIP1 protein affects the reaction [bruceine D affects the reaction [Oxygen deficiency affects the expression of PKM protein]] CTD PMID:34900531 C.I. Natural Red 20 multiple interactions EXP 6480464 shikonin inhibits the reaction [[Tobacco Smoke Pollution results in increased abundance of Particulate Matter] which results in increased expression of PKM protein] CTD PMID:35787437 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM mRNA and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein CTD PMID:32917723 and PMID:34481905 cadmium atom multiple interactions ISO PKM (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] more ... CTD PMID:34481905 and PMID:36336208 cadmium dichloride multiple interactions ISO PKM (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] more ... CTD PMID:24980261 more ... cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM mRNA and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein CTD PMID:32917723 and PMID:34481905 cadmium dichloride increases expression ISO Pkm (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of PKM mRNA CTD PMID:25993096 cadmium dichloride increases expression ISO PKM (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of PKM protein CTD PMID:24527689 cadmium sulfate multiple interactions EXP 6480464 cadmium sulfate affects the reaction [MTF1 affects the expression of PKM mRNA] CTD PMID:16221973 caffeine increases phosphorylation ISO PKM (Homo sapiens) 6480464 Caffeine results in increased phosphorylation of PKM protein CTD PMID:35688186 carbon nanotube affects expression EXP 6480464 Nanotubes and Carbon affects the expression of PKM protein CTD PMID:21135415 carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 CCCP multiple interactions ISO PKM (Homo sapiens) 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] CTD PMID:34481905 celastrol increases expression EXP 6480464 celastrol results in increased expression of PKM mRNA CTD PMID:35679966 celastrol multiple interactions EXP 6480464 [celastrol co-treated with Dietary Fats] results in increased expression of PKM mRNA CTD PMID:35679966 CGP 52608 multiple interactions ISO PKM (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PKM gene] CTD PMID:28238834 chloromethylisothiazolinone increases metabolic processing ISO PKM (Homo sapiens) 6480464 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of PKM protein CTD PMID:29267982 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PKM mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PKM gene CTD PMID:20938992 cisplatin multiple interactions ISO PKM (Homo sapiens) 6480464 Cisplatin results in increased expression of and results in increased secretion of PKM protein CTD PMID:24980261 clobetasol increases expression EXP 6480464 Clobetasol results in increased expression of PKM mRNA CTD PMID:27462272 clozapine increases expression ISO Pkm (Rattus norvegicus) 6480464 Clozapine results in increased expression of PKM mRNA CTD PMID:15860345 cobalt dichloride decreases expression ISO PKM (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of PKM mRNA CTD PMID:19376846 cocaine affects expression ISO Pkm (Rattus norvegicus) 6480464 Cocaine affects the expression of PKM mRNA CTD PMID:20187946 copper atom affects binding ISO PKM (Homo sapiens) 6480464 PKM protein binds to Copper CTD PMID:15359738 copper(0) affects binding ISO PKM (Homo sapiens) 6480464 PKM protein binds to Copper CTD PMID:15359738 coumarin affects phosphorylation ISO PKM (Homo sapiens) 6480464 coumarin affects the phosphorylation of PKM protein CTD PMID:35688186 coumestrol multiple interactions ISO PKM (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PKM mRNA CTD PMID:19167446 crocidolite asbestos increases expression ISO PKM (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of PKM protein CTD PMID:29553831 curcumin multiple interactions ISO PKM (Homo sapiens) 6480464 ATF4 inhibits the reaction [Curcumin results in decreased expression of PKM protein] more ... CTD PMID:36640941 cyclosporin A multiple interactions ISO PKM (Homo sapiens) 6480464 Cyclosporine results in increased expression of and results in increased secretion of PKM protein CTD PMID:24980261 cyclosporin A increases expression ISO PKM (Homo sapiens) 6480464 Cyclosporine results in increased expression of PKM mRNA CTD PMID:27989131 cyclosporin A decreases expression ISO PKM (Homo sapiens) 6480464 Cyclosporine results in decreased expression of PKM mRNA CTD PMID:21163907 more ... D-glucose increases uptake ISO PKM (Homo sapiens) 6480464 PKM protein results in increased uptake of Glucose CTD PMID:22574221 D-glucose multiple interactions ISO PKM (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [Glucose promotes the reaction [Estradiol results in increased phosphorylation of PKM protein]] more ... CTD PMID:23086999 more ... DDT multiple interactions ISO PKM (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [DDT results in increased expression of and affects the localization of PKM protein alternative form] more ... CTD PMID:31724279 DDT increases expression ISO PKM (Homo sapiens) 6480464 DDT results in increased expression of PKM mRNA alternative form CTD PMID:31724279 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of PKM protein CTD PMID:33567340 dexamethasone multiple interactions ISO PKM (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PKM mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PKM mRNA CTD PMID:28628672 diarsenic trioxide multiple interactions ISO PKM (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PKM mRNA more ... CTD PMID:15894607 and PMID:31003765 diarsenic trioxide decreases expression ISO PKM (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of PKM mRNA and Arsenic Trioxide results in decreased expression of PKM protein CTD PMID:31003765 diarsenic trioxide increases expression ISO PKM (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PKM protein CTD PMID:25419056 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of PKM mRNA CTD PMID:21266533 dichloroacetic acid decreases expression ISO PKM (Homo sapiens) 6480464 Dichloroacetic Acid results in decreased expression of PKM protein CTD PMID:31654802 dicrotophos increases expression ISO PKM (Homo sapiens) 6480464 dicrotophos results in increased expression of PKM mRNA CTD PMID:28302478 dihydroartemisinin affects binding ISO PKM (Homo sapiens) 6480464 artenimol analog binds to PKM protein CTD PMID:26340163 dihydroartemisinin multiple interactions ISO PKM (Homo sapiens) 6480464 PKM protein inhibits the reaction [artenimol results in increased cleavage of CASP3 protein] more ... CTD PMID:34655567 diosmetin increases activity ISO PKM (Homo sapiens) 6480464 diosmetin results in increased activity of PKM protein CTD PMID:25388478 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of PKM mRNA CTD PMID:20880076 dioxygen affects expression ISO PKM (Homo sapiens) 6480464 Oxygen deficiency affects the expression of PKM protein CTD PMID:34900531 dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PKM mRNA CTD PMID:30529165 dioxygen increases expression ISO PKM (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of PKM protein CTD PMID:26087400 dioxygen multiple interactions ISO PKM (Homo sapiens) 6480464 [IL15 protein co-treated with Oxygen deficiency] results in increased expression of PKM mRNA more ... CTD PMID:27129235 and PMID:34900531 diuron increases expression ISO Pkm (Rattus norvegicus) 6480464 Diuron results in increased expression of PKM mRNA CTD PMID:21551480 dopamine increases expression ISO PKM (Homo sapiens) 6480464 Dopamine results in increased expression of PKM protein CTD PMID:24675778 dorsomorphin multiple interactions ISO PKM (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of PKM protein CTD PMID:21251210 doxorubicin decreases expression ISO PKM (Homo sapiens) 6480464 Doxorubicin results in decreased expression of PKM mRNA CTD PMID:29803840 doxorubicin multiple interactions EXP 6480464 sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PKM protein] CTD PMID:21251210 elemental selenium increases expression ISO PKM (Homo sapiens) 6480464 Selenium results in increased expression of PKM mRNA CTD PMID:19244175 emodin affects localization ISO Pkm (Rattus norvegicus) 6480464 Emodin affects the localization of PKM protein CTD PMID:34971761 emodin multiple interactions ISO Pkm (Rattus norvegicus) 6480464 [[Emodin inhibits the reaction [PKM protein binds to PKM protein binds to PKM protein binds to PKM protein]] results in increased abundance of [PKM protein binds to PKM protein]] which binds to NFE2L2 protein more ... CTD PMID:34971761 emodin decreases activity ISO Pkm (Rattus norvegicus) 6480464 Emodin results in decreased activity of PKM protein CTD PMID:34971761 endosulfan increases expression ISO Pkm (Rattus norvegicus) 6480464 Endosulfan results in increased expression of PKM mRNA CTD PMID:29391264 Enterolactone multiple interactions ISO PKM (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PKM mRNA CTD PMID:19167446 enzyme inhibitor multiple interactions ISO PKM (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PKM protein CTD PMID:23301498 ethanol affects splicing EXP 6480464 Ethanol affects the splicing of PKM mRNA CTD PMID:30319688 flavone multiple interactions ISO PKM (Homo sapiens) 6480464 flavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 flavonol multiple interactions ISO PKM (Homo sapiens) 6480464 3-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PKM mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PKM gene CTD PMID:20938992 formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of PKM protein CTD PMID:33259821 formaldehyde increases expression ISO Pkm (Rattus norvegicus) 6480464 Formaldehyde results in increased expression of PKM protein CTD PMID:33259821 FR900359 affects phosphorylation ISO PKM (Homo sapiens) 6480464 FR900359 affects the phosphorylation of PKM protein CTD PMID:37730182 fructose multiple interactions ISO Pkm (Rattus norvegicus) 6480464 [Fructose co-treated with bisphenol A] results in decreased expression of PKM protein CTD PMID:26930160 fulvestrant multiple interactions ISO PKM (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [3 more ... CTD PMID:28284859 and PMID:32078667 fulvestrant multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [bisphenol F results in increased expression of PKM protein] CTD PMID:34147605 Fusaric acid multiple interactions ISO PKM (Homo sapiens) 6480464 Galactose affects the reaction [Fusaric Acid results in increased expression of PKM mRNA] more ... CTD PMID:31654802 Fusaric acid increases expression ISO PKM (Homo sapiens) 6480464 Fusaric Acid results in increased expression of PKM mRNA and Fusaric Acid results in increased expression of PKM protein CTD PMID:31654802 galactose multiple interactions ISO PKM (Homo sapiens) 6480464 Galactose affects the reaction [Fusaric Acid results in increased expression of PKM mRNA] CTD PMID:31654802 gemcitabine affects response to substance ISO PKM (Homo sapiens) 6480464 PKM protein alternative form affects the susceptibility to Gemcitabine CTD PMID:38000456 genistein increases expression ISO Pkm (Rattus norvegicus) 6480464 Genistein results in increased expression of PKM mRNA CTD PMID:12075121 glucose increases uptake ISO PKM (Homo sapiens) 6480464 PKM protein results in increased uptake of Glucose CTD PMID:22574221 glucose multiple interactions ISO PKM (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [Glucose promotes the reaction [Estradiol results in increased phosphorylation of PKM protein]] more ... CTD PMID:23086999 more ... glyphosate increases expression EXP 6480464 Glyphosate results in increased expression of PKM mRNA CTD PMID:36572786 gold atom decreases expression EXP 6480464 Gold analog results in decreased expression of PKM protein CTD PMID:24780912 gold(0) decreases expression EXP 6480464 Gold analog results in decreased expression of PKM protein CTD PMID:24780912 GW 3965 multiple interactions EXP 6480464 GW 3965 inhibits the reaction [3 more ... CTD PMID:27052460 haloperidol increases expression ISO Pkm (Rattus norvegicus) 6480464 Haloperidol results in increased expression of PKM mRNA CTD PMID:15860345 hydrogen peroxide decreases expression ISO Pkm (Rattus norvegicus) 6480464 Hydrogen Peroxide results in decreased expression of PKM protein CTD PMID:23178681 hydrogen peroxide decreases expression ISO PKM (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of PKM protein CTD PMID:34581912 indometacin multiple interactions ISO PKM (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PKM mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PKM mRNA CTD PMID:28628672 ivermectin affects expression ISO PKM (Homo sapiens) 6480464 Ivermectin affects the expression of PKM protein CTD PMID:32959892 L-ascorbic acid increases expression EXP 6480464 Ascorbic Acid results in increased expression of PKM mRNA CTD PMID:22139585 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PKM mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PKM gene CTD PMID:20938992 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of PKM mRNA and Lipopolysaccharides results in increased expression of PKM protein CTD PMID:27339419 and PMID:36762617 lipopolysaccharide multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of PKM protein more ... CTD PMID:36762617 lovastatin decreases expression EXP 6480464 Lovastatin results in decreased expression of PKM mRNA CTD PMID:20493250 luteolin increases activity ISO PKM (Homo sapiens) 6480464 Luteolin results in increased activity of PKM protein CTD PMID:25388478 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol F results in increased expression of PKM mRNA] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol F results in increased expression of PKM protein] CTD PMID:34147605 mercury dichloride multiple interactions ISO PKM (Homo sapiens) 6480464 Mercuric Chloride results in increased expression of and results in increased secretion of PKM protein CTD PMID:24980261 methamphetamine increases expression ISO Pkm (Rattus norvegicus) 6480464 Methamphetamine results in increased expression of PKM protein CTD PMID:19826936 methapyrilene decreases expression ISO Pkm (Rattus norvegicus) 6480464 Methapyrilene results in decreased expression of PKM mRNA CTD PMID:28903497 methidathion increases expression EXP 6480464 methidathion results in increased expression of PKM mRNA CTD PMID:34813904 methoxychlor affects methylation ISO Pkm (Rattus norvegicus) 6480464 Methoxychlor affects the methylation of PKM gene CTD PMID:35440735 methylazoxymethanol increases expression EXP 6480464 methylazoxymethanol results in increased expression of PKM mRNA CTD PMID:17107856 methylmercury chloride increases expression ISO PKM (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of PKM mRNA CTD PMID:28001369 miconazole increases expression EXP 6480464 Miconazole results in increased expression of PKM mRNA CTD PMID:27462272 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of PKM protein]] and Acetylcysteine inhibits the reaction [quinone results in increased degradation of PKM protein] CTD PMID:25437431 and PMID:36762617 N-acetyl-L-cysteine multiple interactions ISO PKM (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:28284859 more ... N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of PKM mRNA and 1-Methyl-4-phenylpyridinium results in decreased expression of PKM protein CTD PMID:17475336 and PMID:22776087 N-methyl-4-phenylpyridinium decreases expression ISO PKM (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of PKM protein CTD PMID:24675778 naphthalene multiple interactions EXP 6480464 [naphthalene co-treated with CFTR gene mutant form] results in decreased expression of PKM protein CTD PMID:19438287 nickel dichloride multiple interactions EXP 6480464 HIF1A affects the reaction [nickel chloride results in increased expression of PKM mRNA] CTD PMID:12426141 and PMID:12729255 nickel dichloride increases expression EXP 6480464 nickel chloride results in increased expression of PKM mRNA CTD PMID:12426141 more ... nickel subsulfide affects expression EXP 6480464 nickel subsulfide affects the expression of PKM mRNA CTD PMID:12729255 niclosamide increases expression ISO PKM (Homo sapiens) 6480464 Niclosamide results in increased expression of PKM mRNA CTD PMID:22576131 ochratoxin A multiple interactions ISO PKM (Homo sapiens) 6480464 ochratoxin A results in increased phosphorylation of and results in decreased activity of and affects the localization of PKM protein CTD PMID:32835834 ozone multiple interactions ISO PKM (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PKM mRNA more ... CTD PMID:32699268 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of PKM mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of PKM mRNA CTD PMID:34911549 paclitaxel affects response to substance ISO PKM (Homo sapiens) 6480464 PKM protein affects the susceptibility to Paclitaxel CTD PMID:16217747 panobinostat increases expression ISO PKM (Homo sapiens) 6480464 panobinostat results in increased expression of PKM mRNA CTD PMID:26272509 panobinostat multiple interactions ISO PKM (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKM mRNA CTD PMID:27188386 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of PKM mRNA CTD PMID:17562736 paracetamol decreases expression ISO Pkm (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of PKM mRNA CTD PMID:33387578 paraquat increases expression ISO Pkm (Rattus norvegicus) 6480464 Paraquat results in increased expression of PKM mRNA CTD PMID:32680482 PCB138 decreases expression ISO Pkm (Rattus norvegicus) 6480464 2 more ... CTD PMID:21673325 perfluorooctane-1-sulfonic acid increases expression ISO PKM (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in increased expression of PKM mRNA CTD PMID:27153767 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PKM mRNA CTD PMID:36331819 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of PKM mRNA CTD PMID:19363144 phenylmercury acetate increases expression ISO PKM (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of PKM mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO PKM (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKM mRNA CTD PMID:27188386 PhIP increases expression ISO Pkm (Rattus norvegicus) 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of PKM mRNA CTD PMID:15215175 phosphoenolpyruvate increases metabolic processing ISO PKM (Homo sapiens) 6480464 PKM protein results in increased metabolism of Phosphoenolpyruvate CTD PMID:25388478 phosphoenolpyruvate multiple interactions ISO PKM (Homo sapiens) 6480464 3-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] more ... CTD PMID:25388478 potassium dichromate increases expression ISO PKM (Homo sapiens) 6480464 Potassium Dichromate results in increased expression of PKM protein CTD PMID:20332019 more ... potassium dichromate multiple interactions ISO PKM (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [Potassium Dichromate results in increased expression of PKM protein] more ... CTD PMID:32569804 and PMID:36473502 progesterone affects expression EXP 6480464 Progesterone affects the expression of PKM mRNA CTD PMID:17251523 promethazine decreases expression ISO Pkm (Rattus norvegicus) 6480464 Promethazine results in decreased expression of PKM mRNA CTD PMID:28903497 Propiverine affects binding ISO Pkm (Rattus norvegicus) 6480464 propiverine binds to PKM protein CTD PMID:29273565 quartz affects expression ISO PKM (Homo sapiens) 6480464 Quartz affects the expression of PKM protein CTD PMID:27917503 quercetin decreases expression ISO PKM (Homo sapiens) 6480464 Quercetin results in decreased expression of PKM protein CTD PMID:15221776 and PMID:35945655 quercetin multiple interactions ISO PKM (Homo sapiens) 6480464 G3BP1 protein inhibits the reaction [Quercetin results in decreased expression of PKM protein] CTD PMID:35945655 quercetin increases expression ISO PKM (Homo sapiens) 6480464 Quercetin results in increased expression of PKM mRNA and Quercetin results in increased expression of PKM protein CTD PMID:14750173 and PMID:21632981 rac-lactic acid increases abundance ISO PKM (Homo sapiens) 6480464 PKM protein results in increased abundance of Lactic Acid CTD PMID:22574221 rac-lactic acid increases expression ISO PKM (Homo sapiens) 6480464 Lactic Acid results in increased expression of PKM protein CTD PMID:36336208 rac-lactic acid multiple interactions ISO PKM (Homo sapiens) 6480464 Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] more ... CTD PMID:36336208 reactive oxygen species multiple interactions EXP 6480464 Reactive Oxygen Species affects the reaction [quinone results in increased degradation of PKM protein] CTD PMID:25437431 resveratrol multiple interactions ISO PKM (Homo sapiens) 6480464 [resveratrol results in decreased activity of MTOR protein] which results in decreased expression of PKM mRNA and [resveratrol results in decreased activity of MTOR protein] which results in decreased expression of PKM protein CTD PMID:22574221 resveratrol increases expression ISO Pkm (Rattus norvegicus) 6480464 resveratrol results in increased expression of PKM mRNA CTD PMID:25905778 resveratrol decreases response to substance ISO PKM (Homo sapiens) 6480464 PKM protein results in decreased susceptibility to resveratrol CTD PMID:22574221 rotenone increases oxidation ISO Pkm (Rattus norvegicus) 6480464 Rotenone results in increased oxidation of PKM protein CTD PMID:30951809 SAICAR multiple interactions ISO PKM (Homo sapiens) 6480464 Glucose deficiency promotes the reaction [SAICAR binds to and results in increased activity of PKM protein] CTD PMID:23086999 SB 431542 multiple interactions ISO PKM (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 and PMID:37664457 scutellarin increases activity ISO PKM (Homo sapiens) 6480464 scutellarin results in increased activity of PKM protein CTD PMID:25388478 selenium atom increases expression ISO PKM (Homo sapiens) 6480464 Selenium results in increased expression of PKM mRNA CTD PMID:19244175 Shikonin multiple interactions EXP 6480464 shikonin inhibits the reaction [[Tobacco Smoke Pollution results in increased abundance of Particulate Matter] which results in increased expression of PKM protein] CTD PMID:35787437 silicon dioxide increases secretion ISO PKM (Homo sapiens) 6480464 Silicon Dioxide analog results in increased secretion of PKM protein CTD PMID:25895662 silicon dioxide affects expression ISO PKM (Homo sapiens) 6480464 Silicon Dioxide affects the expression of PKM protein CTD PMID:27917503 sirolimus multiple interactions ISO PKM (Homo sapiens) 6480464 [Sirolimus results in decreased activity of MTOR protein] which results in decreased expression of PKM protein more ... CTD PMID:22574221 more ... sirolimus increases expression ISO PKM (Homo sapiens) 6480464 Sirolimus results in increased expression of PKM protein CTD PMID:36640941 sodium arsenite affects expression EXP 6480464 sodium arsenite affects the expression of PKM mRNA CTD PMID:17450228 sodium arsenite decreases expression ISO PKM (Homo sapiens) 6480464 sodium arsenite results in decreased expression of PKM mRNA CTD PMID:37956786 sodium arsenite affects expression ISO PKM (Homo sapiens) 6480464 sodium arsenite affects the expression of PKM mRNA CTD PMID:34032870 sodium arsenite decreases expression ISO Pkm (Rattus norvegicus) 6480464 sodium arsenite results in decreased expression of PKM mRNA and sodium arsenite results in decreased expression of PKM protein CTD PMID:29459688 and PMID:35314868 sodium arsenite increases expression ISO PKM (Homo sapiens) 6480464 sodium arsenite results in increased expression of PKM mRNA CTD PMID:28595984 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of PKM protein CTD PMID:27548804 sodium nitrate multiple interactions EXP 6480464 sodium nitrate inhibits the reaction [Doxorubicin results in increased expression of PKM protein] CTD PMID:21251210 streptozocin affects expression EXP 6480464 Streptozocin affects the expression of PKM mRNA CTD PMID:18583417 sulindac sulfide decreases expression ISO PKM (Homo sapiens) 6480464 sulindac sulfide results in decreased expression of PKM mRNA CTD PMID:16184548 sunitinib increases expression ISO PKM (Homo sapiens) 6480464 Sunitinib results in increased expression of PKM mRNA CTD PMID:31533062 T-2 toxin affects expression ISO Pkm (Rattus norvegicus) 6480464 T-2 Toxin affects the expression of PKM protein CTD PMID:26141394 tanespimycin decreases expression ISO PKM (Homo sapiens) 6480464 tanespimycin results in decreased expression of PKM protein CTD PMID:31370342 tangeretin increases activity ISO PKM (Homo sapiens) 6480464 tangeretin results in increased activity of PKM protein CTD PMID:25388478 temozolomide decreases expression ISO PKM (Homo sapiens) 6480464 Temozolomide results in decreased expression of PKM mRNA CTD PMID:31758290 tetrachloromethane increases expression ISO Pkm (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of PKM protein CTD PMID:12629582 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of PKM mRNA CTD PMID:27339419 and PMID:31919559 thapsigargin decreases expression ISO PKM (Homo sapiens) 6480464 Thapsigargin results in decreased expression of PKM mRNA CTD PMID:22378314 thapsigargin increases expression ISO Pkm (Rattus norvegicus) 6480464 Thapsigargin results in increased expression of PKM protein CTD PMID:35544339 thioacetamide increases expression ISO Pkm (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of PKM mRNA CTD PMID:28903497 and PMID:34492290 tributylstannane increases expression EXP 6480464 tributyltin results in increased expression of PKM mRNA CTD PMID:31939706 trichloroethene affects expression EXP 6480464 Trichloroethylene affects the expression of PKM mRNA CTD PMID:21135412 trichostatin A increases expression ISO PKM (Homo sapiens) 6480464 trichostatin A results in increased expression of PKM mRNA CTD PMID:24935251 and PMID:26272509 trichostatin A multiple interactions ISO PKM (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKM mRNA CTD PMID:27188386 triclosan decreases expression ISO PKM (Homo sapiens) 6480464 Triclosan results in decreased expression of PKM mRNA CTD PMID:30510588 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of PKM mRNA CTD PMID:19042947 triphenylstannane decreases expression ISO PKM (Homo sapiens) 6480464 triphenyltin analog results in decreased expression of PKM protein CTD PMID:31634547 Triptolide decreases expression EXP 6480464 triptolide results in decreased expression of PKM mRNA CTD PMID:34087332 tunicamycin decreases expression ISO PKM (Homo sapiens) 6480464 Tunicamycin results in decreased expression of PKM mRNA CTD PMID:22378314 tunicamycin increases expression ISO PKM (Homo sapiens) 6480464 Tunicamycin results in increased expression of PKM protein CTD PMID:36473502 ubiquinone-0 decreases expression ISO PKM (Homo sapiens) 6480464 ubiquinone-O results in decreased expression of PKM protein CTD PMID:36847822 undecane decreases expression ISO Pkm (Rattus norvegicus) 6480464 undecane results in decreased expression of PKM protein CTD PMID:17337753 valproic acid increases expression ISO PKM (Homo sapiens) 6480464 Valproic Acid results in increased expression of PKM mRNA CTD PMID:23179753 more ... valproic acid multiple interactions ISO PKM (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKM mRNA CTD PMID:27188386 vitamin E increases expression ISO PKM (Homo sapiens) 6480464 Vitamin E results in increased expression of PKM mRNA CTD PMID:19244175 vorinostat increases expression ISO PKM (Homo sapiens) 6480464 vorinostat results in increased expression of PKM mRNA CTD PMID:26272509 vorinostat multiple interactions ISO PKM (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKM mRNA CTD PMID:27188386 warfarin decreases expression EXP 6480464 Warfarin results in decreased expression of PKM mRNA CTD PMID:20493250 wogonin multiple interactions ISO PKM (Homo sapiens) 6480464 wogonin inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 Yessotoxin increases expression ISO PKM (Homo sapiens) 6480464 yessotoxin analog results in increased expression of PKM mRNA CTD PMID:30679557 zinc atom decreases expression ISO PKM (Homo sapiens) 6480464 Zinc results in decreased expression of PKM protein CTD PMID:15984569 zinc(0) decreases expression ISO PKM (Homo sapiens) 6480464 Zinc results in decreased expression of PKM protein CTD PMID:15984569
