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ONTOLOGY REPORT - ANNOTATIONS

Term:adherens junction organization
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Accession:GO:0034332 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
Synonyms:exact_synonym: adherens junction organisation
 never_in_taxon: NCBITaxon:4751 ! Fungi


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adherens junction organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 involved_in ISO
IEA		 (MGI:6316556|PMID:30639848)
GO_REF:0000107		 RGD
Ensembl		 PMID:30639848 GO_REF:0000107 MGI:6316556 NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889 		JBrowse link
G Cdc42 cell division cycle 42 acts_upstream_of_or_within ISO MGI:3619134 (PMID:16892058) RGD PMID:16892058 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cdh1 cadherin 1 involved_in ISO
IBA		 (PMID:21724833)
GO_REF:0000033		 RGD
GO_Central		 PMID:21724833 GO_REF:0000033 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh10 cadherin 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995 		JBrowse link
G Cdh11 cadherin 11 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272 		JBrowse link
G Cdh12 cadherin 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:70,474,679...71,705,369
Ensembl chr 2:70,475,043...71,700,572 		JBrowse link
G Cdh13 cadherin 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cdh15 cadherin 15 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105 		JBrowse link
G Cdh17 cadherin 17 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884 		JBrowse link
G Cdh18 cadherin 18 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:72,818,076...73,820,144
Ensembl chr 2:73,345,005...73,820,138 		JBrowse link
G Cdh19 cadherin 19 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:27,935,915...28,047,490
Ensembl chr13:27,936,668...28,019,310 		JBrowse link
G Cdh2 cadherin 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdh20 cadherin 20 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:20,737,640...21,069,746
Ensembl chr13:20,738,081...21,068,676 		JBrowse link
G Cdh22 cadherin 22 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:153,845,563...153,970,630
Ensembl chr 3:153,845,787...153,970,588 		JBrowse link
G Cdh24 cadherin 24 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:28,091,578...28,101,330
Ensembl chr15:28,091,637...28,101,340 		JBrowse link
G Cdh26 cadherin 26 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149 		JBrowse link
G Cdh3 cadherin 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084 		JBrowse link
G Cdh5 cadherin 5 involved_in ISO
IBA		 (PMID:26598555)
GO_REF:0000033		 RGD
GO_Central		 PMID:26598555 GO_REF:0000033 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368 		JBrowse link
G Cdh6 cadherin 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:62,079,139...62,225,298
Ensembl chr 2:62,079,137...62,225,228 		JBrowse link
G Cdh7 cadherin 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:26,672,058...26,821,571
Ensembl chr13:26,672,484...26,819,846 		JBrowse link
G Cdh8 cadherin 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:5,494,038...5,901,810
Ensembl chr19:5,494,174...5,895,669 		JBrowse link
G Cdh9 cadherin 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:66,280,422...66,367,121
Ensembl chr 2:66,228,117...66,367,121 		JBrowse link
G Csk C-terminal Src kinase involved_in IEP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:15389520 GO_REF:0000033, RGD:5134367 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO (PMID:19129494) RGD PMID:19129494 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dsp desmoplakin acts_upstream_of_or_within ISO MGI:1926500|MGI:2156542 (PMID:11781569) RGD PMID:11781569 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800 		JBrowse link
G Efnb2 ephrin B2 involved_in ISO (MGI:6316556|PMID:30639848) RGD PMID:30639848 MGI:6316556 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO (MGI:6316556|PMID:30639848) RGD PMID:30639848 MGI:6316556 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Numb NUMB, endocytic adaptor protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:894702 (PMID:17589506)		 Ensembl
RGD		 PMID:17589506 GO_REF:0000107 NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354 		JBrowse link
G Numbl NUMB-like, endocytic adaptor protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:107423 (PMID:17589506)		 Ensembl
RGD		 PMID:17589506 GO_REF:0000107 NCBI chr 1:82,549,814...82,573,788
Ensembl chr 1:82,550,054...82,573,776 		JBrowse link
G Plec plectin involved_in IEA
ISO		 GO_REF:0000107
MGI:3721885 (PMID:26519478)		 Ensembl
RGD		 PMID:26519478 GO_REF:0000107 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within ISO MGI:4124253 (PMID:26787558) RGD PMID:26787558 NCBI chr20:13,337,983...13,443,665
Ensembl chr20:13,339,692...13,443,665 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:15389520 RGD:5134367 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
adherens junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta involved_in ISO
IEA		 (PMID:22855531)
GO_REF:0000107		 RGD
Ensembl		 PMID:22855531 GO_REF:0000107 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
ISS		 (PMID:20086044), (PMID:20123964)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20086044 PMID:20123964 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fer FER tyrosine kinase IEP RGD PMID:12700184 RGD:2291909 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5494340|PMID:23565059)		 Ensembl
RGD		 PMID:23565059 GO_REF:0000107 MGI:5494340 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902 		JBrowse link
G Jam3 junctional adhesion molecule 3 involved_in ISO
IEA		 (PMID:19060272)
GO_REF:0000107		 RGD
Ensembl		 PMID:19060272 GO_REF:0000107 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816 		JBrowse link
G Ramp2 receptor activity modifying protein 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3772552|PMID:18097473)
(PMID:18097473)		 UniProt
RGD		 PMID:18097473 GO_REF:0000024 MGI:3772552 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA		 (PMID:18593713)
GO_REF:0000107		 RGD
Ensembl		 PMID:18593713 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Tbcd tubulin folding cofactor D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:106,717,340...106,874,126
Ensembl chr10:106,717,367...106,874,122 		JBrowse link
G Vcl vinculin involved_in IEA
ISO		 GO_REF:0000107
(PMID:20086044)		 Ensembl
RGD		 PMID:20086044 GO_REF:0000107 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606 		JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (MGI:4940410|PMID:21317240) RGD PMID:21317240 MGI:4940410 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677 		JBrowse link
adherens junction disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fer FER tyrosine kinase IEP RGD PMID:12700184 RGD:2291909 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
adherens junction maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afdn afadin, adherens junction formation factor acts_upstream_of_or_within ISO (PMID:25100583) RGD PMID:25100583 NCBI chr 1:53,905,344...54,034,216
Ensembl chr 1:53,905,373...54,034,216 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:28799653)
(MGI:6467695|PMID:28799653)		 RGD PMID:28799653 MGI:6467695 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Inava innate immunity activator involved_in ISO
IBA		 (PMID:29420262)
GO_REF:0000033
(MGI:6119883|PMID:29420262)		 RGD
GO_Central		 PMID:29420262 GO_REF:0000033 MGI:6119883 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:5319219 (PMID:21406566)		 GO_Central
RGD		 PMID:21406566 GO_REF:0000033 NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968 		JBrowse link
G Pkp2 plakophilin 2 IMP RGD PMID:18261826 RGD:6784508 NCBI chr11:84,661,783...84,727,730
Ensembl chr11:84,661,783...84,727,730 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
negative regulation of adherens junction organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:26598555) RGD PMID:26598555 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Rdx radixin involved_in ISO (PMID:22467863) RGD PMID:22467863 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO
IEA		 (PMID:26598555)
GO_REF:0000107		 RGD
Ensembl		 PMID:26598555 GO_REF:0000107 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
positive regulation of adherens junction organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 involved_in ISO
IEA
IBA		 (PMID:25978380)
GO_REF:0000107
(MGI:5796260|PMID:25978380)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:25978380 GO_REF:0000033 GO_REF:0000107 MGI:5796260 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182 		JBrowse link
G Ptpn23 protein tyrosine phosphatase, non-receptor type 23 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21724833)		 Ensembl
RGD		 PMID:21724833 GO_REF:0000107 NCBI chr 8:110,360,804...110,383,271
Ensembl chr 8:110,360,804...110,383,271 		JBrowse link
zonula adherens assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 involved_in ISO (PMID:15572692) RGD PMID:15572692 NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699 		JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 acts_upstream_of_or_within ISO MGI:3757646 (PMID:17765678) RGD PMID:17765678 NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837 		JBrowse link
zonula adherens maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19041755)		 UniProt
RGD		 PMID:19041755 GO_REF:0000024 NCBI chr12:1,643,062...1,666,685
Ensembl chr12:1,643,251...1,666,685 		JBrowse link
G Kifc3 kinesin family member C3 involved_in ISO (PMID:19041755) RGD PMID:19041755 NCBI chr19:9,825,114...9,920,371
Ensembl chr19:9,886,693...9,920,451 		JBrowse link
G Plekha7 pleckstrin homology domain containing A7 involved_in ISO
IBA		 (PMID:19041755)
GO_REF:0000033		 RGD
GO_Central		 PMID:19041755 GO_REF:0000033 NCBI chr 1:170,364,524...170,547,843
Ensembl chr 1:170,365,135...170,547,775 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18195
      cellular component organization or biogenesis 6958
        cellular component organization 6699
          cell junction organization 970
            cell-cell junction organization 239
              adherens junction organization 58
                adherens junction assembly + 13
                adherens junction disassembly 1
                adherens junction maintenance + 9
                negative regulation of adherens junction organization 3
                positive regulation of adherens junction organization 2
                regulation of adherens junction organization + 5
paths to the root