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Gene: Dicer1 (dicer 1, ribonuclease type III) Mus musculus
Symbol: Dicer1
Name: dicer 1, ribonuclease type III
Description: Exhibits miRNA binding activity and ribonuclease III activity. Predicted to contribute to pre-miRNA binding activity. Involved in several processes, including animal organ development; nervous system development; and regulation of RNA metabolic process. Localizes to RISC complex and cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study DiGeorge syndrome and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in multinodular goiter and pleuropulmonary blastoma. Orthologous to human DICER1 (dicer 1, ribonuclease III); PARTICIPATES IN microRNA pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 7,12-dimethyltetraphene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110006F08Rik; D12Ertd7e; Dicer1, Dcr-1 homolog; double-strand-specific ribonuclease mDCR-1; endoribonuclease Dicer; mKIAA0928
Homo sapiens (human) : DICER1 (dicer 1, ribonuclease III)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dicer1 (dicer 1 ribonuclease III)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dicer1 (dicer 1, ribonuclease III)
Pan paniscus (bonobo/pygmy chimpanzee) : DICER1 (dicer 1, ribonuclease III)
Canis lupus familiaris (dog) : DICER1 (dicer 1, ribonuclease III)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dicer1 (dicer 1, ribonuclease III)
Sus scrofa (pig) : DICER1 (dicer 1, ribonuclease III)
Chlorocebus sabaeus (African green monkey) : DICER1 (dicer 1, ribonuclease III)
Heterocephalus glaber (naked mole-rat) : Dicer1 (dicer 1, ribonuclease III)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl12104,687,742 - 104,751,952 (-)EnsemblGRCm38mm10GRCm38
GRCm3812104,687,740 - 104,751,968 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712105,925,952 - 105,990,162 (-)NCBIGRCm37mm9NCBIm37
MGSCv3612105,092,486 - 105,153,002 (-)NCBImm8
Celera12105,918,245 - 105,982,441 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1254.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Dicer1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319700
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.