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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10529
Species: Mus musculus
RGD Object: Gene
Symbol: Ephx1
Name: epoxide hydrolase 1, microsomal
Acc ID: CHEBI:16521
Term: lanosterol
Definition: A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived.
Chemical ID: MESH:D007810
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ephx1multiple interactionsEXP 6480464CTDLanosterol analog inhibits the reaction [EPHX1 protein results in increased metabolism of cholesterol alpha-oxide]PMID:2043152
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