PTPRO (protein tyrosine phosphatase receptor type O) - Rat Genome Database
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Gene: PTPRO (protein tyrosine phosphatase receptor type O) Pan paniscus
Analyze
Symbol: PTPRO
Name: protein tyrosine phosphatase receptor type O
RGD ID: 11988831
Description: ENCODES a protein that exhibits cadherin binding (ortholog); protein homodimerization activity (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN axon guidance (ortholog); cell morphogenesis (ortholog); glomerular visceral epithelial cell differentiation (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Experimental Liver Cirrhosis (ortholog); Liver Neoplasms (ortholog); FOUND IN apical plasma membrane (ortholog); dendritic spine (ortholog); GABA-ergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: receptor-type tyrosine-protein phosphatase O
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11215,725,447 - 15,990,532 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1215,725,917 - 15,990,532 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01215,329,314 - 15,594,787 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
PTPRO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11215,725,447 - 15,990,532 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1215,725,917 - 15,990,532 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01215,329,314 - 15,594,787 (+)NCBIMhudiblu_PPA_v0panPan3
PTPRO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1215,322,257 - 15,602,175 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1215,322,508 - 15,598,331 (+)EnsemblGRCh38hg38GRCh38
GRCh381215,322,334 - 15,598,331 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371215,475,442 - 15,751,265 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361215,366,754 - 15,641,602 (+)NCBINCBI36hg18NCBI36
Build 341215,590,552 - 15,641,602NCBI
Celera1220,620,432 - 20,895,225 (+)NCBI
Cytogenetic Map12p12.3NCBI
HuRef1215,244,485 - 15,520,600 (+)NCBIHuRef
CHM1_11215,441,256 - 15,717,221 (+)NCBICHM1_1
Ptpro
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396137,229,189 - 137,441,632 (+)NCBIGRCm39mm39
GRCm39 Ensembl6137,229,317 - 137,440,231 (+)Ensembl
GRCm386137,252,299 - 137,464,634 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6137,252,319 - 137,463,233 (+)EnsemblGRCm38mm10GRCm38
MGSCv376137,200,820 - 137,413,155 (+)NCBIGRCm37mm9NCBIm37
MGSCv366137,216,661 - 137,427,429 (+)NCBImm8
Celera6140,313,708 - 140,529,181 (+)NCBICelera
Cytogenetic Map6G1NCBI
Ptpro
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24170,164,071 - 170,374,790 (+)NCBI
Rnor_6.0 Ensembl4171,250,818 - 171,461,677 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04171,250,766 - 171,461,571 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04235,507,823 - 235,718,691 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44174,376,396 - 174,586,694 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14174,621,519 - 174,831,818 (+)NCBI
Celera4158,744,680 - 158,954,298 (+)NCBICelera
Cytogenetic Map4q43-q44NCBI
Ptpro
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541312,018,888 - 12,248,807 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541312,019,026 - 12,248,026 (+)NCBIChiLan1.0ChiLan1.0
PTPRO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2731,084,544 - 31,322,022 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12731,082,334 - 31,322,024 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ptpro
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365871,967,079 - 2,188,651 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl557,019,745 - 57,263,346 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1557,021,819 - 57,263,395 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2560,237,424 - 60,286,938 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRO
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11115,225,375 - 15,494,559 (+)NCBI
ChlSab1.1 Ensembl1115,392,926 - 15,495,807 (+)Ensembl
Ptpro
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475222,446,203 - 22,700,925 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000048673   ⟹   ENSPPAP00000025843
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1215,725,917 - 15,988,196 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000048687   ⟹   ENSPPAP00000025857
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1215,877,240 - 15,990,532 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000048689   ⟹   ENSPPAP00000025859
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1215,877,256 - 15,988,180 (+)Ensembl
RefSeq Acc Id: XM_003816526   ⟹   XP_003816574
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11215,725,447 - 15,990,532 (+)NCBI
Mhudiblu_PPA_v01215,329,314 - 15,594,787 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003816527   ⟹   XP_003816575
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11215,725,447 - 15,990,532 (+)NCBI
Mhudiblu_PPA_v01215,329,314 - 15,594,787 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003816574 (Get FASTA)   NCBI Sequence Viewer  
  XP_003816575 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003816574   ⟸   XM_003816526
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003816575   ⟸   XM_003816527
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000025857   ⟸   ENSPPAT00000048687
RefSeq Acc Id: ENSPPAP00000025859   ⟸   ENSPPAT00000048689
RefSeq Acc Id: ENSPPAP00000025843   ⟸   ENSPPAT00000048673
Protein Domains
Fibronectin type-III   TYR_PHOSPHATASE_2   Tyrosine-protein phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036045 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000025843 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000025857 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000025859 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000048673 UniProtKB/TrEMBL
  ENSPPAT00000048687 UniProtKB/TrEMBL
  ENSPPAT00000048689 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTPase_domain UniProtKB/TrEMBL
  PTPRO UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
KEGG Report pps:100980526 UniProtKB/TrEMBL
NCBI Gene PTPRO ENTREZGENE
PANTHER PTHR47028 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A2R9B8C3_PANPA UniProtKB/TrEMBL
  A0A2R9B8D0_PANPA UniProtKB/TrEMBL
  A0A2R9B9U0_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 PTPRO  protein tyrosine phosphatase receptor type O    protein tyrosine phosphatase, receptor type O  Symbol and/or name change 5135510 APPROVED