Tesl (testis derived transcript-like) - Rat Genome Database

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Gene: Tesl (testis derived transcript-like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Tesl
Name: testis derived transcript-like
RGD ID: 1305365
Description: Predicted to enable zinc ion binding activity. Predicted to be located in cytoplasm and focal adhesion. Orthologous to human TES (testin LIM domain protein); INTERACTS WITH bisphenol A; rotenone; trichloroethene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC316142; Tes; testis derived transcript
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X119,485,153 - 119,498,721 (-)NCBIGRCr8
mRatBN7.2X114,680,227 - 114,693,795 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX114,680,227 - 114,693,808 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX116,711,725 - 116,725,292 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X120,202,992 - 120,216,559 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X117,756,593 - 117,770,160 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X121,053,287 - 121,066,855 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX121,053,297 - 121,066,855 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X121,200,296 - 121,213,864 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X9,556,982 - 9,570,550 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X9,562,538 - 9,576,004 (+)NCBI
CeleraX113,867,642 - 113,881,010 (-)NCBICelera
Cytogenetic MapXq34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Variants

.
Variants in Tesl
64 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:57
Count of miRNA genes:49
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000044165
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX112934952138400867Rat
5685004Bss104Bone structure and strength QTL 1043.9tibia area (VT:1000281)tibia area measurement (CMO:0001382)X113805422126975220Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system integumental system musculoskeletal system nervous system reproductive system appendage
High
Medium 7
Low
Below cutoff 1 1 1 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000044165   ⟹   ENSRNOP00000050413
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX114,680,227 - 114,693,808 (-)Ensembl
Rnor_6.0 EnsemblX121,053,297 - 121,066,855 (-)Ensembl
RefSeq Acc Id: NM_001113750   ⟹   NP_001107222
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X119,485,153 - 119,498,721 (-)NCBI
mRatBN7.2X114,680,227 - 114,693,795 (-)NCBI
Rnor_6.0X121,053,287 - 121,066,855 (-)NCBI
Rnor_5.0X121,200,296 - 121,213,864 (-)NCBI
RGSC_v3.4X9,556,982 - 9,570,550 (+)RGD
CeleraX113,867,642 - 113,881,010 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001107222 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58596 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000050413
  ENSRNOP00000050413.2
Reference Protein Sequences
RefSeq Acc Id: NP_001107222   ⟸   NM_001113750
- UniProtKB: B0BMX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000050413   ⟸   ENSRNOT00000044165
Protein Domains
LIM zinc-binding   PET

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BMX0-F1-model_v2 AlphaFold B0BMX0 1-406 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305365 AgrOrtholog
BioCyc Gene G2FUF-1338 BioCyc
Ensembl Genes ENSRNOG00000033628 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044165 ENTREZGENE
  ENSRNOT00000044165.3 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7111579 IMAGE-MGC_LOAD
InterPro LIM1_Testin UniProtKB/TrEMBL
  LIM2_Testin UniProtKB/TrEMBL
  PET_domain UniProtKB/TrEMBL
  PET_testin UniProtKB/TrEMBL
  Pk/Esn/Tes UniProtKB/TrEMBL
  Znf_LIM UniProtKB/TrEMBL
KEGG Report rno:316142 UniProtKB/TrEMBL
MGC_CLONE MGC:187428 IMAGE-MGC_LOAD
NCBI Gene 316142 ENTREZGENE
PANTHER LIM DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  PTHR24211:SF1 UniProtKB/TrEMBL
Pfam LIM UniProtKB/TrEMBL
  PET UniProtKB/TrEMBL
PhenoGen Tesl PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
  PET UniProtKB/TrEMBL
RatGTEx ENSRNOG00000033628 RatGTEx
SMART LIM UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt B0BMX0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-05-05 Tesl  testis derived transcript-like  Tes_predicted  testis derived transcript (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Tes_predicted  testis derived transcript (predicted)      Symbol and Name status set to approved 70820 APPROVED