The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
cucurbitacin B results in increased expression of BAK1 mRNA; cucurbitacin B results in increased expression of BAK1 protein [cucurbitacin B co-treated with Gefitinib] results in increased expression of BAK1 mRNA; [cucurbitacin B co-treated with Gefitinib] results in increased expression of BAK1 protein
cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of BAX mRNA] [cucurbitacin B co-treated with Gefitinib] results in increased expression of BAX mRNA; [cucurbitacin B co-treated with Gefitinib] results in increased expression of BAX protein cucurbitacin B results in increased expression of BAX mRNA; cucurbitacin B results in increased expression of BAX protein
cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of BCL2 mRNA] cucurbitacin B results in decreased expression of BCL2 mRNA; cucurbitacin B results in decreased expression of BCL2 protein [cucurbitacin B co-treated with Gefitinib] results in decreased expression of BCL2 mRNA; [cucurbitacin B co-treated with Gefitinib] results in decreased expression of BCL2 protein
cucurbitacin B results in decreased expression of BCL2L1 mRNA [cucurbitacin B co-treated with Gefitinib] results in decreased expression of BCL2L1 mRNA
[cucurbitacin B co-treated with Gefitinib] results in increased expression of BCL2L11 mRNA cucurbitacin B results in increased expression of BCL2L11 mRNA
cucurbitacin B results in increased cleavage of CASP3 protein [cucurbitacin B co-treated with Gefitinib] results in increased cleavage of CASP3 protein
cucurbitacin B results in decreased expression of CCND1 cucurbitacin B results in decreased expression of CCND1 mRNA; cucurbitacin B results in decreased expression of CCND1 protein [cucurbitacin B co-treated with Gefitinib] results in decreased expression of CCND1 mRNA; [cucurbitacin B co-treated with Gefitinib] results in decreased expression of CCND1 protein
cucurbitacin B results in increased expression of CDKN1B protein [cucurbitacin B co-treated with Gefitinib] results in increased expression of CDKN1B protein
cucurbitacin B results in decreased expression of CEBPA mRNA STAT3 protein affects the reaction [cucurbitacin B results in decreased expression of CEBPA mRNA]
cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of GOT1 protein] cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of GOT1 protein]
cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of GPT protein] cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of GPT protein]
cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of HIF1A mRNA]; cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of HIF1A protein] cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of HIF1A mRNA]; cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of HIF1A protein]
cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased secretion of IL1B protein]; cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein] cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of IL1B mRNA]
cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of IL6 mRNA]; cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of IL6 protein] cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of IL6 mRNA]; cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of IL6 protein]; cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased secretion of IL6 protein]
[WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin B; cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of STAT3 mRNA]; cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of STAT3 protein]; cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]; cucurbitacin B results in decreased phosphorylation of and results in decreased activity of STAT3 protein; STAT3 protein affects the reaction [cucurbitacin B results in decreased expression of CEBPA mRNA]; STAT3 protein affects the reaction [cucurbitacin B results in decreased expression of PPARG mRNA] STAT3 protein affects the susceptibility to cucurbitacin B [cucurbitacin B co-treated with Gefitinib] results in decreased phosphorylation of STAT3 protein; cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of and results in increased phosphorylation of STAT3 mRNA] cucurbitacin B results in decreased phosphorylation of STAT3 protein
cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of TNF mRNA]; cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of TNF protein]; cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased secretion of TNF protein]; cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of TNF mRNA]; cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of TNF protein]
[Ketoconazole results in increased activity of CYP51 protein] which results in increased abundance of Lanosterol CYP51A1 gene inhibits the reaction [Fluconazole results in decreased metabolism of and results in increased abundance of Lanosterol]; CYP51A1 gene inhibits the reaction [Itraconazole results in decreased metabolism of and results in increased abundance of Lanosterol]; CYP51A1 gene inhibits the reaction [Ketoconazole results in decreased metabolism of and results in increased abundance of Lanosterol]; CYP51A1 gene inhibits the reaction [Voriconazole results in decreased metabolism of and results in increased abundance of Lanosterol]