| 620645 | Sf1 | splicing factor 1 | ENCODES a protein that exhibits identical protein binding (ortholog); RNA binding (ortholog); INVOLVED IN negative regulation of smooth muscle cell proliferation; Leydig cell differentiation (ortholog); male sex determination (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH ischemia; melanoma (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); spliceosomal complex (ortholog); INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol | 1 | 213090256 | 213112688 | Rat | 161 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1311245 | Rsf1 | remodeling and spacing factor 1 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); histone binding (ortholog); histone octamer slider activity (ortholog); INVOLVED IN chromatin organization (ortholog); chromatin remodeling (ortholog); DNA-templated transcription initiation (ortholog); FOUND IN nucleoplasm (ortholo g); nucleus (ortholog); RSF complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Butylbenzyl phthalate | 1 | 161303596 | 161426326 | Rat | 129 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 620974 | Usf1 | upstream transcription factor 1 | ENCODES a protein that exhibits DNA binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; INVOLVED IN glucose metabolic process; positive regulation of transcription by RNA polymerase II; regulation of DNA-templated transcription; ASSOCIATED WITH cardiovascular system disease (ortholog); familial combined hyperlipidemia (ortholog); Hyperlipidemia, Combined, 1 (ortholog); FOUND IN chromatin (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine | 13 | 86377679 | 86385523 | Rat | 163 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 631402 | Igsf1 | immunoglobulin superfamily, member 1 | ENCODES a protein that exhibits coreceptor activity; activin receptor antagonist activity (ortholog); inhibin binding (ortholog); INVOLVED IN negative regulation of activin receptor signaling pathway (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH congenital hypothy roidism (ortholog); Congenital Nongoitrous Hypothyroidism (ortholog); congenital nongoitrous hypothyroidism 1 (ortholog); FOUND IN membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol | X | 133947717 | 133963154 | Rat | 110 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 735030 | Igsf10 | immunoglobulin superfamily, member 10 | INVOLVED IN ossification; tissue regeneration; regulation of neuron migration (ortholog); ASSOCIATED WITH Martsolf syndrome 1 (ortholog); Primary Ovarian Failure (ortholog); primary ovarian insufficiency (ortholog); FOUND IN extracellular region (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 1 7beta-estradiol; 17beta-estradiol 3-benzoate | 2 | 145725868 | 145754850 | Rat | 87 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1308758 | Igsf11 | immunoglobulin superfamily, member 11 | ENCODES a protein that exhibits ionotropic glutamate receptor binding; INVOLVED IN maintenance of protein location; positive regulation of mini excitatory postsynaptic potential; regulation of postsynaptic membrane neurotransmitter receptor levels; FOUND IN excitatory synapse; glutamatergic synapse; postsynaptic density; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 11 | 75238706 | 75389748 | Rat | 132 | symbol , PANTHER , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359383 | Rassf1 | Ras association domain family member 1 | ENCODES a protein that exhibits identical protein binding (ortholog); small GTPase binding (ortholog); INVOLVED IN DNA damage response (ortholog); positive regulation of protein ubiquitination (ortholog); protein stabilization (ortholog); PARTICIPATES IN p53 signaling pathway; non-small cell lung ca rcinoma pathway; urinary bladder cancer pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Animal Mammary Neoplasms (ortholog); bladder disease (ortholog); FOUND IN microtubule cytoskeleton (ortholog); nucleus (ortholog); INTERACTS WITH (S)-colchicine; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 17beta-estradiol | 8 | 117103665 | 117114805 | Rat | 232 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309652 | Tm4sf1 | transmembrane 4 L six family member 1 | INVOLVED IN blastocyst formation (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 2 | 143606980 | 143616176 | Rat | 178 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307978 | Tm6sf1 | transmembrane 6 superfamily member 1 | ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN lysosomal membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 1 | 145209052 | 145237725 | Rat | 77 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1307085 | Tm9sf1 | transmembrane 9 superfamily member 1 | INVOLVED IN autophagy (inferred); FOUND IN autophagosome membrane (inferred); cytoplasmic vesicle (inferred); lysosomal membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A | 15 | 33097541 | 33108106 | Rat | 54 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1309847 | Rassf10 | Ras association domain family member 10 | INVOLVED IN positive regulation of neural precursor cell proliferation (ortholog); positive regulation of neurogenesis (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH alpha-Zearalanol; cisplatin; Cuprizon | 1 | 176492814 | 176498127 | Rat | 47 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1305871 | Tnfsf13 | TNF superfamily member 13 | ENCODES a protein that exhibits cytokine activity (inferred); tumor necrosis factor receptor binding (inferred); INVOLVED IN immunoglobulin mediated immune response (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of germinal center formation (ortholog ); PARTICIPATES IN adaptive immune response pathway; cytokine mediated signaling pathway; rheumatoid arthritis pathway; ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); B-lymphoblastic leukemia/lymphoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); external side of plasma membrane (ortholog); INTERACTS WITH (+)-pilocarpine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 54898805 | 54901815 | Rat | 126 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1305066 | Tnfsf18 | TNF superfamily member 18 | ENCODES a protein that exhibits identical protein binding (ortholog); tumor necrosis factor receptor superfamily binding (ortholog); INVOLVED IN activated CD4-positive, alpha-beta T cell proliferation (ortholog); negative regulation of T-helper 17 cell lineage commitment (ortholog); obsolete positiv e regulation of NF-kappaB transcription factor activity (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; FOUND IN cell surface (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; endosulfan | 13 | 76366790 | 76440673 | Rat | 77 | symbol , PANTHER , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1310115 | Tnfrsf14 | TNF receptor superfamily member 14 | ENCODES a protein that exhibits cytokine binding (ortholog); receptor ligand activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN defense response to Gram-negative bacterium (ortholog); defense response to Gram-positive bacterium (ortholog); negative regulation of adaptive i mmune memory response (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH myocardial infarction; arteriosclerosis (ortholog); Brain Injuries (ortholog); FOUND IN external side of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,2',4,4'-Tetrabromodiphenyl ether | 5 | 170768413 | 170776749 | Rat | 115 | symbol , PANTHER , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1565872 | Tnfrsf18 | TNF receptor superfamily member 18 | ENCODES a protein that exhibits tumor necrosis factor receptor activity (inferred); INVOLVED IN positive regulation of cell adhesion (ortholog); positive regulation of leukocyte migration (ortholog); positive regulation of tyrosine phosphorylation of STAT protein (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH anogenital venereal wart (ortholog); HTLV-1-associated myelopathy/tropical spastic paraparesis (ortholog); leishmaniasis (ortholog); FOUND IN external side of plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 171901734 | 171904578 | Rat | 83 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1564996 | Tnfrsf19 | TNF receptor superfamily member 19 | ENCODES a protein that exhibits signaling receptor activity (inferred); INVOLVED IN hair follicle development (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH melanoma (ortholog); Nasopharyngea l Neoplasms (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 15 | 39268305 | 39334566 | Rat | 178 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 621237 | Tnfrsf1a | TNF receptor superfamily member 1A | ENCODES a protein that exhibits protease binding; protein-containing complex binding; tumor necrosis factor binding; INVOLVED IN cellular response to estradiol stimulus; negative regulation of apoptotic process; negative regulation of gene expression; PARTICIPATES IN tumor necrosis factor mediated s ignaling pathway; ceramide signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH Acute Experimental Pancreatitis; Brain Injuries; brain ischemia; FOUND IN axon; cell surface; extracellular space; INTERACTS WITH (+)-pilocarpine; (S)-nicotine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | 4 | 159837119 | 159849817 | Rat | 667 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621238 | Tnfrsf1b | TNF receptor superfamily member 1B | ENCODES a protein that exhibits tumor necrosis factor receptor activity; tumor necrosis factor binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN cellular response to growth factor stimulus; cellular response to tumor necrosis factor; immune response; PARTICIPATES IN tumor necrosis factor mediated signaling pathway; amyotrophic lateral sclerosis pathway; cytokine mediated signaling pathway; ASSOCIATED WITH Acute Experimental Pancreatitis; Crohn's disease; Experimental Arthritis; FOUND IN axon; neuronal cell body; perinuclear region of cytoplasm; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 17beta-estradiol | 5 | 162356250 | 162387411 | Rat | 376 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308041 | Tnfrsf10b | TNF receptor superfamily member 10b | ENCODES a protein that exhibits identical protein binding (ortholog); protease binding (ortholog); INVOLVED IN extrinsic apoptotic signaling pathway via death domain receptors; male gonad development; cellular response to mechanical stimulus (ortholog); PARTICIPATES IN Trail mediated signaling pathw ay; apoptotic cell death pathway; influenza A pathway; ASSOCIATED WITH Burns; colon cancer; osteoarthritis; FOUND IN cell surface (ortholog); cytosol (ortholog); Golgi apparatus (ortholog); INTERACTS WITH bisphenol A; (-)-epigallocatechin 3-gallate (ortholog); 1-fluoro-2,4-dinitrobenzene (ortholog) | 15 | 51249883 | 51278091 | Rat | 255 | symbol , PANTHER , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1563614 | Tnfrsf11a | TNF receptor superfamily member 11A | ENCODES a protein that exhibits cytokine binding (ortholog); transmembrane signaling receptor activity (ortholog); tumor necrosis factor receptor activity (ortholog); INVOLVED IN cellular response to zinc ion starvation; osteoclast differentiation; response to ethanol; PARTICIPATES IN cytokine media ted signaling pathway; rheumatoid arthritis pathway; ASSOCIATED WITH Alveolar Bone Loss; myocarditis; Tibial Fractures; FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); membrane raft (ortholog); INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 13 | 22442930 | 22501257 | Rat | 222 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1305381 | Relt | RELT, TNF receptor | INVOLVED IN amelogenesis (ortholog); apoptotic process (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta type 3C (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 17beta-estra diol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 164619059 | 164636707 | Rat | 82 | PANTHER , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1310626 | Zcchc2 | zinc finger CCHC-type containing 2 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); phosphatidylinositol binding (inferred); ASSOCIATED WITH bipolar disorder (ortholog); Human Influenza (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 13 | 22621275 | 22708232 | Rat | 93 | PANTHER , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1566298 | Asb11 | ankyrin repeat and SOCS box containing 11 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); protein K11-linked ubiquitination (ortholog); FOUND IN Cu l5-RING ubiquitin ligase complex (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH alpha-Zearalanol; bisphenol A; flutamide | X | 33646389 | 33669790 | Rat | 49 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305298 | 1700001K19Rikl | RIKEN cDNA 1700001K19 gene like | INTERACTS WITH 4,4'-sulfonyldiphenol; bis(2-ethylhexyl) phthalate; bisphenol A | 6 | 135502831 | 135523451 | Rat | 7 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308065 | 2610318N02Rikl | RIKEN cDNA 2610318N02 gene like | INTERACTS WITH acrylamide; bisphenol A; copper atom | 11 | 97383363 | 97400092 | Rat | 6 | PANTHER | gene, protein-coding, PREDICTED [RefSeq] |
| 1304624 | 2700097O09Rikl | RIKEN cDNA 2700097009 gene like | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; endosulfan; gentamycin | 6 | 78277757 | 78322329 | Rat | 8 | PANTHER | gene, protein-coding, PREDICTED [RefSeq] |
| 1307525 | 9330159F19Rikl | RIKEN cDNA 9330159F19 gene like | INTERACTS WITH bisphenol A; fenvalerate; titanium dioxide | 1 | 30444202 | 30469195 | Rat | 21 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311135 | Aasdh | aminoadipate-semialdehyde dehydrogenase | ENCODES a protein that exhibits ATP binding (inferred); ligase activity (inferred); nucleotide binding (inferred); INVOLVED IN amino acid activation for nonribosomal peptide biosynthetic process (ortholog); beta-alanine metabolic process (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-t etrachlorodibenzodioxine; 6-propyl-2-thiouracil | 14 | 31609488 | 31636066 | Rat | 56 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311222 | Abcb10 | ATP binding cassette subfamily B member 10 | ENCODES a protein that exhibits ABC-type transporter activity (ortholog); ATP binding (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN erythrocyte development (ortholog); export from the mitochondrion (ortholog); heme biosynthetic process (ortholog); ASSOCIATED WITH Colorectal Neoplasms ( ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH acetamide; aflatoxin B1; bisphenol A | 19 | 68850108 | 68881689 | Rat | 122 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309721 | Abhd14a | abhydrolase domain containing 14A | ENCODES a protein that exhibits hydrolase activity (inferred); FOUND IN cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 115957853 | 115965697 | Rat | 78 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308918 | Abraxas2 | abraxas 2, BRISC complex subunit | ENCODES a protein that exhibits microtubule binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN attachment of spindle microtubules to kinetochore (ortholog); cellular response to freezing (ortholog); chromosome segregation (ortholog); FOUND IN BRISC compl ex (ortholog); centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 1 | 197077177 | 197102753 | Rat | 95 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308647 | Abtb3 | ankyrin repeat and BTB domain containing 3 | ENCODES a protein that exhibits PDZ domain binding (ortholog); INVOLVED IN exploration behavior (ortholog); protein stabilization (ortholog); synaptic transmission, glutamatergic (ortholog); ASSOCIATED WITH Liver Neoplasms (ortholog); prostate cancer (ortholog); FOUND IN glutamatergic synapse (ortho log); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; all-trans-retinoic acid | 7 | 19922883 | 20199740 | Rat | 112 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304629 | Acer2 | alkaline ceramidase 2 | ENCODES a protein that exhibits N-acylsphingosine amidohydrolase activity (ortholog); INVOLVED IN cellular response to xenobiotic stimulus (ortholog); ceramide catabolic process (ortholog); DNA damage response (ortholog); PARTICIPATES IN sphingolipid metabolic pathway; FOUND IN Golgi apparatus (orth olog); Golgi membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 106437773 | 106488572 | Rat | 143 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311945 | Acin1 | apoptotic chromatin condensation inducer 1 | ENCODES a protein that exhibits nucleic acid binding (inferred); INVOLVED IN apoptotic chromosome condensation (ortholog); erythrocyte differentiation (ortholog); negative regulation of mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN mRNA decay pathway; RNA transport pathway; spliceosome pathway; FOUND IN ASAP complex (ortholog); exon-exon junction complex (ortholog); nuclear speck (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 15 | 32072121 | 32117004 | Rat | 141 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306513 | Acot13 | acyl-CoA thioesterase 13 | ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); protein homotetramerization (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta -estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 17 | 40668404 | 40680876 | Rat | 124 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311058 | Adck2 | aarF domain containing kinase 2 | INVOLVED IN regulation of ubiquinone biosynthetic process (ortholog); ASSOCIATED WITH mitochondrial myopathy (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH bisphenol A; gentamycin; ketamine | 4 | 69315633 | 69328535 | Rat | 68 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307217 | Adgrg7 | adhesion G protein-coupled receptor G7 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN cell surface receptor signaling pathway (inferred); G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); ASSOCIATED WI TH hepatocellular carcinoma (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; alpha-Zearalanol | 11 | 57282904 | 57345417 | Rat | 45 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309906 | Adprm | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | ENCODES a protein that exhibits ADP-ribose diphosphatase activity (inferred); CDP-glycerol diphosphatase activity (inferred); hydrolase activity (inferred); INTERACTS WITH bisphenol A; flutamide; leflunomide | 10 | 52231085 | 52243637 | Rat | 55 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307617 | Adsl | adenylosuccinate lyase | ENCODES a protein that exhibits (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity; identical protein binding; N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; INVOLVED IN aerobic respiration; AMP biosynthetic process; response to hypoxia; PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH breast cancer; Experimental Diabetes Mellitus; Experimental Liver Neoplasms; FOUND IN cytosol (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 7 | 114359440 | 114383618 | Rat | 166 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307233 | Aebp2 | AE binding protein 2 | ENCODES a protein that exhibits transcription coregulator activity (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH Hirschsprung's disease (ortholog); Waardenburg syndrome (ortholog); FOUND IN ESC/E(Z) complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',5,5'-tetrabromobisphenol A | 4 | 175258286 | 175297149 | Rat | 95 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311580 | Afap1l1 | actin filament associated protein 1-like 1 | ASSOCIATED WITH neuromuscular disease (ortholog); FOUND IN cell projection (inferred); cytoplasm (inferred); podosome (inferred); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 18 | 57454120 | 57514584 | Rat | 84 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309244 | Agap1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | ENCODES a protein that exhibits phospholipid binding (ortholog); INVOLVED IN regulation of modification of postsynaptic structure; PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH autistic disorder (ortholog); COVID-19 (ortholog); FOUND IN postsynaptic endosome; INTERACTS WITH 2,3,7,8-tetrachlor odibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide | 9 | 97487382 | 97922870 | Rat | 127 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1312038 | Agmo | alkylglycerol monooxygenase | ENCODES a protein that exhibits glyceryl-ether monooxygenase activity (ortholog); iron ion binding (ortholog); INVOLVED IN ether lipid metabolic process (ortholog); membrane lipid metabolic process (ortholog); triglyceride biosynthetic process (ortholog); FOUND IN endoplasmic reticulum (ortholog); e ndoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; alpha-Zearalanol | 6 | 59713495 | 60044851 | Rat | 100 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304606 | Agr2 | anterior gradient 2, protein disulphide isomerase family member | ENCODES a protein that exhibits dystroglycan binding (ortholog); epidermal growth factor receptor binding (ortholog); identical protein binding (ortholog); INVOLVED IN cell chemotaxis (ortholog); digestive tract morphogenesis (ortholog); endoplasmic reticulum unfolded protein response (ortholog); AS SOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); pancreatic ductal adenocarcinoma (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular region (ortholog); extracellular space (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 3,3',5,5'-tetrabromobisphenol A | 6 | 58435908 | 58456678 | Rat | 169 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310031 | Ahdc1 | AT hook, DNA binding motif, containing 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); promoter-enhancer loop anchoring activity (ortholog); INVOLVED IN adipose tissue development (ortholog); aerobic respiration (ortholog); energy reserve metabolic process (ortholog); ASSOCIATED WITH abdominal obesit y-metabolic syndrome 3 (ortholog); autism spectrum disorder (ortholog); cerebellar hypoplasia (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 5 | 150512182 | 150578804 | Rat | 99 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303040 | Ahi1 | Abelson helper integration site 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN embryonic brain development; negative regulation of D-glucose import across plasma membrane; response to food; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); cerebellar disease (orth olog); FOUND IN adherens junction (ortholog); cell-cell junction (ortholog); centriole (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3,3',5,5'-tetrabromobisphenol A | 1 | 17580859 | 17711775 | Rat | 203 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311139 | Aire | autoimmune regulator | ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); identical protein binding (ortholog); INVOLVED IN central tolerance induction to self antigen (ortholog); humoral immune response (ortholog); negative thymic T cell selection (ortholog); PARTICIPATES IN primary immunodeficiency pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH abnormal NK cell number; abnormal thymus morphology; alopecia; ASSOCIATED WITH autoimmune polyendocrine syndrome; autoimmune polyendocrine syndrome type 1 (ortholog); candidiasis (ortholog); FOUND IN cytoplasm (ortholog); nuclear body (ortholog); nucleus (ortholog); INTERACTS WITH acrylamide; bisphenol A; cadmium dichloride | 20 | 10635775 | 10650709 | Rat | 129 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308869 | Akap10 | A-kinase anchoring protein 10 | ENCODES a protein that exhibits protein kinase A binding (ortholog); INVOLVED IN intracellular protein localization (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; ASSOCIATED WITH Heart Block (ortholog); sudden infant death syndrome (ortholog); FOUND IN cytosol (ortholog); mito chondrion (ortholog); protein-containing complex (ortholog); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 10 | 47044819 | 47108153 | Rat | 88 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308614 | Aldh7a1 | aldehyde dehydrogenase 7 family, member A1 | ENCODES a protein that exhibits aldehyde dehydrogenase (NAD+) activity (ortholog); betaine-aldehyde dehydrogenase (NAD+) activity (ortholog); identical protein binding (ortholog); INVOLVED IN endosome to lysosome transport (ortholog); energy homeostasis (ortholog); Golgi to endosome transport (ortho log); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; choline metabolic pathway; glutaric aciduria type I pathway; ASSOCIATED WITH benign neonatal seizures (ortholog); bone disease (ortholog); coloboma (ortholog); FOUND IN cytosol (ortholog); Golgi membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 18 | 52208035 | 52240293 | Rat | 289 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304826 | Alg12 | ALG12, alpha-1,6-mannosyltransferase | ENCODES a protein that exhibits dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity (ortholog); INVOLVED IN dolichol-linked oligosaccharide biosynthetic process (ortholog); protein N-linked glycosylation (ortholog); PARTICIPATES IN N-linked glycan biosynthetic pathway; ASSOCIATED WITH congenital disorder of glycosylation (ortholog); congenital disorder of glycosylation Ig (ortholog); Desbuquois dysplasia (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 7 | 121774796 | 121789175 | Rat | 81 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309940 | Alg2 | ALG2, alpha-1,3/1,6-mannosyltransferase | ENCODES a protein that exhibits alpha-1,3-mannosyltransferase activity (ortholog); GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity (ortholog); GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity (ortholog); INVOLVED IN dolichol-linked oligosaccharide biosynthe tic process (ortholog); glycoprotein biosynthetic process (ortholog); protein N-linked glycosylation (ortholog); PARTICIPATES IN N-linked glycan biosynthetic pathway; ASSOCIATED WITH congenital disorder of glycosylation (ortholog); congenital disorder of glycosylation Ii (ortholog); congenital disorder of glycosylation type II (ortholog); FOUND IN cytoplasmic side of endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 5 | 66564328 | 66568887 | Rat | 125 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308815 | Alg6 | ALG6, alpha-1,3-glucosyltransferase | ENCODES a protein that exhibits dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity (ortholog); glucosyltransferase activity (ortholog); INVOLVED IN dolichol-linked oligosaccharide biosynthetic process (ortholog); protein N-linked glycosylation (ortholog); PARTICIPATES IN N-lin ked glycan biosynthetic pathway; ASSOCIATED WITH congenital disorder of glycosylation (ortholog); congenital disorder of glycosylation Ic (ortholog); cystic kidney disease (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; bisphenol A | 5 | 119520415 | 119606365 | Rat | 86 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306377 | Alkbh2 | alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase | ENCODES a protein that exhibits 2-oxoglutarate-dependent dioxygenase activity (ortholog); broad specificity oxidative DNA demethylase activity (ortholog); cytosine C-5 DNA demethylase activity (ortholog); INVOLVED IN DNA alkylation repair (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortho log); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 12 | 48156825 | 48161489 | Rat | 93 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304613 | Alpk1 | alpha-kinase 1 | ENCODES a protein that exhibits monosaccharide binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cilium assembly (ortholog); cytoplasmic pattern recognition receptor signaling pathway (ortholog); innate immune response (ortholog); ASSOCIATED WITH diabetes mellitus (ortholog); Diabetic Nephropathies (ortholog); genetic disease (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); cilium (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil | 2 | 218801425 | 218924013 | Rat | 126 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309860 | Alpk3 | alpha-kinase 3 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); protein serine/threonine kinase activity (inferred); INVOLVED IN cardiac muscle cell development (ortholog); cardiac muscle cell differentiation (ortholog); heart development (ortholog); ASSOCIATED WITH cardiomyopath y (ortholog); cardiovascular system disease (ortholog); Dilated Cardiomyopathy with Left Ventricular Noncompaction (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 1 | 144423690 | 144471534 | Rat | 92 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305208 | Als2cl | ALS2 C-terminal like | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN intracellular protein localization (ortholog); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN cytoplasmic vesicle (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; bromobenzene | 8 | 119746498 | 119762824 | Rat | 98 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1308879 | Amdhd1 | amidohydrolase domain containing 1 | ENCODES a protein that exhibits hydrolase activity (inferred); hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (inferred); hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides (inferred); INVOLVED IN L-histidine catabolic process to glutamate and formamide (inferred); L-histidine catabolic process to glutamate and formate (inferred); L-histidine metabolic process (inferred); PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; FOUND IN cytoplasm (inferred); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 7 | 29930966 | 29946199 | Rat | 103 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303079 | Amigo1 | adhesion molecule with Ig like domain 1 | ENCODES a protein that exhibits potassium channel regulator activity (ortholog); INVOLVED IN axonal fasciculation; axonogenesis; cellular response to L-glutamate; ASSOCIATED WITH schizophrenia (ortholog); FOUND IN neuronal cell body; pericellular basket; dendrite (ortholog); INTERACTS WITH 1-naphthy l isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 198511285 | 198516744 | Rat | 113 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307915 | Ammecr1l | AMMECR1 like | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; bisphenol A | 18 | 23661649 | 23685391 | Rat | 65 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305546 | Anapc2 | anaphase promoting complex subunit 2 | INVOLVED IN negative regulation of gene expression; positive regulation of axon extension; positive regulation of dendrite morphogenesis; PARTICIPATES IN cell cycle pathway, mitotic; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); aplastic anemia (ortholo g); Fetal Growth Retardation (ortholog); FOUND IN anaphase-promoting complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A | 3 | 28484590 | 28496338 | Rat | 88 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304809 | Ankef1 | ankyrin repeat and EF-hand domain containing 1 | ASSOCIATED WITH congenital myasthenic syndrome 18 (ortholog); developmental and epileptic encephalopathy 12 (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-Tetrachlorodibenzofuran; acetamide | 3 | 144300500 | 144335759 | Rat | 54 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308184 | Ankle1 | ankyrin repeat and LEM domain containing 1 | ENCODES a protein that exhibits cobalt ion binding (ortholog); DNA endonuclease activity (ortholog); endonuclease activity (ortholog); INVOLVED IN determination of adult lifespan (ortholog); DNA damage response (ortholog); DNA repair (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cytoplas m (ortholog); cytosol (ortholog); midbody (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; bromobenzene | 16 | 18109865 | 18116999 | Rat | 87 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307862 | Ankrd22 | ankyrin repeat domain 22 | INVOLVED IN calcium ion import (ortholog); cell population proliferation (ortholog); immune response (ortholog); INTERACTS WITH acrylamide; aflatoxin B1; atrazine | 1 | 241052235 | 241083737 | Rat | 72 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 11508551 | Anp32a | acidic nuclear phosphoprotein 32 family member A | ENCODES a protein that exhibits cell adhesion molecule binding; integrin binding; INVOLVED IN negative regulation of plasma membrane bounded cell projection assembly; negative regulation of protein modification process; nucleocytoplasmic transport (ortholog); PARTICIPATES IN CRM1 export pathway; ASS OCIATED WITH Brain Injuries; Acute Liver Failure (ortholog); Animal Disease Models (ortholog); FOUND IN chromatin; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1-bromopropane; 17beta-estradiol | 8 | 71724578 | 71760922 | Rat | 189 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309592 | Aopep | aminopeptidase O | ENCODES a protein that exhibits aminopeptidase activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH atrial fibrillation (ortholog); breast cancer (ortholog); dystonia 31 (ortholog); FOUND IN nucleolus (ortholog); INTERA CTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl | 17 | 1817001 | 2133008 | Rat | 137 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311435 | Ap1ar | adaptor-related protein complex 1 associated regulatory protein | ENCODES a protein that exhibits AP-1 adaptor complex binding (ortholog); kinesin binding (ortholog); INVOLVED IN intracellular protein localization (ortholog); negative regulation of cell motility (ortholog); negative regulation of receptor recycling (ortholog); FOUND IN endosome (ortholog); Golgi a pparatus (ortholog); transport vesicle (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cocaine | 2 | 218951104 | 218983495 | Rat | 74 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303123 | Apold1 | apolipoprotein L domain containing 1 | ENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN angiogenesis; endothelial cell activation; regulation of endothelial cell differentiation; ASSOCIATED WITH Bleeding Disorder, Vascular-Type (ortholog); FOUND IN cell-cell junction (ortholog); nucleoplasm (ortholog); plasma membran e (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 4 | 169499728 | 169557075 | Rat | 128 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311384 | Apon | apolipoprotein N | INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 7 | 1271514 | 1272917 | Rat | 25 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306488 | Appbp2 | amyloid beta precursor protein binding protein 2 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN negative regulation of beige fat cell differentiation (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ubiquitin-dependent protein catabolic process via t he C-end degron rule pathway (ortholog); FOUND IN Cul2-RING ubiquitin ligase complex (ortholog); cytoplasmic vesicle membrane (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 70555212 | 70597267 | Rat | 110 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306452 | Arap2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | ENCODES a protein that exhibits phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); INVOLVED IN signal transduction (inferred); PARTICIPATES IN endocytosis pathway; FOUND IN cytoplasm (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol | 14 | 50921323 | 51120972 | Rat | 139 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310061 | Arglu1 | arginine and glutamate rich 1 | ENCODES a protein that exhibits pre-mRNA binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN regulation of alternative mRNA splicing, via spliceosome (ortholog); FOUND IN nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlor odibenzodioxine; 4,4'-sulfonyldiphenol | 16 | 87455097 | 87479148 | Rat | 125 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308738 | Arhgap35 | Rho GTPase activating protein 35 | ENCODES a protein that exhibits GTPase activating protein binding; GTPase activator activity; protein-containing complex binding; INVOLVED IN positive regulation of GTPase activity; axon guidance (ortholog); axonal fasciculation (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional sign aling axis; platelet-derived growth factor signaling pathway; ASSOCIATED WITH Anophthalmia (ortholog); lung adenocarcinoma (ortholog); Martsolf syndrome 1 (ortholog); FOUND IN actin cytoskeleton (ortholog); ciliary basal body (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 1 | 86330566 | 86447414 | Rat | 173 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311448 | Arhgef18 | Rho/Rac guanine nucleotide exchange factor 18 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); negative regulation of stress fiber assembly (ortholog); protein localization to cell-cell junction (ortholog); ASSOCIATED WITH fundus dystrophy (ortholog); genetic disease (ortholog); optic atrophy (ortholog); FOUND IN apical part of cell (ortholog); cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol | 12 | 6192958 | 6300997 | Rat | 103 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310376 | Arhgef39 | Rho guanine nucleotide exchange factor 39 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN positive regulation of cell migration (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2- thiouracil; acetamide | 5 | 62548300 | 62551870 | Rat | 89 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305299 | Arid3a | AT-rich interaction domain 3A | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); identical protein binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); membrane raft (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 7 | 10403161 | 10431551 | Rat | 126 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303298 | Arl10 | ARF like GTPase 10 | ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); metal ion binding (inferred); FOUND IN mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 17 | 10035320 | 10043732 | Rat | 67 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311463 | Arl14ep | ARF like GTPase 14 effector protein | ASSOCIATED WITH Developmental Disabilities (ortholog); intellectual disability (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH bisphenol A; gentamycin; methamphetamine | 3 | 113896731 | 113908994 | Rat | 43 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306008 | Armc12 | armadillo repeat containing 12 | INVOLVED IN flagellated sperm motility (ortholog); positive regulation of cell growth (ortholog); sperm mitochondrial sheath assembly (ortholog); ASSOCIATED WITH prostate cancer (ortholog); spermatogenic failure 90 (ortholog); FOUND IN mitochondrial outer membrane (ortholog); mitochondrion (ortholog ); nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; cadmium dichloride | 20 | 6589573 | 6600059 | Rat | 43 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310043 | Armc7 | armadillo repeat containing 7 | FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 10 | 101222056 | 101238598 | Rat | 48 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311021 | Arpin | actin-related protein 2/3 complex inhibitor | INVOLVED IN actin filament bundle assembly (ortholog); blood vessel development (ortholog); directional locomotion (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); COVID-19 (ortholog); FOUND IN lamellipodium (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-te trachlorodibenzodioxine | 1 | 143273590 | 143282426 | Rat | 65 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310182 | Arsk | arylsulfatase family, member K | ENCODES a protein that exhibits arylsulfatase activity (ortholog); glucuronate-2-sulfatase activity (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); mucopolysaccharidosis (ortholog); mucopolysaccharidosis X (ortholog); FOUND IN extracellular region (ortholog); lysosome (ortholog); IN TERACTS WITH atrazine; bisphenol A; gentamycin | 2 | 7306181 | 7363311 | Rat | 68 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306456 | Art4 | ADP-ribosyltransferase 4 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); NAD+-protein-arginine ADP-ribosyltransferase activity (inferred); nucleotidyltransferase activity (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide | 4 | 171468415 | 171482435 | Rat | 79 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359255 | Ascc1 | activating signal cointegrator 1 complex subunit 1 | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN regulation of DNA-templated transcription (ortholog); PARTICIPATES IN estrogen signaling pathway; ASSOCIATED WITH Barrett's esophagus (ortholog); centronuclear myopathy (ortholog); fetal akinesia def ormation sequence syndrome 1 (ortholog); FOUND IN nucleus (ortholog); transcription regulator complex (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; PCB138 | 20 | 28484044 | 28574195 | Rat | 66 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306350 | Ash1l | ASH1 like histone lysine methyltransferase | ENCODES a protein that exhibits histone H3K36 methyltransferase activity (ortholog); histone H3K4 methyltransferase activity (ortholog); histone H3K9 methyltransferase activity (ortholog); INVOLVED IN decidualization (ortholog); flagellated sperm motility (ortholog); negative regulation of acute inf lammatory response (ortholog); PARTICIPATES IN histone modification pathway; lysine degradation pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal dominant intellectual developmental disorder 52 (ortholog); Developmental Disabilities (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 2 | 176644393 | 176780848 | Rat | 153 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306332 | Asnsd1 | asparagine synthetase domain containing 1 | INVOLVED IN adipose tissue development (ortholog); muscle organ development (ortholog); skeletal muscle organ development (ortholog); ASSOCIATED WITH myopathy (ortholog); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; bisphenol A | 9 | 55618799 | 55631064 | Rat | 64 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306636 | Asphd1 | aspartate beta-hydroxylase domain containing 1 | ENCODES a protein that exhibits dioxygenase activity (inferred); oxidoreductase activity (inferred); ASSOCIATED WITH spondylocostal dysostosis 5 (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; acrylamide | 1 | 190983506 | 190987440 | Rat | 51 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307111 | Aspm | assembly factor for spindle microtubules | ENCODES a protein that exhibits calmodulin binding (ortholog); INVOLVED IN brain development (ortholog); cerebral cortex development (ortholog); developmental growth (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); COVID-19 (ortholog); fetal akinesia deformation sequence syndrome 1 ( ortholog); FOUND IN apical plasma membrane; centrosome; midbody; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 13 | 53625584 | 53674489 | Rat | 274 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304643 | Aste1 | asteroid structure-specific endonuclease 1 | ENCODES a protein that exhibits 3' overhang single-stranded DNA endodeoxyribonuclease activity (ortholog); single-stranded DNA endodeoxyribonuclease activity (ortholog); INVOLVED IN double-strand break repair via homologous recombination (ortholog); double-strand break repair via nonhomologous end j oining (ortholog); ASSOCIATED WITH Lynch syndrome (ortholog); mismatch repair cancer syndrome (ortholog); INTERACTS WITH 17beta-estradiol; benzo[a]pyrene; bisphenol A | 8 | 114905349 | 114923775 | Rat | 48 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309335 | Ate1 | arginyltransferase 1 | ENCODES a protein that exhibits arginyl-tRNA--protein transferase activity (ortholog); INVOLVED IN proteasomal protein catabolic process (ortholog); protein arginylation (ortholog); response to oxidative stress (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); IN TERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 194391843 | 194514284 | Rat | 110 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305471 | Atf6 | activating transcription factor 6 | ENCODES a protein that exhibits ubiquitin protein ligase binding; DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN eye development (ortholog); positive regulation of apoptotic process (ortholog); po sitive regulation of ATF6-mediated unfolded protein response (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; Alzheimer's disease pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH borna disease; Temporomandibular Joint Osteoarthritis; achromatopsia (ortholog); FOUND IN nucleus; endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH (+)-schisandrin B; (S)-nicotine; 1,2-dimethylhydrazine | 13 | 85460312 | 85639959 | Rat | 589 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305781 | Atmin | ATM interactor | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); dynein complex binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN motile cilium assembly (ortholog); positive regulation of DNA-templated transcri ption (ortholog); positive regulation of gene expression (ortholog); FOUND IN nuclear body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride | 19 | 61905343 | 61922443 | Rat | 83 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306927 | Atp13a4 | ATPase 13A4 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATPase-coupled monoatomic cation transmembrane transporter activity (inferred); INVOLVED IN intracellular calcium ion homeostasis (ortholog); ASSOCIATED WITH congenital myopathy 1A (ortholog); FOUND IN early endosome membrane (ortholog); endoplasmic reticulum membrane (ortholog); late endosome membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 11 | 84727014 | 84864747 | Rat | 91 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310619 | Atp6v1b1 | ATPase H+ transporting V1 subunit B1 | ENCODES a protein that exhibits protein-containing complex binding; proton transmembrane transporter activity (ortholog); INVOLVED IN adult behavior (ortholog); ATP metabolic process (ortholog); calcium ion homeostasis (ortholog); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathw ay; rheumatoid arthritis pathway; ASSOCIATED WITH autosomal recessive distal renal tubular acidosis 3 with or without sensorineural hearing loss (ortholog); autosomal recessive nonsyndromic deafness (ortholog); Distal Renal Tubular Acidosis (ortholog); FOUND IN apical plasma membrane; basolateral plasma membrane; extrinsic component of synaptic vesicle membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol | 4 | 117781444 | 117800103 | Rat | 168 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311605 | Atraid | all-trans retinoic acid-induced differentiation factor | ENCODES a protein that exhibits xenobiotic transmembrane transporter activity (ortholog); INVOLVED IN cell differentiation (ortholog); negative regulation of osteoblast proliferation (ortholog); negative regulation of protein catabolic process (ortholog); FOUND IN lysosomal membrane (ortholog); nucl ear envelope (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 3-chloropropane-1,2-diol; acrylamide | 6 | 31035194 | 31039779 | Rat | 66 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311493 | Atxn7l3 | ataxin 7-like 3 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH h ereditary breast ovarian cancer syndrome (ortholog); FOUND IN DUBm complex (ortholog); nucleus (ortholog); SAGA complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin | 10 | 87742993 | 87750247 | Rat | 73 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309541 | B4gat1 | beta-1,4-glucuronyltransferase 1 | ENCODES a protein that exhibits glucuronosyltransferase activity (ortholog); N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity (ortholog); INVOLVED IN axon guidance (ortholog); glycoprotein biosynthetic process (ortholog); poly-N-acetyllactosamine biosynthetic process (ortholog ); PARTICIPATES IN keratan sulfate biosynthetic pathway; lacto-series glycosphingolipid metabolic pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); congenital muscular dystrophy-dystroglycanopathy type A1 (ortholog); congenital muscular dystrophy-dystroglycanopathy type A13 (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A | 1 | 211772644 | 211774866 | Rat | 99 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305522 | B9d1 | B9 domain containing 1 | ENCODES a protein that exhibits hedgehog receptor activity (ortholog); INVOLVED IN camera-type eye development (ortholog); cilium assembly (ortholog); embryonic digit morphogenesis (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); ciliopathy (ortholog); Experimental Liver Cirrh osis (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); ciliary transition zone (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane; 4,4'-sulfonyldiphenol | 10 | 46685410 | 46698580 | Rat | 132 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306693 | Bach1 | BACH transcriptional regulator 1 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN DNA repair (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Cardiotoxicity (ortholog); Fibrosis (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 4-amino-2,6-dinitrotoluene; bisphenol A | 11 | 40425721 | 40461118 | Rat | 227 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 10059729 | Baiap3 | BAI1-associated protein 3 | ENCODES a protein that exhibits calcium ion binding (ortholog); phospholipid binding (ortholog); SNARE binding (ortholog); INVOLVED IN dense core granule maturation (ortholog); G protein-coupled receptor signaling pathway (ortholog); modulation of chemical synaptic transmission (ortholog); ASSOCIATE D WITH long QT syndrome (ortholog); FOUND IN cytosol (ortholog); dense core granule (ortholog); early endosome membrane (ortholog); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; amphetamine | 10 | 14764768 | 14777516 | Rat | 93 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306199 | Baz1a | bromodomain adjacent to zinc finger domain, 1A | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN chromatin remodeling (ortholog); DNA-templated DNA replication (ortholog); nucleosome assembly (ortholog); PARTICIPATES IN ISWI family mediated chromatin remodeling pathway; ASSOCIATED WITH X-linke d VACTERL association (ortholog); FOUND IN CHRAC (ortholog); nuclear chromosome (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 6 | 78124872 | 78247672 | Rat | 152 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309801 | Baz2b | bromodomain adjacent to zinc finger domain, 2B | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleus ( ortholog); INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 3 | 64792984 | 65034547 | Rat | 108 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309134 | Bbs4 | Bardet-Biedl syndrome 4 | ENCODES a protein that exhibits alpha-tubulin binding (ortholog); beta-tubulin binding (ortholog); dynactin binding (ortholog); INVOLVED IN protein localization to centrosome; adipose tissue development (ortholog); adult behavior (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Bardet-B iedl syndrome 1 (ortholog); Bardet-Biedl syndrome 4 (ortholog); FOUND IN BBSome (ortholog); centriolar satellite (ortholog); centriole (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 8 | 68627739 | 68661232 | Rat | 199 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306433 | Bcdin3d | BCDIN3 domain containing RNA methyltransferase | ENCODES a protein that exhibits O-methyltransferase activity (ortholog); pre-miRNA binding (ortholog); RNA methyltransferase activity (ortholog); INVOLVED IN negative regulation of pre-miRNA processing (ortholog); pre-miRNA processing (ortholog); RNA methylation (ortholog); ASSOCIATED WITH Moebius s yndrome (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amitrole | 7 | 132484404 | 132488998 | Rat | 86 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310392 | Bend6 | BEN domain containing 6 | ENCODES a protein that exhibits chromatin binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN negative regulation of Notch signaling pathway (ortholog); positive regulation of neuron differentiation (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlor odibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 9 | 43576982 | 43631437 | Rat | 89 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305898 | Bend7 | BEN domain containing 7 | ENCODES a protein that exhibits DNA binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide | 17 | 78392489 | 78475459 | Rat | 68 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305377 | Best2 | bestrophin 2 | ENCODES a protein that exhibits bicarbonate channel activity (ortholog); chloride channel activity (ortholog); intracellularly ligand-gated monoatomic ion channel activity (ortholog); INVOLVED IN bicarbonate transport (ortholog); chloride transmembrane transport (ortholog); chloride transport (ortho log); FOUND IN basolateral plasma membrane (ortholog); chloride channel complex (ortholog); cilium (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bis(2-ethylhexyl) phthalate | 19 | 40047191 | 40053216 | Rat | 67 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306385 | Bicra | BRD4 interacting chromatin remodeling complex associated protein | ENCODES a protein that exhibits transcription regulator activator activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Coffin-Siris syndrome 1 (ortholog); Coffin-Siris syndrome 12 (ortholog); Developmental Disease (ortholog); FOUND IN nucleu s (ortholog); SWI/SNF complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 1 | 85790093 | 85867656 | Rat | 61 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306789 | Bin2 | bridging integrator 2 | ENCODES a protein that exhibits phospholipid binding (ortholog); INVOLVED IN cell chemotaxis (ortholog); phagocytosis, engulfment (ortholog); plasma membrane tubulation (ortholog); FOUND IN phagocytic cup (ortholog); plasma membrane (ortholog); podosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachloro dibenzodioxine; acetamide; alpha-Zearalanol | 7 | 133620782 | 133647019 | Rat | 80 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309534 | Bkgd | beta-keto-L-gulonate decarboxylase | ENCODES a protein that exhibits hydrolase activity, acting on ester bonds (ortholog); zinc ion binding (ortholog); INVOLVED IN DNA damage response (ortholog); regulation of DNA repair (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol (ortholog); 2-hydroxy propanoic acid (ortholog); 3-isobutyl-1-methyl-7H-xanthine (ortholog) | 8 | 20405240 | 20427811 | Rat | 82 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306551 | Bloc1s2 | biogenesis of lysosomal organelles complex-1, subunit 2 | ENCODES a protein that exhibits transcription factor binding; gamma-tubulin binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II; anterograde axonal transport (ortholog); anterograde synaptic vesicle transport (ortholog); ASSOCIATED WITH Sciatica; Experimental Li ver Cirrhosis (ortholog); FOUND IN centrosome; recycling endosome; BLOC-1 complex (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 252973818 | 252980873 | Rat | 137 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307100 | Bltp1 | bridge-like lipid transfer protein family member 1 | INVOLVED IN endocytic recycling (ortholog); endosomal transport (ortholog); lipid transport (ortholog); ASSOCIATED WITH Alkuraya-Kucinskas syndrome (ortholog); clubfoot (ortholog); Dandy-Walker syndrome (ortholog); FOUND IN presynapse (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estra diol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 121636181 | 121852802 | Rat | 64 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305733 | Bmerb1 | bMERB domain containing 1 | INVOLVED IN negative regulation of cell motility involved in cerebral cortex radial glia guided migration (ortholog); negative regulation of microtubule depolymerization (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Familial Thoracic Aortic Aneurysm 4 (ortholog); FOUND IN microtubule cytoskeleton (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 2286999 | 2453890 | Rat | 72 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309042 | Bnc1 | basonuclin zinc finger protein 1 | ENCODES a protein that exhibits DNA-binding transcription activator activity (ortholog); rDNA binding (ortholog); INVOLVED IN chromosome organization (ortholog); positive regulation of epithelial cell proliferation (ortholog); positive regulation of oocyte maturation (ortholog); ASSOCIATED WITH 46 X X gonadal dysgenesis (ortholog); primary ovarian insufficiency (ortholog); primary ovarian insufficiency 16 (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F | 1 | 145326881 | 145352534 | Rat | 120 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305622 | Bod1 | biorientation of chromosomes in cell division 1 | ENCODES a protein that exhibits protein phosphatase 2A binding (ortholog); protein phosphatase inhibitor activity (ortholog); INVOLVED IN mitotic metaphase chromosome alignment (ortholog); mitotic sister chromatid biorientation (ortholog); mitotic sister chromatid cohesion, centromeric (ortholog); F OUND IN centrosome (ortholog); outer kinetochore (ortholog); spindle microtubule (ortholog); INTERACTS WITH (+)-schisandrin B; bisphenol A; cadmium dichloride | 10 | 16497918 | 16504259 | Rat | 54 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305975 | Bola3 | bolA family member 3 | INVOLVED IN adaptive thermogenesis (ortholog); energy homeostasis (ortholog); glucose metabolic process (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH genetic disease (ortholog); multiple mitochondrial dysfunctions syndrome 2 (ortholog); FOU ND IN mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 4 | 117411044 | 117420491 | Rat | 97 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310866 | Bpifb2 | BPI fold containing family B, member 2 | ENCODES a protein that exhibits lipid binding (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil | 3 | 162818223 | 162837219 | Rat | 29 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309187 | Bri3 | brain protein I3 | ENCODES a protein that exhibits identical protein binding (ortholog); FOUND IN lysosomal membrane (inferred); perinuclear region of cytoplasm (inferred); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 12 | 15454673 | 15478319 | Rat | 80 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310962 | Btbd1 | BTB domain containing 1 | ENCODES a protein that exhibits cullin family protein binding (ortholog); identical protein binding (ortholog); ASSOCIATED WITH Delayed Emergence from Anesthesia (ortholog); FOUND IN cytoplasmic ribonucleoprotein granule (ortholog); cytosol (ortholog); P-body (ortholog); INTERACTS WITH 2,3,7,8-tetra chlorodibenzodioxine; aconitine; acrylamide | 1 | 145143806 | 145183653 | Rat | 55 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311454 | Btbd16 | BTB domain containing 16 | ASSOCIATED WITH prostate cancer (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil | 1 | 194765241 | 194819786 | Rat | 35 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306975 | Btbd9 | BTB domain containing 9 | INVOLVED IN adult locomotory behavior (ortholog); circadian behavior (ortholog); circadian sleep/wake cycle, non-REM sleep (ortholog); ASSOCIATED WITH intellectual disability (ortholog); restless legs syndrome (ortholog); FOUND IN glutamatergic synapse (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorod ibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene | 20 | 8287813 | 8645437 | Rat | 95 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303280 | Btla | B and T lymphocyte associated | ENCODES a protein that exhibits signaling receptor activity (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); immune response-regulating cell surface receptor signaling pathway (ortholog); negative regulation of alpha-beta T cell proliferation (ortholog); FOUND IN external side of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 11 | 69069734 | 69099331 | Rat | 73 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311343 | C10h5orf47 | similar to human chromosome 5 open reading frame 47 | INTERACTS WITH bisphenol A; cadmium dichloride; N,N-diethyl-m-toluamide | 10 | 16184999 | 16198515 | Rat | 12 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309106 | C13h1orf105 | similar to human chromosome 1 open reading frame 105 | INTERACTS WITH 17beta-estradiol; bisphenol A; gentamycin | 13 | 76846595 | 76889660 | Rat | 21 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310587 | C13h1orf115 | similar to human chromosome 1 open reading frame 115 | INVOLVED IN regulation of response to drug (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN 9+0 non-motile cilium (ortholog); INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine | 13 | 98953841 | 98963577 | Rat | 63 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308775 | C14h5orf52 | similar to human chromosome 5 open reading frame 52 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; endosulfan | 14 | 83004906 | 83013549 | Rat | 8 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308117 | C15h8orf58 | similar to human chromosome 8 open reading frame 58 | INTERACTS WITH bisphenol A; gentamycin; methamphetamine | 15 | 51638336 | 51645141 | Rat | 42 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309651 | C19h16orf74 | similar to human chromosome 16 open reading frame 74 | INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 65568997 | 65594994 | Rat | 44 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305014 | C1h10orf88 | similar to human chromosome 10 open reading frame 88 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); INTERACTS WITH bisphenol A; gentamycin; methoxychlor | 1 | 195555517 | 195580177 | Rat | 40 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307554 | C1h19orf47 | similar to human chromosome 19 open reading frame 47 | INTERACTS WITH acrylamide; bisphenol A; gentamycin | 1 | 91971879 | 92010938 | Rat | 23 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309036 | C1h19orf81 | similar to human chromosome 19 open reading frame 81 | INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amitrole | 1 | 103993832 | 104008301 | Rat | 18 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307366 | C2cd3 | C2 domain containing 3 centriole elongation regulator | INVOLVED IN brain development (ortholog); centriole elongation (ortholog); cilium assembly (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN centriolar satellite (ortholog); centriole (ortholog); ce ntrosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cocaine | 1 | 164127304 | 164225088 | Rat | 97 | PANTHER | gene, protein-coding, INFERRED [RefSeq] |
| 1306227 | C2h5orf34 | similar to human chromosome 5 open reading frame 34 | INTERACTS WITH 17beta-estradiol; acrylamide; bisphenol A | 2 | 53287353 | 53309804 | Rat | 45 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311084 | C3h9orf50 | similar to human chromosome 9 open reading frame 50 | FOUND IN cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 3 | 34477535 | 34484791 | Rat | 22 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306746 | C4h2orf42 | similar to human chromosome 2 open reading frame 42 | FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate | 4 | 120445032 | 120474227 | Rat | 49 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303027 | C5ar2 | complement C5a receptor 2 | ENCODES a protein that exhibits complement receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN negative regulation of interleukin-6 production (ortholog); negative regulation of neutrophil chemotaxis (ortholog); negative regulation of tumor necrosis factor produ ction (ortholog); FOUND IN apical part of cell (ortholog); basal plasma membrane (ortholog); INTERACTS WITH (R)-noradrenaline; 17beta-estradiol; 17beta-estradiol 3-benzoate | 1 | 86058557 | 86073583 | Rat | 101 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304567 | C5h1orf174 | similar to human chromosome 1 open reading frame 174 | ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 5 | 169798004 | 169802449 | Rat | 42 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359634 | C7h22orf23 | similar to human chromosome 22 open reading frame 23 | INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; bisphenol A | 7 | 112585341 | 112592938 | Rat | 18 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310852 | C7h8orf76 | similar to human chromosome 8 open reading frame 76 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin | 7 | 91448422 | 91459284 | Rat | 19 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308355 | C8a | complement C8 alpha chain | ENCODES a protein that exhibits complement binding; protein-containing complex binding; wide pore channel activity (ortholog); INVOLVED IN complement activation (ortholog); complement activation, GZMK pathway (ortholog); killing of cells of another organism (ortholog); PARTICIPATES IN coagulation ca scade pathway; complement system pathway; Entamoebiasis pathway; ASSOCIATED WITH myocardial infarction; meningitis (ortholog); Neisseriaceae Infections (ortholog); FOUND IN extracellular region; extracellular space; membrane attack complex (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,4-dinitrotoluene | 5 | 124812131 | 124866631 | Rat | 139 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309074 | C8g | complement C8 gamma chain | ENCODES a protein that exhibits complement binding; protein-containing complex binding; wide pore channel activity (ortholog); INVOLVED IN complement activation (ortholog); complement activation, GZMK pathway (ortholog); killing of cells of another organism (ortholog); PARTICIPATES IN coagulation ca scade pathway; complement system pathway; Entamoebiasis pathway; ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN extracellular region; extracellular space; membrane attack complex (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 28718648 | 28720232 | Rat | 113 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305464 | C8h15orf39 | similar to human chromosome 15 open reading frame 39 | INVOLVED IN negative regulation of canonical NF-kappaB signal transduction (ortholog); negative regulation of inflammatory response (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retino ic acid | 8 | 66542269 | 66551835 | Rat | 77 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309779 | C8h15orf61 | similar to human chromosome 15 open reading frame 61 | FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 8 | 72763513 | 72768248 | Rat | 39 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310553 | C9h2orf49 | similar to human chromosome 2 open reading frame 49 | INVOLVED IN embryonic morphogenesis (inferred); tRNA processing (inferred); ASSOCIATED WITH cardiomyopathy (ortholog); dilated cardiomyopathy (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); tRNA-splicing ligase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bi sphenol A; cadmium dichloride | 9 | 52863565 | 52874234 | Rat | 58 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306941 | C9h2orf69 | similar to human chromosome 2 open reading frame 69 | INVOLVED IN oxidative phosphorylation (ortholog); ASSOCIATED WITH combined oxidative phosphorylation deficiency 53 (ortholog); genetic disease (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 9 | 66444084 | 66452720 | Rat | 39 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305516 | Cables1 | Cdk5 and Abl enzyme substrate 1 | INVOLVED IN nervous system development (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 1-benzylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 18 | 3349681 | 3455956 | Rat | 123 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359269 | Cabp7 | calcium binding protein 7 | ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN gene expression (ortholog); muscle contraction (ortholog); muscle tissue development (ortholog); FOUND IN trans-Golgi network membrane (ortholog); INTERACTS WITH 3,4-methylenedioxymethamphetamin e; 6-propyl-2-thiouracil; bisphenol A | 14 | 83822322 | 83832667 | Rat | 51 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308127 | Cacul1 | CDK2-associated, cullin domain 1 | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN G1/S transition of mitotic cell cycle (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of protein kinase activity (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog) ; INTERACTS WITH acrylamide; bisphenol A; flutamide | 1 | 269652356 | 269712265 | Rat | 52 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305678 | Cadm2 | cell adhesion molecule 2 | INVOLVED IN synaptic membrane adhesion; ASSOCIATED WITH autism spectrum disorder (ortholog); hepatocellular carcinoma (ortholog); malignant astrocytoma (ortholog); FOUND IN axon; GABA-ergic synapse; glutamatergic synapse; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrac hlorodibenzodioxine | 11 | 17994856 | 18971895 | Rat | 91 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306102 | Cage1 | cancer antigen 1 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 17 | 26995671 | 27033740 | Rat | 29 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310950 | Camsap2 | calmodulin regulated spectrin-associated protein family, member 2 | ENCODES a protein that exhibits microtubule minus-end binding (ortholog); INVOLVED IN axon development; regulation of dendrite development; microtubule cytoskeleton organization (ortholog); ASSOCIATED WITH primary ovarian insufficiency (ortholog); FOUND IN centrosome (ortholog); ciliary basal body ( ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 13 | 50274950 | 50354298 | Rat | 124 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304855 | Capn7 | calpain 7 | ENCODES a protein that exhibits endopeptidase activity (ortholog); MIT domain binding (ortholog); INVOLVED IN positive regulation of epithelial cell migration (ortholog); proteolysis (ortholog); self proteolysis (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A | 16 | 6552048 | 6588317 | Rat | 81 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306058 | Card19 | caspase recruitment domain family, member 19 | INVOLVED IN obsolete positive regulation of NF-kappaB transcription factor activity (ortholog); protein catabolic process (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 17 | 15638973 | 15651720 | Rat | 60 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306822 | Carf | calcium responsive transcription factor | ENCODES a protein that exhibits DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to calcium ion; obsolete regulation of DNA-binding transcription fact or activity (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coronary artery disease (ortholog); FOUND IN nucleus; granular component (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 9 | 68996419 | 69046480 | Rat | 79 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308234 | Carns1 | carnosine synthase 1 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); carnosine synthase activity (ortholog); homocarnosine synthase activity (ortholog); INVOLVED IN carnosine biosynthetic process (ortholog); response to peptide (ortholog); PARTICIPATES IN histidine metabolic pathway; histidinemia pat hway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; atrazine | 1 | 210888520 | 210899311 | Rat | 75 | PANTHER | gene, protein-coding, INFERRED [RefSeq] |
| 1307620 | Catsper2 | cation channel, sperm associated 2 | ENCODES a protein that exhibits voltage-gated calcium channel activity (ortholog); INVOLVED IN calcium ion transport (ortholog); fertilization (ortholog); flagellated sperm motility (ortholog); ASSOCIATED WITH Deafness-Infertility Syndrome (ortholog); infertility (ortholog); male infertility (orthol og); FOUND IN CatSper complex (ortholog); sperm flagellum (ortholog); sperm principal piece (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 128822387 | 128842501 | Rat | 96 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305700 | Catsper3 | cation channel, sperm associated 3 | ENCODES a protein that exhibits voltage-gated calcium channel activity (ortholog); INVOLVED IN flagellated sperm motility (ortholog); sodium ion transport (ortholog); sperm capacitation (ortholog); FOUND IN acrosomal vesicle (ortholog); CatSper complex (ortholog); endoplasmic reticulum (ortholog); I NTERACTS WITH arsane; arsenic atom; bisphenol A | 17 | 8820738 | 8846063 | Rat | 48 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310942 | Catsperg | catsper channel auxiliary subunit gamma | FOUND IN sperm principal piece (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 1 | 93616209 | 93646970 | Rat | 62 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307185 | Cbarp | CACN subunit beta associated regulatory protein | ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN negative regulation of voltage-gated calcium channel activity; negative regulation of calcium ion transmembrane transport (ortholog); negative regulation of calcium ion-dependent exocytosis (ortholog); FOUND IN secretory granule; growth cone (ortholog); plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 10217314 | 10225855 | Rat | 91 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310080 | Ccdc116 | coiled-coil domain containing 116 | ASSOCIATED WITH lung cancer (ortholog); FOUND IN centrosome (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; methamphetamine | 11 | 97346927 | 97354827 | Rat | 46 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306081 | Ccdc12 | coiled-coil domain containing 12 | PARTICIPATES IN spliceosome pathway; FOUND IN nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 8 | 119513007 | 119564802 | Rat | 57 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304775 | Ccdc150 | coiled-coil domain containing 150 | INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 9 | 63287962 | 63403644 | Rat | 42 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308523 | Ccdc158 | coiled-coil domain containing 158 | ENCODES a protein that exhibits clathrin binding (ortholog); INVOLVED IN receptor-mediated endocytosis (ortholog); FOUND IN clathrin-coated vesicle (ortholog); early endosome (ortholog); INTERACTS WITH atrazine; bisphenol A; decabromodiphenyl ether | 14 | 15695456 | 15752896 | Rat | 38 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308031 | Ccdc159 | coiled-coil domain containing 159 | INVOLVED IN gene expression (ortholog); regulation of phosphatase activity (ortholog); single fertilization (ortholog); ASSOCIATED WITH male infertility due to acephalic spermatozoa (ortholog); FOUND IN sperm head-tail coupling apparatus (ortholog); INTERACTS WITH (+)-schisandrin B; acrylamide; bisp henol A | 8 | 28733988 | 28742646 | Rat | 48 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305225 | Ccdc174 | coiled-coil domain containing 174 | ASSOCIATED WITH Infantile Hypotonia with Psychomotor Retardation (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 4 | 125949203 | 125976179 | Rat | 55 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308160 | Ccdc178 | coiled-coil domain containing 178 | INVOLVED IN manchette assembly (ortholog); spermatid development (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH bisphenol A; bisphenol AF; indole-3-methanol | 18 | 13349795 | 13747083 | Rat | 28 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1305604 | Ccdc30 | coiled-coil domain containing 30 | INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 5 | 138212067 | 138305465 | Rat | 53 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307516 | Ccdc32 | coiled-coil domain containing 32 | INVOLVED IN cilium organization (ortholog); head development (ortholog); regulation of clathrin-dependent endocytosis (ortholog); ASSOCIATED WITH Cardiofacioneurodevelopmental Syndrome (ortholog); FOUND IN clathrin-coated pit (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyeth anol; bisphenol A | 3 | 126452293 | 126464845 | Rat | 54 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311466 | Ccdc51 | coiled-coil domain containing 51 | ENCODES a protein that exhibits mitochondrial ATP-gated potassium channel activity (ortholog); INVOLVED IN cell volume homeostasis (ortholog); mitochondrial potassium ion transmembrane transport (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH fundus dystrophy (ortholog) ; FOUND IN mitochondrial ATP-gated potassium channel complex (ortholog); mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 8 | 118601002 | 118619943 | Rat | 88 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311912 | Ccdc59 | coiled-coil domain containing 59 | INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; indole-3-methanol | 7 | 43029272 | 43035655 | Rat | 65 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307390 | Ccdc61 | coiled-coil domain containing 61 | ENCODES a protein that exhibits identical protein binding (ortholog); microtubule binding (ortholog); INVOLVED IN centriole assembly (ortholog); mitotic spindle assembly (ortholog); FOUND IN centriolar satellite (ortholog); centriolar subdistal appendage (ortholog); centrosome (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acetamide | 1 | 87665541 | 87685732 | Rat | 72 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310710 | Ccdc77 | coiled-coil domain containing 77 | FOUND IN centrosome (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 155206402 | 155238235 | Rat | 76 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359280 | Ccdc86 | coiled-coil domain containing 86 | INVOLVED IN chromosome segregation (ortholog); mitotic nuclear division (ortholog); ASSOCIATED WITH diffuse large B-cell lymphoma (ortholog); FOUND IN chromosome (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2-nitrofluorene; bisphenol A | 1 | 217015059 | 217021439 | Rat | 119 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305335 | Ccdc89 | coiled-coil domain containing 89 | FOUND IN cytoplasm (inferred); nucleus (inferred); INTERACTS WITH 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil; acrylamide | 1 | 153798786 | 153800048 | Rat | 32 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309393 | Ccdc97 | coiled-coil domain containing 97 | FOUND IN nucleoplasm (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 90347003 | 90354809 | Rat | 39 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302992 | Cchcr1 | coiled-coil alpha-helical rod protein 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN protein export from nucleus (ortholog); ASSOCIATED WITH alopecia areata (ortholog); amphetamine abuse (ortholog); esophagus squamous cell carcinoma (ortholog); FOUND IN centriole (ortholog); cytoplasm (ortholog); cytos ol (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 20 | 3210383 | 3223187 | Rat | 82 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304669 | Ccndbp1 | cyclin D1 binding protein 1 | ASSOCIATED WITH Experimental Liver Neoplasms (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A | 3 | 128416105 | 128427985 | Rat | 60 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310509 | Ccp110 | centriolar coiled-coil protein 110 | ENCODES a protein that exhibits microtubule binding (ortholog); INVOLVED IN centriole replication (ortholog); centrosome duplication (ortholog); ciliary basal body organization (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); microtubule organizing center (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 182475571 | 182504235 | Rat | 95 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311610 | Cd22 | CD22 molecule | ENCODES a protein that exhibits CD4 receptor binding (ortholog); protein phosphatase binding (ortholog); sialic acid binding (ortholog); INVOLVED IN B cell activation (ortholog); negative regulation of B cell receptor signaling pathway (ortholog); negative regulation of calcium-mediated signaling (o rtholog); PARTICIPATES IN B cell receptor signaling pathway; ASSOCIATED WITH diffuse large B-cell lymphoma (ortholog); FOUND IN cell surface (ortholog); early endosome (ortholog); external side of plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 95243785 | 95270430 | Rat | 151 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311513 | Cd226 | CD226 molecule | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); identical protein binding (ortholog); integrin binding (ortholog); INVOLVED IN natural killer cell mediated cytotoxicity (ortholog); positive regulation of Fc receptor mediated stimulatory signaling pathway (ortholog); positi ve regulation of immunoglobulin mediated immune response (ortholog); ASSOCIATED WITH Chronic Hepatitis C (ortholog); Colorectal Neoplasms (ortholog); endometriosis (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 18 | 84723330 | 84819836 | Rat | 97 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306863 | Cd34 | CD34 molecule | ENCODES a protein that exhibits carbohydrate binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); sulfate binding (ortholog); INVOLVED IN glomerular filtration; mesangial cell-matrix adhesion; cell motility (ortholog); ASSOCIATED WITH diabetic retinopat hy; hepatocellular carcinoma (ortholog); Neoplastic Cell Transformation (ortholog); FOUND IN apical plasma membrane; basal plasma membrane; glomerular endothelium fenestra; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 13 | 109008786 | 109029317 | Rat | 210 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309677 | Cd83 | CD83 molecule | INVOLVED IN negative regulation of interleukin-4 production (ortholog); positive regulation of CD4-positive, alpha-beta T cell differentiation (ortholog); positive regulation of interleukin-10 production (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); Experimental Liver Cirrhosis (ortholog ); juvenile rheumatoid arthritis (ortholog); FOUND IN external side of plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 17 | 21093281 | 21113223 | Rat | 211 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306771 | Cdan1 | codanin 1 | INVOLVED IN cell maturation (ortholog); cell morphogenesis (ortholog); chromatin organization (ortholog); ASSOCIATED WITH congenital dyserythropoietic anemia (ortholog); congenital dyserythropoietic anemia type I (ortholog); congenital dyserythropoietic anemia type Ia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endomembrane system (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 3 | 128129664 | 128143520 | Rat | 78 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311342 | Cdc26 | cell division cycle 26 | INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); protein branched polyubiquitination (ortholog); protein K11-linked ubiquitination (ortholog); PARTICIPATES IN cell cycle pathway, mitotic; ubiquitin/proteasome degradation pathway; FOUND IN anaphase-promoting complex (ort holog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 5 | 80861658 | 80875326 | Rat | 89 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307063 | Cdc40 | cell division cycle 40 | INVOLVED IN embryonic brain development (ortholog); mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH pontocerebellar hypoplasia (ortholog); pontocerebellar hypoplasia type 15 (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (o rtholog); nucleoplasm (ortholog); INTERACTS WITH atrazine; bisphenol A; cadmium dichloride | 20 | 45855739 | 45908239 | Rat | 74 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305578 | Cdcp1 | CUB domain containing protein 1 | INVOLVED IN cell population proliferation (ortholog); establishment of protein localization (ortholog); hepatocyte growth factor receptor signaling pathway (ortholog); ASSOCIATED WITH myoepithelioma (ortholog); substance-related disorder (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide | 8 | 131706140 | 131742799 | Rat | 104 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310578 | Cdr2 | cerebellar degeneration-related protein 2 | INVOLVED IN alpha-beta T cell activation involved in immune response (ortholog); cell activation (ortholog); T cell anergy (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 184934128 | 184959036 | Rat | 110 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309211 | Cdt1 | chromatin licensing and DNA replication factor 1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); INVOLVED IN attachment of mitotic spindle microtubules to kinetochore (ortholog); DNA replication checkpoint signaling (ortholog); mitotic DNA replication initiation (ortholog); ASSOCIATED WITH adenine phosphoribos yltransferase deficiency (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN kinetochore (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 19 | 67529249 | 67534195 | Rat | 222 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306754 | Ceacam12 | CEA cell adhesion molecule 12 | INTERACTS WITH bisphenol A | 1 | 87344541 | 87351596 | Rat | 4 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 11382285 | Ceacam15 | CEA cell adhesion molecule 15 | INTERACTS WITH 17beta-estradiol; bisphenol A; amphotericin B (ortholog) | 1 | 86496487 | 86501454 | Rat | 17 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1306386 | Ceacam16 | CEA cell adhesion molecule 16, tectorial membrane component | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN sensory perception of sound (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness 4A (ortholog); autosomal dominant nonsyndromic deafness 4B (ortholog); autosomal recessive nonsyndromic deafness 113 (ort holog); FOUND IN extracellular space (ortholog); stereocilium tip (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 1 | 88642925 | 88652821 | Rat | 43 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309401 | Cend1 | cell cycle exit and neuronal differentiation 1 | INVOLVED IN adult walking behavior (ortholog); cerebellar granular layer maturation (ortholog); cerebellar Purkinje cell differentiation (ortholog); FOUND IN mitochondrion (ortholog); vesicle (ortholog); INTERACTS WITH acrylamide; bisphenol A; thioacetamide | 1 | 205954713 | 205957710 | Rat | 64 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307309 | Cenpm | centromere protein M | ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN chromosome, centromeric region (inferred); cytoplasm (inferred); kinetochore (inferred); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol | 7 | 115628117 | 115639401 | Rat | 131 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310953 | Cenpn | centromere protein N | INVOLVED IN CENP-A containing chromatin assembly (inferred); chromosome segregation (inferred); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil | 19 | 61880101 | 61902850 | Rat | 99 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309383 | Cenpt | centromere protein T | ENCODES a protein that exhibits DNA binding (inferred); protein heterodimerization activity (inferred); INVOLVED IN chromosome organization (ortholog); chromosome segregation (ortholog); kinetochore assembly (ortholog); ASSOCIATED WITH Short Stature and Microcephaly with Genital Anomalies (ortholog) ; FOUND IN chromosome, centromeric region (ortholog); kinetochore (ortholog); nuclear body (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 19 | 50644548 | 50651048 | Rat | 96 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307745 | Cep131 | centrosomal protein 131 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN intraciliary transport (ortholog); intraciliary transport involved in cilium assembly (ortholog); intramanchette transport (ortholog); ASSOCIATED WITH hepatocellul ar carcinoma (ortholog); FOUND IN acrosomal vesicle (ortholog); centriolar satellite (ortholog); centriole (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 4,4'-sulfonyldiphenol | 10 | 105844433 | 105868811 | Rat | 110 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310726 | Cep135 | centrosomal protein 135 | ENCODES a protein that exhibits identical protein binding (ortholog); microtubule binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN centriole replication (ortholog); centriole-centriole cohesion (ortholog); positive regulation of establishment of protein localization (ort holog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness 9 (ortholog); genetic disease (ortholog); primary autosomal recessive microcephaly 8 (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); INTERACTS WITH acrylamide; bisphenol A; glyphosate | 14 | 31884774 | 31950050 | Rat | 86 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307365 | Cep162 | centrosomal protein 162 | INVOLVED IN cilium assembly (ortholog); FOUND IN axonemal microtubule (ortholog); centriole (ortholog); centrosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 8 | 97029677 | 97088243 | Rat | 70 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308517 | Cep44 | centrosomal protein 44 | ENCODES a protein that exhibits microtubule binding (ortholog); INVOLVED IN centriole replication (ortholog); centriole-centriole cohesion (ortholog); centrosome cycle (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorod ibenzofuran; bisphenol A; dibutyl phthalate | 16 | 38722259 | 38741603 | Rat | 78 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305340 | Cep55 | centrosomal protein 55 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cranial skeletal system development (ortholog); establishment of protein localization (ortholog); midbody abscission (ortholog); ASSOCIATED WITH COVID-19 (ortholog); encephalopathy due to defective mitochondrial and pe roxisomal fission 1 (ortholog); genetic disease (ortholog); FOUND IN centrosome (ortholog); cytosol (ortholog); Flemming body (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 1 | 245245272 | 245260835 | Rat | 200 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305183 | Cep76 | centrosomal protein 76 | INVOLVED IN regulation of centriole replication (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); protein-containing complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; aflatoxin B1 | 18 | 63444389 | 63478358 | Rat | 87 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311730 | Cep89 | centrosomal protein 89 | INVOLVED IN cilium assembly (ortholog); mitochondrial respiratory chain complex IV assembly (ortholog); non-motile cilium assembly (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 17beta-estradiol; acrylamide; atrazine | 1 | 97195116 | 97237015 | Rat | 95 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310371 | Cfap161 | cilia and flagella associated protein 161 | INVOLVED IN flagellated sperm motility (ortholog); gene expression (ortholog); motile cilium assembly (ortholog); FOUND IN axonemal A tubule inner sheath (ortholog); axonemal microtubule (ortholog); axoneme (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; fenvalerate | 1 | 147152923 | 147177821 | Rat | 42 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305153 | Cfap184 | cilia and flagella associated protein 184 | FOUND IN cilium (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine | 14 | 78501256 | 78503715 | Rat | 55 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308818 | Cfap210 | cilia and flagella associated protein 210 | INVOLVED IN flagellated sperm motility (ortholog); FOUND IN axonemal B tubule inner sheath (ortholog); axonemal microtubule (ortholog); axoneme (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 74928368 | 74962508 | Rat | 47 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306734 | Cfap53 | cilia and flagella associated protein 53 | ENCODES a protein that exhibits DNA binding (inferred); double-stranded methylated DNA binding (inferred); metal ion binding (inferred); INVOLVED IN cerebrospinal fluid circulation (ortholog); cilium assembly (ortholog); determination of left/right symmetry (ortholog); ASSOCIATED WITH dextrocardia ( ortholog); genetic disease (ortholog); hypoplastic left heart syndrome (ortholog); FOUND IN 9+0 motile cilium (ortholog); 9+2 motile cilium (ortholog); axonemal A tubule inner sheath (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; atrazine | 18 | 70159900 | 70227543 | Rat | 106 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307577 | Cfap70 | cilia and flagella associated protein 70 | INVOLVED IN cell morphogenesis (ortholog); cilium assembly (ortholog); cilium movement (ortholog); ASSOCIATED WITH oligoasthenoteratozoospermia (ortholog); spermatogenic failure 41 (ortholog); FOUND IN axonemal central apparatus (ortholog); axoneme (ortholog); ciliary basal body (ortholog); INTERACT S WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 15 | 3901544 | 3967224 | Rat | 94 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308544 | Cfap90 | cilia and flagella associated protein 90 | INVOLVED IN flagellated sperm motility (ortholog); FOUND IN axonemal B tubule inner sheath (ortholog); axoneme (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 1 | 36654287 | 36678303 | Rat | 14 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307325 | Cfap97 | cilia and flagella associated protein 97 | ASSOCIATED WITH dilated cardiomyopathy (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; all-trans-retinoic acid | 16 | 52818693 | 52867775 | Rat | 46 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308129 | Cggbp1 | CGG triplet repeat binding protein 1 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); double-stranded DNA binding (ortholog); identical protein binding (ortholog); INVOLVED IN epigenetic regulation of gene expression (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FO UND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 11 | 16012251 | 16019388 | Rat | 74 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307652 | Cgm4 | carcinoembryonic antigen gene family 4 | INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 86904526 | 86917487 | Rat | 12 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311283 | Champ1 | chromosome alignment maintaining phosphoprotein 1 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN attachment of mitotic spindle microtubules to kinetochore (ortholog); protein localization to kinetochore (ortholog); protein localization to microtubule (ortholog); ASSOCIATED WITH autosomal domin ant intellectual developmental disorder 40 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); genetic disease (ortholog); FOUND IN condensed chromosome (ortholog); kinetochore (ortholog); nuclear body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 16 | 82436172 | 82447144 | Rat | 75 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307809 | Chchd5 | coiled-coil-helix-coiled-coil-helix domain containing 5 | FOUND IN mitochondrion (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 3 | 136815034 | 136819230 | Rat | 54 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304561 | Chchd6 | coiled-coil-helix-coiled-coil-helix domain containing 6 | INVOLVED IN cristae formation (ortholog); DNA damage response (ortholog); PARTICIPATES IN mitochondrial protein import pathway; FOUND IN MICOS complex (ortholog); mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2, 4,6-trinitrotoluene | 4 | 123360729 | 123581429 | Rat | 122 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310166 | Chct1 | CHD1 helical C-terminal domain containing 1 | FOUND IN nucleus (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; benzo[a]pyrene | 10 | 70537206 | 70548972 | Rat | 20 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311935 | Chd1l | chromodomain helicase DNA binding protein 1-like | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); ATP-dependent chromatin remodeler activity (ortholog); histone reader activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); DNA damage response (ortholog); DNA repair (ortholog); ASSOCIATED WITH CAKUT (ortholog); Dwarfis m (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); site of DNA damage (ortholog); INTERACTS WITH 17beta-estradiol; 2,4,6-trinitrotoluene; 6-propyl-2-thiouracil | 2 | 187819869 | 187906359 | Rat | 126 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310465 | Chd6 | chromodomain helicase DNA binding protein 6 | ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); transcription coregulator binding (ortholog); INVOLVED IN cell redox homeostasis (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 sign aling pathway; ASSOCIATED WITH neuroblastoma (ortholog); Prostatic Neoplasms (ortholog); transitional cell carcinoma (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine | 3 | 170016204 | 170177480 | Rat | 103 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311921 | Chd7 | chromodomain helicase DNA binding protein 7 | ENCODES a protein that exhibits promoter-specific chromatin binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN adult heart development (ortholog); adult walking behavior (ortholog); aorta development (ortholog); PARTICIPATES IN Wnt signa ling, non-canonical pathway; ASSOCIATED WITH 3MC syndrome (ortholog); 46, XY Disorders of Sex Development (ortholog); 46,XY complete gonadal dysgenesis (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 5 | 26609245 | 26792736 | Rat | 271 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306795 | Chd9 | chromodomain helicase DNA binding protein 9 | ENCODES a protein that exhibits ATP binding (inferred); DNA binding (inferred); hydrolase activity (inferred); INVOLVED IN chromatin organization (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorod ibenzofuran | 19 | 32114379 | 32337488 | Rat | 112 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1310473 | Chtf18 | chromosome transmission fidelity factor 18 | ENCODES a protein that exhibits DNA clamp loader activity (ortholog); single-stranded DNA helicase activity (ortholog); INVOLVED IN cell development (ortholog); male meiotic nuclear division (ortholog); negative regulation of chromosome segregation (ortholog); FOUND IN Ctf18 RFC-like complex (orthol og); cytoplasm (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 10 | 15247525 | 15255573 | Rat | 128 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309492 | Cipc | CLOCK-interacting pacemaker | INVOLVED IN negative regulation of circadian rhythm (ortholog); negative regulation of DNA-templated transcription (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; cadmium atom; cadmium dichloride | 6 | 112325980 | 112344692 | Rat | 53 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311989 | Ckap4 | cytoskeleton-associated protein 4 | PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN endoplasmic reticulum (ortholog); lipid droplet (ortholog); rough endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta- estradiol | 7 | 21118527 | 21126624 | Rat | 148 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310274 | Clk4 | CDC-like kinase 4 | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN peptidyl-tyrosine phosphorylation (ortholog); protein autophosphorylation (ortholog); regulation of RNA splicing (ortholog); FOUND IN nucleus (ortholog); INTE RACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 36024364 | 36042366 | Rat | 116 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311930 | Cmah | cytidine monophospho-N-acetylneuraminic acid hydroxylase | ENCODES a protein that exhibits CMP-N-acetylneuraminate monooxygenase activity (ortholog); INVOLVED IN CMP-N-acetylneuraminate metabolic process (ortholog); regulation of Wnt signaling pathway (ortholog); PARTICIPATES IN amino sugar metabolic pathway; nucleotide sugar metabolic pathway; ASSOCIATED W ITH multiple sclerosis (ortholog); FOUND IN cytoplasm (ortholog); cytoskeleton (ortholog); membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; alpha-Zearalanol | 17 | 40985129 | 41070317 | Rat | 103 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306952 | Cmbl | carboxymethylenebutenolidase homolog | ENCODES a protein that exhibits hydrolase activity (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,2',4,4'-Tetrabromodiphenyl ether | 2 | 84280128 | 84301878 | Rat | 184 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308816 | Cnep1r1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1 | ENCODES a protein that exhibits protein phosphatase regulator activity (ortholog); INVOLVED IN positive regulation of triglyceride biosynthetic process (ortholog); protein localization to nucleus (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); Nem1-Spo7 phosphatase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; fipronil | 19 | 35106802 | 35121101 | Rat | 65 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308373 | Cnrip1 | cannabinoid receptor interacting protein 1 | ENCODES a protein that exhibits type 1 cannabinoid receptor binding; INVOLVED IN negative regulation of signaling receptor activity (ortholog); regulation of signaling receptor activity (ortholog); regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission (ortholog) ; FOUND IN cytoplasm (ortholog); GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH all-trans-retinoic acid; bisphenol A; gentamycin | 14 | 95664435 | 95707062 | Rat | 88 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307488 | Cntrob | centrobin, centriole duplication and spindle assembly protein | ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN centriole replication (ortholog); centrosome separation (ortholog); mitotic cytokinetic process (ortholog); ASSOCIATED WITH oligodactyly; ASSOCIATED WITH male infertility due to acephalic spermatozoa; polycystic ovary syndrome (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 54521338 | 54546569 | Rat | 79 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305274 | Coa7 | cytochrome c oxidase assembly factor 7 | ENCODES a protein that exhibits protein-disulfide reductase activity (ortholog); INVOLVED IN mitochondrial respiratory chain complex IV assembly (ortholog); ASSOCIATED WITH autosomal recessive spinocerebellar ataxia with axonal neuropathy 3 (ortholog); basal cell carcinoma (ortholog); genetic diseas e (ortholog); FOUND IN mitochondrial intermembrane space (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 5 | 128298084 | 128308935 | Rat | 83 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1312002 | Cobl | cordon-bleu WH2 repeat protein | ENCODES a protein that exhibits actin monomer binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament network formation (ortholog); actin filament polymerization (ortholog); FOUND IN cell cortex; plasma membrane; actin filament (ortholog); INTERACTS WITH (+)-schisa ndrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 14 | 91041721 | 91274272 | Rat | 186 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308536 | Coch | cochlin | ENCODES a protein that exhibits collagen binding (ortholog); INVOLVED IN regulation of cell shape (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness 9 (ortholog); autosomal recessive nonsyndromic deafness 110 (ortholog); Deafness (ortholog); FOUND IN extracellular matrix (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 6 | 74766485 | 74780504 | Rat | 132 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307149 | Colec10 | collectin subfamily member 10 | ENCODES a protein that exhibits chemoattractant activity (ortholog); D-mannose binding (ortholog); INVOLVED IN complement activation, lectin pathway (ortholog); cranial skeletal system development (ortholog); positive regulation of opsonization (ortholog); ASSOCIATED WITH 3MC syndrome 3 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,4-methylenedioxymethamphetamine | 7 | 87634686 | 87695465 | Rat | 70 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311771 | Commd1 | copper metabolism domain containing 1 | ENCODES a protein that exhibits copper ion binding (ortholog); identical protein binding (ortholog); phosphatidic acid binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); copper ion homeostasis (ortholog); Golgi to plasma membrane transport (ortholog); ASSOCIATED WITH allergic diseas e (ortholog); Chronic Hepatitis (ortholog); Copper-Overload Cirrhosis (ortholog); FOUND IN Cul2-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 6-propyl-2-thiouracil | 14 | 101081667 | 101185738 | Rat | 150 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304773 | Cop1 | COP1, E3 ubiquitin ligase | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of fatty acid biosynthetic process (ortholog); positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein ca tabolic process (ortholog); PARTICIPATES IN p53 signaling pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH abnormal circadian regulation of systemic arterial blood pressure; salt-sensitive hypertension; ASSOCIATED WITH autistic disorder (ortholog); FOUND IN Golgi membrane; Cul4A-RING E3 ubiquitin ligase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 13 | 73954058 | 74095283 | Rat | 71 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310525 | Copa | coat protein complex I subunit alpha | ENCODES a protein that exhibits mRNA binding (ortholog); INVOLVED IN pancreatic juice secretion (ortholog); protein localization to axon (ortholog); protein localization to cell leading edge (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; ASSOCIATED WITH arthritis (ortholog); auto immune disease (ortholog); autoimmune interstitial lung, joint, and kidney disease (ortholog); FOUND IN COPI vesicle coat (ortholog); COPI-coated vesicle (ortholog); cytoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A | 13 | 87078853 | 87119256 | Rat | 125 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303002 | Cops3 | COP9 signalosome subunit 3 | INVOLVED IN in utero embryonic development (ortholog); protein deneddylation (ortholog); regulation of DNA damage response, signal transduction by p53 class mediator (ortholog); ASSOCIATED WITH Hepatomegaly (ortholog); FOUND IN COP9 signalosome (ortholog); cytoplasm (ortholog); cytosol (ortholog); I NTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 10 | 45117664 | 45151868 | Rat | 93 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308245 | Coq8a | coenzyme Q8A | ENCODES a protein that exhibits ADP binding (ortholog); enzyme activator activity (ortholog); kinase activity (ortholog); INVOLVED IN phosphorylation (ortholog); protein phosphorylation (ortholog); ubiquinone biosynthetic process (ortholog); ASSOCIATED WITH autosomal recessive cerebellar ataxia (ort holog); autosomal recessive nonsyndromic deafness 9 (ortholog); cerebellar ataxia (ortholog); FOUND IN extrinsic component of mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 13 | 94436680 | 94465535 | Rat | 194 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309105 | Cox20 | cytochrome c oxidase assembly factor COX20 | INVOLVED IN mitochondrial respiratory chain complex IV assembly (ortholog); ASSOCIATED WITH cytochrome-c oxidase deficiency disease (ortholog); genetic disease (ortholog); mitochondrial complex IV deficiency nuclear type 1 (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion ( ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aconitine; bisphenol A | 13 | 92592260 | 92604129 | Rat | 70 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306568 | Cpped1 | calcineurin-like phosphoesterase domain containing 1 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); protein serine/threonine phosphatase activity (inferred); FOUND IN cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachloro biphenyl | 10 | 4135601 | 4328039 | Rat | 93 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309687 | Cpsf2 | cleavage and polyadenylation specific factor 2 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN mRNA 3'-end processing (ortholog); mRNA 3'-end processing by stem-loop binding and cleavage (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; mRNA decay pathway; FOU ND IN glutamatergic synapse (ortholog); mRNA cleavage and polyadenylation specificity factor complex (ortholog); postsynapse (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 6 | 126885417 | 126917634 | Rat | 114 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310819 | Cracdl | CRACD like | INTERACTS WITH (+)-schisandrin B; 2,2',5,5'-tetrachlorobiphenyl; bisphenol A | 9 | 47323785 | 47446612 | Rat | 48 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311948 | Cramp1 | cramped chromatin regulator 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); FOUND IN histone locus body (ortholog); INTERACTS WITH bisphenol A; paracetamol; thioacetamide | 10 | 14488292 | 14536844 | Rat | 76 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359613 | Creb3l1 | cAMP responsive element binding protein 3-like 1 | ENCODES a protein that exhibits transcription cis-regulatory region binding; cAMP response element binding (ortholog); chromatin binding (ortholog); INVOLVED IN negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; positive regulation of transcription by RNA polymerase II; response to endoplasmic reticulum stress; PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; Huntington's disease pathway; prostate cancer pathway; ASSOCIATED WITH BCARD syndrome (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN chromatin (ortholog); endoplasmic reticulum (ortholog); membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 3 | 98408240 | 98449104 | Rat | 169 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308152 | Creb3l3 | cAMP responsive element binding protein 3-like 3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); response to end oplasmic reticulum stress (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; Huntington's disease pathway; prostate cancer pathway; ASSOCIATED WITH HYPERTRIGLYCERIDEMIA 1 (ortholog); HYPERTRIGLYCERIDEMIA 2 (ortholog); FOUND IN endoplasmic reticulum (ortholog); membrane (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acetamide | 7 | 9273320 | 9281755 | Rat | 161 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308710 | Crim1 | cysteine rich transmembrane BMP regulator 1 | ENCODES a protein that exhibits PDZ domain binding (ortholog); INVOLVED IN negative regulation of BMP signaling pathway (ortholog); negative regulation of osteoblast differentiation (ortholog); FOUND IN extracellular region (inferred); membrane (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 17 beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 22447983 | 22622459 | Rat | 150 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304602 | Crtam | cytotoxic and regulatory T cell molecule | ENCODES a protein that exhibits identical protein binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN activated T cell proliferation (ortholog); cell recognition (ortholog); detection of stimulus (ortholog); FOUND IN immunological synapse (ortholog); plasma membrane (ortholog); IN TERACTS WITH 6-propyl-2-thiouracil; bisphenol A; thioacetamide | 8 | 50237210 | 50274472 | Rat | 116 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311639 | Cryz | crystallin zeta | ENCODES a protein that exhibits mRNA 3'-UTR binding; identical protein binding (ortholog); NADH binding (ortholog); INVOLVED IN mRNA stabilization; protein homotetramerization (ortholog); xenobiotic catabolic process (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN cytosol ( ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 246211707 | 246239472 | Rat | 181 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310219 | Cryzl1 | crystallin zeta like 1 | ENCODES a protein that exhibits identical protein binding (ortholog); FOUND IN early endosome (ortholog); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 4,4'-sulfonyldiphenol; atrazine | 11 | 44419099 | 44464366 | Rat | 68 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309114 | Csf3r | colony stimulating factor 3 receptor | ENCODES a protein that exhibits granulocyte colony-stimulating factor binding (ortholog); INVOLVED IN amelogenesis; neutrophil chemotaxis (ortholog); regulation of myeloid cell differentiation (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WIT H acute myeloid leukemia (ortholog); bacterial pneumonia (ortholog); chronic myelomonocytic leukemia (ortholog); FOUND IN endocytic vesicle membrane (inferred); membrane (inferred); plasma membrane (inferred); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate | 5 | 143583126 | 143604382 | Rat | 136 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309154 | Cst7 | cystatin F | ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (ortholog); peptidase inhibitor activity (ortholog); protease binding (ortholog); INVOLVED IN lysosomal protein catabolic process (ortholog); negative regulation of microglial cell activation (ortholog); positive regulati on of myelination (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 159857221 | 159865987 | Rat | 102 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311032 | Cst9l | cystatin 9-like | ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (inferred); peptidase inhibitor activity (inferred); INVOLVED IN antimicrobial humoral response (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; bisphen ol A | 3 | 156741232 | 156744045 | Rat | 19 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307417 | Cstl1 | cystatin-like 1 | ENCODES a protein that exhibits cysteine-type peptidase activity (ortholog); INVOLVED IN signaling receptor ligand precursor processing (ortholog); INTERACTS WITH bisphenol A; oxybenzone; 4,4'-sulfonyldiphenol (ortholog) | 3 | 156652967 | 156658049 | Rat | 25 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309540 | Cstpp1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN regulation of protein complex stability (ortholog); FOUND IN centriolar satellite (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; acetamide; bisphenol A | 3 | 97704176 | 97872084 | Rat | 53 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311434 | Ctnnal1 | catenin alpha-like 1 | ENCODES a protein that exhibits actin filament binding (inferred); cadherin binding (inferred); INVOLVED IN Rho protein signal transduction (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 5 | 76309546 | 76375869 | Rat | 138 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303306 | Cuta | cutA divalent cation tolerance homolog | ENCODES a protein that exhibits enzyme binding (ortholog); INVOLVED IN intracellular protein localization; FOUND IN membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; aconitine | 20 | 5024816 | 5026446 | Rat | 71 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310958 | Cwh43 | cell wall biogenesis 43 C-terminal homolog | INVOLVED IN brain development (ortholog); cell adhesion (ortholog); cerebrospinal fluid circulation (ortholog); ASSOCIATED WITH Lung Neoplasms (ortholog); normal pressure hydrocephalus (ortholog); FOUND IN extracellular region (inferred); membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; al pha-Zearalanol; bisphenol A | 14 | 35108328 | 35154578 | Rat | 62 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304717 | Cxcl17 | C-X-C motif chemokine ligand 17 | ENCODES a protein that exhibits chemoattractant activity (ortholog); chemokine activity (ortholog); INVOLVED IN cell migration (ortholog); chemokine-mediated signaling pathway (ortholog); leukocyte chemotaxis (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN extracellular space (ortholog); I NTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 1 | 90112561 | 90124648 | Rat | 82 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310755 | Cxxc1 | CXXC finger protein 1 | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding; histone H3K4me3 reader activity (ortholog); unmethylated CpG binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); regulation of DNA-templated transcription (ortholog); PARTI CIPATES IN DNA modification pathway; histone modification pathway; FOUND IN histone methyltransferase complex (ortholog); nuclear matrix (ortholog); nuclear speck (ortholog); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; cadmium dichloride | 18 | 70088407 | 70093786 | Rat | 108 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306605 | Cyp46a1 | cytochrome P450, family 46, subfamily a, polypeptide 1 | ENCODES a protein that exhibits cholesterol 24-hydroxylase activity (ortholog); heme binding (ortholog); steroid hydroxylase activity (ortholog); INVOLVED IN cholesterol catabolic process (ortholog); progesterone metabolic process (ortholog); protein localization to membrane raft (ortholog); PARTICI PATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; ASSOCIATED WITH alcohol use disorder; Alzheimer's disease (ortholog); chronic obstructive pulmonary disease (ortholog); FOUND IN dendrite (ortholog); endoplasmic reticulum membrane (ortholog); postsynapse (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 6 | 133011948 | 133039167 | Rat | 134 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307990 | Cytip | cytohesin 1 interacting protein | INVOLVED IN regulation of cell adhesion (ortholog); FOUND IN cell cortex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil | 3 | 63106895 | 63183769 | Rat | 108 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359578 | Cyyr1 | cysteine and tyrosine rich 1 | FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 11 | 38044003 | 38150391 | Rat | 65 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307976 | D2hgdh | D-2-hydroxyglutarate dehydrogenase | ENCODES a protein that exhibits (R)-2-hydroxyglutarate dehydrogenase activity; zinc ion binding (ortholog); INVOLVED IN lactate metabolic process; malate metabolic process; response to calcium ion; ASSOCIATED WITH 2-hydroxyglutaric aciduria (ortholog); amino acid metabolic disorder (ortholog); D-2-h ydroxyglutaric aciduria (ortholog); FOUND IN mitochondrion; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 9 | 101796287 | 101815727 | Rat | 103 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359206 | Dalrd3 | DALR anticodon binding domain containing 3 | ENCODES a protein that exhibits tRNA binding (ortholog); INVOLVED IN tRNA C3-cytosine methylation (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 86 (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 8 | 118142009 | 118147082 | Rat | 71 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305854 | Dbf4 | DBF4-CDC7 kinase regulatory subunit | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); zinc ion binding (inferred); PARTICIPATES IN cell cycle pathway, mitotic; FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tet rachlorodibenzodioxine; 6-propyl-2-thiouracil | 4 | 26631491 | 26656080 | Rat | 138 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304881 | Dcaf15 | DDB1 and CUL4 associated factor 15 | ENCODES a protein that exhibits small molecule binding (ortholog); INVOLVED IN protein polyubiquitination (ortholog); regulation of natural killer cell activation (ortholog); FOUND IN Cul4-RING E3 ubiquitin ligase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisph enol A | 19 | 40958693 | 40966043 | Rat | 53 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306241 | Dcaf4 | DDB1 and CUL4 associated factor 4 | FOUND IN Cul4-RING E3 ubiquitin ligase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 6 | 108885970 | 108912116 | Rat | 80 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307211 | Dcbld1 | discoidin, CUB and LCCL domain containing 1 | ASSOCIATED WITH intellectual disability (ortholog); melanoma (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 20 | 32161241 | 32254391 | Rat | 71 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309547 | Dctn3 | dynactin subunit 3 | INVOLVED IN cytoskeleton-dependent cytokinesis (ortholog); microtubule-based process (ortholog); PARTICIPATES IN mitochondria transport pathway; FOUND IN dynactin complex; microtubule; centrosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A | 5 | 61676950 | 61684958 | Rat | 69 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305654 | Dctn5 | dynactin subunit 5 | INVOLVED IN aorta development (ortholog); coronary vasculature development (ortholog); microtubule-based process (ortholog); PARTICIPATES IN mitochondria transport pathway; vasopressin signaling pathway via receptor type 2; FOUND IN centrosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodio xine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 186120415 | 186137146 | Rat | 65 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309979 | Ddrgk1 | DDRGK domain containing 1 | ENCODES a protein that exhibits ubiquitin-like protein ligase binding (ortholog); UFM1-modified protein reader activity (ortholog); INVOLVED IN negative regulation of apoptotic process; regulation of insulin secretion involved in cellular response to glucose stimulus; cartilage development (ortholog ); ASSOCIATED WITH Desbuquois dysplasia (ortholog); genetic disease (ortholog); Spondyloepimetaphyseal Dysplasia, Shohat Type (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; leflunomide | 3 | 138315006 | 138336691 | Rat | 128 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303246 | Dek | DEK proto-oncogene | ENCODES a protein that exhibits histone binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase III (ortholog); regulation of double-strand break repair (ortholog); regulation of double-strand break repair via nonhomologous end joining (ortholog); ASSOCIATED WITH Anima l Disease Models (ortholog); Breast Neoplasms (ortholog); Neoplasm Invasiveness (ortholog); FOUND IN contractile muscle fiber (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 17 | 17786989 | 17809096 | Rat | 169 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308326 | Dennd10 | DENN domain containing 10 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN endosome transport via multivesicular body sorting pathway (ortholog); protein transport (ortholog); regulation of early endosome to late endosome transport (ortholog); FOUND IN late endosome (ortholog); INTERACTS WITH bisphenol A; clozapine; flutamide | 1 | 269937023 | 269960506 | Rat | 56 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306064 | Dennd6a | DENN domain containing 6A | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN positive regulation of cell-cell adhesion mediated by cadherin (ortholog); FOUND IN cytoplasm (ortholog); recycling endosome (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; amitrole | 16 | 1843803 | 1892165 | Rat | 63 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311243 | Dhrs7b | dehydrogenase/reductase 7B | ENCODES a protein that exhibits acylglycerone-phosphate reductase (NADP+) activity (ortholog); DNA-binding transcription factor binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN adipose tissue development (ortholog); brown fat cell differentiation (ortholog); ether lipid biosynthetic process (ortholog); FOUND IN membrane (ortholog); nucleus (ortholog); peroxisomal membrane (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil | 10 | 46003845 | 46036498 | Rat | 96 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305820 | Disp3 | dispatched RND transporter family member 3 | INVOLVED IN negative regulation of neuron differentiation (ortholog); positive regulation of lipid metabolic process (ortholog); positive regulation of neural precursor cell proliferation (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; methoxyc hlor | 5 | 163955160 | 164003980 | Rat | 52 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305071 | Dleu7 | deleted in lymphocytic leukemia, 7 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 15 | 40655563 | 40671759 | Rat | 26 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308753 | Dlg5 | discs large MAGUK scaffold protein 5 | ENCODES a protein that exhibits beta-catenin binding (ortholog); cytoskeletal protein binding (ortholog); INVOLVED IN apical protein localization (ortholog); epithelial to mesenchymal transition (ortholog); epithelial tube branching involved in lung morphogenesis (ortholog); ASSOCIATED WITH YUKSEL-V OGEL-BAUER SYNDROME (ortholog); FOUND IN adherens junction (ortholog); cell junction (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aconitine | 15 | 125287 | 237334 | Rat | 141 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311247 | Dlgap5 | DLG associated protein 5 | INVOLVED IN signaling (inferred); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); mitotic spindle (ortholog); nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 23113678 | 23144281 | Rat | 206 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309148 | Dmac1 | distal membrane arm assembly component 1 | INVOLVED IN mitochondrial respiratory chain complex I assembly (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 5 | 94288900 | 94290053 | Rat | 55 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359596 | Dnaaf8 | dynein axonemal assembly factor 8 | ENCODES a protein that exhibits dynein complex binding (ortholog); INVOLVED IN outer dynein arm assembly (ortholog); FOUND IN cytoplasm (ortholog); dynein axonemal particle (ortholog); INTERACTS WITH bisphenol A; paracetamol; butanal (ortholog) | 10 | 11107988 | 11121475 | Rat | 17 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307373 | Dnajb11 | DnaJ heat shock protein family (Hsp40) member B11 | ENCODES a protein that exhibits misfolded protein binding (ortholog); signaling receptor binding (ortholog); unfolded protein binding (ortholog); INVOLVED IN mRNA modification (ortholog); negative regulation of neurogenesis (ortholog); positive regulation of ATP-dependent activity (ortholog); PARTIC IPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; ASSOCIATED WITH autosomal dominant polycystic kidney disease (ortholog); cystic kidney disease (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum chaperone complex; cytoplasm (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 11 | 91656334 | 91672800 | Rat | 208 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307813 | Dnajc10 | DnaJ heat shock protein family (Hsp40) member C10 | ENCODES a protein that exhibits ATPase activator activity (ortholog); ATPase binding (ortholog); disulfide oxidoreductase activity (ortholog); INVOLVED IN ERAD pathway (ortholog); intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (ortholog); protein folding in endopla smic reticulum (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH disease of cellular proliferation (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum chaperone complex (ortholog); endoplasmic reticulum lumen (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A | 3 | 85636890 | 85679620 | Rat | 167 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307731 | Dnajc11 | DnaJ heat shock protein family (Hsp40) member C11 | INVOLVED IN cristae formation (ortholog); FOUND IN MICOS complex (ortholog); mitochondrial outer membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 5 | 167724776 | 167770032 | Rat | 70 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308015 | Dnajc17 | DnaJ heat shock protein family (Hsp40) member C17 | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN cytoplasm; nucleus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 3 | 126616043 | 126649599 | Rat | 61 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311098 | Dnajc22 | DnaJ heat shock protein family (Hsp40) member C22 | FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 7 | 132136516 | 132141802 | Rat | 58 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359589 | Dnajc28 | DnaJ heat shock protein family (Hsp40) member C28 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 11 | 44341528 | 44344348 | Rat | 53 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308693 | Dnajc4 | DnaJ heat shock protein family (Hsp40) member C4 | FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 1 | 213607397 | 213611614 | Rat | 57 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303226 | Dnajc7 | DnaJ heat shock protein family (Hsp40) member C7 | ENCODES a protein that exhibits heat shock protein binding (ortholog); INVOLVED IN protein folding (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); epilepsy (ortholog); human immunodeficiency virus infectious disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 86018977 | 86055419 | Rat | 97 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305009 | Dnajc9 | DnaJ heat shock protein family (Hsp40) member C9 | ENCODES a protein that exhibits heat shock protein binding (ortholog); histone binding (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN nucleosome assembly (ortholog); positive regulation of ATP-dependent activity (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); ex tracellular space (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 15 | 3970843 | 4003009 | Rat | 129 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307447 | Dolpp1 | dolichyldiphosphatase 1 | ENCODES a protein that exhibits dolichyldiphosphatase activity (ortholog); INVOLVED IN protein N-linked glycosylation (ortholog); PARTICIPATES IN N-linked glycan biosynthetic pathway; FOUND IN endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; c admium dichloride | 3 | 34063825 | 34072133 | Rat | 67 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307621 | Dorip1 | dopamine receptor interacting protein 1 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 6 | 88701651 | 88710204 | Rat | 45 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307648 | Dpcd | deleted in primary ciliary dyskinesia | INVOLVED IN determination of left/right symmetry (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); flagellated sperm motility (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); hydrocephalus (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 1 | 254357755 | 254375918 | Rat | 52 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304868 | Dph7 | diphthamide biosynthesis 7 | ENCODES a protein that exhibits diphthine methylesterase activity (inferred); hydrolase activity (inferred); INVOLVED IN protein histidyl modification to diphthamide (ortholog); ASSOCIATED WITH prostate cancer (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; fenvalerate | 3 | 28168466 | 28177173 | Rat | 49 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310120 | Dpm1 | dolichyl-phosphate mannosyltransferase subunit 1, catalytic | ENCODES a protein that exhibits dolichyl-phosphate beta-D-mannosyltransferase activity (ortholog); INVOLVED IN dolichol phosphate mannose biosynthetic process (ortholog); dolichyl monophosphate biosynthetic process (ortholog); GPI anchor biosynthetic process (ortholog); PARTICIPATES IN N-linked glyc an biosynthetic pathway; ASSOCIATED WITH congenital disorder of glycosylation Ie (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN dolichol-phosphate-mannose synthase complex (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; aconitine | 3 | 177338855 | 177358398 | Rat | 116 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305201 | Dr1 | down-regulator of transcription 1 | ENCODES a protein that exhibits RNA polymerase II general transcription initiation factor activity (ortholog); TBP-class protein binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); regulation of cell cycle (ortholog); regulation of cell division (ort holog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; FOUND IN ATAC complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 14 | 1603203 | 1614556 | Rat | 99 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305351 | Drc12 | dynein regulatory complex subunit 12 homolog | ENCODES a protein that exhibits identical protein binding (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 8 | 53468344 | 53481168 | Rat | 47 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308593 | Drc8 | dynein regulatory complex subunit 8 | ENCODES a protein that exhibits calcium ion binding (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN sperm principal piece (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 13 | 92683182 | 92769939 | Rat | 71 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311606 | Drc9 | dynein regulatory complex subunit 9 | ENCODES a protein that exhibits calmodulin binding (ortholog); Hsp70 protein binding (ortholog); INVOLVED IN sperm axoneme assembly (ortholog); spermatid development (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); manchette (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradio l; 2,3,7,8-tetrachlorodibenzodioxine | 11 | 81235204 | 81276249 | Rat | 108 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311143 | Dsg2 | desmoglein 2 | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); INVOLVED IN maternal process involved in female pregnancy; response to progesterone; bundle of His cell-Purkinje myocyte adhesion involved in cell communication (ortholog); PARTICIPATES IN arrhythmogenic right ventricular car diomyopathy pathway; ASSOCIATED WITH Cardiomegaly; dilated cardiomyopathy; arrhythmogenic right ventricular cardiomyopathy (ortholog); FOUND IN apical plasma membrane; intercalated disc; lateral plasma membrane; INTERACTS WITH 17beta-estradiol; bis(2-ethylhexyl) phthalate; bisphenol A | 18 | 12121287 | 12179590 | Rat | 251 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309138 | Dtd2 | D-aminoacyl-tRNA deacylase 2 | ENCODES a protein that exhibits Ala-tRNA(Thr) deacylase activity (ortholog); D-tyrosyl-tRNA(Tyr) deacylase activity (ortholog); INVOLVED IN aminoacyl-tRNA metabolism involved in translational fidelity (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH (+)-schisandrin B; bisphenol A; flutamide | 6 | 75185496 | 75191774 | Rat | 75 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309614 | Dtymk | deoxythymidylate kinase | ENCODES a protein that exhibits ATP binding (ortholog); dTMP kinase activity (ortholog); INVOLVED IN dTDP biosynthetic process; dTTP biosynthetic process; myoblast differentiation; PARTICIPATES IN pyrimidine metabolic pathway; ASSOCIATED WITH Experimental Liver Neoplasms; NEURODEGENERATION, CHILDHOO D-ONSET, WITH PROGRESSIVE MICROCEPHALY (ortholog); FOUND IN mitochondrial matrix; mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 9 | 101762899 | 101771733 | Rat | 163 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305612 | Dus2 | dihydrouridine synthase 2 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); FMN binding (ortholog); NADPH binding (ortholog); INVOLVED IN antiviral innate immune response (ortholog); tRNA dihydrouridine synthesis (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-t etrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 19 | 50816306 | 50864559 | Rat | 80 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307457 | Dusp19 | dual specificity phosphatase 19 | ENCODES a protein that exhibits JUN kinase phosphatase activity (ortholog); MAP-kinase scaffold activity (ortholog); mitogen-activated protein kinase kinase binding (ortholog); INVOLVED IN JNK cascade (ortholog); negative regulation of JNK cascade (ortholog); negative regulation of MAPK cascade (ort holog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; FOUND IN cytoplasm (ortholog); INTERACTS WITH amphetamine; bisphenol A; cobalt dichloride | 3 | 85945289 | 86081289 | Rat | 63 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304571 | Ebpl | EBP like | ENCODES a protein that exhibits cholestenol delta-isomerase activity (inferred); INVOLVED IN sterol metabolic process (inferred); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 39684140 | 39707537 | Rat | 79 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310224 | Eci3 | enoyl-Coenzyme A delta isomerase 3 | ENCODES a protein that exhibits delta(3)-delta(2)-enoyl-CoA isomerase activity (inferred); fatty-acyl-CoA binding (inferred); isomerase activity (inferred); FOUND IN peroxisome (inferred); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 17 | 30127425 | 30149249 | Rat | 33 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306820 | Edrf1 | erythroid differentiation regulatory factor 1 | INVOLVED IN positive regulation of DNA-templated transcription (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; cefaloridine | 1 | 197869873 | 197908693 | Rat | 56 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311056 | Eef1e1 | eukaryotic translation elongation factor 1 epsilon 1 | INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of cell population proliferation (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); progeria (ortholog); stomach cancer (ortholog); FOUND IN aminoac yl-tRNA synthetase multienzyme complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol | 17 | 26354247 | 26364953 | Rat | 121 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302939 | Eef1g | eukaryotic translation elongation factor 1 gamma | ENCODES a protein that exhibits translation elongation factor activity (inferred); INVOLVED IN response to virus (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8- tetrachlorodibenzodioxine | 1 | 215289815 | 215300421 | Rat | 144 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307943 | Efcab10 | EF-hand calcium binding domain 10 | ENCODES a protein that exhibits calcium ion binding (inferred); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; copper atom | 6 | 55731902 | 55738821 | Rat | 33 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305423 | Efcab3 | EF-hand calcium binding domain 3 | ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 10 | 90084495 | 90577145 | Rat | 34 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309650 | Efcab5 | EF-hand calcium binding domain 5 | ENCODES a protein that exhibits calcium ion binding (inferred); INTERACTS WITH 3-chloropropane-1,2-diol; atrazine; bisphenol A | 10 | 62424548 | 62540890 | Rat | 22 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305976 | Efr3a | EFR3 homolog A | INVOLVED IN protein localization to plasma membrane (ortholog); synaptic vesicle priming (ortholog); FOUND IN cytosol (ortholog); glutamatergic synapse (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aconitine | 7 | 99441764 | 99522454 | Rat | 82 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302972 | Ehmt2 | euchromatic histone lysine methyltransferase 2 | ENCODES a protein that exhibits C2H2 zinc finger domain binding (ortholog); H1-4K26 methyltransferase activity (ortholog); histone H3K27 methyltransferase activity (ortholog); INVOLVED IN cellular response to xenobiotic stimulus; long-term memory; regulation of protein modification process; PARTICIP ATES IN histone modification pathway; lysine degradation pathway; ASSOCIATED WITH Binge Drinking; fetal alcohol spectrum disorder; acute lymphoblastic leukemia (ortholog); FOUND IN nucleus; chromatin (ortholog); nuclear speck (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol | 20 | 3924263 | 3941238 | Rat | 230 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306419 | Elp2 | elongator acetyltransferase complex subunit 2 | ENCODES a protein that exhibits protein kinase binding (ortholog); RNA polymerase II complex binding (ortholog); INVOLVED IN regulation of receptor signaling pathway via JAK-STAT (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal recessive intellectual developmental disorder 48 (ortholog); autosomal recessive intellectual developmental disorder 58 (ortholog); FOUND IN cytosol (ortholog); elongator holoenzyme complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol | 18 | 16160686 | 16196307 | Rat | 99 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303303 | Elp5 | elongator acetyltransferase complex subunit 5 | INVOLVED IN positive regulation of cell migration (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); elongator holoenzyme complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 10 | 55191223 | 55202949 | Rat | 86 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311209 | Emilin1 | elastin microfibril interfacer 1 | ENCODES a protein that exhibits extracellular matrix constituent conferring elasticity (ortholog); identical protein binding (ortholog); integrin binding involved in cell-matrix adhesion (ortholog); INVOLVED IN aortic valve morphogenesis (ortholog); cell adhesion mediated by integrin (ortholog); cel l migration (ortholog); ASSOCIATED WITH arterial tortuosity syndrome (ortholog); ARTERIAL TORTUOSITY-BONE FRAGILITY SYNDROME (ortholog); autosomal dominant distal hereditary motor neuronopathy 10 (ortholog); FOUND IN EMILIN complex (ortholog); extracellular matrix (ortholog); extracellular space (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 6 | 31175919 | 31183657 | Rat | 173 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307666 | Enah | ENAH, actin regulator | ENCODES a protein that exhibits profilin binding (ortholog); SH3 domain binding (ortholog); WW domain binding (ortholog); INVOLVED IN postsynaptic cytoskeleton organization; actin cytoskeleton organization (ortholog); actin filament organization (ortholog); PARTICIPATES IN E-cadherin signaling pathw ay; ASSOCIATED WITH acute myeloid leukemia (ortholog); hepatocellular carcinoma (ortholog); stomach cancer (ortholog); FOUND IN GABA-ergic synapse; postsynapse; cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 3,3',4,4',5-pentachlorobiphenyl; cadmium dichloride | 13 | 96149437 | 96269841 | Rat | 152 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310868 | Engase | endo-beta-N-acetylglucosaminidase | ENCODES a protein that exhibits mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity (ortholog); INVOLVED IN protein deglycosylation (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol | 10 | 104205753 | 104218416 | Rat | 69 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309016 | Enoph1 | enolase-phosphatase 1 | ENCODES a protein that exhibits acireductone synthase activity (ortholog); INVOLVED IN L-methionine salvage from methylthioadenosine (ortholog); PARTICIPATES IN cysteine and methionine metabolic pathway; ASSOCIATED WITH pneumoconiosis (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred); IN TERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate; bisphenol A | 14 | 9835626 | 9862051 | Rat | 88 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 150342294 | ENSRNOG00000063631 | | ENCODES an protein_coding that exhibits histone H3K9 methyltransferase activity (inferred); histone H3K9 trimethyltransferase activity (inferred); histone H3K9me2 methyltransferase activity (inferred); INVOLVED IN cell differentiation (inferred); chromatin organization (inferred); DNA-templated tran scription (inferred); FOUND IN chromatin silencing complex (inferred); chromosome, centromeric region (inferred); heterochromatin (inferred) | | | | Rat | 26 | PANTHER | gene, protein_coding |
| 150344099 | ENSRNOG00000066183 | | INVOLVED IN regulation of transcription by RNA polymerase II (inferred) | | | | Rat | 1 | PANTHER | gene, protein_coding |
| 150341139 | ENSRNOG00000067513 | | ENCODES an protein_coding that exhibits metal ion binding (inferred); zinc ion binding (inferred); FOUND IN cytoplasm (inferred) | | | | Rat | 3 | PANTHER | gene, protein_coding |
| 150345862 | ENSRNOG00000068353 | | ENCODES an protein_coding that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription, elongation (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (in ferred) | | | | Rat | 13 | PANTHER | gene, protein_coding |
| 150344096 | ENSRNOG00000068816 | | FOUND IN mitochondrial large ribosomal subunit (inferred); mitochondrion (inferred); ribonucleoprotein complex (inferred) | | | | Rat | 7 | PANTHER | gene, protein_coding |
| 150343280 | ENSRNOG00000069569 | | ENCODES an protein_coding that exhibits nucleic acid binding (inferred); FOUND IN cytoplasm (inferred); nucleus (inferred) | | | | Rat | 5 | PANTHER | gene, protein_coding |
| 1304733 | Ep400 | E1A binding protein p400 | ENCODES a protein that exhibits chromatin binding; protein antigen binding; INVOLVED IN gene expression (ortholog); nervous system development (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 family mediated chromatin remode ling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 12 | 51551665 | 51658635 | Rat | 136 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359161 | Epdr1 | ependymin related 1 | ENCODES a protein that exhibits ganglioside GM1 binding (ortholog); identical protein binding (ortholog); phospholipid binding (ortholog); INVOLVED IN myofibroblast contraction (ortholog); ASSOCIATED WITH angle-closure glaucoma (ortholog); FOUND IN extracellular region (ortholog); lysosome (ortholog ); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 17 | 50029591 | 50054254 | Rat | 114 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304714 | Eral1 | Era-like 12S mitochondrial rRNA chaperone 1 | ENCODES a protein that exhibits ribosomal small subunit binding (ortholog); RNA folding chaperone (ortholog); rRNA binding (ortholog); INVOLVED IN mitochondrial small ribosomal subunit assembly (ortholog); ribosomal small subunit assembly (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Hearing Loss (ortholog); Perrault syndrome (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 10 | 63459774 | 63466829 | Rat | 89 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309109 | Ercc2 | ERCC excision repair 2, TFIIH core complex helicase subunit | ENCODES a protein that exhibits 5'-3' DNA helicase activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN embryonic organ development; response to hypoxia; apoptotic process (ortholog); PARTICIPATES IN altered nucleotide excision repair pathway; nucleotide excision repai r pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH asphyxia neonatorum; acoustic neuroma (ortholog); acquired immunodeficiency syndrome (ortholog); FOUND IN transcription factor TFIIH core complex; CAK-ERCC2 complex (ortholog); cytoplasm (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; aflatoxin B1; bisphenol A | 1 | 88161342 | 88175102 | Rat | 318 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311570 | Ercc8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN response to auditory stimulus; DNA damage response (ortholog); double-strand break repair via classical nonhomologous end joining (ortholog); PARTICIPATES IN altered nucleotide excision repair pa thway; nucleotide excision repair pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 1A (ortholog); Cockayne syndrome (ortholog); Cockayne syndrome A (ortholog); FOUND IN perikaryon; Cul4-RING E3 ubiquitin ligase complex (ortholog); Cul4A-RING E3 ubiquitin ligase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4,4'-diaminodiphenylmethane | 2 | 41380901 | 41418294 | Rat | 135 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308367 | Ermn | ermin | ENCODES a protein that exhibits actin filament binding (ortholog); INVOLVED IN actin filament organization (ortholog); morphogenesis of a branching structure (ortholog); regulation of cell projection organization (ortholog); FOUND IN cell cortex (ortholog); cytoplasm (ortholog); filopodium (ortholog ); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 3 | 63037001 | 63042657 | Rat | 88 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309176 | Erp44 | endoplasmic reticulum protein 44 | ENCODES a protein that exhibits protein disulfide isomerase activity (ortholog); INVOLVED IN glycoprotein metabolic process (ortholog); protein folding (ortholog); response to endoplasmic reticulum stress (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cell surface (ortholog); e ndoplasmic reticulum lumen (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 5 | 67313245 | 67406207 | Rat | 126 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303286 | Esam | endothelial cell adhesion molecule | ENCODES a protein that exhibits cell-cell adhesion mediator activity (ortholog); identical protein binding (ortholog); INVOLVED IN bicellular tight junction assembly (ortholog); cell-cell adhesion (ortholog); homophilic cell-cell adhesion (ortholog); ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH INTRACRANIAL HEMORRHAGE, SEIZURES, AND SPASTICITY (ortholog); schizophrenia (ortholog); FOUND IN adherens junction (ortholog); bicellular tight junction (ortholog); cell-cell junction (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 8 | 45426985 | 45437976 | Rat | 119 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311034 | Ethe1 | ETHE1, persulfide dioxygenase | ENCODES a protein that exhibits identical protein binding (ortholog); iron ion binding (ortholog); sulfur dioxygenase activity (ortholog); INVOLVED IN glutathione metabolic process (ortholog); hydrogen sulfide metabolic process (ortholog); ASSOCIATED WITH ethylmalonic encephalopathy (ortholog); gene tic disease (ortholog); Nervous System Malformations (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 89311948 | 89327000 | Rat | 153 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305594 | Evx2 | even-skipped homeobox 2 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN limb morphogenesis (ortholog); ASSOCIATED WITH Synpolydactyly 1 (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH bisphenol A; trichloroethene; 1,2-dimethylhydrazine (ortholog) | 3 | 79965630 | 79969700 | Rat | 35 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1304739 | Exosc3 | exosome component 3 | ENCODES a protein that exhibits RNA exonuclease activity (ortholog); INVOLVED IN CUT catabolic process (ortholog); DNA deamination (ortholog); isotype switching (ortholog); PARTICIPATES IN RNA degradation pathway; ASSOCIATED WITH congenital myopathy (ortholog); fetal akinesia deformation sequence sy ndrome 1 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic exosome (RNase complex) (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 5 | 64369495 | 64374711 | Rat | 114 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307861 | Exosc5 | exosome component 5 | ENCODES a protein that exhibits RNA exonuclease activity (ortholog); INVOLVED IN defense response to virus (ortholog); DNA deamination (ortholog); mRNA catabolic process (ortholog); PARTICIPATES IN ribosome biogenesis pathway; RNA degradation pathway; ASSOCIATED WITH CEREBELLAR ATAXIA, BRAIN ABNORMA LITIES, AND CARDIAC CONDUCTION DEFECTS (ortholog); Desbuquois dysplasia (ortholog); Disease Progression (ortholog); FOUND IN cytosol (ortholog); euchromatin (ortholog); exosome (RNase complex) (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol | 1 | 90295495 | 90305047 | Rat | 124 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307684 | Extl2 | exostosin-like glycosyltransferase 2 | ENCODES a protein that exhibits alpha-1,4-N-acetylgalactosaminyltransferase activity (ortholog); glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity (ortholog); glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity (ortholog); INVOLVED IN N-acetylglucosamine metabolic process (ortholog); UDP-N-acetylgalactosamine metabolic process (ortholog); PARTICIPATES IN heparan sulfate biosynthetic pathway; FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 2 | 206607106 | 206631861 | Rat | 91 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305028 | Ezh1 | enhancer of zeste 1 polycomb repressive complex 2 subunit | ENCODES a protein that exhibits chromatin binding; DNA binding (ortholog); histone binding (ortholog); INVOLVED IN hippocampus development; positive regulation of transcription by RNA polymerase II; chromatin remodeling (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH Neurod evelopmental Disorders (ortholog); FOUND IN chromosome, telomeric region (ortholog); ESC/E(Z) complex (ortholog); heterochromatin (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 86626307 | 86662257 | Rat | 147 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310347 | Fa2h | fatty acid 2-hydroxylase | ENCODES a protein that exhibits fatty acid 2-hydroxylase activity; 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity (ortholog); free fatty acid 2-hydroxylase activity (ortholog); INVOLVED IN galactosylceramide biosynthetic process; central nervous system myelin maintenance (ortholog); ceramide biosynthetic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); hereditary spastic paraplegia (ortholog); hereditary spastic paraplegia 35 (ortholog); FOUND IN endoplasmic reticulum (ortholog); membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol | 19 | 56222240 | 56273480 | Rat | 163 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306926 | Faap100 | FA core complex associated protein 100 | INVOLVED IN interstrand cross-link repair (inferred); FOUND IN chromatin (ortholog); Fanconi anaemia nuclear complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 10 | 106140820 | 106152500 | Rat | 51 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1308923 | Faap20 | FA core complex associated protein 20 | ENCODES a protein that exhibits K63-linked polyubiquitin modification-dependent protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); ubiquitin-modified protein reader activity (ortholog); INVOLVED IN DNA damage response (ortholog); interstrand cross-link repai r (ortholog); translesion synthesis (ortholog); FOUND IN chromatin (ortholog); chromosome (ortholog); Fanconi anaemia nuclear complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 5 | 171083328 | 171097599 | Rat | 77 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306577 | Faf2 | Fas associated factor family member 2 | ENCODES a protein that exhibits lipase binding (ortholog); lipase inhibitor activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN ERAD pathway (ortholog); lipid droplet organization (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog) ; ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (ortholog); lipid droplet (ortholog); VCP-NPL4-UFD1 AAA ATPase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 3-chloropropane-1,2-diol | 17 | 9952329 | 9994596 | Rat | 97 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307173 | Fam118b | family with sequence similarity 118, member B | ENCODES a protein that exhibits identical protein binding (ortholog); FOUND IN Cajal body (inferred); INTERACTS WITH 17beta-estradiol; alpha-Zearalanol; bisphenol A | 8 | 41824522 | 41875190 | Rat | 54 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309973 | Fam174a | family with sequence similarity 174, member A | ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F | 9 | 103190144 | 103208419 | Rat | 59 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307805 | Fam209 | family with sequence similarity 209 | INVOLVED IN acrosome assembly (ortholog); spermatid development (ortholog); FOUND IN acrosomal vesicle (ortholog); nuclear inner membrane (ortholog); INTERACTS WITH bisphenol A; cadmium dichloride; decabromodiphenyl ether | 3 | 181658479 | 181660164 | Rat | 37 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359600 | Fam210a | family with sequence similarity 210, member A | ASSOCIATED WITH Bone Fractures (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; aflatoxin B1 | 18 | 64116274 | 64155971 | Rat | 93 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310861 | Fam216a | family with sequence similarity 216, member A | INTERACTS WITH amphetamine; bisphenol A; cadmium atom | 12 | 39859307 | 39868450 | Rat | 57 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305939 | Fam227a | family with sequence similarity 227, member A | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol | 7 | 113054751 | 113096898 | Rat | 37 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310799 | Fam53b | family with sequence similarity 53, member B | INVOLVED IN positive regulation of canonical Wnt signaling pathway (ortholog); regulation of canonical Wnt signaling pathway (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; acrylamide | 1 | 196930170 | 197021290 | Rat | 83 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304756 | Fank1 | fibronectin type III and ankyrin repeat domains 1 | INVOLVED IN negative regulation of apoptotic process (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of DNA-templated transcription (ortholog); FOUND IN chromatin (ortholog); ciliary basal body (ortholog); ciliary base (ortholog); INTERACTS WITH 2,3,7,8-tetrachlo rodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 1 | 198007496 | 198114790 | Rat | 84 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307883 | Fastkd2 | FAST kinase domains 2 | ENCODES a protein that exhibits rRNA binding (ortholog); INVOLVED IN apoptotic process (ortholog); mitochondrial large ribosomal subunit assembly (ortholog); mitochondrial RNA modification (ortholog); ASSOCIATED WITH combined oxidative phosphorylation deficiency 44 (ortholog); cytochrome-c oxidase d eficiency disease (ortholog); genetic disease (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrial nucleoid (ortholog); mitochondrion (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil; alpha-Zearalanol | 9 | 72659961 | 72681986 | Rat | 116 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310662 | Fbf1 | Fas binding factor 1 | INVOLVED IN apical junction assembly (ortholog); cilium assembly (ortholog); establishment of epithelial cell polarity (ortholog); FOUND IN apical junction complex (ortholog); centriole (ortholog); centrosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetami ne | 10 | 101874661 | 101900497 | Rat | 81 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310628 | Fbxo15 | F-box protein 15 | ENCODES a protein that exhibits nucleotide binding (inferred); INVOLVED IN retrotransposition (inferred); FOUND IN SCF ubiquitin ligase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium atom | 18 | 80594444 | 80909549 | Rat | 63 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305095 | Fbxo24 | F-box protein 24 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN axoneme assembly (ortholog); chromatin organization (ortholog); cilium organization (ortholog); FOUND IN nucleus (ortholog); SCF ubiquitin ligase complex (ortholog); INTERACTS WITH bisphenol A; c admium dichloride; endosulfan | 12 | 24709449 | 24719851 | Rat | 56 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307870 | Fbxo36 | F-box protein 36 | INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acetamide | 9 | 93490618 | 93555298 | Rat | 59 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309781 | Fbxo40 | F-box protein 40 | ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN muscle cell differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH alpha-Zearalanol; b isphenol A; cyclophosphamide | 11 | 77299826 | 77318086 | Rat | 32 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304787 | Fbxo42 | F-box protein 42 | INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 5 | 158734165 | 158792560 | Rat | 65 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310225 | Fbxo43 | F-box protein 43 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cellular response to nerve growth factor stimulus; negative regulation of cell cycle process (ortholog); negative regulation of meiotic nuclear division (ortholog); ASSOCIATED WITH Oocyte/Zygote/Em bryo Maturation Arrest 12 (ortholog); spermatogenic failure 64 (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH acrylamide; bisphenol A; gentamycin | 7 | 69218298 | 69231873 | Rat | 68 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310460 | Fbxw2 | F-box and WD repeat domain containing 2 | FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; aflatoxin B1 | 3 | 38486358 | 38511683 | Rat | 46 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306518 | Fbxw4 | F-box and WD repeat domain containing 4 | INVOLVED IN cartilage development (ortholog); embryonic digit morphogenesis (ortholog); limb development (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); split hand-foot malformation (ortholog); split hand-foot malformation 3 (ortholog); INTERACTS WITH bisphenol A; flutamide; T-2 toxin | 1 | 254375921 | 254465173 | Rat | 56 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307556 | Fech | ferrochelatase | ENCODES a protein that exhibits ferrochelatase activity; heme binding (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to dexamethasone stimulus; heme biosynthetic process; response to arsenic-containing substance; PARTICIPATES IN acute intermittent porphyria pathway; erythropoietic porphyria pathway; heme biosynthetic pathway; ASSOCIATED WITH Hepatic Porphyrias; bile duct disease (ortholog); colon adenocarcinoma (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial matrix (ortholog); mitochondrial membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 18 | 60215325 | 60248525 | Rat | 269 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310168 | Fermt3 | FERM domain containing kindlin 3 | ENCODES a protein that exhibits integrin binding (ortholog); lipid binding (ortholog); INVOLVED IN integrin activation (ortholog); integrin-mediated signaling pathway (ortholog); leukocyte cell-cell adhesion (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH ovarian can cer; acute myeloid leukemia (ortholog); blood platelet disease (ortholog); FOUND IN podosome (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 213618691 | 213636889 | Rat | 133 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308978 | Fhl4 | four and a half LIM domains 4 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cell differentiation (inferred); muscle organ development (inferred); FOUND IN cytoplasm (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Butylbenzyl phthalate | 7 | 20516308 | 20521111 | Rat | 12 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307696 | Fitm2 | fat storage-inducing transmembrane protein 2 | ENCODES a protein that exhibits coenzyme A diphosphatase activity (ortholog); diacylglycerol binding (ortholog); triglyceride binding (ortholog); INVOLVED IN fat cell differentiation (ortholog); fatty-acyl-CoA catabolic process (ortholog); intracellular triglyceride homeostasis (ortholog); ASSOCIATE D WITH Siddiqi syndrome (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 172560781 | 172567291 | Rat | 119 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311705 | Fkbp14 | FKBP prolyl isomerase 14 | ENCODES a protein that exhibits calcium ion binding (inferred); isomerase activity (inferred); metal ion binding (inferred); ASSOCIATED WITH congenital contractural arachnodactyly (ortholog); congenital muscular dystrophy (ortholog); Desbuquois dysplasia (ortholog); FOUND IN endoplasmic reticulum (i nferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 4 | 85035840 | 85051917 | Rat | 108 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304816 | Fkbp15 | FKBP prolyl isomerase family member 15 | ENCODES a protein that exhibits actin binding (inferred); isomerase activity (inferred); peptidyl-prolyl cis-trans isomerase activity (inferred); INVOLVED IN endocytosis (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); genetic disease (ortholog); substance-related disorder (ortholog); FOUND IN actin cytoskeleton (ortholog); axon (ortholog); endosome (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 5 | 80766356 | 80830622 | Rat | 82 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304992 | Fkbp3 | FKBP prolyl isomerase 3 | ENCODES a protein that exhibits isomerase activity (inferred); peptidyl-prolyl cis-trans isomerase activity (inferred); FOUND IN cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 6 | 88850137 | 88862542 | Rat | 99 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308926 | Fkbp6 | FKBP prolyl isomerase family member 6 | ENCODES a protein that exhibits Hsp90 protein binding (ortholog); identical protein binding (ortholog); peptidyl-prolyl cis-trans isomerase activity (ortholog); INVOLVED IN spermatogenesis; meiotic cell cycle (ortholog); piRNA processing (ortholog); ASSOCIATED WITH male infertility; genetic disease (ortholog); spermatogenic failure 77 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); fibrillar center (ortholog); INTERACTS WITH bisphenol A; 17alpha-ethynylestradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog) | 12 | 26947443 | 27026913 | Rat | 83 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309238 | Fnbp4 | formin binding protein 4 | FOUND IN nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 97188852 | 97218916 | Rat | 104 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309189 | Fndc7 | fibronectin type III domain containing 7 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A | 2 | 199189029 | 199226425 | Rat | 30 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310708 | Fndc8 | fibronectin type III domain containing 8 | ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); INTERACTS WITH bisphenol A; C60 fullerene; furan | 10 | 68323500 | 68331638 | Rat | 20 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311275 | Foxh1 | forkhead box H1 | ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); co-SMAD binding (ortholog); DNA binding (ortholog); INVOLVED IN hepatocyte differentiation; anterior/posterior pattern specification (ortholog); aorta morphogenesis (ortholog); PARTICIPATES IN transforming growth factor-be ta Smad dependent signaling pathway; ASSOCIATED WITH agnathia-otocephaly complex (ortholog); Conotruncal Cardiac Defects (ortholog); genetic disease (ortholog); FOUND IN activin responsive factor complex (ortholog); chromatin (ortholog); nucleus (ortholog); INTERACTS WITH bis(2-ethylhexyl) phthalate; bisphenol A; cadmium dichloride | 7 | 110268608 | 110272105 | Rat | 148 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309739 | Foxr1 | forkhead box R1 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN brain development (ortholog); positive regulation of transcription by RNA polymerase I I (ortholog); regulation of transcription by RNA polymerase II (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog) | 8 | 53657388 | 53669424 | Rat | 36 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306516 | Fras1 | Fraser extracellular matrix complex subunit 1 | ENCODES a protein that exhibits metal ion binding (inferred); INVOLVED IN embryonic limb morphogenesis (ortholog); metanephros morphogenesis (ortholog); morphogenesis of an epithelium (ortholog); ASSOCIATED WITH Axenfeld-Rieger syndrome (ortholog); CAKUT (ortholog); clubfoot (ortholog); FOUND IN bas ement membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 14 | 13095370 | 13506895 | Rat | 151 | PANTHER | gene, protein-coding, INFERRED [RefSeq] |
| 1309978 | Frrs1l | ferric-chelate reductase 1-like | ENCODES a protein that exhibits dynein intermediate chain binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN regulation of postsynaptic membrane neurotransmitter receptor levels; regulation of AMPA glutamate receptor clustering (ortholog); regulation of glutamate receptor signaling pathway (ortholog); ASSOCIATED WITH choreatic disease (ortholog); developmental and epileptic encephalopathy 37 (ortholog); epilepsy (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); postsynapse (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 5 | 76451101 | 76485319 | Rat | 62 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303047 | Fscn3 | fascin actin-bundling protein 3 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN actin filament organization (inferred); spermatid development (inferred); ASSOCIATED WITH hypospadias (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; acrylamide | 4 | 58008124 | 58017674 | Rat | 57 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310608 | Fuz | fuzzy planar cell polarity protein | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); aorta development (ortholog); cardiac septum development (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); Desbuquois dysplasia (ortholog); neural tube defect (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol | 1 | 104515782 | 104524591 | Rat | 120 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309326 | Fv1 | Friend virus susceptibility 1 | INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; amitrole | 1 | 103867358 | 103873336 | Rat | 48 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308713 | Fzr1 | fizzy and cell division cycle 20 related 1 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); lens fiber cell differentiation (ortholog); mitotic G2 DNA damage checkpoint signaling (ortholog); PARTICIPATES IN cell cycle pa thway, mitotic; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 109 (ortholog); Developmental Disabilities (ortholog); FOUND IN nuclear membrane (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 8982765 | 8994689 | Rat | 119 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309249 | Gadd45gip1 | GADD45G interacting protein 1 | ENCODES a protein that exhibits structural constituent of ribosome (ortholog); INVOLVED IN mitochondrial translation (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog); FOUND IN mitochondrial large ribosomal subunit ( ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol | 19 | 40225503 | 40228052 | Rat | 70 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306483 | Galt | galactose-1-phosphate uridylyltransferase | ENCODES a protein that exhibits UDP-glucose:hexose-1-phosphate uridylyltransferase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN liver development; galactose metabolic process (ortholog); glycolytic process from galactose (ortholog); PARTICIPATES IN galactokinase deficiency pathway; galactose metabolic pathway; galactosemia pathway; ASSOCIATED WITH classic galactosemia (ortholog); galactosemia (ortholog); genetic disease (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 5 | 61722871 | 61726128 | Rat | 125 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308717 | Gart | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | ENCODES a protein that exhibits phosphoribosylamine-glycine ligase activity; phosphoribosylformylglycinamidine cyclo-ligase activity; phosphoribosylglycinamide formyltransferase activity; INVOLVED IN brainstem development; cerebellum development; cerebral cortex development; PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Animal Disease Models (ortholog); Down syndrome (ortholog); esophageal atresia/tracheoesophageal fistula (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 11 | 44351841 | 44377086 | Rat | 228 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308829 | Gcdh | glutaryl-CoA dehydrogenase | ENCODES a protein that exhibits fatty-acyl-CoA binding; flavin adenine dinucleotide binding; glutaryl-CoA dehydrogenase activity; INVOLVED IN acyl-CoA metabolic process; fatty acid oxidation; fatty-acyl-CoA biosynthetic process; PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; carnitine p almitoyltransferase I deficiency pathway; ethylmalonic encephalopathy pathway; ASSOCIATED WITH congenital dyserythropoietic anemia type IVa (ortholog); genetic disease (ortholog); glutaric acidemia I (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 40168038 | 40174536 | Rat | 161 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311813 | Gdpd1 | glycerophosphodiester phosphodiesterase domain containing 1 | ENCODES a protein that exhibits phosphatidylcholine lysophospholipase A1 activity (ortholog); phosphoric diester hydrolase activity (ortholog); INVOLVED IN N-acylethanolamine metabolic process (ortholog); phospholipid metabolic process (ortholog); ASSOCIATED WITH retinitis pigmentosa 1 (ortholog); F OUND IN endoplasmic reticulum (ortholog); membrane (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2,4,6-trinitrotoluene; 3-chloropropane-1,2-diol; acetamide | 10 | 72318716 | 72381143 | Rat | 127 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309854 | Gfm2 | GTP dependent ribosome recycling factor mitochondrial 2 | ENCODES a protein that exhibits GTPase activity (ortholog); translation elongation factor activity (ortholog); INVOLVED IN mitochondrial translation (ortholog); mitochondrial translational elongation (ortholog); ribosome disassembly (ortholog); ASSOCIATED WITH combined oxidative phosphorylation defi ciency 1 (ortholog); combined oxidative phosphorylation deficiency 39 (ortholog); genetic disease (ortholog); FOUND IN mitochondrial matrix (inferred); mitochondrion (inferred); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 2 | 30184063 | 30222811 | Rat | 90 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307028 | Gfus | GDP-L-fucose synthase | ENCODES a protein that exhibits GDP-L-fucose synthase activity (ortholog); GDP-mannose 3,5-epimerase activity (ortholog); identical protein binding (ortholog); INVOLVED IN 'de novo' GDP-L-fucose biosynthetic process (ortholog); GDP-mannose metabolic process (ortholog); positive regulation of endothe lial cell migration (ortholog); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 7 | 109492808 | 109497719 | Rat | 112 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306765 | Ggn | gametogenetin | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN double-strand break repair (ortholog); embryo implantation (ortholog); gamete generation (ortholog); ASSOCIATED WITH spermatogenic failure 69 (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 93598076 | 93601598 | Rat | 48 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303335 | Ggt6 | gamma-glutamyl transferase 6 | ENCODES a protein that exhibits acyltransferase activity (inferred); glutathione hydrolase activity (inferred); hydrolase activity (inferred); INVOLVED IN glutathione biosynthetic process (inferred); glutathione metabolic process (inferred); PARTICIPATES IN glutathione metabolic pathway; glutathione synthase deficiency pathway; glutathionuria disease pathway; FOUND IN membrane (inferred); INTERACTS WITH alpha-Zearalanol; bisphenol A; ochratoxin A | 10 | 57550447 | 57553461 | Rat | 75 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309759 | Ginm1 | glycosylated integral membrane protein 1 | INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil; amitrole | 1 | 4066766 | 4082640 | Rat | 39 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308660 | Gldc | glycine decarboxylase | ENCODES a protein that exhibits enzyme binding; glycine binding; glycine dehydrogenase (decarboxylating) activity; INVOLVED IN glycine decarboxylation via glycine cleavage system; protein-containing complex assembly; cellular response to leukemia inhibitory factor (ortholog); PARTICIPATES IN dihydro pyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; folate cycle metabolic pathway; ASSOCIATED WITH COVID-19 (ortholog); Developmental Disabilities (ortholog); generalized epilepsy (ortholog); FOUND IN glycine cleavage complex; mitochondrion (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 3-chloropropane-1,2-diol | 1 | 237296753 | 237375620 | Rat | 198 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303130 | Glmp | glycosylated lysosomal membrane protein | INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); protein localization to lysosome (ortholog); protein stabilization (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cytosol (ortholog); lysosome (ortholog); membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrab romodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 2 | 176092098 | 176095688 | Rat | 88 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307010 | Glod4 | glyoxalase domain containing 4 | FOUND IN mitochondrion (inferred); INTERACTS WITH (R,R,R)-alpha-tocopherol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 10 | 61575770 | 61594111 | Rat | 72 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307950 | Glrx2 | glutaredoxin 2 | ENCODES a protein that exhibits protein-disulfide reductase activity (ortholog); INVOLVED IN cellular response to superoxide; FOUND IN dendrite; mitochondrial matrix; neuronal cell body; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol | 13 | 58032199 | 58055061 | Rat | 112 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 11474029 | Glrxl1 | glutaredoxin like 1 | | 15 | 20235912 | 20240560 | Rat | 1 | PANTHER | gene, ncrna, MODEL [RefSeq] |
| 1311008 | Gmds | GDP-mannose 4, 6-dehydratase | ENCODES a protein that exhibits GDP-mannose 4,6-dehydratase activity (ortholog); identical protein binding (ortholog); NADP+ binding (ortholog); INVOLVED IN 'de novo' GDP-L-fucose biosynthetic process (ortholog); GDP-mannose metabolic process (ortholog); Notch signaling pathway (ortholog); PARTICIPA TES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; ASSOCIATED WITH open-angle glaucoma (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 17 | 32304029 | 32830708 | Rat | 139 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306711 | Gpa33 | glycoprotein A33 | ASSOCIATED WITH Latent Tuberculosis (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; bisphenol A | 13 | 80914119 | 80947738 | Rat | 36 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307254 | Gpalpp1 | GPALPP motifs containing 1 | INTERACTS WITH bisphenol A; paracetamol; 1,2-dimethylhydrazine (ortholog) | 15 | 57818490 | 57838723 | Rat | 36 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303304 | Gpank1 | G patch domain and ankyrin repeats 1 | ENCODES a protein that exhibits nucleic acid binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 20 | 3702309 | 3705476 | Rat | 42 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304889 | Gpr18 | G protein-coupled receptor 18 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN CD8-positive, alpha-beta intraepithelial T cell differentiation (ortholog); CD8-positive, gamma-delta intraepithelial T cell differentiation (ortholog); negative regulation of leukocyte chemotaxis (ortholog); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); membrane (inferred); INTERACTS WITH 1,2-dimethylhydrazine; acetamide; alpha-Zearalanol | 15 | 105404062 | 105407812 | Rat | 75 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310848 | Gpr22 | G protein-coupled receptor 22 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN cell projection organization (inferred); G protein-coupled receptor signaling pathway (inferred); ASSOCIATED WITH diabetes mellitus; FOUND IN plasma membrane; INTERACTS WITH bisphenol A; C60 fullerene; ketami ne | 6 | 54037998 | 54044994 | Rat | 45 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306745 | Gpr39 | G protein-coupled receptor 39 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN adult feeding behavior (ortholog); cellular response to zinc ion (ortholog); cholesterol homeostasis (ortholog); FOUND IN membrane (inferred); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxi ne; 6-propyl-2-thiouracil | 13 | 39667908 | 39879944 | Rat | 88 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306460 | Gpr63 | G protein-coupled receptor 63 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); FOUND IN receptor complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisph enol A | 5 | 43469112 | 43523840 | Rat | 45 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303014 | Gpsm3 | G-protein signaling modulator 3 | ENCODES a protein that exhibits GTPase regulator activity (inferred); INVOLVED IN positive regulation of cytokine production involved in inflammatory response (ortholog); positive regulation of inflammatory response (ortholog); positive regulation of leukocyte chemotaxis (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide | 20 | 4161730 | 4163591 | Rat | 59 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305433 | Gramd1c | GRAM domain containing 1C | ENCODES a protein that exhibits cholesterol binding (ortholog); cholesterol transfer activity (ortholog); INVOLVED IN cellular response to cholesterol (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); endoplasmic reticulum-plasma membrane contact site (ortholog); plasma membrane (ortho log); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 11 | 70139076 | 70224478 | Rat | 124 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309983 | Gramd4 | GRAM domain containing 4 | INVOLVED IN negative regulation of toll-like receptor 9 signaling pathway (ortholog); positive regulation of apoptotic process (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; atrazine | 7 | 119030225 | 119103875 | Rat | 76 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310649 | Grwd1 | glutamate-rich WD repeat containing 1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA replication origin binding (ortholog); histone binding (ortholog); INVOLVED IN DNA replication (ortholog); nucleosome assembly (ortholog); nucleosome disassembly (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); congenital diarrhea (ortholog); congenital diarrhea 14 (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; bisphenol A | 1 | 105437708 | 105443410 | Rat | 136 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305333 | Gsc2 | goosecoid homeobox 2 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleus (ortholog); INTERACTS WI TH bisphenol A; 1,2-dichloroethane (ortholog); 1,2-dimethylhydrazine (ortholog) | 11 | 96576424 | 96578412 | Rat | 39 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308047 | Gsx2 | GS homeobox 2 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN brain development (ortholog); central nervous system development (ortholog); forebrain dorsa l/ventral pattern formation (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Diencephalic-Mesencephalic Junction Dysplasia Syndrome 2 (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; Cuprizon; valproic acid | 14 | 33477968 | 33480320 | Rat | 70 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307435 | Gtf2ird2 | GTF2I repeat domain containing 2 | ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN transition between fast and slow fiber (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 12 | 28134199 | 28179089 | Rat | 65 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310025 | Gtpbp8 | GTP binding protein 8 | ENCODES a protein that exhibits GTP binding (inferred); metal ion binding (inferred); nucleotide binding (inferred); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene | 11 | 69451776 | 69461744 | Rat | 57 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305288 | Haus4 | HAUS augmin-like complex, subunit 4 | INVOLVED IN centrosome cycle (ortholog); spindle assembly (ortholog); FOUND IN centrosome (ortholog); HAUS complex (ortholog); mitotic spindle microtubule (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 31964555 | 31976853 | Rat | 116 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359238 | Hcst | hematopoietic cell signal transducer | ENCODES a protein that exhibits phosphatidylinositol 3-kinase binding (ortholog); protein-macromolecule adaptor activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN natural killer cell mediated cytotoxicity (ortholog); positive regulation of phosphatidylinositol 3-kinase/protein k inase B signal transduction (ortholog); protein phosphorylation (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,2',4,4'-Tetrabromodiphenyl ether | 1 | 94804429 | 94806661 | Rat | 74 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311839 | Hddc3 | HD domain containing 3 | INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 143708703 | 143711010 | Rat | 75 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308267 | Heatr3 | HEAT repeat containing 3 | INVOLVED IN erythrocyte maturation (ortholog); protein import into nucleus (ortholog); ribosomal large subunit biogenesis (ortholog); ASSOCIATED WITH Diamond-Blackfan anemia (ortholog); Diamond-Blackfan anemia 1 (ortholog); Diamond-Blackfan Anemia 21 (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; alpha-Zearalanol; amphetamine | 19 | 35065915 | 35103779 | Rat | 82 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1309823 | Hectd3 | HECT domain E3 ubiquitin protein ligase 3 | ENCODES a protein that exhibits syntaxin binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodiox ine; bisphenol A; Brodifacoum | 5 | 135706437 | 135715173 | Rat | 60 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309762 | Hectd4 | HECT domain E3 ubiquitin protein ligase 4 | ENCODES a protein that exhibits transferase activity (inferred); ubiquitin-protein transferase activity (inferred); INVOLVED IN glucose homeostasis (ortholog); glucose metabolic process (ortholog); ASSOCIATED WITH alcohol-induced mental disorder (ortholog); autism spectrum disorder (ortholog); coron ary artery disease (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 40800232 | 40991584 | Rat | 74 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1309820 | Hells | helicase, lymphoid specific | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); chromatin binding (ortholog); chromatin-protein adaptor activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); chromatin remodeling (ortholog); chromosomal DNA methylation mai ntenance following DNA replication (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN chromosome, centromeric region (ortholog); nucleus (ortholog); pericentric heterochromatin (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 246113580 | 246159230 | Rat | 237 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311843 | Hemk2 | HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine | ENCODES a protein that exhibits arsenite methyltransferase activity (ortholog); histone H4K12 methyltransferase activity (ortholog); protein methyltransferase activity (ortholog); INVOLVED IN arsonoacetate metabolic process (ortholog); methylation (ortholog); negative regulation of gene expression, epigenetic (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 11 | 40071017 | 40083463 | Rat | 98 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305697 | Hepacam2 | HEPACAM family member 2 | INVOLVED IN centrosome cycle (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN centrosome (ortholog); Golgi apparatus (ortholog); midbody (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 4 | 32400523 | 32435936 | Rat | 65 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311961 | Hlx | H2.0-like homeobox | ENCODES a protein that exhibits sequence-specific DNA binding (ortholog); INVOLVED IN animal organ development (ortholog); embryonic digestive tract morphogenesis (ortholog); enteric nervous system development (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH childhood-on set asthma (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide | 13 | 98811852 | 98817264 | Rat | 105 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305783 | Hmgxb4 | HMG-box containing 4 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN Wnt signaling pathway (inferred); FOUND IN NURF complex (ortholog); INTERACTS WITH acrylamide; bisphenol A; decabromodiphenyl ether | 19 | 13370559 | 13409306 | Rat | 68 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304928 | Hmx1 | H6 family homeobox 1 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ort holog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Craniofacial Abnormalities (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 14 | 79585840 | 79589626 | Rat | 75 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309179 | Hoxd1 | homeo box D1 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN embryonic skeletal system development (ortholog); neuron differentiation (ortholog); sensory perception of pain (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); Hyperalgesia (ortholog); Ovarian Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH amitriptyline; bisphenol A; copper atom | 3 | 80073041 | 80075180 | Rat | 97 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309797 | Hoxd12 | homeo box D12 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN embryonic digit morphogenesis (ortholog); pattern specification process (ortholog); skeletal system development (ortholog); ASSOCIATED WITH clubfoot (ortholog); Congenital Limb Deformities (ortholog ); melanoma (ortholog); FOUND IN transcription regulator complex (ortholog); INTERACTS WITH bisphenol A; paracetamol; vinclozolin | 3 | 79985106 | 79986227 | Rat | 51 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311747 | Hpf1 | histone PARylation factor 1 | ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); protein ADP-ribosyltransferase-substrate adaptor activity (ortholog); INVOLVED IN DNA damage response (ortholog); DNA repair (ortholog); DNA repair-dependent chromatin remodeling (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog); site of DNA damage (ortholog); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; bisphenol A | 16 | 34211971 | 34230551 | Rat | 77 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310548 | Hps3 | HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 | INVOLVED IN pigmentation (ortholog); ASSOCIATED WITH genetic disease (ortholog); hemorrhagic disease (ortholog); Hermansky-Pudlak syndrome (ortholog); FOUND IN BLOC-2 complex (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; acetamide | 2 | 104413618 | 104455091 | Rat | 92 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307959 | Hpse2 | heparanase 2 (inactive) | ENCODES a protein that exhibits heparan sulfate proteoglycan binding (ortholog); heparanase activity (ortholog); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell population proliferation (ortholog); PARTICIPATES IN glycosaminoglycan degradation pathway; ASSOCIATE D WITH CAKUT (ortholog); genetic disease (ortholog); urofacial syndrome (ortholog); FOUND IN extracellular matrix (ortholog); INTERACTS WITH acrolein; bisphenol A; methoxychlor | 1 | 251532149 | 252231316 | Rat | 48 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305385 | Hrob | homologous recombination factor with OB-fold | ENCODES a protein that exhibits single-stranded DNA binding (ortholog); INVOLVED IN DNA damage response (ortholog); DNA synthesis involved in DNA repair (ortholog); female gamete generation (ortholog); ASSOCIATED WITH Ovarian Dysgenesis 11 (ortholog); primary ovarian insufficiency (ortholog); FOUND IN site of DNA damage (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 87705846 | 87722635 | Rat | 79 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311331 | Hs1bp3 | HCLS1 binding protein 3 | ENCODES a protein that exhibits phosphatidylinositol binding (inferred); INVOLVED IN regulation of apoptotic process (ortholog); FOUND IN endoplasmic reticulum (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 6 | 36911864 | 36942126 | Rat | 62 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309218 | Hs6st1 | heparan sulfate 6-O-sulfotransferase 1 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (ortholog); INVOLVED IN angiogenesis (ortholog); heparan sulfate proteoglycan biosynthetic process (ortholog); labyrinthine layer blood vessel development (ortholog); PARTICIPATES IN heparan sulfate biosynthetic pathway; ASS OCIATED WITH hypogonadotropic hypogonadism 15 with or without anosmia (ortholog); hypogonadotropic hypogonadism 7 with or without anosmia (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amitrole; amphetamine | 9 | 45779402 | 45818583 | Rat | 100 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308433 | Hsdl1 | hydroxysteroid dehydrogenase like 1 | ENCODES a protein that exhibits steroid dehydrogenase activity (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; endosulfan | 19 | 64524435 | 64540527 | Rat | 63 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309122 | Hspb9 | heat shock protein family B (small) member 9 | ASSOCIATED WITH Developmental Disabilities (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 10 | 86141603 | 86142248 | Rat | 36 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310788 | Hvcn1 | hydrogen voltage-gated channel 1 | ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); voltage-gated monoatomic cation channel activity (ortholog); INVOLVED IN positive regulation of superoxide anion generation; regulation of intracellular pH; cellular response to pH (or tholog); ASSOCIATED WITH cerebral edema; decreased mean systemic arterial blood pressure; decreased systemic arterial blood pressure; ASSOCIATED WITH middle cerebral artery infarction; COVID-19 (ortholog); FOUND IN apical plasma membrane; membrane (ortholog); phagocytic vesicle membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; alpha-Zearalanol | 12 | 40001205 | 40030671 | Rat | 112 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308677 | Hykk | hydroxylysine kinase | ENCODES a protein that exhibits hydroxylysine kinase activity (ortholog); ASSOCIATED WITH chronic obstructive pulmonary disease (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzod ioxine | 8 | 64212043 | 64235809 | Rat | 78 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311857 | Iars2 | isoleucyl-tRNA synthetase 2, mitochondrial | ENCODES a protein that exhibits aminoacyl-tRNA deacylase activity (inferred); aminoacyl-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN aminoacyl-tRNA metabolism involved in translational fidelity (inferred); isoleucyl-tRNA aminoacylation (inferred); translation (inferred); ASSO CIATED WITH cataract (ortholog); CATARACTS, GROWTH HORMONE DEFICIENCY, SENSORY NEUROPATHY, SENSORINEURAL HEARING LOSS, AND SKELETAL DYSPLASIA (ortholog); Desbuquois dysplasia (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene | 13 | 99363035 | 99397068 | Rat | 111 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304553 | Ifi35 | interferon-induced protein 35 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN macrophage activation involved in immune response (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of non-canonical NF-kappaB signal transduction (ortholog); ASSOCIATED W ITH Experimental Liver Cirrhosis (ortholog); Human Influenza (ortholog); Spontaneous Abortions (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular space (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 10 | 86881270 | 86889523 | Rat | 146 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309400 | Ift20 | intraflagellar transport 20 | ENCODES a protein that exhibits opsin binding (ortholog); small GTPase binding (ortholog); INVOLVED IN protein localization to cilium; cardiac muscle cell differentiation (ortholog); centrosome localization (ortholog); FOUND IN acrosomal vesicle (ortholog); centriole (ortholog); centrosome (ortholog ); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 10 | 63930629 | 63936174 | Rat | 177 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307392 | Ift43 | intraflagellar transport 43 | INVOLVED IN cilium assembly (ortholog); intraciliary retrograde transport (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); connective tissue disease (ortholog); cranioectodermal dysplasia (ortholog); FOUND IN centriole (ortholog); cilium (ortholog); intercellular bridge (ortho log); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 6 | 111460689 | 111537224 | Rat | 78 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309717 | Ift88 | intraflagellar transport 88 | ENCODES a protein that exhibits kinesin binding (ortholog); INVOLVED IN response to silicon dioxide; animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH silicosis; asphyxiating thoracic dystrophy (ort holog); autosomal recessive polycystic kidney disease (ortholog); FOUND IN outer acrosomal membrane; trans-Golgi network; acrosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 15 | 35685678 | 35786875 | Rat | 171 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309730 | Iftap | intraflagellar transport associated protein | ENCODES a protein that exhibits intraciliary transport particle A binding (ortholog); INVOLVED IN acrosome reaction (ortholog); fertilization (ortholog); spermatogenesis (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN 9+0 non-motile cilium (ortholog); cytosol (ortholog); INTERACTS WITH (+) -schisandrin B; 17alpha-ethynylestradiol; atrazine | 3 | 108242105 | 108361607 | Rat | 60 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359642 | Igsf5 | immunoglobulin superfamily, member 5 | ENCODES a protein that exhibits PDZ domain binding (ortholog); INVOLVED IN cell-cell adhesion (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN bicellular tight junction (ortholog); cell surface (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acryl amide | 11 | 49155990 | 49198872 | Rat | 57 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305029 | Il27ra | interleukin 27 receptor subunit alpha | ENCODES a protein that exhibits interleukin-27 receptor activity (ortholog); INVOLVED IN defense response to Gram-positive bacterium (ortholog); negative regulation of cellular extravasation (ortholog); negative regulation of interleukin-17 production (ortholog); PARTICIPATES IN interleukin-27 signa ling pathway; ASSOCIATED WITH asthma (ortholog); Immunodeficiency 134 (Epstein-Barr virus-specific) (ortholog); pneumoconiosis (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; alpha-Zearalanol | 19 | 41014730 | 41026740 | Rat | 130 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305734 | Ilf2 | interleukin enhancer binding factor 2 | ENCODES a protein that exhibits DNA binding (ortholog); double-stranded RNA binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cyt osol (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol; 4-amino-2,6-dinitrotoluene | 2 | 178256927 | 178268773 | Rat | 110 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306825 | Imp3 | IMP U3 small nucleolar ribonucleoprotein 3 | INVOLVED IN ribosomal small subunit biogenesis (ortholog); rRNA processing (ortholog); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN Mpp10 complex (ortholog); nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3-chloropropane-1,2-d iol | 8 | 66235498 | 66236386 | Rat | 76 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306656 | Inca1 | inhibitor of CDK, cyclin A1 interacting protein 1 | ENCODES a protein that exhibits cyclin binding (ortholog); cyclin-dependent protein serine/threonine kinase inhibitor activity (ortholog); identical protein binding (ortholog); INVOLVED IN negative regulation of cell population proliferation (ortholog); negative regulation of cyclin-dependent protei n serine/threonine kinase activity (ortholog); positive regulation of apoptotic signaling pathway (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; trichloroethene; valproic acid | 10 | 55900610 | 55912975 | Rat | 53 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305292 | Incenp | inner centromere protein | ENCODES a protein that exhibits molecular function activator activity (ortholog); INVOLVED IN chromosome segregation (ortholog); mitotic cytokinesis (ortholog); ASSOCIATED WITH Familial Prostate Cancer (ortholog); melanoma (ortholog); nephronophthisis (ortholog); FOUND IN central element (ortholog); chromocenter (ortholog); chromosome, centromeric region (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 215945558 | 216017247 | Rat | 181 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310199 | Ino80c | INO80 complex subunit C | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (ortholog); Ino80 complex (ortholog); MLL1 complex ( ortholog); INTERACTS WITH bisphenol A; caffeine; flutamide | 18 | 15653508 | 15752455 | Rat | 96 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359572 | Ino80e | INO80 complex subunit E | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA-templated transcription (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH spondylocostal dysostosis 5 (ortholog); FOUND IN Ino80 complex (ortholo g); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH acrylamide; fenvalerate; lead diacetate | 1 | 190891315 | 190902902 | Rat | 72 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308908 | Ints1 | integrator complex subunit 1 | INVOLVED IN blastocyst growth (ortholog); embryo implantation (ortholog); inner cell mass cell proliferation (ortholog); ASSOCIATED WITH genetic disease (ortholog); neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies (ortholog); FOUND IN INTAC complex (ortholog); integrato r complex (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; bisphenol A; paracetamol | 12 | 19975166 | 19999893 | Rat | 85 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305547 | Ints2 | integrator complex subunit 2 | ENCODES a protein that exhibits ATP binding (inferred); DNA binding (inferred); DNA helicase activity (inferred); INVOLVED IN regulation of transcription elongation by RNA polymerase II (ortholog); RNA polymerase II transcription initiation surveillance (ortholog); snRNA processing (ortholog); ASSOC IATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); FOUND IN cytoplasm (ortholog); INTAC complex (ortholog); integrator complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amitrole | 10 | 71529021 | 71576529 | Rat | 89 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310592 | Ints8 | integrator complex subunit 8 | INVOLVED IN protein localization to chromatin (ortholog); regulation of transcription elongation by RNA polymerase II (ortholog); RNA polymerase II transcription initiation surveillance (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); NEURODEVELOPMENTAL DISORDER WITH CEREBELLAR HYPOPLASIA AN D SPASTICITY (ortholog); prostate cancer (ortholog); FOUND IN chromatin (ortholog); INTAC complex (ortholog); integrator complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3-chloropropane-1,2-diol | 5 | 29094475 | 29141874 | Rat | 76 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311539 | Ints9 | integrator complex subunit 9 | INVOLVED IN negative regulation of transforming growth factor beta receptor signaling pathway (ortholog); regulation of transcription elongation by RNA polymerase II (ortholog); RNA polymerase II transcription initiation surveillance (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INT AC complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; gentamycin; thioacetamide | 15 | 43376235 | 43460549 | Rat | 84 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359286 | Iqcm | IQ motif containing M | INTERACTS WITH sodium arsenite (ortholog) | 19 | 23076828 | 23307135 | Rat | 5 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311944 | Itfg2 | integrin alpha FG-GAP repeat containing 2 | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose starvation (ortholog); germinal center B cell differentiation (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN cytosol (ortholog); KICSTOR complex (ortholog); lysosomal membra ne (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 4 | 163371125 | 163384676 | Rat | 65 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307810 | Itgb1bp1 | integrin subunit beta 1 binding protein 1 | ENCODES a protein that exhibits GDP-dissociation inhibitor activity (ortholog); integrin binding (ortholog); kinase binding (ortholog); INVOLVED IN activation of protein kinase B activity (ortholog); blood vessel diameter maintenance (ortholog); blood vessel endothelial cell proliferation involved i n sprouting angiogenesis (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH bone development disease (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN cell periphery (ortholog); cytoplasm (ortholog); cytoskeleton (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; alpha-Zearalanol | 6 | 46549994 | 46564735 | Rat | 169 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304762 | Iws1 | interacts with SUPT6H, CTD assembly factor 1 | INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); in utero embryonic development (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,4-methylenedioxymethamphetamine | 18 | 23969352 | 24011560 | Rat | 104 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309108 | Jhy | junctional cadherin complex regulator | INVOLVED IN axoneme assembly (ortholog); brain development (ortholog); cell differentiation (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; lead diacetate; N-methyl-4-phenylpyridinium | 8 | 50173602 | 50230429 | Rat | 37 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305388 | Josd1 | Josephin domain containing 1 | ENCODES a protein that exhibits deubiquitinase activity (ortholog); INVOLVED IN cell motility (ortholog); endocytosis (ortholog); membrane biogenesis (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 7 | 113110709 | 113124632 | Rat | 76 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303127 | Kansl2 | KAT8 regulatory NSL complex subunit 2 | INVOLVED IN chromatin organization (inferred); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN cytosol (ortholog); histone acetyltransferase complex (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 7 | 131548062 | 131564876 | Rat | 82 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307242 | Kat2a | lysine acetyltransferase 2A | ENCODES a protein that exhibits chromatin binding; protein phosphatase binding; acetyltransferase activity (ortholog); INVOLVED IN alpha-tubulin acetylation; cellular response to nerve growth factor stimulus; cellular response to tumor necrosis factor; PARTICIPATES IN histone modification pathway; p 53 signaling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH hepatitis B (ortholog); lung non-small cell carcinoma (ortholog); neural tube defect (ortholog); FOUND IN chromatin; ATAC complex (ortholog); centrosome (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; amphetamine; bisphenol A | 10 | 86132535 | 86140877 | Rat | 245 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359147 | Kazn | kazrin, periplakin interacting protein | INVOLVED IN keratinization (inferred); FOUND IN cornified envelope (ortholog); cytosol (ortholog); desmosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 5 | 159675803 | 160666084 | Rat | 111 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310234 | Kbtbd4 | kelch repeat and BTB domain containing 4 | INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 97339500 | 97345599 | Rat | 53 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309887 | Kctd20 | potassium channel tetramerization domain containing 20 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN positive regulation of phosphorylation (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; gentamycin | 20 | 7017480 | 7034440 | Rat | 60 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303271 | Kdf1 | keratinocyte differentiation factor 1 | INVOLVED IN developmental growth (ortholog); epidermal cell differentiation (ortholog); establishment of skin barrier (ortholog); ASSOCIATED WITH anodontia (ortholog); ectodermal dysplasia 12 (ortholog); genetic disease (ortholog); FOUND IN cell cortex (ortholog); cell junction (ortholog); cell lead ing edge (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; benzo[a]pyrene | 5 | 151028152 | 151039753 | Rat | 84 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307443 | Kiaa0319 | KIAA0319 homolog | INVOLVED IN negative regulation of axon extension (ortholog); negative regulation of axon extension involved in regeneration (ortholog); negative regulation of dendrite development (ortholog); FOUND IN early endosome (ortholog); plasma membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisph enol A; endosulfan | 17 | 40587001 | 40654525 | Rat | 54 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359256 | Kiaa1191 | KIAA1191 homolog | ENCODES a protein that exhibits oxidoreductase activity (inferred); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); INTERACTS WITH bisphenol A; Brodifacoum; acrolein (ortholog) | 17 | 10054249 | 10066922 | Rat | 36 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310951 | Kiaa1958 | KIAA1958 homolog | ASSOCIATED WITH COVID-19 (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 5 | 79286708 | 79432859 | Rat | 33 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308211 | Klhdc1 | kelch domain containing 1 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (ortholog); FOUND IN Cul5-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTER ACTS WITH 6-propyl-2-thiouracil; acetamide; amphetamine | 6 | 93406226 | 93501475 | Rat | 60 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309792 | Klhdc10 | kelch domain containing 10 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN rescue of stalled cytosolic ribosome (ortholog); ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); FOUND IN Cul2-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); INTERACTS WITH acetamide; bisphenol A; furan | 4 | 59988710 | 60046518 | Rat | 66 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307105 | Klhdc3 | kelch domain containing 3 | ENCODES a protein that exhibits chromatin binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (orthol og); FOUND IN chromatin (ortholog); Cul2-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); INTERACTS WITH acrylamide; bis(2-ethylhexyl) phthalate; bisphenol A | 9 | 21799870 | 21806337 | Rat | 85 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309439 | Klhdc7a | kelch domain containing 7A | ASSOCIATED WITH Breast Neoplasms (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; amitrole | 5 | 157501740 | 157507843 | Rat | 83 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305132 | Klhdc8a | kelch domain containing 8A | INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 13 | 46287011 | 46296429 | Rat | 77 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307905 | Kntc1 | kinetochore associated 1 | INVOLVED IN mitotic spindle assembly checkpoint signaling (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytosol (ortholog); kinetochore microtubule (ortholog); RZZ complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 38429925 | 38500564 | Rat | 139 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359177 | Krt80 | keratin 80 | FOUND IN cytoplasm (ortholog); desmosome (ortholog); intermediate filament (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 7 | 134341951 | 134363872 | Rat | 110 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307504 | Krtap3-3 | keratin associated protein 3-3 | ENCODES a protein that exhibits structural molecule activity (inferred); FOUND IN cytosol (inferred); intermediate filament (inferred); keratin filament (inferred); INTERACTS WITH alpha-Zearalanol; atrazine; bisphenol A | 10 | 85007606 | 85007905 | Rat | 25 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308413 | Krtcap2 | keratinocyte associated protein 2 | ENCODES a protein that exhibits enzyme activator activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN protein N-linked glycosylation (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); oligosaccharyltransferase complex (ortholog); oligosaccharyltransferase complex A (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 2 | 176952167 | 176956163 | Rat | 100 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308719 | Ktn1 | kinectin 1 | ENCODES a protein that exhibits kinesin binding (inferred); INVOLVED IN microtubule-based movement (inferred); protein transport (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlo rodibenzodioxine; 2,4-dinitrotoluene | 15 | 23392570 | 23485061 | Rat | 119 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1305721 | L3hypdh | trans-L-3-hydroxyproline dehydratase | ENCODES a protein that exhibits hydro-lyase activity (ortholog); proline racemase activity (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,2',4,4',5,5'-hexachlorobiphenyl | 6 | 96372243 | 96383039 | Rat | 65 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304788 | Lactb | lactamase, beta | ENCODES a protein that exhibits identical protein binding; peptidase activity (ortholog); INVOLVED IN proteolysis (ortholog); regulation of lipid metabolic process (ortholog); ASSOCIATED WITH obesity (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6 -dinitrotoluene; aflatoxin B1 | 8 | 76452679 | 76469986 | Rat | 110 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307133 | Lamtor3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); kinase activator activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); intracellular protein localization (ortholog); positive regulation of M APK cascade (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN FNIP-folliculin RagC/D GAP (ortholog); late endosome (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,6-dinitrotoluene; amphetamine | 2 | 229084795 | 229097028 | Rat | 119 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309735 | Lamtor4 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); positive regulation of TOR signaling (ortholog); positive regulation of TORC1 signaling (ortholog); PARTICIPA TES IN mTOR signaling pathway; FOUND IN FNIP-folliculin RagC/D GAP (ortholog); lysosomal membrane (ortholog); lysosome (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 22372269 | 22376090 | Rat | 76 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304962 | Lars1 | leucyl-tRNA synthetase 1 | ENCODES a protein that exhibits aminoacyl-tRNA deacylase activity (ortholog); glutamine-tRNA ligase activity (ortholog); GTPase activator activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amino acid stimulus (ortholog); cellular response to L-leucine (ortholog); PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway; valine, leucine and isoleucine biosynthetic pathway; ASSOCIATED WITH infantile liver failure syndrome 1 (ortholog); microcephaly (ortholog); sensorineural hearing loss (ortholog); FOUND IN aminoacyl-tRNA synthetase multienzyme complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 18 | 34452567 | 34507030 | Rat | 161 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305829 | Lcmt2 | leucine carboxyl methyltransferase 2 | ENCODES a protein that exhibits methyltransferase activity (inferred); transferase activity (inferred); zinc ion binding (inferred); INVOLVED IN methylation (inferred); tRNA processing (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 3 | 128553707 | 128555831 | Rat | 68 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306747 | Lcn8 | lipocalin 8 | ENCODES a protein that exhibits small molecule binding (inferred); INVOLVED IN response to hormone (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 3,4-methylenedioxymethamphetamine; acrylamide; bisphenol A | 3 | 28866061 | 28869045 | Rat | 24 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311933 | Leg1 | liver enriched gene 1 | FOUND IN extracellular space (ortholog); INTERACTS WITH trichloroethene; (-)-demecolcine (ortholog); aflatoxin B1 (ortholog) | 1 | 30628501 | 30644590 | Rat | 21 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1304639 | Lig4 | DNA ligase 4 | ENCODES a protein that exhibits AMP binding; DNA ligase (ATP) activity; ATP binding (ortholog); INVOLVED IN cellular response to lithium ion; base-excision repair (ortholog); cell population proliferation (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; A SSOCIATED WITH colorectal cancer (ortholog); DNA ligase IV deficiency (ortholog); genetic disease (ortholog); FOUND IN condensed chromosome (ortholog); DNA ligase IV complex (ortholog); DNA-dependent protein kinase-DNA ligase 4 complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 16 | 86220345 | 86228930 | Rat | 198 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308792 | Lins1 | lines homolog 1 | INVOLVED IN cognition (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal recessive intellectual developmental disorder 27 (ortholog); genetic disease (ortholog); INTERACTS WITH amphetamine; bisphenol A; endosulfan | 1 | 129677815 | 129705399 | Rat | 40 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306208 | Lkaaear1 | LKAAEAR motif containing 1 | INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Cuprizon | 3 | 189190596 | 189192279 | Rat | 15 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308261 | Llph | LLP homolog, long-term synaptic facilitation factor | ENCODES a protein that exhibits basal RNA polymerase II transcription machinery binding (ortholog); INVOLVED IN dendrite extension (ortholog); positive regulation of dendritic spine development (ortholog); FOUND IN chromosome (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenz odioxine; bisphenol A; paracetamol | 7 | 57620925 | 57625924 | Rat | 64 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1302984 | Lmo7 | LIM domain 7 | ENCODES a protein that exhibits actinin binding; INVOLVED IN positive regulation of transcription by RNA polymerase II; ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); FOUND IN adherens junction; apical plasma membrane; actin cytoskeleton (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 15 | 84981689 | 85184554 | Rat | 193 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 11448581 | LOC108353077 | ral guanine nucleotide dissociation stimulator-like | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred) | 16 | 11128927 | 11131518 | Rat | 1 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1308435 | Loxl2 | lysyl oxidase-like 2 | ENCODES a protein that exhibits calcium ion binding (ortholog); copper ion binding (ortholog); oligosaccharide binding (ortholog); INVOLVED IN collagen fibril organization (ortholog); endothelial cell migration (ortholog); endothelial cell proliferation (ortholog); ASSOCIATED WITH autism spectrum di sorder (ortholog); Breast Neoplasms (ortholog); esophagus squamous cell carcinoma (ortholog); FOUND IN basement membrane; chromatin (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil | 15 | 51091547 | 51182843 | Rat | 236 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305779 | Lratd1 | LRAT domain containing 1 | INVOLVED IN cell morphogenesis (ortholog); cell motility (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide | 6 | 42646515 | 42650988 | Rat | 98 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308602 | Lrp11 | LDL receptor related protein 11 | ENCODES a protein that exhibits phosphoprotein binding (ortholog); INVOLVED IN multicellular organismal response to stress (ortholog); response to cold (ortholog); response to heat (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl- 2-thiouracil | 1 | 3868665 | 3928513 | Rat | 105 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305896 | Lrp2bp | Lrp2 binding protein | FOUND IN cytoplasm (inferred); INTERACTS WITH bisphenol A; cadmium dichloride; endosulfan | 16 | 52976005 | 53001952 | Rat | 23 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306575 | Lrpprc | leucine-rich pentatricopeptide repeat containing | ENCODES a protein that exhibits actin filament binding (ortholog); beta-tubulin binding (ortholog); mRNA binding (ortholog); INVOLVED IN mitochondrial mRNA polyadenylation (ortholog); negative regulation of mitochondrial mRNA catabolic process (ortholog); negative regulation of mitochondrial RNA cat abolic process (ortholog); PARTICIPATES IN CRM1 export pathway; ASSOCIATED WITH cytochrome-c oxidase deficiency disease (ortholog); epilepsy (ortholog); French Canadian Leigh disease (ortholog); FOUND IN condensed nuclear chromosome (ortholog); cytoplasm (ortholog); cytoskeleton (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aconitine | 6 | 15612638 | 15695113 | Rat | 189 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311716 | Lrrc2 | leucine rich repeat containing 2 | INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 8 | 119814514 | 119847587 | Rat | 63 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311221 | Lrrc41 | leucine rich repeat containing 41 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN protein ubiquitination (inferred); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; bispheno l A | 5 | 134791256 | 134812177 | Rat | 84 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309453 | Lrrc71 | leucine rich repeat containing 71 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 2 | 175492682 | 175505334 | Rat | 37 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311690 | Lrrc8a | leucine rich repeat containing 8 VRAC subunit A | ENCODES a protein that exhibits volume-sensitive anion channel activity; cyclic-GMP-AMP transmembrane transporter activity (ortholog); identical protein binding (ortholog); INVOLVED IN aspartate transmembrane transport; response to osmotic stress; taurine transmembrane transport; ASSOCIATED WITH aga mmaglobulinemia (ortholog); agammaglobulinemia 5 (ortholog); FOUND IN cell surface (ortholog); lysosomal membrane (ortholog); membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 33902299 | 33934989 | Rat | 189 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306585 | Lrrc8c | leucine rich repeat containing 8 VRAC subunit C | ENCODES a protein that exhibits volume-sensitive anion channel activity; INVOLVED IN aspartate transmembrane transport; cellular response to osmotic stress; taurine transmembrane transport; ASSOCIATED WITH multiple sclerosis (ortholog); TIMES Syndrome (ortholog); FOUND IN monoatomic ion channel comp lex; cytoplasm (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil | 14 | 4528721 | 4621259 | Rat | 163 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306133 | Lsp1 | lymphocyte-specific protein 1 | ENCODES a protein that exhibits actin binding (inferred); INVOLVED IN cellular response to interleukin-7 (ortholog); chemotaxis (ortholog); defense response (ortholog); PARTICIPATES IN tuberculosis pathway; ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); calcinosis (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate | 1 | 207044157 | 207077891 | Rat | 153 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309448 | Ltbr | lymphotoxin beta receptor | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); myeloid dendritic cell differentiation (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortho log); PARTICIPATES IN cytokine mediated signaling pathway; tuberculosis pathway; ASSOCIATED WITH autosomal recessive pseudohypoaldosteronism type 1 (ortholog); Drug-Related Side Effects and Adverse Reactions (ortholog); malaria (ortholog); FOUND IN Golgi apparatus (ortholog); plasma membrane (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 159795115 | 159801571 | Rat | 137 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304637 | Lto1 | LTO1 maturation factor of ABCE1 | INVOLVED IN protein maturation (ortholog); ribosomal large subunit biogenesis (ortholog); translational initiation (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A | 1 | 209502900 | 209510237 | Rat | 60 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308059 | Lurap1l | leucine rich adaptor protein 1-like | INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (inferred); ASSOCIATED WITH esophageal atresia/tracheoesophageal fistula (ortholog); Experimental Liver Cirrhosis (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-naphthyl isothiocyanate; 2,3,7,8-t etrachlorodibenzodioxine | 5 | 100402921 | 100455479 | Rat | 112 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309253 | Lzic | leucine zipper and CTNNBIP1 domain containing | ENCODES a protein that exhibits beta-catenin binding (inferred); INVOLVED IN response to ionizing radiation; ASSOCIATED WITH osteosarcoma; INTERACTS WITH 2,4-dinitrotoluene; 3-chloropropane-1,2-diol; bisphenol A | 5 | 165211359 | 165224569 | Rat | 51 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309100 | Lztr1 | leucine zipper like post translational regulator 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN negative regulation of Ras protein signal transduction (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); protein ubiquitin ation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); bladder exstrophy (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); endomembrane system (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; endosulfan; methimazole | 11 | 96991956 | 97008127 | Rat | 123 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309838 | Macc1 | MET transcriptional regulator MACC1 | INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH cervical cancer (ortholog); COVID-19 (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred); INTERACTS WITH bisphenol A; trichloroethene; 1,2-dimethylhydrazine (or tholog) | 6 | 146495544 | 146574254 | Rat | 71 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309175 | Mad2l1bp | MAD2L1 binding protein | INVOLVED IN deactivation of mitotic spindle assembly checkpoint (ortholog); regulation of exit from mitosis (ortholog); ASSOCIATED WITH Zellweger syndrome (ortholog); FOUND IN cytoplasm (ortholog); nuclear membrane (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2 ,4-dinitrotoluene; acrylamide | 9 | 22329699 | 22334024 | Rat | 64 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1549729 | Magix | MAGI family member, X-linked | INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether | X | 17496092 | 17504370 | Rat | 55 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305785 | Manba | mannosidase beta | ENCODES a protein that exhibits beta-mannosidase activity; D-mannose binding; hydrolase activity (ortholog); INVOLVED IN glycoprotein catabolic process (ortholog); ASSOCIATED WITH beta-mannosidosis (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether | 2 | 226583968 | 226676520 | Rat | 114 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309438 | Map3k7 | mitogen activated protein kinase kinase kinase 7 | ENCODES a protein that exhibits ATP binding; DNA-binding transcription factor binding; histone kinase activity; INVOLVED IN cellular response to angiotensin; cellular response to hypoxia; cellular response to transforming growth factor beta stimulus; PARTICIPATES IN p38 MAPK signaling pathway; Bone morphogenetic proteins signaling pathway; c-Jun N-terminal kinases MAPK signaling pathway; ASSOCIATED WITH arteriosclerosis; Brain Hypoxia-Ischemia; Brain Injuries; FOUND IN ATAC complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 5 | 51149524 | 51212012 | Rat | 416 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305322 | Map4k4 | mitogen-activated protein kinase kinase kinase kinase 4 | ENCODES a protein that exhibits ATP binding (ortholog); creatine kinase activity (ortholog); MAP kinase kinase kinase kinase activity (ortholog); INVOLVED IN negative regulation of insulin secretion involved in cellular response to glucose stimulus; negative regulation of neuron projection developme nt; negative regulation of neuron projection regeneration; PARTICIPATES IN ceramide signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH arteriovenous malformations of the brain (ortholog); colorectal cancer (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); focal adhesion (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 49696573 | 49822353 | Rat | 232 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311455 | Mapk1ip1l | mitogen-activated protein kinase 1 interacting protein 1-like | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 15 | 23024757 | 23051189 | Rat | 56 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305363 | Mapkap1 | MAPK associated protein 1 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); molecular adaptor activity (ortholog); phosphatidic acid binding (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); negative regulation of Ras protein signal transduction (ortholog); positive regulat ion of peptidyl-serine phosphorylation (ortholog); PARTICIPATES IN mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog); early endosome (ortholog); INTERACTS WITH 2,4-dinitrotoluene; atrazine; bisphenol A | 3 | 38113268 | 38315913 | Rat | 142 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307578 | Mapkbp1 | mitogen activated protein kinase binding protein 1 | INVOLVED IN negative regulation of canonical NF-kappaB signal transduction (ortholog); negative regulation of defense response to bacterium (ortholog); negative regulation of interleukin-8 production (ortholog); ASSOCIATED WITH genetic disease (ortholog); nephronophthisis 20 (ortholog); FOUND IN cyt oplasm (ortholog); mitotic spindle pole (ortholog); nucleolus (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; acrylamide; amphetamine | 3 | 127401612 | 127452152 | Rat | 80 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308993 | Marchf7 | membrane associated ring-CH-type finger 7 | ENCODES a protein that exhibits enzyme binding (ortholog); MDM2/MDM4 family protein binding (ortholog); ubiquitin binding (ortholog); INVOLVED IN negative regulation of cilium assembly (ortholog); negative regulation of DNA damage response, signal transduction by p53 class mediator (ortholog); negat ive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ortholog); FOUND IN centrosome (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 65090640 | 65128768 | Rat | 110 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305321 | Mars1 | methionyl-tRNA synthetase 1 | ENCODES a protein that exhibits methionine-tRNA ligase activity (ortholog); INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to platelet-derived growth factor stimulus (ortholog); homocysteine metabolic process (ortholog); PARTICIPATES IN glycine N-meth yltransferase deficiency pathway; homocystinuria pathway; hypermethioninemia pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease axonal type 2U (ortholog); hereditary spastic paraplegia 70 (ortholog); FOUND IN aminoacyl-tRNA synthetase multienzyme complex; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 3-chloropropane-1,2-diol | 7 | 65006456 | 65023880 | Rat | 157 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311527 | Mars2 | methionyl-tRNA synthetase 2, mitochondrial | ENCODES a protein that exhibits methionine-tRNA ligase activity (ortholog); INVOLVED IN methionyl-tRNA aminoacylation (ortholog); PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway; selenoamino acid metabolic pathway; ASSOCIATED WITH combined oxidative phosphorylation deficiency 25 (ortholog); spas tic ataxia 3 (ortholog); FOUND IN mitochondrial matrix (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,4-dinitrotoluene | 9 | 64214935 | 64228408 | Rat | 92 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1309186 | Mastl | microtubule associated serine/threonine kinase-like | ENCODES a protein that exhibits kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN female meiosis II (ortholog); G2/M transition of mitotic cell cycle (ortholog); meiotic chromosome condensation (ortholog); ASSOC IATED WITH thrombocytopenia (ortholog); Thrombocytopenia 2 (ortholog); FOUND IN centrosome (ortholog); cleavage furrow (ortholog); meiotic spindle (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 17 | 90158592 | 90195550 | Rat | 122 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305884 | Med13l | mediator complex subunit 13L | ENCODES a protein that exhibits transcription coactivator activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH Au-Kline Syndrome (ortholog); autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN mediator complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 43468556 | 43665819 | Rat | 142 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311926 | Med19 | mediator complex subunit 19 | ENCODES a protein that exhibits transcription coregulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH intellectual disability (ortholog); FOUND IN mediator complex (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 90168829 | 90179351 | Rat | 70 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309524 | Med26 | mediator complex subunit 26 | ENCODES a protein that exhibits transcription coregulator activity (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN mediator complex (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlor odibenzodioxine; amitrole; cadmium dichloride | 16 | 17333770 | 17384797 | Rat | 77 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311009 | Med29 | mediator complex subunit 29 | PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN mediator complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; finasteride; flutamide | 1 | 92805505 | 92810908 | Rat | 50 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359271 | Metrnl | meteorin-like, glial cell differentiation regulator | ENCODES a protein that exhibits hormone activity (ortholog); INVOLVED IN brown fat cell differentiation (ortholog); energy homeostasis (ortholog); fat cell differentiation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); glucose intolerance (ortholog); Insulin Resistance (ortholo g); FOUND IN extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 10 | 107462148 | 107476143 | Rat | 170 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308812 | Mfhas1 | multifunctional ROCO family signaling regulator 1 | ENCODES a protein that exhibits GTP binding (ortholog); protein phosphatase 2A binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN defense response (ortholog); erythrocyte differentiation (ortholog); inflammatory response (ortholog); ASSOCIATED WITH fibrous histiocytoma (ort holog); malignant fibrous histiocytoma (ortholog); myoepithelioma (ortholog); FOUND IN cytoplasm (ortholog); cytoskeleton (ortholog); lysosome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 63248833 | 63336441 | Rat | 169 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309629 | Midn | midnolin | ENCODES a protein that exhibits kinase binding; molecular adaptor activity (ortholog); INVOLVED IN negative regulation of glucokinase activity; negative regulation of insulin secretion; proteasomal ubiquitin-independent protein catabolic process (ortholog); ASSOCIATED WITH long QT syndrome (ortholog ); FOUND IN nucleolus; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; glafenine | 7 | 10198761 | 10210563 | Rat | 115 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359135 | Mink1 | misshapen-like kinase 1 | ENCODES a protein that exhibits ATP binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN chemical synaptic transmission; dendrite morphogenesis; neuron cellular homeostasis; FOUND IN glutamatergic synapse; postsynapse; cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetr achlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 10 | 55776879 | 55829406 | Rat | 133 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307700 | Mitd1 | microtubule interacting and trafficking domain containing 1 | ENCODES a protein that exhibits identical protein binding (ortholog); phosphatidylinositol binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN midbody abscission (ortholog); mitotic cytokinesis (ortholog); multivesicular body sorting pathway (ortholog); FOUND IN membrane (ort holog); midbody (ortholog); INTERACTS WITH acrylamide; bisphenol A; cadmium dichloride | 9 | 47609743 | 47621033 | Rat | 65 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310011 | Mixl1 | Mix paired-like homeobox 1 | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cell migration involved in gastrulation (ortholog); digestive tract development (ortholog); endoderm development (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 13 | 94953907 | 94957938 | Rat | 115 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308814 | Mkks | MKKS centrosomal shuttling protein | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN artery smooth muscle contraction (ortholog); brain morphogenesis (ortholog); cartilage development (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Bardet-Biedl sy ndrome 1 (ortholog); Bardet-Biedl Syndrome 2/6, Digenic (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); cytoplasm (ortholog); INTERACTS WITH bisphenol A; cadmium atom; cadmium dichloride | 3 | 144654563 | 144672831 | Rat | 153 | PANTHER | gene, protein-coding, REVIEWED [RefSeq] |
| 1310733 | Mlph | melanophilin | ENCODES a protein that exhibits actin binding (ortholog); microtubule plus-end binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN melanocyte differentiation (ortholog); melanosome localization (ortholog); pigmentation (ortholog); ASSOCIATED WITH alopecia (ortholog); genetic disea se (ortholog); Griscelli syndrome type 3 (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); dendrite (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; acrylamide | 9 | 98955036 | 98990566 | Rat | 137 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304693 | Mms22l | MMS22-like, DNA repair protein | ENCODES a protein that exhibits single-stranded DNA binding (ortholog); INVOLVED IN double-strand break repair via homologous recombination (ortholog); protein localization to chromatin (ortholog); replication fork processing (ortholog); FOUND IN FACT complex (ortholog); MCM complex (ortholog); nucl ear replication fork (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 42994382 | 43110371 | Rat | 100 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307336 | Morn4 | MORN repeat containing 4 | INVOLVED IN response to axon injury (ortholog); FOUND IN cytoplasm (ortholog); filopodium tip (ortholog); stereocilium tip (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 1 | 250837639 | 250847943 | Rat | 67 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307739 | Morn5 | MORN repeat containing 5 | FOUND IN sperm flagellum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 3 | 39799531 | 39827482 | Rat | 39 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304735 | Mov10l1 | Mov10 like RNA helicase 1 | ENCODES a protein that exhibits piRNA binding (ortholog); RNA helicase activity (ortholog); INVOLVED IN germ cell development (ortholog); male meiosis I (ortholog); male meiotic nuclear division (ortholog); ASSOCIATED WITH azoospermia (ortholog); male infertility (ortholog); spermatogenic failure 3 (ortholog); FOUND IN P granule (ortholog); pi-body (ortholog); INTERACTS WITH bisphenol A; indole-3-methanol; methoxychlor | 7 | 121949743 | 122015042 | Rat | 63 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303269 | Mpig6b | megakaryocyte and platelet inhibitory receptor G6b | ENCODES a protein that exhibits heparin binding (inferred); INVOLVED IN blood coagulation (ortholog); erythrocyte differentiation (ortholog); integrin-mediated signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); hemorrhagic disease (ortholog); Thrombocytopenia, Anemia, and Myel ofibrosis (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 20 | 3761832 | 3765679 | Rat | 62 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309873 | Mrap2 | melanocortin 2 receptor accessory protein 2 | ENCODES a protein that exhibits corticotropin hormone receptor binding (ortholog); identical protein binding (ortholog); signaling receptor regulator activity (ortholog); INVOLVED IN energy homeostasis (ortholog); energy reserve metabolic process (ortholog); feeding behavior (ortholog); PARTICIPATES IN melanocortin system pathway; ASSOCIATED WITH obesity (ortholog); FOUND IN endoplasmic reticulum (ortholog); plasma membrane (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; bisphenol A | 8 | 96968239 | 97024581 | Rat | 108 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307789 | Mri1 | methylthioribose-1-phosphate isomerase 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN amino acid biosynthetic process (inferred); L-methionine salvage from methylthioadenosine (inferred); methionine biosynthetic process (inferred); PARTICIPATES IN cysteine and methionine metabolic pathway; ASSOCIATED WI TH neurodegenerative disease (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; endosulfan; flutamide | 19 | 40812114 | 40819846 | Rat | 79 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306375 | Mrpl36 | mitochondrial ribosomal protein L36 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine ; 3-chloropropane-1,2-diol; bisphenol A | 1 | 31794025 | 31797446 | Rat | 69 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304913 | Mrpl45 | mitochondrial ribosomal protein L45 | ENCODES a protein that exhibits structural constituent of ribosome (ortholog); INVOLVED IN mitochondrial translation (ortholog); ASSOCIATED WITH atherosclerosis (ortholog); FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzod ioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 82805039 | 82816862 | Rat | 81 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308008 | Mrpl50 | mitochondrial ribosomal protein L50 | FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH alpha-Zearalanol; amitrole; bisphenol A | 5 | 68662933 | 68668087 | Rat | 96 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309297 | Mrpl52 | mitochondrial ribosomal protein L52 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN mitochondrial translation (inferred); FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlo rodibenzodioxine | 15 | 31852927 | 31856160 | Rat | 72 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306709 | Mrpl53 | mitochondrial ribosomal protein L53 | FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 4 | 117173043 | 117173933 | Rat | 63 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305694 | Mrpl54 | mitochondrial ribosomal protein L54 | FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 7 | 9103525 | 9106045 | Rat | 86 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308161 | Mrpl55 | mitochondrial ribosomal protein L55 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 44488252 | 44491401 | Rat | 55 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306014 | Mrps24 | mitochondrial ribosomal protein S24 | FOUND IN mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 14 | 84798649 | 84802777 | Rat | 65 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305623 | Mrps34 | mitochondrial ribosomal protein S34 | ENCODES a protein that exhibits structural constituent of ribosome (ortholog); INVOLVED IN mitochondrial translation (ortholog); ASSOCIATED WITH combined oxidative phosphorylation deficiency 32 (ortholog); genetic disease (ortholog); Leigh disease (ortholog); FOUND IN mitochondrion (ortholog); INTER ACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 14420543 | 14421674 | Rat | 86 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308318 | Mrps5 | mitochondrial ribosomal protein S5 | ENCODES a protein that exhibits RNA binding (inferred); structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); FOUND IN mitochondrial small ribosomal subunit (ortholog); mitochondrion (ortho log); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 3 | 135274333 | 135290577 | Rat | 76 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306558 | Mrps9 | mitochondrial ribosomal protein S9 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 9 | 52605678 | 52664499 | Rat | 60 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311709 | Mrto4 | MRT4 homolog, ribosome maturation factor | INVOLVED IN ribosomal large subunit assembly (inferred); ribosome biogenesis (inferred); FOUND IN nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 156884985 | 156891738 | Rat | 119 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309408 | Mss51 | MSS51 mitochondrial translational activator | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 15 | 3855094 | 3868614 | Rat | 48 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311836 | Mterf2 | mitochondrial transcription termination factor 2 | ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN DNA-templated transcription (inferred); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN mitochondrial nucleoid (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachl orodibenzofuran | 7 | 20485901 | 20495979 | Rat | 73 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304936 | Mtfr1 | mitochondrial fission regulator 1 | INVOLVED IN aerobic respiration (ortholog); mitochondrial fission (ortholog); mitochondrion organization (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione; 4,4'-diaminodiphenylmethane | 2 | 103594458 | 103629697 | Rat | 94 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306876 | Mthfs | methenyltetrahydrofolate synthetase | ENCODES a protein that exhibits 5-formyltetrahydrofolate cyclo-ligase activity (ortholog); ATP binding (ortholog); folic acid binding (ortholog); INVOLVED IN folic acid catabolic process (ortholog); glutamate metabolic process (ortholog); tetrahydrofolate interconversion (ortholog); PARTICIPATES IN folate metabolic pathway; hereditary folate malabsorption pathway; methotrexate pharmacodynamics pathway; ASSOCIATED WITH cleft lip (ortholog); cleft palate (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial matrix (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 2,4-dinitrotoluene | 8 | 98609410 | 98681901 | Rat | 84 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308388 | Mttp | microsomal triglyceride transfer protein | ENCODES a protein that exhibits apolipoprotein binding; cholesterol transfer activity; lipid transporter activity; INVOLVED IN cholesterol homeostasis; lipid transport; lipoprotein metabolic process; ASSOCIATED WITH familial hyperlipidemia; abdominal obesity-metabolic syndrome 1 (ortholog); abetalip oproteinemia (ortholog); FOUND IN basolateral plasma membrane; brush border membrane; microvillus membrane; INTERACTS WITH (R)-carnitine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 2 | 229286501 | 229327650 | Rat | 381 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304865 | Muc20 | mucin 20, cell surface associated | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN hepatocyte growth factor receptor signaling pathway (ortholog); positive regulation of MAPK cascade (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); IgA glomerulonephritis (ortholog); lupus nephritis (ortho log); FOUND IN basal plasma membrane (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; amphetamine; bisphenol A | 11 | 81492844 | 81506571 | Rat | 54 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309709 | Mvb12b | multivesicular body subunit 12B | ENCODES a protein that exhibits lipid binding (ortholog); ubiquitin binding (ortholog); INVOLVED IN regulation of epidermal growth factor receptor signaling pathway (ortholog); PARTICIPATES IN endocytosis pathway; FOUND IN cytosol (ortholog); early endosome (ortholog); ESCRT I complex (ortholog); IN TERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 3 | 37431636 | 37590276 | Rat | 96 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1312048 | Mycbp2 | MYC binding protein 2 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); identical protein binding (ortholog); small GTPase binding (ortholog); INVOLVED IN branchiomotor neuron axon guidance (ortholog); cell morphogenesis involved in neuron differentiation (ortholog); central nervous s ystem projection neuron axonogenesis (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 26 (ortholog); colon cancer (ortholog); Developmental Disabilities (ortholog); FOUND IN axon (ortholog); microtubule cytoskeleton (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 15 | 86352061 | 86590126 | Rat | 178 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359237 | Myg1 | MYG1 exonuclease | ENCODES a protein that exhibits 3'-5'-RNA exonuclease activity (ortholog); INVOLVED IN locomotory exploration behavior (ortholog); mitochondrial RNA metabolic process (ortholog); mRNA processing (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); nucleolus (ortholog); INT ERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; aconitine | 7 | 135335364 | 135342567 | Rat | 89 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310915 | Mylk | myosin light chain kinase | ENCODES a protein that exhibits enzyme binding (ortholog); myosin light chain kinase activity (ortholog); scaffold protein binding (ortholog); INVOLVED IN regulation of synaptic vesicle endocytosis; aorta smooth muscle tissue morphogenesis (ortholog); bleb assembly (ortholog); PARTICIPATES IN acebut olol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); adult respiratory distress syndrome (ortholog); allergic disease (ortholog); FOUND IN synapse; actin cytoskeleton (ortholog); cell-cell junction (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 1,3-dinitrobenzene | 11 | 79288243 | 79535450 | Rat | 425 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 11426996 | Mymx | myomixer, myoblast fusion factor | INVOLVED IN myoblast fusion (ortholog); myoblast fusion involved in skeletal muscle regeneration (ortholog); plasma membrane fusion (ortholog); ASSOCIATED WITH Carey-Fineman-Ziter syndrome 2 (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); Golgi membrane (ortholog); plasma membrane (o rtholog); INTERACTS WITH 1,4-dichlorobenzene (ortholog); chlorpyrifos (ortholog); Moniliformin (ortholog) | 9 | 22894524 | 22895701 | Rat | 28 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308356 | N4bp3 | Nedd4 binding protein 3 | INVOLVED IN nervous system development (inferred); FOUND IN cytoplasmic vesicle (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 10 | 36400053 | 36407609 | Rat | 71 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307713 | Naa20 | N(alpha)-acetyltransferase 20, NatB catalytic subunit | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); protein N-terminal-methionine acetyltransferase activity (inferred); INVOLVED IN N-terminal peptidyl-aspartic acid acetylation (ortholog); N-ter minal peptidyl-glutamic acid acetylation (ortholog); N-terminal peptidyl-glutamine acetylation (ortholog); ASSOCIATED WITH autosomal recessive intellectual developmental disorder 73 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3H-1,2-dithiole-3-thione | 3 | 153775351 | 153790129 | Rat | 85 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306802 | Naf1 | nuclear assembly factor 1 ribonucleoprotein | ENCODES a protein that exhibits identical protein binding (ortholog); RNA binding (ortholog); telomerase RNA binding (ortholog); INVOLVED IN positive regulation of telomere maintenance via telomerase (ortholog); positive regulation of telomere maintenance via telomere lengthening (ortholog); ribosom e biogenesis (ortholog); ASSOCIATED WITH melanoma (ortholog); pulmonary fibrosis (ortholog); Pulmonary Fibrosis and/or Bone Marrow Failure Syndrome, Telomere-Related, 7 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 16 | 27604228 | 27634963 | Rat | 93 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311943 | Nans | N-acetylneuraminate synthase | ENCODES a protein that exhibits N-acylneuraminate-9-phosphate synthase activity (ortholog); INVOLVED IN CMP-N-acetylneuraminate biosynthetic process (ortholog); N-acetylneuraminate biosynthetic process (ortholog); N-acetylneuraminate metabolic process (ortholog); PARTICIPATES IN amino sugar metaboli c pathway; french type sialuria pathway; sialic acid storage disease pathway; ASSOCIATED WITH bone development disease (ortholog); Desbuquois dysplasia (ortholog); Developmental Disabilities (ortholog); FOUND IN cytosol; nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; alpha-Zearalanol; bisphenol A | 5 | 65575970 | 65593164 | Rat | 141 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1302945 | Naprt | nicotinate phosphoribosyltransferase | ENCODES a protein that exhibits nicotinate phosphoribosyltransferase activity; INVOLVED IN NAD+ biosynthetic process; NAD+ biosynthetic process via the salvage pathway (ortholog); response to oxidative stress (ortholog); PARTICIPATES IN nicotinamide adenine dinucleotide biosynthesis, the salvage pat hway; monoterpenoid biosynthetic pathway; niacin metabolic pathway; FOUND IN cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene | 7 | 109457328 | 109460817 | Rat | 122 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359609 | Nasp | nuclear autoantigenic sperm protein | ENCODES a protein that exhibits histone binding (ortholog); histone chaperone activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN male gonad development; response to testosterone; blastocyst development (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH Female Infertility (ortholog); ovarian cancer (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 135294599 | 135319992 | Rat | 192 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305932 | Nccrp1 | NCCRP1, F-box associated domain containing | INVOLVED IN positive regulation of cell population proliferation (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; atrazine; bisphenol A | 1 | 92962618 | 92966155 | Rat | 53 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311323 | Nckipsd | NCK interacting protein with SH3 domain | INVOLVED IN regulation of postsynapse assembly; positive regulation of neuron projection development (ortholog); FOUND IN glutamatergic synapse; postsynapse; COP9 signalosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 8 | 118390121 | 118401121 | Rat | 75 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309046 | Ncoa1 | nuclear receptor coactivator 1 | ENCODES a protein that exhibits nuclear estrogen receptor binding; nuclear receptor binding; nuclear retinoic acid receptor binding; INVOLVED IN cellular response to hormone stimulus; cerebellum development; cerebral cortex development; PARTICIPATES IN aldosterone signaling pathway; androgen signali ng pathway; cortisol signaling pathway; ASSOCIATED WITH hypothyroidism; breast carcinoma (ortholog); Breast Neoplasms (ortholog); FOUND IN chromatin (ortholog); protein-containing complex (ortholog); transcription regulator complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 32952090 | 33229829 | Rat | 327 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311080 | Ndnf | neuron-derived neurotrophic factor | ENCODES a protein that exhibits glycosaminoglycan binding (ortholog); heparin binding (ortholog); INVOLVED IN angiogenesis (ortholog); cellular response to fibroblast growth factor stimulus (ortholog); cellular response to hypoxia (ortholog); ASSOCIATED WITH endometriosis (ortholog); Hypogonadotropi c Hypogonadism 25 with Anosmia (ortholog); FOUND IN extracellular matrix (ortholog); extracellular region (ortholog); extracellular space (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; all-trans-retinoic acid | 4 | 96274147 | 96311624 | Rat | 87 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303292 | Ndufa11 | NADH:ubiquinone oxidoreductase subunit A11 | INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (inferred); respiratory electron transport chain (inferred); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; ASSOCIATED WITH communication disorder (ortholog); mitochondrial complex I deficiency (ortholog); nuclear type mitochondrial complex I deficiency 1 (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 9 | 1637614 | 1641673 | Rat | 96 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304597 | Ndufa7 | NADH:ubiquinone oxidoreductase subunit A7 | INVOLVED IN ATP synthesis coupled electron transport (inferred); respiratory electron transport chain (inferred); vesicle-mediated transport (inferred); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A | 7 | 15311446 | 15324226 | Rat | 102 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309829 | Ndufaf5 | NADH:ubiquinone oxidoreductase complex assembly factor 5 | ENCODES a protein that exhibits methyltransferase activity (inferred); oxidoreductase activity (inferred); S-adenosylmethionine-dependent methyltransferase activity (inferred); INVOLVED IN mitochondrial respiratory chain complex I assembly (ortholog); ASSOCIATED WITH genetic disease (ortholog); Lebe r plus disease (ortholog); Leigh disease (ortholog); FOUND IN matrix side of mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; aconitine | 3 | 147961612 | 147991128 | Rat | 57 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310782 | Ndufb10 | NADH:ubiquinone oxidoreductase subunit B10 | INVOLVED IN respiratory electron transport chain (inferred); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; ASSOCIATED WITH mitochondrial complex I deficiency (ortholog); nuclear type mitochondrial complex I deficiency 35 (ortholog); FOU ND IN mitochondrial inner membrane (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 10 | 14253805 | 14255966 | Rat | 117 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308130 | Ndufb2 | NADH:ubiquinone oxidoreductase subunit B2 | INVOLVED IN respiratory electron transport chain (inferred); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WIT H 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; bisphenol A | 4 | 69334307 | 69341394 | Rat | 119 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309129 | Ndufb8 | NADH:ubiquinone oxidoreductase subunit B8 | INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (inferred); respiratory electron transport chain (inferred); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; ASSOCIATED WITH acute kidney failure; Kidney Reperfusion Injury; Sepsis; FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 253357878 | 253362936 | Rat | 164 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311081 | Ndufs5 | NADH:ubiquinone oxidoreductase subunit S5 | INVOLVED IN mitochondrial respiratory chain complex I assembly (ortholog); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol | 5 | 141258828 | 141264552 | Rat | 109 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309505 | Nectin2 | nectin cell adhesion molecule 2 | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN acrosome assembly (ortholog); cellular anatomical entity morphogenesis (ortholog); cilium organization (ortholog); PARTICIPATES I N E-cadherin signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Alzheimer's disease (ortholog); atherosclerosis (ortholog); FOUND IN apical junction complex (ortholog); cell surface (ortholog); cell-cell contact zone (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17beta-estradiol | 1 | 88500086 | 88535474 | Rat | 222 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307750 | Nedd1 | NEDD1 gamma-tubulin ring complex targeting factor | INVOLVED IN cell division (inferred); FOUND IN apical part of cell (ortholog); centriole (ortholog); centrosome (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; aflatoxin B1 | 7 | 29120200 | 29161634 | Rat | 89 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307419 | Nek3 | NIMA-related kinase 3 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN establishment of cell polarity (ortholog); neuron projection morphogenesis (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer sy ndrome (ortholog); FOUND IN axon (inferred); cytoplasm (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; diazinon | 16 | 76569465 | 76594921 | Rat | 74 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307187 | Nek9 | NIMA-related kinase 9 | ENCODES a protein that exhibits protein kinase activator activity (ortholog); protein kinase binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN mitotic cell cycle (ortholog); regulation of mitotic cell cycle (ortholog); ASSOCIATED WITH ARTHROGRYPOSIS, PERTHES DISEAS E, AND UPWARD GAZE PALSY (ortholog); cleft palate (ortholog); Desbuquois dysplasia (ortholog); FOUND IN centrosome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 6 | 110675107 | 110715586 | Rat | 113 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308316 | Nfam1 | NFAT activating protein with ITAM motif 1 | ENCODES a protein that exhibits transmembrane signaling receptor activity (ortholog); INVOLVED IN B cell differentiation (ortholog); B cell receptor signaling pathway (ortholog); calcineurin-NFAT signaling cascade (ortholog); FOUND IN cell surface (ortholog); membrane (ortholog); membrane raft (orth olog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 116019383 | 116055628 | Rat | 73 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1303310 | Nfkbil1 | NFKB inhibitor like 1 | ENCODES a protein that exhibits transcription regulator inhibitor activity (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); negative regulation of lipopolysaccharide-mediated signaling pathway (orth olog); ASSOCIATED WITH rheumatoid arthritis (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 20 | 3595319 | 3610295 | Rat | 86 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307823 | Nfu1 | NFU1 iron-sulfur cluster scaffold | ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (ortholog); 4 iron, 4 sulfur cluster binding (ortholog); iron ion binding (ortholog); INVOLVED IN iron-sulfur cluster assembly (ortholog); protein maturation (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogene sis pathway; ASSOCIATED WITH genetic disease (ortholog); hereditary spastic paraplegia 93 (ortholog); multiple mitochondrial dysfunctions syndrome (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cocaine | 4 | 121016316 | 121036925 | Rat | 98 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359201 | Nfxl1 | nuclear transcription factor, X-box binding-like 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); cholestasis (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH (+)-schisandrin B; amitrole; bisphenol A | 14 | 35980058 | 36021478 | Rat | 87 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306051 | Nipa2 | NIPA magnesium transporter 2 | ENCODES a protein that exhibits magnesium ion transmembrane transporter activity (inferred); INVOLVED IN magnesium ion transport (ortholog); FOUND IN early endosome (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 1 | 115935759 | 115960034 | Rat | 63 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311459 | Nkd2 | NKD inhibitor of WNT signaling pathway 2 | ENCODES a protein that exhibits ATPase binding (ortholog); growth factor binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN Golgi vesicle fusion to target membrane (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); positive regulation of proteasomal ub iquitin-dependent protein catabolic process (ortholog); PARTICIPATES IN Wnt signaling, canonical pathway; Wnt signaling pathway; FOUND IN basolateral plasma membrane (ortholog); cell periphery (ortholog); cytoplasmic vesicle (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 1 | 31268856 | 31299390 | Rat | 147 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308560 | Nkiras1 | NFKB inhibitor interacting Ras-like 1 | ENCODES a protein that exhibits GTPase activating protein binding (ortholog); INVOLVED IN lung alveolus development (ortholog); Ral protein signal transduction (ortholog); regulation of tumor necrosis factor-mediated signaling pathway (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-t etrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil | 15 | 9924316 | 9934538 | Rat | 69 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309831 | Nlrc4 | NLR family, CARD domain containing 4 | ENCODES a protein that exhibits ATP binding (ortholog); caspase binding (ortholog); endopeptidase activator activity (ortholog); INVOLVED IN activation of innate immune response (ortholog); defense response to bacterium (ortholog); detection of bacterium (ortholog); ASSOCIATED WITH Autoinflammation with Infantile Enterocolitis (ortholog); Chediak-Higashi syndrome (ortholog); Cryopyrin-Associated Periodic Syndromes (ortholog); FOUND IN cytosol (ortholog); IPAF inflammasome complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 6 | 26743658 | 26771783 | Rat | 143 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309166 | Nlrc5 | NLR family, CARD domain containing 5 | ENCODES a protein that exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN innate immune response (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); negative regulation of type I interferon-mediated signaling path way (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); metabolic dysfunction and alcohol associated liver disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 10483601 | 10587223 | Rat | 121 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1309551 | Nol8 | nucleolar protein 8 | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); protein localization to nucleolus (ortholog); rRNA processing (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN nucleolu s (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 17 | 15196881 | 15220265 | Rat | 103 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305727 | Nop16 | NOP16 nucleolar protein | ASSOCIATED WITH Liver Neoplasms (ortholog); pre-malignant neoplasm (ortholog); FOUND IN nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane; bisphenol A | 17 | 10028058 | 10032975 | Rat | 104 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309681 | Npas2 | neuronal PAS domain protein 2 | ENCODES a protein that exhibits DNA binding (ortholog); Hsp90 protein binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN circadian regulation of gene expression (ortholog); circadian rhythm (ortholog); circadian sleep/wake cycle (ortholog); ASSOCIATED WITH auti stic disorder (ortholog); Chronobiology Disorders (ortholog); cocaine abuse (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 9 | 48959225 | 49138036 | Rat | 190 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308136 | Nphp1 | nephrocystin 1 | INVOLVED IN cell projection organization (ortholog); intracellular protein localization (ortholog); photoreceptor cell outer segment organization (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Bardet-Biedl syndrome 1 (ortholog); CAKUT (ortholog); FOUND IN cell-cell junction (ortholog) ; ciliary base (ortholog); ciliary transition zone (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acetamide | 3 | 135413927 | 135469505 | Rat | 140 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309447 | Nptx2 | neuronal pentraxin 2 | ENCODES a protein that exhibits carbohydrate binding (inferred); metal ion binding (inferred); INVOLVED IN neurotransmitter receptor localization to postsynaptic specialization membrane; associative learning (ortholog); ASSOCIATED WITH withdrawal disorder (ortholog); FOUND IN extrinsic component of postsynaptic specialization membrane; glutamatergic synapse; synaptic cleft; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane | 12 | 15151136 | 15162045 | Rat | 126 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1302966 | Nrm | nurim | ENCODES a protein that exhibits actin binding (inferred); phosphatase binding (inferred); ASSOCIATED WITH alcohol dependence (ortholog); FOUND IN nuclear envelope (ortholog); nuclear membrane (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl; 4,4'-sulfonyldi phenol | 20 | 2893126 | 2897725 | Rat | 99 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305156 | Nsmce2 | NSE2 SUMO ligase component of SMC5/6 complex | ENCODES a protein that exhibits SUMO transferase activity (ortholog); INVOLVED IN cellular senescence (ortholog); double-strand break repair via homologous recombination (ortholog); double-strand break repair via nonhomologous end joining (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); Desbuq uois dysplasia (ortholog); Developmental Disabilities (ortholog); FOUND IN chromosome, telomeric region (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH bisphenol A; Cuprizon; finasteride | 7 | 92825568 | 93071037 | Rat | 119 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309289 | Nthl1 | nth-like DNA glycosylase 1 | ENCODES a protein that exhibits class I DNA-(apurinic or apyrimidinic site) endonuclease activity (ortholog); damaged DNA binding (ortholog); DNA N-glycosylase activity (ortholog); INVOLVED IN base-excision repair, AP site formation (ortholog); nucleotide-excision repair (ortholog); PARTICIPATES IN base excision repair pathway; ASSOCIATED WITH Acute Hepatitis; familial adenomatous polyposis (ortholog); familial adenomatous polyposis 1 (ortholog); FOUND IN mitochondrion (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; aflatoxin B1 | 10 | 14160334 | 14166502 | Rat | 162 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306582 | Ntmt1 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 | ENCODES a protein that exhibits histone methyltransferase activity (ortholog); N-terminal protein N-methyltransferase activity (ortholog); protein methyltransferase activity (ortholog); INVOLVED IN chromosome segregation (ortholog); N-terminal peptidyl-alanine trimethylation (ortholog); N-terminal p eptidyl-glycine methylation (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 3 | 34490972 | 34508316 | Rat | 103 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306192 | Ntpcr | nucleoside-triphosphatase, cancer-related | ENCODES a protein that exhibits ribonucleoside triphosphate phosphatase activity (ortholog); PARTICIPATES IN thiamine metabolic pathway; FOUND IN mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 19 | 70598816 | 70612580 | Rat | 83 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310624 | Nudcd1 | NudC domain containing 1 | ASSOCIATED WITH basal cell carcinoma (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; bisphenol A; Cuprizon | 7 | 77436035 | 77480651 | Rat | 82 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359284 | Nudt5 | nudix hydrolase 5 | ENCODES a protein that exhibits 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity (ortholog); 8-oxo-dGDP phosphatase activity (ortholog); ADP-ribose diphosphatase activity (ortholog); INVOLVED IN ATP generation from poly-ADP-D-ribose (ortholog); chromatin remodeling (ortholog); D-rib ose catabolic process (ortholog); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 17 | 77345041 | 77368308 | Rat | 137 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306022 | Nup188 | nucleoporin 188 | ENCODES a protein that exhibits structural constituent of nuclear pore (inferred); INVOLVED IN protein import into nucleus (ortholog); PARTICIPATES IN RNA transport pathway; ASSOCIATED WITH genetic disease (ortholog); microcephaly (ortholog); respiratory failure (ortholog); FOUND IN nuclear envelope (ortholog); INTERACTS WITH 2,4-dinitrotoluene; amphetamine; bisphenol A | 3 | 33957778 | 34014122 | Rat | 76 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310250 | Nup210l | nucleoporin 210-like | INVOLVED IN Sertoli cell development (ortholog); spermatid development (ortholog); PARTICIPATES IN RNA transport pathway; ASSOCIATED WITH Spermatogenic Failure 97 (ortholog); FOUND IN nuclear membrane (inferred); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; amphetamine; bisphenol A | 2 | 177843647 | 177962975 | Rat | 41 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305764 | Nusap1 | nucleolar and spindle associated protein 1 | ENCODES a protein that exhibits microtubule binding (ortholog); INVOLVED IN establishment of mitotic spindle localization (ortholog); mitotic chromosome condensation (ortholog); mitotic cytokinesis (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); micr ocephaly, seizures, and developmental delay (ortholog); FOUND IN mitotic spindle (ortholog); nucleolus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 127057220 | 127092779 | Rat | 253 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310489 | Nxn | nucleoredoxin | ENCODES a protein that exhibits thioredoxin-disulfide reductase (NADPH) activity (ortholog); INVOLVED IN circulatory system development (ortholog); in utero embryonic development (ortholog); negative regulation of protein ubiquitination (ortholog); ASSOCIATED WITH autosomal recessive Robinow syndrom e 2 (ortholog); basal cell carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 10 | 61607557 | 61745807 | Rat | 124 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308296 | Nxnl1 | nucleoredoxin-like 1 | ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN cell redox homeostasis (ortholog); photoreceptor cell maintenance (ortholog); response to oxidative stress (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodi oxine; bisphenol A; manganese(II) chloride | 16 | 18303454 | 18311510 | Rat | 46 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306933 | Odad2 | outer dynein arm docking complex subunit 2 | INVOLVED IN cilium movement (ortholog); determination of left/right symmetry (ortholog); heart development (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Kartagener syndrome (ortholog); male infertility (ortholog); FOUND IN axoneme (ortholog); ciliary base (ortholog); INTERACTS WIT H 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; bisphenol A | 17 | 59910665 | 60104929 | Rat | 69 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310048 | Odad3 | outer dynein arm docking complex subunit 3 | INVOLVED IN cilium movement (ortholog); determination of left/right symmetry (ortholog); outer dynein arm assembly (ortholog); ASSOCIATED WITH genetic disease (ortholog); Kartagener syndrome (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN axoneme (ortholog); centriole (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Cuprizon | 8 | 28796909 | 28810587 | Rat | 68 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311859 | Odad4 | outer dynein arm docking complex subunit 4 | INVOLVED IN brain development (ortholog); cerebrospinal fluid circulation (ortholog); cilium movement (ortholog); ASSOCIATED WITH genetic disease (ortholog); primary ciliary dyskinesia (ortholog); primary ciliary dyskinesia 35 (ortholog); FOUND IN 9+0 motile cilium (ortholog); 9+2 motile cilium (ort holog); axoneme (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 10 | 85980440 | 86008943 | Rat | 99 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307830 | Odr4 | odr-4 GPCR localization factor homolog | FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 13 | 64925573 | 64974395 | Rat | 40 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305007 | Ogfod3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | ENCODES a protein that exhibits dioxygenase activity (inferred); iron ion binding (inferred); L-ascorbic acid binding (inferred); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aconitine | 10 | 106950640 | 106978422 | Rat | 54 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308171 | Ogn | osteoglycin | ENCODES a protein that exhibits growth factor activity (inferred); INVOLVED IN negative regulation of smooth muscle cell proliferation; ASSOCIATED WITH Neoplasm Metastasis (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxin e; 2,3,7,8-Tetrachlorodibenzofuran | 17 | 15238500 | 15259167 | Rat | 126 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304821 | Oma1 | OMA1 zinc metallopeptidase | ENCODES a protein that exhibits metalloendopeptidase activity; INVOLVED IN cellular response to stress (ortholog); cristae formation (ortholog); diet induced thermogenesis (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial intermembrane space (ortholog); mitochondrial membra ne (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 5 | 123312038 | 123455540 | Rat | 149 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302983 | Osmr | oncostatin M receptor | ENCODES a protein that exhibits cytokine binding (ortholog); growth factor binding (ortholog); oncostatin-M receptor activity (ortholog); INVOLVED IN oncostatin-M-mediated signaling pathway (ortholog); positive regulation of cell population proliferation (ortholog); response to cytokine (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN apical plasma membrane (ortholog); external side of plasma membrane (ortholog); oncostatin-M receptor complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 57634517 | 57688802 | Rat | 193 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303110 | Ostn | osteocrin | ENCODES a protein that exhibits hormone activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN bone growth (ortholog); cell surface receptor signaling pathway (ortholog); endochondral bone growth (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH bisphenol A; Muragl itazar; paraquat | 11 | 86947023 | 86983322 | Rat | 49 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305253 | Otor | otoraplin | INVOLVED IN cartilage condensation (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 3 | 150868886 | 150872141 | Rat | 25 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311534 | Oxnad1 | oxidoreductase NAD-binding domain containing 1 | ENCODES a protein that exhibits oxidoreductase activity (inferred); FOUND IN mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 16 | 7299755 | 7328824 | Rat | 58 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310466 | Oxsr1 | oxidative stress responsive kinase 1 | ENCODES a protein that exhibits protein serine/threonine kinase activity; ATP binding (ortholog); identical protein binding (ortholog); INVOLVED IN cell volume homeostasis (ortholog); cellular hyperosmotic response (ortholog); cellular hypotonic response (ortholog); ASSOCIATED WITH hypertension (ort holog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 8 | 127850481 | 127941518 | Rat | 168 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304568 | P3h2 | prolyl 3-hydroxylase 2 | ENCODES a protein that exhibits procollagen-proline 3-dioxygenase activity; INVOLVED IN collagen metabolic process; peptidyl-proline hydroxylation; negative regulation of cell population proliferation (ortholog); ASSOCIATED WITH genetic disease (ortholog); High Myopia with Cataract and Vitreoretinal Degeneration (ortholog); intestinal disease (ortholog); FOUND IN basement membrane (ortholog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 11 | 88139086 | 88280221 | Rat | 130 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311201 | Pabpc6 | poly(A) binding protein, cytoplasmic 6 | ENCODES a protein that exhibits poly(A) binding (ortholog); INVOLVED IN nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (inferred); RNA splicing (inferred); FOUND IN cytoplasmic stress granule (inferred); lamellipodium (inferred); spliceosomal complex (inferred); INTERACTS WITH 1 ,2-dimethylhydrazine; bisphenol A; indole-3-methanol | 1 | 53592902 | 53595978 | Rat | 63 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311045 | Pacrgl | parkin coregulated like | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; tetrachloromethane | 14 | 66744625 | 66769593 | Rat | 27 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305592 | Pagr1 | Paxip1-associated glutamate-rich protein 1 | ENCODES a protein that exhibits nuclear estrogen receptor binding (ortholog); INVOLVED IN chorion development (ortholog); DNA damage response (ortholog); positive regulation of cell cycle G1/S phase transition (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH dilated cardiomy opathy (ortholog); esophagus squamous cell carcinoma (ortholog); lung metastasis (ortholog); FOUND IN histone methyltransferase complex (ortholog); MLL3/4 complex (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 1 | 191053228 | 191055554 | Rat | 93 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305624 | Palmd | palmdelphin | INVOLVED IN regulation of cell shape (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm; dendrite; dendritic spine; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 2 | 207574413 | 207626239 | Rat | 148 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310524 | Parp4 | poly (ADP-ribose) polymerase family, member 4 | ENCODES a protein that exhibits enzyme binding (ortholog); NAD+ poly-ADP-ribosyltransferase activity (ortholog); NAD+-protein mono-ADP-ribosyltransferase activity (ortholog); INVOLVED IN inflammatory response (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; ASSOCIATE D WITH Colonic Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitotic spindle (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 15 | 34806203 | 34908492 | Rat | 87 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307547 | Paxip1 | PAX interacting protein 1 | INVOLVED IN adipose tissue development (ortholog); chorion development (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN histone modification pathway; FOUND IN histone methyltransferase complex (ortholog); MLL3/4 complex (ortholog); nucleus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromod iphenyl ether; bisphenol A; flutamide | 4 | 8258930 | 8310490 | Rat | 91 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306215 | Paxx | PAXX, non-homologous end joining factor | ENCODES a protein that exhibits DNA polymerase binding (ortholog); identical protein binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN DNA damage response (ortholog); double-strand break repair via nonhomologous end joining (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); epilepsy (ortholog); FOUND IN Ku70:Ku80 complex (ortholog); nonhomologous end joining complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 3 | 28672906 | 28676252 | Rat | 75 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305180 | Pbxip1 | PBX homeobox interacting protein 1 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); transcription coactivator activity (ortholog); transcription corepressor activity (ortholog); INVOLVED IN articular cartilage development (ortholog); cell adhesion (ortholog); cell migration (ortholog); ASSOCIATED W ITH Charcot-Marie-Tooth disease type 2 (ortholog); COVID-19 (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | 2 | 177154056 | 177167810 | Rat | 154 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306217 | Pcp2 | Purkinje cell protein 2 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN G protein-coupled opsin signaling pathway (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Brodifacoum | 12 | 6479554 | 6481550 | Rat | 36 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306403 | Pdcd1lg2 | programmed cell death 1 ligand 2 | ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN negative regulation of activated T cell proliferation (ortholog); negative regulation of interleukin-10 production (ortholog); negative regulation of T cell activation (ortholog); ASSOCIATED WITH Spinal Cord Injuries; a utoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A | 1 | 236572497 | 236637490 | Rat | 82 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308028 | Pdgfrl | platelet-derived growth factor receptor-like | ENCODES a protein that exhibits platelet-derived growth factor receptor activity (inferred); INVOLVED IN cellular response to platelet-derived growth factor stimulus (inferred); platelet-derived growth factor receptor signaling pathway (inferred); ASSOCIATED WITH colon carcinoma (ortholog); colorect al cancer (ortholog); Colorectal Neoplasms (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 16 | 58051421 | 58111327 | Rat | 117 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359203 | Pdlim2 | PDZ and LIM domain 2 | ENCODES a protein that exhibits alpha-actinin binding; filamin binding; muscle alpha-actinin binding; INVOLVED IN protein catabolic process (ortholog); FOUND IN cortical actin cytoskeleton; stress fiber; actin cytoskeleton (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrot oluene; 2,4-dinitrotoluene | 15 | 51647195 | 51659904 | Rat | 142 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310838 | Pds5b | PDS5 cohesin associated factor B | ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN negative regulation of cell population proliferation; lens development in camera-type eye (ortholog); mitotic sister chromatid cohesion (ortholog); FOUND IN nucleus; chromatin (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7 ,8-tetrachlorodibenzodioxine; aconitine; bisphenol A | 12 | 5038114 | 5181208 | Rat | 123 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308622 | Pdzd8 | PDZ domain containing 8 | ENCODES a protein that exhibits lipid binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN mitochondrial calcium ion homeostasis (ortholog); mitochondrion-endoplasmic reticulum membrane tethering (ortholog); ASSOCIATED WITH Intellectual Developmental Disorder wi th Autism and Dysmorphic Facies (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); mitochondria-associated endoplasmic reticulum membrane contact site (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 268435304 | 268492923 | Rat | 99 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306055 | Pea15 | proliferation and apoptosis adaptor protein 15 | INVOLVED IN negative regulation of D-glucose import across plasma membrane (ortholog); negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH (+)-pilocarp ine; 1,3-dinitrobenzene; 1-benzylpiperazine | 13 | 87190189 | 87199811 | Rat | 173 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309093 | Peds1 | plasmanylethanolamine desaturase 1 | ENCODES a protein that exhibits plasmanylethanolamine desaturase activity (ortholog); INVOLVED IN ether lipid biosynthetic process (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; amitrol e | 3 | 176769111 | 176788278 | Rat | 49 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307664 | Peg12 | paternally expressed 12 | PARTICIPATES IN Wnt signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acetamide | 1 | 125374399 | 125377002 | Rat | 16 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306320 | Pelp1 | proline, glutamate and leucine rich protein 1 | ENCODES a protein that exhibits chromatin binding (ortholog); SUMO binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); FOUND IN euchromatin (ort holog); MLL1 complex (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 10 | 55593444 | 55610478 | Rat | 97 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304931 | Perm1 | PPARGC1 and ESRR induced regulator, muscle 1 | INVOLVED IN regulation of DNA-templated transcription (ortholog); response to muscle activity (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 5 | 172082249 | 172087542 | Rat | 63 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307070 | Pex11g | peroxisomal biogenesis factor 11 gamma | INVOLVED IN peroxisome fission (ortholog); regulation of peroxisome size (ortholog); PARTICIPATES IN adrenoleukodystrophy pathway; carnitine-acylcarnitine translocase deficiency; fatty acid beta degradation pathway; FOUND IN peroxisomal membrane (ortholog); peroxisome (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 12 | 6301461 | 6329741 | Rat | 69 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310682 | Pex13 | peroxisomal biogenesis factor 13 | ENCODES a protein that exhibits protein transmembrane transporter activity (ortholog); INVOLVED IN cellular response to reactive oxygen species (ortholog); cerebral cortex cell migration (ortholog); fatty acid alpha-oxidation (ortholog); PARTICIPATES IN adrenoleukodystrophy pathway; carnitine-acylca rnitine translocase deficiency; fatty acid beta degradation pathway; ASSOCIATED WITH adrenoleukodystrophy (ortholog); genetic disease (ortholog); infantile Refsum disease (ortholog); FOUND IN peroxisomal membrane; peroxisome; INTERACTS WITH bisphenol A; clofibric acid; cobalt dichloride | 14 | 101804673 | 101822367 | Rat | 128 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308483 | Pex7 | peroxisomal biogenesis factor 7 | ENCODES a protein that exhibits enzyme binding (ortholog); peroxisome matrix targeting signal-2 binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN endochondral ossification (ortholog); ether lipid biosynthetic process (ortholog); fatty acid beta-oxidation (ortholog); ASSOC IATED WITH connective tissue disease (ortholog); Desbuquois dysplasia (ortholog); fundus dystrophy (ortholog); FOUND IN cytosol (ortholog); peroxisomal matrix (ortholog); peroxisome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 1 | 16402319 | 16466304 | Rat | 119 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304926 | Pfas | phosphoribosylformylglycinamidine synthase | ENCODES a protein that exhibits phosphoribosylformylglycinamidine synthase activity (ortholog); INVOLVED IN glutamine metabolic process; response to xenobiotic stimulus; 'de novo' AMP biosynthetic process (ortholog); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine mono phosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; hepatocellular carcinoma; colon adenocarcinoma (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 10 | 54189157 | 54210685 | Rat | 158 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307218 | Pgap4 | post-GPI attachment to proteins GalNAc transferase 4 | ENCODES a protein that exhibits glycosyltransferase activity (ortholog); INVOLVED IN GPI anchor biosynthetic process (ortholog); FOUND IN Golgi membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 5 | 68727422 | 68742571 | Rat | 58 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305221 | Pgm3 | phosphoglucomutase 3 | ENCODES a protein that exhibits phosphoacetylglucosamine mutase activity (ortholog); INVOLVED IN hemopoiesis (ortholog); protein N-linked glycosylation (ortholog); protein O-linked glycosylation (ortholog); PARTICIPATES IN amino sugar metabolic pathway; french type sialuria pathway; glycogen biosynt hetic pathway; ASSOCIATED WITH cervical cancer (ortholog); genetic disease (ortholog); hyper IgE syndrome (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; acrylamide | 8 | 96398331 | 96416045 | Rat | 166 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305052 | Pgs1 | phosphatidylglycerophosphate synthase 1 | ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity (inferred); INVOLVED IN cardiolipin biosynthetic process (inferred); lipid metabolic process (inferred); phosphatidylglycerol biosynthetic process (inferred); PARTICIPATES IN cardiolipin biosynthetic pathway; glycerophospholipid metabolic pathway; ASSOCIATED WITH High Myopia (ortholog); FOUND IN endoplasmic reticulum (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol | 10 | 103713306 | 103748924 | Rat | 88 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305731 | Phf12 | PHD finger protein 12 | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); transcription corepressor activity (ortholog); transcription corepressor binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II ( ortholog); ASSOCIATED WITH Developmental Disease (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); Sin3-type complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 10 | 63368547 | 63417079 | Rat | 84 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359274 | Phospho2 | phosphatase, orphan 2 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); phosphatase activity (inferred); PARTICIPATES IN vitamin B6 metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; bisphenol A | 3 | 74962649 | 74969810 | Rat | 59 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305077 | Pibf1 | progesterone immunomodulatory binding factor 1 | ENCODES a protein that exhibits identical protein binding (ortholog); interleukin-4 receptor binding (ortholog); INVOLVED IN activation of Janus kinase activity (ortholog); cilium assembly (ortholog); mitotic metaphase chromosome alignment (ortholog); ASSOCIATED WITH Dandy-Walker syndrome (ortholog) ; Encephalocele (ortholog); genetic disease (ortholog); FOUND IN centriolar satellite (ortholog); centrosome (ortholog); extracellular space (ortholog); INTERACTS WITH bisphenol A; diuron; glyphosate | 15 | 82258243 | 82427546 | Rat | 87 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306233 | Pierce1 | piercer of microtubule wall 1 | INVOLVED IN axoneme assembly (ortholog); cellular response to UV-C (ortholog); cilium movement (ortholog); FOUND IN axonemal A tubule inner sheath (ortholog); axonemal microtubule (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 3 | 32195024 | 32201111 | Rat | 59 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311438 | Pigh | phosphatidylinositol glycan anchor biosynthesis, class H | INVOLVED IN GPI anchor biosynthetic process (ortholog); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; ASSOCIATED WITH Glycosylphosphatidylinositol Biosynthesis Defect 17 (ortholog); prostate cancer (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); glycosylph osphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 6 | 103601369 | 103630214 | Rat | 70 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306753 | Pigk | phosphatidylinositol glycan anchor biosynthesis, class K | ENCODES a protein that exhibits GPI-anchor transamidase activity (ortholog); INVOLVED IN attachment of GPI anchor to protein (ortholog); GPI anchored protein biosynthesis (ortholog); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorder with Hypotonia and Cerebellar Atrophy, with or without Seizures (ortholog); FOUND IN GPI-anchor transamidase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 2 | 244289928 | 244375394 | Rat | 89 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309498 | Pigo | phosphatidylinositol glycan anchor biosynthesis, class O | ENCODES a protein that exhibits mannose-ethanolamine phosphotransferase activity (ortholog); INVOLVED IN GPI anchor biosynthetic process (ortholog); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; ASSOCIATED WITH genetic disease (ortholog); Hirschsprung's disease (ortholog) ; hyperphosphatasia with impaired intellectual development syndrome (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); INTERACTS WITH acrylamide; amphetamine; bisphenol A | 5 | 62040979 | 62052067 | Rat | 68 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307205 | Pigp | phosphatidylinositol glycan anchor biosynthesis, class P | ENCODES a protein that exhibits phosphatidylinositol N-acetylglucosaminyltransferase activity (ortholog); INVOLVED IN GPI anchor biosynthetic process (ortholog); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; ASSOCIATED WITH developmental and epileptic encephalopathy (orth olog); developmental and epileptic encephalopathy 55 (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil | 11 | 47152601 | 47158766 | Rat | 101 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307289 | Pigx | phosphatidylinositol glycan anchor biosynthesis, class X | INVOLVED IN GPI anchor biosynthetic process; PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; FOUND IN endoplasmic reticulum membrane; glycosylphosphatidylinositol-mannosyltransferase I complex; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofura n; 6-propyl-2-thiouracil | 11 | 82192125 | 82208062 | Rat | 67 | PANTHER | gene, protein-coding, REVIEWED [RefSeq] |
| 1308747 | Pimreg | PICALM interacting mitotic regulator | FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione | 10 | 57168136 | 57173713 | Rat | 118 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308048 | Pithd1 | PITH domain containing 1 | INVOLVED IN penetration of cumulus oophorus (ortholog); penetration of zona pellucida (ortholog); positive regulation of DNA-templated transcription (ortholog); FOUND IN cytoplasm (ortholog); sperm cytoplasmic droplet (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 5 | 153489529 | 153500025 | Rat | 76 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308476 | Pkhd1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin | INVOLVED IN branching morphogenesis of an epithelial tube (ortholog); cell-cell junction organization (ortholog); cilium assembly (ortholog); ASSOCIATED WITH autosomal recessive polycystic kidney disease; autosomal dominant polycystic kidney disease (ortholog); Caroli disease (ortholog); FOUND IN 9+ 0 non-motile cilium (ortholog); apical plasma membrane (ortholog); centrosome (ortholog); INTERACTS WITH bisphenol A; cefaloridine; rotenone | 9 | 30040466 | 30533834 | Rat | 167 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1309133 | Pkp3 | plakophilin 3 | ENCODES a protein that exhibits alpha-catenin binding (ortholog); cell adhesion molecule binding (ortholog); enzyme binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); desmosome assembly (ortholog); desmosome organization (ortholog); ASSOCIATED WITH lymphopenia (ortholog); ne utropenia (ortholog); Prostatic Neoplasms (ortholog); FOUND IN adherens junction (ortholog); cell junction (ortholog); cell-cell junction (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 205617511 | 205628441 | Rat | 147 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306662 | Plac9 | placenta associated 9 | INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 1466231 | 1481060 | Rat | 57 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308734 | Plbd1 | phospholipase B domain containing 1 | ENCODES a protein that exhibits aminopeptidase activity (ortholog); glycerophospholipase activity (ortholog); INVOLVED IN lysosomal protein catabolic process (ortholog); ASSOCIATED WITH COVID-19 (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN extracellular space (ortholog); lysosome ( ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 171204198 | 171260488 | Rat | 119 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311987 | Pld6 | phospholipase D family, member 6 | ENCODES a protein that exhibits cardiolipin hydrolase activity (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN meiotic cell cycle (ortholog); mitochondrial fusion (ortholog); P granule organization (ortholog); PARTICIPATES IN mitochondria f usion pathway; ASSOCIATED WITH male infertility (ortholog); FOUND IN mitochondrial outer membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 10 | 45078081 | 45080732 | Rat | 89 | PANTHER | gene, protein-coding, INFERRED [RefSeq] |
| 1308269 | Plek | pleckstrin | ENCODES a protein that exhibits phosphatase activator activity (ortholog); phosphatidylinositol-3,4-bisphosphate binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cell projection organization (ortholog); cortical actin cytoskele ton organization (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); osteoporosis (ortholog); rheumatoid arthritis (ortholog); FOUND IN cytoplasm (ortholog); ruffle membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 14 | 95598650 | 95631326 | Rat | 164 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1312029 | Plekhf2 | pleckstrin homology and FYVE domain containing 2 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN protein transport (inferred); FOUND IN transport vesicle (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 5 | 28888358 | 28905350 | Rat | 74 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307005 | Plekhm2 | pleckstrin homology and RUN domain containing M2 | ENCODES a protein that exhibits kinesin binding (ortholog); INVOLVED IN Golgi organization (ortholog); lysosome localization (ortholog); natural killer cell mediated cytotoxicity (ortholog); ASSOCIATED WITH dilated cardiomyopathy (ortholog); FOUND IN endosome membrane (ortholog); lysosomal membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; gentamycin | 5 | 159222620 | 159261666 | Rat | 81 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311019 | Plekhn1 | pleckstrin homology domain containing N1 | ENCODES a protein that exhibits cardiolipin binding (ortholog); phosphatidic acid binding (ortholog); phosphatidylinositol phosphate binding (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); positive regulation of apoptotic process (ortholog); response to hypoxia (ortholog); A SSOCIATED WITH COVID-19 (ortholog); FOUND IN cytoskeleton (ortholog); mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; acetamide | 5 | 172087524 | 172095566 | Rat | 83 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311487 | Plekho1 | pleckstrin homology domain containing O1 | INVOLVED IN lamellipodium morphogenesis (ortholog); myoblast fusion (ortholog); myoblast migration (ortholog); ASSOCIATED WITH bipolar disorder (ortholog); FOUND IN mitochondrion (ortholog); muscle cell projection membrane (ortholog); ruffle membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3, 7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 2 | 186233435 | 186242114 | Rat | 114 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307513 | Pmel | premelanosome protein | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN melanin biosynthetic process (ortholog); melanosome organization (ortholog); positive regulation of melanin biosynthetic process (ortholog); ASSOCIATED WITH coat/hair pigmentation trait (ortholog); melanoma (ortholog); FOUND IN cis-Golgi network membrane (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; atrazine | 7 | 1721948 | 1733248 | Rat | 96 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310897 | Pmm1 | phosphomannomutase 1 | ENCODES a protein that exhibits phosphomannomutase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); mannose metabolic process (ortholog); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; ASSOCIATED WITH GLOBAL DEVELOPMENTAL DELAY, ABSENT OR HYPOPLASTIC CORPUS CALLOSUM, AND DYSMORPHIC FACIES (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); neuronal cell body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 7 | 115346767 | 115357137 | Rat | 125 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310812 | Pmvk | phosphomevalonate kinase | ENCODES a protein that exhibits phosphomevalonate kinase activity; ATP binding (ortholog); INVOLVED IN isopentenyl diphosphate biosynthetic process, mevalonate pathway; cholesterol biosynthetic process (ortholog); cholesterol biosynthetic process via desmosterol (ortholog); PARTICIPATES IN alendrona te pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH genetic disease (ortholog); porokeratosis (ortholog); Porokeratosis 1, Multiple Types (ortholog); FOUND IN cytosol (ortholog); peroxisome (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 177174344 | 177184076 | Rat | 218 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311444 | Pnpla8 | patatin like domain 8, phospholipase A2 | ENCODES a protein that exhibits A2-type glycerophospholipase activity (ortholog); calcium-independent phospholipase A2 activity (ortholog); INVOLVED IN arachidonate metabolic process (ortholog); arachidonate secretion (ortholog); cardiolipin metabolic process (ortholog); ASSOCIATED WITH genetic dise ase (ortholog); Mitochondrial Myopathy with Lactic Acidosis (ortholog); FOUND IN membrane (ortholog); mitochondrion (ortholog); peroxisomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 6 | 67056783 | 67118714 | Rat | 160 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310597 | Poc5 | POC5 centriolar protein | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN centriole elongation (ortholog); negative regulation of centriole elongation (ortholog); ASSOCIATED WITH fundus dystrophy (ortholog); optic atrophy (ortholog); retinitis pigmentosa (ortholog); FOUND IN centriole (ortho log); centrosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 2 | 29454392 | 29483468 | Rat | 61 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305815 | Podxl2 | podocalyxin-like 2 | INVOLVED IN leukocyte tethering or rolling (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 4 | 122863476 | 122895318 | Rat | 65 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309893 | Polh | DNA polymerase eta | ENCODES a protein that exhibits DNA-directed DNA polymerase activity (ortholog); INVOLVED IN cellular response to UV-C (ortholog); DNA damage tolerance (ortholog); DNA synthesis involved in DNA repair (ortholog); ASSOCIATED WITH breast cancer (ortholog); female breast cancer (ortholog); genetic dise ase (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 9 | 22275929 | 22310576 | Rat | 148 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305212 | Poli | DNA polymerase iota | ENCODES a protein that exhibits DNA-directed DNA polymerase activity (ortholog); INVOLVED IN cellular response to UV-C (ortholog); translesion synthesis (ortholog); FOUND IN nuclear speck (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 18 | 66389214 | 66409734 | Rat | 93 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309395 | Polr2i | RNA polymerase II subunit I | ENCODES a protein that exhibits DNA-directed RNA polymerase activity (inferred); metal ion binding (inferred); nucleic acid binding (inferred); INVOLVED IN transcription by RNA polymerase II (ortholog); transcription elongation by RNA polymerase II (ortholog); transcription initiation at RNA polymer ase II promoter (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; Huntington's disease pathway; purine metabolic pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog); RNA polymerase II, core complex (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 1 | 94610976 | 94612413 | Rat | 105 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305574 | Polr3a | RNA polymerase III subunit A | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-directed RNA polymerase activity (ortholog); DNA/RNA hybrid binding (ortholog); INVOLVED IN innate immune response (ortholog); positive regulation of interferon-beta production (ortholog); termination of RNA polymerase III transcripti on (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; purine metabolic pathway; pyrimidine metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); genetic disease (ortholog); hypomyelinating leukodystrophy 4 (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 56066 | 95060 | Rat | 86 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305889 | Polr3h | RNA polymerase III subunit H | ENCODES a protein that exhibits DNA-directed RNA polymerase activity (ortholog); INVOLVED IN nucleobase-containing compound metabolic process (ortholog); termination of RNA polymerase III transcription (ortholog); transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase III tra nscription pathway; purine metabolic pathway; pyrimidine metabolic pathway; ASSOCIATED WITH primary ovarian insufficiency (ortholog); FOUND IN centrosome (ortholog); nucleoplasm (ortholog); RNA polymerase III complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol | 7 | 115309571 | 115319881 | Rat | 99 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311819 | Pop5 | POP5 ribonuclease P/MRP subunit | ENCODES a protein that exhibits ribonuclease P activity (ortholog); ribonuclease P RNA binding (ortholog); INVOLVED IN tRNA 5'-leader removal (ortholog); tRNA processing (ortholog); PARTICIPATES IN tRNA maturation pathway; ribosome biogenesis pathway; RNA transport pathway; FOUND IN multimeric ribon uclease P complex (ortholog); nucleolar ribonuclease P complex (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol | 12 | 47037451 | 47045778 | Rat | 116 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306413 | Pop7 | POP7 ribonuclease P/MRP subunit | ENCODES a protein that exhibits ribonuclease P activity (ortholog); ribonuclease P RNA binding (ortholog); INVOLVED IN tRNA 5'-leader removal (ortholog); PARTICIPATES IN tRNA maturation pathway; ribosome biogenesis pathway; RNA transport pathway; FOUND IN multimeric ribonuclease P complex (ortholog) ; nucleolus (ortholog); ribonuclease MRP complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 12 | 24826161 | 24827202 | Rat | 79 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311411 | Ppie | peptidylprolyl isomerase E | ENCODES a protein that exhibits mRNA binding (ortholog); peptidyl-prolyl cis-trans isomerase activity (ortholog); poly(A) binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); positive regulation of viral genome replication (ortholog); regulation of DNA-templated transcription ( ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,4-dibromophenyl 2,4,5-tribromophenyl ether | 5 | 140691285 | 140704347 | Rat | 92 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309484 | Ppil2 | peptidylprolyl isomerase like 2 | ENCODES a protein that exhibits peptidyl-prolyl cis-trans isomerase activity (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-ubiquitin ligase activity (ortholog); INVOLVED IN protein localization to plasma membrane (ortholog); protein polyubiquitination (ortholog); PARTICIPATES I N spliceosome pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 11 | 97401944 | 97424581 | Rat | 88 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311051 | Ppil4 | peptidylprolyl isomerase like 4 | ENCODES a protein that exhibits isomerase activity (inferred); nucleic acid binding (inferred); peptidyl-prolyl cis-trans isomerase activity (inferred); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; bisphenol A | 1 | 4093956 | 4126016 | Rat | 83 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310383 | Pptc7 | protein phosphatase targeting COQ7 | ENCODES a protein that exhibits protein serine/threonine phosphatase activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN negative regulation of mitophagy (ortholog); positive regulation of ubiquinone biosynthetic process (ortholog); ASSOCIATED WITH Chemical and Drug I nduced Liver Injury (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrial outer membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine | 12 | 39910728 | 39949101 | Rat | 109 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311754 | Prc1 | protein regulator of cytokinesis 1 | ENCODES a protein that exhibits identical protein binding (ortholog); kinesin binding (ortholog); protein kinase binding (ortholog); INVOLVED IN positive regulation of cell population proliferation (ortholog); regulation of cytokinesis (ortholog); ASSOCIATED WITH Breast Cancer, Familial (ortholog); Breast Neoplasms (ortholog); hepatocellular carcinoma (ortholog); FOUND IN contractile ring (ortholog); microtubule cytoskeleton (ortholog); midbody (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 1 | 143659312 | 143681019 | Rat | 251 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307865 | Prex2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | ENCODES a protein that exhibits GTPase activator activity (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN adult locomotory behavior (ortholog); dendrite morphogenesis (ortholog); G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH arteriovenous mal formations of the brain (ortholog); cholangiocarcinoma (ortholog); head and neck squamous cell carcinoma (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 5 | 12720683 | 13036077 | Rat | 106 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308976 | Prg4 | proteoglycan 4 | ENCODES a protein that exhibits polysaccharide binding (inferred); scavenger receptor activity (inferred); INVOLVED IN hematopoietic stem cell proliferation (ortholog); negative regulation of interleukin-6 production (ortholog); regulation of cell population proliferation (ortholog); ASSOCIATED WITH arthrogryposis multiplex congenita (ortholog); camptodactyly-arthropathy-coxa vara-pericarditis syndrome (ortholog); Contracture (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide | 13 | 65037363 | 65054764 | Rat | 118 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309628 | Prkcsh | PRKCSH beta subunit of glucosidase II | ENCODES a protein that exhibits protein-containing complex binding; calcium ion binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN in utero embryonic development (ortholog); liver development (ortholog); N-glycan processing (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH genetic disease (ortholog); hepatitis B (ortholog); liver disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); glucosidase II complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione; bisphenol A | 8 | 28810836 | 28822503 | Rat | 127 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305089 | Prorp | protein only RNase P catalytic subunit | ENCODES a protein that exhibits ribonuclease P activity (ortholog); INVOLVED IN mitochondrial tRNA 5'-end processing (ortholog); ASSOCIATED WITH combined oxidative phosphorylation deficiency 54 (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrial nucleoid (ortholog); mitochondrial rib onuclease P complex (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; acrylamide; bisphenol A | 6 | 78404821 | 78497562 | Rat | 75 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307103 | Prpf6 | pre-mRNA processing factor 6 | ENCODES a protein that exhibits identical protein binding (ortholog); protein-macromolecule adaptor activity (ortholog); ribonucleoprotein complex binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); RNA loca lization (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH fundus dystrophy (ortholog); neuronal ceroid lipofuscinosis (ortholog); retinitis pigmentosa (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; Aroclor 1254; bisphenol A | 3 | 189084465 | 189148705 | Rat | 130 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309896 | Prr12 | proline rich 12 | INVOLVED IN intracellular protein localization (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); intellectual disability (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amphetamine | 1 | 104646492 | 104670454 | Rat | 68 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307129 | Prr13 | proline rich 13 | INVOLVED IN DNA-templated transcription (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 7 | 135471040 | 135474344 | Rat | 89 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310384 | Prr27 | proline rich 27 | INTERACTS WITH bisphenol A; fenvalerate; (+)-catechin (ortholog) | 14 | 20511998 | 20527861 | Rat | 8 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307288 | Prr29 | proline rich 29 | INTERACTS WITH alpha-Zearalanol; bisphenol A; perfluorooctanoic acid | 10 | 91804291 | 91810213 | Rat | 22 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303270 | Prr3 | proline rich 3 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide | 20 | 2797677 | 2804674 | Rat | 69 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305752 | Psmd2 | proteasome 26S subunit ubiquitin receptor, non-ATPase 2 | ENCODES a protein that exhibits enzyme regulator activity (inferred); INVOLVED IN regulation of AMPA receptor activity; PARTICIPATES IN ubiquitin/proteasome degradation pathway; FOUND IN synaptic vesicle; proteasome accessory complex (ortholog); proteasome complex (ortholog); INTERACTS WITH 1,1,1-Tr ichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,6-dinitrotoluene | 11 | 93752761 | 93763388 | Rat | 139 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305454 | Psmg1 | proteasome assembly chaperone 1 | ENCODES a protein that exhibits molecular adaptor activity (ortholog); proteasome binding (ortholog); INVOLVED IN cerebellar granule cell precursor proliferation (ortholog); chaperone-mediated protein complex assembly (ortholog); proteasome core complex assembly (ortholog); ASSOCIATED WITH ulcerativ e colitis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 11 | 48745581 | 48755040 | Rat | 95 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307992 | Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 | ENCODES a protein that exhibits protein tyrosine kinase binding; kinase binding (ortholog); phosphatase activity (ortholog); INVOLVED IN regulation of calcium ion transmembrane transport; regulation of peptidyl-tyrosine phosphorylation; cellular response to muramyl dipeptide (ortholog); ASSOCIATED W ITH hyperglycemia; increased urine glucose level; ASSOCIATED WITH Experimental Arthritis; type 1 diabetes mellitus; Addison's disease (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 194055165 | 194103209 | Rat | 234 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310165 | Ptrh1 | peptidyl-tRNA hydrolase 1 homolog | ENCODES a protein that exhibits peptidyl-tRNA hydrolase activity (ortholog); INVOLVED IN rescue of stalled cytosolic ribosome (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-t etrachlorodibenzodioxine | 3 | 36462575 | 36475605 | Rat | 80 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307190 | Pum1 | pumilio RNA-binding family member 1 | ENCODES a protein that exhibits miRNA binding (ortholog); mRNA 3'-UTR binding (ortholog); RNA binding (ortholog); INVOLVED IN adult locomotory behavior (ortholog); miRNA processing (ortholog); mRNA destabilization (ortholog); ASSOCIATED WITH cerebellar ataxia type 47 (ortholog); Chemical and Drug In duced Liver Injury (ortholog); Developmental Disabilities (ortholog); FOUND IN axon; cytoplasm (ortholog); cytoplasmic stress granule (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil | 5 | 148120712 | 148238468 | Rat | 140 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310054 | Qtrt2 | queuine tRNA-ribosyltransferase accessory subunit 2 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN tRNA wobble guanine modification (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of mitochondrial outer membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; amitrole; amphetamine | 11 | 70312352 | 70343139 | Rat | 81 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310612 | Rabepk | Rab9 effector protein with kelch motifs | ASSOCIATED WITH High Myopia (ortholog); FOUND IN cytoplasm (inferred); endosome membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol | 3 | 38460205 | 38481077 | Rat | 60 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304620 | Rabgap1l | RAB GTPase activating protein 1-like | ENCODES a protein that exhibits GTPase activator activity (ortholog); small GTPase binding (ortholog); INVOLVED IN regulation of cilium assembly (ortholog); regulation of protein localization (ortholog); ASSOCIATED WITH cholesteatoma (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cili um (ortholog); early endosome (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 13 | 74997542 | 75593240 | Rat | 160 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307615 | Rabl6 | RAB, member RAS oncogene family-like 6 | ENCODES a protein that exhibits GTP binding (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); intellectual disability (ortholog); Meniere's disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; aconitine | 3 | 28800802 | 28826722 | Rat | 90 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306944 | Rad51d | RAD51 paralog D | ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); ATP-dependent DNA damage sensor activity (ortholog); four-way junction DNA binding (ortholog); INVOLVED IN chromosome organization (ortholog); DNA damage response (ortholog); DNA strand invasion (ortholog); PARTICIPATE S IN homologous recombination pathway of double-strand break repair; ASSOCIATED WITH breast cancer (ortholog); Chromosome Deletion (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN centrosome (ortholog); chromosome, telomeric region (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 68303350 | 68322002 | Rat | 143 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304975 | Rad52 | RAD52 DNA repair protein | ENCODES a protein that exhibits DNA binding (ortholog); identical protein binding (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); DNA double-strand break processing involved in repair via single-strand annealing (ortholog); DNA recomb ination (ortholog); PARTICIPATES IN homologous recombination pathway of double-strand break repair; ASSOCIATED WITH colon cancer (ortholog); colorectal cancer (ortholog); hepatocellular carcinoma (ortholog); FOUND IN nucleus (ortholog); protein-containing complex (ortholog); protein-DNA complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 4 | 154778320 | 154802002 | Rat | 140 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306861 | Ralgapb | Ral GTPase activating protein non-catalytic subunit beta | ENCODES a protein that exhibits GTPase activator activity; protein heterodimerization activity; INVOLVED IN activation of GTPase activity; Ral protein signal transduction (ortholog); regulation of exocyst localization (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); High Myopia (ortholo g); intellectual disability (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; oxaliplatin | 3 | 167482344 | 167571975 | Rat | 71 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310022 | Ramac | RNA guanine-7 methyltransferase activating subunit | ENCODES a protein that exhibits enzyme activator activity (ortholog); molecular function activator activity (ortholog); RNA binding (ortholog); INVOLVED IN 7-methylguanosine mRNA capping (ortholog); PARTICIPATES IN 5'-end pre-mRNA capping pathway; FOUND IN mRNA cap methyltransferase RNMT:RAMAC compl ex (ortholog); mRNA capping enzyme complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; azoxystrobin | 1 | 145117752 | 145123640 | Rat | 75 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311592 | Rapsn | receptor-associated protein of the synapse | ENCODES a protein that exhibits ionotropic glutamate receptor binding; acetylcholine receptor binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN establishment of protein localization to postsynaptic membrane; positive regulation of neuromuscular synaptic transmission; regulation of postsynaptic membrane organization; PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH Experimental Autoimmune Myasthenia Gravis; autoimmune disease (ortholog); congenital myasthenic syndrome (ortholog); FOUND IN neuromuscular junction; Golgi apparatus (ortholog); membrane (ortholog); INTERACTS WITH atrazine; bisphenol A; cadmium dichloride | 3 | 97470891 | 97480196 | Rat | 104 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310873 | Rasl10b | RAS-like, family 10, member B | ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); nucleotide binding (inferred); INVOLVED IN positive regulation of peptide hormone secretion (ortholog); regulation of systemic arterial blood pressure by atrial natriuretic peptide (ortholog); ASSOCIATED WITH polycys tic ovary syndrome (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 68707315 | 68719642 | Rat | 72 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359190 | Raver1 | ribonucleoprotein, PTB-binding 1 | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 8 | 27886641 | 27907192 | Rat | 62 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307610 | Raver2 | ribonucleoprotein, PTB-binding 2 | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); FOUND IN nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; amitrole | 5 | 120796807 | 120898281 | Rat | 70 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309346 | Rb1cc1 | RB1-inducible coiled-coil 1 | ENCODES a protein that exhibits protein kinase binding (ortholog); protein-membrane adaptor activity (ortholog); INVOLVED IN autophagosome assembly (ortholog); autophagy (ortholog); defense response to virus (ortholog); PARTICIPATES IN autophagy pathway; mTOR signaling pathway; ASSOCIATED WITH breas t adenocarcinoma (ortholog); breast cancer (ortholog); Breast Cancer, Familial (ortholog); FOUND IN Atg1/ULK1 kinase complex (ortholog); autophagosome membrane (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 5 | 17948522 | 18012434 | Rat | 183 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305532 | Rbbp5 | RB binding protein 5, histone lysine methyltransferase complex subunit | ENCODES a protein that exhibits histone binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN DNA damage response (ortholog); gene expression (ortholog); response to estrogen (ortholog); PARTICIPATES IN histone modification pathway; FOUND IN histone methyltransferas e complex (ortholog); MLL1 complex (ortholog); MLL3/4 complex (ortholog); INTERACTS WITH (+)-schisandrin B; bisphenol A; flutamide | 13 | 46464389 | 46494244 | Rat | 92 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311966 | Rbm27 | RNA binding motif protein 27 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); FOUND IN cytoplasm (inferred); nuclear speck (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 18 | 34524523 | 34587115 | Rat | 47 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307558 | Rcc1l | RCC1 like | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); rRNA binding (ortholog); INVOLVED IN mitochondrial fusion (ortholog); mitochondrial large ribosomal subunit assembly (ortholog); mitochondrial small ribosomal subunit assembly (ortholog); ASSOCIATED WITH Williams- Beuren syndrome (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial matrix (ortholog); mitochondrial membrane (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol; 4-amino-2,6-dinitrotoluene | 12 | 28179205 | 28210462 | Rat | 79 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309986 | Rcc2 | regulator of chromosome condensation 2 | ENCODES a protein that exhibits microtubule binding (ortholog); protein domain specific binding (ortholog); protein kinase binding (ortholog); INVOLVED IN activation of GTPase activity (ortholog); chromosome passenger complex localization to kinetochore (ortholog); establishment of protein localizat ion (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN chromosome, centromeric core domain (ortholog); early endosome membrane (ortholog); membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,4-dinitrotoluene | 5 | 158277476 | 158300294 | Rat | 187 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309901 | Rccd1 | RCC1 domain containing 1 | ASSOCIATED WITH Breast Neoplasms (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; aflatoxin B1 | 1 | 143681124 | 143690817 | Rat | 58 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305320 | Rcl1 | RNA terminal phosphate cyclase-like 1 | ENCODES a protein that exhibits catalytic activity (inferred); INVOLVED IN endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (ortholog); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcrip t (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (ortholog); ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); psychotic disorder (ortholog); FOUND IN nucleolus (ortholog); small-subunit processome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; acetamide | 1 | 236238078 | 236282597 | Rat | 125 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310432 | Rdm1 | RAD52 motif containing 1 | ENCODES a protein that exhibits DNA binding (inferred); RNA binding (inferred); INVOLVED IN DNA recombination (inferred); double-strand break repair (inferred); FOUND IN cytosol (ortholog); nucleolus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4, 4'-sulfonyldiphenol | 10 | 87062322 | 87073273 | Rat | 95 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311874 | Rec114 | REC114 meiotic recombination protein | INVOLVED IN meiotic DNA double-strand break formation (ortholog); oogenesis (ortholog); spermatogenesis (ortholog); ASSOCIATED WITH Oocyte/Zygote/Embryo Maturation Arrest 10 (ortholog); FOUND IN chromosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl- 2-thiouracil | 8 | 67959181 | 68117296 | Rat | 42 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307468 | Rell1 | RELT-like 1 | INVOLVED IN positive regulation of p38MAPK cascade (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A | 14 | 44672121 | 44732081 | Rat | 92 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306715 | Rev1 | REV1, DNA directed polymerase | ENCODES a protein that exhibits deoxycytidyl transferase activity (ortholog); DNA binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN DNA biosynthetic process (ortholog); DNA repair (ortholog); error-prone translesion synthesis (ortholog); FOUND IN nuclear replication fork (ortholog); nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 47773907 | 47847554 | Rat | 160 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307087 | Rev3l | REV3 like, DNA directed polymerase zeta catalytic subunit | ENCODES a protein that exhibits DNA-directed DNA polymerase activity (ortholog); INVOLVED IN DNA biosynthetic process (ortholog); DNA repair (ortholog); error-prone translesion synthesis (ortholog); ASSOCIATED WITH colon carcinoma (ortholog); genetic disease (ortholog); FOUND IN nucleolus (ortholog) ; site of DNA damage (ortholog); zeta DNA polymerase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 20 | 44686482 | 44844668 | Rat | 159 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306832 | Rfc3 | replication factor C subunit 3 | ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); DNA binding (ortholog); DNA clamp loader activity (ortholog); INVOLVED IN DNA replication (ortholog); DNA-templated DNA replication (ortholog); positive regulation of DNA-directed DNA polymerase activity (ortholog); PA RTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; DNA replication pathway; FOUND IN Ctf18 RFC-like complex (ortholog); DNA replication factor C complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 12 | 5836546 | 5847331 | Rat | 179 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307304 | Rftn2 | raftlin family member 2 | INVOLVED IN dsRNA transport (ortholog); response to exogenous dsRNA (ortholog); FOUND IN plasma membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil | 9 | 64146062 | 64202342 | Rat | 73 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307023 | Rhot1 | ras homolog family member T1 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); calcium ion binding (ortholog); GDP binding (ortholog); INVOLVED IN establishment of mitochondrion localization by microtubule attachment; regulation of neurotransmitter secretion; regulation of organelle transport along microtubule ; PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH motor neuron disease (ortholog); FOUND IN mitochondrial outer membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH bisphenol A; copper atom; copper(0) | 10 | 65685687 | 65760682 | Rat | 100 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306880 | Rimkla | ribosomal modification protein rimK-like family member A | ENCODES a protein that exhibits N-acetyl-L-aspartate-L-glutamate ligase activity (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; paracetamol | 5 | 138357463 | 138384132 | Rat | 64 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1305938 | Rimoc1 | RAB7A interacting MON1-CCZ1 complex subunit 1 | INVOLVED IN mitophagy (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; acetamide | 2 | 54917383 | 54931577 | Rat | 35 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311588 | Riok2 | RIO kinase 2 | ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); kinase activity (inferred); INVOLVED IN maturation of SSU-rRNA (ortholog); positive regulation of ribosomal small subunit export from nucleus (ortholog); positive regulation of rRNA processing (ortholog); PARTICIP ATES IN ribosome biogenesis pathway; FOUND IN cytoplasm (ortholog); preribosome, small subunit precursor (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; bisphenol A | 1 | 66776215 | 66792480 | Rat | 102 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307772 | Ripor1 | RHO family interacting cell polarization regulator 1 | ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); INVOLVED IN cellular response to chemokine (ortholog); cellular response to starvation (ortholog); establishment of Golgi localization (ortholog); FOUND IN cell leading edge (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTER ACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 19 | 50387447 | 50416323 | Rat | 97 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306772 | Rita1 | RBPJ interacting and tubulin associated 1 | ENCODES a protein that exhibits tubulin binding (ortholog); INVOLVED IN negative regulation of Notch signaling pathway (ortholog); neurogenesis (ortholog); nuclear export (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodi oxine; 6-propyl-2-thiouracil; atrazine | 12 | 41610713 | 41614545 | Rat | 56 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309546 | Rmnd1 | required for meiotic nuclear division 1 homolog | INVOLVED IN positive regulation of mitochondrial translation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); combined oxidative phosphorylation deficiency 11 (ortholog); genetic disease (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A | 1 | 43265207 | 43299748 | Rat | 74 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311458 | Rmp64 | ribonuclease MRP subunit p64 | INVOLVED IN negative regulation of neuron differentiation (ortholog); positive regulation of Notch signaling pathway (ortholog); RNA processing (ortholog); ASSOCIATED WITH anauxetic dysplasia 3 (ortholog); microcephaly (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortho log); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 11 | 69464263 | 69476429 | Rat | 48 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306139 | Rnf11l2 | ring finger protein 11-like 2 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN ubiquitin-dependent protein catabolic process (inferred); FOUND IN cytoplasm (inferred); early endosome (inferred); nucleus (inferred); INTERACTS WITH 2-methoxyethanol; finasteride; glafenine | 9 | 89629692 | 89631995 | Rat | 14 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307857 | Rnf121 | ring finger protein 121 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A | 1 | 165789356 | 165858832 | Rat | 50 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305251 | Rnf152 | ring finger protein 152 | ENCODES a protein that exhibits small GTPase binding (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of TORC1 signaling (ortholog); positive regulation of autophagy (ortholog); FOUND IN lysosomal membrane (ortholog); lysosome (ortholog); organelle membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 13 | 21838634 | 21918000 | Rat | 135 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310486 | Rnf17 | ring finger protein 17 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN spermatid development (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH bisphenol A; N,N-diethyl-m-toluamide; permethrin | 15 | 34603448 | 34741658 | Rat | 30 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310573 | Rnf222 | ring finger protein 222 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A | 10 | 54090219 | 54102161 | Rat | 24 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305953 | Rnf26 | ring finger protein 26 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN endosome organization (ortholog); negative regulation of defense response to virus (ortholog); protein K11-linked ubiquitination (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2, 3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 8 | 53351388 | 53353586 | Rat | 80 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309804 | Rnls | renalase, FAD-dependent amine oxidase | ENCODES a protein that exhibits epinephrine binding (ortholog); monoamine oxidase activity (ortholog); NADH binding (ortholog); INVOLVED IN response to catecholamine; response to epinephrine; response to ischemia; ASSOCIATED WITH chronic kidney disease; congestive heart failure; glomerulosclerosis; FOUND IN extracellular space; extracellular region (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 1 | 240450702 | 240723472 | Rat | 118 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306810 | Rpa3 | replication protein A3 | ENCODES a protein that exhibits damaged DNA binding (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN base-excision repair (ortholog); DNA repair (ortholog); DNA replication (ortholog); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; DNA replication pathway ; FOUND IN DNA replication factor A complex; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 4 | 37270966 | 37273997 | Rat | 163 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308492 | Rpain | RPA interacting protein | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN protein import into nucleus (ortholog); response to UV (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); PML body (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bis phenol F | 10 | 56190975 | 56198490 | Rat | 74 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303036 | Rpap3 | RNA polymerase II associated protein 3 | FOUND IN cytosol (ortholog); R2TP complex (ortholog); INTERACTS WITH bisphenol A; cadmium dichloride; chloroprene | 7 | 130689923 | 130719411 | Rat | 74 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309517 | Rpl22l1 | ribosomal protein L22 like 1 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); FOUND IN cytoplasm (inferred); ribonucleoprotein complex (inferred); ribosome (inferred); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 113683196 | 113685132 | Rat | 122 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305436 | Rpp14 | ribonuclease P/MRP subunit p14 | ENCODES a protein that exhibits ribonuclease P activity (ortholog); ribonuclease P RNA binding (ortholog); INVOLVED IN tRNA 5'-leader removal (ortholog); PARTICIPATES IN tRNA maturation pathway; RNA transport pathway; FOUND IN multimeric ribonuclease P complex (ortholog); nucleolus (ortholog); INTER ACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F | 15 | 19268025 | 19278216 | Rat | 51 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307474 | Rpp38 | ribonuclease P/MRP subunit p38 | ENCODES a protein that exhibits ribonuclease P activity (ortholog); ribonuclease P RNA binding (ortholog); INVOLVED IN tRNA 5'-leader removal (ortholog); PARTICIPATES IN tRNA maturation pathway; ribosome biogenesis pathway; RNA transport pathway; ASSOCIATED WITH melanoma (ortholog); FOUND IN multime ric ribonuclease P complex (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 17 | 79823237 | 79826908 | Rat | 82 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310228 | Rpp40 | ribonuclease P/MRP subunit p40 | ENCODES a protein that exhibits ribonuclease P activity (ortholog); ribonuclease P RNA binding (ortholog); INVOLVED IN tRNA 5'-leader removal (ortholog); PARTICIPATES IN tRNA maturation pathway; ribosome biogenesis pathway; RNA transport pathway; FOUND IN multimeric ribonuclease P complex (ortholog) ; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 17 | 29153203 | 29162241 | Rat | 97 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310904 | Rreb1 | ras responsive element binding protein 1 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-template d transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of brown fat cell differentiation (ortholog); ASSOCIATED WITH amenorrhea (ortholog); Desbuquois dysplasia (ortholog); microcephaly (ortholog); FOUND IN nuclear speck (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A | 17 | 27082217 | 27208061 | Rat | 152 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307286 | Rrp1 | ribosomal RNA processing 1 | INVOLVED IN positive regulation of DNA-templated transcription (inferred); rRNA processing (inferred); ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN chromosome (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; bisphenol A; cadmiu m dichloride | 20 | 10260580 | 10271829 | Rat | 79 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311893 | Rsph10b | radial spoke head 10 homolog B | FOUND IN 9+2 motile cilium (ortholog); cilium (ortholog); sperm flagellum (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; acrylamide | 12 | 15741097 | 15788887 | Rat | 33 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305601 | Rsph14 | radial spoke head 14 homolog | FOUND IN radial spoke (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 20 | 13626707 | 13702817 | Rat | 25 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306786 | Rsph6a | radial spoke head 6 homolog A | INVOLVED IN manchette disassembly (ortholog); sperm flagellum assembly (ortholog); FOUND IN axoneme (ortholog); radial spoke (ortholog); radial spoke head (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; benzo[a]pyrene; bisphenol A | 1 | 87828779 | 87848483 | Rat | 41 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303261 | Rtcb | RNA 2',3'-cyclic phosphate and 5'-OH ligase | ENCODES a protein that exhibits protein guanylyltransferase activity (ortholog); RNA ligase (GTP) activity (ortholog); vinculin binding (ortholog); INVOLVED IN in utero embryonic development (ortholog); IRE1-mediated unfolded protein response (ortholog); mRNA splicing, via endonucleolytic cleavage a nd ligation (ortholog); PARTICIPATES IN tRNA maturation pathway; FOUND IN catalytic complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 7 | 19795393 | 19814875 | Rat | 117 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306706 | Rttn | rotatin | INVOLVED IN determination of left/right symmetry (ortholog); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH bisphenol A; gentamycin; paracetamol | 18 | 84495813 | 84673079 | Rat | 82 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309356 | Rxylt1 | ribitol xylosyltransferase 1 | ENCODES a protein that exhibits ribitol beta-1,4-xylosyltransferase activity (ortholog); INVOLVED IN protein O-linked glycosylation via mannose (ortholog); ASSOCIATED WITH congenital muscular dystrophy-dystroglycanopathy type A10 (ortholog); genetic disease (ortholog); Walker-Warburg syndrome (ortho log); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acetamide | 7 | 59656274 | 59668140 | Rat | 94 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310078 | Sarm1 | sterile alpha and TIR motif containing 1 | ENCODES a protein that exhibits double-stranded DNA binding (ortholog); identical protein binding (ortholog); NAD+ nucleosidase activity (ortholog); INVOLVED IN modification of postsynaptic structure; NAD+ catabolic process (ortholog); nervous system process (ortholog); ASSOCIATED WITH amyotrophic l ateral sclerosis (ortholog); respiratory syncytial virus infectious disease (ortholog); Vision Disorders (ortholog); FOUND IN extrinsic component of synaptic membrane; glutamatergic synapse; cell surface (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 10 | 63867503 | 63890872 | Rat | 142 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305692 | Sarnp | SAP domain containing ribonucleoprotein | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; FOUND IN nuclear speck (ortholog); nucleus (ortholog); transcription export c omplex (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil; benzo[a]pyrene | 7 | 1835597 | 1889833 | Rat | 94 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309378 | Scap | SREBF chaperone | ENCODES a protein that exhibits protein-containing complex binding; sterol binding (ortholog); INVOLVED IN response to vitamin B3; cholesterol metabolic process (ortholog); COPII-coated vesicle cargo loading (ortholog); PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; ASS OCIATED WITH end stage renal disease; Experimental Diabetes Mellitus; Hypercholesterolemia; FOUND IN protein-containing complex; endoplasmic reticulum membrane (ortholog); Golgi membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3,4-methylenedioxymethamphetamine | 8 | 119184366 | 119239086 | Rat | 143 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309269 | Scara3 | scavenger receptor class A, member 3 | FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 15 | 44315422 | 44348416 | Rat | 119 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308968 | Scnm1 | sodium channel modifier 1 | ENCODES a protein that exhibits enzyme binding (ortholog); INVOLVED IN mRNA processing (inferred); pointed-end actin filament capping (inferred); RNA splicing (inferred); FOUND IN cytoskeleton (inferred); nuclear speck (inferred); nucleoplasm (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodiox ine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 2 | 185389892 | 185394126 | Rat | 24 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311860 | Scoc | short coiled-coil protein | INVOLVED IN positive regulation of macroautophagy (ortholog); regulation of protein complex stability (ortholog); FOUND IN endosome (ortholog); Golgi apparatus (ortholog); trans-Golgi network (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 19 | 41564166 | 41593932 | Rat | 97 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305572 | Sde2 | spliceosome associated SDE2 | ENCODES a protein that exhibits damaged DNA binding (ortholog); snoRNA binding (ortholog); INVOLVED IN cellular response to UV (ortholog); endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (ortholog); mitotic G1 DNA damage checkpoint signaling (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 13 | 95110598 | 95126929 | Rat | 104 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309451 | Sec24a | SEC24 homolog A, COPII component | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); COPII-coated vesicle cargo loading (ortholog); endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSO CIATED WITH progressive muscular atrophy (ortholog); FOUND IN COPII vesicle coat (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 36450043 | 36525303 | Rat | 105 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304565 | Senp6 | SUMO specific peptidase 6 | ENCODES a protein that exhibits SUMO-specific endopeptidase activity (ortholog); INVOLVED IN protein desumoylation (ortholog); protein modification by small protein removal (ortholog); regulation of kinetochore assembly (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); postsynaptic cytosol (ortholog); presynaptic cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 8 | 89868115 | 89951803 | Rat | 130 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309955 | Senp8 | SUMO peptidase family member, NEDD8 specific | ENCODES a protein that exhibits cysteine-type peptidase activity (inferred); deNEDDylase activity (inferred); hydrolase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiou racil; alpha-Zearalanol | 8 | 69031230 | 69044616 | Rat | 58 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308827 | Sephs2 | selenophosphate synthetase 2 | ENCODES a protein that exhibits selenide, water dikinase activity (ortholog); INVOLVED IN L-selenocysteine biosynthetic process (ortholog); selenium compound metabolic process (ortholog); PARTICIPATES IN selenoamino acid metabolic pathway; ASSOCIATED WITH colorectal adenoma (ortholog); colorectal ca rcinoma (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 191323637 | 191325955 | Rat | 108 | PANTHER | gene, protein-coding, REVIEWED [RefSeq] |
| 1305576 | Setd2 | SET domain containing 2, histone lysine methyltransferase | ENCODES a protein that exhibits alpha-tubulin binding (ortholog); histone H3K36 methyltransferase activity (ortholog); protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN positive regulation of ossification; response to alkaloid; response to metal ion; PARTICIPATES IN histone modific ation pathway; renal cell carcinoma pathway; lysine degradation pathway; ASSOCIATED WITH Experimental Mammary Neoplasms; adenoid cystic carcinoma (ortholog); Agenesis of Corpus Callosum (ortholog); FOUND IN chromosome (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 8 | 119390207 | 119475863 | Rat | 228 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310433 | Setd5 | SET domain containing 5 | ENCODES a protein that exhibits histone H3 methyltransferase activity (ortholog); histone H3K36 methyltransferase activity (ortholog); histone H3K9 methyltransferase activity (ortholog); INVOLVED IN cognition (ortholog); negative regulation of transcription by RNA polymerase III (ortholog); regulati on of chromatin organization (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal dominant intellectual developmental disorder 23 (ortholog); breast cancer (ortholog); FOUND IN chromatin (ortholog); euchromatin (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; bisphenol A | 4 | 147772955 | 147850669 | Rat | 137 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311477 | Sf3a1 | splicing factor 3A subunit 1 | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN mRNA processing (ortholog); mRNA splicing, via spliceosome (ortholog); U2-type prespliceosome assembly (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH diffuse large B-cell lymphoma (ortholog); FOUND IN catalytic ste p 2 spliceosome (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 14 | 83254971 | 83275720 | Rat | 124 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308726 | Sf3a3 | splicing factor 3a, subunit 3 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN mRNA processing (ortholog); mRNA splicing, via spliceosome (ortholog); U2-type prespliceosome assembly (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH h uman immunodeficiency virus infectious disease (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol; acrylamide | 5 | 142246556 | 142272053 | Rat | 108 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305481 | Sfr1 | SWI5-dependent homologous recombination repair protein 1 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); double-strand break repair via homologous recombination (ortholog); positive regulation of DNA-templated transcription (ortholog); FOUND IN nucleolus (ortholo g); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 1 | 256560533 | 256564547 | Rat | 88 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310623 | Sft2d2 | SFT2 domain containing 2 | INVOLVED IN protein transport (inferred); vesicle-mediated transport (inferred); FOUND IN cytoplasm (inferred); endomembrane system (inferred); membrane (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 13 | 80017854 | 80037144 | Rat | 85 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303180 | Sfta2 | surfactant associated 2 | INTERACTS WITH decabromodiphenyl ether; nitrofen; paraquat | 20 | 3098313 | 3099038 | Rat | 14 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310342 | Shprh | SNF2 histone linker PHD RING helicase | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); protein polyubiquitination (ortholog); FOUND IN nucleosome (inferred); nucleus (in ferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine | 1 | 7349073 | 7422804 | Rat | 94 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311953 | Siglec1 | sialic acid binding Ig like lectin 1 | ENCODES a protein that exhibits virion binding (ortholog); INVOLVED IN clathrin-dependent endocytosis (ortholog); clathrin-dependent endocytosis of virus by host cell (ortholog); negative regulation of phagocytosis (ortholog); ASSOCIATED WITH Human Influenza (ortholog); FOUND IN early endosome (orth olog); endocytic vesicle (ortholog); late endosome (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 138740171 | 138759966 | Rat | 102 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305876 | Sirt7 | sirtuin 7 | ENCODES a protein that exhibits chromatin binding (ortholog); histone H3K18 deacetylase activity, NAD-dependent (ortholog); NAD-dependent protein lysine deacetylase activity (ortholog); INVOLVED IN DNA damage response (ortholog); DNA repair-dependent chromatin remodeling (ortholog); homologous chrom osome pairing at meiosis (ortholog); PARTICIPATES IN histone modification pathway; RNA polymerase I transcription pathway; Sirtuin mediated pathway; ASSOCIATED WITH Reperfusion Injury (ortholog); steatotic liver disease (ortholog); systemic scleroderma (ortholog); FOUND IN chromatin (ortholog); nuclear speck (ortholog); nucleolus (ortholog); INTERACTS WITH (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 10 | 106394802 | 106401627 | Rat | 185 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310784 | Ska1 | spindle and kinetochore associated complex subunit 1 | ENCODES a protein that exhibits microtubule binding (ortholog); INVOLVED IN attachment of mitotic spindle microtubules to kinetochore (ortholog); establishment of meiotic spindle orientation (ortholog); metaphase chromosome alignment (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular ca rcinoma (ortholog); FOUND IN centrosome (ortholog); kinetochore (ortholog); meiotic spindle (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 18 | 70069957 | 70080303 | Rat | 177 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307201 | Ska3 | spindle and kinetochore associated complex subunit 3 | ENCODES a protein that exhibits microtubule binding (ortholog); INVOLVED IN attachment of mitotic spindle microtubules to kinetochore (ortholog); establishment of meiotic spindle orientation (ortholog); metaphase chromosome alignment (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); F OUND IN centrosome (ortholog); kinetochore (ortholog); meiotic spindle (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 36067372 | 36086563 | Rat | 138 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303059 | Skic2 | SKI2 subunit of superkiller complex | ENCODES a protein that exhibits 3'-5' RNA helicase activity (ortholog); INVOLVED IN nuclear-transcribed mRNA catabolic process (ortholog); nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay (ortholog); nuclear-transcribed mRNA catabolic process, non-stop decay ( ortholog); PARTICIPATES IN RNA degradation pathway; ASSOCIATED WITH genetic disease (ortholog); immunodeficiency 57 (ortholog); trichohepatoenteric syndrome (ortholog); FOUND IN Ski complex (ortholog); INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; cadmium dichloride | 20 | 3987130 | 3997887 | Rat | 76 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308228 | Skic8 | SKI8 subunit of superkiller complex | INVOLVED IN negative regulation of myeloid cell differentiation (ortholog); nuclear-transcribed mRNA catabolic process (ortholog); nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymera se II transcription elongation pathway; RNA degradation pathway; FOUND IN Cdc73/Paf1 complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 8 | 63999669 | 64016959 | Rat | 122 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306193 | Slc25a39 | solute carrier family 25, member 39 | ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (ortholog); glutathione transmembrane transporter activity (ortholog); INVOLVED IN cellular response to iron ion (ortholog); glutathione import into mitochondrion (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (o rtholog); FOUND IN mitochondrial inner membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 10 | 87862630 | 87867626 | Rat | 90 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306931 | Slc30a5 | solute carrier family 30 member 5 | ENCODES a protein that exhibits cadmium ion transmembrane transporter activity (ortholog); zinc efflux transmembrane transporter activity (ortholog); zinc ion transmembrane transporter activity (ortholog); INVOLVED IN cobalt ion transport (ortholog); GPI anchor biosynthetic process (ortholog); intra cellular zinc ion homeostasis (ortholog); ASSOCIATED WITH Bradycardia (ortholog); hypertrophic cardiomyopathy (ortholog); FOUND IN apical plasma membrane (ortholog); cytoplasm (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,6-dinitrotoluene; aldehydo-D-glucose; bisphenol A | 2 | 33679800 | 33710025 | Rat | 174 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309250 | Slc30a6 | solute carrier family 30 member 6 | ENCODES a protein that exhibits zinc ion transmembrane transporter activity (ortholog); zinc:proton antiporter activity (ortholog); INVOLVED IN Golgi to endosome transport (ortholog); regulation of zinc ion transport (ortholog); zinc ion import into Golgi lumen (ortholog); ASSOCIATED WITH Alzheimer' s disease (ortholog); FOUND IN Golgi apparatus; apical plasma membrane (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 6 | 26772804 | 26802656 | Rat | 105 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1312016 | Slc43a3 | solute carrier family 43, member 3 | ENCODES a protein that exhibits adenine transmembrane transporter activity (ortholog); fatty acid transmembrane transporter activity (ortholog); guanine transmembrane transporter activity (ortholog); INVOLVED IN hypoxanthine transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); IgA glomerulonep hritis (ortholog); FOUND IN basolateral plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 3 | 90414822 | 90450654 | Rat | 110 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305138 | Slc61a1 | solute carrier family 61 member 1 | ENCODES a protein that exhibits molybdate ion transmembrane transporter activity (ortholog); INVOLVED IN molybdate ion transport (ortholog); response to food (ortholog); response to starvation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodib enzodioxine; 6-propyl-2-thiouracil; acrylamide | 7 | 135287683 | 135289964 | Rat | 59 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304857 | Slf1 | SMC5/6 complex localization factor 1 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN DNA damage response (ortholog); positive regulation of double-strand break repair (ortholog); positive regulation of maintenance of mitotic sister chromatid cohesio n (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); nuclear inclusion body (ortholog); INTERACTS WITH bisphenol A; cadmium dichloride; Cuprizon | 2 | 8498776 | 8606251 | Rat | 83 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306550 | Slitrk6 | SLIT and NTRK-like family, member 6 | INVOLVED IN adult locomotory behavior (ortholog); auditory behavior (ortholog); auditory receptor cell morphogenesis (ortholog); ASSOCIATED WITH breast ductal carcinoma (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN cell periphery (ortholog); cell surface (or tholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; atrazine | 15 | 93977812 | 93984431 | Rat | 112 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304850 | Smarcc1 | SWI/SNF related BAF chromatin remodeling complex subunit C1 | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN prostate gland development; animal organ morphogenesis (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN SWI/SNF family mediated chromatin remodeling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Animal Diseas e Models (ortholog); autism spectrum disorder (ortholog); FOUND IN cytoplasm (ortholog); nBAF complex (ortholog); npBAF complex (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 8 | 118986917 | 119093161 | Rat | 157 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304726 | Smarce1 | SWI/SNF related BAF chromatin remodeling complex subunit E1 | ENCODES a protein that exhibits N-acetyltransferase activity (ortholog); nuclear receptor binding (ortholog); RNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription; spermatid development; chromatin remodeling (ortholog); PARTICIPATES IN SWI/SNF family mediated chroma tin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Coffin-Siris syndrome (ortholog); Coffin-Siris syndrome 5 (ortholog); FOUND IN nBAF complex (ortholog); npBAF complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; benzo[a]pyrene; bisphenol A | 10 | 84655468 | 84678259 | Rat | 153 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307492 | Smc5 | structural maintenance of chromosomes 5 | ENCODES a protein that exhibits DNA secondary structure binding (ortholog); INVOLVED IN cellular senescence (ortholog); chromosome condensation (ortholog); chromosome segregation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); Mosaic Variegated Aneupl oidy Syndrome 6 (ortholog); FOUND IN chromosome, centromeric region (ortholog); chromosome, telomeric region (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 1 | 230195894 | 230265677 | Rat | 125 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311310 | Smdt1 | single-pass membrane protein with aspartate-rich tail 1 | ENCODES a protein that exhibits channel activator activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN calcium import into the mitochondrion (ortholog); cellular response to calcium ion starvation (ortholog); mitochondrial calcium ion homeostasis (ortholog); FOUND IN m itochondrial inner membrane (ortholog); mitochondrion (ortholog); uniplex complex (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; amitrole | 7 | 115742240 | 115745323 | Rat | 51 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1302995 | Smgc | submandibular gland protein C | FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; copper atom; copper(0) | 7 | 124897424 | 124927730 | Rat | 8 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311122 | Smim14 | small integral membrane protein 14 | INVOLVED IN blastocyst hatching (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 14 | 43136754 | 43180622 | Rat | 106 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306625 | Smim23 | small integral membrane protein 23 | INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; acrylamide; bisphenol A | 10 | 17907716 | 17911350 | Rat | 7 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305158 | Smim8 | small integral membrane protein 8 | FOUND IN mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 4,4'-sulfonyldiphenol; bisphenol A | 5 | 54132905 | 54141940 | Rat | 58 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304589 | Snapc2 | small nuclear RNA activating complex, polypeptide 2 | ENCODES a protein that exhibits RNA polymerase II general transcription initiation factor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); snRNA transcription (inferred); transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase III transcription pathway; FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 12 | 7403650 | 7406840 | Rat | 60 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309048 | Snapc4 | small nuclear RNA activating complex, polypeptide 4 | ENCODES a protein that exhibits DNA binding (ortholog); RNA polymerase II general transcription initiation factor activity (ortholog); RNA polymerase III general transcription initiation factor activity (ortholog); INVOLVED IN snRNA transcription by RNA polymerase II (ortholog); snRNA transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); genetic disease (ortholog); long QT syndrome (ortholog); FOUND IN snRNA-activating protein complex (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 4,4'-sulfonyldiphenol | 3 | 29580157 | 29598440 | Rat | 89 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311447 | Snorc | secondary ossification center associated regulator of chondrocyte maturation | INVOLVED IN cartilage development (ortholog); FOUND IN cell periphery (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; gentamycin | 9 | 95574943 | 95593394 | Rat | 36 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305867 | Snph | syntaphilin | INVOLVED IN neuron differentiation; PARTICIPATES IN mitochondria transport pathway; FOUND IN mitochondrial membrane; neuronal cell body; presynaptic membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 3 | 160558929 | 160603636 | Rat | 65 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310925 | Snrnp27 | small nuclear ribonucleoprotein U4/U6.U5 subunit 27 | INVOLVED IN cell differentiation (inferred); germ cell development (inferred); mRNA processing (inferred); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH atrial fibrillation (ortholog); FOUND IN nuclear matrix (inferred); nucleus (inferred); INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; 6-pr opyl-2-thiouracil; amitrole | 4 | 120681054 | 120691343 | Rat | 51 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309198 | Snrnp40 | small nuclear ribonucleoprotein U5 subunit 40 | INVOLVED IN mRNA processing (inferred); RNA splicing (inferred); RNA splicing, via transesterification reactions (inferred); PARTICIPATES IN spliceosome pathway; FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); U2-type catalytic step 2 spliceosome (ortholog); INTERACTS WIT H 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 5 | 147984758 | 148017932 | Rat | 70 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306065 | Snrpc | small nuclear ribonucleoprotein polypeptide C | ENCODES a protein that exhibits U1 snRNP binding; protein homodimerization activity (ortholog); single-stranded RNA binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); spliceosomal snRNP assembly (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH connective tissu e disease (ortholog); mixed connective tissue disease (ortholog); systemic lupus erythematosus (ortholog); FOUND IN U1 snRNP; Cajal body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; bisphenol A | 20 | 5890229 | 5908410 | Rat | 103 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307319 | Snx11 | sorting nexin 11 | ENCODES a protein that exhibits phosphatidylinositol phosphate binding (ortholog); INVOLVED IN vesicle organization (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cytoplasm (ortholog); endosome (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta- estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 10 | 82238475 | 82249264 | Rat | 69 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307787 | Snx20 | sorting nexin 20 | ENCODES a protein that exhibits phosphatidylinositol-3-phosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN protein transport (inferred); FOUND IN early endosome membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; aflatoxin B1 | 19 | 34609397 | 34618569 | Rat | 66 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311367 | Snx30 | sorting nexin family member 30 | ENCODES a protein that exhibits phosphatidylinositol binding (inferred); INVOLVED IN positive regulation of autophagosome assembly (ortholog); protein transport (ortholog); FOUND IN early endosome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; acetamide; amphetamine | 5 | 79478804 | 79608118 | Rat | 68 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309763 | Snx4 | sorting nexin 4 | ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); insulin receptor binding (ortholog); leptin receptor binding (ortholog); INVOLVED IN endocytic recycling (ortholog); positive regulation of autophagosome assembly (ortholog); positive regulation of histamine secreti on by mast cell (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic dynein complex (ortholog); early endosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 4,4'-sulfonyldiphenol | 11 | 80965965 | 81023234 | Rat | 134 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305791 | Snx8 | sorting nexin 8 | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); INVOLVED IN early endosome to Golgi transport (ortholog); intracellular protein transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN early endosome membrane (ortholog); retromer complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amitrole | 12 | 19365746 | 19414333 | Rat | 105 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309013 | Son | SON DNA and RNA binding protein | ENCODES a protein that exhibits RNA binding (ortholog); RS domain binding (ortholog); INVOLVED IN microtubule cytoskeleton organization (ortholog); mitotic cytokinesis (ortholog); mRNA processing (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); congenital anomalies of kidney and urin ary tract syndrome with or without hearing loss, abnormal ears, or developmental delay (ortholog); Developmental Disabilities (ortholog); FOUND IN nuclear speck (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 11 | 44336818 | 44409127 | Rat | 164 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309000 | Sox6 | SRY-box transcription factor 6 | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding; DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN astrocyte differentiation; brain development (ortholog); cardiac muscle cell differentiation (ortholog); ASSOCIATED WITH card iomyopathy (ortholog); Developmental Disease (ortholog); genetic disease (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 179157678 | 179769243 | Rat | 210 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306355 | Sp140 | SP140 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 4,4 '-diaminodiphenylmethane; acetamide | 9 | 93672536 | 93722596 | Rat | 45 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 11442159 | Spacdr | sperm acrosome developmental regulator | INVOLVED IN spermatid development (ortholog); FOUND IN acrosomal vesicle (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Butylbenzyl phthalate; cadmium dichloride | 12 | 24567407 | 24573586 | Rat | 27 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305616 | Spag6 | sperm associated antigen 6 | INVOLVED IN cell projection organization (inferred); FOUND IN axoneme (ortholog); microtubule cytoskeleton (ortholog); sperm end piece (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 17 | 86258418 | 86309922 | Rat | 77 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302954 | Spata21 | spermatogenesis associated 21 | ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); ASSOCIATED WITH Liver Neoplasms (ortholog); polycystic ovary syndrome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 5 | 158676224 | 158701567 | Rat | 26 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311742 | Spata24 | spermatogenesis associated 24 | ENCODES a protein that exhibits DNA binding (ortholog); identical protein binding (ortholog); INVOLVED IN cell differentiation (inferred); DNA-templated transcription (inferred); spermatogenesis (inferred); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3 ,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil; acetamide | 18 | 27523133 | 27531375 | Rat | 64 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359156 | Spata32 | spermatogenesis associated 32 | ENCODES a protein that exhibits actin binding; INVOLVED IN spermatogenesis; ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN perinuclear region of cytoplasm; INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; copper atom | 10 | 88653309 | 88664455 | Rat | 25 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308291 | Spata9 | spermatogenesis associated 9 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A | 2 | 7197372 | 7235408 | Rat | 12 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308106 | Spindoc | spindlin interactor and repressor of chromatin binding | INVOLVED IN DNA damage response (ortholog); negative regulation of DNA-templated transcription (ortholog); FOUND IN nucleus (ortholog); site of DNA damage (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 1 | 213971995 | 213995162 | Rat | 46 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1302956 | Spink2 | serine peptidase inhibitor, Kazal type 2 | ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN acrosome assembly (ortholog); fertilization (ortholog); male germ cell proliferation (ortholog); ASSOCIATED WITH spermatogenic failure 29 (ortholog); FOUND IN acrosomal vesicle (ortholog); cytoplasm (ortholog); neuron projection (ortholog); INTERACTS WITH acrylamide; amphetamine; bisphenol A | 14 | 31321976 | 31328622 | Rat | 84 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306540 | Spink5 | serine peptidase inhibitor, Kazal type 5 | ENCODES a protein that exhibits peptidase inhibitor activity (ortholog); serine-type endopeptidase inhibitor activity (ortholog); INVOLVED IN epidermal cell differentiation (ortholog); negative regulation of antibacterial peptide biosynthetic process (ortholog); negative regulation of antibacterial peptide production (ortholog); ASSOCIATED WITH aspirin-induced respiratory disease (ortholog); centrilobular emphysema (ortholog); childhood-onset asthma (ortholog); FOUND IN cell cortex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 3,7-dihydropurine-6-thione | 18 | 36515347 | 36584038 | Rat | 121 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303077 | Spink7 | serine peptidase inhibitor, Kazal type 7 | ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN inflammatory response (ortholog); negative regulation of cytokine production involved in inflammatory response (ortholog); FOUND IN extracellular space (ortho log); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 2-hydroxypropanoic acid (ortholog); aflatoxin B1 (ortholog) | 18 | 58316302 | 58320067 | Rat | 23 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303138 | Spint1 | serine peptidase inhibitor, Kunitz type 1 | ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity; INVOLVED IN cellular response to BMP stimulus; negative regulation of neural precursor cell proliferation; positive regulation of glial cell differentiation; ASSOCIATED WITH liver cirrhosis; Alzheimer's disease (ortholog); biliary atresia (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 3 | 126685017 | 126697957 | Rat | 133 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305928 | Spmip11 | sperm microtubule inner protein 11 | INVOLVED IN flagellated sperm motility (ortholog); FOUND IN axonemal A tubule inner sheath (ortholog); sperm flagellum (ortholog); INTERACTS WITH 1,3-dinitrobenzene; bexarotene; bisphenol A | 7 | 131599977 | 131621508 | Rat | 21 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309870 | Spmip7 | sperm microtubule inner protein 7 | INVOLVED IN spermatogenesis (ortholog); INTERACTS WITH 17beta-estradiol; atrazine; bisphenol A | 14 | 90244087 | 90299294 | Rat | 22 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305356 | Srek1ip1 | SREK1-interacting protein 1 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); zinc ion binding (inferred); INVOLVED IN mRNA processing (inferred); RNA splicing (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cyclophosphamide | 2 | 37709712 | 37733391 | Rat | 73 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306564 | Srl | sarcalumenin | ENCODES a protein that exhibits GTP binding (inferred); INVOLVED IN response to muscle activity involved in regulation of muscle adaptation (ortholog); store-operated calcium entry (ortholog); ASSOCIATED WITH Rubinstein-Taybi syndrome (ortholog); FOUND IN endomembrane system (inferred); sarcoplasmic reticulum lumen (inferred); sarcoplasmic reticulum membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; alpha-Zearalanol | 10 | 11540365 | 11584506 | Rat | 67 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311504 | Srpra | SRP receptor subunit alpha | ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); nucleotide binding (inferred); INVOLVED IN intracellular protein transport (inferred); SRP-dependent cotranslational protein targeting to membrane (inferred); ASSOCIATED WITH Shwachman-Diamond syndrome (ortholog); FO UND IN membrane (ortholog); signal recognition particle receptor complex (ortholog); INTERACTS WITH (+)-schisandrin B; 2,6-dinitrotoluene; bisphenol A | 8 | 41818199 | 41824292 | Rat | 117 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304698 | Srprb | SRP receptor subunit beta | ENCODES a protein that exhibits ubiquitin protein ligase binding; FOUND IN cytoplasm (ortholog); cytoplasmic microtubule (ortholog); membrane (ortholog); INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; amiodarone | 8 | 112647577 | 112661524 | Rat | 108 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310259 | Ssna1 | SS nuclear autoantigen 1 | ENCODES a protein that exhibits identical protein binding (ortholog); microtubule binding (ortholog); INVOLVED IN axon arborization (ortholog); axon extension (ortholog); axonogenesis (ortholog); FOUND IN axon (ortholog); axoneme (ortholog); centriole (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodi benzodioxine; 2,4,6-trinitrotoluene; 4,4'-sulfonyldiphenol | 3 | 28483107 | 28484571 | Rat | 88 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311497 | Stam2 | signal transducing adaptor molecule 2 | ENCODES a protein that exhibits phosphatidylinositol binding (inferred); ubiquitin binding (inferred); INVOLVED IN macroautophagy (inferred); multivesicular body assembly (inferred); protein transport (inferred); PARTICIPATES IN interleukin-2 signaling pathway; endocytosis pathway; Jak-Stat signalin g pathway; FOUND IN cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; bisphenol A | 3 | 57597557 | 57643915 | Rat | 89 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308633 | Stard3nl | STARD3 N-terminal like | ENCODES a protein that exhibits cholesterol binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN vesicle tethering to endoplasmic reticulum (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); endoplasmic reticulum-endosome membrane contact site (ortholog); endoso me (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 17 | 50278859 | 50312864 | Rat | 75 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309475 | Stard4 | StAR-related lipid transfer domain containing 4 | ENCODES a protein that exhibits cholesterol binding (ortholog); cholesterol transfer activity (ortholog); INVOLVED IN cholesterol import (ortholog); cholesterol transport involved in cholesterol storage (ortholog); intracellular cholesterol transport (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1-benzylpiperazine; 17beta-estradiol | 18 | 25088831 | 25104172 | Rat | 187 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310622 | Stox1 | storkhead box 1 | ENCODES a protein that exhibits RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to nitrosative stress (ortholog); inner ear development (ortholog); negative regulation of gene expression (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Cardiomegaly (ortholog); pre-eclampsia (ortholog); FOUND IN cell cortex (ortholog); centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH bisphenol A; methoxychlor; paracetamol | 20 | 31140993 | 31209126 | Rat | 124 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307030 | Strn4 | striatin 4 | ENCODES a protein that exhibits protein domain specific binding; protein-containing complex binding; armadillo repeat domain binding (ortholog); INVOLVED IN regulation of modification of postsynaptic structure; negative regulation of hippo signaling (ortholog); FOUND IN dendritic spine; GABA-ergic s ynapse; glutamatergic synapse; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 86614193 | 86639959 | Rat | 82 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311563 | Stt3b | STT3 oligosaccharyltransferase complex catalytic subunit B | ENCODES a protein that exhibits dolichyl-diphosphooligosaccharide-protein glycotransferase activity (ortholog); INVOLVED IN ERAD pathway (ortholog); glycoprotein catabolic process (ortholog); post-translational protein modification (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degrada tion pathway; N-linked glycan biosynthetic pathway; ASSOCIATED WITH congenital disorder of glycosylation Ix (ortholog); FOUND IN endoplasmic reticulum (ortholog); oligosaccharyltransferase complex (ortholog); oligosaccharyltransferase complex B (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil | 8 | 123806836 | 123872179 | Rat | 117 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305845 | Styxl1 | serine/threonine/tyrosine interacting-like 1 | ENCODES a protein that exhibits phosphatase inhibitor activity (ortholog); protein phosphatase binding (ortholog); pseudophosphatase activity (ortholog); INVOLVED IN negative regulation of stress granule assembly (ortholog); positive regulation of intrinsic apoptotic signaling pathway (ortholog); po sitive regulation of neuron projection development (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,4-dinitrotoluene | 12 | 26544059 | 26576365 | Rat | 99 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309397 | Sucla2 | succinate-CoA ligase ADP-forming subunit beta | ENCODES a protein that exhibits succinate-CoA ligase (ADP-forming) activity; acid-thiol ligase activity (ortholog); INVOLVED IN succinate metabolic process; succinyl-CoA metabolic process; tricarboxylic acid cycle; PARTICIPATES IN citric acid cycle pathway; propanoate metabolic pathway; ASSOCIATED W ITH Developmental Disabilities (ortholog); genetic disease (ortholog); mitochondrial DNA depletion syndrome (ortholog); FOUND IN catalytic complex (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 15 | 55161894 | 55215031 | Rat | 153 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306372 | Supt4h1 | SPT4 homolog, DSIF elongation factor subunit | ENCODES a protein that exhibits protein heterodimerization activity (ortholog); RNA polymerase inhibitor activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription, elongation (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulati on of DNA-templated transcription, elongation (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription elongation pathway; FOUND IN DSIF complex (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 10 | 73036560 | 73042821 | Rat | 65 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305565 | Supv3l1 | Suv3 like RNA helicase | ENCODES a protein that exhibits 3'-5' RNA helicase activity (ortholog); 3'-5'-RNA exonuclease activity (ortholog); DNA binding (ortholog); INVOLVED IN DNA recombination (ortholog); mitochondrial mRNA catabolic process (ortholog); mitochondrial mRNA surveillance (ortholog); ASSOCIATED WITH alopecia ( ortholog); ichthyosis (ortholog); Sarcopenia (ortholog); FOUND IN mitochondrial degradosome (ortholog); mitochondrial matrix (ortholog); mitochondrial nucleoid (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 20 | 30921248 | 30941779 | Rat | 140 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310933 | Susd3 | sushi domain containing 3 | FOUND IN plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol | 17 | 15607259 | 15623322 | Rat | 99 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311232 | Svbp | small vasohibin binding protein | ENCODES a protein that exhibits microtubule binding (ortholog); peptidase activator activity (ortholog); INVOLVED IN axon development (ortholog); brain development (ortholog); negative regulation of endothelial cell migration (ortholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disab ility (ortholog); microcephaly (ortholog); FOUND IN apical part of cell (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 5 | 138091773 | 138099048 | Rat | 73 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311054 | Svs6 | seminal vesicle secretory protein 6 | FOUND IN extracellular region (inferred); INTERACTS WITH 17beta-estradiol 3-benzoate; bisphenol A; decabromodiphenyl ether | 3 | 173391856 | 173399363 | Rat | 6 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308026 | Swsap1 | SWIM-type zinc finger 7 associated protein 1 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN double-strand break repair via homologous recombination (ortholog); protein stabilization (ortholog); FOUND IN Shu complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodiox ine; bisphenol A; glafenine | 8 | 28762753 | 28765281 | Rat | 31 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311867 | Syce2 | synaptonemal complex central element protein 2 | ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); ATP binding (inferred); ligase activity (inferred); INVOLVED IN phenylalanyl-tRNA aminoacylation (inferred); synaptonemal complex assembly (inferred); translation (inferred); FOUND IN central element (ortholog); chromosome (o rtholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 19 | 40173713 | 40195959 | Rat | 81 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307970 | Sync | syncoilin, intermediate filament protein | INVOLVED IN intermediate filament-based process (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); neuromuscular junction (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; 4,4'-sulfonyldiphenol | 5 | 146915715 | 146940547 | Rat | 86 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304580 | Syne4 | spectrin repeat containing nuclear envelope family member 4 | INVOLVED IN establishment of epithelial cell apical/basal polarity (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness 76 (ortholog); nonsyndromic deafness (ortholog); FOUND IN nuclear outer membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 94696866 | 94701230 | Rat | 69 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305698 | Taf1a | TATA-box binding protein associated factor, RNA polymerase I subunit A | ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN regulation of DNA-templated transcription (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; ASSOCIATED WITH dilated cardiomyopathy (ortholog); familial restrictive cardiomyopathy 6 (ortholog); FOUND IN RNA polymera se transcription factor SL1 complex (ortholog); INTERACTS WITH (+)-schisandrin B; acrylamide; bisphenol A | 13 | 97543772 | 97579742 | Rat | 77 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305658 | Taf1c | TATA-box binding protein associated factor, RNA polymerase 1 subunit C | ENCODES a protein that exhibits RNA polymerase I core promoter sequence-specific DNA binding (ortholog); RNA polymerase I general transcription initiation factor activity (ortholog); INVOLVED IN regulation of DNA-templated transcription (ortholog); PARTICIPATES IN RNA polymerase I transcription path way; ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN fibrillar center (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 19 | 64561079 | 64567599 | Rat | 89 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308423 | Taf8 | TATA-box binding protein associated factor 8 | ENCODES a protein that exhibits protein heterodimerization activity (inferred); INVOLVED IN DNA-templated transcription open complex formation (ortholog); inner cell mass cell proliferation (ortholog); maintenance of protein location in nucleus (ortholog); PARTICIPATES IN RNA polymerase II transcrip tion initiation pathway; ASSOCIATED WITH microcephaly (ortholog); NEURODEVELOPMENTAL DISORDER WITH SEVERE MOTOR IMPAIRMENT, ABSENT LANGUAGE, CEREBRAL HYPOMYELINATION, AND BRAIN ATROPHY (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; acrylamide; bisphenol A | 9 | 20989554 | 21009541 | Rat | 76 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307375 | Tarbp2 | Tarbp2 subunit of RISC loading complex | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); enzyme binding (ortholog); identical protein binding (ortholog); INVOLVED IN global gene silencing by mRNA cleavage (ortholog); miRNA processing (ortholog); multicellular organism growth (ortholog); PARTICIPATES IN microRNA path way; ASSOCIATED WITH Microsatellite Instability (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); RISC complex (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 135527710 | 135532826 | Rat | 166 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304958 | Tbc1d19 | TBC1 domain family, member 19 | INVOLVED IN regulation of cilium assembly (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acetamide | 14 | 61297193 | 61413106 | Rat | 53 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308880 | Tbcel | tubulin folding cofactor E-like | FOUND IN cytoskeleton (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 8 | 51692660 | 51751560 | Rat | 80 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309880 | Tcea1 | transcription elongation factor A1 | ENCODES a protein that exhibits transcription elongation factor activity (ortholog); INVOLVED IN positive regulation of mRNA catabolic process; erythrocyte differentiation (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN RNA polymerase II transcription elong ation pathway; FOUND IN nucleoplasm (ortholog); transcription factor TFIID complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide | 5 | 19414351 | 19466629 | Rat | 105 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302974 | Tcf19 | transcription factor 19 | INVOLVED IN G1/S transition of mitotic cell cycle (ortholog); regulation of gene expression (ortholog); type B pancreatic cell proliferation (ortholog); ASSOCIATED WITH Colonic Neoplasms (ortholog); hepatocellular carcinoma (ortholog); sensorineural hearing loss (ortholog); FOUND IN nucleus (ortholo g); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 20 | 3223464 | 3227569 | Rat | 174 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308305 | Tchhl1 | trichohyalin-like 1 | ENCODES a protein that exhibits calcium ion binding (inferred); transition metal ion binding (inferred); ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); INTERACTS WITH bisphenol A; gentamycin; lidocaine | 2 | 181818424 | 181821666 | Rat | 26 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310214 | Tdh | L-threonine dehydrogenase | ENCODES a protein that exhibits identical protein binding (ortholog); L-threonine 3-dehydrogenase activity (ortholog); INVOLVED IN L-threonine catabolic process (ortholog); PARTICIPATES IN glycine, serine and threonine metabolic pathway; FOUND IN mitochondrion (ortholog); INTERACTS WITH 6-propyl-2-t hiouracil; acetamide; amitrole | 15 | 41915766 | 41929307 | Rat | 53 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306873 | Tecpr1 | tectonin beta-propeller repeat containing 1 | ENCODES a protein that exhibits phosphatidylinositol-3-phosphate binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); macroautophagy (ortholog); ASSOCIATED WITH esophageal atresia/tracheoesophageal fistula (ortholog); FOUND IN autophagosome membrane (ortholog); early endosome membrane (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 1-benzylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide | 12 | 15504456 | 15534541 | Rat | 89 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311078 | Ten1 | TEN1 subunit of CST complex | ENCODES a protein that exhibits telomeric DNA binding (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomerase (ortholog); ASSOCIATED WITH dyskeratosis congenita (ortholog); FOUND IN chromosome, telomeric region (ortholog); CST complex (ortholog); nucleoplasm (ortholog); IN TERACTS WITH (R,R,R)-alpha-tocopherol; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 10 | 101930212 | 101951932 | Rat | 57 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311574 | Terf1 | telomeric repeat binding factor 1 | ENCODES a protein that exhibits ankyrin repeat binding (ortholog); DNA binding, bending (ortholog); double-stranded telomeric DNA binding (ortholog); INVOLVED IN response to xenobiotic stimulus; meiotic telomere clustering (ortholog); negative regulation of DNA replication (ortholog); ASSOCIATED WIT H breast cancer (ortholog); squamous cell carcinoma (ortholog); stomach cancer (ortholog); FOUND IN chromosome, telomeric region (ortholog); nuclear body (ortholog); nuclear telomere cap complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 5 | 8226345 | 8255614 | Rat | 184 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310881 | Terf2 | telomeric repeat binding factor 2 | ENCODES a protein that exhibits double-stranded telomeric DNA binding (ortholog); enzyme binding (ortholog); G-rich strand telomeric DNA binding (ortholog); INVOLVED IN axonal transport of messenger ribonucleoprotein complex; in utero embryonic development (ortholog); negative regulation of cellular senescence (ortholog); ASSOCIATED WITH adult T-cell leukemia/lymphoma (ortholog); xeroderma pigmentosum (ortholog); FOUND IN chromosome, telomeric region (ortholog); male germ cell nucleus (ortholog); nuclear body (ortholog); INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; 2,2',4,4'-Tetrabromodiphenyl ether | 19 | 51887221 | 51915756 | Rat | 205 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305365 | Tesl | testis derived transcript-like | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); FOUND IN cytoplasm (inferred); focal adhesion (inferred); INTERACTS WITH bisphenol A; rotenone; trichloroethene | X | 119485153 | 119498721 | Rat | 8 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305437 | Tex14 | testis expressed 14, intercellular bridge forming factor | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN attachment of spindle microtubules to kinetochore (ortholog); cellular response to leukemia inhibitory factor (ortholog); intercellular bridge organization (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer synd rome (ortholog); prostate cancer (ortholog); spermatogenic failure 23 (ortholog); FOUND IN intercellular bridge (ortholog); kinetochore (ortholog); midbody (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 3',5'-cyclic AMP; allethrin | 10 | 72729017 | 72859697 | Rat | 100 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311266 | Tex15 | testis expressed 15, meiosis and synapsis associated | INVOLVED IN DNA methylation-dependent constitutive heterochromatin formation (ortholog); fertilization (ortholog); homeostasis of number of cells within a tissue (ortholog); ASSOCIATED WITH myoepithelioma (ortholog); spermatogenic failure 1 (ortholog); spermatogenic failure 25 (ortholog); FOUND IN c ytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; bisphenol A | 16 | 65302049 | 65362065 | Rat | 93 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306995 | Tex55 | testis expressed 55 | FOUND IN nucleus (ortholog); sperm flagellum (ortholog); INTERACTS WITH bisphenol A; aflatoxin B1 (ortholog); arsane (ortholog) | 11 | 75432861 | 75449144 | Rat | 13 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307537 | Tex56p | testis expressed 56 | ENCODES a protein that exhibits nucleic acid binding (inferred); INTERACTS WITH lidocaine; thioacetamide; sodium arsenite (ortholog) | 17 | 30135241 | 30171956 | Rat | 6 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311449 | Tfip11 | tuftelin interacting protein 11 | ENCODES a protein that exhibits nucleic acid binding (inferred); INVOLVED IN negative regulation of protein-containing complex assembly (ortholog); spliceosomal complex disassembly (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); chromosome, telomeric region (ortholog); extracellular ma trix (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 12 | 49960025 | 49972257 | Rat | 84 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307589 | Thap1 | THAP domain containing 1 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN DNA-templated transcription (ortholog); endothelial cell proliferation (ortholog); nega tive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH dystonia (ortholog); genetic disease (ortholog); Multiple mitochondrial dysfunctions syndrome 9B (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; cadmium dichloride | 16 | 72608096 | 72612690 | Rat | 97 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308109 | Thap3 | THAP domain containing 3 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 5 | 167771209 | 167776878 | Rat | 60 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310094 | Thap6 | THAP domain containing 6 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); FOUND IN microtubule cytoskeleton (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; 2-palmitoylglycerol (ortholog) | 14 | 16385579 | 16397735 | Rat | 26 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308061 | Thap7 | THAP domain containing 7 | ENCODES a protein that exhibits C2H2 zinc finger domain binding (ortholog); general transcription initiation factor binding (ortholog); histone deacetylase binding (ortholog); INVOLVED IN chromatin organization (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regul ation of transcription by RNA polymerase II (ortholog); FOUND IN chromatin (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 11 | 96986720 | 96990375 | Rat | 77 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309144 | Thnsl2 | threonine synthase-like 2 | ENCODES a protein that exhibits phosphatase activity (ortholog); pyridoxal phosphate binding (ortholog); serine binding (ortholog); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 104671305 | 104691084 | Rat | 110 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306878 | Thumpd2 | THUMP domain 2 tRNA and snRNA guanosine methyltransferase | ENCODES a protein that exhibits U6 snRNA (guanine-N(2))-methyltransferase activity (ortholog); INVOLVED IN regulation of alternative mRNA splicing, via spliceosome (ortholog); FOUND IN nucleus (ortholog); tRNA methyltransferase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2, 4-dinitrotoluene; 6-propyl-2-thiouracil | 6 | 19677039 | 19728947 | Rat | 55 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307455 | Tiam1 | TIAM Rac1 associated GEF 1 | ENCODES a protein that exhibits microtubule binding; receptor tyrosine kinase binding; ephrin receptor binding (ortholog); INVOLVED IN activation of GTPase activity; cardiac muscle hypertrophy; neuron projection extension; PARTICIPATES IN brain-derived neurotrophic factor signaling pathway; E-cadher in signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Mouth Neoplasms (ortholog); neurodevelopmental disorder with language delay and seizures (ortholog); FOUND IN axonal growth cone; dendritic spine; extrinsic component of postsynaptic density membrane; INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 11 | 42517527 | 42866280 | Rat | 213 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359571 | Timd2 | T-cell immunoglobulin and mucin domain containing 2 | ENCODES a protein that exhibits ferritin receptor activity (ortholog); INVOLVED IN iron ion transport (ortholog); FOUND IN cell surface (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amitrole; bisphenol A | 10 | 31561563 | 31602515 | Rat | 66 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309188 | Timm29 | translocase of inner mitochondrial membrane 29 | ENCODES a protein that exhibits protein transporter activity (ortholog); INVOLVED IN protein insertion into mitochondrial inner membrane (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial intermembrane space (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrac hlorodibenzodioxine; aconitine; aflatoxin B1 | 8 | 28421370 | 28424339 | Rat | 48 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311666 | Tlnrd1 | talin rod domain containing 1 | ENCODES a protein that exhibits actin binding (ortholog); identical protein binding (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN stress fiber (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 1 | 147273475 | 147275494 | Rat | 83 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305442 | Tm2d1 | TM2 domain containing 1 | ENCODES a protein that exhibits amyloid-beta binding (ortholog); G protein-coupled receptor activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 5 | 118136299 | 118177639 | Rat | 77 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309263 | Tmco6 | transmembrane and coiled-coil domains 6 | ENCODES a protein that exhibits nuclear import signal receptor activity (inferred); INVOLVED IN protein import into nucleus (inferred); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; bisphenol A | 18 | 28623269 | 28629864 | Rat | 55 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303037 | Tmem106b | transmembrane protein 106B | ENCODES a protein that exhibits ATPase binding (ortholog); INVOLVED IN dendrite morphogenesis (ortholog); lysosomal lumen acidification (ortholog); lysosomal protein catabolic process (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Frontotemporal Lobar Degeneration (ortholog); genetic disease (orth olog); FOUND IN endosome (ortholog); lysosomal membrane (ortholog); lysosome (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 42294074 | 42313426 | Rat | 134 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311530 | Tmem108 | transmembrane protein 108 | INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); dendrite extension (ortholog); dentate gyrus development (ortholog); FOUND IN axon (ortholog); early endosome (ortholog); endosome membrane (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; bisphenol A | 8 | 112944925 | 113238996 | Rat | 104 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307573 | Tmem119 | transmembrane protein 119 | INVOLVED IN BMP signaling pathway (ortholog); endochondral ossification (ortholog); negative regulation of bone resorption (ortholog); FOUND IN endoplasmic reticulum (ortholog); plasma membrane (ortholog); INTERACTS WITH all-trans-retinoic acid; bis(2-ethylhexyl) phthalate; bisphenol A | 12 | 48489157 | 48496214 | Rat | 117 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311474 | Tmem120a | transmembrane protein 120A | ENCODES a protein that exhibits coenzyme A binding (ortholog); monoatomic ion channel activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); detection of mechanical stimulus involved in sensory perception of pain (ortholog); fat cell differentiation (ortholog); FOUND IN endopl asmic reticulum (ortholog); nuclear inner membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 12 | 26578859 | 26587524 | Rat | 147 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311937 | Tmem125 | transmembrane protein 125 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 5 | 137348545 | 137349949 | Rat | 63 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309744 | Tmem127 | transmembrane protein 127 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN endosome organization (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of TOR signaling (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); acute promyelocytic leuk emia (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (ortholog); early endosome (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 3 | 134919416 | 134932210 | Rat | 79 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310481 | Tmem128 | transmembrane protein 128 | INTERACTS WITH alpha-Zearalanol; bisphenol A; methoxychlor | 14 | 76751848 | 76761576 | Rat | 42 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309266 | Tmem131 | transmembrane protein 131 | ENCODES a protein that exhibits collagen binding (ortholog); INVOLVED IN collagen biosynthetic process (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 9 | 46512328 | 46658624 | Rat | 74 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305824 | Tmem134 | transmembrane protein 134 | FOUND IN cytosol (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 1 | 210848761 | 210857735 | Rat | 63 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306983 | Tmem165 | transmembrane protein 165 | ENCODES a protein that exhibits antiporter activity (inferred); metal ion transmembrane transporter activity (inferred); INVOLVED IN calcium ion transport (ortholog); Golgi calcium ion transport (ortholog); intracellular calcium ion homeostasis (ortholog); ASSOCIATED WITH congenital disorder of glyc osylation (ortholog); congenital disorder of glycosylation type IIk (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cis-Golgi network membrane (ortholog); endosome membrane (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 14 | 32347688 | 32372916 | Rat | 115 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306282 | Tmem186l1 | transmembrane protein 186l1 | FOUND IN mitochondrial inner membrane (inferred); INTERACTS WITH bisphenol A | 7 | 55439204 | 55441385 | Rat | 3 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1309341 | Tmem192 | transmembrane protein 192 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); FOUND IN endoplasmic reticulum (ortholog); endosome (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,5-hexanedione; atrazine; bisphenol A | 16 | 29506658 | 29527553 | Rat | 65 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311364 | Tmem218 | transmembrane protein 218 | ASSOCIATED WITH Joubert syndrome (ortholog); Joubert Syndrome 39 (ortholog); Meckel syndrome 4 (ortholog); FOUND IN cilium (inferred); membrane (inferred); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 45113368 | 45128739 | Rat | 73 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309576 | Tmem220 | transmembrane protein 220 | INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 52218782 | 52229302 | Rat | 39 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306153 | Tmem231 | transmembrane protein 231 | INVOLVED IN camera-type eye development (ortholog); cilium assembly (ortholog); embryonic digit morphogenesis (ortholog); ASSOCIATED WITH CAKUT (ortholog); ciliopathy (ortholog); Desbuquois dysplasia (ortholog); FOUND IN ciliary membrane (ortholog); ciliary transition zone (ortholog); membrane (orth olog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 19 | 56792329 | 56813515 | Rat | 85 | PANTHER | gene, protein-coding, INFERRED [RefSeq] |
| 1306705 | Tmem237 | transmembrane protein 237 | INVOLVED IN cilium assembly (ortholog); regulation of Wnt signaling pathway (ortholog); ASSOCIATED WITH fundus dystrophy (ortholog); genetic disease (ortholog); Joubert syndrome (ortholog); FOUND IN ciliary transition zone (ortholog); cilium (ortholog); cone photoreceptor outer segment (ortholog); I NTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 9 | 68027481 | 68066731 | Rat | 95 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304595 | Tmem268 | transmembrane protein 268 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amitrole | 5 | 81990314 | 82016970 | Rat | 60 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306090 | Tmem30c | transmembrane protein 30C | INVOLVED IN aminophospholipid translocation (inferred); FOUND IN membrane (inferred); INTERACTS WITH bisphenol A; glyphosate; trichloroethene | 11 | 56708788 | 56727633 | Rat | 24 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307118 | Tmem42 | transmembrane protein 42 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3-chloropropane-1,2-diol | 8 | 131551616 | 131554749 | Rat | 75 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305557 | Tmem59l | transmembrane protein 59-like | INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); ASSOCIATED WITH ovarian cyst (ortholog); FOUND IN Golgi membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; all-trans-retinoic acid | 16 | 18975217 | 18979354 | Rat | 57 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308850 | Tmem72 | transmembrane protein 72 | FOUND IN cytoplasm (ortholog); early endosome membrane (ortholog); nucleus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; aflatoxin B1; bisphenol A | 4 | 151620696 | 151645989 | Rat | 38 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309886 | Tmem79 | transmembrane protein 79 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cornification (ortholog); cuticle development (ortholog); epithelial cell maturation (ortholog); ASSOCIATED WITH atopic dermatitis (ortholog); Charcot-Marie-Tooth disease type 2 (ortholog); FOUND IN cytoplasm (ortholog ); lysosomal membrane (ortholog); trans-Golgi network membrane (ortholog); INTERACTS WITH acrylamide; bisphenol A; cadmium dichloride | 2 | 176096092 | 176100996 | Rat | 89 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307922 | Tmem9 | transmembrane protein 9 | INVOLVED IN endosomal lumen acidification (ortholog); lysosomal lumen acidification (ortholog); positive regulation of canonical Wnt signaling pathway (ortholog); FOUND IN late endosome (ortholog); lysosomal membrane (ortholog); lysosome (ortholog); INTERACTS WITH (+)-schisandrin B; 2,2',5,5'-tetrac hlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 13 | 50008829 | 50027556 | Rat | 96 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307423 | Tmem97 | transmembrane protein 97 | ENCODES a protein that exhibits cholesterol binding (ortholog); oxysterol binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); positive regulation of lipoprotein transport (ortholog); positive regulation of wound healing (ortholog); FOUND IN endoplasmic reticulum (ortholog); lysosome (ortholog); nuclear membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 10 | 63936276 | 63945359 | Rat | 198 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306351 | Tmtc3 | transmembrane O-mannosyltransferase targeting cadherins 3 | ENCODES a protein that exhibits dolichyl-phosphate-mannose-protein mannosyltransferase activity (ortholog); INVOLVED IN bud outgrowth involved in lung branching (ortholog); cell differentiation (ortholog); lung alveolus development (ortholog); ASSOCIATED WITH genetic disease (ortholog); lissencephal y (ortholog); lissencephaly 8 (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 7 | 37151456 | 37196550 | Rat | 117 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305146 | Tmx4 | thioredoxin-related transmembrane protein 4 | ASSOCIATED WITH congenital myasthenic syndrome 18 (ortholog); developmental and epileptic encephalopathy 12 (ortholog); FOUND IN endoplasmic reticulum (ortholog); nuclear inner membrane (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,4-dinitrotoluene | 3 | 142309026 | 142352415 | Rat | 87 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307308 | Tnfrsf21 | TNF receptor superfamily member 21 | INVOLVED IN axonal fasciculation; adaptive immune response (ortholog); apoptotic process (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Gliosis (ortholog); Prostatic Neoplasms (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether | 9 | 25376400 | 25451323 | Rat | 258 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310917 | Tns2 | tensin 2 | ENCODES a protein that exhibits identical protein binding (ortholog); kinase binding (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN cellular homeostasis (ortholog); collagen metabolic process (ortholog); kidney development (ortholog); ASSOCIATED WITH nephrotic syndrome (or tholog); Pierson syndrome (ortholog); FOUND IN focal adhesion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 7 | 135108401 | 135126505 | Rat | 132 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303049 | Tomm70 | translocase of outer mitochondrial membrane 70 | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN negative regulation of cell growth involved in cardiac muscle cell development; positive regulation of protein targeting to mitochondrion; protein targeting to mitochondrion; PARTICIPATES IN alpha-helical insertion pathway of mitochondrial protein import; beta-barrel pathway of mitochondrial protein import; carrier pathway of mitochondrial protein import; ASSOCIATED WITH Cardiomegaly; congestive heart failure; Experimental Diabetes Mellitus; FOUND IN mitochondrial outer membrane; mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | 11 | 56847837 | 56886302 | Rat | 149 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307483 | Tonsl | tonsoku-like, DNA repair protein | ENCODES a protein that exhibits histone binding (ortholog); histone reader activity (ortholog); INVOLVED IN double-strand break repair via homologous recombination (ortholog); protein localization to chromatin (ortholog); replication fork processing (ortholog); ASSOCIATED WITH Desbuquois dysplasia ( ortholog); genetic disease (ortholog); hepatocellular carcinoma (ortholog); FOUND IN DNA replication factor A complex (ortholog); FACT complex (ortholog); MCM complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 110226696 | 110241459 | Rat | 119 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303177 | Top1mt | DNA topoisomerase I mitochondrial | ENCODES a protein that exhibits DNA binding (inferred); DNA topoisomerase activity (inferred); DNA topoisomerase type I (single strand cut, ATP-independent) activity (inferred); INVOLVED IN DNA topological change (inferred); ASSOCIATED WITH sensorineural hearing loss (ortholog); FOUND IN mitochondri al nucleoid (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A | 7 | 109223269 | 109248855 | Rat | 78 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308019 | Tor4a | torsin family 4, member A | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); nucleotide binding (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (inferred); endomembrane system (inferred); membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 3 | 28402454 | 28406141 | Rat | 90 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308395 | Tp53i11 | tumor protein p53 inducible protein 11 | FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 3 | 99600213 | 99615462 | Rat | 122 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311779 | Tpcn2 | two pore segment channel 2 | ENCODES a protein that exhibits calcium channel activity (ortholog); identical protein binding (ortholog); intracellularly phosphatidylinositol-3,5-bisphosphate-gated monatomic cation channel activity (ortholog); INVOLVED IN response to vitamin D; calcium-mediated signaling (ortholog); endocytosis i nvolved in viral entry into host cell (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH brain infarction; Marfanoid Mental Retardation Syndrome, Autosomal (ortholog); Skin/Hair/Eye Pigmentation, Variation In, 10 (ortholog); FOUND IN endolysosome membrane (ortholog); endosome membrane (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 1 | 209845827 | 209875561 | Rat | 159 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309761 | Traip | TRAF-interacting protein | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of interferon-beta production (ortholog); negative regulation of tumo r necrosis factor-mediated signaling pathway (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 1H-pyrazole | 8 | 117520476 | 117540253 | Rat | 147 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307639 | Trarg1 | trafficking regulator of GLUT4 (SLC2A4) 1 | INVOLVED IN cellular response to insulin stimulus (ortholog); endosome to plasma membrane protein transport (ortholog); glucose import in response to insulin stimulus (ortholog); FOUND IN cytoplasmic vesicle membrane; perinuclear region of cytoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A | 10 | 62019281 | 62039666 | Rat | 76 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306292 | Trdmt1 | tRNA aspartic acid methyltransferase 1 | ENCODES a protein that exhibits tRNA (cytidine-5-)-methyltransferase activity (ortholog); tRNA methyltransferase activity (ortholog); INVOLVED IN response to amphetamine; tRNA methylation (ortholog); tRNA modification (ortholog); PARTICIPATES IN homocysteine metabolic pathway; methionine cycle/metab olic pathway; cysteine and methionine metabolic pathway; FOUND IN cytoplasm (ortholog); INTERACTS WITH aflatoxin B1; allethrin; bisphenol A | 17 | 81510740 | 81554036 | Rat | 103 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308516 | Trip13 | thyroid hormone receptor interactor 13 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN double-strand break repair (ortholog); female meiosis I (ortholog); male meiosis I (ortholog); ASSOCIATED WITH Aneuploidy (ortholog); COVID-19 (ortholog); Germ Cell and Embryonal Neoplasms (ortholog); FOUND IN male ger m cell nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil | 1 | 31185700 | 31230638 | Rat | 200 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307890 | Trmt1l | tRNA methyltransferase 1-like | ENCODES a protein that exhibits tRNA (guanine(27)-N2)-dimethyltransferase activity (ortholog); INVOLVED IN adult behavior (ortholog); adult locomotory behavior (ortholog); tRNA N2-guanine methylation (ortholog); FOUND IN nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodib enzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 13 | 66060186 | 66093247 | Rat | 99 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308857 | Trnt1 | tRNA nucleotidyl transferase 1 | ENCODES a protein that exhibits CCA tRNA nucleotidyltransferase activity (ortholog); CCACCA tRNA nucleotidyltransferase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN mitochondrial tRNA 3'-end processing (ortholog); rescue of stalled cytosolic ribosome (ortholog); tRN A 3'-terminal CCA addition (ortholog); PARTICIPATES IN RNA transport pathway; ASSOCIATED WITH fundus dystrophy (ortholog); genetic disease (ortholog); optic atrophy (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 4 | 141236937 | 141259700 | Rat | 93 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303284 | Trpa1 | transient receptor potential cation channel, subfamily A, member 1 | ENCODES a protein that exhibits osmolarity-sensing monoatomic cation channel activity; voltage-gated calcium channel activity; calcium channel activity (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol; cellular response to caffeine; cellular response to carbon dioxide; ASSOCIATE D WITH Abdominal Pain; asthma; Cold Hypersensitivity; FOUND IN apical plasma membrane; axon; plasma membrane (ortholog); INTERACTS WITH 3-phenylprop-2-enal; 4-hydroxynon-2-enal; aconitine | 5 | 9163060 | 9217325 | Rat | 320 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309914 | Trpc4ap | transient receptor potential cation channel, subfamily C, member 4 associated protein | ENCODES a protein that exhibits phosphatase binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN hair follicle maturation (ortholog); protein ubiquitination (ortholog); ubiquitin-dependent protein catabolic process (ortholog); FOUND IN Cul4-RING E3 ubiquitin l igase complex (ortholog); Cul4A-RING E3 ubiquitin ligase complex (ortholog); cytosol (ortholog); INTERACTS WITH bisphenol A; C60 fullerene; cocaine | 3 | 164582146 | 164653123 | Rat | 74 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311883 | Trps1 | transcriptional repressor GATA binding 1 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); protein domain specific binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cell surface receptor protein serin e/threonine kinase signaling pathway (ortholog); chondrocyte differentiation (ortholog); hair follicle development (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); bone development disease (ortholog); brachydactyly (ortholog); FOUND IN chromatin (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 3,4-methylenedioxymethamphetamine; acetamide | 7 | 83806121 | 84032609 | Rat | 149 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305446 | Trrap | transformation/transcription domain-associated protein | ENCODES a protein that exhibits chromatin binding; transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regulation of D NA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH acrylamide; amphetamine; bisphenol A | 12 | 14851758 | 14941444 | Rat | 119 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304953 | Tsacc | TSSK6 activating co-chaperone | ENCODES a protein that exhibits protein-folding chaperone binding (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; cadmium dichloride | 2 | 176053672 | 176063412 | Rat | 28 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308584 | Tsen15 | tRNA splicing endonuclease subunit 15 | ENCODES a protein that exhibits nucleic acid binding (inferred); INVOLVED IN tRNA-type intron splice site recognition and cleavage (ortholog); PARTICIPATES IN tRNA maturation pathway; ASSOCIATED WITH Developmental Disabilities (ortholog); genetic disease (ortholog); pontocerebellar hypoplasia type 2 F (ortholog); FOUND IN nucleolus (inferred); nucleus (inferred); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; bisphenol A | 13 | 67040134 | 67055509 | Rat | 74 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359604 | Ttc1 | tetratricopeptide repeat domain 1 | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN positive regulation of neuroinflammatory response (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 10 | 28703763 | 28728910 | Rat | 65 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303264 | Ttc12 | tetratricopeptide repeat domain 12 | INVOLVED IN axonemal dynein complex assembly (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); alcohol dependence (ortholog); Asthenozoospermia (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodi benzodioxine; 6-propyl-2-thiouracil; acetamide | 8 | 58696381 | 58743857 | Rat | 101 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310186 | Ttc13 | tetratricopeptide repeat domain 13 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; acrylamide | 19 | 69534989 | 69589590 | Rat | 62 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305410 | Ttc17 | tetratricopeptide repeat domain 17 | INVOLVED IN actin filament polymerization (ortholog); cilium organization (ortholog); FOUND IN cytoplasm; actin cytoskeleton (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; furan | 3 | 100718820 | 100829464 | Rat | 101 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304840 | Ttc34 | tetratricopeptide repeat domain 34 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; C60 fullerene | 5 | 170693410 | 170711215 | Rat | 20 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1308529 | Ttc4 | tetratricopeptide repeat domain 4 | ENCODES a protein that exhibits Hsp90 protein binding (inferred); INVOLVED IN defense response to virus (ortholog); innate immune response (ortholog); FOUND IN cytoplasm (ortholog); intermediate filament cytoskeleton (ortholog); nucleus (ortholog); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; acr ylamide; bisphenol A | 5 | 126673535 | 126691203 | Rat | 48 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307769 | Ttc8 | tetratricopeptide repeat domain 8 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN axon guidance (ortholog); camera-type eye photoreceptor cell differentiation (ortholog); cilium assembly (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Bardet-Bi edl syndrome 8 (ortholog); fundus dystrophy (ortholog); FOUND IN BBSome (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride | 6 | 123927657 | 124025354 | Rat | 129 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305319 | Ttll12 | tubulin tyrosine ligase like 12 | ENCODES a protein that exhibits histone H4K20 trimethyltransferase activity (ortholog); histone H4K20me2 reader activity (ortholog); tubulin-tyrosine ligase activity (ortholog); INVOLVED IN negative regulation of type I interferon-mediated signaling pathway (ortholog); regulation of mitotic cell cyc le (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene; alpha-Zearalanol | 7 | 116612609 | 116631244 | Rat | 115 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311255 | Ttll3 | tubulin tyrosine ligase like 3 | ENCODES a protein that exhibits protein-glycine ligase activity (ortholog); protein-glycine ligase activity, initiating (ortholog); INVOLVED IN cilium assembly (ortholog); flagellated sperm motility (ortholog); protein polyglycylation (ortholog); FOUND IN axoneme (ortholog); cilium (ortholog); micro tubule cytoskeleton (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 4 | 148088575 | 148113526 | Rat | 91 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303318 | Tusc3 | tumor suppressor candidate 3 | ENCODES a protein that exhibits oligosaccharyltransferase complex binding (ortholog); INVOLVED IN cognition (ortholog); magnesium ion transport (ortholog); protein N-linked glycosylation (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pa thway; ASSOCIATED WITH autosomal recessive intellectual developmental disorder 24 (ortholog); autosomal recessive intellectual developmental disorder 7 (ortholog); congenital disorder of glycosylation (ortholog); FOUND IN mitochondrion (ortholog); oligosaccharyltransferase complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 16 | 59899642 | 60048813 | Rat | 121 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307538 | Txndc11 | thioredoxin domain containing 11 | FOUND IN cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 10 | 5022464 | 5079958 | Rat | 57 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306755 | Txndc16 | thioredoxin domain containing 16 | FOUND IN endoplasmic reticulum lumen (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 20831541 | 20905661 | Rat | 86 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310386 | Ublcp1 | ubiquitin-like domain containing CTD phosphatase 1 | ENCODES a protein that exhibits proteasome regulatory particle binding (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN negative regulation of ATP-dependent activity (ortholog); regulation of proteasome assembly (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog) ; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | 10 | 29447081 | 29462446 | Rat | 95 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1304745 | Ubtfl1 | upstream binding transcription factor like 1 | ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN blastocyst growth (ortholog); embryo implantation (ortholog); regulation of gene expression (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH benzo[a]pyrene (ortholog); perfluorohexanesulfonic acid (ortho log) | 8 | 23787567 | 23788754 | Rat | 12 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309471 | Ubxn1 | UBX domain protein 1 | ENCODES a protein that exhibits ATPase binding (ortholog); K48-linked polyubiquitin modification-dependent protein binding (ortholog); K6-linked polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN negative regulation of ERAD pathway (ortholog); negative regulation of proteas omal ubiquitin-dependent protein catabolic process (ortholog); negative regulation of protein K48-linked deubiquitination (ortholog); ASSOCIATED WITH Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN dendrite; neuronal cell body; cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 1 | 215194418 | 215198343 | Rat | 112 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307451 | Ubxn4 | UBX domain protein 4 | INVOLVED IN ERAD pathway (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 13 | 42292346 | 42324928 | Rat | 102 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309976 | Unc80 | unc-80 subunit of NALCN channel complex | INVOLVED IN regulation of neuronal action potential (ortholog); sodium ion transmembrane transport (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); brain disease (ortholog); Developmental Disabilities (ortholog); FOUND IN plasma membrane (ortholog); sodium channel complex (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; Cuprizon | 9 | 75461618 | 75639849 | Rat | 82 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1311984 | Unc93b1 | unc-93B1 regulator of TLR signaling | ENCODES a protein that exhibits Toll-like receptor binding (ortholog); INVOLVED IN antigen processing and presentation (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); cell morphogenesis (ortholog); PARTICIPATES IN Toll-like receptor signaling pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Experimental Liver Cirrhosis (ortholog); Herpes Simplex Encephalitis (ortholog); FOUND IN early phagosome (ortholog); endoplasmic reticulum (ortholog); endosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; acetamide | 1 | 210596639 | 210607579 | Rat | 150 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306917 | Uqcc2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | INVOLVED IN mitochondrial respiratory chain complex III assembly (ortholog); positive regulation of mitochondrial translation (ortholog); regulation of insulin secretion (ortholog); ASSOCIATED WITH mitochondrial complex III deficiency nuclear type 1 (ortholog); mitochondrial complex III deficiency n uclear type 7 (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial intermembrane space (ortholog); mitochondrial matrix (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 20 | 5204682 | 5217080 | Rat | 119 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307583 | Uqcc5 | ubiquinol-cytochrome c reductase complex assembly factor 5 | ENCODES a protein that exhibits mitochondrial ribosome binding (ortholog); INVOLVED IN mitochondrial respiratory chain complex III assembly (ortholog); mitochondrial respiratory chain complex IV assembly (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACT S WITH 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil; acrylamide | 16 | 6323071 | 6326911 | Rat | 50 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311825 | Usp14 | ubiquitin specific peptidase 14 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); deubiquitinase activity (ortholog); endopeptidase inhibitor activity (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); inflammatory response (ortholog); negative regulation of ERAD pathway (ortholog); ASSOCIATED WITH distal arthrogryposis (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); cytoplasmic vesicle (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4,6-trinitrotoluene; 2,4-dinitrotoluene | 18 | 1292745 | 1330867 | Rat | 151 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311341 | Utp4 | UTP4 small subunit processome component | INVOLVED IN maturation of SSU-rRNA (ortholog); regulation of DNA-templated transcription (ortholog); ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH cholestasis (ortholog); North American Indian Childhood Cirrhosis (ortholog); primary bilia ry cholangitis (ortholog); FOUND IN chromosome (ortholog); fibrillar center (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 19 | 51696437 | 51730323 | Rat | 88 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311017 | Utp6 | UTP6 small subunit processome component | ENCODES a protein that exhibits snoRNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN chromosome (ortholog); nucleolus (ortholog); small-subunit processome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxi ne; bisphenol A; endosulfan | 10 | 65395253 | 65425928 | Rat | 81 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306371 | Uvssa | UV-stimulated scaffold protein A | ENCODES a protein that exhibits chromatin-protein adaptor activity (ortholog); RNA polymerase II complex binding (ortholog); RNA polymerase inhibitor activity (ortholog); INVOLVED IN protein ubiquitination (ortholog); response to UV (ortholog); transcription-coupled nucleotide-excision repair (ortho log); ASSOCIATED WITH UV-sensitive syndrome (ortholog); UV-Sensitive Syndrome 3 (ortholog); FOUND IN chromosome (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 14 | 81535179 | 81576444 | Rat | 81 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309753 | Vamp4 | vesicle-associated membrane protein 4 | INVOLVED IN neurotransmitter receptor transport, endosome to postsynaptic membrane; regulation of synaptic vesicle endocytosis; synaptic vesicle to endosome fusion; FOUND IN glutamatergic synapse; cell surface (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bi sphenol A | 13 | 77453135 | 77475909 | Rat | 117 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308943 | Vat1 | vesicle amine transport 1 | ENCODES a protein that exhibits NADPH dehydrogenase (quinone) activity (ortholog); phospholipid transfer activity (ortholog); INVOLVED IN intermembrane phospholipid transfer (ortholog); negative regulation of mitochondrial fusion (ortholog); FOUND IN mitochondrial outer membrane; cytoplasm (ortholog ); cytosol (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 10 | 86889793 | 86897411 | Rat | 164 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311653 | Vgll4 | vestigial-like family member 4 | INVOLVED IN negative regulation of cardiac muscle cell proliferation (ortholog); negative regulation of cell growth (ortholog); negative regulation of DNA-templated transcription (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodio xine; amphetamine | 4 | 149598151 | 149711186 | Rat | 121 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305031 | Vta1 | vesicle trafficking 1 | INVOLVED IN multivesicular body sorting pathway (ortholog); PARTICIPATES IN endocytosis pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 1 | 10852966 | 10900764 | Rat | 66 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1311670 | Vwa3a | von Willebrand factor A domain containing 3A | ASSOCIATED WITH urinary bladder cancer (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil; atrazine | 1 | 184725106 | 184786884 | Rat | 41 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308559 | Vwa5b1 | von Willebrand factor A domain containing 5B1 | INTERACTS WITH 1,2-dimethylhydrazine; 6-propyl-2-thiouracil; atrazine | 5 | 156080599 | 156148155 | Rat | 20 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309910 | Vwce | von Willebrand factor C and EGF domains | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cellular response to virus (inferred); ASSOCIATED WITH Dwarfism (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4- dinitrotoluene | 1 | 216703742 | 216753284 | Rat | 94 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308278 | Wars1 | tryptophanyl-tRNA synthetase 1 | ENCODES a protein that exhibits protein domain specific binding (ortholog); protein homodimerization activity (ortholog); protein kinase binding (ortholog); INVOLVED IN intracellular signal transduction (ortholog); regulation of angiogenesis (ortholog); tryptophanyl-tRNA aminoacylation (ortholog); P ARTICIPATES IN tryptophan metabolic pathway; aminoacyl-tRNA biosynthetic pathway; ASSOCIATED WITH autosomal dominant distal hereditary motor neuronopathy 9 (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); protein-containing complex (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 133540463 | 133571645 | Rat | 240 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307299 | Wasf2 | WASP family member 2 | ENCODES a protein that exhibits protein kinase A binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament-based movement (ortholog); ameboidal-type cell migration (ortholog); PARTICIPATES IN E-cadherin signaling pathway; platelet-deriv ed growth factor signaling pathway; Fc gamma receptor mediated signaling pathway; FOUND IN cell-cell junction (ortholog); early endosome (ortholog); lamellipodium (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 5 | 150620733 | 150685943 | Rat | 156 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307097 | Wdfy3 | WD repeat and FYVE domain containing 3 | ENCODES a protein that exhibits 1-phosphatidylinositol binding (ortholog); beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity (ortholog); INVOLVED IN aggrephagy (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal dominant intellectual developmental d isorder 1 (ortholog); esophageal atresia/tracheoesophageal fistula (ortholog); FOUND IN Atg12-Atg5-Atg16 complex (ortholog); autophagosome (ortholog); autophagosome membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 14 | 7873946 | 8115002 | Rat | 146 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304803 | Wdr24 | WD repeat domain 24 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); positive regulation of protein kinase activity (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND I N GATOR2 complex (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,4,6-trinitrotoluene; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 15346835 | 15353384 | Rat | 70 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309633 | Wdr27 | WD repeat domain 27 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); nervous system development (inferred); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; atrazine | 1 | 64505375 | 64623573 | Rat | 54 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309367 | Wdr31 | WD repeat domain 31 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acetamide | 5 | 80914338 | 80933022 | Rat | 53 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308567 | Wdr5b | WD repeat domain 5B | FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 11 | 78216266 | 78218125 | Rat | 51 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306429 | Wdr73 | WD repeat domain 73 | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN cytoplasmic microtubule organization (ortholog); nucleus organization (ortholog); ASSOCIATED WITH dystonia (ortholog); epilepsy (ortholog); Galloway-Mowat syndrome (ortholog); FOUND IN cleavage furrow (ort holog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate | 1 | 144269561 | 144277707 | Rat | 68 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311334 | Wdr81 | WD repeat domain 81 | ENCODES a protein that exhibits K63-linked polyubiquitin modification-dependent protein binding (ortholog); phosphatidylinositol 3-kinase inhibitor activity (ortholog); INVOLVED IN aggrephagy (ortholog); early endosome to late endosome transport (ortholog); mitochondrion organization (ortholog); ASS OCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); cerebellar ataxia (ortholog); cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 2 (ortholog); FOUND IN autophagosome membrane (ortholog); cytosol (ortholog); early endosome membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; allethrin; bisphenol A | 10 | 60780268 | 60793671 | Rat | 130 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359296 | Wdsub1 | WD repeat, sterile alpha motif and U-box domain containing 1 | ENCODES a protein that exhibits ubiquitin-protein transferase activity (inferred); INVOLVED IN protein ubiquitination (inferred); ASSOCIATED WITH autistic disorder (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 3 | 64749118 | 64781525 | Rat | 56 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304986 | Wfdc5 | WAP four-disulfide core domain 5 | ENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH acrylamide; bisphenol A; fenvalerate | 3 | 173268410 | 173274253 | Rat | 32 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303277 | Wfdc6b | WAP four-disulfide core domain 6B | ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Cuprizon | 3 | 173758317 | 173766797 | Rat | 13 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359599 | Wsb2 | WD repeat and SOCS box-containing 2 | INVOLVED IN intracellular signal transduction (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 12 | 44878483 | 44899474 | Rat | 89 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1302980 | Xirp2 | xin actin-binding repeat containing 2 | ENCODES a protein that exhibits actin filament binding (ortholog); alpha-actinin binding (ortholog); INVOLVED IN cardiac muscle tissue morphogenesis (ortholog); cell-cell junction organization (ortholog); positive regulation of protein localization (ortholog); ASSOCIATED WITH blepharophimosis (ortho log); Congenital Heart Defects, Multiple Types, 4 (ortholog); depressive disorder (ortholog); FOUND IN cell-cell junction (ortholog); focal adhesion (ortholog); stress fiber (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acrylamide; alpha-Zearalanol | 3 | 72534175 | 72621056 | Rat | 70 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1312015 | Xpo4 | exportin 4 | ENCODES a protein that exhibits nuclear export signal receptor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN positive regulation of protein export from nucleus (ortholog); protein export from nucleus (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (orthol og); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 15 | 35832567 | 35923262 | Rat | 93 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1306849 | Xrcc3 | X-ray repair cross complementing 3 | ENCODES a protein that exhibits crossover junction DNA endonuclease activity (ortholog); four-way junction DNA binding (ortholog); INVOLVED IN DNA repair (ortholog); double-strand break repair via homologous recombination (ortholog); interstrand cross-link repair (ortholog); PARTICIPATES IN homologo us recombination pathway of double-strand break repair; ASSOCIATED WITH basal cell carcinoma (ortholog); brain glioma (ortholog); breast cancer (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); nuclear replication fork (ortholog); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 6 | 136684558 | 136694822 | Rat | 189 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359573 | Xrcc4 | X-ray repair cross complementing 4 | ENCODES a protein that exhibits 3' overhang single-stranded DNA endodeoxyribonuclease activity (ortholog); DNA binding (ortholog); enzyme binding (ortholog); INVOLVED IN cellular response to lithium ion; base-excision repair (ortholog); central nervous system development (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH Chromosome Aberrations (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN chromosome, telomeric region (ortholog); condensed chromosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; atrazine | 2 | 22686506 | 22932929 | Rat | 209 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308154 | Xxylt1 | xyloside xylosyltransferase 1 | ENCODES a protein that exhibits magnesium ion binding (ortholog); manganese ion binding (ortholog); UDP-xylosyltransferase activity (ortholog); INVOLVED IN protein O-linked glycosylation via glucose (ortholog); protein O-linked glycosylation via N-acetyl-galactosamine (ortholog); ASSOCIATED WITH atr ial fibrillation (ortholog); COVID-19 (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); INTERACTS WITH bisphenol A; dibutyl phthalate; sodium arsenite | 11 | 83163432 | 83295879 | Rat | 65 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1308722 | Ybey | ybeY metalloendoribonuclease | ENCODES a protein that exhibits RNA endonuclease activity (ortholog); INVOLVED IN rRNA processing (inferred); FOUND IN mitochondrion (ortholog); nucleus (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; alpha-Zearalanol; bisphenol A | 20 | 12164678 | 12175150 | Rat | 61 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359227 | Ydjc | YdjC chitooligosaccharide deacetylase homolog | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN carbohydrate metabolic process (inferred); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol | 11 | 97338529 | 97348909 | Rat | 63 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305741 | Yeats4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (ortholog); histone H3K27ac reader activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma; liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acrylamide | 7 | 54744220 | 54751361 | Rat | 83 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308632 | Zbbx | zinc finger, B-box domain containing | ENCODES a protein that exhibits zinc ion binding (inferred); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; aflatoxin B1 (ortholog) | 2 | 162134252 | 162245538 | Rat | 26 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307122 | Zc2hc1c | zinc finger, C2HC-type containing 1C | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 6 | 110663682 | 110672606 | Rat | 44 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303257 | Zc3h18 | zinc finger CCCH-type containing 18 | ENCODES a protein that exhibits mRNA cap binding complex binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN RNA destabilization (ortholog); FOUND IN nuclear speck (ortholog); protein-containing complex (ortholog); ribonucleoprotein complex (ortholog); INTERACTS WITH 2 ,4-dinitrotoluene; 2,6-dinitrotoluene; atrazine | 19 | 67344422 | 67388400 | Rat | 74 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307276 | Zc3h3 | zinc finger CCCH type containing 3 | ENCODES a protein that exhibits R-SMAD binding (ortholog); SMAD binding (ortholog); INVOLVED IN mRNA 3'-end processing (ortholog); positive regulation of activin receptor signaling pathway (ortholog); ASSOCIATED WITH lymphopenia (ortholog); neutropenia (ortholog); FOUND IN mRNA cleavage and polyaden ylation specificity factor complex (ortholog); nucleus (ortholog); INTERACTS WITH amitrole; bisphenol A; gentamycin | 7 | 109321423 | 109406241 | Rat | 76 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309236 | Zc3hav1l | ZC3HAV1 like | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; amphetamine | 4 | 67957250 | 67972540 | Rat | 68 | PANTHER | gene, protein-coding, MODEL [RefSeq] |
| 1310467 | Zcchc7 | zinc finger CCHC-type containing 7 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); zinc ion binding (inferred); PARTICIPATES IN RNA degradation pathway; FOUND IN cytosol (ortholog); nucleolus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachl orodibenzofuran | 5 | 63787292 | 63968960 | Rat | 127 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307450 | Zcchc9 | zinc finger CCHC-type containing 9 | ENCODES a protein that exhibits nucleic acid binding (inferred); zinc ion binding (inferred); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; flutamide | 2 | 24773319 | 24783339 | Rat | 60 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309851 | Zcrb1 | zinc finger CCHC-type and RNA binding motif containing 1 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); RNA splicing (inferred); FOUND IN U12-type spliceosomal complex (ortholog); INTERACTS WITH 2,3,7,8 -Tetrachlorodibenzofuran; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 7 | 126404675 | 126418012 | Rat | 53 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308875 | Zdhhc8 | zDHHC palmitoyltransferase 8 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN locomotory behavior (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN glutamatergic synapse (ort holog); Golgi apparatus (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 11 | 96259383 | 96273588 | Rat | 64 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1359259 | Zfp219 | zinc finger protein 219 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN limb bud formation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 15 | 27169335 | 27183555 | Rat | 124 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307510 | Zfp330 | zinc finger protein 330 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); FOUND IN chromosome, centromeric region (ortholog); midbody (ortholog); nucleolus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; cobalt dichloride | 19 | 42218213 | 42229516 | Rat | 77 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308705 | Zfp592 | zinc finger protein 592 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); ASSOCIATED WITH bipolar disorder (ortholog); Galloway-Mowat syndrome (ortholog); Galloway-Mowat syndrome 1 (ortholog); FOUND IN nucle us (inferred); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; amitrole | 1 | 144355227 | 144411686 | Rat | 69 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310179 | Zfp593 | zinc finger protein 593 | ENCODES a protein that exhibits preribosome binding (ortholog); zinc ion binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ort holog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 5 | 151746396 | 151748724 | Rat | 85 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307820 | Zfyve26 | zinc finger FYVE-type containing 26 | ENCODES a protein that exhibits phosphatidylinositol-3-phosphate binding (ortholog); protein kinase binding (ortholog); INVOLVED IN autophagosome organization (ortholog); double-strand break repair via homologous recombination (ortholog); lysosome organization (ortholog); ASSOCIATED WITH fundus dyst rophy (ortholog); genetic disease (ortholog); hereditary spastic paraplegia (ortholog); FOUND IN centrosome (ortholog); early endosome (ortholog); late endosome (ortholog); INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; copper atom | 6 | 103764864 | 103828520 | Rat | 121 | PANTHER | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310801 | Zgpat | zinc finger CCCH-type and G-patch domain containing | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-template d transcription (ortholog); negative regulation of epidermal growth factor-activated receptor activity (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH neuronal ceroid lipofuscinosis (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; amitrole | 3 | 188851376 | 188867914 | Rat | 90 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1305834 | Zgrf1 | zinc finger, GRF-type containing 1 | ENCODES a protein that exhibits 5'-3' DNA helicase activity (ortholog); INVOLVED IN recombinational repair (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); speech-language disorder-1 (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH acrylamide; aflatoxin B1; bisphenol A | 2 | 218687413 | 218750104 | Rat | 73 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1303252 | Zmynd11 | zinc finger, MYND-type containing 11 | ENCODES a protein that exhibits double-stranded DNA binding (ortholog); histone H3K36me3 reader activity (ortholog); transcription corepressor activity (ortholog); INVOLVED IN defense response to virus (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); negative re gulation of extrinsic apoptotic signaling pathway (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal dominant intellectual developmental disorder 1 (ortholog); autosomal dominant intellectual developmental disorder 30 (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; clofibric acid | 17 | 65226907 | 65323278 | Rat | 122 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1307175 | Zmynd12 | zinc finger, MYND-type containing 12 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN flagellated sperm motility (ortholog); sperm axoneme assembly (ortholog); FOUND IN sperm flagellum (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodiben zodioxine | 5 | 138312257 | 138345269 | Rat | 63 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309845 | Zmynd15 | zinc finger, MYND-type containing 15 | ENCODES a protein that exhibits histone deacetylase binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); spermatid development (ortholog); ASSOCIATED WITH male infertility (ortholog); spermatogenic failure 14 (ortholog); spermatogenic failure 3 (ortholog); F OUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 10 | 55669832 | 55676446 | Rat | 86 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310324 | Zswim7 | zinc finger, SWIM-type containing 7 | ENCODES a protein that exhibits zinc ion binding (inferred); INVOLVED IN double-strand break repair via homologous recombination (ortholog); protein stabilization (ortholog); ASSOCIATED WITH infertility (ortholog); ovarian dysgenesis 10 (ortholog); spermatogenic failure 3 (ortholog); FOUND IN Shu co mplex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 10 | 47456843 | 47469084 | Rat | 51 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1309414 | Zswim8 | zinc finger, SWIM-type containing 8 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN positive regulation of miRNA catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); protein quality control for misfolded or incompletely synt hesized proteins (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); cullin-RING ubiquitin ligase complex (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 4,4'-sulfonyldiphenol; bisphenol A | 15 | 3623040 | 3638748 | Rat | 72 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |
| 1310257 | Zswim9 | zinc finger SWIM-type containing 9 | ENCODES a protein that exhibits zinc ion binding (inferred); INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); INTERACTS WITH bisphenol A; thioacetamide; 3-isobutyl-1-methyl-7H-xanthine (ortholog) | 1 | 83222133 | 83243116 | Rat | 23 | PANTHER | gene, protein-coding, VALIDATED [RefSeq] |