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Gene: Mta2 (metastasis-associated gene family, member 2) Mus musculus
Symbol: Mta2
Name: metastasis-associated gene family, member 2
Description: Exhibits histone deacetylase activity; transcription coregulator activity; and transcription regulatory region DNA binding activity. Predicted to contribute to transcription regulatory region sequence-specific DNA binding activity. Involved in DNA methylation; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Localizes to the NuRD complex. Used to study systemic lupus erythematosus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; limb; and retina. Orthologous to human MTA2 (metastasis associated 1 family member 2); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one.
Type: protein-coding
Also known as: AW550797; Mata1l1; metastais-associated gene family, member 2; metastasis associated 1-like 1; metastasis-associated 1-like 1; metastasis-associated protein 2; metastasis-associated protein MTA2; mmta2; Mta1l1
Homo sapiens (human) : MTA2 (metastasis associated 1 family member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mta2 (metastasis associated 1 family, member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mta2 (metastasis associated 1 family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MTA2 (metastasis associated 1 family member 2)
Canis lupus familiaris (dog) : MTA2 (metastasis associated 1 family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mta2 (metastasis associated 1 family member 2)
Sus scrofa (pig) : MTA2 (metastasis associated 1 family member 2)
Chlorocebus sabaeus (green monkey) : MTA2 (metastasis associated 1 family member 2)
Heterocephalus glaber (naked mole-rat) : Mta2 (metastasis associated 1 family member 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl198,941,875 - 8,952,303 (+)Ensembl
GRCm38198,941,920 - 8,952,300 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37199,016,410 - 9,026,790 (+)NCBIGRCm37mm9NCBIm37
MGSCv36199,008,965 - 9,019,345 (+)NCBImm8
Celera198,702,694 - 8,712,899 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mta2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315536
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.