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Term:
Parent Terms Term With Siblings Child Terms
decreased circulating CXCL10 level  
increased circulating CCL3 level  
increased circulating CXCL10 level  
elevation in the blood levels of CXCL10 protein, a pro-inflammatory cytokine that is secreted by a wide range of cell types in response to interferon-gamma, and produces its effects by binding to the cell surface chemokine receptor CXCR3; this chemokine is involved in a variety of processes including chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects, and plays an important role during viral infections by stimulating the activation and migration of immune cells to infected sites

Synonyms
Exact Synonyms: elevated circulating CXCL10 level ;   increased circulating C-X-C motif chemokine ligand 10 level ;   increased circulating IFN gamma-inducible protein 10 level ;   increased circulating IP-10 level ;   increased circulating IP10 level ;   increased circulating gamma-IP10 level ;   increased circulating interferon gamma-induced protein 10 level ;   increased circulating small-inducible cytokine B10 level
Narrow Synonyms: Abnormality of serum cytokine level
Xrefs: HP:0011112
Definition Sources: https://www.prospecbio.com/ip-10, https://www.uniprot.org/uniprot/P02778

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