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Gene: App (amyloid beta precursor protein) Chinchilla lanigera
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Symbol: App
Name: amyloid beta precursor protein
RGD ID: 8916289
Description: ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); apolipoprotein binding (ortholog); chaperone binding (ortholog); INVOLVED IN activation of MAPK activity (ortholog); activation of MAPKKK activity (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN glypican signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Alzheimer's disease 1 (ortholog); Alzheimer's Disease, Early-Onset, with Cerebral Amyloid Angiopathy (ortholog); FOUND IN amyloid-beta complex (ortholog); apical part of cell (ortholog); astrocyte projection (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Orthologs:
Homo sapiens (human) : APP (amyloid beta precursor protein)  HGNC  Alliance
Mus musculus (house mouse) : App (amyloid beta (A4) precursor protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : App (amyloid beta precursor protein)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : APP (amyloid beta precursor protein)
Canis lupus familiaris (dog) : APP (amyloid beta precursor protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : App (amyloid beta precursor protein)
Sus scrofa (pig) : APP (amyloid beta precursor protein)
Chlorocebus sabaeus (African green monkey) : APP (amyloid beta precursor protein)
Heterocephalus glaber (naked mole-rat) : App (amyloid beta precursor protein)
more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540725,722,849 - 25,974,268 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540725,725,259 - 25,973,582 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on App
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 8916289
Created: 2014-08-14
Species: Chinchilla lanigera
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.