CEACAM1 (CEA cell adhesion molecule 1) - Rat Genome Database
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Gene: CEACAM1 (CEA cell adhesion molecule 1) Pan paniscus
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Symbol: CEACAM1
Name: CEA cell adhesion molecule 1
RGD ID: 11818561
Description: ENCODES a protein that exhibits actin binding (ortholog); bile acid transmembrane transporter activity (ortholog); calmodulin binding (ortholog); INVOLVED IN bile acid and bile salt transport (ortholog); blood vessel development (ortholog); calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); Lung Neoplasms (ortholog); schizophrenia (ortholog); FOUND IN adherens junction (ortholog); apical plasma membrane (ortholog); basal plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11947,987,522 - 48,008,739 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01939,395,550 - 39,417,063 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
bile acid and bile salt transport  (ISO)
blood vessel development  (ISO)
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules  (ISO)
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules  (ISO)
cell adhesion  (ISO)
cell-cell adhesion via plasma-membrane adhesion molecules  (ISO)
cell-cell junction organization  (ISO)
cellular response to insulin stimulus  (ISO)
common myeloid progenitor cell proliferation  (ISO)
granulocyte colony-stimulating factor signaling pathway  (ISO)
homophilic cell adhesion via plasma membrane adhesion molecules  (ISO)
insulin catabolic process  (ISO)
insulin receptor internalization  (ISO)
negative regulation by host of viral genome replication  (ISO)
negative regulation by host of viral process  (ISO)
negative regulation of bone resorption  (ISO)
negative regulation of cytokine production  (ISO)
negative regulation of cytotoxic T cell degranulation  (ISO)
negative regulation of fatty acid biosynthetic process  (ISO)
negative regulation of granulocyte differentiation  (ISO)
negative regulation of hepatocyte proliferation  (ISO)
negative regulation of interleukin-1 production  (ISO)
negative regulation of interleukin-2 production  (ISO)
negative regulation of JNK cascade  (ISO)
negative regulation of lipid biosynthetic process  (ISO)
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target  (ISO)
negative regulation of osteoclast differentiation  (ISO)
negative regulation of platelet aggregation  (ISO)
negative regulation of protein kinase activity  (ISO)
negative regulation of T cell mediated cytotoxicity  (ISO)
negative regulation of T cell proliferation  (ISO)
negative regulation of T cell receptor signaling pathway  (ISO)
negative regulation of vascular permeability  (ISO)
Peyer's patch development  (ISO)
positive regulation by host of viral process  (ISO)
positive regulation of activation-induced cell death of T cells  (ISO)
positive regulation of calcineurin-NFAT signaling cascade  (ISO)
positive regulation of CD4-positive, alpha-beta T cell activation  (ISO)
positive regulation of CD4-positive, alpha-beta T cell proliferation  (ISO)
positive regulation of CD8-positive, alpha-beta T cell activation  (ISO)
positive regulation of homophilic cell adhesion  (ISO)
positive regulation of immunoglobulin production  (ISO)
positive regulation of JNK cascade  (ISO)
positive regulation of MAP kinase activity  (ISO)
positive regulation of T cell proliferation  (ISO)
positive regulation of vasculogenesis  (ISO)
regulation of blood vessel remodeling  (ISO)
regulation of cell growth  (ISO)
regulation of cell migration  (ISO)
regulation of endothelial cell differentiation  (ISO)
regulation of endothelial cell migration  (ISO)
regulation of epidermal growth factor receptor signaling pathway  (ISO)
regulation of ERK1 and ERK2 cascade  (ISO)
regulation of homophilic cell adhesion  (ISO)
regulation of phosphatidylinositol 3-kinase signaling  (ISO)
regulation of sprouting angiogenesis  (ISO)
signal transduction  (ISO)
viral entry into host cell  (ISO)
wound healing, spreading of cells  (ISO)

References

Genomics

Comparative Map Data
CEACAM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11947,987,522 - 48,008,739 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01939,395,550 - 39,417,063 (-)NCBIMhudiblu_PPA_v0panPan3
CEACAM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1942,507,304 - 42,561,234 (-)EnsemblGRCh38hg38GRCh38
GRCh381942,507,306 - 42,528,482 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371943,011,458 - 43,032,633 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,703,298 - 47,724,479 (-)NCBINCBI36hg18NCBI36
Build 341947,703,298 - 47,724,438NCBI
Celera1939,812,240 - 39,833,442 (-)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1939,441,679 - 39,462,877 (-)NCBIHuRef
CHM1_11943,013,129 - 43,034,353 (-)NCBICHM1_1
Ceacam1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39725,161,127 - 25,177,072 (-)NCBIGRCm39mm39
GRCm39 Ensembl725,161,132 - 25,177,028 (-)Ensembl
GRCm38725,461,702 - 25,477,647 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,461,707 - 25,477,603 (-)EnsemblGRCm38mm10GRCm38
MGSCv37726,246,721 - 26,262,644 (-)NCBIGRCm37mm9NCBIm37
MGSCv36725,170,462 - 25,186,385 (-)NCBImm8
Celera720,077,172 - 20,093,096 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.84NCBI
Ceacam1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2181,043,595 - 81,060,050 (-)NCBI
Rnor_6.0 Ensembl182,327,955 - 82,344,345 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0182,327,955 - 82,344,345 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0183,589,574 - 83,605,846 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,742,540 - 80,758,943 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1180,822,590 - 80,837,016NCBI
Celera175,484,279 - 75,500,669 (-)NCBICelera
RH 3.4 Map1826.0RGD
Cytogenetic Map1q21NCBI
Ceacam1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955555426,894 - 446,235 (+)NCBIChiLan1.0ChiLan1.0
CEACAM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1111,745,413 - 111,917,830 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11111,902,429 - 111,919,191 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ceacam1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493670637,480 - 53,306 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CEACAM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1649,437,308 - 49,460,614 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,330,417 - 45,353,721 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CEACAM1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,708,368 - 36,731,729 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_008964144   ⟹   XP_008962392
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11947,987,522 - 48,008,739 (-)NCBI
Mhudiblu_PPA_v01939,395,550 - 39,417,063 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008964148   ⟹   XP_008962396
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11947,989,430 - 48,008,739 (-)NCBI
Mhudiblu_PPA_v01939,395,550 - 39,417,063 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008964149   ⟹   XP_008962397
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11947,987,522 - 48,008,739 (-)NCBI
Mhudiblu_PPA_v01939,395,550 - 39,417,063 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008964150   ⟹   XP_008962398
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11947,989,292 - 48,008,739 (-)NCBI
Mhudiblu_PPA_v01939,397,644 - 39,417,063 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034946104   ⟹   XP_034801995
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01939,400,206 - 39,417,063 (-)NCBI
RefSeq Acc Id: XM_034946105   ⟹   XP_034801996
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01939,400,206 - 39,417,063 (-)NCBI
RefSeq Acc Id: XM_034946107   ⟹   XP_034801998
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01939,395,550 - 39,417,063 (-)NCBI
RefSeq Acc Id: XM_034946108   ⟹   XP_034801999
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01939,407,551 - 39,417,063 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_008962397   ⟸   XM_008964149
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008962392   ⟸   XM_008964144
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008962398   ⟸   XM_008964150
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008962396   ⟸   XM_008964148
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_034801998   ⟸   XM_034946107
- Peptide Label: isoform X7
RefSeq Acc Id: XP_034801996   ⟸   XM_034946105
- Peptide Label: isoform X4
RefSeq Acc Id: XP_034801995   ⟸   XM_034946104
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034801999   ⟸   XM_034946108
- Peptide Label: isoform X8
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034140 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000021898 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000021917 UniProtKB/TrEMBL
  ENSPPAP00000021919 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000044702 UniProtKB/TrEMBL
  ENSPPAT00000044721 UniProtKB/TrEMBL
  ENSPPAT00000044723 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
NCBI Gene CEACAM1 ENTREZGENE
Pfam Ig_2 UniProtKB/TrEMBL
  PF00047 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A2R9AX86_PANPA UniProtKB/TrEMBL
  A0A2R9AXH5_PANPA UniProtKB/TrEMBL
  A0A2R9AXT6_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-27 CEACAM1  CEA cell adhesion molecule 1  CEACAM1  carcinoembryonic antigen related cell adhesion molecule 1  Symbol and/or name change 5135510 APPROVED