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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lanost-8-ene-3beta,30-diol
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Accession:CHEBI:87057 term browser browse the term
Definition:A tetracyclic triterpenoid that is lanost-8-ene carrying two hydroxy substituents at positions 3beta and 30.
Synonyms:exact_synonym: (3beta)-lanost-8-ene-3,30-diol
 related_synonym: 32-Hydroxy-24,25-dihydrolanosterol;   4,4-Dimethyl-14alpha-hydroxymethyl-5alpha-cholesta-8-en-3beta-ol;   4,4-dimethyl-14alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol;   Formula=C30H52O2;   InChI=1S/C30H52O2/c1-20(2)9-8-10-21(3)22-14-18-30(19-31)24-11-12-25-27(4,5)26(32)15-16-28(25,6)23(24)13-17-29(22,30)7/h20-22,25-26,31-32H,8-19H2,1-7H3/t21-,22-,25+,26+,28-,29-,30-/m1/s1;   InChIKey=SJPDNXKPBQHPMZ-PUXRVUTHSA-N;   SMILES=CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(CO)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3;   lanost-8-en-3beta,30-diol
 xref: CAS:59200-39-4;   HMDB:HMDB0012160;   LIPID_MAPS_instance:LMST01010224
 xref_mesh: MESH:C050483
 xref: MetaCyc:CPD-8607;   Reaxys:4821112


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lanost-8-ene-3beta,30-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases activity ISO 32-hydroxy-24,25-dihydrolanosterol results in decreased activity of HMGCR protein CTD PMID:12617470 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      molecular entity 19784
        polyatomic entity 19697
          molecule 19520
            cyclic compound 19324
              polycyclic compound 18525
                organic polycyclic compound 16384
                  tetracyclic triterpenoid 244
                    lanost-8-ene-3beta,30-diol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                organic polycyclic compound 16384
                                  steroid 12788
                                    hydroxy steroid 12371
                                      3-hydroxy steroid 9999
                                        sterol 417
                                          3beta-sterol 411
                                            lanost-8-ene-3beta,30-diol 1
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