Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | genetic disease | | ISO | AFDN (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | | |
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Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | genetic disease | | ISO | AFDN (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | | |
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# | Reference Title | Reference Citation |
1. | ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions. | Asada M, etal., J Biol Chem 2003 Feb 7;278(6):4103-11. |
2. | Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1. | Ebnet K, etal., J Biol Chem. 2000 Sep 8;275(36):27979-88. |
3. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
4. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
5. | AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease. | Haskin J, etal., Hum Mol Genet. 2013 May 15;22(10):2083-96. doi: 10.1093/hmg/ddt058. Epub 2013 Feb 7. |
6. | nArgBP2, a novel neural member of ponsin/ArgBP2/vinexin family that interacts with synapse-associated protein 90/postsynaptic density-95-associated protein (SAPAP). | Kawabe H, etal., J Biol Chem 1999 Oct 22;274(43):30914-8. |
7. | Binding between the junctional proteins afadin and PLEKHA7 and implication in the formation of adherens junction in epithelial cells. | Kurita S, etal., J Biol Chem. 2013 Oct 11;288(41):29356-68. doi: 10.1074/jbc.M113.453464. Epub 2013 Aug 29. |
8. | Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer. | Letessier A, etal., Oncogene. 2007 Jan 11;26(2):298-307. doi: 10.1038/sj.onc.1209772. Epub 2006 Jul 3. |
9. | Temporal and spatial localization of nectin-1 and l-afadin during synaptogenesis in hippocampal neurons. | Lim ST, etal., J Comp Neurol. 2008 Mar 10;507(2):1228-44. |
10. | Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction. | Mandai K, etal., J Cell Biol 1997 Oct 20;139(2):517-28. |
11. | s-Afadin binds to MAGUIN/Cnksr2 and regulates the localization of the AMPA receptor and glutamatergic synaptic response in hippocampal neurons. | Maruo T, etal., J Biol Chem. 2023 Apr;299(4):103040. doi: 10.1016/j.jbc.2023.103040. Epub 2023 Feb 18. |
12. | Spermine increases arginase activity in the liver after carbon tetrachloride-induced hepatic injury in Long-Evans rats. | Mendez JD, etal., Biomed Pharmacother. 2006 Feb;60(2):82-5. Epub 2005 Dec 27. |
13. | Purification and molecular cloning of succinyltransferase of the rat alpha-ketoglutarate dehydrogenase complex. Absence of a sequence motif of the putative E3 and/or E1 binding site. | Nakano K, etal., J Biol Chem 1991 Oct 5;266(28):19013-7. |
14. | Involvement of LMO7 in the association of two cell-cell adhesion molecules, nectin and E-cadherin, through afadin and alpha-actinin in epithelial cells. | Ooshio T, etal., J Biol Chem 2004 Jul 23;279(30):31365-73. Epub 2004 May 12. |
15. | PID Annotation Import Pipeline | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
16. | Drebrin preserves endothelial integrity by stabilizing nectin at adherens junctions. | Rehm K, etal., J Cell Sci. 2013 Aug 15;126(Pt 16):3756-69. doi: 10.1242/jcs.129437. Epub 2013 Jun 7. |
17. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
18. | Afadin is required for maintenance of dendritic structure and excitatory tone. | Srivastava DP, etal., J Biol Chem. 2012 Oct 19;287(43):35964-74. doi: 10.1074/jbc.M112.363358. Epub 2012 Sep 4. |
19. | Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteins. | Tachibana K, etal., J Cell Biol. 2000 Sep 4;150(5):1161-76. |
PMID:8889548 | PMID:9707552 | PMID:10225955 | PMID:10704870 | PMID:11731229 | PMID:12203721 | PMID:12515806 | PMID:15489334 | PMID:15509704 | PMID:15728677 | PMID:16301177 | PMID:16396499 |
PMID:16641100 | PMID:16882694 | PMID:17013812 | PMID:18604197 | PMID:19461049 | PMID:21478912 | PMID:22027834 | PMID:22512338 | PMID:23885123 | PMID:24567331 | PMID:25100583 | PMID:25468996 |
PMID:25808489 | PMID:25893857 | PMID:27815408 | PMID:30268521 | PMID:30463011 | PMID:30572094 | PMID:32357304 |
Afdn (Rattus norvegicus - Norway rat) |
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AFDN (Homo sapiens - human) |
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Afdn (Mus musculus - house mouse) |
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Afdn (Chinchilla lanigera - long-tailed chinchilla) |
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AFDN (Pan paniscus - bonobo/pygmy chimpanzee) |
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AFDN (Canis lupus familiaris - dog) |
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Afdn (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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AFDN (Sus scrofa - pig) |
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AFDN (Chlorocebus sabaeus - green monkey) |
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Afdn (Heterocephalus glaber - naked mole-rat) |
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Variants in Afdn
513 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH129150 |
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RH129198 |
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RH143433 |
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RH143971 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 40 | 34 | 24 | 10 | 24 | 6 | 6 | 74 | 35 | 41 | 11 | 6 |
Low | 3 | 23 | 17 | 9 | 17 | 2 | 5 | 2 | |||||
Below cutoff |
RefSeq Transcripts | NM_013217 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_063282455 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282461 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282468 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282472 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282476 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282479 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282481 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282491 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282492 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282494 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282497 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282501 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282503 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282505 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282507 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282509 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282513 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282518 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282519 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282523 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282526 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282529 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282534 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282537 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282539 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282542 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282545 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282551 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282554 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282558 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282559 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282560 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282561 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282563 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282565 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282572 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282574 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AA963026 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
CA511204 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CK476731 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CN542111 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
EV767501 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000001 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
U83230 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
U83231 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000032667 ⟹ ENSRNOP00000029044 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000096238 ⟹ ENSRNOP00000079686 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000096510 ⟹ ENSRNOP00000094008 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000106034 ⟹ ENSRNOP00000088861 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000107704 ⟹ ENSRNOP00000078878 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_013217 ⟹ NP_037349 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_063282455 ⟹ XP_063138525 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282461 ⟹ XP_063138531 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282468 ⟹ XP_063138538 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282472 ⟹ XP_063138542 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282476 ⟹ XP_063138546 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282479 ⟹ XP_063138549 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282481 ⟹ XP_063138551 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282491 ⟹ XP_063138561 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282492 ⟹ XP_063138562 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282494 ⟹ XP_063138564 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282497 ⟹ XP_063138567 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282501 ⟹ XP_063138571 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282503 ⟹ XP_063138573 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282505 ⟹ XP_063138575 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282507 ⟹ XP_063138577 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282509 ⟹ XP_063138579 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282513 ⟹ XP_063138583 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282518 ⟹ XP_063138588 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282519 ⟹ XP_063138589 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282523 ⟹ XP_063138593 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282526 ⟹ XP_063138596 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282529 ⟹ XP_063138599 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282534 ⟹ XP_063138604 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282537 ⟹ XP_063138607 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282539 ⟹ XP_063138609 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282542 ⟹ XP_063138612 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282545 ⟹ XP_063138615 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282551 ⟹ XP_063138621 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282554 ⟹ XP_063138624 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282558 ⟹ XP_063138628 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282559 ⟹ XP_063138629 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282560 ⟹ XP_063138630 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282561 ⟹ XP_063138631 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282563 ⟹ XP_063138633 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282565 ⟹ XP_063138635 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282572 ⟹ XP_063138642 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282574 ⟹ XP_063138644 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_037349 | (Get FASTA) | NCBI Sequence Viewer |
XP_063138525 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138531 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138538 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138542 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138546 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138549 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138551 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138561 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138562 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138564 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138567 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138571 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138573 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138575 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138577 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138579 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138583 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138588 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138589 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138593 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138596 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138599 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138604 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138607 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138609 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138612 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138615 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138621 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138624 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138628 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138629 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138630 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138631 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138633 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138635 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138642 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138644 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAC53390 | (Get FASTA) | NCBI Sequence Viewer |
AAC53391 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000029044.7 | ||
ENSRNOP00000078878.1 | |||
ENSRNOP00000079686.1 | |||
ENSRNOP00000088861 | |||
ENSRNOP00000088861.1 | |||
ENSRNOP00000094008.1 | |||
ENSRNOP00060001274 | |||
ENSRNOP00065020446 | |||
GenBank Protein | O35889 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_037349 ⟸ NM_013217 |
- UniProtKB: | O35890 (UniProtKB/Swiss-Prot), O35889 (UniProtKB/Swiss-Prot), A6KS86 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000029044 ⟸ ENSRNOT00000032667 |
RefSeq Acc Id: | ENSRNOP00000079686 ⟸ ENSRNOT00000096238 |
RefSeq Acc Id: | ENSRNOP00000078878 ⟸ ENSRNOT00000107704 |
RefSeq Acc Id: | ENSRNOP00000088861 ⟸ ENSRNOT00000106034 |
RefSeq Acc Id: | ENSRNOP00000094008 ⟸ ENSRNOT00000096510 |
RefSeq Acc Id: | XP_063138546 ⟸ XM_063282476 |
- Peptide Label: | isoform X5 |
RefSeq Acc Id: | XP_063138551 ⟸ XM_063282481 |
- Peptide Label: | isoform X7 |
RefSeq Acc Id: | XP_063138525 ⟸ XM_063282455 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063138564 ⟸ XM_063282494 |
- Peptide Label: | isoform X10 |
RefSeq Acc Id: | XP_063138531 ⟸ XM_063282461 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_063138538 ⟸ XM_063282468 |
- Peptide Label: | isoform X3 |
RefSeq Acc Id: | XP_063138542 ⟸ XM_063282472 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_063138567 ⟸ XM_063282497 |
- Peptide Label: | isoform X11 |
RefSeq Acc Id: | XP_063138579 ⟸ XM_063282509 |
- Peptide Label: | isoform X16 |
RefSeq Acc Id: | XP_063138573 ⟸ XM_063282503 |
- Peptide Label: | isoform X13 |
RefSeq Acc Id: | XP_063138583 ⟸ XM_063282513 |
- Peptide Label: | isoform X17 |
RefSeq Acc Id: | XP_063138575 ⟸ XM_063282505 |
- Peptide Label: | isoform X14 |
RefSeq Acc Id: | XP_063138588 ⟸ XM_063282518 |
- Peptide Label: | isoform X18 |
RefSeq Acc Id: | XP_063138633 ⟸ XM_063282563 |
- Peptide Label: | isoform X34 |
RefSeq Acc Id: | XP_063138631 ⟸ XM_063282561 |
- Peptide Label: | isoform X33 |
RefSeq Acc Id: | XP_063138549 ⟸ XM_063282479 |
- Peptide Label: | isoform X6 |
RefSeq Acc Id: | XP_063138577 ⟸ XM_063282507 |
- Peptide Label: | isoform X15 |
RefSeq Acc Id: | XP_063138561 ⟸ XM_063282491 |
- Peptide Label: | isoform X8 |
RefSeq Acc Id: | XP_063138596 ⟸ XM_063282526 |
- Peptide Label: | isoform X21 |
RefSeq Acc Id: | XP_063138599 ⟸ XM_063282529 |
- Peptide Label: | isoform X22 |
RefSeq Acc Id: | XP_063138562 ⟸ XM_063282492 |
- Peptide Label: | isoform X9 |
RefSeq Acc Id: | XP_063138589 ⟸ XM_063282519 |
- Peptide Label: | isoform X19 |
RefSeq Acc Id: | XP_063138635 ⟸ XM_063282565 |
- Peptide Label: | isoform X35 |
RefSeq Acc Id: | XP_063138644 ⟸ XM_063282574 |
- Peptide Label: | isoform X37 |
RefSeq Acc Id: | XP_063138607 ⟸ XM_063282537 |
- Peptide Label: | isoform X24 |
RefSeq Acc Id: | XP_063138604 ⟸ XM_063282534 |
- Peptide Label: | isoform X23 |
RefSeq Acc Id: | XP_063138571 ⟸ XM_063282501 |
- Peptide Label: | isoform X12 |
RefSeq Acc Id: | XP_063138609 ⟸ XM_063282539 |
- Peptide Label: | isoform X25 |
RefSeq Acc Id: | XP_063138612 ⟸ XM_063282542 |
- Peptide Label: | isoform X26 |
RefSeq Acc Id: | XP_063138621 ⟸ XM_063282551 |
- Peptide Label: | isoform X28 |
RefSeq Acc Id: | XP_063138628 ⟸ XM_063282558 |
- Peptide Label: | isoform X30 |
RefSeq Acc Id: | XP_063138593 ⟸ XM_063282523 |
- Peptide Label: | isoform X20 |
- UniProtKB: | A0A8I5ZLU6 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063138615 ⟸ XM_063282545 |
- Peptide Label: | isoform X27 |
RefSeq Acc Id: | XP_063138624 ⟸ XM_063282554 |
- Peptide Label: | isoform X29 |
RefSeq Acc Id: | XP_063138629 ⟸ XM_063282559 |
- Peptide Label: | isoform X31 |
RefSeq Acc Id: | XP_063138630 ⟸ XM_063282560 |
- Peptide Label: | isoform X32 |
RefSeq Acc Id: | XP_063138642 ⟸ XM_063282572 |
- Peptide Label: | isoform X36 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-O35889-F1-model_v2 | AlphaFold | O35889 | 1-1829 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:708561 | AgrOrtholog |
BioCyc Gene | G2FUF-61408 | BioCyc |
Ensembl Genes | ENSRNOG00000023753 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
ENSRNOG00060001313 | UniProtKB/Swiss-Prot | |
ENSRNOG00065015321 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000032667.8 | UniProtKB/TrEMBL |
ENSRNOT00000096238.1 | UniProtKB/TrEMBL | |
ENSRNOT00000096510.1 | UniProtKB/TrEMBL | |
ENSRNOT00000106034 | ENTREZGENE | |
ENSRNOT00000106034.1 | UniProtKB/Swiss-Prot | |
ENSRNOT00000107704.1 | UniProtKB/TrEMBL | |
ENSRNOT00060002078 | UniProtKB/Swiss-Prot | |
ENSRNOT00065025971 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 2.30.42.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
2.60.200.20 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
InterPro | Afadin | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
CBD_Afadin | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Dilute_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
FHA_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PDZ | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PDZ_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RA_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SMAD_FHA_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Ubiquitin-like_domsf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:26955 | UniProtKB/Swiss-Prot |
NCBI Gene | 26955 | ENTREZGENE |
PANTHER | AFADIN | UniProtKB/Swiss-Prot |
AFADIN | UniProtKB/Swiss-Prot | |
AFADIN | UniProtKB/TrEMBL | |
AFADIN | UniProtKB/TrEMBL | |
Pfam | DIL | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
FHA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PDZ | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PF00788 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Afdn | PhenoGen |
PROSITE | DILUTE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PDZ | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PS50200 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000023753 | RatGTEx |
ENSRNOG00060001313 | RatGTEx | |
ENSRNOG00065015321 | RatGTEx | |
SMART | DIL | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
FHA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PDZ | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SM00314 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Superfamily-SCOP | SSF49879 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SSF50156 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SSF54236 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UniProt | A0A8I5ZLU6 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I5ZNL2_RAT | UniProtKB/TrEMBL | |
A0A8I6AL62_RAT | UniProtKB/TrEMBL | |
A6KS86 | ENTREZGENE, UniProtKB/TrEMBL | |
AFAD_RAT | UniProtKB/Swiss-Prot | |
F1LT10_RAT | UniProtKB/TrEMBL | |
O35889 | ENTREZGENE | |
O35890 | ENTREZGENE | |
UniProt Secondary | O35890 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2016-07-05 | Afdn | afadin, adherens junction formation factor | Mllt4 | myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2015-07-01 | Mllt4 | myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 | Mllt4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-03-19 | Mllt4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | Mllt4 | myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog (Drosophila) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-02-26 | Mllt4 | myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog (Drosophila) | Af6 | afadin | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-10-07 | Af6 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |