Ppp2ca (protein phosphatase 2 catalytic subunit alpha)

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Gene: Ppp2ca (protein phosphatase 2 catalytic subunit alpha) Chinchilla lanigera

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Symbol:

Ppp2ca

Name:

protein phosphatase 2 catalytic subunit alpha

RGD ID:

8782177

Description:

ENCODES a protein that exhibits beta-2 adrenergic receptor binding (ortholog); enzyme binding (ortholog); GABA receptor binding (ortholog); INVOLVED IN cardiac ventricle development (ortholog); cellular response to calcium ion (ortholog); cellular response to cytokine stimulus (ortholog); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; ataxia telangiectasia-mutated (ATM) signaling pathway; calcium/calmodulin dependent kinase 2 signaling pathway; ASSOCIATED WITH asthma (ortholog); congestive heart failure (ortholog); Experimental Liver Neoplasms (ortholog); FOUND IN chromosome, centromeric region (ortholog); cytoplasm (ortholog); cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	5,433,268 - 5,460,361 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955408	5,435,117 - 5,460,361 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asthma (ISO)

congestive heart failure (ISO)

Experimental Liver Neoplasms (ISO)

familial adenomatous polyposis 1 (ISO)

genetic disease (ISO)

heart disease (ISO)

Hereditary Neoplastic Syndromes (ISO)

Hyperalgesia (ISO)

Myocardial Ischemia (ISO)

Neurodevelopmental Disorder and Language Delay with or Without Structural Brain Abnormalities (ISO)

Neurodevelopmental Disorders (ISO)

Parkinson's disease (ISO)

prostate cancer (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cardiac ventricle development (ISO)

cellular response to calcium ion (ISO)

cellular response to cytokine stimulus (ISO)

cellular response to ethanol (ISO)

cellular response to follicle-stimulating hormone stimulus (ISO)

cellular response to glucose stimulus (ISO)

cellular response to insulin stimulus (ISO)

cellular response to steroid hormone stimulus (ISO)

heart development (ISO)

mesoderm development (ISO)

negative regulation of calcium ion transmembrane transporter activity (ISO)

negative regulation of epithelial to mesenchymal transition (ISO)

negative regulation of glycolytic process through fructose-6-phosphate (ISO)

negative regulation of hippo signaling (ISO)

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

negative regulation of protein import into nucleus (ISO)

negative regulation of protein phosphorylation (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

peptidyl-threonine dephosphorylation (ISO)

positive regulation of apoptotic process (ISO)

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process (ISO)

positive regulation of dephosphorylation (ISO)

positive regulation of NLRP3 inflammasome complex assembly (ISO)

positive regulation of protein serine/threonine kinase activity (ISO)

protein dephosphorylation (ISO)

regulation of G1/S transition of mitotic cell cycle (ISO)

regulation of protein autophosphorylation (ISO)

regulation of protein catabolic process (ISO)

regulation of protein phosphorylation (ISO)

regulation of signaling receptor activity (ISO)

response to lead ion (ISO)

T cell homeostasis (ISO)

Cellular Component

chromosome, centromeric region (ISO)

cytoplasm (ISO)

cytosol (ISO)

FAR/SIN/STRIPAK complex (ISO)

membrane raft (ISO)

plasma membrane (ISO)

protein phosphatase type 2A complex (ISO)

protein serine/threonine phosphatase complex (ISO)

synapse (ISO)

terminal bouton (ISO)

Molecular Function

beta-2 adrenergic receptor binding (ISO)

enzyme binding (ISO)

GABA receptor binding (ISO)

identical protein binding (ISO)

phosphoprotein phosphatase activity (ISO)

protein antigen binding (ISO)

protein binding (ISO)

protein domain specific binding (ISO)

protein heterodimerization activity (ISO)

protein kinase B binding (ISO)

protein kinase binding (ISO)

protein phosphatase 2A binding (ISO)

protein phosphatase binding (ISO)

protein serine/threonine phosphatase activity (ISO)

protein tyrosine phosphatase activity (ISO)

protein-containing complex binding (ISO)

tau protein binding (ISO)

transmembrane transporter binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

adenosine monophosphate-activated protein kinase (AMPK) signaling pathway (ISO)

ataxia telangiectasia-mutated (ATM) signaling pathway (ISO)

calcium/calmodulin dependent kinase 2 signaling pathway (ISO)

dopamine signaling pathway (ISO)

p53 signaling pathway (ISO)

phosphatidylinositol 3-kinase-Akt signaling pathway (ISO)

platelet-derived growth factor signaling pathway (ISO)

transforming growth factor-beta Smad dependent signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Ppp2ca
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	5,433,268 - 5,460,361 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955408	5,435,117 - 5,460,361 (-)	NCBI	ChiLan1.0	ChiLan1.0

PPP2CA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	134,194,332 - 134,226,073 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	134,194,035 - 134,226,073 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	133,530,023 - 133,561,764 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	133,560,047 - 133,589,849 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	133,560,046 - 133,589,849	NCBI
Celera	5	129,655,849 - 129,685,663 (-)	NCBI		Celera
Cytogenetic Map	5	q31.1	NCBI
HuRef	5	128,717,117 - 128,746,747 (-)	NCBI		HuRef
CHM1_1	5	132,964,711 - 132,994,524 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	134,717,969 - 134,749,722 (-)	NCBI		T2T-CHM13v2.0

Ppp2ca
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	51,989,651 - 52,013,576 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	51,989,508 - 52,018,605 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	52,098,824 - 52,122,749 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	52,098,681 - 52,127,778 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	51,912,326 - 51,936,251 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	51,942,247 - 51,966,172 (+)	NCBI		MGSCv36	mm8
Celera	11	56,667,217 - 56,691,076 (+)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	31.86	NCBI

Ppp2ca
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	36,856,534 - 36,878,789 (+)	NCBI		GRCr8
mRatBN7.2	10	36,358,110 - 36,377,864 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	36,358,101 - 36,377,862 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	41,052,411 - 41,072,171 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	40,542,376 - 40,562,136 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	36,046,099 - 36,065,860 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	37,534,449 - 37,554,861 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	37,535,871 - 37,554,664 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	37,324,233 - 37,343,985 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	37,621,256 - 37,641,008 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	37,627,685 - 37,647,436 (+)	NCBI
Celera	10	35,713,154 - 35,732,937 (+)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

PPP2CA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	129,495,422 - 129,527,796 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	127,634,159 - 127,667,358 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	129,599,606 - 129,629,312 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	135,751,964 - 135,761,395 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	135,751,958 - 135,765,786 (-)	Ensembl	panpan1.1		panPan2

PPP2CA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	22,388,327 - 22,410,052 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	22,385,257 - 22,410,052 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	21,134,537 - 21,156,029 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	23,189,481 - 23,211,243 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	23,188,436 - 23,211,451 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	21,889,485 - 21,911,229 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	21,754,643 - 21,776,444 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	22,397,162 - 22,418,841 (-)	NCBI		UU_Cfam_GSD_1.0

Ppp2ca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	114,028,481 - 114,052,523 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936647	1,031,119 - 1,055,149 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936647	1,031,118 - 1,055,961 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPP2CA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	136,494,541 - 136,522,646 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	136,497,780 - 136,522,630 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	142,095,024 - 142,123,724 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPP2CA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	36,999,110 - 37,028,916 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	36,997,078 - 37,029,280 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	40,904,228 - 40,936,193 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppp2ca
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	38,012,392 - 38,036,914 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624733	38,012,694 - 38,033,745 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005376137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01008137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01008138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01004946	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000023053 ⟹ ENSCLAP00000022842

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955408	5,433,268 - 5,460,361 (-)	Ensembl

RefSeq Acc Id:

XM_005376137 ⟹ XP_005376194

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955408	5,435,117 - 5,460,361 (-)	NCBI

Sequence:

show sequence

CGCCATTACAGGGCCGAGCTCCCGAGCTAGGGCGAGCTGAGGAGGAGCCGCAGCCGCCGGGGGC
CGAGCGCTGCAGGGAGAGCCAGCGGGCCGGCGCCAGCGCCCAGCGACCGCCAGGGACCACAAGA
ACACCCCAGGAACCGGTGGCGGAGTGTGCGTGTGGCCCGTCTGCGGGCGGCGGCGCGGGAGCAG
CGCGGAGCGGCGGCCGGTTCGGGCGGGTGGCATCATGGACGAGAAGGTGTTCACCAAGGAGCTG
GACCAGTGGATCGAGCAGCTGAATGAGTGCAAGCAGCTGTCCGAATCGCAGGTTAAGAGCCTCT
GCGAGAAGGCTAAAGAAATCCTGACAAAAGAGTCCAACGTGCAAGAGGTTCGATGTCCAGTTAC
TGTCTGTGGAGATGTACATGGGCAATTTCATGATCTCATGGAACTGTTTAGAATTGGTGGCAAA
TCACCAGACACAAATTATTTGTTTATGGGAGATTATGTCGACCGAGGATATTATTCAGTTGAAA
CAGTCACACTGCTTGTAGCTCTTAAGGTTCGTTACCGTGAACGCATCACTATTCTTCGAGGGAA
TCATGAGAGCAGACAAATCACACAAGTTTATGGTTTCTATGATGAGTGTTTAAGAAAATATGGA
AATGCAAATGTTTGGAAATATTTTACAGATCTTTTTGATTATCTTCCTCTCACTGCCTTGGTGG
ATGGGCAGATCTTCTGTCTACATGGTGGCCTCTCTCCGTCCATAGATACACTGGATCACATCAG
AGCACTTGATCGCCTACAAGAAGTTCCCCATGAGGGTCCAATGTGTGATTTGCTGTGGTCAGAT
CCAGACGATCGTGGTGGTTGGGGTATATCTCCTCGGGGAGCTGGTTACACCTTTGGCCAAGATA
TATCGGAGACATTTAATCATGCCAATGGCCTCACATTGGTGTCTAGAGCTCACCAGCTGGTGAT
GGAGGGATATAACTGGTGCCATGACCGGAATGTAGTCACAATTTTCAGTGCTCCAAACTATTGT
TATCGTTGTGGTAACCAAGCTGCAATCATGGAACTTGATGATACTCTAAAATATTCTTTCTTGC
AGTTTGATCCAGCACCTCGTAGAGGCGAGCCACATGTCACTCGTCGTACCCCAGACTACTTCCT
GTAATGAAATTTTAAACTTGTACAGTATTGCCATGAACCATTTATTGACCTAATGGAAATGGGA
AGAGCAACAGTAACTCCAGAGTGTCAGAAAATAGTTAACATTCAAAAACTTGTTTTCACACGGA
CCAAAAGATGTGCCATATAAAAATACAAAGCCTCTTGTCATCAACAGCCGTGACCACTTTAGAA
TGAACCAGTTCATTGCATGCTGAAGCGACATTGTTGGTCAAGAAACCAGTTTCTGGCATAGCGC
TATTTGTAGTTACTTTTTGCTTTCTCTGAGAGACTGCAGATAATAAGATGTAAACATTAACACC
TCGTGAATACAATTTAACTTCCATTTAGCTATAGCTTTACTCAGCATGACTGTAGATAAGGATA
GCAGCAAACAATCATTGGCGCTTAATGAACATTTTTAAAATAAGTACCAAGCCTCCCCTTTACT
TGTGAGTTTTGAACTTGTTTTGTTTATTTTCAGGGATACTGTTTAATTTAATTGTATGATTTGT
CTGCACTCAGTTTATTCCCTTCTCAAATCTCACCCCTATGTTCTTTGTTATTGTCAGAACCTGG
TGAGTTGTTCTGAACAGAAATGTTTCCCCCTTCCTGTAAGACGATGTTACTGCACAAGAATACT
GCAGTGTTTTTCATAATAAACTTGTGAACTAAGAACTGAGAAAGTCAAATTTTAATTGTATCAG
TGGGCAAGACTGGTGCTGTTTAAAGATAAATCTTTAATAAATTTTAGAATTTGTAGAATACTAG
GTAAACTAAAATAAATATCAAGGCCACTACACGACCTCTCTGGTAACTTTCTGACATTCTTCAG
ATGAACTTCAGGATTTCTTTGTGTTACCTATAGTGTAATTTGTCATATTGCTGGTATACTTTAA
ACTTGTCTTTAAGAAGGGAAATCTGTGCTGCTTTGGTAAGATCTAATTGTTAAACTATGTAACA
TCAGGGTTCCGGTGTTAGGATTTGTTTAAAGTGGCATGTTTTCAGGTAGAGCTTAAATGATGTG
TCTACTTAGTACAGTTTCTGGTTATAAATATTATATTGCTATGTATATTTAAGAGTTACATGAA
CTTTTAAAAATAATTGACAGATTGGTAAGTTCTTAACAAATATCTGTACATTGCCTGTTGAATC
ATGTGATCTTAATGTCTTAGAAAGCTGTTAAAGCATTAACCTGTAAGTGATAATCAGTGAAAGC
AAATAGAAAATTATTATTGGATCATTGTTTAGTGTAAAGTACATTTACCCAAAAGGAAGTGGCG
TTTGAAGTGCCAGTGCTCAACATTTAATGAGTTTTCCCCCTTCTTATCCTTTGAATAGGATTAG
AGGTTCTGTGCAAACTAATACTTGATTTTTTTAAGCTACCAGGGTACACTTCAGAGAACTAATC
ATTAATTGTGTGTGAGTATAGCTAATAAACATTTCTTTGCTTTGTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005376194	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000001618.1
	ENSCLAP00000022842
	ENSCLAP00000022842.1

RefSeq Acc Id:

XP_005376194 ⟸ XM_005376137

- UniProtKB:

A0A8C2YTU5 (UniProtKB/TrEMBL), A0A8C2YIQ9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHD
LMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYG
FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHE
GPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNV
VTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL

hide sequence

Ensembl Acc Id:

ENSCLAP00000022842 ⟸ ENSCLAT00000023053

Protein Domains

Serine/threonine specific protein phosphatases

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000001213	UniProtKB/TrEMBL
	ENSCLAG00000015668	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000001661.1	UniProtKB/TrEMBL
	ENSCLAT00000023053	ENTREZGENE
	ENSCLAT00000023053.1	UniProtKB/TrEMBL
Gene3D-CATH	3.60.21.10	UniProtKB/TrEMBL
InterPro	Calcineurin-like_PHP_ApaH	UniProtKB/TrEMBL
	Metallo-depent_PP-like	UniProtKB/TrEMBL
	PPA2-like	UniProtKB/TrEMBL
	Ser/Thr-sp_prot-phosphatase	UniProtKB/TrEMBL
NCBI Gene	Ppp2ca	ENTREZGENE
PANTHER	SERINE/THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT ALPHA ISOFORM	UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT BETA ISOFORM	UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED	UniProtKB/TrEMBL
Pfam	Metallophos	UniProtKB/TrEMBL
PRINTS	STPHPHTASE	UniProtKB/TrEMBL
PROSITE	SER_THR_PHOSPHATASE	UniProtKB/TrEMBL
SMART	PP2Ac	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56300	UniProtKB/TrEMBL
UniProt	A0A8C2YIQ9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2YTU5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Ppp2ca	protein phosphatase 2 catalytic subunit alpha		protein phosphatase 2, catalytic subunit, alpha isozyme	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)