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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ganoderol B
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Accession:CHEBI:142261 term browser browse the term
Definition:A tetracyclic triterpenoid that is lanosta-7,9(11),24-triene which is substituted by hydroxy groups at positions 3 and 27. It has been isolated from several Ganoderma species.
Synonyms:exact_synonym: (3beta,24E)-lanosta-7,9(11),24-triene-3,26-diol
 related_synonym: Formula=C30H48O2;   InChI=1S/C30H48O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25-26,31-32H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22-,25+,26+,28-,29-,30+/m1/s1;   InChIKey=AOXXVRDKZLRGTJ-AZIDVCJLSA-N;   SMILES=C1([C@]2([C@](CC[C@@H]1O)(C=3C(=CC2)[C@]4([C@@](CC3)(C)[C@](CC4)([C@@H](CC/C=C(/CO)\\C)C)[H])C)C)[H])(C)C;   ganodermadiol
 xref: CAS:104700-96-1;   FooDB:FDB013983;   HMDB:HMDB0035314;   KNApSAcK:C00023868
 xref_mesh: MESH:C521787
 xref: PMID:11908995;   PMID:12628419;   PMID:17313101;   PMID:17499997;   PMID:21596546;   PMID:23790868;   PMID:28875673;   PMID:28912878;   PMID:29748985


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ganoderol B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO ganoderol B binds to and results in decreased activity of AR protein; ganoderol B inhibits the reaction [Dihydrotestosterone binds to AR protein] CTD PMID:17499997 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
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G Srd5a1 steroid 5 alpha-reductase 1 decreases activity EXP ganoderol B results in decreased activity of SRD5A1 protein CTD PMID:17499997 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        antimicrobial agent 17329
          antiviral agent 10253
            ganoderol B 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic polycyclic compound 16393
                                  steroid 12793
                                    hydroxy steroid 12375
                                      3-hydroxy steroid 10004
                                        sterol 417
                                          3beta-sterol 411
                                            ganoderol B 2
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