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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ganoderol B
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Accession:CHEBI:142261 term browser browse the term
Definition:A tetracyclic triterpenoid that is lanosta-7,9(11),24-triene which is substituted by hydroxy groups at positions 3 and 27. It has been isolated from several Ganoderma species.
Synonyms:exact_synonym: (3beta,24E)-lanosta-7,9(11),24-triene-3,26-diol
 related_synonym: Formula=C30H48O2;   InChI=1S/C30H48O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25-26,31-32H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22-,25+,26+,28-,29-,30+/m1/s1;   InChIKey=AOXXVRDKZLRGTJ-AZIDVCJLSA-N;   SMILES=C1([C@]2([C@](CC[C@@H]1O)(C=3C(=CC2)[C@]4([C@@](CC3)(C)[C@](CC4)([C@@H](CC/C=C(/CO)\\C)C)[H])C)C)[H])(C)C;   ganodermadiol
 xref: CAS:104700-96-1;   FooDB:FDB013983;   HMDB:HMDB0035314;   KNApSAcK:C00023868
 xref_mesh: MESH:C521787
 xref: PMID:11908995;   PMID:12628419;   PMID:17313101;   PMID:17499997;   PMID:21596546;   PMID:23790868;   PMID:28875673;   PMID:28912878;   PMID:29748985


show annotations for term's descendants           Sort by:
ganoderol B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO ganoderol B binds to and results in decreased activity of AR protein; ganoderol B inhibits the reaction [Dihydrotestosterone binds to AR protein] CTD PMID:17499997 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression ISO ganoderol B results in decreased expression of KLK3 mRNA CTD PMID:17499997 NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases activity EXP ganoderol B results in decreased activity of SRD5A1 protein CTD PMID:17499997 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20845
    role 20805
      biological role 20803
        antimicrobial agent 18553
          antiviral agent 11445
            ganoderol B 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 20845
    subatomic particle 20843
      composite particle 20843
        hadron 20843
          baryon 20843
            nucleon 20843
              atomic nucleus 20843
                atom 20843
                  main group element atom 20766
                    p-block element atom 20766
                      carbon group element atom 20699
                        carbon atom 20693
                          organic molecular entity 20693
                            organic molecule 20637
                              organic cyclic compound 20387
                                organic polycyclic compound 17540
                                  steroid 15292
                                    hydroxy steroid 15113
                                      3-hydroxy steroid 13783
                                        sterol 480
                                          3beta-sterol 474
                                            ganoderol B 3
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