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ONTOLOGY REPORT - ANNOTATIONS

Term:protein K48-linked ubiquitination
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Accession:GO:0070936 term browser browse the term
Definition:A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
Synonyms:exact_synonym: protein K48-linked polyubiquitination


show annotations for term's descendants           Sort by:
protein K48-linked ubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amfr autocrine motility factor receptor involved_in ISO
IBA		 (PMID:12847084), (PMID:24424410)
GO_REF:0000033		 RGD
GO_Central		 PMID:12847084 PMID:24424410 GO_REF:0000033 NCBI chr19:11,002,451...11,038,182
Ensembl chr19:10,996,099...11,032,247 		JBrowse link
G Anapc1 anaphase promoting complex subunit 1 involved_in ISO (PMID:29033132) RGD PMID:29033132 NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273 		JBrowse link
G Anapc10 anaphase promoting complex subunit 10 involved_in ISO (PMID:29033132) RGD PMID:29033132 NCBI chr19:28,152,299...28,205,552
Ensembl chr19:28,152,299...28,205,467 		JBrowse link
G Anapc11 anaphase promoting complex subunit 11 involved_in ISO (PMID:29033132) RGD PMID:29033132 NCBI chr10:106,373,610...106,384,633 JBrowse link
G Anapc13 anaphase promoting complex subunit 13 involved_in ISO (PMID:29033132) RGD PMID:29033132 NCBI chr 8:103,205,520...103,213,936
Ensembl chr 8:103,205,520...103,213,936 		JBrowse link
G Anapc15 anaphase promoting complex subunit 15 involved_in ISO
IEA
ISS		 (PMID:29033132)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29033132 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:156,238,640...156,266,005
Ensembl chr 1:156,262,841...156,268,145 		JBrowse link
G Anapc16 anaphase promoting complex subunit 16 involved_in ISO (PMID:29033132) RGD PMID:29033132 NCBI chr20:27,927,334...27,941,644
Ensembl chr20:27,927,334...27,941,984 		JBrowse link
G Anapc2 anaphase promoting complex subunit 2 involved_in ISO (PMID:29033132) RGD PMID:29033132 NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178 		JBrowse link
G Anapc4 anaphase promoting complex subunit 4 involved_in ISO (PMID:29033132) RGD PMID:29033132 NCBI chr14:58,125,995...58,159,253
Ensembl chr14:58,125,995...58,157,770 		JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 involved_in ISO
IEA
ISS		 (PMID:29033132)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29033132 GO_REF:0000024 GO_REF:0000107 NCBI chr12:33,748,709...33,781,709
Ensembl chr12:33,748,735...33,781,781 		JBrowse link
G Anapc7 anaphase promoting complex subunit 7 involved_in ISO (PMID:29033132) RGD PMID:29033132 NCBI chr12:34,131,214...34,160,819
Ensembl chr12:34,133,429...34,160,005 		JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 involved_in ISO (PMID:16118314), (PMID:19340006) RGD PMID:16118314 PMID:19340006 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852 		JBrowse link
G Bfar bifunctional apoptosis regulator involved_in ISO (PMID:21068390) RGD PMID:21068390 NCBI chr10:1,552,019...1,585,040
Ensembl chr10:1,552,072...1,585,038 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in		 ISO (PMID:29593216)
(PMID:38225265)		 RGD PMID:29593216 PMID:38225265 NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721 		JBrowse link
G Cdc16 cell division cycle 16 involved_in ISO (PMID:29033132) RGD PMID:29033132 NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550 		JBrowse link
G Cdc23 cell division cycle 23 involved_in ISO (PMID:29033132) RGD PMID:29033132 NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163 		JBrowse link
G Cdc26 cell division cycle 26 involved_in ISO
ISS		 (PMID:29033132)
GO_REF:0000024		 RGD
UniProt		 PMID:29033132 GO_REF:0000024 NCBI chr 5:75,844,852...75,859,830 JBrowse link
G Cdc27 cell division cycle 27 involved_in ISO
IEA
ISS		 (PMID:29033132)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29033132 GO_REF:0000024 GO_REF:0000107 NCBI chr10:89,900,676...89,949,770
Ensembl chr10:89,400,940...89,449,736 		JBrowse link
G Cdc34 cell division cycle 34, ubiquitin conjugating enzyme involved_in ISO (PMID:20061386) RGD PMID:20061386 NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186 		JBrowse link
G Cul1 cullin 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:15145941), (PMID:23263282)
(PMID:29593216)		 RGD PMID:15145941 PMID:23263282 PMID:29593216 NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980 		JBrowse link
G Cul3 cullin 3 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:25684205), (PMID:27708159)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:25684205 PMID:27708159 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:89,040,987...89,118,775
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:26479788) RGD PMID:26479788 NCBI chr11:64,814,926...64,824,539
Ensembl chr11:64,814,926...64,824,538 		JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 involved_in ISO (PMID:27692986) RGD PMID:27692986 NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818 		JBrowse link
G Fbxo38 F-box protein 38 involved_in ISO
IBA		 (PMID:30487606)
GO_REF:0000033		 RGD
GO_Central		 PMID:30487606 GO_REF:0000033 NCBI chr18:55,956,950...56,004,013
Ensembl chr18:55,956,959...56,003,961 		JBrowse link
G Fbxo45 F-box protein 45 involved_in IEA
ISO		 GO_REF:0000107
(PMID:29997255)		 Ensembl
RGD		 PMID:29997255 GO_REF:0000107 NCBI chr11:68,551,430...68,567,053
Ensembl chr11:68,551,122...68,566,800 		JBrowse link
G Fbxo7 F-box protein 7 involved_in ISO (PMID:36646384) RGD PMID:36646384 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Fbxo9 f-box protein 9 involved_in IEA
ISO		 GO_REF:0000107
(PMID:34480022)		 Ensembl
RGD		 PMID:34480022 GO_REF:0000107 NCBI chr 8:87,838,787...87,864,362
Ensembl chr 8:78,958,483...78,983,949 		JBrowse link
G Hace1 HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22036506)		 UniProt
RGD		 PMID:22036506 GO_REF:0000024 NCBI chr20:49,035,312...49,151,103
Ensembl chr20:49,035,648...49,151,103 		JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO
ISS		 (PMID:27746020)
GO_REF:0000024		 RGD
UniProt		 PMID:27746020 GO_REF:0000024 NCBI chr  X:20,873,795...21,001,378
Ensembl chr  X:20,873,795...21,001,262 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 involved_in ISO (PMID:27194766) RGD PMID:27194766 NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase involved_in ISO (PMID:19881509), (PMID:27736772), (PMID:30328013)
(PMID:18246070)		 RGD PMID:18246070 PMID:19881509 PMID:27736772 PMID:30328013 NCBI chr 3:164,102,490...164,193,932
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Kbtbd2 kelch repeat and BTB domain containing 2 involved_in ISO (PMID:27708159) RGD PMID:27708159 NCBI chr 4:86,027,947...86,050,266
Ensembl chr 4:86,027,947...86,050,211 		JBrowse link
G Kbtbd6 kelch repeat and BTB domain containing 6 involved_in ISO (PMID:25684205) RGD PMID:25684205 NCBI chr15:54,848,285...54,850,042
Ensembl chr15:54,848,446...54,850,453 		JBrowse link
G Kbtbd7 kelch repeat and BTB domain containing 7 involved_in ISO (PMID:25684205) RGD PMID:25684205 NCBI chr15:54,806,878...54,811,457
Ensembl chr15:54,806,873...54,811,687 		JBrowse link
G Kcmf1 potassium channel modulatory factor 1 involved_in ISO (PMID:38297121) RGD PMID:38297121 NCBI chr 4:104,888,452...104,950,234
Ensembl chr 4:104,889,847...104,950,234 		JBrowse link
G Klhl3 kelch-like family member 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23576762)		 UniProt
Ensembl
RGD		 PMID:23576762 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,523,089...6,645,971
Ensembl chr17:6,521,912...6,642,154 		JBrowse link
G Marchf6 membrane associated ring-CH-type finger 6 involved_in ISO (PMID:15673284) RGD PMID:15673284 NCBI chr 2:84,166,570...84,243,817
Ensembl chr 2:82,455,689...82,532,910 		JBrowse link
G Mycbp2 MYC binding protein 2 involved_in ISO (PMID:29997255) RGD PMID:29997255 NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase involved_in ISO (PMID:21463633) RGD PMID:21463633 NCBI chr18:60,663,918...60,996,824
Ensembl chr18:58,393,509...58,723,137 		JBrowse link
G Nmi N-myc (and STAT) interactor acts_upstream_of ISO (PMID:23956435) RGD PMID:23956435 NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:36,415,607...36,439,498 		JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II involved_in ISO (PMID:36159777) RGD PMID:36159777 NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:29883609)
(PMID:21874024)		 RGD PMID:21874024 PMID:29883609 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:21376232), (PMID:23858059)
GO_REF:0000107		 RGD
Ensembl		 PMID:21376232 PMID:23858059 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rbx1 ring-box 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:29593216)
(PMID:15103331), (PMID:25684205), (PMID:27708159), (PMID:29658272)		 RGD PMID:15103331 PMID:25684205 PMID:27708159 PMID:29593216 PMID:29658272 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18450452), (PMID:22609986)		 UniProt
Ensembl
RGD		 PMID:18450452 PMID:22609986 GO_REF:0000024 GO_REF:0000107 NCBI chr10:67,740,711...67,803,669
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO (PMID:23418353) RGD PMID:23418353 NCBI chr 2:184,262,087...184,329,839
Ensembl chr 2:184,262,371...184,329,823 		JBrowse link
G Rnf126 ring finger protein 126 involved_in ISO (PMID:23418353) RGD PMID:23418353 NCBI chr 7:9,939,359...9,946,963
Ensembl chr 7:9,938,229...9,946,738 		JBrowse link
G Rnf146 ring finger protein 146 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21478859)		 UniProt
Ensembl
RGD		 PMID:21478859 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:30,286,680...30,304,367
Ensembl chr 1:28,458,887...28,475,923 		JBrowse link
G Rnf152 ring finger protein 152 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21203937)		 UniProt
RGD		 PMID:21203937 GO_REF:0000024 NCBI chr13:21,838,634...21,918,000
Ensembl chr13:21,323,824...21,403,113 		JBrowse link
G Rnf170 ring finger protein 170 acts_upstream_of_or_within ISO (PMID:31076723) RGD PMID:31076723 NCBI chr16:65,928,886...65,954,092
Ensembl chr16:65,928,895...65,954,083 		JBrowse link
G Rnf187 ring finger protein 187 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20852630)		 UniProt
RGD		 PMID:20852630 GO_REF:0000024 NCBI chr10:43,709,493...43,715,392
Ensembl chr10:43,702,357...43,716,157 		JBrowse link
G Rnf216 ring finger protein 216 involved_in ISO (PMID:19893624) RGD PMID:19893624 NCBI chr12:11,454,752...11,576,305
Ensembl chr12:11,454,797...11,576,304 		JBrowse link
G Rnf34 ring finger protein 34 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:25012219)		 UniProt
Ensembl
RGD		 PMID:25012219 GO_REF:0000024 GO_REF:0000107 NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586 		JBrowse link
G Rnf4 ring finger protein 4 involved_in IDA PMID:18408734 UniProt PMID:18408734 RGD:8553731 NCBI chr14:80,625,864...80,647,138
Ensembl chr14:76,401,299...76,422,566 		JBrowse link
G Rnf5 ring finger protein 5 involved_in ISO (PMID:19285439) RGD PMID:19285439 NCBI chr20:4,145,539...4,147,985
Ensembl chr20:4,145,507...4,147,985 		JBrowse link
G Rnf6 ring finger protein 6 involved_in ISO (PMID:16204183) RGD PMID:16204183 NCBI chr12:8,816,797...8,826,870
Ensembl chr12:8,816,833...8,826,847 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:21911360), (PMID:22266820), (PMID:22373579)		 UniProt
GO_Central
RGD		 PMID:21911360 PMID:22266820 PMID:22373579 GO_REF:0000024 GO_REF:0000033 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491 		JBrowse link
G Skp1 S-phase kinase-associated protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:29593216)
(PMID:15145941), (PMID:23263282), (PMID:29997255)		 Ensembl
RGD		 PMID:15145941 PMID:23263282 PMID:29593216 PMID:29997255 GO_REF:0000107 NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388 		JBrowse link
G Skp2 S-phase kinase associated protein 2 involved_in ISO (PMID:27194766) RGD PMID:27194766 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Spsb3 splA/ryanodine receptor domain and SOCS box containing 3 involved_in ISO (PMID:38418882) RGD PMID:38418882 NCBI chr10:13,907,175...13,912,841
Ensembl chr10:13,907,253...13,912,841 		JBrowse link
G Syvn1 synoviolin 1 involved_in ISO (PMID:14593114) RGD PMID:14593114 NCBI chr 1:212,766,736...212,775,426
Ensembl chr 1:203,339,619...203,346,152 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:15258597) RGD PMID:15258597 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Topors TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase involved_in ISO (PMID:15247280) RGD PMID:15247280 NCBI chr 5:55,388,033...55,399,937
Ensembl chr 5:55,387,632...55,399,937 		JBrowse link
G Trim21 tripartite motif-containing 21 involved_in ISO (PMID:36359729) RGD PMID:36359729 NCBI chr 1:156,964,896...156,987,504
Ensembl chr 1:156,964,913...156,987,440 		JBrowse link
G Trim25 tripartite motif-containing 25 involved_in ISO (PMID:36075446) RGD PMID:36075446 NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257 		JBrowse link
G Trim31 tripartite motif-containing 31 involved_in ISO (PMID:27929086) RGD PMID:27929086 NCBI chr20:1,658,386...1,671,711
Ensembl chr20:1,653,165...1,666,494 		JBrowse link
G Trim38 tripartite motif containing 38 acts_upstream_of_or_within ISO (PMID:22539786) RGD PMID:22539786 NCBI chr17:41,351,857...41,365,021 JBrowse link
G Trim45 tripartite motif-containing 45 involved_in ISO (PMID:36681779) RGD PMID:36681779 NCBI chr 2:188,349,979...188,359,205
Ensembl chr 2:188,349,744...188,359,204 		JBrowse link
G Trim55 tripartite motif-containing 55 involved_in IEA
ISO		 GO_REF:0000107
(PMID:37816088)		 Ensembl
RGD		 PMID:37816088 GO_REF:0000107 NCBI chr 2:102,100,229...102,142,173
Ensembl chr 2:102,088,443...102,142,168 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218) RGD PMID:24882218 NCBI chr 1:168,095,619...168,108,809
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Trim65 tripartite motif-containing 65 involved_in ISO (PMID:31310649), (PMID:34512673) RGD PMID:31310649 PMID:34512673 NCBI chr10:101,847,822...101,863,052
Ensembl chr10:101,357,937...101,364,971 		JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 involved_in ISO
IEA		 (PMID:20059950)
GO_REF:0000107		 RGD
Ensembl		 PMID:20059950 GO_REF:0000107 NCBI chr11:33,689,119...33,788,976
Ensembl chr11:33,688,952...33,788,975 		JBrowse link
G Ube2a ubiquitin-conjugating enzyme E2A involved_in ISO (PMID:20061386), (PMID:38297121) RGD PMID:20061386 PMID:38297121 NCBI chr  X:116,114,339...116,125,076
Ensembl chr  X:116,113,875...116,125,070 		JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:20061386)		 UniProt
Ensembl
RGD		 PMID:20061386 GO_REF:0000024 GO_REF:0000107 NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C involved_in ISO (PMID:20061386) RGD PMID:20061386 NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:153,506,636...153,513,339 		JBrowse link
G Ube2d1 ubiquitin-conjugating enzyme E2D 1 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:20061386)		 UniProt
GO_Central
Ensembl
RGD		 PMID:20061386 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:17,309,315...17,343,770
Ensembl chr20:17,309,315...17,342,295 		JBrowse link
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:20061386)		 UniProt
GO_Central
RGD		 PMID:20061386 GO_REF:0000024 GO_REF:0000033 NCBI chr18:27,364,325...27,406,322
Ensembl chr18:27,364,303...27,406,181 		JBrowse link
G Ube2d2b ubiquitin-conjugating enzyme E2D 2B involved_in ISO
IBA		 (PMID:20061386)
GO_REF:0000033		 RGD
GO_Central		 PMID:20061386 GO_REF:0000033 NCBI chr14:1,915,999...1,917,473
Ensembl chr14:1,916,845...1,917,416 		JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:20061386)		 UniProt
GO_Central
RGD		 PMID:20061386 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081 		JBrowse link
G Ube2d4l1 ubiquitin-conjugating enzyme E2D 4 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:77,278,354...77,279,285
Ensembl chr  X:77,278,343...77,279,293 		JBrowse link
G Ube2e1 ubiquitin-conjugating enzyme E2E 1 involved_in ISO
IBA		 (PMID:20061386)
GO_REF:0000033		 RGD
GO_Central		 PMID:20061386 GO_REF:0000033 NCBI chr15:7,439,751...7,493,410
Ensembl chr15:7,439,759...7,493,400 		JBrowse link
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 involved_in ISO
IBA		 (PMID:20061386)
GO_REF:0000033		 RGD
GO_Central		 PMID:20061386 GO_REF:0000033 NCBI chr15:6,980,241...7,257,912
Ensembl chr15:6,980,474...7,257,532 		JBrowse link
G Ube2e3 ubiquitin-conjugating enzyme E2E 3 involved_in ISO
IBA		 (PMID:20061386)
GO_REF:0000033		 RGD
GO_Central		 PMID:20061386 GO_REF:0000033 NCBI chr 3:63,786,976...63,851,400
Ensembl chr 3:63,786,650...63,843,237 		JBrowse link
G Ube2g1 ubiquitin-conjugating enzyme E2G 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12847084)
(PMID:14593114), (PMID:20061386)		 UniProt
RGD		 PMID:12847084 PMID:14593114 PMID:20061386 GO_REF:0000024 NCBI chr10:57,225,963...57,306,748
Ensembl chr10:57,225,952...57,308,568 		JBrowse link
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 involved_in ISO (PMID:20061386) RGD PMID:20061386 NCBI chr20:10,983,734...11,005,468
Ensembl chr20:10,983,742...11,005,447 		JBrowse link
G Ube2h ubiquitin-conjugating enzyme E2H involved_in ISO (PMID:20061386) RGD PMID:20061386 NCBI chr 4:58,834,674...58,930,156
Ensembl chr 4:58,834,674...58,930,156 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K involved_in ISO (PMID:20061386) RGD PMID:20061386 NCBI chr14:43,011,681...43,077,825
Ensembl chr14:42,658,016...42,718,630 		JBrowse link
G Ube2q2 ubiquitin conjugating enzyme E2 Q2 involved_in ISO (PMID:20061386) RGD PMID:20061386 NCBI chr 8:55,518,402...55,578,342
Ensembl chr 8:55,519,147...55,577,212 		JBrowse link
G Ube2r2 ubiquitin-conjugating enzyme E2R 2 involved_in ISO (PMID:20061386) RGD PMID:20061386 NCBI chr 5:56,286,604...56,345,160
Ensembl chr 5:56,286,725...56,345,513 		JBrowse link
G Ube2t ubiquitin-conjugating enzyme E2T involved_in ISO (PMID:20061386) RGD PMID:20061386 NCBI chr13:46,403,352...46,413,854
Ensembl chr13:46,403,375...46,414,835 		JBrowse link
G Ube3a ubiquitin protein ligase E3A involved_in ISO (PMID:12890688) RGD PMID:12890688 NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250 		JBrowse link
G Ube3c ubiquitin protein ligase E3C involved_in ISO (PMID:11278995), (PMID:32039437)
(PMID:33637724)		 RGD PMID:11278995 PMID:32039437 PMID:33637724 NCBI chr 4:5,648,932...5,749,922
Ensembl chr 4:5,648,690...5,750,011 		JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 involved_in ISO
IEA
ISS		 (PMID:29033132), (PMID:38297121)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29033132 PMID:38297121 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:28689657), (PMID:29033132), (PMID:29378950), (PMID:37620400)		 Ensembl
RGD		 PMID:28689657 PMID:29033132 PMID:29378950 PMID:37620400 GO_REF:0000107 NCBI chr 7:69,115,216...69,224,843
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
G Znrf1 zinc and ring finger 1 involved_in IBA
ISO		 GO_REF:0000033
(PMID:22057101)		 GO_Central
RGD		 PMID:22057101 GO_REF:0000033 NCBI chr19:39,496,414...39,581,600
Ensembl chr19:39,496,527...39,580,969 		JBrowse link
G Znrf2 zinc and ring finger 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:83,950,406...84,032,676
Ensembl chr 4:83,949,309...84,027,818 		JBrowse link
negative regulation of protein K48-linked ubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppia peptidylprolyl isomerase A involved_in ISO
ISS		 (PMID:30328013)
GO_REF:0000024		 RGD
UniProt		 PMID:30328013 GO_REF:0000024 NCBI chr14:85,491,223...85,496,884
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,361,379...21,362,147
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Trim44 tripartite motif-containing 44 involved_in ISO
IEA		 (PMID:23460740)
GO_REF:0000107		 RGD
Ensembl		 PMID:23460740 GO_REF:0000107 NCBI chr 3:88,593,619...88,729,085
Ensembl chr 3:88,592,719...88,729,188 		JBrowse link
positive regulation of protein K48-linked ubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat-containing 2 involved_in ISO (PMID:21931591) RGD PMID:21931591 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Gabarap GABA type A receptor-associated protein involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:25684205)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:25684205 GO_REF:0000024 GO_REF:0000107 NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765 		JBrowse link
G Nmi N-myc (and STAT) interactor acts_upstream_of_or_within ISO (PMID:23956435) RGD PMID:23956435 NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:36,415,607...36,439,498 		JBrowse link
regulation of protein K48-linked ubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tcf25 TCF25 ribosome quality control complex subunit involved_in ISO (PMID:30244831) RGD PMID:30244831 NCBI chr19:51,415,341...51,449,725
Ensembl chr19:51,415,543...51,449,723 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      metabolic process 12181
        macromolecule metabolic process 9999
          protein metabolic process 5230
            protein modification process 2603
              post-translational protein modification 945
                protein modification by small protein conjugation or removal 894
                  protein modification by small protein conjugation 766
                    protein ubiquitination 705
                      protein polyubiquitination 270
                        protein K48-linked ubiquitination 102
                          negative regulation of protein K48-linked ubiquitination 3
                          positive regulation of protein K48-linked ubiquitination 3
                          regulation of protein K48-linked ubiquitination + 7
paths to the root