Dhx33 (DEAH-box helicase 33) - Rat Genome Database

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Gene: Dhx33 (DEAH-box helicase 33) Chinchilla lanigera
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Symbol: Dhx33
Name: DEAH-box helicase 33
RGD ID: 8968521
Description: ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); double-stranded RNA binding (ortholog); mRNA binding (ortholog); INVOLVED IN positive regulation of MAPK cascade (ortholog); positive regulation of NLRP3 inflammasome complex assembly (ortholog); positive regulation of transcription by RNA polymerase I (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 25 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); NLRP3 inflammasome complex (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DEAH (Asp-Glu-Ala-His) box polypeptide 33; putative ATP-dependent RNA helicase DHX33
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546710,793,934 - 10,818,898 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546710,797,464 - 10,819,083 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dhx33
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546710,793,934 - 10,818,898 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546710,797,464 - 10,819,083 (-)NCBIChiLan1.0ChiLan1.0
DHX33
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38175,440,917 - 5,468,982 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl175,440,917 - 5,468,982 (-)EnsemblGRCh38hg38GRCh38
GRCh37175,344,237 - 5,372,302 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36175,286,299 - 5,312,905 (-)NCBINCBI36Build 36hg18NCBI36
Build 34175,286,314 - 5,312,905NCBI
Celera175,361,948 - 5,388,553 (-)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef175,234,760 - 5,262,848 (-)NCBIHuRef
CHM1_1175,353,926 - 5,382,059 (-)NCBICHM1_1
T2T-CHM13v2.0175,334,655 - 5,362,725 (-)NCBIT2T-CHM13v2.0
Dhx33
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,874,917 - 70,895,258 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,874,917 - 70,895,263 (-)EnsemblGRCm39 Ensembl
GRCm381170,984,091 - 71,004,533 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,984,091 - 71,004,437 (-)EnsemblGRCm38mm10GRCm38
MGSCv371170,797,593 - 70,817,934 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,800,286 - 70,820,627 (-)NCBIMGSCv36mm8
Celera1178,538,505 - 78,558,847 (-)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1143.21NCBI
Dhx33
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81056,206,680 - 56,223,189 (-)NCBIGRCr8
mRatBN7.21055,708,102 - 55,724,618 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1055,705,756 - 55,724,567 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1060,387,811 - 60,404,254 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01059,876,330 - 59,892,773 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01055,375,420 - 55,391,863 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01057,622,022 - 57,638,485 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1057,622,022 - 57,638,485 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01057,367,234 - 57,383,697 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,889,929 - 57,906,392 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11057,904,115 - 57,934,844 (-)NCBI
Celera1054,853,790 - 54,870,250 (-)NCBICelera
Cytogenetic Map10q24NCBI
DHX33
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21913,051,397 - 13,079,461 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11715,019,627 - 15,047,677 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0175,490,642 - 5,517,192 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1175,484,093 - 5,508,927 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl175,484,093 - 5,508,926 (-)Ensemblpanpan1.1panPan2
DHX33
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1531,337,447 - 31,351,447 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl531,338,620 - 31,346,422 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha531,474,469 - 31,489,480 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0531,441,081 - 31,456,107 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl531,441,042 - 31,456,107 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1531,406,643 - 31,421,660 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0531,365,553 - 31,380,549 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0531,541,969 - 31,556,986 (+)NCBIUU_Cfam_GSD_1.0
Dhx33
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560253,530,788 - 53,555,817 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366772,345,315 - 2,364,802 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366772,345,153 - 2,367,247 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHX33
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1251,527,083 - 51,546,448 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11251,527,071 - 51,547,334 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DHX33
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1164,855,374 - 4,879,892 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605916,707,433 - 16,736,209 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dhx33
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247869,248,382 - 9,266,519 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247869,247,294 - 9,266,645 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000020878   ⟹   ENSCLAP00000020680
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546710,793,934 - 10,818,898 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000020879   ⟹   ENSCLAP00000020681
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546710,797,892 - 10,818,898 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000020880   ⟹   ENSCLAP00000020682
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546710,797,892 - 10,818,898 (-)Ensembl
RefSeq Acc Id: XM_005399647   ⟹   XP_005399704
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,797,464 - 10,819,083 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005399704 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000020680
  ENSCLAP00000020680.1
  ENSCLAP00000020681.1
  ENSCLAP00000020682.1
RefSeq Acc Id: XP_005399704   ⟸   XM_005399647
- UniProtKB: A0A8C2VUG5 (UniProtKB/TrEMBL),   A0A8C2YST5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000020682   ⟸   ENSCLAT00000020880
RefSeq Acc Id: ENSCLAP00000020680   ⟸   ENSCLAT00000020878
RefSeq Acc Id: ENSCLAP00000020681   ⟸   ENSCLAT00000020879

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014171 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020878 ENTREZGENE
  ENSCLAT00000020878.1 UniProtKB/TrEMBL
  ENSCLAT00000020879.1 UniProtKB/TrEMBL
  ENSCLAT00000020880.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1080 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAH_CS UniProtKB/TrEMBL
  DUF1605 UniProtKB/TrEMBL
  HA2_WH UniProtKB/TrEMBL
  Helicase-assoc_dom UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Dhx33 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE UniProtKB/TrEMBL
  ATP-DEPENDENT RNA HELICASE DHX33 UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  HA2 UniProtKB/TrEMBL
  HA2_C UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  OB_NTP_bind UniProtKB/TrEMBL
PROSITE DEAH_ATP_HELICASE UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HA2 UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C2VUG5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YST0_CHILA UniProtKB/TrEMBL
  A0A8C2YST5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Dhx33  DEAH-box helicase 33    DEAH (Asp-Glu-Ala-His) box polypeptide 33  Symbol and/or name change 5135510 APPROVED