Spsb3 (splA/ryanodine receptor domain and SOCS box containing 3) - Rat Genome Database

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Gene: Spsb3 (splA/ryanodine receptor domain and SOCS box containing 3) Rattus norvegicus
Analyze
Symbol: Spsb3
Name: splA/ryanodine receptor domain and SOCS box containing 3
RGD ID: 1310936
Description: Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human SPSB3 (splA/ryanodine receptor domain and SOCS box containing 3); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC302981; SPRY domain-containing SOCS box protein 3; T-complex expressed gene 1; Tce1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21013,907,175 - 13,912,841 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1013,907,253 - 13,912,841 (+)Ensembl
Rnor_6.01014,248,199 - 14,253,815 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,248,399 - 14,253,815 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01014,064,726 - 14,069,831 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,135,818 - 14,140,923 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11014,136,129 - 14,140,924 (+)NCBI
Celera1013,586,941 - 13,592,046 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Spsb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21013,907,175 - 13,912,841 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1013,907,253 - 13,912,841 (+)Ensembl
Rnor_6.01014,248,199 - 14,253,815 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,248,399 - 14,253,815 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01014,064,726 - 14,069,831 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,135,818 - 14,140,923 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11014,136,129 - 14,140,924 (+)NCBI
Celera1013,586,941 - 13,592,046 (+)NCBICelera
Cytogenetic Map10q12NCBI
SPSB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,776,712 - 1,782,571 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl161,776,712 - 1,793,700 (-)EnsemblGRCh38hg38GRCh38
GRCh37161,826,713 - 1,832,572 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,766,714 - 1,772,582 (-)NCBINCBI36hg18NCBI36
Celera162,038,990 - 2,044,859 (-)NCBI
Cytogenetic Map16p13.3NCBI
HuRef161,749,609 - 1,755,478 (-)NCBIHuRef
CHM1_1161,826,661 - 1,832,529 (-)NCBICHM1_1
T2T-CHM13v2.0161,792,547 - 1,798,407 (-)NCBI
Spsb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,104,956 - 25,111,124 (+)NCBIGRCm39mm39
GRCm39 Ensembl1725,105,617 - 25,111,126 (+)Ensembl
GRCm381724,885,982 - 24,892,150 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,886,643 - 24,892,152 (+)EnsemblGRCm38mm10GRCm38
MGSCv371725,023,619 - 25,029,092 (+)NCBIGRCm37mm9NCBIm37
MGSCv361724,615,081 - 24,619,747 (+)NCBImm8
Celera1725,413,484 - 25,418,837 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
Spsb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,487,475 - 15,493,422 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,486,845 - 15,493,422 (+)NCBIChiLan1.0ChiLan1.0
SPSB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1161,830,040 - 1,835,499 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl161,830,040 - 1,835,504 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v016399,090 - 405,020 (-)NCBIMhudiblu_PPA_v0panPan3
SPSB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,122,148 - 39,127,444 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,122,247 - 39,127,446 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,361,044 - 40,366,240 (+)NCBI
ROS_Cfam_1.0639,438,582 - 39,443,761 (+)NCBI
ROS_Cfam_1.0 Ensembl639,438,588 - 39,443,757 (+)Ensembl
UMICH_Zoey_3.1639,115,275 - 39,120,468 (+)NCBI
UNSW_CanFamBas_1.0639,087,856 - 39,093,050 (+)NCBI
UU_Cfam_GSD_1.0639,566,315 - 39,571,495 (+)NCBI
Spsb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,492,050 - 104,497,453 (-)NCBI
SpeTri2.0NW_0049366942,212,022 - 2,217,409 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPSB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,185,014 - 40,190,518 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1340,184,534 - 40,190,519 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,622,709 - 41,626,519 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPSB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,685,741 - 1,691,542 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl51,686,095 - 1,691,489 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606829,394,945 - 29,400,809 (+)NCBIVero_WHO_p1.0
Spsb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913470,002 - 475,765 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_004624913469,732 - 475,767 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH134784  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,909,292 - 13,909,491 (+)MAPPERmRatBN7.2
Rnor_6.01014,250,270 - 14,250,468NCBIRnor6.0
Rnor_5.01014,066,286 - 14,066,484UniSTSRnor5.0
RGSC_v3.41014,137,378 - 14,137,576UniSTSRGSC3.4
Celera1013,588,501 - 13,588,699UniSTS
Cytogenetic Map10q12UniSTS
RH138928  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,911,961 - 13,912,121 (+)MAPPERmRatBN7.2
Rnor_6.01014,252,939 - 14,253,098NCBIRnor6.0
Rnor_5.01014,068,955 - 14,069,114UniSTSRnor5.0
RGSC_v3.41014,140,047 - 14,140,206UniSTSRGSC3.4
Celera1013,591,170 - 13,591,329UniSTS
RH 3.4 Map10172.3UniSTS
Cytogenetic Map10q12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10615418215990232Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:51
Count of miRNA genes:50
Interacting mature miRNAs:50
Transcripts:ENSRNOT00000020733
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC130925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000020733   ⟹   ENSRNOP00000020733
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,907,253 - 13,912,841 (+)Ensembl
Rnor_6.0 Ensembl1014,248,710 - 14,253,815 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077689   ⟹   ENSRNOP00000071059
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,907,461 - 13,912,841 (+)Ensembl
Rnor_6.0 Ensembl1014,248,399 - 14,253,563 (+)Ensembl
RefSeq Acc Id: NM_001106988   ⟹   NP_001100458
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,733 - 13,912,838 (+)NCBI
Rnor_6.01014,248,710 - 14,253,815 (+)NCBI
Rnor_5.01014,064,726 - 14,069,831 (+)NCBI
RGSC_v3.41014,135,818 - 14,140,923 (+)RGD
Celera1013,586,941 - 13,592,046 (+)RGD
Sequence:
RefSeq Acc Id: XM_017597221   ⟹   XP_017452710
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,175 - 13,912,841 (+)NCBI
Rnor_6.01014,248,199 - 14,253,813 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597222   ⟹   XP_017452711
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,175 - 13,912,841 (+)NCBI
Rnor_6.01014,248,200 - 14,253,813 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597223   ⟹   XP_017452712
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,175 - 13,912,841 (+)NCBI
Rnor_6.01014,248,200 - 14,253,813 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597224   ⟹   XP_017452713
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,687 - 13,912,841 (+)NCBI
Rnor_6.01014,248,656 - 14,253,813 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597226   ⟹   XP_017452715
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,323 - 13,912,841 (+)NCBI
Rnor_6.01014,248,300 - 14,253,813 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597227   ⟹   XP_017452716
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,334 - 13,912,841 (+)NCBI
Rnor_6.01014,248,311 - 14,253,813 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597228   ⟹   XP_017452717
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,290 - 13,912,841 (+)NCBI
Rnor_6.01014,248,267 - 14,253,813 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597229   ⟹   XP_017452718
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,290 - 13,912,841 (+)NCBI
Rnor_6.01014,248,267 - 14,253,813 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039085866   ⟹   XP_038941794
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,334 - 13,912,841 (+)NCBI
RefSeq Acc Id: XM_039085867   ⟹   XP_038941795
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,192 - 13,912,841 (+)NCBI
RefSeq Acc Id: XM_039085868   ⟹   XP_038941796
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,685 - 13,912,841 (+)NCBI
RefSeq Acc Id: XM_039085869   ⟹   XP_038941797
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,837 - 13,912,841 (+)NCBI
RefSeq Acc Id: XM_039085870   ⟹   XP_038941798
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,690 - 13,912,841 (+)NCBI
RefSeq Acc Id: XM_039085871   ⟹   XP_038941799
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,907,842 - 13,912,841 (+)NCBI
RefSeq Acc Id: XM_039085872   ⟹   XP_038941800
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21013,908,336 - 13,912,841 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001100458   ⟸   NM_001106988
- UniProtKB: D3ZVU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452710   ⟸   XM_017597221
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017452711   ⟸   XM_017597222
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017452712   ⟸   XM_017597223
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017452717   ⟸   XM_017597228
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017452718   ⟸   XM_017597229
- Peptide Label: isoform X8
- UniProtKB: A0A0G2JZI4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452715   ⟸   XM_017597226
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017452716   ⟸   XM_017597227
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017452713   ⟸   XM_017597224
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000071059   ⟸   ENSRNOT00000077689
RefSeq Acc Id: ENSRNOP00000020733   ⟸   ENSRNOT00000020733
RefSeq Acc Id: XP_038941795   ⟸   XM_039085867
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038941794   ⟸   XM_039085866
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038941796   ⟸   XM_039085868
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038941798   ⟸   XM_039085870
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038941797   ⟸   XM_039085869
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038941799   ⟸   XM_039085871
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038941800   ⟸   XM_039085872
- Peptide Label: isoform X9

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZVU8-F1-model_v2 AlphaFold D3ZVU8 1-391 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
10 14252107 14252108 T A snv SBN/Ygl (MCW), SBH/Ygl (MCW), CDS, CDR, SBN/Ygl (RGD)
10 14252541 14252542 G A snv CDS, SBN/Ygl (RGD), SBN/Ygl (MCW), SBH/Ygl (MCW), CDR
10 14253306 14253307 G A snv CDR, CDS, SBH/Ygl (MCW), SBH/Ygl (RGD), SBN/Ygl (MCW), SBN/Ygl (RGD)


Assembly: Rnor_5.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
10 14068557 14068558 G A snv SBH/Ygl (MCW), SBN/Ygl (MCW), BDIX.Cg-Tal/NemOda (KyushuU), IS-Tlk/Kyo (KyushuU), BDIX/NemOda (KyushuU), IS/Kyo (KyushuU)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310936 AgrOrtholog
BioCyc Gene G2FUF-25816 BioCyc
Ensembl Genes ENSRNOG00000015300 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000020733 ENTREZGENE
  ENSRNOP00000020733.5 UniProtKB/TrEMBL
  ENSRNOP00000071059.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020733 ENTREZGENE
  ENSRNOT00000020733.6 UniProtKB/TrEMBL
  ENSRNOT00000077689.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
InterPro B30.2/SPRY_sf UniProtKB/TrEMBL
  B302 UniProtKB/TrEMBL
  ConA-like_dom UniProtKB/TrEMBL
  SOCS_C UniProtKB/TrEMBL
  SPRY_rcpt UniProtKB/TrEMBL
  SPRY_SPSB3 UniProtKB/TrEMBL
KEGG Report rno:302981 UniProtKB/TrEMBL
NCBI Gene 302981 ENTREZGENE
Pfam SPRY UniProtKB/TrEMBL
PhenoGen Spsb3 PhenoGen
PROSITE B302_SPRY UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
SMART SPRY UniProtKB/TrEMBL
Superfamily-SCOP ConA_like_lec_gl UniProtKB/TrEMBL
UniProt A0A0G2JZI4 ENTREZGENE, UniProtKB/TrEMBL
  D3ZVU8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Spsb3  splA/ryanodine receptor domain and SOCS box containing 3   Spsb3_predicted  splA/ryanodine receptor domain and SOCS box containing 3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Spsb3_predicted  splA/ryanodine receptor domain and SOCS box containing 3 (predicted)  Tce1_predicted  T-complex expressed gene 1 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Tce1_predicted  T-complex expressed gene 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED