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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Brevetoxin B
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Accession:CHEBI:80770 term browser browse the term
Definition:A ciguatoxin that has formula C50H70O14.
Synonyms:related_synonym: Formula=C50H70O14;   InChI=1S/C50H70O14/c1-25(24-51)14-28-17-37(52)50(8)41(54-28)19-33-34(61-50)18-32-29(55-33)10-9-12-46(4)42(58-32)23-49(7)40(62-46)21-39-47(5,64-49)13-11-30-44(60-39)26(2)15-31-36(56-30)22-48(6)38(57-31)20-35-45(63-48)27(3)16-43(53)59-35/h9-10,16,24,26,28-42,44-45,52H,1,11-15,17-23H2,2-8H3/b10-9-/t26-,28-,29-,30+,31+,32+,33+,34-,35+,36-,37+,38-,39+,40-,41-,42-,44-,45-,46+,47-,48+,49+,50+/m1/s1;   InChIKey=LYTCVQQGCSNFJU-FGRVLNGBSA-N;   SMILES=C[C@@H]1C[C@@H]2O[C@@H]3C[C@@H]4OC(=O)C=C(C)[C@H]4O[C@@]3(C)C[C@H]2O[C@H]2CC[C@@]3(C)O[C@@]4(C)C[C@H]5O[C@H]6C[C@H]7O[C@@]8(C)[C@@H](O)C[C@@H](CC(=C)C=O)O[C@@H]8C[C@@H]7O[C@@H]6\\C=C/C[C@]5(C)O[C@@H]4C[C@@H]3O[C@H]12
 alt_id: MESH:C546611
 xref: CAS:79580-28-2;   KEGG:C16857
 xref_mesh: MESH:C043466


show annotations for term's descendants           Sort by:
Brevetoxin B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin multiple interactions ISO brevetoxin B binds to and results in increased metabolism of ALB protein CTD PMID:21142195 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Ankrd17 ankyrin repeat domain 17 decreases expression ISO brevetoxin 2 results in decreased expression of ANKRD17 mRNA CTD PMID:20498034 NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617 		JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO brevetoxin 2 results in increased expression of ATM mRNA CTD PMID:20498034 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atrx ATRX, chromatin remodeler decreases expression ISO brevetoxin 2 results in decreased expression of ATRX mRNA CTD PMID:20498034 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO brevetoxin 2 results in increased expression of BAG3 mRNA CTD PMID:20498034 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bcl2l10 Bcl2-like 10 increases expression ISO brevetoxin 2 results in increased expression of BCL2L10 mRNA CTD PMID:20498034 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO brevetoxin 2 results in increased expression of BCL2L11 mRNA CTD PMID:20498034 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO brevetoxin 2 results in decreased expression of BCLAF1 mRNA CTD PMID:20498034 NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832 		JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 increases expression ISO brevetoxin 2 results in increased expression of BIRC6 mRNA CTD PMID:20498034 NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434 		JBrowse link
G Bmp7 bone morphogenetic protein 7 increases expression ISO brevetoxin 2 results in increased expression of BMP7 mRNA CTD PMID:20498034 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Bnip2 BCL2 interacting protein 2 decreases expression ISO brevetoxin 2 results in decreased expression of BNIP2 mRNA CTD PMID:20498034 NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like decreases expression ISO brevetoxin 2 results in decreased expression of BNIP3L mRNA CTD PMID:20498034 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO brevetoxin 2 results in increased expression of BTG2 mRNA CTD PMID:20498034 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Card6 caspase recruitment domain family, member 6 increases expression ISO brevetoxin 2 results in increased expression of CARD6 mRNA CTD PMID:20498034 NCBI chr 2:54,194,343...54,206,902
Ensembl chr 2:54,195,739...54,206,846 		JBrowse link
G Casp8 caspase 8 increases activity ISO brevetoxin 2 results in increased activity of CASP8 protein CTD PMID:19536525 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO brevetoxin 2 results in increased expression of CHEK1 mRNA CTD PMID:20498034 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO brevetoxin 2 results in increased expression of CHEK2 mRNA CTD PMID:20498034 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression ISO brevetoxin 2 results in decreased expression of DAPK1 mRNA CTD PMID:20498034 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO brevetoxin 2 results in increased expression of DDIT3 mRNA CTD PMID:20498034 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Fancg FA complementation group G increases expression ISO brevetoxin 2 results in increased expression of FANCG mRNA CTD PMID:20498034 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO brevetoxin 2 results in increased expression of GADD45G mRNA CTD PMID:20498034 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO brevetoxin 2 results in increased expression of GDF9 mRNA CTD PMID:20498034 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672 		JBrowse link
G Il12b interleukin 12B increases expression ISO brevetoxin 2 results in increased expression of IL12B mRNA CTD PMID:20498034 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il13 interleukin 13 increases expression ISO brevetoxin 2 results in increased expression of IL13 mRNA CTD PMID:20498034 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il16 interleukin 16 increases expression ISO brevetoxin 2 results in increased expression of IL16 mRNA CTD PMID:20498034 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130 		JBrowse link
G Il17c interleukin 17C increases expression ISO brevetoxin 2 results in increased expression of IL17C mRNA CTD PMID:20498034 NCBI chr19:50,484,890...50,486,169
Ensembl chr19:50,484,890...50,486,169 		JBrowse link
G Il19 interleukin 19 increases expression ISO brevetoxin 2 results in increased expression of IL19 mRNA CTD PMID:20498034 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Il21 interleukin 21 increases expression ISO brevetoxin 2 results in increased expression of IL21 mRNA CTD PMID:20498034 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Il24 interleukin 24 increases expression ISO brevetoxin 2 results in increased expression of IL24 mRNA CTD PMID:20498034 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il36g interleukin 36, gamma increases expression ISO brevetoxin 2 results in increased expression of IL36G mRNA CTD PMID:20498034 NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480 		JBrowse link
G Il4 interleukin 4 increases expression ISO brevetoxin 2 results in increased expression of IL4 mRNA CTD PMID:20498034 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 increases expression ISO brevetoxin 2 results in increased expression of IL6 mRNA CTD PMID:20549194 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il9 interleukin 9 increases expression ISO brevetoxin 2 results in increased expression of IL9 mRNA CTD PMID:20498034 NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895 		JBrowse link
G Lig1 DNA ligase 1 increases expression ISO brevetoxin 2 results in increased expression of LIG1 mRNA CTD PMID:20498034 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 increases expression ISO brevetoxin 2 results in increased expression of NAIP mRNA CTD PMID:20498034 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542 		JBrowse link
G Nol3 nucleolar protein 3 increases expression ISO brevetoxin 2 results in increased expression of NOL3 mRNA CTD PMID:20498034 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Pcbp4 poly(rC) binding protein 4 increases expression ISO brevetoxin 2 results in increased expression of PCBP4 mRNA CTD PMID:20498034 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase increases expression ISO brevetoxin 2 results in increased expression of PNKP mRNA CTD PMID:20498034 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO brevetoxin 2 results in increased expression of PPP1R15A mRNA CTD PMID:20498034 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Pycard PYD and CARD domain containing increases expression ISO brevetoxin 2 results in increased expression of PYCARD mRNA CTD PMID:20498034 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase increases expression ISO brevetoxin 2 results in increased expression of RAD18 mRNA CTD PMID:20498034 NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069 		JBrowse link
G Rad21 RAD21 cohesin complex component decreases expression ISO brevetoxin 2 results in decreased expression of RAD21 mRNA CTD PMID:20498034 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817 		JBrowse link
G Rad50 RAD50 double strand break repair protein increases expression ISO brevetoxin 2 results in increased expression of RAD50 mRNA CTD PMID:20498034 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease decreases expression ISO brevetoxin 2 results in decreased expression of RBBP8 mRNA CTD PMID:20498034 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO brevetoxin 2 results in increased expression of TGFB2 mRNA CTD PMID:20498034 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression ISO brevetoxin 2 results in increased expression of TGFB3 mRNA CTD PMID:20498034 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO brevetoxin 2 results in increased expression of TNF mRNA CTD PMID:20498034 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO brevetoxin 2 results in increased expression of TNFRSF10A mRNA CTD PMID:20498034 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467 		JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO brevetoxin 2 results in increased expression of TNFRSF25 mRNA CTD PMID:20498034 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341 		JBrowse link
G Tnfsf12 TNF superfamily member 12 increases expression ISO brevetoxin 2 results in increased expression of TNFSF12 mRNA CTD PMID:20498034 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213 		JBrowse link
G Tnfsf8 TNF superfamily member 8 increases expression ISO brevetoxin 2 results in increased expression of TNFSF8 mRNA CTD PMID:20498034 NCBI chr 5:77,250,942...77,277,364
Ensembl chr 5:77,251,373...77,277,421 		JBrowse link
G Tp73 tumor protein p73 increases expression ISO brevetoxin 2 results in increased expression of TP73 mRNA CTD PMID:20498034 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Trex1 three prime repair exonuclease 1 increases expression ISO brevetoxin 2 results in increased expression of TREX1 mRNA CTD PMID:20498034 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Xrcc2 X-ray repair cross complementing 2 increases expression ISO brevetoxin 2 results in increased expression of XRCC2 mRNA CTD PMID:20498034 NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 increases expression ISO brevetoxin 2 results in increased expression of XRCC3 mRNA CTD PMID:20498034 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    role 19810
      biological role 19808
        poison 18610
          toxin 15979
            ciguatoxin 1039
              Brevetoxin B 55
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19731
                        carbon atom 19727
                          organic molecular entity 19727
                            heteroorganic entity 19484
                              organochalcogen compound 19248
                                organooxygen compound 19165
                                  ether 17280
                                    cyclic ether 11761
                                      polycyclic ether 1425
                                        ciguatoxin 1039
                                          Brevetoxin B 55
paths to the root