Atat1 (alpha tubulin acetyltransferase 1)

Gene: Atat1 (alpha tubulin acetyltransferase 1) Chinchilla lanigera

Analyze

Symbol:

Atat1

Name:

alpha tubulin acetyltransferase 1

RGD ID:

8839589

Description:

ENCODES a protein that exhibits acetyltransferase activity (ortholog); lysine N-acetyltransferase activity, acting on acetyl phosphate as donor (ortholog); tubulin N-acetyltransferase activity (ortholog); INVOLVED IN dentate gyrus development (ortholog); microtubule cytoskeleton organization (ortholog); NLRP3 inflammasome complex assembly (ortholog); ASSOCIATED WITH Familial Prostate Cancer (ortholog); genetic disease (ortholog); High Myopia (ortholog); FOUND IN cytosol (ortholog); Golgi apparatus (ortholog); membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

alpha-tubulin N-acetyltransferase 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955583	643,575 - 652,393 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Familial Prostate Cancer (ISO)

genetic disease (ISO)

High Myopia (ISO)

megacolon (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

dentate gyrus development (ISO)

microtubule cytoskeleton organization (ISO)

NLRP3 inflammasome complex assembly (ISO)

positive regulation of NLRP3 inflammasome complex assembly (ISO)

regulation of fat cell differentiation (ISO)

response to mechanical stimulus (ISO)

response to pain (ISO)

spermatogenesis (ISO)

Cellular Component

cytosol (ISO)

Golgi apparatus (ISO)

membrane (ISO)

microtubule bundle (ISO)

mitotic spindle (ISO)

Molecular Function

acetyltransferase activity (ISO)

lysine N-acetyltransferase activity, acting on acetyl phosphate as donor (ISO)

protein binding (ISO)

tubulin N-acetyltransferase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Atat1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955583	643,575 - 652,393 (+)	NCBI	ChiLan1.0	ChiLan1.0

ATAT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	30,626,874 - 30,646,821 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	30,626,842 - 30,646,823 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	30,594,651 - 30,614,598 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	30,702,632 - 30,722,577 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	30,702,631 - 30,720,425	NCBI
Celera	6	32,192,731 - 32,212,715 (+)	NCBI		Celera
Cytogenetic Map	6	p21.33	NCBI
HuRef	6	30,394,781 - 30,414,765 (+)	NCBI		HuRef
CHM1_1	6	30,596,723 - 30,616,706 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	30,491,055 - 30,511,001 (+)	NCBI		T2T-CHM13v2.0

Atat1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	36,208,487 - 36,220,971 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	36,208,487 - 36,220,967 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	35,897,595 - 35,910,086 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	35,897,595 - 35,910,075 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	36,034,540 - 36,047,013 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	35,507,905 - 35,518,098 (-)	NCBI		MGSCv36	mm8
Celera	17	39,406,855 - 39,419,330 (-)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	18.75	NCBI

Atat1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	2,849,399 - 2,862,614 (+)	NCBI		GRCr8
mRatBN7.2	20	2,844,595 - 2,857,809 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	2,844,616 - 2,861,964 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	2,896,411 - 2,909,351 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	2,901,381 - 2,914,321 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	2,927,539 - 2,940,490 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	3,351,269 - 3,364,565 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	3,351,303 - 3,364,565 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	5,448,793 - 5,462,088 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	2,992,405 - 3,005,364 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	2,992,631 - 3,005,583 (+)	NCBI
Celera	20	270,616 - 283,574 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

ATAT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	45,184,291 - 45,207,174 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	41,147,482 - 41,170,398 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	30,368,847 - 30,391,595 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	31,238,771 - 31,261,795 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	31,238,778 - 31,261,611 (+)	Ensembl	panpan1.1		panPan2

ATAT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	441,847 - 456,349 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	441,895 - 456,152 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	579,489 - 593,991 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	586,158 - 599,574 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	586,171 - 599,379 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	442,543 - 457,251 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	511,819 - 526,707 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	581,863 - 595,374 (+)	NCBI		UU_Cfam_GSD_1.0

Atat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	33,935,469 - 33,954,419 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936837	300,715 - 319,623 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936837	300,765 - 319,742 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATAT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	23,173,447 - 23,185,458 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	23,173,138 - 23,185,463 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	26,895,036 - 26,907,375 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATAT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	41,807,405 - 41,830,670 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	41,807,291 - 41,830,000 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	30,320,597 - 30,343,906 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Atat1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	25,058,204 - 25,069,561 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	25,058,312 - 25,069,052 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013509800	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01075844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01075845	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCE01098162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01099542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_013509800 ⟹ XP_013365254

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955583	643,575 - 652,393 (+)	NCBI

Sequence:

show sequence

GGGCGGAAGTGACGTCGCGCGGGCGGGTCCGGCCGCGCACAATGGGCCATGGAGTTCCCTTTCG
ATGTGGACGCGCTGCTCCCGGAGCGGATCACCGTGCTGGACCAGCACCTGCGGCCCCCGGCCCG
CCGACCCGGAACCACAACGCCGGCCCGCGTTGACCTGCAGCAGCAAATCATGACCATTGTCGAT
GAGCTGGGCAAGGCTTCTGCCAAGGCCCAGCATCTTCCTGCCCCAATCACCAGTGCGTCAAGGA
TGCAGAGCAACCGCCACGTCATCTACGTGCTCAAAGACACTTCTGCCCGGCCGGCTGGGAAGGG
AGCCATTGTTGGTTTCCTCAAAGTTGGATACAAGAAGCTCTTTGTGCTGGATGACCGCGAGGCT
CACAATGAGGTGGAACCGCTCTGCATCCTGGACTTTTACATACACGAGTCCCTGCAGCGTCATG
GCCACGGGCGAGAGCTCTTCCAGTACATGCTGCAGAAGGAACGGGTTGAACCACATCAGCTGGC
CATTGACCGACCCTCACAGAAGCTGCTGAAGTTCCTGAATAAGCACTACAGCCTGGAGACCACA
GTCCCACAGGTGAACAACTTCGTGATCTTCGAAGGCTTCTTCGCGCATCAGCACCGGCCCCCCG
CCCCCTCTCTGAGGGCCTCGCGACTCTCCCGCGCCGCCGCCGAGCCCGCGCCCGCTGCTCCAGC
GCGGAAGCTGCCACCCAAGAGGGCCGAGGGCGACATTAAGCCGTACTCCTCCAGCGACCGGGAA
TTTCTGAAGGTCGCCGTGGAGCCCCCGTGGCCTCTGAACAGGGCCCCGCGCCGCGCCACCCCTG
CGGCGCACCCGCCCCCGCGCTCCAGCAGCCTGGGGAGCTCGCCCGAGCGCGGCCCGCTGCGCCC
CTTCGCGCCCGAGCAGGAGCTGCTGCGCTCCCTGCGCCTCTGCCCGCCGCACCCGACCGCCCGC
CTCCTGCTGGCCACCGACCCCGGGGGCAGCCCGGCGCAGCGCCGCCGGACCAGCTCCCTTCCCC
GCTCTGATGAGAGTCGATACTGACAGCCGCCCTCCCTCAGCGGCTCGGCCCCGCCTCCCTGCAT
CTTCCAGACCCAGTGGACCCTGTCGGAGCCGTGGGAGTGCTCTGCCCCTCTCAGACGGCTGGGT
CGTCAGGGTCCCACACGGCCTAGTACTGTAGCTTTTCTTAGCACCGAAGGGACCGCTGTTGGCC
CAGCCCGGGCTCTGTACTCTCCGCAGCCTGATCTGCCGCCAGACCCTGTGCTGGGCTGCGCAGA
GCATCTAGAGCAGCACGGGCTTGCCCATCAGACTGCCCCCGGGGAGGGTGAAGGCCTCTGCCAG
GGAGCCCCTGCGGGCGTCCTGCCCCCGGGTAATCCGTGTCCCCTCAGTCCTGCTCTGTGCTGCG
GCGTGAGCAAGCTCTGCCTCAGAGCAGCCCAGCTACACAGGACGGGCTCAGCGGCTCCCCAGTG
GGGTCCACTCACCGTTGCCAAACTTCACCCCCACGTTTGTGTCAGGGAGCCCCCACACTCGTTA
CACCACCACTTCTGCCAGACCCAGACTCGCTGAAGTTTAGTTCTGGCAGATCCCAGCAAACACC
GGGGTGTTCAGTTAGATCCTGGAACGCCCTGCAGTCCACCCCTGCCTGTGGCTCTGCTCACCCG
CTCCTGTCTGGTGAGACGTCTCGCGTGGGGTGGGCGCCAGTCCCCCCGGCCTGCCCTCCTCCCT
GGCCCTCACCCGTGCCCAGGGTCCAGACTGGCGTCGGCTCCCCGGCCCGGCCCCGCGTGTGTAG
ATCAGGCCCTCCCACCACACTCCCCGCGTCCTCGGGAGCAGGCTCTCCCTCTCTCCCCACTCAC
GCCTCCCTCTTCTTTCCCCCTCACTGTTGTCTGAATAAAGTGAATTCTTTCTGTGTTTTCTAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013365254	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000004830.1

RefSeq Acc Id:

XP_013365254 ⟸ XM_013509800

- Sequence:

show sequence

MEFPFDVDALLPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIVDELGKASAKAQHLPAPI
TSASRMQSNRHVIYVLKDTSARPAGKGAIVGFLKVGYKKLFVLDDREAHNEVEPLCILDFYIHE
SLQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYSLETTVPQVNNFVIFEGFFAH
QHRPPAPSLRASRLSRAAAEPAPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAP
RRATPAAHPPPRSSSLGSSPERGPLRPFAPEQELLRSLRLCPPHPTARLLLATDPGGSPAQRRR
TSSLPRSDESRY

hide sequence

Protein Domains

N-acetyltransferase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000003429	UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000004921.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.630.30	UniProtKB/TrEMBL
InterPro	Acyl_CoA_acyltransferase	UniProtKB/TrEMBL
	Atat	UniProtKB/TrEMBL
	GNAT_ATAT	UniProtKB/TrEMBL
NCBI Gene	LOC102004437	ENTREZGENE
PANTHER	ALPHA-TUBULIN N-ACETYLTRANSFERASE 1	UniProtKB/TrEMBL
	PTHR12327	UniProtKB/TrEMBL
Pfam	Acetyltransf_16	UniProtKB/TrEMBL
PROSITE	GNAT_ATAT	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55729	UniProtKB/TrEMBL
UniProt	A0A8C2UWT2_CHILA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	Atat1	alpha tubulin acetyltransferase 1	LOC102004437	collagen alpha-1(I) chain-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD