Smpdl3b (sphingomyelin phosphodiesterase acid like 3B)

Gene: Smpdl3b (sphingomyelin phosphodiesterase acid like 3B) Chinchilla lanigera

Analyze

Symbol:

Smpdl3b

Name:

sphingomyelin phosphodiesterase acid like 3B

RGD ID:

9018738

Description:

ENCODES a protein that exhibits phosphoric diester hydrolase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN membrane lipid catabolic process (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of toll-like receptor signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

acid sphingomyelinase-like phosphodiesterase 3b; sphingomyelin phosphodiesterase, acid-like 3B

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	7,115,204 - 7,139,370 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	7,114,746 - 7,138,924 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

membrane lipid catabolic process (ISO)

negative regulation of inflammatory response (ISO)

negative regulation of toll-like receptor signaling pathway (ISO)

Cellular Component

plasma membrane (ISO)

Molecular Function

phosphoric diester hydrolase activity (ISO)

protein binding (ISO)

zinc ion binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Smpdl3b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	7,115,204 - 7,139,370 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	7,114,746 - 7,138,924 (+)	NCBI	ChiLan1.0	ChiLan1.0

SMPDL3B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	27,935,000 - 27,959,152 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	27,935,000 - 27,959,157 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	28,261,511 - 28,285,663 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	28,134,091 - 28,158,250 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	27,945,645 - 27,969,804	NCBI
Celera	1	26,657,114 - 26,681,282 (+)	NCBI		Celera
Cytogenetic Map	1	p35.3	NCBI
HuRef	1	26,516,904 - 26,541,073 (+)	NCBI		HuRef
CHM1_1	1	28,377,018 - 28,401,193 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	27,776,819 - 27,800,989 (+)	NCBI		T2T-CHM13v2.0

Smpdl3b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	132,460,277 - 132,484,558 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	132,460,277 - 132,484,563 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	132,732,966 - 132,757,171 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	132,732,966 - 132,757,252 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	132,288,881 - 132,313,086 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	132,005,042 - 132,029,247 (-)	NCBI		MGSCv36	mm8
Celera	4	130,895,309 - 130,919,092 (-)	NCBI		Celera
Cytogenetic Map	4	D2.3	NCBI
cM Map	4	65.82	NCBI

Smpdl3b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	150,228,607 - 150,250,688 (-)	NCBI		GRCr8
mRatBN7.2	5	144,944,618 - 144,966,703 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	144,944,636 - 144,966,720 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	147,644,413 - 147,666,468 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	149,414,004 - 149,436,061 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	149,402,583 - 149,424,668 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	150,925,150 - 150,946,994 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	150,925,370 - 150,949,931 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	154,592,752 - 154,614,208 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	152,390,454 - 152,415,338 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	152,400,451 - 152,424,958 (+)	NCBI
Celera	5	143,370,153 - 143,390,983 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

SMPDL3B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	198,894,311 - 198,921,240 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	198,011,239 - 198,038,177 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	27,194,502 - 27,219,454 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	28,234,761 - 28,259,079 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	28,234,761 - 28,259,079 (+)	Ensembl	panpan1.1		panPan2

SMPDL3B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	72,427,085 - 72,450,547 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	72,418,872 - 72,450,737 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	69,004,783 - 69,028,059 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	72,987,362 - 73,010,366 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	72,987,235 - 73,010,425 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	69,814,503 - 69,837,784 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	70,824,997 - 70,848,067 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	71,821,141 - 71,844,227 (-)	NCBI		UU_Cfam_GSD_1.0

Smpdl3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	46,333,773 - 46,355,474 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	12,158,628 - 12,179,993 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	12,158,628 - 12,179,993 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SMPDL3B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	85,060,317 - 85,084,480 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	85,060,639 - 85,084,483 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	78,600,796 - 78,625,040 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SMPDL3B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	104,852,055 - 104,872,123 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666033	11,600,330 - 11,622,556 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Smpdl3b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	11,785,640 - 11,807,084 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	11,785,739 - 11,807,351 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005394936	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013519538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013519539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01044133	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01044134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01044135	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01044136	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDK01112309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000017308 ⟹ ENSCLAP00000017139

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955452	7,115,204 - 7,139,370 (+)	Ensembl

RefSeq Acc Id:

XM_005394936 ⟹ XP_005394993

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955452	7,114,746 - 7,138,924 (+)	NCBI

Sequence:

show sequence

GCAGGCGCTTATACCACTGAGCTATATCCCAGGGCCCCTGTTTATTTTGATGGTGCAGTGAGTC
AAACCCAAGGACTGACACATGCCAGACAAGTGCTTTACTACTGAGTCAGACCTCAGCCCCCTGC
CAGATTATTTTGAAGCAAAGTACAGAGATCAGATCACCCTGTCCATACTCTTTCCATACATATG
CCAAAAAGAGAAAGGCTCTTTTTCTAACAGGCAGCACCTGGGGAGGCAGGTGCTGCTCGCGCGG
AAGAGTGCAAAGGTCTGCTGCCAGCGCCCTGCCCGGTGACCTCTCGGCGGCCCCGCGCCGCTCA
CACCCTGCTGGGAGAGGGAGAGAAGCCAGGGGAGCCGGCTTGGCGCATAGGTAGCAGGAAGTCC
CGCTCAGGCACGTGGCCGGCAGCAACTCCTTCCAAAACCTGCGGCGCAGAGGGAGGAACGGCTC
CAGAGGACAGATGGCTGCCGGGAGGGGCGCCCCGAGGATGAGGCCGCTGCTGTGGCCGATTTTC
CTGGCCGTCTGCGGAGTCTCCAGCGCCGCGCCAGGGAGGTTCTGGCACATCTCTGACCTGCACC
TTGACCCCAACTACACGGTATCCCAAGACCCCCGCGAAGTGTGCCCCTCAGCGGGCTCCCAGCT
GGTGCACAACGCGGGCCCCTGGGGCGACTACCTCTGTGACTCGCCCTGGGCCCTCATCAACGCT
TCCATCTACGCCATGAAGGAGATCGAGCCGGAGCCAGACTTCATCCTGTGGACAGGCGATGATA
CTCCACACGTGCCCGACGAGAAGCTGGGAGAGGCGGCGGTGCTGGAAATCGTGGGACGTCTGAC
CAGCCTCATCAGGGAGGTCTTCCCAGATACTAAAGTCTATGCTGCTATGGGAAATCACGACTTT
CACCCCAAAAGCCAGTTCCCAGCGAAGAGCAACAGTATCTACCATCAGGTAGCAGAACTGTGGA
GACCCTGGCTTAGAAATGAATCCGTCGCTCTCTTCAAAGAAGGTGCCTTCTATTCGGAGACGCT
GCCGGGTGCCAGCAGCGCGCACCGCATCGTGGTGCTCAACACCAATCTCTACTACAGCAACAAC
CGGCTCACGGCGGACATAGCCGACCCCAGCCAGCAGTTCCAGTGGCTGGACGCTGTTCTGACCA
ACGCGTCCCAAGCAGGGGAGAAGGTCTACATCATTGGCCACATACCCCCAGGGTTCTTCGAGAA
GACGCGGGACAAGGCGTGGTTCCGGAGTGGCTTCAACAAGGAGTACCTGAAGGCGGTCCGGAAG
CACCACAGGGTCATAGCAGGGCAGTTCTTCGGGCACCAGCACACTGACAGCTTTCGGATGTTCT
ACGACGACGCAGGAGCACCCATCAGCGTCATGTTCCTTGCCCCTGGGGTCACCCCGTGGAAAAC
CACGTTGGTTGGGGTGGTCAACGGCGCCAACAACCCCGGCATCCGGCTGTTCGAGTATGACCGA
GCCACGCTGAGCCTGCAGGACATGATGACCTACTTCATGAACCTGAGCCAGGCGAATGCGCAGA
ACAACCCACGCTGGGAGCTCGAGTACCGGCTGACTGAGGCCTATGGGGTGCCGGATGCCAGTGT
CCGCTCCATGCAAGAGGTAGCGACTGGCATTGCTAGTGACCAGGACAAGCTGCAGCGCTACTAC
GATTACAACTCTGTGAGCTACGACACTACACCCTGTGGCGAGACCTGCCGGACGGAGTTCCTGT
GTGCCATGCAGGAGGTGGACTTCGACGCCTACTCCATCTGCCTGAGGAGCATGGGCGCCAGGCC
CAGGATAGAGGTCCTGCTGGCGCTGCTGGCCATGCTGCTGGGCCTGCAGGCTCTACTTGCACCC
TGACCTTGGGCACCAACCTCTCCTTGCGGGCGCATCTTCCTTCCAATAAATTGGGGCAGTGTCA
CCCCTCAAAAGCTGA

hide sequence

RefSeq Acc Id:

XM_013519538 ⟹ XP_013374992

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955452	7,115,298 - 7,138,924 (+)	NCBI

Sequence:

show sequence

GGGCAGGGCTACCTGATGGCTTTGTTTCGGGCTGTGCACTCCGGCCGGGCTGCGGCCAGCTGCT
CACAGAAAGCGCTGCTGAAAACCGCGAGGCGGGGACGCAGGGAACGACGCTCAGCCGGGCGGCC
ACCACCGCAGAGGGTGCTGTGGAGCCCGCAAACAGAGAGGGGTGAGCGCTGGCCGGGGGCAGGA
CACCGGCTGTCTAAGGGCTTGGTACCCAAGAGTCAGCCAGTGTGCAGAGGCGGCAGGCGGCACG
GCAGATTGATAAACTTATTTAGAAAGCATTGGTGGAAGGTTAAGGGCACAGCTCAGTGGCATTA
GTGGTAAACCACATGAAGCCCTGGCTTCTAGCCCCACCACACACACACAACATCGGTTAGGGGT
CTTCTCTGCACCGGGCATTATTCTAGCACTTAGGAAGAAGGCAGAGCAAACACAGTCCCTCACC
AGGGGAGAGACATAAAAAAAATCGACACAAGTGAATGCAGTATCCCAGGAGGTAAGTGTTAGAG
AAAATGAGAAAGTAGAATAGGGAAGCAGGGGGCGCGGGGAGGAGGCACGCCCTGGGTGGTCAGA
GAGGCGCTGGGGGCGTTTCAGTAAGTTGAGAGGCCTAGGGGAGAGCGCGGGGTGTGGGTGTCAG
GAGATCGCTCCGGGAGAGGACGGAAGGGCTCGAGCCTTGGACGCACAGGCCCCGGGGCAGCAAG
GGAACCGGCGCGGCCGAGCGGAGGGCCTGGAGGATCGGGCCGCGGCAGGACGGGCGGGGCGGCT
CCAGCTCGGAGGCGGCTCAGGCCGCTGCTCAGAGCGAAAGGGCAGCTTCCATCCTTCGCGGTTT
TGGGCAGAGCCATCACGTGCTCTGATTTGAGCTGCTGCCCTGAGAAGAGGCCTACTATGGCCAA
CGGAGGGTGACCAGCTCCTCCAGGCTCAGCTGGGACTTGCCGACTCTCAGCGTGGGAAGTCCGT
GCCTCGGGCTCTCCGGCAGGCCCCGCGGACTGGCAGGGGTGGTCACCCTGCTGGAGGACGAGCT
GCAAAACCAGCGAGGAGGCTCCCGCCGGTGTGCAGTAGGAGAGGAGGGACCCGGGAGCCGGGCA
GCTGGAGCAGGCCTGTGGGAAATGCTCGGATCTGAACAAGATGTGTGGCCGGCTGAGGCTGTTA
GAAAAGGACGAATCAGCGGGAGTCCAAGGTTTGCAGTTTCAGCAGCGAGGAGACAGCTGTCTTC
CGCCGAGGCAGAAGAAGGGGCTCAGTTCTCTGGCCGGAGTCTGGGGCAGTGGCCCTTCAGAAGC
TCCTCTGATCGATCGCCTTTCTCACACACTACCCCTGGGCAAACGCTCTGCGGGTATGGCCGGG
CATCCCCGAAGCCAGGAGCCCAGAGCGGAATGCCCGGGAAGGACGCAGACCCTGCGGCTCAAAG
CGAGAGGTCACCTCTGGGACAAGCCCTGAGAGGACTGCGCCAGTCCCTGTGAGGGCGACTGGCT
CGAGAGGCTGAGAACGGAAGCCCTGTGCCACCCTGGAGACAGACACCCCAGGTCCCCGCTGGGG
TCCCGCTTTGCCAGTCTGGCTGGTTGCTTGGGAATAATTGAAAGAATCTTCCAGCCCCTTAAAA
ATATGTTTTCTTAGAAATCCAAATGCCAATGGGTACCTCCAGGTCAGACCAGAGTCTCTGAGTT
TAAAAACTCACCCTTCTCCTCAAATACAAAAAGATGTTCCTGGCATTATGTTATGAAAAGTTGC
TAACAAGAATGGAGTAGCTGAATAGATTATGACACAACCGTCTGGTGGAGAAGTGTCAAGACTT
TGTTTCAACACAGCAAACTTAAAAACAAGCTGCCCCTTCCTCTTCTTGCCGCCCTTCCTGAGTT
GCCCGCCCCCAACTGGCTTGGTGGTGTTTTGCAGCGATGATACTCCACACGTGCCCGACGAGAA
GCTGGGAGAGGCGGCGGTGCTGGAAATCGTGGGACGTCTGACCAGCCTCATCAGGGAGGTCTTC
CCAGATACTAAAGTCTATGCTGCTATGGGAAATCACGACTTTCACCCCAAAAGCCAGTTCCCAG
CGAAGAGCAACAGTATCTACCATCAGGTAGCAGAACTGTGGAGACCCTGGCTTAGAAATGAATC
CGTCGCTCTCTTCAAAGAAGGTGCCTTCTATTCGGAGACGCTGCCGGGTGCCAGCAGCGCGCAC
CGCATCGTGGTGCTCAACACCAATCTCTACTACAGCAACAACCGGCTCACGGCGGACATAGCCG
ACCCCAGCCAGCAGTTCCAGTGGCTGGACGCTGTTCTGACCAACGCGTCCCAAGCAGGGGAGAA
GGTCTACATCATTGGCCACATACCCCCAGGGTTCTTCGAGAAGACGCGGGACAAGGCGTGGTTC
CGGAGTGGCTTCAACAAGGAGTACCTGAAGGCGGTCCGGAAGCACCACAGGGTCATAGCAGGGC
AGTTCTTCGGGCACCAGCACACTGACAGCTTTCGGATGTTCTACGACGACGCAGGAGCACCCAT
CAGCGTCATGTTCCTTGCCCCTGGGGTCACCCCGTGGAAAACCACGTTGGTTGGGGTGGTCAAC
GGCGCCAACAACCCCGGCATCCGGCTGTTCGAGTATGACCGAGCCACGCTGAGCCTGCAGGACA
TGATGACCTACTTCATGAACCTGAGCCAGGCGAATGCGCAGAACAACCCACGCTGGGAGCTCGA
GTACCGGCTGACTGAGGCCTATGGGGTGCCGGATGCCAGTGTCCGCTCCATGCAAGAGGTAGCG
ACTGGCATTGCTAGTGACCAGGACAAGCTGCAGCGCTACTACGATTACAACTCTGTGAGCTACG
ACACTACACCCTGTGGCGAGACCTGCCGGACGGAGTTCCTGTGTGCCATGCAGGAGGTGGACTT
CGACGCCTACTCCATCTGCCTGAGGAGCATGGGCGCCAGGCCCAGGATAGAGGTCCTGCTGGCG
CTGCTGGCCATGCTGCTGGGCCTGCAGGCTCTACTTGCACCCTGACCTTGGGCACCAACCTCTC
CTTGCGGGCGCATCTTCCTTCCAATAAATTGGGGCAGTGTCACCCCTCAAAAGCTGA

hide sequence

RefSeq Acc Id:

XM_013519539 ⟹ XP_013374993

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955452	7,114,749 - 7,138,924 (+)	NCBI

Sequence:

show sequence

GGCGCTTATACCACTGAGCTATATCCCAGGGCCCCTGTTTATTTTGATGGTGCAGTGAGTCAAA
CCCAAGGACTGACACATGCCAGACAAGTGCTTTACTACTGAGTCAGACCTCAGCCCCCTGCCAG
ATTATTTTGAAGCAAAGTACAGAGATCAGATCACCCTGTCCATACTCTTTCCATACATATGCCA
AAAAGAGAAAGGCTCTTTTTCTAACAGGCAGCACCTGGGGAGGCAGGTGCTGCTCGCGCGGAAG
AGTGCAAAGGTCTGCTGCCAGCGCCCTGCCCGGTGACCTCTCGGCGGCCCCGCGCCGCTCACAC
CCTGCTGGGAGAGGGAGAGAAGCCAGGGGAGCCGGCTTGGCGCATAGGTAGCAGGAAGTCCCGC
TCAGGCACGTGGCCGGCAGCAACTCCTTCCAAAACCTGCGGCGCAGAGGGAGGAACGGCTCCAG
AGGACAGATGGCTGCCGGGAGGGGCGCCCCGAGGATGAGGCCGCTGCTGTGGCCGATTTTCCTG
GCCGTCTGCGGAGTCTCCAGCGCCGCGCCAGCGATGATACTCCACACGTGCCCGACGAGAAGCT
GGGAGAGGCGGCGGTGCTGGAAATCGTGGGACGTCTGACCAGCCTCATCAGGGAGGTCTTCCCA
GATACTAAAGTCTATGCTGCTATGGGAAATCACGACTTTCACCCCAAAAGCCAGTTCCCAGCGA
AGAGCAACAGTATCTACCATCAGGTAGCAGAACTGTGGAGACCCTGGCTTAGAAATGAATCCGT
CGCTCTCTTCAAAGAAGGTGCCTTCTATTCGGAGACGCTGCCGGGTGCCAGCAGCGCGCACCGC
ATCGTGGTGCTCAACACCAATCTCTACTACAGCAACAACCGGCTCACGGCGGACATAGCCGACC
CCAGCCAGCAGTTCCAGTGGCTGGACGCTGTTCTGACCAACGCGTCCCAAGCAGGGGAGAAGGT
CTACATCATTGGCCACATACCCCCAGGGTTCTTCGAGAAGACGCGGGACAAGGCGTGGTTCCGG
AGTGGCTTCAACAAGGAGTACCTGAAGGCGGTCCGGAAGCACCACAGGGTCATAGCAGGGCAGT
TCTTCGGGCACCAGCACACTGACAGCTTTCGGATGTTCTACGACGACGCAGGAGCACCCATCAG
CGTCATGTTCCTTGCCCCTGGGGTCACCCCGTGGAAAACCACGTTGGTTGGGGTGGTCAACGGC
GCCAACAACCCCGGCATCCGGCTGTTCGAGTATGACCGAGCCACGCTGAGCCTGCAGGACATGA
TGACCTACTTCATGAACCTGAGCCAGGCGAATGCGCAGAACAACCCACGCTGGGAGCTCGAGTA
CCGGCTGACTGAGGCCTATGGGGTGCCGGATGCCAGTGTCCGCTCCATGCAAGAGGTAGCGACT
GGCATTGCTAGTGACCAGGACAAGCTGCAGCGCTACTACGATTACAACTCTGTGAGCTACGACA
CTACACCCTGTGGCGAGACCTGCCGGACGGAGTTCCTGTGTGCCATGCAGGAGGTGGACTTCGA
CGCCTACTCCATCTGCCTGAGGAGCATGGGCGCCAGGCCCAGGATAGAGGTCCTGCTGGCGCTG
CTGGCCATGCTGCTGGGCCTGCAGGCTCTACTTGCACCCTGACCTTGGGCACCAACCTCTCCTT
GCGGGCGCATCTTCCTTCCAATAAATTGGGGCAGTGTCACCCCTCAAAAGCTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005394993	(Get FASTA)	NCBI Sequence Viewer
	XP_013374992	(Get FASTA)	NCBI Sequence Viewer
	XP_013374993	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000017139
	ENSCLAP00000017139.1

RefSeq Acc Id:	XP_005394993 ⟸ XM_005394936
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2VKR2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAGRGAPRMRPLLWPIFLAVCGVSSAAPGRFWHISDLHLDPNYTVSQDPREVCPSAGSQLVHN AGPWGDYLCDSPWALINASIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVGRLTSLI REVFPDTKVYAAMGNHDFHPKSQFPAKSNSIYHQVAELWRPWLRNESVALFKEGAFYSETLPGA SSAHRIVVLNTNLYYSNNRLTADIADPSQQFQWLDAVLTNASQAGEKVYIIGHIPPGFFEKTRD KAWFRSGFNKEYLKAVRKHHRVIAGQFFGHQHTDSFRMFYDDAGAPISVMFLAPGVTPWKTTLV GVVNGANNPGIRLFEYDRATLSLQDMMTYFMNLSQANAQNNPRWELEYRLTEAYGVPDASVRSM QEVATGIASDQDKLQRYYDYNSVSYDTTPCGETCRTEFLCAMQEVDFDAYSICLRSMGARPRIE VLLALLAMLLGLQALLAP hide sequence

RefSeq Acc Id:

XP_013374993 ⟸ XM_013519539

- Peptide Label:

isoform X3

- Sequence:

show sequence

MGNHDFHPKSQFPAKSNSIYHQVAELWRPWLRNESVALFKEGAFYSETLPGASSAHRIVVLNTN
LYYSNNRLTADIADPSQQFQWLDAVLTNASQAGEKVYIIGHIPPGFFEKTRDKAWFRSGFNKEY
LKAVRKHHRVIAGQFFGHQHTDSFRMFYDDAGAPISVMFLAPGVTPWKTTLVGVVNGANNPGIR
LFEYDRATLSLQDMMTYFMNLSQANAQNNPRWELEYRLTEAYGVPDASVRSMQEVATGIASDQD
KLQRYYDYNSVSYDTTPCGETCRTEFLCAMQEVDFDAYSICLRSMGARPRIEVLLALLAMLLGL
QALLAP

hide sequence

RefSeq Acc Id:

XP_013374992 ⟸ XM_013519538

- Peptide Label:

isoform X2

- Sequence:

show sequence

MTQPSGGEVSRLCFNTANLKTSCPFLFLPPFLSCPPPTGLVVFCSDDTPHVPDEKLGEAAVLEI
VGRLTSLIREVFPDTKVYAAMGNHDFHPKSQFPAKSNSIYHQVAELWRPWLRNESVALFKEGAF
YSETLPGASSAHRIVVLNTNLYYSNNRLTADIADPSQQFQWLDAVLTNASQAGEKVYIIGHIPP
GFFEKTRDKAWFRSGFNKEYLKAVRKHHRVIAGQFFGHQHTDSFRMFYDDAGAPISVMFLAPGV
TPWKTTLVGVVNGANNPGIRLFEYDRATLSLQDMMTYFMNLSQANAQNNPRWELEYRLTEAYGV
PDASVRSMQEVATGIASDQDKLQRYYDYNSVSYDTTPCGETCRTEFLCAMQEVDFDAYSICLRS
MGARPRIEVLLALLAMLLGLQALLAP

hide sequence

RefSeq Acc Id:

ENSCLAP00000017139 ⟸ ENSCLAT00000017308

Protein Domains

Calcineurin-like phosphoesterase Sphingomyelin phosphodiesterase C-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000011768	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000017308	ENTREZGENE
	ENSCLAT00000017308.1	UniProtKB/TrEMBL
Gene3D-CATH	3.60.21.10	UniProtKB/TrEMBL
InterPro	ASM-like_Pdiesterase_prd	UniProtKB/TrEMBL
	ASM_C	UniProtKB/TrEMBL
	ASMase/PPN1_MPP	UniProtKB/TrEMBL
	Calcineurin-like_PHP_ApaH	UniProtKB/TrEMBL
	Metallo-depent_PP-like	UniProtKB/TrEMBL
NCBI Gene	Smpdl3b	ENTREZGENE
PANTHER	ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3B	UniProtKB/TrEMBL
	SPHINGOMYELIN PHOSPHODIESTERASE	UniProtKB/TrEMBL
Pfam	ASMase_C	UniProtKB/TrEMBL
	Metallophos	UniProtKB/TrEMBL
PIRSF	ASM-like_PDE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56300	UniProtKB/TrEMBL
UniProt	A0A8C2VKR2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Smpdl3b	sphingomyelin phosphodiesterase acid like 3B		sphingomyelin phosphodiesterase, acid-like 3B	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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