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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased CD4-positive, alpha-beta memory T cell number
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Accession:MP:0010835 term browser browse the term
Definition:increased number of CD4-positive, alpha-beta long-lived T cells with the phenotype CD45RO-positive and CD127-positive, or also described as being CD25-negative, CD44-high, and CD122- high
Synonyms:exact_synonym: increased CD4-positive, alpha-beta memory T-lymphocyte number
 related_synonym: increased T4.Mem.Sp number
 xref: CL:0000897


show annotations for term's descendants           Sort by:
increased CD4-positive, alpha-beta memory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef1 Rho guanine nucleotide exchange factor 1 IEA MGI NCBI chr 7:24,601,762...24,626,019
Ensembl chr 7:24,602,337...24,626,019 		JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B IEA MGI NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IEA MGI NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Dock2 dedicator of cyto-kinesis 2 IAGP MGI PMID:27210752 NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719 		JBrowse link
G Dph6 diphthamine biosynthesis 6 IEA MGI NCBI chr 2:114,346,897...114,485,518
Ensembl chr 2:114,346,897...114,485,445 		JBrowse link
G Hbs1l Hbs1-like (S. cerevisiae) IEA MGI NCBI chr10:21,171,876...21,244,788
Ensembl chr10:21,171,878...21,244,797 		JBrowse link
G Id3 inhibitor of DNA binding 3 IAGP MGI PMID:20932862 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066 		JBrowse link
G Lair1 leukocyte-associated Ig-like receptor 1 IAGP MGI PMID:22156345 NCBI chr 7:4,010,072...4,076,566
Ensembl chr 7:4,006,401...4,066,178 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IAGP MGI PMID:28471497 NCBI chr 1:152,675,904...152,712,743
Ensembl chr 1:152,675,945...152,712,742 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) IAGP MGI PMID:23619366 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IAGP MGI PMID:22719950 NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G Siae sialic acid acetylesterase IAGP MGI PMID:27210752 NCBI chr 9:37,525,117...37,559,554
Ensembl chr 9:37,466,994...37,560,951 		JBrowse link
G Syk spleen tyrosine kinase IAGP MGI PMID:22728826 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828 		JBrowse link
G Tnf tumor necrosis factor IAGP MGI PMID:18854186 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator IAGP MGI PMID:21683627 NCBI chr19:3,985,222...3,999,340
Ensembl chr19:3,985,186...3,999,340 		JBrowse link
increased central memory CD4-positive, alpha-beta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ataxia telangiectasia mutated IEA MGI NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 IEA MGI NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695 		JBrowse link
G Ctsl cathepsin L IEA MGI NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704 		JBrowse link
G Dclre1c DNA cross-link repair 1C IEA MGI NCBI chr 2:3,425,112...3,475,248
Ensembl chr 2:3,425,168...3,465,167 		JBrowse link
G Diaph1 diaphanous related formin 1 IEA MGI NCBI chr18:37,976,654...38,068,573
Ensembl chr18:37,976,654...38,068,529 		JBrowse link
G Dock2 dedicator of cyto-kinesis 2 IEA MGI NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719 		JBrowse link
G Dock8 dedicator of cytokinesis 8 IEA MGI NCBI chr19:24,976,753...25,179,796
Ensembl chr19:24,976,898...25,179,796 		JBrowse link
G Fas Fas cell surface death receptor IEA MGI NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IEA MGI NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Itk IL2 inducible T cell kinase IEA MGI NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342 		JBrowse link
G Lmbr1l limb region 1 like IEA MGI NCBI chr15:98,801,798...98,815,944
Ensembl chr15:98,801,798...98,816,112 		JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha IEA MGI NCBI chr16:17,098,215...17,224,178
Ensembl chr16:17,098,215...17,224,178 		JBrowse link
G Pnp purine-nucleoside phosphorylase IEA MGI NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869 		JBrowse link
G Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform IEA MGI NCBI chr14:20,549,432...20,596,641
Ensembl chr14:20,549,432...20,596,641 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IEA MGI NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rac2 Rac family small GTPase 2 IEA MGI NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IEA MGI NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G Stk4 serine/threonine kinase 4 IEA MGI NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444 		JBrowse link
G Tg thyroglobulin IEA MGI NCBI chr15:66,542,606...66,722,570
Ensembl chr15:66,542,602...66,722,570 		JBrowse link
G Themis thymocyte selection associated IEA MGI NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 IEA MGI NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888 		JBrowse link
G Vav1 vav 1 oncogene IEA MGI NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IEA MGI NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
increased effector memory CD4-positive, alpha-beta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ataxia telangiectasia mutated IEA MGI NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Casp8 caspase 8 IEA MGI NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IEA MGI NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Ctsl cathepsin L IEA MGI NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704 		JBrowse link
G Dck deoxycytidine kinase IAGP MGI PMID:22407915 NCBI chr 5:88,912,872...88,931,136
Ensembl chr 5:88,912,855...88,931,140 		JBrowse link
G Dclre1c DNA cross-link repair 1C IEA MGI NCBI chr 2:3,425,112...3,475,248
Ensembl chr 2:3,425,168...3,465,167 		JBrowse link
G Diaph1 diaphanous related formin 1 IEA MGI NCBI chr18:37,976,654...38,068,573
Ensembl chr18:37,976,654...38,068,529 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IEA MGI NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Dock2 dedicator of cyto-kinesis 2 IEA MGI NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719 		JBrowse link
G Dock8 dedicator of cytokinesis 8 IEA MGI NCBI chr19:24,976,753...25,179,796
Ensembl chr19:24,976,898...25,179,796 		JBrowse link
G Fas Fas cell surface death receptor IEA MGI NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fbxo7 F-box protein 7 IAGP MGI PMID:30840666 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IEA MGI NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Il2rb interleukin 2 receptor, beta chain IEA MGI NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IEA MGI NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229 		JBrowse link
G Itgb2 integrin beta 2 IEA MGI NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Itk IL2 inducible T cell kinase IEA MGI NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342 		JBrowse link
G Jak3 Janus kinase 3 IEA MGI NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Lepr leptin receptor IEA MGI NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent IEA MGI NCBI chr 8:10,020,020...10,027,680
Ensembl chr 8:10,019,049...10,027,686 		JBrowse link
G Lmbr1l limb region 1 like IAGP MGI PMID:31073040 NCBI chr15:98,801,798...98,815,944
Ensembl chr15:98,801,798...98,816,112 		JBrowse link
G Nckap1l NCK associated protein 1 like IEA MGI NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237 		JBrowse link
G Pnp purine-nucleoside phosphorylase IEA MGI NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IEA MGI NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) IAGP MGI PMID:23619366 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IEA MGI NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rac2 Rac family small GTPase 2 IEA MGI NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IAGP MGI PMID:24336796 NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G Rel reticuloendotheliosis oncogene IEA MGI NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970 		JBrowse link
G Rorc RAR-related orphan receptor gamma IEA MGI NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) IAGP MGI PMID:24551030 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IEA MGI NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stk4 serine/threonine kinase 4 IEA MGI NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444 		JBrowse link
G Tcf12 transcription factor 12 IEA MGI NCBI chr 9:71,751,534...72,019,611
Ensembl chr 9:71,749,970...72,019,153 		JBrowse link
G Themis thymocyte selection associated IEA MGI NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
G Tlr7 toll-like receptor 7 IAGP MGI PMID:35477763 NCBI chr  X:166,086,376...166,113,570
Ensembl chr  X:166,087,925...166,113,554 		JBrowse link
G Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 IEA MGI NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559 		JBrowse link
G Vav1 vav 1 oncogene IEA MGI NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031 		JBrowse link
G Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 IEA MGI NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IEA MGI NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
G Zc3h12c zinc finger CCCH type containing 12C IAGP MGI PMID:31126966 NCBI chr 9:52,020,869...52,080,028
Ensembl chr 9:52,022,644...52,079,872 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16975
    immune system phenotype 5728
      abnormal immune system morphology 4099
        abnormal immune system cell morphology 2844
          abnormal leukocyte morphology 2823
            abnormal leukocyte cell number 2534
              increased leukocyte cell number 1755
                increased lymphocyte cell number 1000
                  increased T cell number 647
                    increased memory T cell number 146
                      increased CD4-positive, alpha-beta memory T cell number 61
                        increased central memory CD4-positive, alpha-beta T cell number 24
                        increased effector memory CD4-positive, alpha-beta T cell number 42
Path 2
Term Annotations click to browse term
  mammalian phenotype 16975
    immune system phenotype 5728
      abnormal immune system morphology 4099
        abnormal immune system cell morphology 2844
          abnormal leukocyte morphology 2823
            abnormal mononuclear cell morphology 2278
              abnormal lymphocyte morphology 1844
                abnormal T cell morphology 1175
                  abnormal effector T cell morphology 858
                    abnormal CD4-positive, alpha beta T cell morphology 607
                      abnormal CD4-positive, alpha-beta T cell number 520
                        increased CD4-positive, alpha-beta T cell number 287
                          increased CD4-positive, alpha-beta memory T cell number 61
                            increased central memory CD4-positive, alpha-beta T cell number 24
                            increased effector memory CD4-positive, alpha-beta T cell number 42
paths to the root