Fuz (fuzzy planar cell polarity protein)

Gene: Fuz (fuzzy planar cell polarity protein) Rattus norvegicus

Analyze

Symbol:

Fuz

Name:

fuzzy planar cell polarity protein

RGD ID:

1310608

Description:

Predicted to be involved in several processes, including embryonic morphogenesis; non-motile cilium assembly; and regulation of signal transduction. Predicted to act upstream of or within several processes, including circulatory system development; embryonic morphogenesis; and regionalization. Predicted to be located in cell projection; cytoplasm; and cytoskeleton. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human FUZ (fuzzy planar cell polarity protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

fuzzy homolog (Drosophila); LOC308577; MGC125220; protein fuzzy homolog; RGD1310608; similar to hypothetical protein FLJ22688

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FUZ (fuzzy planar cell polarity protein)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Fuz (fuzzy planar cell polarity protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Fuz (fuzzy planar cell polarity protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FUZ (fuzzy planar cell polarity protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FUZ (fuzzy planar cell polarity protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fuz (fuzzy planar cell polarity protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FUZ (fuzzy planar cell polarity protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FUZ (fuzzy planar cell polarity protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Fuz (fuzzy planar cell polarity protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	HOXB8 (homeobox B8)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Fuz (fuzzy planar cell polarity protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	FUZ (fuzzy planar cell polarity protein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fuz (fuzzy planar cell polarity protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	fy	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	fuz	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,515,782 - 104,524,591 (+)	NCBI		GRCr8
mRatBN7.2	1	95,379,542 - 95,384,532 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,379,587 - 95,384,530 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	100,764,983 - 100,769,925 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	109,237,648 - 109,242,590 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,528,041 - 102,532,983 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	100,891,832 - 100,896,811 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,891,866 - 100,896,807 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	101,956,459 - 101,961,429 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,368,416 - 95,373,967 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	95,446,539 - 95,451,301 (+)	NCBI
Celera	1	89,641,309 - 89,646,323 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asphyxiating thoracic dystrophy (ISO)

developmental and epileptic encephalopathy 12 (ISO)

genetic disease (ISO)

neural tube defect (ISO)

short-rib thoracic dysplasia 6 with or without polydactyly (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-methylcholine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

amiodarone (ISO)

amitrole (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

dexamethasone (ISO)

folic acid (ISO)

indometacin (ISO)

L-methionine (ISO)

methamphetamine (ISO)

methimazole (EXP)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

sodium arsenite (ISO)

tetrachloroethene (ISO)

tetrachloromethane (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anterior/posterior pattern specification (ISO)

aorta development (ISO)

cardiac septum development (ISO)

cilium assembly (ISO,ISS)

coronary vasculature development (ISO)

embryonic body morphogenesis (ISO,ISS)

embryonic digit morphogenesis (ISO)

embryonic neurocranium morphogenesis (ISO)

embryonic skeletal system morphogenesis (ISO,ISS)

establishment of planar polarity (ISO,ISS)

hair follicle development (ISO,ISS)

larynx morphogenesis (ISO)

negative regulation of canonical Wnt signaling pathway (ISO,ISS)

negative regulation of cell migration (ISO,ISS)

negative regulation of cell population proliferation (ISO,ISS)

negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation (ISO,ISS)

negative regulation of neural crest formation (ISO,ISS)

neural tube closure (ISO,ISS)

non-motile cilium assembly (IBA,IEA,ISO,ISS)

positive regulation of cilium assembly (ISO,ISS)

positive regulation of protein processing (ISO)

protein transport (IEA)

regulation of smoothened signaling pathway (ISO,ISS)

roof of mouth development (ISO)

spinal cord development (ISO)

spinal cord dorsal/ventral patterning (ISO)

tongue morphogenesis (ISO)

vesicle-mediated transport (IEA)

Cellular Component

cell projection (IEA)

cytoplasm (IEA)

cytoskeleton (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:19056867	PMID:19767740	PMID:19877275	PMID:20962855	PMID:21761479	PMID:21840926	PMID:21935430	PMID:23806618	PMID:25807483	PMID:27158779	PMID:27395007
PMID:28177282

Genomics

Comparative Map Data

Fuz
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,515,782 - 104,524,591 (+)	NCBI		GRCr8
mRatBN7.2	1	95,379,542 - 95,384,532 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,379,587 - 95,384,530 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	100,764,983 - 100,769,925 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	109,237,648 - 109,242,590 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,528,041 - 102,532,983 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	100,891,832 - 100,896,811 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,891,866 - 100,896,807 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	101,956,459 - 101,961,429 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,368,416 - 95,373,967 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	95,446,539 - 95,451,301 (+)	NCBI
Celera	1	89,641,309 - 89,646,323 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

FUZ
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	49,806,866 - 49,813,553 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	49,806,866 - 49,817,376 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	50,310,123 - 50,316,549 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	55,001,961 - 55,008,280 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	47,179,576 - 47,186,020 (-)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	46,686,436 - 46,692,879 (-)	NCBI		HuRef
CHM1_1	19	50,311,942 - 50,318,409 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	52,807,004 - 52,813,691 (-)	NCBI		T2T-CHM13v2.0

Fuz
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,545,517 - 44,552,053 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,545,503 - 44,552,055 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	44,894,305 - 44,900,624 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	44,896,079 - 44,902,631 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	52,151,449 - 52,155,994 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	44,766,647 - 44,768,389 (+)	NCBI		MGSCv36	mm8
Celera	7	40,346,281 - 40,350,826 (+)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	28.99	NCBI

Fuz
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,112,855 - 1,117,413 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,112,670 - 1,117,620 (+)	NCBI	ChiLan1.0	ChiLan1.0

FUZ
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	55,922,445 - 55,928,900 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	57,843,455 - 57,849,635 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	46,819,833 - 46,826,235 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	55,736,325 - 55,742,589 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	55,736,325 - 55,742,589 (-)	Ensembl	panpan1.1		panPan2

FUZ
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	106,742,381 - 106,752,543 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	106,747,860 - 106,805,699 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	106,330,638 - 106,335,786 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	107,268,672 - 107,273,819 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	107,268,737 - 107,273,513 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	106,940,734 - 106,945,881 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	106,582,739 - 106,587,885 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	107,423,205 - 107,428,353 (+)	NCBI		UU_Cfam_GSD_1.0

Fuz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,978,574 - 21,983,480 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	3,596,952 - 3,601,342 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	3,596,764 - 3,601,676 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FUZ
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	54,823,668 - 54,829,506 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	54,823,680 - 54,830,425 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	50,552,812 - 50,559,474 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FUZ
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	42,968,715 - 42,975,374 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	42,969,000 - 42,975,368 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	22,943,449 - 22,949,774 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fuz
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	4,509,505 - 4,514,183 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	4,509,118 - 4,514,180 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Fuz
12 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	178
Count of miRNA genes:	67
Interacting mature miRNAs:	72
Transcripts:	ENSRNOT00000027701, ENSRNOT00000056331
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	56732668	98773277	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	56949932	101949932	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	65789093	115540829	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	66023617	118608521	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	77494165	122494165	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	77857876	122857876	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	77876254	106047988	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	78350581	123350581	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	78430536	123430536	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	78479925	123479925	Rat
4889494	Scort2	Serum corticosterone level QTL 2	4.2		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	80592172	125592172	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	82174743	118944897	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)	1	83547917	128547917	Rat
2300324	Fetw1	Fetal weight QTL 1	12.1	0.005	fetal growth trait (VT:0004201)	fetal body weight (CMO:0002080)	1	85424647	100358001	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	87580395	150700247	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	90508614	173018436	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	90532338	123479925	Rat
1300153	Bp171	Blood pressure QTL 171	3.37		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	90664883	143200202	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	92184926	137184926	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	92948896	144267916	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	94494440	117601394	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94494440	172949803	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat

Markers in Region

Ap2a1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	95,384,325 - 95,384,502 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,896,605 - 100,896,781	NCBI	Rnor6.0
Rnor_5.0	1	101,961,224 - 101,961,399	UniSTS	Rnor5.0
RGSC_v3.4	1	95,373,155 - 95,373,937	UniSTS	RGSC3.4
Celera	1	89,646,048 - 89,646,293	UniSTS
Cytogenetic Map	1	q22	UniSTS

AW530045

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	95,384,078 - 95,384,282 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,896,358 - 100,896,561	NCBI	Rnor6.0
Rnor_5.0	1	101,960,977 - 101,961,180	UniSTS	Rnor5.0
RGSC_v3.4	1	95,372,908 - 95,373,111	UniSTS	RGSC3.4
Celera	1	89,645,801 - 89,646,004	UniSTS
RH 3.4 Map	1	908.59	UniSTS
Cytogenetic Map	1	q22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium					1		2	4	73	19	28	6	2
Low	3	43	57	41	18	41	6	7	1	16	13	5	6
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001037646	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399381	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759374	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261942	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_590150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094894	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC107809	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228777	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000083336 ⟹ ENSRNOP00000070688

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	95,379,602 - 95,384,309 (+)	Ensembl
Rnor_6.0 Ensembl	1	100,892,006 - 100,896,550 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000086890 ⟹ ENSRNOP00000074982

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	95,379,587 - 95,384,530 (+)	Ensembl
Rnor_6.0 Ensembl	1	100,891,866 - 100,896,807 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000093831 ⟹ ENSRNOP00000076641

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	95,379,602 - 95,384,309 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000114637 ⟹ ENSRNOP00000091471

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	95,379,607 - 95,384,301 (+)	Ensembl

RefSeq Acc Id:

NM_001037646 ⟹ NP_001032735

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,516,076 - 104,521,018 (+)	NCBI
mRatBN7.2	1	95,379,590 - 95,384,532 (+)	NCBI
Rnor_6.0	1	100,891,866 - 100,896,811 (+)	NCBI
Rnor_5.0	1	101,956,459 - 101,961,429 (+)	NCBI
RGSC_v3.4	1	95,368,416 - 95,373,967 (+)	RGD
Celera	1	89,641,309 - 89,646,323 (+)	RGD

Sequence:

show sequence

CCAGTTGGAGGGGCTGAATTGATGATCCCGCTTCTCGCCCTTTGGCGGCTCCAAACAGCAGGCC
ACTTTGCCTACCCGCATGCTCCCAGATCCACACCGAGAGTCTCCAGGGGCGTGACTTTCCGGGT
GCGGGCTTCGAGATGGGGGATGACGGGCCAGGAAGCACGGTGCATCTGCTGTGCCTCGCAGCCT
CTAGCGGGGTTCCCCTGTTCTGTCGGAGCAGCAGCGGAGGCGCCCCCTCCCGTCAACAGCTCCC
TTTTTCTGTCATCGGGTCCCTCAATGGAGTCCACATGTTCGGCCAGAATCTGGATGTGCAACTG
AACTCCGCAAGAACAGAAGACACCACCGTAGTGTGGAAGAACTTCCATGACAGCATCACCCTCA
TTGCTCTGTCATCTGAGGAGGGCACCTCTGAGCTGAAGCTGGAAAGAATGCTCCACATGGTGTT
TGGGGCCATGGTTCTCATTGTGGGACTTGAGGAGCTGACCAATATCCGGAATGTAGAGAGACTG
AAGAAAGAGCTGAGGGCCAGCTACTGTCTCATTGACAGCTTCCTGGGGAATTCAGAGCTCATCG
GGGACCTGACCCAGTGTGTGGACTGTGTCATTCCTCCAGAGGGGTCTGTCATGCAGGTCCCCCA
TCGGTTGTTGACCTTGACTCTGCTGCGGGGCCTGGAGCTGTGTCTGCTCTGCGGGCCGCGCCCG
CCCCTCGGTGAGCTGGACCCACAGTTGCTGGAACGCTGGTGGCAGCCTCTGCTGGAGCCCCTCC
GGGCTTGCCTGCCACTGGGCCCTAGGGCGCTCCCTGACGGGTTCCCGCTACACAGCGATATTCT
TGGCCTGTTGTTACTCCACTTGGAACTGAGACGCTGCCTCTTTACCGTGGAGCCCTCAAAGGAT
AAAGAGCCTTCCCCTGAGCAACGCAGGCGCCTCCTTAGAAATTTCTATACGTTGGTGGCCACCA
CCCACTTCCCACCAGAACCGGGGCCAGCAGAGAAACAAGAAGATACAGTCCACCCAGCCCAGAC
ACCCAGGGCCTGCTATCTTGTGCTAGGGCCAGGCATGGGGTGGCAGCTGGTGGCTGTGCAGCTA
GGGCTACGGCTGCTGCTGTTGATGCTGTCCCCGCAGACTCCCACCCATGGGCTGAGAAGCCTGG
CCACCCACACTCTACAAGCCCTCACCCCGCTCCTTTGATCACTTAGGGTGGGCAGTCAATAGAT
GGGGGTAATATTAGCGTCTCTCTGTTTATTCGCTCACAATAATACACGGCCCCTGGACGGGGAG
AGGGAGGGAGGGAGGAGGGTGAAAAGGAGGGAGGGGGAGGGGAGGAGGTACCTACTTCCCCGGC
CCCCCTCCCCTCTGTGCTTCGGGGGACAAGGAAGGGAGGGTGCTTCCCTTGACCCCCCAGAATG
TAAACAGCAGCAGATGAACAAAAATAAAATACAAAGGCCAGAGAAAAAAAAAAAAAAAAAAAAA
AAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001399381 ⟹ NP_001386310

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,516,076 - 104,521,018 (+)	NCBI
mRatBN7.2	1	95,379,590 - 95,384,532 (+)	NCBI

RefSeq Acc Id:

NM_001399382 ⟹ NP_001386311

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,516,076 - 104,521,018 (+)	NCBI
mRatBN7.2	1	95,379,590 - 95,384,532 (+)	NCBI

RefSeq Acc Id:

XM_006229060 ⟹ XP_006229122

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,515,782 - 104,524,591 (+)	NCBI
mRatBN7.2	1	95,379,605 - 95,384,310 (+)	NCBI
Rnor_6.0	1	100,891,833 - 100,896,589 (+)	NCBI
Rnor_5.0	1	101,956,459 - 101,961,429 (+)	NCBI

Sequence:

show sequence

GTCATGATTACTTCCGGCCGGGGCGGGGCCGGACCAGTTGGAGGGGCTGAATTGATGATCCCGC
TTCTCGCCCTTTGGCGGCTCCAAACAGCAGGCCACTTTGCCTACCCGCATGCTCCCAGATCCAC
ACCGAGAGTCTCCAGGGGCGTGACTTTCCGGGTGCGGGCTTCGAGATGGGGGATGACGGGCCAG
GAAGCACGGTGCATCTGCTGTGCCTCGCAGCCTCTAGCGGGGTTCCCCTGTTCTGTCGGAGCAG
CAGCGGAGGCGCCCCCTCCCGTCAACAGCTCCCTTTTTCTGTCATCGGGTCCCTCAATGGAGTC
CACATGTTCGGCCAGAATCTGGATGTGCAACTGAACTCCGCAAGAACAGAAGACACCACCGTAG
TGTGGAAGAACTTCCATGACAGCATCACCCTCATTGCTCTGTCATCTGAGGAGGGCACCTCTGA
GCTGAAGCTGGAAAGAATGCTCCACATGGTGTTTGGGGCCATGGTTCTCATTGTGGGACTTGAG
GAGCTGACCAATATCCGGAATGTAGAGAGACTGAAGAAAGAGCTGAGGGCCAGCTACTGTCTCA
TTGACAGCTTCCTGGGGAATTCAGAGCTCATCGGGGACCTGACCCAGTGTGTGGACTGTGTCAT
TCCTCCAGAGGGGTCTGTCATGCAGGAAACCCTCTCAGGGTTCGCAGAGGCCACTGGCACAGCC
TTTGTCAGCCTGCTGGTATCAGGCCGGGTGGTGGCAGCGACCGATGGCTGGTGGCGCCTAGGCA
TGCCTGAAGCCGTGCTACTCCCTTGGCTGGTGGGGTCCTTGCCACCGCAAGCTGCTCGTGACTA
CCCAGTGTACCTGCCCCACGGGAGCCCCACGGTCCCCCATCGGTTGTTGACCTTGACTCTGCTG
CGGGGCCTGGAGCTGTGTCTGCTCTGCGGGCCGCGCCCGCCCCTCGGTGAGCTGGACCCACAGT
TGCTGGAACGCTGGTGGCAGCCTCTGCTGGAGCCCCTCCGGGCTTGCCTGCCACTGGGCCCTAG
GGCGCTCCCTGACGGGTTCCCGCTACACAGCGATATTCTTGGCCTGTTGTTACTCCACTTGGAA
CTGAGACGCTGCCTCTTTACCGTGGAGCCCTCAAAGGATAAAGAACCGGGGCCAGCAGAGAAAC
AAGAAGATACAGTCCACCCAGCCCAGACACCCAGGGCCTGCTATCTTGTGCTAGGGCCAGGCAT
GGGGTGGCAGCTGGTGGCTGTGCAGCTAGGGCTACGGCTGCTGCTGTTGATGCTGTCCCCGCAG
ACTCCCACCCATGGGCTGAGAAGCCTGGCCACCCACACTCTACAAGCCCTCACCCCGCTCCTTT
GATCACTTAGGGTGGGCAGTCAATAGATGGGGGTAATATTA

hide sequence

RefSeq Acc Id:

XM_006229061 ⟹ XP_006229123

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,516,540 - 104,524,591 (+)	NCBI
mRatBN7.2	1	95,379,544 - 95,384,310 (+)	NCBI
Rnor_6.0	1	100,891,832 - 100,896,589 (+)	NCBI
Rnor_5.0	1	101,956,459 - 101,961,429 (+)	NCBI

Sequence:

show sequence

GGTCATGATTACTTCCGGCCGGGGCGGGGCCGGACCAGTTGGAGGGGCTGAATTGATGATCCCG
CTTCTCGCCCTTTGGCGGCTCCAAACAGCAGGCCACTTTGCCTACCCGCATGCTCCCAGATCCA
CACCGAGAGTCTCCAGGGGCGTGACTTTCCGGGTGCGGGCTTCGAGATGGGGGATGACGGGCCA
GGAAGCACGGTGCATCTGCTGTGCCTCGCAGCCTCTAGCGGGGTTCCCCTGTTCTGTCGGAGCA
GCAGCGGAGGCGCCCCCTCCCGTCAACAGCTCCCTTTTTCTGTCATCGGGTCCCTCAATGGAGT
CCACATGTTCGGCCAGAATCTGGATGTGCAACTGAACTCCGCAAGAACAGAAGACACCACCGTA
GTGTGGAAGAACTTCCATGACAGGTCCCTTGGCGGGAGCAAGGGAACAAGATCTGAGCAATGGT
TCCTGGCTTAGCATCACCCTCATTGCTCTGTCATCTGAGGAGGGCACCTCTGAGCTGAAGCTGG
AAAGAATGCTCCACATGGTGTTTGGGGCCATGGTTCTCATTGTGGGACTTGAGGAGCTGACCAA
TATCCGGAATGTAGAGAGACTGAAGAAAGAGCTGAGGGCCAGCTACTGTCTCATTGACAGCTTC
CTGGGGAATTCAGAGCTCATCGGGGACCTGACCCAGTGTGTGGACTGTGTCATTCCTCCAGAGG
GGTCTGTCATGCAGGAAACCCTCTCAGGGTTCGCAGAGGCCACTGGCACAGCCTTTGTCAGCCT
GCTGGTATCAGGCCGGGTGGTGGCAGCGACCGATGGCTGGTGGCGCCTAGGCATGCCTGAAGCC
GTGCTACTCCCTTGGCTGGTGGGGTCCTTGCCACCGCAAGCTGCTCGTGACTACCCAGTGTACC
TGCCCCACGGGAGCCCCACGGTCCCCCATCGGTTGTTGACCTTGACTCTGCTGCGGGGCCTGGA
GCTGTGTCTGCTCTGCGGGCCGCGCCCGCCCCTCGGTGAGCTGGACCCACAGTTGCTGGAACGC
TGGTGGCAGCCTCTGCTGGAGCCCCTCCGGGCTTGCCTGCCACTGGGCCCTAGGGCGCTCCCTG
ACGGGTTCCCGCTACACAGCGATATTCTTGGCCTGTTGTTACTCCACTTGGAACTGAGACGCTG
CCTCTTTACCGTGGAGCCCTCAAAGGATAAAGAGCCTTCCCCTGAGCAACGCAGGCGCCTCCTT
AGAAATTTCTATACGTTGGTGGCCACCACCCACTTCCCACCAGAACCGGGGCCAGCAGAGAAAC
AAGAAGATACAGTCCACCCAGCCCAGACACCCAGGGCCTGCTATCTTGTGCTAGGGCCAGGCAT
GGGGTGGCAGCTGGTGGCTGTGCAGCTAGGGCTACGGCTGCTGCTGTTGATGCTGTCCCCGCAG
ACTCCCACCCATGGGCTGAGAAGCCTGGCCACCCACACTCTACAAGCCCTCACCCCGCTCCTTT
GATCACTTAGGGTGGGCAGTCAATAGATGGGGGTAATATTA

hide sequence

RefSeq Acc Id:

XM_039112029 ⟹ XP_038967957

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,516,025 - 104,524,591 (+)	NCBI
mRatBN7.2	1	95,379,547 - 95,384,310 (+)	NCBI

RefSeq Acc Id:

XM_039112046 ⟹ XP_038967974

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,516,540 - 104,524,591 (+)	NCBI
mRatBN7.2	1	95,379,542 - 95,384,310 (+)	NCBI

RefSeq Acc Id:

XM_039112048 ⟹ XP_038967976

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,516,025 - 104,524,591 (+)	NCBI
mRatBN7.2	1	95,379,545 - 95,384,310 (+)	NCBI

RefSeq Acc Id:

XM_039112059 ⟹ XP_038967987

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,515,782 - 104,520,678 (+)	NCBI
mRatBN7.2	1	95,379,605 - 95,384,193 (+)	NCBI

RefSeq Acc Id:

XM_039112064 ⟹ XP_038967992

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,516,893 - 104,524,591 (+)	NCBI
mRatBN7.2	1	95,380,405 - 95,384,310 (+)	NCBI

RefSeq Acc Id:

XM_063261942 ⟹ XP_063118012

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,515,782 - 104,520,073 (+)	NCBI

RefSeq Acc Id:

XM_063261949 ⟹ XP_063118019

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,515,782 - 104,519,718 (+)	NCBI

RefSeq Acc Id:

XM_063261955 ⟹ XP_063118025

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,516,025 - 104,524,591 (+)	NCBI

RefSeq Acc Id:

XM_063261966 ⟹ XP_063118036

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,515,782 - 104,520,073 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001032735	(Get FASTA)	NCBI Sequence Viewer
	NP_001386310	(Get FASTA)	NCBI Sequence Viewer
	NP_001386311	(Get FASTA)	NCBI Sequence Viewer
	XP_006229122	(Get FASTA)	NCBI Sequence Viewer
	XP_006229123	(Get FASTA)	NCBI Sequence Viewer
	XP_038967957	(Get FASTA)	NCBI Sequence Viewer
	XP_038967974	(Get FASTA)	NCBI Sequence Viewer
	XP_038967976	(Get FASTA)	NCBI Sequence Viewer
	XP_038967987	(Get FASTA)	NCBI Sequence Viewer
	XP_038967992	(Get FASTA)	NCBI Sequence Viewer
	XP_063118012	(Get FASTA)	NCBI Sequence Viewer
	XP_063118019	(Get FASTA)	NCBI Sequence Viewer
	XP_063118025	(Get FASTA)	NCBI Sequence Viewer
	XP_063118036	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI07810	(Get FASTA)	NCBI Sequence Viewer
	EDM07442	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000070688
	ENSRNOP00000070688.1
	ENSRNOP00000074982
	ENSRNOP00000074982.1
	ENSRNOP00000076641.1
	ENSRNOP00000091471
	ENSRNOP00000091471.1
	ENSRNOP00055006866
	ENSRNOP00060009632
	ENSRNOP00065039896
GenBank Protein	Q3B756	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001032735 ⟸ NM_001037646
- Peptide Label:	isoform 2
- UniProtKB:	A0A8I5XV94 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGDDGPGSTVHLLCLAASSGVPLFCRSSSGGAPSRQQLPFSVIGSLNGVHMFGQNLDVQLNSAR TEDTTVVWKNFHDSITLIALSSEEGTSELKLERMLHMVFGAMVLIVGLEELTNIRNVERLKKEL RASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSVMQVPHRLLTLTLLRGLELCLLCGPRPPLGE LDPQLLERWWQPLLEPLRACLPLGPRALPDGFPLHSDILGLLLLHLELRRCLFTVEPSKDKEPS PEQRRRLLRNFYTLVATTHFPPEPGPAEKQEDTVHPAQTPRACYLVLGPGMGWQLVAVQLGLRL LLLMLSPQTPTHGLRSLATHTLQALTPLL hide sequence

RefSeq Acc Id:	XP_006229123 ⟸ XM_006229061
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I5XV94 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTGPLAGAREQDLSNGSWLSITLIALSSEEGTSELKLERMLHMVFGAMVLIVGLEELTNIRNVE RLKKELRASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSVMQETLSGFAEATGTAFVSLLVSGR VVAATDGWWRLGMPEAVLLPWLVGSLPPQAARDYPVYLPHGSPTVPHRLLTLTLLRGLELCLLC GPRPPLGELDPQLLERWWQPLLEPLRACLPLGPRALPDGFPLHSDILGLLLLHLELRRCLFTVE PSKDKEPSPEQRRRLLRNFYTLVATTHFPPEPGPAEKQEDTVHPAQTPRACYLVLGPGMGWQLV AVQLGLRLLLLMLSPQTPTHGLRSLATHTLQALTPLL hide sequence

RefSeq Acc Id:	XP_006229122 ⟸ XM_006229060
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6ABP8 (UniProtKB/TrEMBL), A0A8I5XV94 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGDDGPGSTVHLLCLAASSGVPLFCRSSSGGAPSRQQLPFSVIGSLNGVHMFGQNLDVQLNSAR TEDTTVVWKNFHDSITLIALSSEEGTSELKLERMLHMVFGAMVLIVGLEELTNIRNVERLKKEL RASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSVMQETLSGFAEATGTAFVSLLVSGRVVAATD GWWRLGMPEAVLLPWLVGSLPPQAARDYPVYLPHGSPTVPHRLLTLTLLRGLELCLLCGPRPPL GELDPQLLERWWQPLLEPLRACLPLGPRALPDGFPLHSDILGLLLLHLELRRCLFTVEPSKDKE PGPAEKQEDTVHPAQTPRACYLVLGPGMGWQLVAVQLGLRLLLLMLSPQTPTHGLRSLATHTLQ ALTPLL hide sequence

RefSeq Acc Id:

ENSRNOP00000070688 ⟸ ENSRNOT00000083336

RefSeq Acc Id:

ENSRNOP00000074982 ⟸ ENSRNOT00000086890

RefSeq Acc Id:	XP_038967974 ⟸ XM_039112046
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I5XV94 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038967976 ⟸ XM_039112048
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I5XV94 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038967957 ⟸ XM_039112029
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5XV94 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038967987 ⟸ XM_039112059
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038967992 ⟸ XM_039112064
- Peptide Label:	isoform X10

RefSeq Acc Id:

ENSRNOP00000076641 ⟸ ENSRNOT00000093831

RefSeq Acc Id:

ENSRNOP00000091471 ⟸ ENSRNOT00000114637

RefSeq Acc Id:	NP_001386310 ⟸ NM_001399381
- Peptide Label:	isoform 1
- UniProtKB:	Q3B756 (UniProtKB/Swiss-Prot), A6JAU2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386311 ⟸ NM_001399382
- Peptide Label:	isoform 3

RefSeq Acc Id:	XP_063118012 ⟸ XM_063261942
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063118036 ⟸ XM_063261966
- Peptide Label:	isoform X9

RefSeq Acc Id:	XP_063118019 ⟸ XM_063261949
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_063118025 ⟸ XM_063261955
- Peptide Label:	isoform X8

Protein Domains

FUZ/MON1/HPS1 first Longin FUZ/MON1/HPS1 second Longin FUZ/MON1/HPS1 third Longin

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q3B756-F1-model_v2	AlphaFold	Q3B756	1-415	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690013

Promoter ID:

EPDNEW_R538

Type:

initiation region

Name:

Fuz_1

Description:

fuzzy planar cell polarity protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	100,891,899 - 100,891,959	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310608	AgrOrtholog
BioCyc Gene	G2FUF-59744	BioCyc
Ensembl Genes	ENSRNOG00000053084	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055005614	UniProtKB/Swiss-Prot
	ENSRNOG00060007673	UniProtKB/Swiss-Prot
	ENSRNOG00065028226	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000083336	ENTREZGENE
	ENSRNOT00000083336.2	UniProtKB/Swiss-Prot
	ENSRNOT00000086890	ENTREZGENE
	ENSRNOT00000086890.2	UniProtKB/Swiss-Prot
	ENSRNOT00000093831.1	UniProtKB/TrEMBL
	ENSRNOT00000114637.1	UniProtKB/TrEMBL
	ENSRNOT00055009022	UniProtKB/Swiss-Prot
	ENSRNOT00060012696	UniProtKB/Swiss-Prot
	ENSRNOT00065048660	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7453736	IMAGE-MGC_LOAD
InterPro	FUZ/MON1/HPS1_longin_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FUZ/MON1/HPS1_longin_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FUZ/MON1/HPS1_longin_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Fuzzy	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:308577	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:125220	IMAGE-MGC_LOAD
NCBI Gene	308577	ENTREZGENE
PANTHER	PROTEIN FUZZY HOMOLOG	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR13559	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Fuz_longin_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Fuz_longin_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Fuz_longin_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Fuz	PhenoGen
RatGTEx	ENSRNOG00000053084	RatGTEx
	ENSRNOG00055005614	RatGTEx
	ENSRNOG00060007673	RatGTEx
	ENSRNOG00065028226	RatGTEx
UniProt	A0A8I5XV94	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ABP8	ENTREZGENE, UniProtKB/TrEMBL
	A6JAU2	ENTREZGENE, UniProtKB/TrEMBL
	FUZZY_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-03-20	Fuz	fuzzy planar cell polarity protein	Fuz	fuzzy homolog (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-27	Fuz	fuzzy homolog (Drosophila)	RGD1310608	similar to hypothetical protein FLJ22688	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1310608	similar to hypothetical protein FLJ22688	RGD1310608_predicted	similar to hypothetical protein FLJ22688 (predicted)	Symbol and Name status set to approved	1299863	APPROVED
2005-01-20	RGD1310608_predicted	similar to hypothetical protein FLJ22688 (predicted)	LOC308577_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC308577_predicted	similar to hypothetical protein FLJ22688 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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