Slc15a3 (solute carrier family 15 member 3)

Advanced Search (OLGA)

Gene: Slc15a3 (solute carrier family 15 member 3) Chinchilla lanigera

Analyze

Symbol:

Slc15a3

Name:

solute carrier family 15 member 3

RGD ID:

8953922

Description:

ENCODES a protein that exhibits dipeptide transmembrane transporter activity (ortholog); peptidoglycan transmembrane transporter activity (ortholog); INVOLVED IN dipeptide import across plasma membrane (ortholog); peptidoglycan transport (ortholog); positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); intellectual disability (ortholog); leukocyte adhesion deficiency 3 (ortholog); FOUND IN endosome membrane (ortholog); intracellular membrane-bounded organelle (ortholog); lysosomal membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

solute carrier family 15 (oligopeptide transporter), member 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955511	5,574,840 - 5,582,307 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955511	5,574,686 - 5,582,992 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

intellectual disability (ISO)

leukocyte adhesion deficiency 3 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

dipeptide import across plasma membrane (ISO)

peptidoglycan transport (ISO)

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway (ISO)

Cellular Component

endosome membrane (ISO)

intracellular membrane-bounded organelle (ISO)

lysosomal membrane (ISO)

Molecular Function

dipeptide transmembrane transporter activity (ISO)

peptidoglycan transmembrane transporter activity (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Slc15a3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955511	5,574,840 - 5,582,307 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955511	5,574,686 - 5,582,992 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC15A3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	60,937,084 - 60,952,176 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	60,937,060 - 60,952,653 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	60,704,556 - 60,719,648 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	60,461,134 - 60,475,833 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	60,461,135 - 60,475,833	NCBI
Celera	11	58,065,442 - 58,080,124 (-)	NCBI		Celera
Cytogenetic Map	11	q12.2	NCBI
HuRef	11	57,050,724 - 57,065,416 (-)	NCBI		HuRef
CHM1_1	11	60,570,855 - 60,585,488 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	60,888,231 - 60,903,306 (-)	NCBI		T2T-CHM13v2.0

Slc15a3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	10,819,908 - 10,835,279 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	10,817,091 - 10,836,726 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	10,842,544 - 10,857,915 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	10,839,727 - 10,859,362 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	10,917,034 - 10,932,405 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	10,909,589 - 10,924,948 (+)	NCBI		MGSCv36	mm8
Celera	19	11,535,605 - 11,550,983 (+)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	7.23	NCBI

Slc15a3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	216,906,836 - 216,932,046 (+)	NCBI		GRCr8
mRatBN7.2	1	207,492,365 - 207,507,158 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	207,492,365 - 207,507,157 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	215,867,205 - 215,881,996 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	222,927,770 - 222,942,588 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	215,621,593 - 215,636,384 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	226,896,387 - 226,912,644 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	226,897,625 - 226,912,708 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	233,963,402 - 233,978,193 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	213,341,322 - 213,356,103 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	213,499,751 - 213,514,532 (+)	NCBI
Celera	1	204,984,950 - 204,999,742 (+)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

SLC15A3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	62,106,337 - 62,121,515 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	63,150,381 - 63,165,578 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	56,200,278 - 56,215,451 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	59,640,834 - 59,655,144 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	59,640,970 - 59,655,535 (-)	Ensembl	panpan1.1		panPan2

SLC15A3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	55,354,987 - 55,363,672 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	53,928,148 - 53,936,956 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	56,403,606 - 56,412,382 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	18	55,460,980 - 55,469,748 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	55,082,563 - 55,091,327 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	55,963,727 - 55,972,508 (+)	NCBI		UU_Cfam_GSD_1.0

Slc15a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	11,871,196 - 11,883,099 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936581	1,984,344 - 1,996,924 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936581	1,985,062 - 1,996,924 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC15A3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	10,800,503 - 10,814,389 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	10,799,927 - 10,814,363 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	10,352,005 - 10,366,583 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC15A3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	12,896,612 - 12,910,740 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	12,895,982 - 12,912,214 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	110,264,616 - 110,279,317 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc15a3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624926	294,376 - 303,248 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624926	294,263 - 303,326 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005408288	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01066571	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01066572	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDI01323373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01315022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000006530 ⟹ ENSCLAP00000006424

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955511	5,574,840 - 5,582,307 (-)	Ensembl

RefSeq Acc Id:

XM_005408288 ⟹ XP_005408345

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955511	5,574,686 - 5,582,992 (-)	NCBI

Sequence:

show sequence

GGAGGACCAGGGAGGACAGAGGTCAGAGGAGCACCGGGGAGGGCAGGGGCGGACCAGGGAGAGA
CAGGAGGTCAGAGGAGCACCGGGGAGGACAGAGGAAGGCCGGGAAAGTTGAGAGAGGCCCAGGG
GGACAGGGGAGGCCCGGGCAGTCCAGGGAAGGCCGGGGAGGCCGCGATGCCCCGGGCCGAGGAG
CGGCGGCCGCTGGTGGCCCGGGCCGGCGTGTGGCGGCGGCGCGCGGCGTGTGCGGCGGTGCTGG
CGGTGCAGGCGCTGGAGCGCGCCGCCTTCCTGGGCGTGGCGCCCACGCTGGTGCTGCGCCTGGG
CGGGCTGGGCTGGGCGGACGCGCAGGCCTCGCTCGCCGCGCTGCTGTTCCTCGGCGCCTCCTTC
GTGCTGGCCCCGCTGGGCGGCTGGACGGCCGACGCCTACCTGGGCCGGCGCCGCGCGCTGGTGC
TCAGCCTCGGCCTCTACCTGCCGGGCCTGGGGCTGCTGCTGGCCTCGGCCGGCGACGACGCCCG
CCTGGCGCTGTGCGGAGACATGCGCGCCGCCCCGCTGCGCCCCGTGCACGCGCGCGCGCCTCCT
CCCGGCCCCTACTGCGCGGCCCCGCTCTACGGCGCGCTCCTGCTGACCGCGCTGGCCGCCAGCT
CCGCGCGCGTGAACCTCGCTGCCTTCGGGGCCGACCAGGTGAGGGATCTGGGCCGCGACGCCAC
CCGCCGCTTCTTCAACTGGTTCTACTGGAGCGTGAACGTGGGGGCCGTGTTTGCGCTGCTGGTG
GTGGCCTTCGTCCAGCAGAACATCGACTTCCTGCTGGGCTACAGCCTCCCGCTGGGCTGTGTGT
CCCTGGCCTTCTTCATCTTCCTCTTCGCCACCCCGGCTTTCATCTCCAAGCCCCCCATGGGCAG
CCAGGTGTCCTCCATGCTCAAGCTCGCTCTCCGGGGCTGCTGCCCCTGGCTGCGGCGACCACGC
TCCGCCAGGCACCCCCAAGGTGTCCATCTGCTGCCTGACCAGAGGGTTCCCCAGCCCGGTCCTT
CCCCGCAGGAAGACGTTGCCAACTTCCAGGTGCTGGTGAAGATCCTGCCCGTCATGGCGACCCT
GGTGCCCTACTGGATGGTGTACTTCCAGATGCAGTCCACCTACGTCCTGCAAGGCCTGCGTCTG
CACATCCCCAGGCTCTTCCCCACCAGCCCCACCAACACGTCCGCGGTCCTGAGGGCCTGGGCCA
GCGACTACACGATCCCGGAAGCCTGGCTCCTGCTGGCCAATGTGGTGGCCGTGCTCATCCTGGT
CCCCCTGAAGGACCACCTGCTGGACCCCCTGCTGCTACGCTGCCAGCTGCTCCCCTCGGCCCTG
CAGAAGATGGCCCTGGGCATGTTCTTCGGCTTCACCTCTGTCGTCGTTGCAGGGGTCCTGGAGA
CGGAGCGCTTGCGGTATGTCCACCGCAACGAGACCGTGCCCCAGGTGATCGGGAAGGACCTGCA
CTGGGCCGCGCCACTGTCCATCTGGTGGCAGATCCCCCAGTACCTGCTCATCGGCATCAGTGAG
ATCTTTGCCAGCATCCCAGGCCTGGAGTTTGCCTATGGGGCAGCGCCGCGCACCATGCAGAGCG
CCATCCTCGGCATCTTCTTCTGCCTGTCGGGCCTGGGCTCGCTGCTGGGCTCCGGCCTCGTGGC
TGTGCTGTCCCTGCCGGGGGGCTGGATGTACTGCCCCACGGACGCTGGGAACGGCCGCAGCTGC
CGCATGGACCTCTACTTCTTCCTGCTGGCCGGCATCCAGGCTGTCACGGCTGCGCTGTTCATCT
GGATCGCGCAGCGCTACGAGAGCACACGGCAGGGCTCGGCCCCTCGGCCAGGCCCACCCACGCC
AGGGCTCACCTCGCCCCCGCGCACCCGCACCCGGGACACAGATAGCAGCAGGGCCAGCCCGCGT
GGCACCTTCTGAGTTTATTCTGGACCCAACGTGGAACGCGTTGGTTCCCATAAATAAGGGAGCC
CTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005408345	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000006424
	ENSCLAP00000006424.1

RefSeq Acc Id:

XP_005408345 ⟸ XM_005408288

- Sequence:

show sequence

MPRAEERRPLVARAGVWRRRAACAAVLAVQALERAAFLGVAPTLVLRLGGLGWADAQASLAALL
FLGASFVLAPLGGWTADAYLGRRRALVLSLGLYLPGLGLLLASAGDDARLALCGDMRAAPLRPV
HARAPPPGPYCAAPLYGALLLTALAASSARVNLAAFGADQVRDLGRDATRRFFNWFYWSVNVGA
VFALLVVAFVQQNIDFLLGYSLPLGCVSLAFFIFLFATPAFISKPPMGSQVSSMLKLALRGCCP
WLRRPRSARHPQGVHLLPDQRVPQPGPSPQEDVANFQVLVKILPVMATLVPYWMVYFQMQSTYV
LQGLRLHIPRLFPTSPTNTSAVLRAWASDYTIPEAWLLLANVVAVLILVPLKDHLLDPLLLRCQ
LLPSALQKMALGMFFGFTSVVVAGVLETERLRYVHRNETVPQVIGKDLHWAAPLSIWWQIPQYL
LIGISEIFASIPGLEFAYGAAPRTMQSAILGIFFCLSGLGSLLGSGLVAVLSLPGGWMYCPTDA
GNGRSCRMDLYFFLLAGIQAVTAALFIWIAQRYESTRQGSAPRPGPPTPGLTSPPRTRTRDTDS
SRASPRGTF

hide sequence

Ensembl Acc Id:

ENSCLAP00000006424 ⟸ ENSCLAT00000006530

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000004538	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000006530	ENTREZGENE
	ENSCLAT00000006530.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1250.20	UniProtKB/TrEMBL
InterPro	MFS_trans_sf	UniProtKB/TrEMBL
	POT_fam	UniProtKB/TrEMBL
NCBI Gene	Slc15a3	ENTREZGENE
PANTHER	PTHR11654	UniProtKB/TrEMBL
	SOLUTE CARRIER FAMILY 15 MEMBER 3	UniProtKB/TrEMBL
Pfam	PTR2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF103473	UniProtKB/TrEMBL
UniProt	A0A8C2V1K7_CHILA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Slc15a3	solute carrier family 15 member 3		solute carrier family 15 (oligopeptide transporter), member 3	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD