MAMMALIAN PHENOTYPE - ANNOTATIONS
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term: increased cytokine level
Accession: MP:0014433
browse the term
Definition: more than the normal levels of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells
Synonyms: exact_synonym: elevated cytokine level
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Fibcd1
fibrinogen C domain containing 1
IAGP
MGI
PMID:34937773
NCBI chr 2:31,703,302...31,736,976
Ensembl chr 2:31,703,302...31,736,017
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Fmo1
flavin containing monooxygenase 1
IAGP
MGI
PMID:34500002
NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179
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Rab11a
RAB11A, member RAS oncogene family
IAGP
MGI
PMID:31239271
NCBI chr 9:64,622,582...64,645,038
Ensembl chr 9:64,622,581...64,645,040
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Ttc39aos1
Ttc39a opposite strand RNA 1
IAGP
MGI
PMID:33512718
NCBI chr 4:109,259,476...109,263,454
Ensembl chr 4:109,259,476...109,263,430
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Apoe
apolipoprotein E
IAGP
MGI
PMID:32686880
NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
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Thbs4
thrombospondin 4
IAGP
MGI
PMID:32686880
NCBI chr13:92,888,094...92,931,326
Ensembl chr13:92,888,098...92,931,326
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Tmem268
transmembrane protein 268
IAGP
MGI
PMID:38730209
NCBI chr 4:63,472,410...63,504,594
Ensembl chr 4:63,477,018...63,504,594
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Alpk1
alpha-kinase 1
IAGP
MGI
PMID:35868845
NCBI chr 3:127,460,367...127,574,195
Ensembl chr 3:127,463,959...127,574,176
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Asah1
N-acylsphingosine amidohydrolase 1
IAGP
MGI
PMID:29908121
NCBI chr 8:41,793,683...41,850,681
Ensembl chr 8:41,793,234...41,827,810
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Cav1
caveolin 1, caveolae protein
IAGP
MGI
PMID:16982844
NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
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Crb1
crumbs family member 1, photoreceptor morphogenesis associated
IAGP
MGI
PMID:35868845
NCBI chr 1:139,101,288...139,307,262
Ensembl chr 1:139,124,794...139,304,838
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Cyrib
CYFIP related Rac1 interactor B
IAGP
MGI
PMID:31285585
NCBI chr15:63,800,943...63,932,627
Ensembl chr15:63,800,946...63,932,327
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Gpr182
G protein-coupled receptor 182
IAGP
MGI
PMID:33875597
NCBI chr10:127,585,471...127,587,667
Ensembl chr10:127,583,145...127,587,601
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Lyz2
lysozyme 2
IAGP
MGI
PMID:31285585
NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
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Pld3
phospholipase D family member 3
IAGP
MGI
PMID:30111894
NCBI chr 7:27,231,090...27,252,511
Ensembl chr 7:27,231,425...27,252,643
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Pld4
phospholipase D family member 4
IAGP
MGI
PMID:30111894
NCBI chr12:112,727,089...112,735,420
Ensembl chr12:112,727,089...112,735,424
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Sros1
non-coding RNA suppressor of Stat1
IAGP
MGI
PMID:31740800
NCBI chr10:122,400,928...122,405,796
Ensembl chr10:122,400,928...122,405,796
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Adar
adenosine deaminase, RNA-specific
IAGP
MGI
PMID:19060901
NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753
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Ddx60
DExD/H box helicase 60
IAGP
MGI
PMID:25981042
NCBI chr 8:62,381,155...62,491,278
Ensembl chr 8:62,381,121...62,491,278
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Fas
Fas cell surface death receptor
IAGP
MGI
PMID:16973389
NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
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Gpr183
G protein-coupled receptor 183
IAGP
MGI
PMID:24386204
NCBI chr14:122,189,743...122,202,605
Ensembl chr14:122,189,963...122,202,607
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Lsm3
LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
IAGP
MGI
PMID:29706547
NCBI chr 6:91,493,017...91,499,602
Ensembl chr 6:91,492,910...91,499,607
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Phf6
PHD finger protein 6
IAGP
MGI
PMID:30755422
NCBI chr X:52,001,091...52,045,838
Ensembl chr X:52,001,143...52,045,820
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Pik3cd
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
IEA
MGI
NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028
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Prf1
perforin 1 (pore forming protein)
IAGP
MGI
PMID:15069016
NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
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Rnf122
ring finger protein 122
IAGP
MGI
PMID:27506794
NCBI chr 8:31,601,855...31,623,346
Ensembl chr 8:31,601,848...31,621,510
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Siglech
sialic acid binding Ig-like lectin H
IAGP
MGI
PMID:22177923
NCBI chr 7:55,417,916...55,429,196
Ensembl chr 7:55,417,926...55,428,673
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Tlr9
toll-like receptor 9
IAGP
MGI
PMID:16973389
NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
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Trim38
tripartite motif-containing 38
IAGP
MGI
PMID:26392463
NCBI chr13:23,962,483...23,975,721
Ensembl chr13:23,953,896...23,975,511
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Ube2s
ubiquitin-conjugating enzyme E2S
IAGP
MGI
PMID:32814047
NCBI chr 7:4,811,013...4,815,339
Ensembl chr 7:4,797,545...4,815,589
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Usp21
ubiquitin specific peptidase 21
IAGP
MGI
PMID:24493797
NCBI chr 1:171,109,523...171,115,534
Ensembl chr 1:171,109,519...171,115,564
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Ccdc50
coiled-coil domain containing 50
IAGP
MGI
PMID:34453126
NCBI chr16:27,205,815...27,270,968
Ensembl chr16:27,207,619...27,270,968
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Ddx46
DEAD box helicase 46
IAGP
MGI
PMID:28846086
NCBI chr13:55,782,790...55,829,080
Ensembl chr13:55,782,841...55,829,069
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Fis1
fission, mitochondrial 1
IAGP
MGI
PMID:31526891
NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
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Irf9
interferon regulatory factor 9
IEA
MGI
NCBI chr14:55,841,442...55,847,487
Ensembl chr14:55,841,028...55,847,487
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Lsm3
LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
IAGP
MGI
PMID:29706547
NCBI chr 6:91,493,017...91,499,602
Ensembl chr 6:91,492,910...91,499,607
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Lyz2
lysozyme 2
IAGP
MGI
PMID:36028484
NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
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Marchf2
membrane associated ring-CH-type finger 2
IAGP
MGI
PMID:32935379
NCBI chr17:33,904,666...33,937,651
Ensembl chr17:33,904,666...33,937,644
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Marchf5
membrane associated ring-CH-type finger 5
IAGP
MGI
PMID:26246171
NCBI chr19:37,184,939...37,201,856
Ensembl chr19:37,184,942...37,199,550
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Mmp9
matrix metallopeptidase 9
IAGP
MGI
PMID:18332263
NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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Otud1
OTU domain containing 1
IAGP
MGI
PMID:32075857
NCBI chr 2:19,662,542...19,666,090
Ensembl chr 2:19,662,563...19,665,394
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Prmt9
protein arginine methyltransferase 9
IAGP
MGI
PMID:36028484
NCBI chr 8:78,276,015...78,307,966
Ensembl chr 8:78,276,026...78,307,967
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Rnf115
ring finger protein 115
IAGP
MGI
PMID:33139700
NCBI chr 3:96,634,869...96,698,471
Ensembl chr 3:96,634,980...96,698,954
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Rnf122
ring finger protein 122
IAGP
MGI
PMID:27506794
NCBI chr 8:31,601,855...31,623,346
Ensembl chr 8:31,601,848...31,621,510
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Snrnp40
small nuclear ribonucleoprotein 40 (U5)
IAGP
MGI
PMID:31427773
NCBI chr 4:130,253,925...130,283,826
Ensembl chr 4:130,253,925...130,283,819
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Tmem268
transmembrane protein 268
IAGP
MGI
PMID:38730209
NCBI chr 4:63,472,410...63,504,594
Ensembl chr 4:63,477,018...63,504,594
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Trim38
tripartite motif-containing 38
IAGP
MGI
PMID:26392463
NCBI chr13:23,962,483...23,975,721
Ensembl chr13:23,953,896...23,975,511
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Ube2s
ubiquitin-conjugating enzyme E2S
IAGP
MGI
PMID:32814047
NCBI chr 7:4,811,013...4,815,339
Ensembl chr 7:4,797,545...4,815,589
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Usp21
ubiquitin specific peptidase 21
IAGP
MGI
PMID:24493797
NCBI chr 1:171,109,523...171,115,534
Ensembl chr 1:171,109,519...171,115,564
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Usp49
ubiquitin specific peptidase 49
IAGP
MGI
PMID:30943264
NCBI chr17:47,941,615...47,997,664
Ensembl chr17:47,941,615...47,997,663
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Wwp2
WW domain containing E3 ubiquitin protein ligase 2
IAGP
MGI
PMID:23479606
NCBI chr 8:108,162,966...108,285,922
Ensembl chr 8:108,162,997...108,285,227
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Ace2
angiotensin converting enzyme 2
IAGP
MGI
PMID:32485164
NCBI chr X:162,922,338...162,971,414
Ensembl chr X:162,922,328...162,971,416
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Apoe
apolipoprotein E
IAGP
MGI
PMID:12765335
NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
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Cav1
caveolin 1, caveolae protein
IAGP
MGI
PMID:16982844
NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
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Ccl2
C-C motif chemokine ligand 2
IAGP
MGI
PMID:19641038
NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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Cd44
CD44 antigen
IAGP
MGI
PMID:11342603
NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
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Cd79a
CD79A antigen (immunoglobulin-associated alpha)
IAGP
MGI
PMID:23955076
NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
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Dhx58
DExH-box helicase 58
IAGP
MGI
PMID:17475874
NCBI chr11:100,585,710...100,595,165
Ensembl chr11:100,585,710...100,595,097
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Dusp1
dual specificity phosphatase 1
IAGP
MGI
PMID:16424221
NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
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Dusp22
dual specificity phosphatase 22
IAGP
MGI
PMID:24714587
NCBI chr13:30,844,042...30,895,215
Ensembl chr13:30,843,982...30,895,214
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Foxp3
forkhead box P3
IAGP
MGI
PMID:16275384 PMID:34709178
NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484
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Gba1
glucosylceramidase beta 1
IAGP
MGI
PMID:20962279
NCBI chr 3:89,110,235...89,119,944
Ensembl chr 3:89,110,235...89,116,273
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Gnai2
G protein subunit alpha i2
IAGP
MGI
PMID:17242370
NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
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Gpr183
G protein-coupled receptor 183
IAGP
MGI
PMID:24386204
NCBI chr14:122,189,743...122,202,605
Ensembl chr14:122,189,963...122,202,607
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Gt(ROSA)26Sor
gene trap ROSA 26, Philippe Soriano
IAGP
MGI
PMID:23955076 PMID:24376268 PMID:24498102 PMID:29263322
NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336
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Ifngr1
interferon gamma receptor 1
IAGP
MGI
PMID:31964735
NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
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Igtp
interferon gamma induced GTPase
IAGP
MGI
PMID:10639151
NCBI chr11:58,090,382...58,098,418
Ensembl chr11:58,090,382...58,098,417
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Il10
interleukin 10
IAGP
MGI
PMID:12765335 PMID:19941312
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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Il10ra
interleukin 10 receptor, alpha
IAGP
MGI
PMID:19941312
NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447
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Il10rb
interleukin 10 receptor, beta
IAGP
MGI
PMID:18318596
NCBI chr16:91,203,166...91,222,718
Ensembl chr16:91,203,052...91,222,722
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Il18bp
interleukin 18 binding protein
IAGP
MGI
PMID:28900426 PMID:29295842
NCBI chr 7:101,664,281...101,669,699
Ensembl chr 7:101,664,092...101,667,897
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Il27ra
interleukin 27 receptor, alpha
IAGP
MGI
PMID:15004160
NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218
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Irf1
interferon regulatory factor 1
IAGP
MGI
PMID:9379011
NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
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Irgm1
immunity-related GTPase family M member 1
IAGP
MGI
PMID:11457893
NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510
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Klra8
killer cell lectin-like receptor, subfamily A, member 8
IAGP
MGI
PMID:15784573
NCBI chr 6:130,092,189...130,106,861
Ensembl chr 6:130,092,189...130,106,861
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Lgals3bp
lectin, galactoside-binding, soluble, 3 binding protein
IAGP
MGI
PMID:10077627
NCBI chr11:118,283,573...118,292,787
Ensembl chr11:118,283,577...118,292,918
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Lyn
LYN proto-oncogene, Src family tyrosine kinase
IAGP
MGI
PMID:23940344
NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122
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Lyz2
lysozyme 2
IAGP
MGI
PMID:19941312 PMID:29263322
NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
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Mavs
mitochondrial antiviral signaling protein
IAGP
MGI
PMID:20140199
NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945
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Mmp9
matrix metallopeptidase 9
IAGP
MGI
PMID:18332263
NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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Mst1r
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
IAGP
MGI
PMID:17008558
NCBI chr 9:107,784,057...107,797,582
Ensembl chr 9:107,784,072...107,797,582
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Mta2
metastasis-associated gene family, member 2
IAGP
MGI
PMID:18353770
NCBI chr19:8,919,239...8,929,659
Ensembl chr19:8,919,239...8,929,667
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Muc5ac
mucin 5, subtypes A and C, tracheobronchial/gastric
IAGP
MGI
PMID:21502330
NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
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Nfil3
nuclear factor, interleukin 3, regulated
IAGP
MGI
PMID:24442434
NCBI chr13:53,121,245...53,136,914
Ensembl chr13:53,121,245...53,135,109
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Nod2
nucleotide-binding oligomerization domain containing 2
IAGP
MGI
PMID:19139201
NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102
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Pcsk1
proprotein convertase subtilisin/kexin type 1
IAGP
MGI
PMID:22396549
NCBI chr13:75,237,407...75,282,980
Ensembl chr13:75,237,945...75,282,980
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Pgd
phosphogluconate dehydrogenase
IAGP
MGI
PMID:34709178
NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228
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Pilrb1
paired immunoglobin-like type 2 receptor beta 1
IAGP
MGI
PMID:20065029
NCBI chr 5:137,850,403...137,856,687
Ensembl chr 5:137,850,409...137,856,368
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Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
IAGP
MGI
PMID:27313209
NCBI chr10:127,032,936...127,047,508
Ensembl chr10:127,032,936...127,047,454
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Pld3
phospholipase D family member 3
IAGP
MGI
PMID:30111894
NCBI chr 7:27,231,090...27,252,511
Ensembl chr 7:27,231,425...27,252,643
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Pld4
phospholipase D family member 4
IAGP
MGI
PMID:30111894
NCBI chr12:112,727,089...112,735,420
Ensembl chr12:112,727,089...112,735,424
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Prf1
perforin 1 (pore forming protein)
IAGP
MGI
PMID:15069016 PMID:23160464
NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
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Ptpn6
protein tyrosine phosphatase, non-receptor type 6
IAGP
MGI
PMID:21435452
NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677
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Pycard
PYD and CARD domain containing
IAGP
MGI
PMID:29263322
NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
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Rab27a
RAB27A, member RAS oncogene family
IAGP
MGI
PMID:23160464
NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911
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Ramp1
receptor (calcitonin) activity modifying protein 1
IAGP
MGI
PMID:17923674
NCBI chr 1:91,107,544...91,152,918
Ensembl chr 1:91,107,544...91,152,918
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Rhbdd3
rhomboid domain containing 3
IAGP
MGI
PMID:23610400
NCBI chr11:5,048,282...5,056,100
Ensembl chr11:5,048,926...5,056,093
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Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
IAGP
MGI
PMID:19923443
NCBI chr16:75,655,682...75,706,154
Ensembl chr16:75,655,681...75,819,169
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Sirt3
sirtuin 3
IAGP
MGI
PMID:21856199
NCBI chr 7:140,443,576...140,462,222
Ensembl chr 7:140,443,579...140,462,222
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Snrnp40
small nuclear ribonucleoprotein 40 (U5)
IAGP
MGI
PMID:31427773
NCBI chr 4:130,253,925...130,283,826
Ensembl chr 4:130,253,925...130,283,819
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Socs1
suppressor of cytokine signaling 1
IAGP
MGI
PMID:12705851
NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400
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Socs2
suppressor of cytokine signaling 2
IAGP
MGI
PMID:22562833
NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042
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Stat1
signal transducer and activator of transcription 1
IAGP
MGI
PMID:12370359 PMID:14670297
NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
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Stat3
signal transducer and activator of transcription 3
IAGP
MGI
PMID:12571365
NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
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Stat6
signal transducer and activator of transcription 6
IAGP
MGI
PMID:16275384
NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826
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Stx11
syntaxin 11
IAGP
MGI
PMID:23160464
NCBI chr10:12,813,961...12,840,242
Ensembl chr10:12,813,953...12,840,042
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Tlr7
toll-like receptor 7
IAGP
MGI
PMID:35477763
NCBI chr X:166,086,376...166,113,570
Ensembl chr X:166,087,925...166,113,554
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Tnfaip3
tumor necrosis factor, alpha-induced protein 3
IAGP
MGI
PMID:24498102
NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405
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Tnfrsf10b
tumor necrosis factor receptor superfamily, member 10b
IAGP
MGI
PMID:15589175
NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860
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Tnk2
tyrosine kinase, non-receptor, 2
IAGP
MGI
PMID:36376335
NCBI chr16:32,462,699...32,502,311
Ensembl chr16:32,462,692...32,502,311
G
Trp53
transformation related protein 53
IAGP
MGI
PMID:21411755
NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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Vav1
vav 1 oncogene
IAGP
MGI
PMID:20009105
NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031
G
Zc3h12c
zinc finger CCCH type containing 12C
IAGP
MGI
PMID:31126966
NCBI chr 9:52,020,869...52,080,028
Ensembl chr 9:52,022,644...52,079,872
G
Zg16
zymogen granule protein 16
IAGP
MGI
PMID:27849619
NCBI chr 7:126,649,328...126,651,847
Ensembl chr 7:126,649,328...126,686,500
G
Adar
adenosine deaminase, RNA-specific
IAGP
MGI
PMID:34332594
NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753
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Aire
autoimmune regulator
IAGP
MGI
PMID:22490868
NCBI chr10:77,865,856...77,879,444
Ensembl chr10:77,865,856...77,879,444
G
Tnk2
tyrosine kinase, non-receptor, 2
IAGP
MGI
PMID:36376335
NCBI chr16:32,462,699...32,502,311
Ensembl chr16:32,462,692...32,502,311
G
Trim29
tripartite motif-containing 29
IAGP
MGI
PMID:38664417
NCBI chr 9:43,222,012...43,247,422
Ensembl chr 9:43,222,145...43,247,412
G
Ube2s
ubiquitin-conjugating enzyme E2S
IAGP
MGI
PMID:32814047
NCBI chr 7:4,811,013...4,815,339
Ensembl chr 7:4,797,545...4,815,589
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