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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of pattern recognition receptor signaling pathway
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Accession:GO:0062207 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway.

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negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifi16 interferon gamma inducible protein 16 involved_in ISO (PMID:30104205) UniProt PMID:30104205 NCBI chrNW_004955468:10,828,726...10,845,853 JBrowse link
G Trim11 tripartite motif containing 11 involved_in ISO (PMID:27498865) UniProt PMID:27498865 NCBI chrNW_004955581:114,750...123,410
Ensembl chrNW_004955581:114,750...125,143 		JBrowse link
negative regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars2 alanyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:39322678) UniProt PMID:39322678 NCBI chrNW_004955437:9,915,371...9,924,886
Ensembl chrNW_004955437:9,913,867...9,924,886 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:26440888) UniProt PMID:26440888 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904 		JBrowse link
G Aurkb aurora kinase B involved_in ISO (PMID:33542149) UniProt PMID:33542149 NCBI chrNW_004955467:8,715,387...8,720,889
Ensembl chrNW_004955467:8,715,136...8,723,932 		JBrowse link
G Banf1 barrier to autointegration nuclear assembly factor 1 involved_in ISO (PMID:32792394) UniProt PMID:32792394 NCBI chrNW_004955422:19,337,038...19,338,824
Ensembl chrNW_004955422:19,337,038...19,338,824 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:32911482), (PMID:32912999) UniProt PMID:32911482 PMID:32912999 NCBI chrNW_004955493:8,593,104...8,607,297 JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:32715615) UniProt PMID:32715615 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Lyplal1 lysophospholipase like 1 involved_in ISO (PMID:37802025) UniProt PMID:37802025 NCBI chrNW_004955520:4,251,863...4,281,775
Ensembl chrNW_004955520:4,251,957...4,281,838 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:35460603) UniProt PMID:35460603 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 involved_in ISO (PMID:35322803) UniProt PMID:35322803 NCBI chrNW_004955458:747,770...773,885
Ensembl chrNW_004955458:750,226...773,483 		JBrowse link
G Ppp6c protein phosphatase 6 catalytic subunit involved_in ISO (PMID:32474700) UniProt PMID:32474700 NCBI chrNW_004955419:3,096,882...3,133,590
Ensembl chrNW_004955419:3,096,240...3,134,215 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:33273464) UniProt PMID:33273464 NCBI chrNW_004955454:7,733,697...7,890,896
Ensembl chrNW_004955454:7,733,978...7,890,867 		JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase acid like 3A involved_in ISO (PMID:37890481) UniProt PMID:37890481 NCBI chrNW_004955436:4,655,730...4,663,993
Ensembl chrNW_004955436:4,655,732...4,663,638 		JBrowse link
G Spsb3 splA/ryanodine receptor domain and SOCS box containing 3 involved_in ISO (PMID:38418882) UniProt PMID:38418882 NCBI chrNW_004955442:15,486,845...15,493,422
Ensembl chrNW_004955442:15,487,475...15,493,422 		JBrowse link
G Trex1 three prime repair exonuclease 1 involved_in ISO (PMID:33476576) UniProt PMID:33476576 NCBI chrNW_004955532:533,877...535,767
Ensembl chrNW_004955532:533,877...535,767 		JBrowse link
G Zdhhc18 zinc finger DHHC-type palmitoyltransferase 18 involved_in ISO (PMID:35438208) UniProt PMID:35438208 NCBI chrNW_004955452:6,176,077...6,211,669
Ensembl chrNW_004955452:6,175,991...6,209,902 		JBrowse link
negative regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itch itchy E3 ubiquitin protein ligase involved_in ISO (PMID:27736772) UniProt PMID:27736772 NCBI chrNW_004955422:26,810,829...26,918,517
Ensembl chrNW_004955422:26,809,972...26,887,123 		JBrowse link
G Tarbp2 TARBP2 subunit of RISC loading complex involved_in ISO (PMID:30927622) UniProt PMID:30927622 NCBI chrNW_004955458:793,753...798,755
Ensembl chrNW_004955458:793,759...798,806 		JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO (PMID:27736772) UniProt PMID:27736772 NCBI chrNW_004955410:29,366,295...29,445,205
Ensembl chrNW_004955410:29,365,844...29,444,302 		JBrowse link
G Tspan6 tetraspanin 6 involved_in ISO (PMID:22908223) UniProt PMID:22908223 NCBI chrNW_004955503:6,782,264...6,788,533
Ensembl chrNW_004955503:6,779,377...6,789,142 		JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO (PMID:19164550) UniProt PMID:19164550 NCBI chrNW_004955467:10,788,142...10,792,272
Ensembl chrNW_004955467:10,788,277...10,792,449 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (PMID:21187438) UniProt PMID:21187438 NCBI chrNW_004955451:16,186,263...16,191,928
Ensembl chrNW_004955451:16,185,510...16,191,719 		JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:25865883) UniProt PMID:25865883 NCBI chrNW_004955402:11,649,160...11,670,010
Ensembl chrNW_004955402:11,648,849...11,672,545 		JBrowse link
G Tkfc triokinase and FMN cyclase involved_in ISO (PMID:17600090) UniProt PMID:17600090 NCBI chrNW_004955511:6,200,433...6,235,855
Ensembl chrNW_004955511:6,200,433...6,236,283 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300a molecule involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376 		JBrowse link
G Cd300lf CD300 molecule like family member f involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004955553:1,596,406...1,610,479
Ensembl chrNW_004955553:1,488,501...1,610,555 		JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17a abhydrolase domain containing 17A, depalmitoylase involved_in ISO (PMID:38092000) UniProt PMID:38092000 NCBI chrNW_004955495:6,159,314...6,167,429
Ensembl chrNW_004955495:6,159,314...6,168,123 		JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in ISO (PMID:29164996) UniProt PMID:29164996 NCBI chrNW_004955486:9,475,520...9,478,925
Ensembl chrNW_004955486:9,475,520...9,478,925 		JBrowse link
G Csnk1a1 casein kinase 1 alpha 1 involved_in ISO (PMID:34615873) UniProt PMID:34615873 NCBI chrNW_004955415:4,921,356...4,966,705
Ensembl chrNW_004955415:4,921,852...4,966,705 		JBrowse link
G Fbxl2 F-box and leucine rich repeat protein 2 involved_in ISO (PMID:26037928) UniProt PMID:26037928 NCBI chrNW_004955421:512,197...617,524
Ensembl chrNW_004955421:512,158...617,524 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISO (PMID:36586411) UniProt PMID:36586411 NCBI chrNW_004955412:23,863,513...23,867,984
Ensembl chrNW_004955412:23,862,590...23,867,984 		JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:30612879) UniProt PMID:30612879 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Lamp2 lysosomal associated membrane protein 2 involved_in ISO (PMID:36586411) UniProt PMID:36586411 NCBI chrNW_004955572:1,423,048...1,464,443
Ensembl chrNW_004955572:1,422,981...1,462,622 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISO (PMID:26347139) UniProt PMID:26347139 NCBI chrNW_004955442:14,068,436...14,093,889
Ensembl chrNW_004955442:14,068,348...14,094,016 		JBrowse link
G Nlrc3 NLR family CARD domain containing 3 involved_in ISO (PMID:25277106) UniProt PMID:25277106 NCBI chrNW_004955442:13,795,322...13,834,362
Ensembl chrNW_004955442:13,814,434...13,833,222 		JBrowse link
G Sirt2 sirtuin 2 acts_upstream_of_or_within ISO (PMID:23502856) MGI PMID:23502856 NCBI chrNW_004955468:626,365...644,441
Ensembl chrNW_004955468:626,365...644,441 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO (PMID:32514138)
(PMID:29887864)		 ARUK-UCL PMID:29887864 PMID:32514138 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
G Zdhhc12 zinc finger DHHC-type palmitoyltransferase 12 involved_in ISO (PMID:36586411) UniProt PMID:36586411 NCBI chrNW_004955570:1,131,234...1,133,909
Ensembl chrNW_004955570:1,131,234...1,133,909 		JBrowse link
negative regulation of non-canonical inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in ISO (PMID:37962578) UniProt PMID:37962578 NCBI chrNW_004955475:11,062,258...11,112,252
Ensembl chrNW_004955475:11,062,076...11,114,169 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:18342009) BHF-UCL PMID:18342009 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbin erbb2 interacting protein involved_in ISO (PMID:16203728) UniProt PMID:16203728 NCBI chrNW_004955446:3,046,268...3,151,796
Ensembl chrNW_004955446:3,049,258...3,151,796 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23991106) UniProt PMID:23991106 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:18342009) BHF-UCL PMID:18342009 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469 		JBrowse link
G Znrf4 zinc and ring finger 4 involved_in ISO (PMID:28656966) UniProt PMID:28656966 NCBI chrNW_004955495:3,854,178...3,855,556 JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO (PMID:19164550) UniProt PMID:19164550 NCBI chrNW_004955467:10,788,142...10,792,272
Ensembl chrNW_004955467:10,788,277...10,792,449 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (PMID:21187438)
(PMID:17475874)
(PMID:18411269)		 UniProt PMID:17475874 PMID:18411269 PMID:21187438 NCBI chrNW_004955451:16,186,263...16,191,928
Ensembl chrNW_004955451:16,185,510...16,191,719 		JBrowse link
G Gpatch3 G-patch domain containing 3 involved_in ISO (PMID:28414768) UniProt PMID:28414768 NCBI chrNW_004955452:6,234,241...6,241,949
Ensembl chrNW_004955452:6,234,241...6,241,991 		JBrowse link
G Nlrx1 NLR family member X1 acts_upstream_of_or_within ISO (PMID:21703540) MGI PMID:21703540 NCBI chrNW_004955412:20,275,767...20,287,414
Ensembl chrNW_004955412:20,275,917...20,287,414 		JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor involved_in ISO (PMID:26471729) UniProt PMID:26471729 NCBI chrNW_004955506:1,451,337...1,513,455
Ensembl chrNW_004955506:1,451,337...1,513,455 		JBrowse link
G Rnf125 ring finger protein 125 involved_in ISO (PMID:17460044), (PMID:26471729) UniProt PMID:17460044 PMID:26471729 NCBI chrNW_004955402:19,276,157...19,310,605
Ensembl chrNW_004955402:19,295,809...19,309,987 		JBrowse link
G Sec14l1 SEC14 like lipid binding 1 involved_in ISO (PMID:23843640) UniProt PMID:23843640 NCBI chrNW_004955506:5,159,090...5,231,827
Ensembl chrNW_004955506:5,158,805...5,232,551 		JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 involved_in ISO (PMID:26471729) UniProt PMID:26471729 NCBI chrNW_004955442:18,548,545...18,568,989
Ensembl chrNW_004955442:18,548,545...18,569,366 		JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) UniProt PMID:23609450 NCBI chrNW_004955404:30,254,934...30,266,898
Ensembl chrNW_004955404:30,254,841...30,270,921 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:20385881) UniProt PMID:20385881 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:26599367) UniProt PMID:26599367 NCBI chrNW_004955463:4,900,115...4,993,793
Ensembl chrNW_004955463:4,900,060...4,993,793 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15220916) MGI PMID:15220916 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chrNW_004955443:8,401,461...8,427,175
Ensembl chrNW_004955443:8,422,534...8,424,942 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) ARUK-UCL PMID:31134514 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) UniProt PMID:19865078 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:15474016) BHF-UCL PMID:15474016 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISO (PMID:21695056) CACAO PMID:21695056 NCBI chrNW_004955432:3,575,034...3,617,029
Ensembl chrNW_004955432:3,575,272...3,616,691 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) UniProt PMID:23609450 NCBI chrNW_004955404:30,254,934...30,266,898
Ensembl chrNW_004955404:30,254,841...30,270,921 		JBrowse link
G Bpifb1 BPI fold containing family B member 1 involved_in ISO (PMID:21900486) UniProt PMID:21900486 NCBI chrNW_004955422:27,955,298...27,976,051
Ensembl chrNW_004955422:27,950,918...27,975,146 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO (PMID:19948740) UniProt PMID:19948740 NCBI chrNW_004955419:6,229,437...6,416,619
Ensembl chrNW_004955419:6,228,591...6,416,402 		JBrowse link
G LOC102006100 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:19412184) UniProt PMID:19412184 NCBI chrNW_004955408:35,342,733...35,382,821
Ensembl chrNW_004955408:35,374,508...35,382,314 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:20385881) UniProt PMID:20385881 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28609714) UniProt PMID:28609714 NCBI chrNW_004955463:4,900,115...4,993,793
Ensembl chrNW_004955463:4,900,060...4,993,793 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1 group D member 1 involved_in ISO (PMID:18511497) BHF-UCL PMID:18511497 NCBI chrNW_004955451:14,743,763...14,750,903
Ensembl chrNW_004955451:14,742,735...14,750,999 		JBrowse link
G Rab7b RAB7B, member RAS oncogene family involved_in ISO (PMID:17395780) UniProt PMID:17395780 NCBI chrNW_004955406:41,615,302...41,638,157
Ensembl chrNW_004955406:41,615,302...41,638,151 		JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO (PMID:31281713) UniProt PMID:31281713 NCBI chrNW_004955408:757,426...764,989
Ensembl chrNW_004955408:757,426...771,615 		JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO (PMID:28898289) UniProt PMID:28898289 NCBI chrNW_004955410:29,366,295...29,445,205
Ensembl chrNW_004955410:29,365,844...29,444,302 		JBrowse link
G Ticam2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:19412184) UniProt PMID:19412184 NCBI chrNW_004955411:31,010,373...31,042,321 JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514)
(PMID:29407460)		 ARUK-UCL PMID:29407460 PMID:31134514 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
G Trim32 tripartite motif containing 32 involved_in ISO (PMID:28898289) UniProt PMID:28898289 NCBI chrNW_004955419:11,151,751...11,168,046
Ensembl chrNW_004955419:11,151,751...11,168,041 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:19912257) BHF-UCL PMID:19912257 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gramd4 GRAM domain containing 4 involved_in ISO (PMID:25917084) UniProt PMID:25917084 NCBI chrNW_004955413:30,603,820...30,656,940
Ensembl chrNW_004955413:30,603,580...30,656,940 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO (PMID:14716310) UniProt PMID:14716310 NCBI chrNW_004955452:17,518,345...17,549,112
Ensembl chrNW_004955452:17,529,115...17,549,664 		JBrowse link
G Ptprs protein tyrosine phosphatase receptor type S involved_in ISO (PMID:26231120) UniProt PMID:26231120 NCBI chrNW_004955495:3,943,075...3,991,361
Ensembl chrNW_004955495:3,943,170...3,990,927 		JBrowse link
G Rab7b RAB7B, member RAS oncogene family involved_in ISO (PMID:19587007) UniProt PMID:19587007 NCBI chrNW_004955406:41,615,302...41,638,157
Ensembl chrNW_004955406:41,615,302...41,638,151 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin beta 2 involved_in ISO (PMID:16378096) UniProt PMID:16378096 NCBI chrNW_004955467:10,109,985...10,118,687
Ensembl chrNW_004955467:10,110,003...10,123,022 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) UniProt PMID:20829348 NCBI chrNW_004955495:5,561,359...5,571,945
Ensembl chrNW_004955495:5,561,979...5,571,682 		JBrowse link
G Gpr108 G protein-coupled receptor 108 involved_in ISO (PMID:30332431) UniProt PMID:30332431 NCBI chrNW_004955495:2,782,549...2,789,470
Ensembl chrNW_004955495:2,782,606...2,789,815 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:28039360) UniProt PMID:28039360 NCBI chrNW_004955467:9,600,829...9,604,148
Ensembl chrNW_004955467:9,600,829...9,603,606 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 involved_in ISO (PMID:12150927) BHF-UCL PMID:12150927 NCBI chrNW_004955458:12,839,995...12,880,285
Ensembl chrNW_004955458:12,846,237...12,879,316 		JBrowse link
G Irf4 interferon regulatory factor 4 acts_upstream_of_or_within ISO (PMID:16236719) MGI PMID:16236719 NCBI chrNW_004955465:12,497,534...12,512,529
Ensembl chrNW_004955465:12,497,462...12,513,106 		JBrowse link
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 involved_in ISO (PMID:23589304) UniProt PMID:23589304 NCBI chrNW_004955476:6,611,102...6,629,294
Ensembl chrNW_004955476:6,610,103...6,629,264 		JBrowse link
G Lrrc14 leucine rich repeat containing 14 involved_in ISO (PMID:27426725) UniProt PMID:27426725 NCBI chrNW_004955454:3,142,621...3,146,470
Ensembl chrNW_004955454:3,142,636...3,146,470 		JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in ISO (PMID:20829348) UniProt PMID:20829348 NCBI chrNW_004955437:90,623...100,918
Ensembl chrNW_004955437:90,577...100,918 		JBrowse link
G Nlrp6 NLR family pyrin domain containing 6 acts_upstream_of_or_within ISO (PMID:22763455) MGI PMID:22763455 NCBI chrNW_004955476:11,755,489...11,762,781 JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in ISO (PMID:29395066) UniProt PMID:29395066 NCBI chrNW_004955428:1,062,998...1,108,711
Ensembl chrNW_004955428:1,062,998...1,115,415 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:20584979) UniProt PMID:20584979 NCBI chrNW_004955442:14,685,089...14,772,870
Ensembl chrNW_004955442:14,685,153...14,772,870 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chrNW_004955507:2,805,782...2,918,664
Ensembl chrNW_004955507:2,801,970...2,918,670 		JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004955568:263,302...349,192
Ensembl chrNW_004955568:263,302...349,192 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase acid like 3B involved_in ISO (PMID:26095358) UniProt PMID:26095358 NCBI chrNW_004955452:7,114,746...7,138,924
Ensembl chrNW_004955452:7,115,204...7,139,370 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISO (PMID:18083102) UniProt PMID:18083102 NCBI chrNW_004955416:8,361,722...8,377,629
Ensembl chrNW_004955416:8,359,207...8,377,692 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004955481:1,752,778...1,805,700
Ensembl chrNW_004955481:1,752,778...1,808,583 		JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:25774715), (PMID:25774716) UniProt PMID:25774715 PMID:25774716 NCBI chrNW_004955423:4,914,430...4,926,850
Ensembl chrNW_004955423:4,917,590...4,926,007 		JBrowse link
positive regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase involved_in ISO (PMID:25704810) UniProt PMID:25704810 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:37832545) UniProt PMID:37832545 NCBI chrNW_004955411:17,177,335...17,229,957
Ensembl chrNW_004955411:17,177,335...17,229,957 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 involved_in ISO (PMID:36745868) UniProt PMID:36745868 NCBI chrNW_004955407:42,132,216...42,154,252
Ensembl chrNW_004955407:42,132,165...42,141,992 		JBrowse link
G Tab1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 involved_in ISO (PMID:37832545) UniProt PMID:37832545 NCBI chrNW_004955413:25,290,733...25,315,267
Ensembl chrNW_004955413:25,290,828...25,313,969 		JBrowse link
G Zdhhc9 zinc finger DHHC-type palmitoyltransferase 9 involved_in ISO (PMID:37802025) UniProt PMID:37802025 NCBI chrNW_004955473:5,174,575...5,208,767
Ensembl chrNW_004955473:5,174,563...5,208,767 		JBrowse link
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:22328336) UniProt PMID:22328336 NCBI chrNW_004955447:259,654...376,147
Ensembl chrNW_004955447:259,655...376,147 		JBrowse link
G Ddx60 DExD/H-box helicase 60 involved_in ISO (PMID:21791617) UniProt PMID:21791617 NCBI chrNW_004955403:37,679,939...37,765,074
Ensembl chrNW_004955403:37,679,730...37,765,886 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (PMID:20080593) UniProt PMID:20080593 NCBI chrNW_004955451:16,186,263...16,191,928
Ensembl chrNW_004955451:16,185,510...16,191,719 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within ISO (PMID:23502856) MGI PMID:23502856 NCBI chrNW_004955583:643,575...652,393 JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISO (PMID:28943315)
(PMID:23246432)		 UniProt PMID:23246432 PMID:28943315 NCBI chrNW_004955594:551,407...613,772
Ensembl chrNW_004955594:554,081...613,661 		JBrowse link
G Btk Bruton tyrosine kinase involved_in ISO (PMID:34554188) UniProt PMID:34554188 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (PMID:23812099) UniProt PMID:23812099 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313 		JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked involved_in ISO (PMID:31511697) UniProt PMID:31511697 NCBI chrNW_004955565:1,387,043...1,403,624
Ensembl chrNW_004955565:1,386,973...1,404,220 		JBrowse link
G Dhx33 DEAH-box helicase 33 involved_in ISO (PMID:23871209) UniProt PMID:23871209 NCBI chrNW_004955467:10,797,464...10,819,083
Ensembl chrNW_004955467:10,793,934...10,818,898 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) UniProt PMID:22461501 NCBI chrNW_004955423:4,914,430...4,926,850
Ensembl chrNW_004955423:4,917,590...4,926,007 		JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO (PMID:39173637) UniProt PMID:39173637 NCBI chrNW_004955439:11,559,655...11,611,287
Ensembl chrNW_004955439:11,559,657...11,611,660 		JBrowse link
G Lats2 large tumor suppressor kinase 2 involved_in ISO (PMID:39173637) UniProt PMID:39173637 NCBI chrNW_004955497:1,711,882...1,768,177
Ensembl chrNW_004955497:1,711,205...1,761,584 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO (PMID:28943315) UniProt PMID:28943315 NCBI chrNW_004955556:1,593,552...1,705,543
Ensembl chrNW_004955556:1,593,494...1,665,784 		JBrowse link
G Mark4 microtubule affinity regulating kinase 4 involved_in ISO (PMID:28656979) UniProt PMID:28656979 NCBI chrNW_004955555:2,284,615...2,315,152
Ensembl chrNW_004955555:2,286,365...2,315,146 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:23582325) UniProt PMID:23582325 NCBI chrNW_004955415:14,691,918...14,704,782
Ensembl chrNW_004955415:14,695,438...14,703,672 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor involved_in ISO (PMID:33718825) UniProt PMID:33718825 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Nek7 NIMA related kinase 7 involved_in ISO (PMID:26642356)
(PMID:31189953), (PMID:36442502), (PMID:39173637)
(PMID:26814970)		 UniProt PMID:26642356 PMID:26814970 PMID:31189953 PMID:36442502 PMID:39173637 NCBI chrNW_004955406:34,575,292...34,714,024
Ensembl chrNW_004955406:34,626,494...34,717,546 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in ISO (PMID:29958799) UniProt PMID:29958799 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of_or_within ISO (PMID:32514138) ARUK-UCL PMID:32514138 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISO (PMID:28465465) UniProt PMID:28465465 NCBI chrNW_004955408:5,435,117...5,460,361
Ensembl chrNW_004955408:5,433,268...5,460,361 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISO (PMID:28716882) UniProt PMID:28716882 NCBI chrNW_004955409:30,554,095...30,860,588
Ensembl chrNW_004955409:30,554,013...30,860,649 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:27043286) UniProt PMID:27043286 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 involved_in ISO (PMID:31836654) UniProt PMID:31836654 NCBI chrNW_004955494:7,063,374...7,077,052 JBrowse link
G Tlr4 toll like receptor 4 involved_in ISO (PMID:23812099) UniProt PMID:23812099 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (PMID:23812099) UniProt PMID:23812099 NCBI chrNW_004955443:8,401,461...8,427,175
Ensembl chrNW_004955443:8,422,534...8,424,942 		JBrowse link
G Usp50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO (PMID:28094437) MGI PMID:28094437 NCBI chrNW_004955409:3,788,723...3,838,077
Ensembl chrNW_004955409:3,788,903...3,837,983 		JBrowse link
G Zdhhc1 zinc finger DHHC-type containing 1 involved_in ISO (PMID:39173637) UniProt PMID:39173637 NCBI chrNW_004955484:9,224,559...9,245,894
Ensembl chrNW_004955484:9,234,319...9,245,894 		JBrowse link
G Zdhhc5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO (PMID:38092000) UniProt PMID:38092000 NCBI chrNW_004955511:2,597,353...2,625,139
Ensembl chrNW_004955511:2,601,803...2,624,151 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:19570976), (PMID:21277849) UniProt PMID:19570976 PMID:21277849 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
G Slc46a2 solute carrier family 46 member 2 involved_in ISO (PMID:28539433) FlyBase PMID:28539433 NCBI chrNW_004955419:14,547,393...14,557,447
Ensembl chrNW_004955419:14,547,103...14,557,531 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nagk N-acetylglucosamine kinase involved_in ISO (PMID:36002575) UniProt PMID:36002575 NCBI chrNW_004955424:14,205,689...14,215,201
Ensembl chrNW_004955424:14,205,813...14,215,156 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chrNW_004955422:18,868,696...18,877,826
Ensembl chrNW_004955422:18,868,696...18,877,438 		JBrowse link
G Slc15a3 solute carrier family 15 member 3 involved_in ISO (PMID:24695226) UniProt PMID:24695226 NCBI chrNW_004955511:5,574,686...5,582,992
Ensembl chrNW_004955511:5,574,840...5,582,307 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:24695226) UniProt PMID:24695226 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
positive regulation of pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zdhhc5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO (PMID:31649195) UniProt PMID:31649195 NCBI chrNW_004955511:2,597,353...2,625,139
Ensembl chrNW_004955511:2,601,803...2,624,151 		JBrowse link
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:22328336) UniProt PMID:22328336 NCBI chrNW_004955447:259,654...376,147
Ensembl chrNW_004955447:259,655...376,147 		JBrowse link
G Ddx60 DExD/H-box helicase 60 involved_in ISO (PMID:21791617) UniProt PMID:21791617 NCBI chrNW_004955403:37,679,939...37,765,074
Ensembl chrNW_004955403:37,679,730...37,765,886 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (PMID:20080593) UniProt PMID:20080593 NCBI chrNW_004955451:16,186,263...16,191,928
Ensembl chrNW_004955451:16,185,510...16,191,719 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase like involved_in ISO (PMID:25925578) ARUK-UCL PMID:25925578 NCBI chrNW_004955455:10,658,080...10,682,493
Ensembl chrNW_004955455:10,657,440...10,682,546 		JBrowse link
G Pum1 pumilio RNA binding family member 1 involved_in ISO (PMID:25340845) UniProt PMID:25340845 NCBI chrNW_004955452:9,487,725...9,623,565
Ensembl chrNW_004955452:9,487,725...9,624,066 		JBrowse link
G Pum2 pumilio RNA binding family member 2 involved_in ISO (PMID:25340845) UniProt PMID:25340845 NCBI chrNW_004955469:2,810,825...2,886,911
Ensembl chrNW_004955469:2,810,573...2,886,611 		JBrowse link
G Trim15 tripartite motif containing 15 involved_in ISO (PMID:23077300) UniProt PMID:23077300 NCBI chrNW_004955583:277,564...283,422 JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in ISO (PMID:24399297) CACAO PMID:24399297 NCBI chrNW_004955458:9,440,645...9,533,653
Ensembl chrNW_004955458:9,403,097...9,533,653 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) UniProt PMID:21102435 NCBI chrNW_004955494:3,925,478...3,985,469
Ensembl chrNW_004955494:3,926,413...3,983,736 		JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO (PMID:30193849) UniProt PMID:30193849 NCBI chrNW_004955597:194,912...197,697
Ensembl chrNW_004955597:195,002...196,231 		JBrowse link
positive regulation of toll-like receptor 13 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Treml4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (PMID:25848864) UniProt PMID:25848864 NCBI chrNW_004955437:7,827,329...7,846,406 JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) UniProt PMID:19865078 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:16267105) UniProt PMID:16267105 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339 		JBrowse link
G LOC102004641 cytochrome b-245 light chain involved_in ISO (PMID:22423966) UniProt PMID:22423966 NCBI chrNW_004955541:2,570,843...2,573,822
Ensembl chrNW_004955541:2,569,727...2,574,118 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:26599367), (PMID:28471450) UniProt PMID:26599367 PMID:28471450 NCBI chrNW_004955463:4,900,115...4,993,793
Ensembl chrNW_004955463:4,900,060...4,993,793 		JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in ISO (PMID:28471450) UniProt PMID:28471450 NCBI chrNW_004955418:5,429,038...5,493,393
Ensembl chrNW_004955418:5,450,908...5,490,926 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) BHF-UCL PMID:19509286 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Tlr1 toll like receptor 1 involved_in ISO (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chrNW_004955443:8,442,419...8,450,318
Ensembl chrNW_004955443:8,447,956...8,450,382 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) UniProt PMID:19865078 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Flot1 flotillin 1 involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004955583:717,246...729,924
Ensembl chrNW_004955583:713,560...729,924 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004955424:20,212,077...20,263,761
Ensembl chrNW_004955424:20,211,600...20,263,761 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23871208) UniProt PMID:23871208 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:17322885) BHF-UCL PMID:17322885 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Trim3 tripartite motif containing 3 involved_in ISO (PMID:32878999) UniProt PMID:32878999 NCBI chrNW_004955414:22,181,999...22,207,244
Ensembl chrNW_004955414:22,181,857...22,207,244 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO (PMID:25736436) UniProt PMID:25736436 NCBI chrNW_004955453:10,101,576...10,148,205
Ensembl chrNW_004955453:10,101,576...10,149,710 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (PMID:24380872) UniProt PMID:24380872 NCBI chrNW_004955418:73,736...75,345
Ensembl chrNW_004955418:73,897...75,224 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:18622013) UniProt PMID:18622013 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:16267105) UniProt PMID:16267105 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339 		JBrowse link
G Ifi35 interferon induced protein 35 involved_in ISO (PMID:29038465) UniProt PMID:29038465 NCBI chrNW_004955451:16,790,998...16,798,993
Ensembl chrNW_004955451:16,790,383...16,802,664 		JBrowse link
G LOC102006100 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:19412184)
(PMID:22685567)		 UniProt PMID:19412184 PMID:22685567 NCBI chrNW_004955408:35,342,733...35,382,821
Ensembl chrNW_004955408:35,374,508...35,382,314 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) UniProt PMID:20345905 NCBI chrNW_004955420:25,580,449...25,604,277
Ensembl chrNW_004955420:25,580,359...25,604,331 		JBrowse link
G Ninj1 ninjurin 1 involved_in ISO (PMID:25860173) UniProt PMID:25860173 NCBI chrNW_004955515:4,892,748...4,905,627
Ensembl chrNW_004955515:4,892,039...4,907,323 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 involved_in ISO (PMID:18511497) BHF-UCL PMID:18511497 NCBI chrNW_004955422:940,310...954,170
Ensembl chrNW_004955422:940,310...949,049 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004955424:20,212,077...20,263,761
Ensembl chrNW_004955424:20,211,600...20,263,761 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23871208) UniProt PMID:23871208 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Ticam2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:22685567)
(PMID:19412184)		 UniProt PMID:19412184 PMID:22685567 NCBI chrNW_004955411:31,010,373...31,042,321 JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) BHF-UCL PMID:19509286 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO (PMID:25736436) UniProt PMID:25736436 NCBI chrNW_004955453:10,101,576...10,148,205
Ensembl chrNW_004955453:10,101,576...10,149,710 		JBrowse link
G Znrf1 zinc and ring finger 1 involved_in ISO (PMID:28593998) UniProt PMID:28593998 NCBI chrNW_004955484:2,468,392...2,566,539
Ensembl chrNW_004955484:2,468,392...2,566,539 		JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3 X-linked involved_in ISO (PMID:30341167) UniProt PMID:30341167 NCBI chrNW_004955565:1,387,043...1,403,624
Ensembl chrNW_004955565:1,386,973...1,404,220 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23871208) UniProt PMID:23871208 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISO (PMID:21435586) UniProt PMID:21435586 NCBI chrNW_004955487:1,988,226...2,001,731
Ensembl chrNW_004955487:1,987,405...2,001,731 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:25238095), (PMID:32433612)
(PMID:21045126), (PMID:25238095)		 UniProt PMID:21045126 PMID:25238095 PMID:32433612 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:32433612) UniProt PMID:32433612 NCBI chrNW_004955531:207,614...293,127
Ensembl chrNW_004955531:267,216...293,127 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (PMID:25848864) UniProt PMID:25848864 NCBI chrNW_004955437:7,827,329...7,846,406 JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3 X-linked involved_in ISO (PMID:30341167) UniProt PMID:30341167 NCBI chrNW_004955565:1,387,043...1,403,624
Ensembl chrNW_004955565:1,386,973...1,404,220 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:32433612) UniProt PMID:32433612 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:32433612) UniProt PMID:32433612 NCBI chrNW_004955531:207,614...293,127
Ensembl chrNW_004955531:267,216...293,127 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23871208) UniProt PMID:23871208 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISO (PMID:21435586) UniProt PMID:21435586 NCBI chrNW_004955487:1,988,226...2,001,731
Ensembl chrNW_004955487:1,987,405...2,001,731 		JBrowse link
G Rtn4 reticulon 4 involved_in ISO (PMID:25917084) UniProt PMID:25917084 NCBI chrNW_004955424:28,061,346...28,125,838 JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:25238095)
(PMID:21045126), (PMID:21277849), (PMID:25238095)		 UniProt PMID:21045126 PMID:21277849 PMID:25238095 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
G Tlr9 toll like receptor 9 involved_in ISO (PMID:18931679) UniProt PMID:18931679 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (PMID:25848864) UniProt PMID:25848864 NCBI chrNW_004955437:7,827,329...7,846,406 JBrowse link
G Zdhhc3 zinc finger DHHC-type palmitoyltransferase 3 involved_in ISO (PMID:38169466) UniProt PMID:38169466 NCBI chrNW_004955420:26,698,168...26,736,364
Ensembl chrNW_004955420:26,698,168...26,733,953 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdi1 GDP dissociation inhibitor 1 involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004955580:935,021...941,081
Ensembl chrNW_004955580:934,798...941,081 		JBrowse link
G Lrch4 leucine rich repeats and calponin homology domain containing 4 involved_in ISO (PMID:16449650) UniProt PMID:16449650 NCBI chrNW_004955573:315,764...327,833
Ensembl chrNW_004955573:315,766...331,477 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chrNW_004955507:2,805,782...2,918,664
Ensembl chrNW_004955507:2,801,970...2,918,670 		JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf1 interferon regulatory factor 1 involved_in ISO (PMID:17018642) UniProt PMID:17018642 NCBI chrNW_004955408:3,882,282...3,887,965
Ensembl chrNW_004955408:3,880,155...3,887,973 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:15800576) UniProt PMID:15800576 NCBI chrNW_004955476:11,442,781...11,445,706
Ensembl chrNW_004955476:11,443,272...11,445,657 		JBrowse link
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:15800576) UniProt PMID:15800576 NCBI chrNW_004955476:11,442,781...11,445,706
Ensembl chrNW_004955476:11,443,272...11,445,657 		JBrowse link
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in ISO (PMID:22801494) UniProt PMID:22801494 NCBI chrNW_004955441:4,908,318...4,944,343 JBrowse link
G Kcnk13 potassium two pore domain channel subfamily K member 13 involved_in ISO (PMID:35353387) UniProt PMID:35353387 NCBI chrNW_004955438:12,522,063...12,660,078
Ensembl chrNW_004955438:12,522,737...12,663,480 		JBrowse link
regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a2 solute carrier family 15 member 2 involved_in ISO (PMID:29784761) UniProt PMID:29784761 NCBI chrNW_004955427:21,221,778...21,255,725
Ensembl chrNW_004955427:21,221,750...21,255,725 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:29784761) UniProt PMID:29784761 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chrNW_004955422:18,868,696...18,877,826
Ensembl chrNW_004955422:18,868,696...18,877,438 		JBrowse link
regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:27824081) UniProt PMID:27824081 NCBI chrNW_004955574:1,505,997...1,514,680
Ensembl chrNW_004955574:1,506,022...1,517,130 		JBrowse link
regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flot2 flotillin 2 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004955481:4,276,847...4,298,523
Ensembl chrNW_004955481:4,276,860...4,298,523 		JBrowse link
G Hcfc2 host cell factor C2 acts_upstream_of_or_within ISO (PMID:28970238) MGI PMID:28970238 NCBI chrNW_004955405:38,729,700...38,758,398
Ensembl chrNW_004955405:38,730,054...38,760,115 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:37158982) UniProt PMID:37158982 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:27219021) UniProt PMID:27219021 NCBI chrNW_004955430:6,986,977...7,018,938
Ensembl chrNW_004955430:6,986,759...7,018,938 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:27219021) UniProt PMID:27219021 NCBI chrNW_004955405:39,503,020...39,540,069
Ensembl chrNW_004955405:39,503,020...39,540,335 		JBrowse link
G Flot1 flotillin 1 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004955583:717,246...729,924
Ensembl chrNW_004955583:713,560...729,924 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO (PMID:19289601) UniProt PMID:19289601 NCBI chrNW_004955446:1,020,707...1,098,327
Ensembl chrNW_004955446:1,020,043...1,098,820 		JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) ARUK-UCL PMID:31134514 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313 		JBrowse link
G Esr1 estrogen receptor 1 acts_upstream_of_or_within ISO (PMID:22659029) MGI PMID:22659029 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:20547752) UniProt PMID:20547752 NCBI chrNW_004955423:2,024,084...2,032,530
Ensembl chrNW_004955423:2,022,417...2,033,149 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:20616063) UniProt PMID:20616063 NCBI chrNW_004955463:4,900,115...4,993,793
Ensembl chrNW_004955463:4,900,060...4,993,793 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12572
    regulation of biological process 8766
      regulation of response to stimulus 3492
        regulation of signal transduction 2715
          regulation of pattern recognition receptor signaling pathway 164
            positive regulation of pattern recognition receptor signaling pathway + 73
            regulation of cytoplasmic pattern recognition receptor signaling pathway + 114
            regulation of peptidoglycan recognition protein signaling pathway + 0
            regulation of toll-like receptor 1 signaling pathway + 0
            regulation of toll-like receptor 10 signaling pathway + 0
            regulation of toll-like receptor 15 signaling pathway + 0
            regulation of toll-like receptor 2 signaling pathway + 12
            regulation of toll-like receptor 4 signaling pathway + 29
            regulation of toll-like receptor 5 signaling pathway + 1
            regulation of toll-like receptor 6 signaling pathway + 1
            regulation of toll-like receptor signaling pathway + 28
Path 2
Term Annotations click to browse term
  biological_process 12572
    response to stimulus 6771
      response to biotic stimulus 1319
        response to external biotic stimulus 1274
          response to other organism 1271
            defense response to other organism 857
              defense response to symbiont 697
                innate immune response 639
                  regulation of innate immune response 395
                    positive regulation of innate immune response 324
                      activation of innate immune response 262
                        innate immune response-activating signaling pathway 248
                          pattern recognition receptor signaling pathway 247
                            regulation of pattern recognition receptor signaling pathway 164
                              positive regulation of pattern recognition receptor signaling pathway + 73
                              regulation of cytoplasmic pattern recognition receptor signaling pathway + 114
                              regulation of peptidoglycan recognition protein signaling pathway + 0
                              regulation of toll-like receptor 1 signaling pathway + 0
                              regulation of toll-like receptor 10 signaling pathway + 0
                              regulation of toll-like receptor 15 signaling pathway + 0
                              regulation of toll-like receptor 2 signaling pathway + 12
                              regulation of toll-like receptor 4 signaling pathway + 29
                              regulation of toll-like receptor 5 signaling pathway + 1
                              regulation of toll-like receptor 6 signaling pathway + 1
                              regulation of toll-like receptor signaling pathway + 28
paths to the root