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Gene: Dicer1 (dicer 1, ribonuclease type III) Mus musculus
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Symbol: Dicer1
Name: dicer 1, ribonuclease type III
Description: Exhibits miRNA binding activity and ribonuclease III activity. Predicted to contribute to pre-miRNA binding activity. Involved in several processes, including animal organ development; nervous system development; and regulation of RNA metabolic process. Localizes to RISC complex and cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study DiGeorge syndrome and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in multinodular goiter and pleuropulmonary blastoma. Orthologous to human DICER1 (dicer 1, ribonuclease III); PARTICIPATES IN microRNA pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 7,12-dimethyltetraphene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110006F08Rik; D12Ertd7e; Dicer1, Dcr-1 homolog; double-strand-specific ribonuclease mDCR-1; endoribonuclease Dicer; mKIAA0928
Orthologs:
Homo sapiens (human) : DICER1 (dicer 1, ribonuclease III)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dicer1 (dicer 1 ribonuclease III)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dicer1 (dicer 1, ribonuclease III)
Pan paniscus (bonobo/pygmy chimpanzee) : DICER1 (dicer 1, ribonuclease III)
Canis lupus familiaris (dog) : DICER1 (dicer 1, ribonuclease III)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dicer1 (dicer 1, ribonuclease III)
Sus scrofa (pig) : DICER1 (dicer 1, ribonuclease III)
Chlorocebus sabaeus (African green monkey) : DICER1 (dicer 1, ribonuclease III)
Heterocephalus glaber (naked mole-rat) : Dicer1 (dicer 1, ribonuclease III)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl12104,687,742 - 104,751,952 (-)EnsemblGRCm38mm10GRCm38
GRCm3812104,687,740 - 104,751,968 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712105,925,952 - 105,990,162 (-)NCBIGRCm37mm9NCBIm37
MGSCv3612105,092,486 - 105,153,002 (-)NCBImm8
Celera12105,918,245 - 105,982,441 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1254.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Dicer1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319700
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.