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Gene: Rab27a (RAB27A, member RAS oncogene family) Mus musculus
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Symbol: Rab27a
Name: RAB27A, member RAS oncogene family
Description: The protein encoded by this gene is a member of the Rab family of proteins, which is the largest family within the Ras superfamily of GTPases. This gene product is thought to regulate vesicular transport, together with its specific effectors. Mutations in this gene cause several defects, including actin-based melanosome transport defects and immunodeficiency. Mutations in the human ortholog of this gene are associated with Griscelli syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2210402C08Rik; 2410003M20Rik; 4933437C11Rik; ash; ashen; ras-related protein Rab-27A
Orthologs:
Homo sapiens (human) : RAB27A (RAB27A, member RAS oncogene family)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rab27a (RAB27A, member RAS oncogene family)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rab27a (RAB27A, member RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAB27A (RAB27A, member RAS oncogene family)
Canis lupus familiaris (dog) : RAB27A (RAB27A, member RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rab27a (RAB27A, member RAS oncogene family)
Sus scrofa (pig) : RAB27A (RAB27A, member RAS oncogene family)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38973,044,810 - 73,097,623 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37972,892,672 - 72,945,399 (+)NCBIGRCm37mm9NCBIm37
MGSCv36972,841,997 - 72,894,724 (+)NCBImm8
Celera970,230,976 - 70,283,828 (+)NCBICelera
Cytogenetic Map9 DNCBI
cM Map940.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rab27a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551470
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.