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ONTOLOGY REPORT - ANNOTATIONS


Term:lanosterol
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Accession:CHEBI:16521 term browser browse the term
Definition:A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived.
Synonyms:related_synonym: (3beta)-lanosta-8,24-dien-3-ol;   (3beta,5alpha)-4,4,14-trimethylcholesta-8,24-dien-3-ol;   4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol;   Formula=C30H50O;   InChI=1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1;   InChIKey=CAHGCLMLTWQZNJ-BQNIITSRSA-N;   Lanosta-8,24-dien-3beta-ol;   Lanosterin;   SMILES=C[C@H](CCC=C(C)C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3
 alt_id: CHEBI:14500;   CHEBI:25011;   CHEBI:43584;   CHEBI:6374
 xref: Beilstein:2226449;   CAS:79-63-0;   DrugBank:DB03696;   HMDB:HMDB0001251;   KEGG:C01724;   KNApSAcK:C00003657;   LIPID_MAPS_instance:LMST01010017
 xref_mesh: MESH:D007810
 xref: MetaCyc:LANOSTEROL;   PDBeChem:LAN;   PMID:14660793;   PMID:16445886;   PMID:21818119;   PMID:21838962;   PMID:22824432;   PMID:22933236;   PMID:22988818;   PMID:24525128;   PMID:26069216;   PMID:26200341;   Reaxys:2226449;   Wikipedia:Lanosterol


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lanosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:6480464
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:6480464
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:6480464
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:6480464
G Marchf6 membrane associated ring-CH-type finger 6 JBrowse link 2 84,533,546 84,608,743 RGD:6480464
14-demethyllanosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Msmo1 methylsterol monooxygenase 1 JBrowse link 16 26,859,441 26,875,880 RGD:6480464
24,25-dihydrolanosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      biological role 19704
        biochemical role 19206
          metabolite 19180
            eukaryotic metabolite 18807
              plant metabolite 17281
                lanosterol 7
                  14-demethyllanosterol + 1
                  24,25-dihydrolanosterol + 2
                  lanosteryl ester + 0
                  pneumocysterol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic molecule 19441
                              organic cyclic compound 19203
                                organic polycyclic compound 16046
                                  steroid 12803
                                    hydroxy steroid 12382
                                      3-hydroxy steroid 10008
                                        sterol 412
                                          3beta-sterol 406
                                            lanosterol 7
                                              14-demethyllanosterol + 1
                                              24,25-dihydrolanosterol + 2
                                              lanosteryl ester + 0
                                              pneumocysterol 0
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