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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of kinase activity
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Accession:GO:0033673 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
Synonyms:exact_synonym: down regulation of kinase activity;   downregulation of kinase activity
 narrow_synonym: inhibition of kinase activity;   kinase inhibitor


show annotations for term's descendants           Sort by:
negative regulation of kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AJUBA ajuba LIM protein acts_upstream_of_or_within ISO (PMID:15870270) MGI PMID:15870270 NCBI chr14:3,791,309...3,802,763
Ensembl chr14:21,889,443...21,900,700 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B involved_in ISO (PMID:19170105) UniProt PMID:19170105 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in ISO (PMID:19170105) UniProt PMID:19170105 NCBI chr11:2,908,537...2,911,134 JBrowse link
G CSK C-terminal Src kinase ISO RGD PMID:10411542 RGD:5134371 NCBI chr15:53,724,814...53,745,710
Ensembl chr15:73,342,703...73,363,476 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ISO RGD PMID:19762078 RGD:150429972 NCBI chr 1:138,048,730...138,200,426
Ensembl chr 1:141,932,158...141,990,766 		JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:10490622) UniProt PMID:10490622 NCBI chr 1:220,450,218...220,461,412
Ensembl chr 1:225,817,899...225,842,031 		JBrowse link
G IRS2 insulin receptor substrate 2 involved_in ISO (PMID:19523444) BHF-UCL PMID:19523444 NCBI chr13:90,886,095...90,917,724 JBrowse link
G LOC100995589 uncharacterized LOC100995589 involved_in ISO (PMID:24391509) UniProt PMID:24391509 NCBI chr2A:15,923,366...15,926,680 JBrowse link
G MSTN myostatin involved_in ISO (PMID:19357233) CACAO PMID:19357233 NCBI chr2B:77,364,927...77,452,426
Ensembl chr2B:195,283,903...195,290,922 		JBrowse link
G NPRL2 NPR2 like, GATOR1 complex subunit involved_in ISO (PMID:18616680) UniProt PMID:18616680 NCBI chr 3:50,273,611...50,277,175
Ensembl chr 3:51,508,932...51,512,776 		JBrowse link
G PRDX3 peroxiredoxin 3 involved_in ISO (PMID:18205602) UniProt PMID:18205602 NCBI chr10:115,738,346...115,749,482
Ensembl chr10:119,162,714...119,173,845 		JBrowse link
G PRPSAP1 phosphoribosyl pyrophosphate synthetase associated protein 1 ISO RGD PMID:9366267 RGD:5134981 NCBI chr17:70,258,663...70,302,287
Ensembl chr17:75,810,423...75,853,442 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 ISO due to an autoinhibitory domain RGD PMID:15081430 RGD:2298791 NCBI chr12:825,659...985,016
Ensembl chr12:791,153...944,602 		JBrowse link
negative regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKIA cAMP-dependent protein kinase inhibitor alpha acts_upstream_of_or_within ISO (PMID:7905001) MGI PMID:7905001 NCBI chr 8:75,046,316...75,136,264
Ensembl chr 8:76,734,210...76,766,673 		JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta acts_upstream_of_or_within ISO (PMID:7905001) MGI PMID:7905001 NCBI chr 6:120,373,497...120,517,119
Ensembl chr 6:124,612,910...124,640,260 		JBrowse link
G PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha involved_in ISO (PMID:22674394) AgBase PMID:22674394 NCBI chr 3:48,665,421...48,774,111
Ensembl chr 3:49,747,611...49,854,382 		JBrowse link
negative regulation of cyclin-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:8876165) CAFA PMID:8876165 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B involved_in ISO (PMID:8684460) CAFA PMID:8684460 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in ISO (PMID:11746698) CAFA PMID:11746698 NCBI chr11:2,908,537...2,911,134 JBrowse link
negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway involved_in ISO (PMID:8521819) UniProt PMID:8521819 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709 		JBrowse link
G CASP3 caspase 3 acts_upstream_of_or_within ISO (PMID:12970760) MGI PMID:12970760 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185 		JBrowse link
G CDK5RAP1 CDK5 regulatory subunit associated protein 1 involved_in ISO (PMID:11882646) UniProt PMID:11882646 NCBI chr20:29,648,003...29,690,210
Ensembl chr20:30,762,967...30,804,237 		JBrowse link
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 ISO RGD PMID:10721722 RGD:632478 NCBI chr 9:91,519,179...91,707,469
Ensembl chr 9:119,868,015...120,055,608 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 ISO RGD PMID:10721722 RGD:632478 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (PMID:12130539) MGI PMID:12130539 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B involved_in
acts_upstream_of_or_within		 ISO (PMID:28666995)
(PMID:12130539)		 RGD
UniProt
MGI		 PMID:12130539 PMID:22584582 PMID:28666995 RGD:10045364 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A acts_upstream_of_or_within
involved_in		 ISO (PMID:12130539)
(PMID:7739547)
(PMID:8259215)		 MGI
BHF-UCL		 PMID:7739547 PMID:8259215 PMID:12130539 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C acts_upstream_of_or_within ISO (PMID:7739547) MGI PMID:7739547 NCBI chr 1:50,214,767...50,221,465
Ensembl chr 1:51,704,528...51,718,374 		JBrowse link
G FBXO7 F-box protein 7 acts_upstream_of_or_within ISO (PMID:21652635) MGI PMID:21652635 NCBI chr22:13,481,255...13,505,301
Ensembl chr22:31,335,423...31,359,224 		JBrowse link
G HEXIM2 HEXIM P-TEFb complex subunit 2 involved_in ISO (PMID:15713662) HGNC-UCL PMID:15713662 NCBI chr17:12,157,392...12,167,281
Ensembl chr17:12,333,957...12,343,399 		JBrowse link
G HHEX hematopoietically expressed homeobox involved_in ISO (PMID:12554669) BHF-UCL PMID:12554669 NCBI chr10:89,433,402...89,439,137
Ensembl chr10:92,947,373...92,952,992 		JBrowse link
G INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of_or_within ISO (PMID:21540187) MGI PMID:21540187 NCBI chr17:5,036,659...5,046,146
Ensembl chr17:5,024,740...5,034,216 		JBrowse link
G KAT2B lysine acetyltransferase 2B involved_in ISO (PMID:19773423) UniProt PMID:19773423 NCBI chr 3:19,956,067...20,070,637
Ensembl chr 3:20,286,865...20,400,770 		JBrowse link
G LATS2 large tumor suppressor kinase 2 involved_in ISO (PMID:12853976) UniProt PMID:12853976 NCBI chr13:2,300,625...2,389,027
Ensembl chr13:20,611,861...20,683,083 		JBrowse link
G MEN1 menin 1 involved_in ISO (PMID:15640349) UniProt PMID:15640349 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164 		JBrowse link
G MYOCD myocardin involved_in ISO (PMID:18451334) BHF-UCL PMID:18451334 NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659 		JBrowse link
G NR2F2 nuclear receptor subfamily 2 group F member 2 involved_in ISO (PMID:19210544) BHF-UCL PMID:19210544 NCBI chr15:75,008,879...75,021,981 JBrowse link
G PLK1 polo like kinase 1 involved_in ISO (PMID:21041660) BHF-UCL PMID:21041660 NCBI chr16:14,420,972...14,432,821
Ensembl chr16:23,928,773...23,940,779 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:21241890) BHF-UCL PMID:21241890 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605 		JBrowse link
G TFAP4 transcription factor AP-4 involved_in ISO (PMID:18818310) UniProt PMID:18818310 NCBI chr16:3,176,129...3,226,404
Ensembl chr16:4,348,929...4,368,525 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in ISO (PMID:15962316) BHF-UCL PMID:15962316 NCBI chr 6:135,617,465...135,634,085
Ensembl chr 6:139,705,255...139,720,819 		JBrowse link
G WEE2 WEE2 oocyte meiosis inhibiting kinase involved_in ISO (PMID:21454751) UniProt PMID:21454751 NCBI chr 7:133,635,359...133,663,153
Ensembl chr 7:146,110,121...146,132,872 		JBrowse link
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBLC Cbl proto-oncogene C involved_in ISO (PMID:10362357) BHF-UCL PMID:10362357 NCBI chr19:41,726,272...41,748,829 JBrowse link
G CHMP6 charged multivesicular body protein 6 involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr17:75,415,055...75,423,279
Ensembl chr17:81,144,837...81,151,962 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in ISO PMID:17599051
(PMID:18046415)
(PMID:16648858)		 UniProt PMID:16648858 PMID:17599051 PMID:18046415 RGD:8553726 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674 		JBrowse link
G GPRC5A G protein-coupled receptor class C group 5 member A involved_in ISO (PMID:25744720) UniProt PMID:25744720 NCBI chr12:12,905,682...12,928,596
Ensembl chr12:13,282,865...13,305,727 		JBrowse link
G PSEN1 presenilin 1 involved_in ISO (PMID:20208556) BHF-UCL PMID:20208556 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (PMID:20208556) BHF-UCL PMID:20208556 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G SOCS4 suppressor of cytokine signaling 4 involved_in ISO (PMID:15590694) UniProt PMID:15590694 NCBI chr14:35,614,238...35,636,531
Ensembl chr14:53,904,783...53,906,105 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) UniProt PMID:15590694 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041 		JBrowse link
G TSG101 tumor susceptibility 101 involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr11:18,518,110...18,564,814
Ensembl chr11:18,189,868...18,248,149 		JBrowse link
G VPS25 vacuolar protein sorting 25 homolog involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr17:14,538,322...14,544,573
Ensembl chr17:14,763,523...14,769,672 		JBrowse link
G ZFYVE28 zinc finger FYVE-type containing 28 involved_in ISO (PMID:19460345) UniProt PMID:19460345 NCBI chr 4:2,412,659...2,564,741
Ensembl chr 4:2,320,446...2,470,638 		JBrowse link
G ZGPAT zinc finger CCCH-type and G-patch domain containing involved_in ISO (PMID:19644445) UniProt PMID:19644445 Ensembl chr20:61,630,271...61,662,967 JBrowse link
negative regulation of glucokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCKR glucokinase regulator acts_upstream_of_or_within
involved_in		 ISO (PMID:10713097)
(PMID:23621087)		 MGI
UniProt		 PMID:10713097 PMID:23621087 NCBI chr2A:27,497,938...27,530,650
Ensembl chr2A:27,587,077...27,613,927 		JBrowse link
G LOC100976343 cytochrome c oxidase assembly protein COX11, mitochondrial acts_upstream_of_or_within ISO (PMID:17069463) MGI PMID:17069463 NCBI chr17:49,009,099...49,058,145
Ensembl chr17:53,915,841...53,923,431 		JBrowse link
G MIDN midnolin acts_upstream_of_or_within ISO PMID:24187134 MGI PMID:24187134 RGD:8655525
G PRKN parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within ISO (PMID:24187134) MGI PMID:24187134 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
negative regulation of hexokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCKR glucokinase regulator ISO RGD PMID:14627435 RGD:1598592 NCBI chr2A:27,497,938...27,530,650
Ensembl chr2A:27,587,077...27,613,927 		JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIDA axin interactor, dorsalization associated acts_upstream_of_or_within ISO (PMID:17681137) MGI PMID:17681137 NCBI chr 1:198,341,375...198,385,682 JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 involved_in ISO (PMID:24512202) UniProt PMID:24512202 NCBI chr 9:32,800,077...32,814,745
Ensembl chr 9:33,608,502...33,622,275 		JBrowse link
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within
involved_in		 ISO (PMID:15306813)
(PMID:10391943)		 MGI
BHF-UCL		 PMID:10391943 PMID:15306813 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720 		JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (PMID:11959862) BHF-UCL PMID:11959862 NCBI chr2B:70,347,712...70,371,852
Ensembl chr2B:188,157,061...188,178,266 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664) BHF-UCL PMID:16636664 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472 		JBrowse link
G HIPK3 homeodomain interacting protein kinase 3 involved_in ISO (PMID:11034606) UniProt PMID:11034606 NCBI chr11:33,230,731...33,330,617
Ensembl chr11:33,114,534...33,212,783 		JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISO PMID:21076496 RGD
UniProt		 PMID:12064607 PMID:21076496 RGD:1299562 RGD:13673827 NCBI chr11:45,839,754...45,860,615
Ensembl chr11:46,332,159...46,352,010 		JBrowse link
G NPPA natriuretic peptide A involved_in ISO (PMID:22399583) UniProt PMID:22399583 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23991106) UniProt PMID:23991106 NCBI chr 1:88,685,736...88,743,164
Ensembl chr 1:123,734,511...123,790,830 		JBrowse link
G SFRP1 secreted frizzled related protein 1 acts_upstream_of_or_within ISO (PMID:19300477) MGI PMID:19300477 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within ISO (PMID:19300477) MGI PMID:19300477 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258 		JBrowse link
G SFRP5 secreted frizzled related protein 5 acts_upstream_of_or_within ISO (PMID:19300477) MGI PMID:19300477 NCBI chr10:94,383,269...94,389,053
Ensembl chr10:97,877,790...97,882,850 		JBrowse link
negative regulation of MAP kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISO (PMID:19460854) UniProt PMID:19460854 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885 		JBrowse link
G AGT angiotensinogen involved_in ISO (PMID:28283184) CACAO PMID:28283184 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G APOE apolipoprotein E involved_in ISO (PMID:9685360) BHF-UCL PMID:9685360 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G CAV1 caveolin 1 acts_upstream_of_or_within ISO (PMID:12388746) MGI PMID:12388746 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655 		JBrowse link
G CBLC Cbl proto-oncogene C involved_in ISO (PMID:10362357) BHF-UCL PMID:10362357 NCBI chr19:41,726,272...41,748,829 JBrowse link
G CD300A CD300a molecule involved_in ISO (PMID:16254138) UniProt PMID:16254138 NCBI chr17:68,403,647...68,426,285
Ensembl chr17:73,965,008...73,983,928 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:21283629) UniProt PMID:21283629 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:12813029)
(PMID:20154697)		 BHF-UCL PMID:12813029 PMID:20154697 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336 		JBrowse link
G DEFB114 defensin beta 114 involved_in ISO (PMID:23482568) UniProt PMID:23482568 NCBI chr 6:49,527,541...49,531,451
Ensembl chr 6:50,787,203...50,791,015 		JBrowse link
G DUSP1 dual specificity phosphatase 1 involved_in ISO (PMID:7593328) UniProt PMID:7593328 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960 		JBrowse link
G DUSP7 dual specificity phosphatase 7 involved_in ISO (PMID:9788880) UniProt PMID:9788880 NCBI chr 3:51,990,115...51,997,627
Ensembl chr 3:53,219,167...53,226,491 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:17182785 RGD:2301767 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (PMID:11408560) BHF-UCL PMID:11408560 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase acts_upstream_of_or_within ISO (PMID:12409258), (PMID:16271875) MGI PMID:12409258 PMID:16271875 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785 		JBrowse link
G HYAL2 hyaluronidase 2 involved_in ISO (PMID:12676986) UniProt PMID:12676986 NCBI chr 3:50,243,926...50,248,972
Ensembl chr 3:51,479,020...51,482,551 		JBrowse link
G IL1B interleukin 1 beta involved_in ISO (PMID:16865359) BHF-UCL PMID:16865359 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:12556481) UniProt PMID:12556481 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373 		JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 ISO RGD PMID:12933696 RGD:1626126 NCBI chr11:67,302,066...67,317,785
Ensembl chr11:70,527,017...70,540,846 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in ISO (PMID:17379480) BHF-UCL PMID:17379480 NCBI chr12:22,661,613...22,721,203
Ensembl chr12:23,168,346...23,227,148 		JBrowse link
G LOC100973655 protein fem-1 homolog A acts_upstream_of_or_within ISO (PMID:18270204) MGI PMID:18270204 NCBI chr21:468,156...495,596
Ensembl chr19:4,763,674...4,765,683 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:9252121) UniProt PMID:9252121 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287 		JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (PMID:11297510)
(PMID:12409258), (PMID:16271875)
(PMID:10620616)		 MGI PMID:10620616 PMID:11297510 PMID:12409258 PMID:16271875 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295 		JBrowse link
G NUP62 nucleoporin 62 involved_in ISO (PMID:11489947) UniProt PMID:11489947 NCBI chr19:46,919,731...46,942,318 JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 acts_upstream_of_or_within ISO (PMID:17724343) MGI PMID:17724343 NCBI chr 4:45,255,403...45,279,319
Ensembl chr 4:51,102,305...51,123,506 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (PMID:22045810) CACAO PMID:22045810 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421 		JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:9857190 RGD:10044039 NCBI chr11:18,758,285...18,822,845
Ensembl chr11:18,673,366...18,711,885 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (PMID:9064344), (PMID:9254656) MGI PMID:9064344 PMID:9254656 NCBI chr12:7,075,879...7,093,041
Ensembl chr12:6,991,099...7,008,830 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in ISO (PMID:12833140)
(PMID:19494114)		 UniProt PMID:12833140 PMID:19494114 NCBI chr11:47,941,134...48,130,538
Ensembl chr11:48,613,761...48,670,494 		JBrowse link
G RGS14 regulator of G protein signaling 14 involved_in ISO (PMID:20837545) UniProt PMID:20837545 NCBI chr 5:172,659,323...172,674,084
Ensembl chr 5:179,721,876...179,739,453 		JBrowse link
G RGS2 regulator of G protein signaling 2 involved_in ISO (PMID:19127022) BHF-UCL PMID:19127022 NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 acts_upstream_of_or_within ISO (PMID:16339969) MGI PMID:16339969 NCBI chr 4:115,570,788...115,578,824
Ensembl chr 4:126,718,811...126,719,770 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 acts_upstream_of_or_within ISO (PMID:16339969) MGI PMID:16339969 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408 		JBrowse link
G SPRY4 sprouty RTK signaling antagonist 4 acts_upstream_of_or_within ISO (PMID:16339969) MGI PMID:16339969 NCBI chr 5:137,667,280...137,683,578
Ensembl chr 5:143,778,785...143,791,939 		JBrowse link
G STK38 serine/threonine kinase 38 involved_in ISO (PMID:17906693) UniProt PMID:17906693 NCBI chr 6:36,056,585...36,110,531
Ensembl chr 6:37,255,183...37,308,102 		JBrowse link
G TSC2 TSC complex subunit 2 ISO RGD PMID:14612383 RGD:1580517 NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 involved_in ISO (PMID:19477270) BHF-UCL PMID:19477270 NCBI chr 4:35,580,755...35,592,314
Ensembl chr 4:41,428,759...41,440,129 		JBrowse link
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF4A hepatocyte nuclear factor 4 alpha ISO RGD PMID:16584384 RGD:1625011 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536 		JBrowse link
negative regulation of protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO in PC12 cells, PKCzeta deactivated after long-term activation of Adora2a RGD PMID:12590138 RGD:1625697 NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in ISO PMID:8524413
(PMID:9373175)		 BHF-UCL PMID:8524413 PMID:9373175 RGD:8554844 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G AKT1S1 AKT1 substrate 1 involved_in ISO (PMID:17386266) UniProt PMID:17386266 NCBI chr19:46,882,073...46,890,404
Ensembl chr19:55,797,927...55,806,256 		JBrowse link
G CAV3 caveolin 3 acts_upstream_of_or_within ISO (PMID:14600260) MGI PMID:14600260 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (PMID:22496641) UniProt PMID:22496641 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739 		JBrowse link
G CEP43 centrosomal protein 43 involved_in ISO (PMID:17888034) UniProt PMID:17888034 NCBI chr 6:164,969,391...165,011,935
Ensembl chr 6:169,945,218...169,988,027 		JBrowse link
G CEP85 centrosomal protein 85 involved_in ISO (PMID:26220856) UniProt PMID:26220856 NCBI chr 1:25,495,228...25,539,857
Ensembl chr 1:26,562,744...26,607,852 		JBrowse link
G CHP1 calcineurin like EF-hand protein 1 involved_in ISO PMID:12966074 UniProt PMID:12966074 RGD:8553340 NCBI chr15:20,172,874...20,223,382
Ensembl chr15:38,418,815...38,467,681 		JBrowse link
G DAXX death domain associated protein ISO RGD PMID:17289031 RGD:9587773 NCBI chr 6:32,890,846...32,895,307
Ensembl chr 6:34,004,543...34,008,717 		JBrowse link
G DBNDD2 dysbindin domain containing 2 involved_in ISO (PMID:16618118) UniProt PMID:16618118 NCBI chr20:41,738,913...41,743,520
Ensembl chr20:42,829,178...42,833,333 		JBrowse link
G DEPTOR DEP domain containing MTOR interacting protein involved_in ISO (PMID:19446321) UniProt PMID:19446321 NCBI chr 8:116,563,935...116,743,843
Ensembl chr 8:119,311,942...119,492,127 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:15601829) UniProt PMID:15601829 NCBI chr16:3,351,825...3,381,914
Ensembl chr16:4,519,965...4,550,786 		JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:12688394 RGD:1581394 NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257 		JBrowse link
G DRD5 dopamine receptor D5 ISO RGD PMID:12688394 RGD:1581394 NCBI chr 4:4,189,536...4,193,144
Ensembl chr 4:9,509,094...9,510,527 		JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (PMID:11959862) BHF-UCL PMID:11959862 NCBI chr2B:70,347,712...70,371,852
Ensembl chr2B:188,157,061...188,178,266 		JBrowse link
G EPHA1 EPH receptor A1 involved_in ISO (PMID:19118217) UniProt PMID:19118217 NCBI chr 7:135,385,894...135,403,632
Ensembl chr 7:147,875,363...147,892,745 		JBrowse link
G EPHB2 EPH receptor B2 acts_upstream_of ISO (PMID:11585923) ARUK-UCL PMID:11585923 NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118 		JBrowse link
G FABP4 fatty acid binding protein 4 acts_upstream_of_or_within ISO (PMID:15684432) MGI PMID:15684432 NCBI chr 8:78,001,476...78,006,006
Ensembl chr 8:79,624,899...79,630,168 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha acts_upstream_of_or_within ISO (PMID:12124778) MGI PMID:12124778 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188 		JBrowse link
G GADD45B growth arrest and DNA damage inducible beta acts_upstream_of_or_within ISO (PMID:12124778) MGI PMID:12124778 NCBI chr19:1,489,263...1,491,391
Ensembl chr19:2,451,837...2,453,992 		JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma acts_upstream_of_or_within ISO (PMID:12124778) MGI PMID:12124778 NCBI chr 9:60,695,307...60,696,860
Ensembl chr 9:88,740,411...88,741,958 		JBrowse link
G GSKIP GSK3B interacting protein involved_in ISO (PMID:16981698) UniProt PMID:16981698 NCBI chr14:76,993,055...77,017,142
Ensembl chr14:96,329,936...96,339,378 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664) RGD
BHF-UCL		 PMID:16636664 PMID:21668448 RGD:10401931 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 involved_in ISO (PMID:15731106) BHF-UCL PMID:15731106 NCBI chr 7:67,716,021...67,717,762
Ensembl chr 7:82,751,523...82,752,984 		JBrowse link
G IL6 interleukin 6 ISO Phospholamban phosphorylation RGD PMID:15845578 RGD:2306941 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G ILK integrin linked kinase ISO GSK-3 activity as a Tau protein kinase RGD PMID:12629168 RGD:2302091 NCBI chr11:6,735,735...6,742,922
Ensembl chr11:6,418,717...6,425,788 		JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:12556481) UniProt PMID:12556481 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373 		JBrowse link
G ITGB1BP1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) UniProt PMID:20616313 NCBI chr2A:9,396,553...9,413,408
Ensembl chr2A:9,556,857...9,577,155 		JBrowse link
G LOC100986730 guanine nucleotide-binding protein G(q) subunit alpha involved_in ISO (PMID:20399743) BHF-UCL PMID:20399743 NCBI chr 9:46,816,409...47,129,116
Ensembl chr 9:76,575,815...76,773,849 		JBrowse link
G MLLT1 MLLT1 super elongation complex subunit acts_upstream_of_or_within ISO (PMID:11007757) MGI PMID:11007757 NCBI chr19:5,231,481...5,301,160
Ensembl chr19:6,156,365...6,216,779 		JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (PMID:17053831)
(PMID:16835260)		 MGI PMID:16835260 PMID:17053831 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor acts_upstream_of_or_within ISO (PMID:16405865)
(PMID:14580336)		 MGI PMID:14580336 PMID:16405865 NCBI chr22:10,648,022...10,738,167
Ensembl chr22:28,454,119...28,544,013 		JBrowse link
G PCP4 Purkinje cell protein 4 ISO RGD PMID:10751438 RGD:1579763 NCBI chr21:26,069,039...26,284,247
Ensembl chr21:39,587,400...39,618,734 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:9373175) BHF-UCL PMID:9373175 NCBI chr16:1,394,447...1,463,735 JBrowse link
G PKIA cAMP-dependent protein kinase inhibitor alpha acts_upstream_of_or_within ISO (PMID:9218452) MGI PMID:9218452 NCBI chr 8:75,046,316...75,136,264
Ensembl chr 8:76,734,210...76,766,673 		JBrowse link
G PKIG cAMP-dependent protein kinase inhibitor gamma acts_upstream_of_or_within ISO (PMID:9218452) MGI PMID:9218452 NCBI chr20:40,861,694...40,949,756
Ensembl chr20:42,039,676...42,049,064 		JBrowse link
G PKN1 protein kinase N1 acts_upstream_of_or_within ISO (PMID:23223530) MGI PMID:23223530 NCBI chr19:13,996,454...14,035,272
Ensembl chr19:14,846,463...14,879,205 		JBrowse link
G PLEC plectin involved_in ISO (PMID:12200133) MGI PMID:12200133 NCBI chr 8:140,681,252...140,742,753
Ensembl chr 8:143,674,696...143,712,433 		JBrowse link
G PPIA peptidylprolyl isomerase A involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545 		JBrowse link
G PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E involved_in ISO (PMID:11864573) UniProt PMID:11864573 NCBI chr17:52,832,291...53,057,157
Ensembl chr17:57,874,629...57,903,205 		JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in ISO (PMID:11864573) UniProt PMID:11864573 NCBI chr22:4,039,032...4,072,165
Ensembl chr22:20,520,022...20,553,128 		JBrowse link
G PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 involved_in ISO (PMID:17255938) BHF-UCL PMID:17255938 NCBI chr 7:143,143,556...143,463,492
Ensembl chr 7:155,293,748...155,610,078 		JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha acts_upstream_of_or_within ISO (PMID:18316483) MGI PMID:18316483 NCBI chr17:62,448,718...62,488,493
Ensembl chr17:67,838,484...67,877,943 		JBrowse link
G PRKCA protein kinase C alpha acts_upstream_of_or_within ISO (PMID:11923480) MGI PMID:11923480 NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903 		JBrowse link
G PRKRIP1 PRKR interacting protein 1 acts_upstream_of_or_within ISO (PMID:12679338) MGI PMID:12679338 NCBI chr 7:94,515,712...94,567,066
Ensembl chr13:24,723,062...24,734,122 		JBrowse link
G PSEN1 presenilin 1 acts_upstream_of_or_within ISO (PMID:12805290) MGI PMID:12805290 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in ISO (PMID:9197241)
(PMID:10970857)		 UniProt PMID:9197241 PMID:10970857 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994 		JBrowse link
G QARS1 glutaminyl-tRNA synthetase 1 involved_in ISO (PMID:11096076) CAFA PMID:11096076 NCBI chr 3:49,020,310...49,029,443
Ensembl chr 3:50,100,216...50,125,112 		JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in ISO (PMID:9858607) UniProt PMID:9858607 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575 		JBrowse link
G RGN regucalcin ISO RGD PMID:11455566 RGD:9590207 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881 		JBrowse link
G RTRAF RNA transcription, translation and transport factor involved_in ISO (PMID:15147888) UniProt PMID:15147888 NCBI chr14:32,589,078...32,604,286
Ensembl chr14:50,874,274...50,889,493 		JBrowse link
G SH3BP5 SH3 domain binding protein 5 involved_in ISO (PMID:10339589) UniProt PMID:10339589 NCBI chr 3:15,180,369...15,257,951
Ensembl chr 3:15,517,447...15,594,971 		JBrowse link
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO (PMID:23528453) MGI PMID:23528453 NCBI chr 9:37,768,566...37,921,897 JBrowse link
G SMYD3 SET and MYND domain containing 3 acts_upstream_of_or_within ISO (PMID:23752591) MGI PMID:23752591 NCBI chr 1:221,371,348...222,125,774
Ensembl chr 1:226,737,960...227,481,191 		JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in ISO (PMID:18216281) ARUK-UCL PMID:18216281 NCBI chr15:17,182,976...17,286,566
Ensembl chr15:35,439,762...35,536,565 		JBrowse link
G TAF7 TATA-box binding protein associated factor 7 involved_in ISO (PMID:18391197) UniProt PMID:18391197 NCBI chr 5:136,680,554...136,682,862 JBrowse link
G THY1 Thy-1 cell surface antigen involved_in ISO PMID:15093746 UniProt PMID:15093746 RGD:8553684 NCBI chr11:114,253,535...114,259,495
Ensembl chr11:118,180,717...118,186,901 		JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in ISO (PMID:15299019) BHF-UCL PMID:15299019 NCBI chr 8:122,115,194...122,123,319
Ensembl chr 8:124,867,359...124,872,924 		JBrowse link
G TRIB3 tribbles pseudokinase 3 involved_in ISO (PMID:12791994) BHF-UCL
UniProt		 PMID:12791994 NCBI chr20:583,267...605,416
Ensembl chr20:359,879...375,486 		JBrowse link
G TRIM27 tripartite motif containing 27 involved_in ISO (PMID:22128329) UniProt PMID:22128329 NCBI chr 6:28,722,505...28,743,484
Ensembl chr 6:29,390,423...29,411,308 		JBrowse link
G TSC2 TSC complex subunit 2 acts_upstream_of_or_within ISO (PMID:15249583) MGI PMID:15249583 NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569 		JBrowse link
G UBASH3B ubiquitin associated and SH3 domain containing B acts_upstream_of_or_within ISO (PMID:27609517)
(PMID:20585042)		 MGI PMID:20585042 PMID:27609517 NCBI chr11:117,489,411...117,647,719
Ensembl chr11:121,410,545...121,563,133 		JBrowse link
G WARS1 tryptophanyl-tRNA synthetase 1 involved_in ISO (PMID:22504299) CAFA PMID:22504299 NCBI chr14:80,954,852...80,996,316
Ensembl chr14:100,268,845...100,310,662 		JBrowse link
G WNK4 WNK lysine deficient protein kinase 4 involved_in ISO (PMID:30765526) MGI PMID:30765526 NCBI chr17:14,520,448...14,537,799
Ensembl chr17:14,746,365...14,762,423 		JBrowse link
G WWTR1 WW domain containing transcription regulator 1 involved_in ISO (PMID:20412773) BHF-UCL PMID:20412773 NCBI chr 3:146,536,564...146,678,847
Ensembl chr 3:154,114,034...154,254,490 		JBrowse link
negative regulation of protein kinase activity by regulation of protein phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific involved_in ISO (PMID:19651874)
(PMID:18362360)		 UniProt PMID:18362360 PMID:19651874 NCBI chr 1:129,937,993...129,983,747 JBrowse link
G ADARB1 adenosine deaminase RNA specific B1 involved_in ISO (PMID:21289159) UniProt PMID:21289159 NCBI chr21:31,374,841...31,532,721
Ensembl chr21:44,715,931...44,815,748 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:21283629) UniProt PMID:21283629 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302 		JBrowse link
G CORO1C coronin 1C involved_in ISO (PMID:19913511) UniProt PMID:19913511 NCBI chr12:106,220,755...106,306,098
Ensembl chr12:109,617,093...109,674,368 		JBrowse link
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO (PMID:23977283) MGI PMID:23977283 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 acts_upstream_of_or_within ISO (PMID:20418913) MGI PMID:20418913 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674 		JBrowse link
G NPM1 nucleophosmin 1 involved_in ISO (PMID:12882984) UniProt PMID:12882984 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656 		JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in ISO (PMID:15140879) UniProt PMID:15140879 NCBI chr22:4,039,032...4,072,165
Ensembl chr22:20,520,022...20,553,128 		JBrowse link
G PTEN phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:20418913) MGI PMID:20418913 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605 		JBrowse link
negative regulation of protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:11121037) BHF-UCL PMID:11121037 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:19223857) UniProt PMID:19223857 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:20154697)
(PMID:19903888)		 BHF-UCL PMID:19903888 PMID:20154697 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336 		JBrowse link
G DTNBP1 dystrobrevin binding protein 1 acts_upstream_of_or_within ISO (PMID:25297099) MGI PMID:25297099 NCBI chr 6:15,377,263...15,523,317
Ensembl chr 6:15,741,698...15,887,256 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha involved_in ISO (PMID:23329839) CACAO PMID:23329839 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188 		JBrowse link
G LOC100974858 core histone macro-H2A.1 involved_in ISO (PMID:22194607) UniProt PMID:22194607 NCBI chr 5:130,727,065...130,791,932
Ensembl chr 5:136,868,521...136,933,834 		JBrowse link
G LRP5 LDL receptor related protein 5 involved_in ISO (PMID:19107203) BHF-UCL PMID:19107203 NCBI chr11:63,396,511...63,534,471
Ensembl chr11:66,735,246...66,839,817 		JBrowse link
G LRP6 LDL receptor related protein 6 involved_in ISO (PMID:19107203) BHF-UCL PMID:19107203 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973 		JBrowse link
G PRKCH protein kinase C eta involved_in ISO (PMID:34593629) UniProt PMID:34593629 NCBI chr14:41,882,022...42,151,305
Ensembl chr14:60,179,081...60,408,251 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in ISO (PMID:12486103) UniProt PMID:12486103 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in ISO PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 acts_upstream_of_or_within ISO (PMID:29274751) ARUK-UCL PMID:29274751 NCBI chr2A:40,169,339...40,586,546
Ensembl chr2A:40,939,900...41,363,038 		JBrowse link
G SLC8A3 solute carrier family 8 member A3 acts_upstream_of_or_within ISO (PMID:29274751) ARUK-UCL PMID:29274751 NCBI chr14:50,634,091...50,779,712 JBrowse link
G TESK1 testis associated actin remodelling kinase 1 involved_in ISO PMID:18216281 ARUK-UCL PMID:18216281 RGD:13461749 NCBI chr 9:35,456,965...35,461,736
Ensembl chr 9:36,258,902...36,264,545 		JBrowse link
negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GGNBP2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO (PMID:26764350) MGI PMID:26764350 NCBI chr17:20,491,687...20,537,516
Ensembl chr17:20,786,936...20,831,055 		JBrowse link
G HYAL2 hyaluronidase 2 involved_in ISO (PMID:12676986) UniProt PMID:12676986 NCBI chr 3:50,243,926...50,248,972
Ensembl chr 3:51,479,020...51,482,551 		JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:16493035)
(PMID:9151699)		 ARUK-UCL PMID:9151699 PMID:16493035 NCBI chr19:51,606,681...51,612,751 JBrowse link
G MVP major vault protein involved_in ISO (PMID:16441665) UniProt PMID:16441665 Ensembl chr16:30,190,090...30,219,070 JBrowse link
G PTK6 protein tyrosine kinase 6 involved_in ISO (PMID:15539407) UniProt PMID:15539407 Ensembl chr20:61,453,386...61,462,951 JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (PMID:21216966) ParkinsonsUK-UCL PMID:21216966 NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570 		JBrowse link
G SRCIN1 SRC kinase signaling inhibitor 1 involved_in ISO (PMID:17525734) UniProt PMID:17525734 NCBI chr17:18,666,094...18,742,015
Ensembl chr17:18,942,084...19,015,744 		JBrowse link
negative regulation of Rho-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHORDC1 cysteine and histidine rich domain containing 1 involved_in ISO (PMID:20230755) UniProt PMID:20230755 NCBI chr11:85,170,779...85,193,659
Ensembl chr11:88,668,179...88,689,378 		JBrowse link
G HEG1 heart development protein with EGF like domains 1 involved_in ISO (PMID:26780829) UniProt PMID:26780829 NCBI chr 3:122,091,832...122,204,436
Ensembl chr 3:128,969,817...129,028,317 		JBrowse link
G RASIP1 Ras interacting protein 1 involved_in ISO (PMID:26780829) UniProt PMID:26780829 NCBI chr19:45,720,179...45,740,131 JBrowse link
negative regulation of tau-protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RB1 RB transcriptional corepressor 1 involved_in ISO PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575 		JBrowse link
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP4 acid phosphatase 4 involved_in ISO (PMID:15219672) UniProt PMID:15219672 NCBI chr19:47,754,780...47,760,294
Ensembl chr19:56,649,018...56,653,909 		JBrowse link
G DUSP10 dual specificity phosphatase 10 involved_in ISO (PMID:10391943) BHF-UCL PMID:10391943 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720 		JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in ISO (PMID:28759036) BHF-UCL PMID:28759036 NCBI chr17:13,618,860...13,631,743
Ensembl chr17:13,784,594...13,797,045 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (PMID:23639442) BHF-UCL PMID:23639442 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421 		JBrowse link
G PTPRB protein tyrosine phosphatase receptor type B involved_in ISO (PMID:26063811) CACAO PMID:26063811 NCBI chr12:68,025,973...68,147,613
Ensembl chr12:70,797,843...70,915,308 		JBrowse link
G PTPRH protein tyrosine phosphatase receptor type H involved_in ISO (PMID:26063811) CACAO PMID:26063811 NCBI chr19:52,221,813...52,249,218
Ensembl chr19:60,917,749...60,943,528 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in ISO (PMID:26063811) CACAO PMID:26063811 NCBI chr11:47,941,134...48,130,538
Ensembl chr11:48,613,761...48,670,494 		JBrowse link
G PTPRO protein tyrosine phosphatase receptor type O involved_in ISO (PMID:26063811) CACAO PMID:26063811 NCBI chr12:15,329,314...15,594,787
Ensembl chr12:15,725,917...15,990,532 		JBrowse link
G PTPRT protein tyrosine phosphatase receptor type T involved_in ISO (PMID:24846175) ARUK-UCL PMID:24846175 NCBI chr20:38,399,267...39,526,776
Ensembl chr20:39,502,794...40,317,701 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    biological regulation 11629
      regulation of molecular function 1716
        regulation of catalytic activity 1157
          regulation of transferase activity 579
            negative regulation of transferase activity 206
              negative regulation of kinase activity 187
                negative regulation of hexokinase activity + 4
                negative regulation of lipid kinase activity 0
                negative regulation of protein kinase activity + 172
Path 2
Term Annotations click to browse term
  biological_process 16644
    biological regulation 11629
      regulation of biological process 11252
        regulation of cellular process 10895
          regulation of metabolic process 6441
            negative regulation of metabolic process 3029
              negative regulation of phosphorus metabolic process 370
                negative regulation of phosphate metabolic process 370
                  negative regulation of phosphorylation 320
                    negative regulation of kinase activity 187
                      negative regulation of hexokinase activity + 4
                      negative regulation of lipid kinase activity 0
                      negative regulation of protein kinase activity + 172
paths to the root