Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of ARGLU1 mRNA | CTD | PMID:24763279 | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ARGLU1 mRNA] | CTD | PMID:31150632 | (-)-demecolcine | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Demecolcine results in decreased expression of ARGLU1 mRNA | CTD | PMID:23649840 | (1->4)-beta-D-glucan | multiple interactions | ISO | Arglu1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ARGLU1 mRNA | CTD | PMID:36331819 | (S)-nicotine | increases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Nicotine results in increased expression of ARGLU1 mRNA | CTD | PMID:16949557 | 1,2-dimethylhydrazine | multiple interactions | ISO | Arglu1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of ARGLU1 mRNA] | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Arglu1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARGLU1 promoter] | CTD | PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ARGLU1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARGLU1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Arglu1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARGLU1 mRNA | CTD | PMID:21570461 and PMID:24680724 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Arglu1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of ARGLU1 mRNA | CTD | PMID:20188158 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ARGLU1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ARGLU1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ARGLU1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ARGLU1 mRNA | CTD | PMID:36041667 | 4-hydroxyphenyl retinamide | increases expression | ISO | Arglu1 (Mus musculus) | 6480464 | Fenretinide results in increased expression of ARGLU1 mRNA | CTD | PMID:28973697 | aflatoxin B1 | decreases methylation | ISO | ARGLU1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ARGLU1 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ARGLU1 mRNA | CTD | PMID:21934132 | benzo[a]pyrene | increases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of ARGLU1 mRNA | CTD | PMID:26238291 | benzo[a]pyrene | multiple interactions | ISO | Arglu1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ARGLU1 mRNA | CTD | PMID:27858113 | benzo[b]fluoranthene | multiple interactions | ISO | Arglu1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ARGLU1 mRNA | CTD | PMID:27858113 | Benzo[ghi]perylene | decreases expression | ISO | Arglu1 (Mus musculus) | 6480464 | 1 and 12-benzoperylene results in decreased expression of ARGLU1 mRNA | CTD | PMID:26377693 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ARGLU1 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ARGLU1 mRNA | CTD | PMID:36041667 | bisphenol A | increases methylation | ISO | ARGLU1 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of ARGLU1 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ARGLU1 mRNA | CTD | PMID:33670352 | bisphenol A | decreases expression | ISO | Arglu1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ARGLU1 mRNA | CTD | PMID:32156529 and PMID:33221593 | bisphenol A | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ARGLU1 mRNA | CTD | PMID:28628672 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ARGLU1 mRNA | CTD | PMID:36041667 | cadmium atom | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ARGLU1 mRNA | CTD | PMID:35301059 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of ARGLU1 mRNA | CTD | PMID:19010381 | cadmium dichloride | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ARGLU1 mRNA | CTD | PMID:35301059 | caffeine | decreases phosphorylation | ISO | ARGLU1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of ARGLU1 protein | CTD | PMID:35688186 | cannabidiol | increases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Cannabidiol results in increased expression of ARGLU1 mRNA | CTD | PMID:27918106 | carbon nanotube | decreases expression | ISO | Arglu1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | carbon nanotube | increases expression | ISO | Arglu1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of ARGLU1 mRNA | CTD | PMID:25620056 | chrysene | multiple interactions | ISO | Arglu1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ARGLU1 mRNA | CTD | PMID:27858113 | coumarin | decreases phosphorylation | ISO | ARGLU1 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of ARGLU1 protein | CTD | PMID:35688186 | cyclosporin A | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ARGLU1 mRNA | CTD | PMID:25562108 | deoxynivalenol | decreases phosphorylation | ISO | Arglu1 (Mus musculus) | 6480464 | deoxynivalenol results in decreased phosphorylation of ARGLU1 protein | CTD | PMID:23811945 | dexamethasone | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ARGLU1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ARGLU1 mRNA | CTD | PMID:28628672 | dibenz[a,h]anthracene | decreases expression | ISO | Arglu1 (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:26377693 | diethylstilbestrol | increases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Diethylstilbestrol results in increased expression of ARGLU1 mRNA | CTD | PMID:36621641 | dorsomorphin | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | folic acid | multiple interactions | ISO | Arglu1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of ARGLU1 mRNA] | CTD | PMID:22206623 | FR900359 | affects phosphorylation | ISO | ARGLU1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of ARGLU1 protein | CTD | PMID:37730182 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of ARGLU1 gene | CTD | PMID:22079235 | indometacin | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ARGLU1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ARGLU1 mRNA | CTD | PMID:28628672 | lead diacetate | increases expression | ISO | Arglu1 (Mus musculus) | 6480464 | lead acetate results in increased expression of ARGLU1 mRNA | CTD | PMID:21829687 | leflunomide | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of ARGLU1 mRNA | CTD | PMID:28988120 | methotrexate | increases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of ARGLU1 mRNA | CTD | PMID:24449571 | methylmercury chloride | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of ARGLU1 mRNA | CTD | PMID:28001369 | mono(2-ethyl-5-oxohexyl) phthalate | affects expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | mono(2-ethyl-5-oxohexyl)phthalate affects the expression of ARGLU1 mRNA | CTD | PMID:34478338 | nicotine | increases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Nicotine results in increased expression of ARGLU1 mRNA | CTD | PMID:16949557 | ozone | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of ARGLU1 mRNA | CTD | PMID:35430440 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Arglu1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ARGLU1 mRNA | CTD | PMID:36331819 | SB 431542 | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | sodium arsenate | increases expression | ISO | Arglu1 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of ARGLU1 mRNA | CTD | PMID:21795629 | sodium arsenite | increases expression | ISO | Arglu1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of ARGLU1 mRNA | CTD | PMID:36209798 | sulindac | increases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Sulindac results in increased expression of ARGLU1 mRNA | CTD | PMID:11906190 | sunitinib | increases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of ARGLU1 mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of ARGLU1 mRNA | CTD | PMID:31758290 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ARGLU1 mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of ARGLU1 mRNA | CTD | PMID:31150632 | tetraphene | decreases expression | ISO | Arglu1 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of ARGLU1 mRNA | CTD | PMID:26377693 | tetraphene | multiple interactions | ISO | Arglu1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ARGLU1 mRNA | CTD | PMID:27858113 | thimerosal | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of ARGLU1 mRNA | CTD | PMID:27188386 | titanium dioxide | increases expression | ISO | Arglu1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of ARGLU1 mRNA | CTD | PMID:29264374 | topotecan | affects response to substance | ISO | ARGLU1 (Homo sapiens) | 6480464 | ARGLU1 protein affects the susceptibility to Topotecan | CTD | PMID:16217747 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of ARGLU1 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of ARGLU1 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARGLU1 mRNA | CTD | PMID:27188386 | Triptolide | increases expression | EXP | | 6480464 | triptolide results in increased expression of ARGLU1 protein | CTD | PMID:32519852 | urethane | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of ARGLU1 mRNA | CTD | PMID:28818685 | valproic acid | decreases methylation | ISO | ARGLU1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of ARGLU1 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ARGLU1 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | ARGLU1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARGLU1 mRNA | CTD | PMID:27188386 | vorinostat | decreases expression | ISO | ARGLU1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of ARGLU1 mRNA | CTD | PMID:27188386 | |