DUSP19 (dual specificity phosphatase 19) - Rat Genome Database

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Gene: DUSP19 (dual specificity phosphatase 19) Pan paniscus
Analyze
Symbol: DUSP19
Name: dual specificity phosphatase 19
RGD ID: 11943400
Description: ENCODES a protein that exhibits MAP-kinase scaffold activity (ortholog); mitogen-activated protein kinase kinase binding (ortholog); mitogen-activated protein kinase kinase kinase binding (ortholog); INVOLVED IN JNK cascade (ortholog); negative regulation of JNK cascade (ortholog); negative regulation of MAPK cascade (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; ASSOCIATED WITH amenorrhea (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dual specificity protein phosphatase 19
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21385,736,631 - 85,763,434 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B85,751,609 - 85,778,412 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B70,347,712 - 70,371,852 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B188,157,061 - 188,178,277 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B188,157,061 - 188,178,266 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DUSP19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21385,736,631 - 85,763,434 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B85,751,609 - 85,778,412 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B70,347,712 - 70,371,852 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B188,157,061 - 188,178,277 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B188,157,061 - 188,178,266 (+)Ensemblpanpan1.1panPan2
DUSP19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382183,078,747 - 183,100,008 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2183,078,559 - 183,100,008 (+)EnsemblGRCh38hg38GRCh38
GRCh372183,943,475 - 183,964,736 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362183,651,732 - 183,672,981 (+)NCBINCBI36Build 36hg18NCBI36
Build 342183,768,992 - 183,790,226NCBI
Celera2177,539,400 - 177,560,844 (+)NCBICelera
Cytogenetic Map2q32.1NCBI
HuRef2175,802,186 - 175,823,524 (+)NCBIHuRef
CHM1_12183,949,183 - 183,970,629 (+)NCBICHM1_1
T2T-CHM13v2.02183,567,739 - 183,589,000 (+)NCBIT2T-CHM13v2.0
Dusp19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39280,447,558 - 80,462,005 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl280,447,389 - 80,462,705 (+)EnsemblGRCm39 Ensembl
GRCm38280,617,214 - 80,631,661 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl280,617,045 - 80,632,361 (+)EnsemblGRCm38mm10GRCm38
MGSCv37280,457,371 - 80,471,818 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36280,418,053 - 80,432,500 (+)NCBIMGSCv36mm8
Celera282,284,005 - 82,298,452 (+)NCBICelera
Cytogenetic Map2C3NCBI
cM Map248.31NCBI
Dusp19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8385,945,289 - 86,081,289 (+)NCBIGRCr8
mRatBN7.2365,538,424 - 65,554,465 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl365,538,420 - 65,553,534 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx368,890,852 - 68,903,336 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0377,474,410 - 77,486,894 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0375,234,840 - 75,250,812 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0367,849,966 - 67,862,475 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl367,849,966 - 67,862,475 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0374,406,311 - 74,418,820 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4363,473,333 - 63,485,843 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1363,369,862 - 63,382,210 (+)NCBI
Celera364,984,512 - 64,997,042 (+)NCBICelera
Cytogenetic Map3q24NCBI
Dusp19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540314,420,243 - 14,440,210 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540314,421,057 - 14,439,829 (-)NCBIChiLan1.0ChiLan1.0
DUSP19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13626,095,436 - 26,111,700 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3626,095,463 - 26,111,774 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3625,992,877 - 26,008,486 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03626,249,353 - 26,265,172 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3626,247,729 - 26,270,212 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13626,375,521 - 26,391,166 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03626,306,406 - 26,322,096 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03626,448,561 - 26,464,353 (+)NCBIUU_Cfam_GSD_1.0
Dusp19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303143,099,366 - 143,118,272 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650911,653,199 - 11,672,476 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650911,653,282 - 11,670,425 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DUSP19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1588,549,275 - 88,571,883 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11588,549,250 - 88,574,978 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21598,104,160 - 98,124,373 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DUSP19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11068,582,797 - 68,607,249 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1068,583,314 - 68,610,537 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040130,937,243 - 130,956,474 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dusp19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248444,798,455 - 4,818,818 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248444,798,542 - 4,822,739 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000035969   ⟹   ENSPPAP00000013299
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B188,157,061 - 188,178,266 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000035975   ⟹   ENSPPAP00000013305
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B188,157,061 - 188,174,170 (+)Ensembl
RefSeq Acc Id: XM_003823524   ⟹   XP_003823572
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21385,736,631 - 85,763,434 (+)NCBI
NHGRI_mPanPan12B85,751,609 - 85,778,412 (+)NCBI
Mhudiblu_PPA_v02B70,347,721 - 70,371,852 (+)NCBI
PanPan1.12B188,157,061 - 188,178,277 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008977180   ⟹   XP_008975428
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21385,736,631 - 85,763,434 (+)NCBI
NHGRI_mPanPan12B85,751,609 - 85,778,412 (+)NCBI
Mhudiblu_PPA_v02B70,347,718 - 70,371,852 (+)NCBI
PanPan1.12B188,157,061 - 188,174,177 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024928037   ⟹   XP_024783805
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21385,736,631 - 85,763,434 (+)NCBI
NHGRI_mPanPan12B85,751,609 - 85,778,412 (+)NCBI
Mhudiblu_PPA_v02B70,347,712 - 70,371,263 (+)NCBI
PanPan1.12B188,157,061 - 188,177,904 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003823572 (Get FASTA)   NCBI Sequence Viewer  
  XP_008975428 (Get FASTA)   NCBI Sequence Viewer  
  XP_024783805 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000013299.1
  ENSPPAP00000013305.1
Reference Protein Sequences
RefSeq Acc Id: XP_003823572   ⟸   XM_003823524
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A7Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008975428   ⟸   XM_008977180
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A8S5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024783805   ⟸   XM_024928037
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSPPAP00000013299   ⟸   ENSPPAT00000035969
RefSeq Acc Id: ENSPPAP00000013305   ⟸   ENSPPAT00000035975
Protein Domains
Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029833 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000035969.1 UniProtKB/TrEMBL
  ENSPPAT00000035975.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/TrEMBL
InterPro Dual-sp_phosphatase_cat-dom UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL_dom UniProtKB/TrEMBL
KEGG Report pps:100979178 UniProtKB/TrEMBL
NCBI Gene DUSP19 ENTREZGENE
PANTHER DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 UniProtKB/TrEMBL
  DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 UniProtKB/TrEMBL
Pfam DSPc UniProtKB/TrEMBL
PRINTS ADSPHPHTASE UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/TrEMBL
SMART DSPc UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/TrEMBL
UniProt A0A2R9A7Q3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A8S5 ENTREZGENE, UniProtKB/TrEMBL