SMYD3 (SET and MYND domain containing 3) - Rat Genome Database

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Gene: SMYD3 (SET and MYND domain containing 3) Pan paniscus
Analyze
Symbol: SMYD3
Name: SET and MYND domain containing 3
RGD ID: 11707460
Description: ENCODES a protein that exhibits histone H3K36 dimethyltransferase activity (inferred); histone H4 methyltransferase activity (inferred); metal ion binding (inferred); INVOLVED IN cellular response to dexamethasone stimulus (ortholog); establishment of protein localization (ortholog); myotube cell development (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH amenorrhea (ortholog); amphetamine abuse (ortholog); developmental and epileptic encephalopathy 54 (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone-lysine N-methyltransferase SMYD3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212,624,092 - 3,383,506 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112,841,208 - 3,607,222 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01221,371,348 - 222,125,774 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11226,737,739 - 227,481,309 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1226,737,960 - 227,481,191 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SMYD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212,624,092 - 3,383,506 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112,841,208 - 3,607,222 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01221,371,348 - 222,125,774 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11226,737,739 - 227,481,309 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1226,737,960 - 227,481,191 (-)Ensemblpanpan1.1panPan2
SMYD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381245,749,347 - 246,507,279 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1245,749,342 - 246,507,312 (-)EnsemblGRCh38hg38GRCh38
GRCh371245,912,649 - 246,670,581 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361243,979,267 - 244,647,334 (-)NCBINCBI36Build 36hg18NCBI36
Build 341242,238,685 - 242,906,752NCBI
Celera1219,204,089 - 219,959,418 (-)NCBICelera
Cytogenetic Map1q44NCBI
HuRef1216,300,241 - 217,057,123 (-)NCBIHuRef
CHM1_11247,184,928 - 247,943,100 (-)NCBICHM1_1
T2T-CHM13v2.01245,170,078 - 245,930,104 (-)NCBIT2T-CHM13v2.0
Smyd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,779,525 - 179,345,618 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,779,525 - 179,345,606 (-)EnsemblGRCm39 Ensembl
GRCm381178,951,960 - 179,518,053 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,951,960 - 179,518,041 (-)EnsemblGRCm38mm10GRCm38
MGSCv371180,885,162 - 181,448,134 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361180,791,706 - 181,354,678 (-)NCBIMGSCv36mm8
Celera1186,017,554 - 186,588,962 (-)NCBICelera
Cytogenetic Map1H4NCBI
cM Map183.48NCBI
Smyd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81393,241,274 - 93,798,221 (-)NCBIGRCr8
mRatBN7.21390,709,263 - 91,266,209 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1390,709,270 - 91,266,253 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1393,214,478 - 93,771,407 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01394,614,652 - 95,171,578 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01391,792,563 - 92,346,249 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01397,330,120 - 97,807,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013102,581,420 - 102,588,971 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.013102,350,012 - 102,473,942 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41394,643,716 - 95,108,789 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1390,265,163 - 90,818,620 (-)NCBICelera
Cytogenetic Map13q26NCBI
Smyd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554068,768,588 - 9,417,525 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554068,768,365 - 9,417,612 (-)NCBIChiLan1.0ChiLan1.0
SMYD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1736,561,080 - 37,250,336 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl736,565,901 - 37,250,578 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha736,041,500 - 36,732,806 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0736,391,898 - 37,082,573 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl736,396,600 - 37,082,534 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1736,231,858 - 36,922,858 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0736,245,479 - 36,930,875 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0736,513,397 - 37,199,813 (-)NCBIUU_Cfam_GSD_1.0
Smyd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934449,528,419 - 50,211,118 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365264,536,142 - 5,218,657 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365264,536,157 - 5,218,883 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMYD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1018,267,189 - 19,019,642 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11018,267,598 - 19,019,520 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21020,923,785 - 21,568,712 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103230910
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12582,794,748 - 83,531,942 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605585,053,359 - 85,234,932 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smyd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477113,149,649 - 13,943,137 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477113,149,547 - 13,943,352 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000051847   ⟹   ENSPPAP00000028999
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1226,737,960 - 227,481,191 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000051854   ⟹   ENSPPAP00000029006
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1227,308,011 - 227,481,191 (-)Ensembl
RefSeq Acc Id: XM_003807985   ⟹   XP_003808033
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212,624,092 - 3,383,506 (+)NCBI
NHGRI_mPanPan112,841,208 - 3,607,222 (+)NCBI
Mhudiblu_PPA_v01221,371,348 - 222,125,773 (-)NCBI
PanPan1.11226,737,741 - 227,481,309 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008960083   ⟹   XP_008958331
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212,624,095 - 3,383,506 (+)NCBI
NHGRI_mPanPan112,841,211 - 3,607,222 (+)NCBI
Mhudiblu_PPA_v01221,371,348 - 222,125,774 (-)NCBI
PanPan1.11226,737,739 - 227,481,305 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034950165   ⟹   XP_034806056
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212,624,563 - 3,383,506 (+)NCBI
NHGRI_mPanPan112,841,674 - 3,607,222 (+)NCBI
Mhudiblu_PPA_v01221,371,348 - 222,125,310 (-)NCBI
RefSeq Acc Id: XM_034950172   ⟹   XP_034806063
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212,624,842 - 3,383,506 (+)NCBI
NHGRI_mPanPan112,841,967 - 3,607,222 (+)NCBI
Mhudiblu_PPA_v01221,371,348 - 222,124,968 (-)NCBI
RefSeq Acc Id: XM_057298969   ⟹   XP_057154952
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212,624,564 - 3,383,506 (+)NCBI
NHGRI_mPanPan112,841,826 - 3,607,222 (+)NCBI
RefSeq Acc Id: XM_057298991   ⟹   XP_057154974
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212,963,298 - 3,383,506 (+)NCBI
NHGRI_mPanPan113,187,789 - 3,607,222 (+)NCBI
RefSeq Acc Id: XM_057298996   ⟹   XP_057154979
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212,985,368 - 3,383,506 (+)NCBI
NHGRI_mPanPan113,209,865 - 3,607,222 (+)NCBI
RefSeq Acc Id: XM_063608732   ⟹   XP_063464802
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213,038,281 - 3,383,506 (+)NCBI
RefSeq Acc Id: XP_008958331   ⟸   XM_008960083
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_003808033   ⟸   XM_003807985
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BH65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034806056   ⟸   XM_034950165
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034806063   ⟸   XM_034950172
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000029006   ⟸   ENSPPAT00000051854
RefSeq Acc Id: ENSPPAP00000028999   ⟸   ENSPPAT00000051847
RefSeq Acc Id: XP_057154952   ⟸   XM_057298969
- Peptide Label: isoform X2
RefSeq Acc Id: XP_057154974   ⟸   XM_057298991
- Peptide Label: isoform X4
RefSeq Acc Id: XP_057154979   ⟸   XM_057298996
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063464802   ⟸   XM_063608732
- Peptide Label: isoform X4
Protein Domains
MYND-type   SET


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037519 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000051847.1 UniProtKB/TrEMBL
  ENSPPAT00000051854.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.220.160 UniProtKB/TrEMBL
  1.25.40.10 UniProtKB/TrEMBL
  1.25.40.970 UniProtKB/TrEMBL
  2.170.270.10 UniProtKB/TrEMBL
  6.10.140.2220 UniProtKB/TrEMBL
InterPro Hist-Lys_N-MeTrfase_Smyd3 UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
  SMYD3_SET UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  Znf_MYND UniProtKB/TrEMBL
KEGG Report pps:100990317 UniProtKB/TrEMBL
NCBI Gene SMYD3 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE SMYD UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3 UniProtKB/TrEMBL
Pfam SET UniProtKB/TrEMBL
  zf-MYND UniProtKB/TrEMBL
PROSITE SAM_MT43_2 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
  ZF_MYND_1 UniProtKB/TrEMBL
  ZF_MYND_2 UniProtKB/TrEMBL
SMART SET UniProtKB/TrEMBL
Superfamily-SCOP SSF82199 UniProtKB/TrEMBL
UniProt A0A2R9BH65 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BQW6_PANPA UniProtKB/TrEMBL