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creatine - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:creatine
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Accession:CHEBI:16919 term browser browse the term
Definition:A glycine derivative having methyl and amidino groups attached to the nitrogen.
Synonyms:exact_synonym: N-[amino(imino)methyl]-N-methylglycine
 related_synonym: ((amino(imino)methyl)(methyl)amino)acetic acid;   (N-methylcarbamimidamido)acetic acid;   (alpha-methylguanido)acetic acid;   Creatin;   Formula=C4H9N3O2;   InChI=1S/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H3,5,6)(H,8,9);   InChIKey=CVSVTCORWBXHQV-UHFFFAOYSA-N;   Kreatin;   Methylglycocyamine;   N-(aminoiminomethyl)-N-methylglycine;   N-[(E)-AMINO(IMINO)METHYL]-N-METHYLGLYCINE;   N-amidinosarcosine;   N-carbamimidoyl-N-methylglycine;   N-methyl-N-guanylglycine;   SMILES=CN(CC(O)=O)C(N)=N;   alpha-Methylguanidino acetic acid
 alt_id: CHEBI:14028;   CHEBI:23404;   CHEBI:3909;   CHEBI:41678
 xref: CAS:57-00-1;   Chemspider:566;   DrugBank:DB00148;   Drug_Central:4661;   Gmelin:240513;   HMDB:HMDB0000064;   KEGG:C00300
 xref_mesh: MESH:D003401
 xref: MetaCyc:CREATINE;   PDBeChem:CRN;   PMID:11356982;   PMID:11483809;   PMID:11867929;   PMID:12085493;   PMID:12184144;   PMID:12878267;   PMID:16445883;   PMID:17190852;   PMID:17253521;   PMID:17416441;   PMID:18555535;   PMID:19082141;   PMID:19651674;   PMID:19741514;   PMID:19968328;   PMID:21556832;   PMID:21660517;   PMID:21698493;   PMID:22038587;   PMID:22101931;   PMID:22196490;   PMID:22252611;   PMID:22347384;   PMID:22386973;   PMID:22422801;   PMID:22429992;   PMID:22465051;   PMID:22521466;   PMID:7752905;   Reaxys:907175;   Wikipedia:Creatine
 cyclic_relationship: is_conjugate_acid_of CHEBI:66924;   is_tautomer_of CHEBI:57947

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creatine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 multiple interactions ISO Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 4:177,262,848...177,386,837
Ensembl chr 4:175,532,547...175,655,356 		JBrowse link
G App amyloid beta precursor protein increases secretion ISO Creatine analog results in increased secretion of APP protein modified form CTD PMID:22906069 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression		 ISO Sirolimus inhibits the reaction [Creatine results in increased expression of BDNF protein] CTD PMID:33022268 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Creatine co-treated with Ribose] results in decreased activity of CASP3 protein CTD PMID:21220914 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatine; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatine]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatine]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatine] CTD PMID:24709313 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO [CSF3 protein co-treated with Paclitaxel] results in decreased abundance of Creatine CTD PMID:9018096 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Dek DEK proto-oncogene increases chemical synthesis ISO DEK protein results in increased chemical synthesis of Creatine CTD PMID:28558019 NCBI chr17:17,786,989...17,809,096
Ensembl chr17:17,580,843...17,602,808 		JBrowse link
G Gatm glycine amidinotransferase increases chemical synthesis ISO GATM protein results in increased chemical synthesis of Creatine CTD PMID:16820567 NCBI chr 3:130,112,508...130,137,664
Ensembl chr 3:109,658,951...109,684,129 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:96,591,049...96,594,082 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation
multiple interactions		 ISO Creatine results in increased phosphorylation of MTOR protein
Sirolimus inhibits the reaction [Creatine results in increased phosphorylation of MTOR protein]		 CTD PMID:33022268 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Creatine results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Snca synuclein alpha multiple interactions ISO [coenzyme Q10 co-treated with Creatine] results in decreased expression of SNCA protein CTD PMID:19476553 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
creatinine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 increases abundance ISO BMAL1 gene mutant form results in increased abundance of Creatinine CTD PMID:27056296 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine] CTD PMID:24709313 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance		 ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Creatinine] CTD PMID:27469509 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Lepr leptin receptor affects abundance
multiple interactions
increases abundance		 ISO LEPR affects the abundance of Creatinine
Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Creatinine]; swietenine inhibits the reaction [LEPR gene mutant form results in increased abundance of Creatinine]		 CTD PMID:20567778 PMID:29988851 PMID:36066211 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [NFE2L2 protein affects the susceptibility to ochratoxin A] which results in increased abundance of Creatinine CTD PMID:28710020 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [SC 560 results in decreased activity of PTGS1 protein] which results in increased abundance of Creatinine CTD PMID:19629487 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Creatinine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Creatinine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,490,262...46,532,954
Ensembl chr10:45,991,095...46,033,904 		JBrowse link
G Sod2 superoxide dismutase 2 decreases abundance ISO SOD2 protein results in decreased abundance of Creatinine CTD PMID:19917352 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
N-phosphocreatine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]]; Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein] CTD PMID:37648050 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO		 Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of BAX protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of BAX protein]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]		 CTD PMID:34358621 PMID:34455488 PMID:37597758 PMID:37648050 PMID:39043266 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
decreases expression		 EXP Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of BBC3 mRNA]; Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of BBC3 protein]
Phosphocreatine results in decreased expression of BBC3 mRNA; Phosphocreatine results in decreased expression of BBC3 protein		 CTD PMID:37597758 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO		 Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased expression of BCL2 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]		 CTD PMID:34455488 PMID:37648050 PMID:39043266 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO		 7-oxozeanol inhibits the reaction [Phosphocreatine inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]; Phosphocreatine inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased expression of CASP3 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of CASP3 protein modified form]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 protein]		 CTD PMID:34358621 PMID:34455488 PMID:37597758 PMID:37648050 PMID:39043266 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions EXP
ISO		 Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased expression of CASP9 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP9 protein]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP9 protein]		 CTD PMID:34455488 PMID:37648050 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions EXP Phosphocreatine promotes the reaction [Doxorubicin results in decreased expression of CTGF mRNA] CTD PMID:37597758 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ctnnd1 catenin delta 1 multiple interactions EXP Phosphocreatine promotes the reaction [Doxorubicin results in decreased expression of CTNND1 mRNA] CTD PMID:37597758 NCBI chr 3:90,090,025...90,141,247
Ensembl chr 3:69,683,313...69,734,516 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin affects the localization of CYCS protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of CYCS protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CYCS protein] CTD PMID:34455488 PMID:39043266 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of FOXO3 protein] CTD PMID:34358621 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased phosphorylation of GSK3B protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] CTD PMID:34455488 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions EXP Phosphocreatine promotes the reaction [Doxorubicin results in decreased expression of IGF1R mRNA] CTD PMID:37597758 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased secretion of INS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein] CTD PMID:34455488 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions EXP Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of IRS1 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased phosphorylation of IRS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of IRS1 protein] CTD PMID:34455488 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP Phosphocreatine inhibits the reaction [Dietary Fats results in decreased activity of LPL protein] CTD PMID:37648050 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 multiple interactions EXP 7-oxozeanol inhibits the reaction [Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of MAP3K7 protein]]; Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of MAP3K7 protein]; Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of MAP3K7 protein] CTD PMID:34358621 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 decreases expression
multiple interactions		 EXP Phosphocreatine results in decreased expression of MAPK7 mRNA
Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of MAPK7 mRNA]		 CTD PMID:37597758 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Mapt microtubule-associated protein tau decreases abundance
multiple interactions		 ISO MAPT protein mutant form results in decreased abundance of Phosphocreatine
PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Phosphocreatine]		 CTD PMID:39172838 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mir143 microRNA 143 multiple interactions
increases expression		 EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of MIR143 mRNA]
Phosphocreatine results in increased expression of MIR143 mRNA		 CTD PMID:37597758 NCBI chr18:57,371,349...57,371,453
Ensembl chr18:55,101,006...55,101,110 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Phosphocreatine affects the reaction [Doxorubicin affects the expression of NFE2L2 protein]; Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 protein] CTD PMID:34358621 PMID:37597758 PMID:39043266 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha decreases expression
multiple interactions		 EXP Phosphocreatine results in decreased expression of PDGFRA mRNA
Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of PDGFRA mRNA]		 CTD PMID:37597758 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of PPARGC1A protein] CTD PMID:39043266 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions EXP Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of PPID protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of PPID protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of PPID protein] CTD PMID:34455488 NCBI chr 2:167,025,985...167,037,998
Ensembl chr 2:164,727,779...164,740,221 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 EXP Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of PTGS2 mRNA]
Phosphocreatine results in decreased expression of PTGS2 mRNA		 CTD PMID:37597758 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of RIPK3 protein] CTD PMID:34358621 NCBI chr15:33,253,071...33,262,025
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of SOD2 protein] CTD PMID:37597758 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of SOD3 protein] CTD PMID:34358621 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases response to substance
multiple interactions		 EXP STAT3 protein results in increased susceptibility to Phosphocreatine
Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of STAT3 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of STAT3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]		 CTD PMID:34455488 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      application 19697
        pharmaceutical 19534
          drug 19534
            nutraceutical 13745
              creatine 44
                N-phosphocreatine 28
                creatinine 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    main group molecular entity 19824
                      s-block molecular entity 19658
                        hydrogen molecular entity 19640
                          hydrides 19145
                            inorganic hydride 18162
                              pnictogen hydride 18152
                                nitrogen hydride 18059
                                  azane 17869
                                    ammonia 17868
                                      organic amino compound 17868
                                        amino acid 16061
                                          alpha-amino acid 13936
                                            serine family amino acid 5765
                                              glycine 3329
                                                glycine derivative 3317
                                                  creatine 44
                                                    N-phosphocreatine 28
                                                    creatinine 9
paths to the root