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Gene: Unc93b1 (unc-93 homolog B1, TLR signaling regulator) Mus musculus
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Symbol: Unc93b1
Name: unc-93 homolog B1, TLR signaling regulator
Description: Exhibits Toll-like receptor binding activity. Involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; positive regulation of cytokine secretion; and toll-like receptor signaling pathway. Localizes to the cytoplasmic vesicle; endoplasmic reticulum; and lysosome. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human UNC93B1 (unc-93 homolog B1, TLR signaling regulator); PARTICIPATES IN Toll-like receptor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: protein unc-93 homolog B1; unc-93 homolog B; unc-93 homolog B1; unc-93 homolog B1 (C. elegans); Unc-93B1; Unc93b
Orthologs:
Homo sapiens (human) : UNC93B1 (unc-93 homolog B1, TLR signaling regulator)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Unc93b1 (unc-93 homolog B1, TLR signaling regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Unc93b1 (unc-93 homolog B1, TLR signaling regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : UNC93B1 (unc-93 homolog B1, TLR signaling regulator)
Canis lupus familiaris (dog) : UNC93B1 (unc-93 homolog B1, TLR signaling regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Unc93b1 (unc-93 homolog B1, TLR signaling regulator)
Sus scrofa (pig) : UNC93B1 (unc-93 homolog B1, TLR signaling regulator)
Chlorocebus sabaeus (African green monkey) : UNC93B1 (unc-93 homolog B1, TLR signaling regulator)
Heterocephalus glaber (naked mole-rat) : Unc93b1 (unc-93 homolog B1, TLR signaling regulator)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl193,935,186 - 3,949,340 (+)Ensembl
GRCm38193,935,158 - 3,949,340 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37193,935,186 - 3,949,340 (+)NCBIGRCm37mm9NCBIm37
MGSCv36193,935,219 - 3,949,340 (+)NCBImm8
Celera193,816,022 - 3,830,362 (+)NCBICelera
Cytogenetic Map19ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Unc93b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615140
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-02-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.