Mymx (myomixer, myoblast fusion factor) - Rat Genome Database

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Gene: Mymx (myomixer, myoblast fusion factor) Rattus norvegicus
Analyze
Symbol: Mymx
Name: myomixer, myoblast fusion factor
RGD ID: 11426996
Description: Predicted to be involved in myoblast fusion involved in skeletal muscle regeneration; plasma membrane fusion; and skeletal muscle organ development. Predicted to be located in Golgi membrane; endoplasmic reticulum membrane; and plasma membrane. Human ortholog(s) of this gene implicated in Carey-Fineman-Ziter syndrome. Orthologous to human MYMX (myomixer, myoblast fusion factor); INTERACTS WITH 1,4-dichlorobenzene (ortholog); chlorpyrifos (ortholog); triptonide (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC108352018; uncharacterized LOC101929726 homolog; uncharacterized LOC108352018
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8922,894,524 - 22,895,701 (+)NCBIGRCr8
mRatBN7.2915,397,086 - 15,398,263 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl915,397,144 - 15,398,263 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx923,983,681 - 23,984,858 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0929,046,358 - 29,047,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0927,347,118 - 27,348,295 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,781,397 - 17,783,074 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,782,395 - 17,782,664 (+)EnsemblRnor6.0rn6Rnor6.0
Celera913,140,601 - 13,142,278 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
Additional References at PubMed
PMID:28386024   PMID:28569745   PMID:28569755   PMID:29581287   PMID:30197239  


Genomics

Comparative Map Data
Mymx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8922,894,524 - 22,895,701 (+)NCBIGRCr8
mRatBN7.2915,397,086 - 15,398,263 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl915,397,144 - 15,398,263 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx923,983,681 - 23,984,858 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0929,046,358 - 29,047,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0927,347,118 - 27,348,295 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,781,397 - 17,783,074 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,782,395 - 17,782,664 (+)EnsemblRnor6.0rn6Rnor6.0
Celera913,140,601 - 13,142,278 (+)NCBICelera
Cytogenetic Map9q12NCBI
MYMX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38644,192,721 - 44,218,234 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl644,216,926 - 44,218,234 (+)EnsemblGRCh38hg38GRCh38
GRCh37644,184,663 - 44,185,971 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map6p21.1NCBI
HuRef643,906,811 - 43,908,115 (+)NCBIHuRef
CHM1_1644,188,410 - 44,189,713 (+)NCBICHM1_1
T2T-CHM13v2.0644,051,103 - 44,052,410 (+)NCBIT2T-CHM13v2.0
Mymx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391745,911,887 - 45,913,122 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1745,911,897 - 45,913,028 (-)EnsemblGRCm39 Ensembl
GRCm381745,600,961 - 45,602,196 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,600,971 - 45,602,102 (-)EnsemblGRCm38mm10GRCm38
MGSCv371745,737,916 - 45,739,051 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361745,064,552 - 45,065,496 (-)NCBIMGSCv36mm8
MGSCv361744,621,222 - 44,622,166 (-)NCBIMGSCv36mm8
Cytogenetic Map17CNCBI
cM Map1722.59NCBI
MYMX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,719,590 - 58,722,520 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,589,673 - 54,592,605 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,812,606 - 43,814,252 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1645,096,551 - 45,097,878 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl645,097,114 - 45,097,368 (+)Ensemblpanpan1.1panPan2
MYMX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,626,482 - 12,630,058 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,651,891 - 12,655,481 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01213,108,904 - 13,112,493 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1213,111,742 - 13,111,996 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,634,365 - 12,637,954 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,722,315 - 12,725,907 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,816,043 - 12,819,633 (+)NCBIUU_Cfam_GSD_1.0
Mymx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494648,095,049 - 48,096,795 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647615,863,807 - 15,864,161 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647615,863,807 - 15,864,357 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110261530
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl739,216,513 - 39,216,779 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1739,215,933 - 39,217,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MYMX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366604444,270,375 - 44,271,682 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mymx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475415,637,322 - 15,637,883 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mymx
10 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:46
Interacting mature miRNAs:50
Transcripts:ENSRNOT00000064497
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 10 14 14 14 3 5 6 14 17 4 3
Below cutoff 4 4 2 1 2 2 3 8 9 11 3 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000064497   ⟹   ENSRNOP00000059387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl915,397,144 - 15,398,263 (+)Ensembl
Rnor_6.0 Ensembl917,782,395 - 17,782,664 (+)Ensembl
RefSeq Acc Id: NM_001399465   ⟹   NP_001386394
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8922,894,655 - 22,895,701 (+)NCBI
mRatBN7.2915,397,217 - 15,398,263 (+)NCBI
RefSeq Acc Id: NM_001399466   ⟹   NP_001386395
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8922,894,624 - 22,895,701 (+)NCBI
mRatBN7.2915,397,186 - 15,398,263 (+)NCBI
RefSeq Acc Id: NM_001399467   ⟹   NP_001386396
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8922,894,524 - 22,895,701 (+)NCBI
mRatBN7.2915,397,086 - 15,398,263 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001386394 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386395 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386396 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000059387
  ENSRNOP00000059387.3
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000059387   ⟸   ENSRNOT00000064497
RefSeq Acc Id: NP_001386396   ⟸   NM_001399467
- Peptide Label: precursor
- UniProtKB: D4A557 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386395   ⟸   NM_001399466
- Peptide Label: precursor
- UniProtKB: D4A557 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386394   ⟸   NM_001399465
- Peptide Label: precursor
- UniProtKB: D4A557 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A557-F1-model_v2 AlphaFold D4A557 1-89 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:11426996 AgrOrtholog
BioCyc Gene G2FUF-28177 BioCyc
Ensembl Genes ENSRNOG00000042497 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064497 ENTREZGENE
  ENSRNOT00000064497.3 UniProtKB/TrEMBL
InterPro Myomixer UniProtKB/TrEMBL
KEGG Report rno:108352018 UniProtKB/TrEMBL
NCBI Gene LOC108352018 ENTREZGENE
PANTHER PROTEIN MYOMIXER UniProtKB/TrEMBL
  PTHR41686 UniProtKB/TrEMBL
PhenoGen Mymx PhenoGen
RatGTEx ENSRNOG00000042497 RatGTEx
UniProt D4A557 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-09-05 Mymx  myomixer, myoblast fusion factor  LOC108352018  uncharacterized LOC108352018  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-08-02 LOC108352018  uncharacterized LOC108352018      Symbol and Name status set to provisional 70820 PROVISIONAL