Arhgef1 (Rho guanine nucleotide exchange factor 1) - Rat Genome Database

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Gene: Arhgef1 (Rho guanine nucleotide exchange factor 1) Mus musculus
Analyze
Symbol: Arhgef1
Name: Rho guanine nucleotide exchange factor 1
RGD ID: 732383
MGI Page MGI
Description: Predicted to enable G protein-coupled receptor binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and microtubule depolymerization. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including genitourinary system; liver; lung; spleen; and telencephalon. Human ortholog(s) of this gene implicated in immunodeficiency 62. Orthologous to human ARHGEF1 (Rho guanine nucleotide exchange factor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: L; Lbc; lbc's second cousin; Lbcl2; Lsc; lymphoid blast crisis like 2; lymphoid blast crisis-like 2; Rho guanine nucleotide exchange factor (GEF) 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,601,762 - 24,626,019 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl724,602,337 - 24,626,019 (+)EnsemblGRCm39 Ensembl
GRCm38724,902,986 - 24,926,594 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl724,902,912 - 24,926,594 (+)EnsemblGRCm38mm10GRCm38
MGSCv37725,688,005 - 25,711,611 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36724,611,816 - 24,635,352 (+)NCBIMGSCv36mm8
Celera719,518,885 - 19,542,623 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
cytosol  (ISO)
membrane  (IEA)
plasma membrane  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aorta wall morphology  (IAGP)
abnormal B cell migration  (IAGP)
abnormal humoral immune response  (IAGP)
abnormal lymphocyte cell number  (IAGP)
abnormal lymphocyte physiology  (IAGP)
abnormal marginal zone B cell physiology  (IAGP)
abnormal neutrophil physiology  (IAGP)
abnormal systemic arterial blood pressure  (IAGP)
cardiac hypertrophy  (IAGP)
decreased B cell number  (IAGP)
decreased B cell proliferation  (IAGP)
decreased B-1 B cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IEA)
decreased dendritic cell number  (IEA)
decreased follicular B cell number  (IAGP)
decreased IgG level  (IAGP)
decreased IgM level  (IAGP)
decreased immature NK cell number  (IEA)
decreased Ly6C-positive immature NK cell number  (IEA)
decreased marginal zone B cell number  (IAGP)
decreased memory-marker CD4-positive NK T cell number  (IEA)
decreased memory-marker gamma-delta T cell number  (IEA)
decreased physiological sensitivity to xenobiotic  (IAGP)
decreased vasoconstriction  (IAGP)
enlarged spleen  (IAGP)
extramedullary hematopoiesis  (IAGP)
increased CD4-positive, alpha-beta memory T cell number  (IEA)
increased CD4-positive, alpha-beta T cell number  (IEA)
increased CD8-positive, alpha-beta memory T cell number  (IEA)
increased effector memory CD8-positive, alpha-beta T cell number  (IEA)
increased erythrocyte cell number  (IEA)
increased gamma-delta T cell number  (IEA)
increased germinal center B cell number  (IAGP)
increased hematocrit  (IEA)
increased hemoglobin content  (IEA)
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number  (IEA)
increased KLRG1-positive NK cell number  (IEA)
increased leukocyte cell number  (IAGP)
increased Ly6C low monocyte number  (IEA)
increased Ly6C-positive NK T cell number  (IEA)
increased mature NK cell number  (IEA)
increased monocyte cell number  (IEA)
increased plasmacytoid dendritic cell number  (IEA)
increased T cell proliferation  (IAGP)
preweaning lethality, incomplete penetrance  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8702517   PMID:8910315   PMID:9135076   PMID:9798653   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11526402   PMID:11544199   PMID:12477932   PMID:12520002  
PMID:12756248   PMID:12773540   PMID:12904583   PMID:14610273   PMID:15102471   PMID:15449545   PMID:15489334   PMID:15582152   PMID:15761153   PMID:15782199   PMID:15884057   PMID:16141072  
PMID:16141073   PMID:16263795   PMID:16286020   PMID:16602821   PMID:17000758   PMID:17463415   PMID:18025197   PMID:18157933   PMID:18322196   PMID:18799693   PMID:18940608   PMID:19570830  
PMID:20093499   PMID:20098430   PMID:20600037   PMID:21473788   PMID:21642988   PMID:21677750   PMID:21873635   PMID:22086927   PMID:22500016   PMID:22922362   PMID:25274307   PMID:27489999  
PMID:27923664   PMID:28378742   PMID:29095442   PMID:29130930   PMID:30457570   PMID:30973865   PMID:30994039   PMID:31219639   PMID:32245826   PMID:32560809   PMID:34321999   PMID:35143305  
PMID:37142655   PMID:38049580   PMID:38355793  


Genomics

Comparative Map Data
Arhgef1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,601,762 - 24,626,019 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl724,602,337 - 24,626,019 (+)EnsemblGRCm39 Ensembl
GRCm38724,902,986 - 24,926,594 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl724,902,912 - 24,926,594 (+)EnsemblGRCm38mm10GRCm38
MGSCv37725,688,005 - 25,711,611 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36724,611,816 - 24,635,352 (+)NCBIMGSCv36mm8
Celera719,518,885 - 19,542,623 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.52NCBI
ARHGEF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381941,883,184 - 41,930,141 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1941,883,173 - 41,930,150 (+)EnsemblGRCh38hg38GRCh38
GRCh371942,387,251 - 42,434,293 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,079,107 - 47,103,444 (+)NCBINCBI36Build 36hg18NCBI36
Build 341947,080,285 - 47,103,443NCBI
Celera1939,186,950 - 39,211,282 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1938,818,551 - 38,842,545 (+)NCBIHuRef
CHM1_11942,388,735 - 42,412,987 (+)NCBICHM1_1
T2T-CHM13v2.01944,702,671 - 44,749,424 (+)NCBIT2T-CHM13v2.0
Arhgef1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,626,884 - 89,648,823 (+)NCBIGRCr8
mRatBN7.2180,499,026 - 80,520,954 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,499,131 - 80,520,953 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx185,891,659 - 85,913,491 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,442,476 - 94,464,309 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0187,647,420 - 87,669,252 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0181,769,212 - 81,797,237 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,779,380 - 81,797,236 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,025,520 - 83,053,989 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,209,459 - 80,226,353 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1180,287,569 - 80,304,463 (+)NCBI
Celera174,946,561 - 74,968,150 (+)NCBICelera
Cytogenetic Map1q21NCBI
Arhgef1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955555941,539 - 961,407 (-)NCBIChiLan1.0ChiLan1.0
ARHGEF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22047,988,151 - 48,013,022 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11949,857,135 - 49,882,019 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01938,771,343 - 38,796,174 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11947,276,407 - 47,299,663 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1947,277,420 - 47,299,663 (+)Ensemblpanpan1.1panPan2
ARHGEF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,391,670 - 112,410,160 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,827,451 - 111,846,482 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01113,015,057 - 113,034,087 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1113,015,059 - 113,033,980 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,568,393 - 112,587,492 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01112,204,579 - 112,223,608 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01113,131,063 - 113,150,095 (-)NCBIUU_Cfam_GSD_1.0
Arhgef1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934916,193,641 - 16,211,488 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936706540,748 - 558,823 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936706540,987 - 558,792 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGEF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl649,975,876 - 49,995,339 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1649,975,957 - 49,995,442 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2646,030,643 - 46,046,982 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGEF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,091,158 - 36,115,355 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl636,091,204 - 36,115,626 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607314,326,794 - 14,351,774 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgef1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907783,214 - 802,150 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624907783,404 - 802,205 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arhgef1
754 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2826
Count of miRNA genes:716
Interacting mature miRNAs:916
Transcripts:ENSMUST00000047873, ENSMUST00000098683, ENSMUST00000117419, ENSMUST00000117796, ENSMUST00000126484, ENSMUST00000126918, ENSMUST00000127761, ENSMUST00000129383, ENSMUST00000129928, ENSMUST00000132751, ENSMUST00000132786, ENSMUST00000144714, ENSMUST00000145783, ENSMUST00000151121
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
1301115Lrdm1_mlymphoproliferation (Fas) renal disease modifier 1 (mouse)Not determined7335204824879418Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001130150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001130151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001130152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001130153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_182017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_182018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004934023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC161441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY246272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY246273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB840025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY323306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA320228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF169826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV783191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U58203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U89421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000047873   ⟹   ENSMUSP00000046469
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,602,462 - 24,626,014 (+)Ensembl
GRCm38.p6 Ensembl724,903,037 - 24,926,589 (+)Ensembl
Ensembl Acc Id: ENSMUST00000098683   ⟹   ENSMUSP00000096280
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,602,476 - 24,626,014 (+)Ensembl
GRCm38.p6 Ensembl724,903,051 - 24,926,589 (+)Ensembl
Ensembl Acc Id: ENSMUST00000117419   ⟹   ENSMUSP00000113366
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,603,832 - 24,626,017 (+)Ensembl
GRCm38.p6 Ensembl724,904,407 - 24,926,592 (+)Ensembl
Ensembl Acc Id: ENSMUST00000117796   ⟹   ENSMUSP00000113771
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,602,337 - 24,626,017 (+)Ensembl
GRCm38.p6 Ensembl724,902,912 - 24,926,592 (+)Ensembl
Ensembl Acc Id: ENSMUST00000126484
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,622,673 - 24,624,272 (+)Ensembl
GRCm38.p6 Ensembl724,923,248 - 24,924,847 (+)Ensembl
Ensembl Acc Id: ENSMUST00000126918
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,622,778 - 24,624,910 (+)Ensembl
GRCm38.p6 Ensembl724,923,353 - 24,925,485 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127761
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,602,500 - 24,609,385 (+)Ensembl
GRCm38.p6 Ensembl724,903,075 - 24,909,960 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129383
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,602,490 - 24,603,809 (+)Ensembl
GRCm38.p6 Ensembl724,903,065 - 24,904,384 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129928
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,618,627 - 24,621,804 (+)Ensembl
GRCm38.p6 Ensembl724,919,202 - 24,922,379 (+)Ensembl
Ensembl Acc Id: ENSMUST00000132751   ⟹   ENSMUSP00000117008
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,616,256 - 24,625,531 (+)Ensembl
GRCm38.p6 Ensembl724,916,831 - 24,926,106 (+)Ensembl
Ensembl Acc Id: ENSMUST00000132786
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,622,788 - 24,625,361 (+)Ensembl
GRCm38.p6 Ensembl724,923,363 - 24,925,936 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144714
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,612,042 - 24,617,817 (+)Ensembl
GRCm38.p6 Ensembl724,912,617 - 24,918,392 (+)Ensembl
Ensembl Acc Id: ENSMUST00000145783
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,603,783 - 24,626,014 (+)Ensembl
GRCm38.p6 Ensembl724,904,358 - 24,926,589 (+)Ensembl
Ensembl Acc Id: ENSMUST00000151121   ⟹   ENSMUSP00000114388
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,607,072 - 24,611,565 (+)Ensembl
GRCm38.p6 Ensembl724,907,647 - 24,912,140 (+)Ensembl
Ensembl Acc Id: ENSMUST00000205295   ⟹   ENSMUSP00000146059
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,603,865 - 24,622,516 (+)Ensembl
GRCm38.p6 Ensembl724,904,440 - 24,923,091 (+)Ensembl
Ensembl Acc Id: ENSMUST00000206011   ⟹   ENSMUSP00000145981
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,603,830 - 24,612,025 (+)Ensembl
GRCm38.p6 Ensembl724,904,405 - 24,912,600 (+)Ensembl
Ensembl Acc Id: ENSMUST00000206028   ⟹   ENSMUSP00000145659
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,602,496 - 24,607,317 (+)Ensembl
GRCm38.p6 Ensembl724,903,071 - 24,907,892 (+)Ensembl
Ensembl Acc Id: ENSMUST00000206508   ⟹   ENSMUSP00000146314
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,602,481 - 24,626,019 (+)Ensembl
GRCm38.p6 Ensembl724,903,056 - 24,926,594 (+)Ensembl
Ensembl Acc Id: ENSMUST00000206906   ⟹   ENSMUSP00000146065
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl724,603,781 - 24,612,876 (+)Ensembl
GRCm38.p6 Ensembl724,904,356 - 24,913,451 (+)Ensembl
RefSeq Acc Id: NM_001130150   ⟹   NP_001123622
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,447 - 24,626,017 (+)NCBI
GRCm38724,902,986 - 24,926,592 (+)NCBI
MGSCv37725,688,005 - 25,711,611 (+)RGD
Celera719,518,885 - 19,542,623 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001130151   ⟹   NP_001123623
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,447 - 24,626,017 (+)NCBI
GRCm38724,902,986 - 24,926,592 (+)NCBI
MGSCv37725,688,005 - 25,711,611 (+)RGD
Celera719,518,885 - 19,542,623 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001130152   ⟹   NP_001123624
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,603,797 - 24,626,017 (+)NCBI
GRCm38724,904,346 - 24,926,592 (+)NCBI
MGSCv37725,688,005 - 25,711,611 (+)RGD
Celera719,518,885 - 19,542,623 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001130153   ⟹   NP_001123625
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,447 - 24,626,017 (+)NCBI
GRCm38724,902,986 - 24,926,592 (+)NCBI
MGSCv37725,688,005 - 25,711,611 (+)RGD
Celera719,518,885 - 19,542,623 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001412640   ⟹   NP_001399569
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,603,797 - 24,626,017 (+)NCBI
RefSeq Acc Id: NM_001412641   ⟹   NP_001399570
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,447 - 24,626,017 (+)NCBI
RefSeq Acc Id: NM_001412642   ⟹   NP_001399571
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,447 - 24,626,017 (+)NCBI
RefSeq Acc Id: NM_001412643   ⟹   NP_001399572
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,447 - 24,626,017 (+)NCBI
RefSeq Acc Id: NM_001412644   ⟹   NP_001399573
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,603,797 - 24,626,017 (+)NCBI
RefSeq Acc Id: NM_001412645   ⟹   NP_001399574
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,603,797 - 24,626,017 (+)NCBI
RefSeq Acc Id: NM_001412646   ⟹   NP_001399575
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,447 - 24,626,017 (+)NCBI
RefSeq Acc Id: NM_001412647   ⟹   NP_001399576
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,447 - 24,626,017 (+)NCBI
RefSeq Acc Id: NM_001412648   ⟹   NP_001399577
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,447 - 24,626,017 (+)NCBI
RefSeq Acc Id: NM_001412649   ⟹   NP_001399578
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,603,797 - 24,626,017 (+)NCBI
RefSeq Acc Id: NM_008488   ⟹   NP_032514
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,447 - 24,626,017 (+)NCBI
GRCm38724,902,986 - 24,926,592 (+)NCBI
MGSCv37725,688,005 - 25,711,611 (+)RGD
Celera719,518,885 - 19,542,623 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_182017
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,447 - 24,626,017 (+)NCBI
RefSeq Acc Id: NR_182018
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,603,797 - 24,626,017 (+)NCBI
RefSeq Acc Id: XM_006539565   ⟹   XP_006539628
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,603,419 - 24,626,019 (+)NCBI
GRCm38724,903,994 - 24,926,594 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322003   ⟹   XP_017177492
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,602,859 - 24,626,019 (+)NCBI
GRCm38724,903,434 - 24,926,594 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030242173   ⟹   XP_030098033
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,603,418 - 24,626,019 (+)NCBI
GRCm38724,903,993 - 24,926,594 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152721   ⟹   XP_036008614
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,601,762 - 24,626,019 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004934023
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39724,601,762 - 24,626,019 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001123622 (Get FASTA)   NCBI Sequence Viewer  
  NP_001123623 (Get FASTA)   NCBI Sequence Viewer  
  NP_001123624 (Get FASTA)   NCBI Sequence Viewer  
  NP_001123625 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399569 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399570 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399571 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399572 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399573 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399574 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399575 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399576 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399577 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399578 (Get FASTA)   NCBI Sequence Viewer  
  NP_032514 (Get FASTA)   NCBI Sequence Viewer  
  XP_006539628 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177492 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098033 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008614 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC36527 (Get FASTA)   NCBI Sequence Viewer  
  AAC52693 (Get FASTA)   NCBI Sequence Viewer  
  AAH12488 (Get FASTA)   NCBI Sequence Viewer  
  AAO91658 (Get FASTA)   NCBI Sequence Viewer  
  AAO91659 (Get FASTA)   NCBI Sequence Viewer  
  BAC30509 (Get FASTA)   NCBI Sequence Viewer  
  BAD21431 (Get FASTA)   NCBI Sequence Viewer  
  BAE33947 (Get FASTA)   NCBI Sequence Viewer  
  BAE42963 (Get FASTA)   NCBI Sequence Viewer  
  EDL24302 (Get FASTA)   NCBI Sequence Viewer  
  EDL24303 (Get FASTA)   NCBI Sequence Viewer  
  EDL24304 (Get FASTA)   NCBI Sequence Viewer  
  EDL24305 (Get FASTA)   NCBI Sequence Viewer  
  EDL24306 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000046469
  ENSMUSP00000046469.10
  ENSMUSP00000096280
  ENSMUSP00000096280.5
  ENSMUSP00000113366
  ENSMUSP00000113366.2
  ENSMUSP00000113771
  ENSMUSP00000113771.2
  ENSMUSP00000114388.2
  ENSMUSP00000117008.2
  ENSMUSP00000145659.2
  ENSMUSP00000145981.2
  ENSMUSP00000146059.2
  ENSMUSP00000146065.2
  ENSMUSP00000146314
  ENSMUSP00000146314.2
GenBank Protein Q61210 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_032514   ⟸   NM_008488
- Peptide Label: isoform d
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001123622   ⟸   NM_001130150
- Peptide Label: isoform a
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001123623   ⟸   NM_001130151
- Peptide Label: isoform b
- UniProtKB: E9PUF7 (UniProtKB/TrEMBL),   Q6KAM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001123625   ⟸   NM_001130153
- Peptide Label: isoform c
- UniProtKB: Q80YE9 (UniProtKB/Swiss-Prot),   Q80YE8 (UniProtKB/Swiss-Prot),   Q3T9Q7 (UniProtKB/Swiss-Prot),   O89074 (UniProtKB/Swiss-Prot),   Q91VL3 (UniProtKB/Swiss-Prot),   Q61210 (UniProtKB/Swiss-Prot),   Q6KAM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001123624   ⟸   NM_001130152
- Peptide Label: isoform c
- UniProtKB: Q80YE9 (UniProtKB/Swiss-Prot),   Q80YE8 (UniProtKB/Swiss-Prot),   Q3T9Q7 (UniProtKB/Swiss-Prot),   O89074 (UniProtKB/Swiss-Prot),   Q91VL3 (UniProtKB/Swiss-Prot),   Q61210 (UniProtKB/Swiss-Prot),   Q6KAM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006539628   ⟸   XM_006539565
- Peptide Label: isoform X1
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017177492   ⟸   XM_017322003
- Peptide Label: isoform X1
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030098033   ⟸   XM_030242173
- Peptide Label: isoform X2
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000145659   ⟸   ENSMUST00000206028
Ensembl Acc Id: ENSMUSP00000145981   ⟸   ENSMUST00000206011
Ensembl Acc Id: ENSMUSP00000146065   ⟸   ENSMUST00000206906
Ensembl Acc Id: ENSMUSP00000146314   ⟸   ENSMUST00000206508
Ensembl Acc Id: ENSMUSP00000117008   ⟸   ENSMUST00000132751
Ensembl Acc Id: ENSMUSP00000146059   ⟸   ENSMUST00000205295
Ensembl Acc Id: ENSMUSP00000046469   ⟸   ENSMUST00000047873
Ensembl Acc Id: ENSMUSP00000114388   ⟸   ENSMUST00000151121
Ensembl Acc Id: ENSMUSP00000096280   ⟸   ENSMUST00000098683
Ensembl Acc Id: ENSMUSP00000113366   ⟸   ENSMUST00000117419
Ensembl Acc Id: ENSMUSP00000113771   ⟸   ENSMUST00000117796
RefSeq Acc Id: XP_036008614   ⟸   XM_036152721
- Peptide Label: isoform X1
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399570   ⟸   NM_001412641
- Peptide Label: isoform b
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL),   E9PUF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399571   ⟸   NM_001412642
- Peptide Label: isoform b
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL),   E9PUF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399572   ⟸   NM_001412643
- Peptide Label: isoform c
- UniProtKB: Q80YE9 (UniProtKB/Swiss-Prot),   Q80YE8 (UniProtKB/Swiss-Prot),   Q61210 (UniProtKB/Swiss-Prot),   Q3T9Q7 (UniProtKB/Swiss-Prot),   O89074 (UniProtKB/Swiss-Prot),   Q91VL3 (UniProtKB/Swiss-Prot),   Q6KAM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399575   ⟸   NM_001412646
- Peptide Label: isoform e
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399576   ⟸   NM_001412647
- Peptide Label: isoform f
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399577   ⟸   NM_001412648
- Peptide Label: isoform g
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399569   ⟸   NM_001412640
- Peptide Label: isoform b
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL),   E9PUF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399574   ⟸   NM_001412645
- Peptide Label: isoform e
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399573   ⟸   NM_001412644
- Peptide Label: isoform d
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399578   ⟸   NM_001412649
- Peptide Label: isoform g
- UniProtKB: Q6KAM6 (UniProtKB/TrEMBL)
Protein Domains
DH   PH   Regulator of G protein signalling-like   RGSL

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61210-F1-model_v2 AlphaFold Q61210 1-920 view protein structure

Promoters
RGD ID:6892224
Promoter ID:EPDNEW_M9563
Type:initiation region
Name:Arhgef1_1
Description:Mus musculus Rho guanine nucleotide exchange factor 1 , transcriptvariant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9564  EPDNEW_M9565  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38724,903,037 - 24,903,097EPDNEW
RGD ID:6892226
Promoter ID:EPDNEW_M9564
Type:initiation region
Name:Arhgef1_2
Description:Mus musculus Rho guanine nucleotide exchange factor 1 , transcriptvariant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9563  EPDNEW_M9565  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38724,904,405 - 24,904,465EPDNEW
RGD ID:6892228
Promoter ID:EPDNEW_M9565
Type:multiple initiation site
Name:Arhgef1_3
Description:Mus musculus Rho guanine nucleotide exchange factor 1 , transcriptvariant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9563  EPDNEW_M9564  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38724,907,319 - 24,907,379EPDNEW
RGD ID:6840665
Promoter ID:MM_KWN:49403
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000108423,   ENSMUST00000117796,   NM_001130150,   NM_001130153,   NM_008488,   OTTMUST00000072545,   UC009FQU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36725,687,516 - 25,688,197 (+)MPROMDB
RGD ID:6840638
Promoter ID:MM_KWN:49404
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000108424,   ENSMUST00000117419,   OTTMUST00000072542
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36725,689,089 - 25,689,589 (+)MPROMDB
RGD ID:6840639
Promoter ID:MM_KWN:49405
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   Lung,   Spleen
Transcripts:OTTMUST00000072546
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36725,691,846 - 25,692,702 (+)MPROMDB
RGD ID:6840641
Promoter ID:MM_KWN:49406
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Liver,   Lung,   Spleen
Transcripts:UC009FRA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36725,692,396 - 25,693,717 (+)MPROMDB
RGD ID:6840640
Promoter ID:MM_KWN:49407
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   Spleen
Transcripts:OTTMUST00000072547
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36725,696,906 - 25,697,802 (+)MPROMDB
RGD ID:6840642
Promoter ID:MM_KWN:49409
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Lung
Transcripts:OTTMUST00000072548
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36725,703,246 - 25,704,392 (+)MPROMDB
RGD ID:6840661
Promoter ID:MM_KWN:49410
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Lung,   Spleen
Transcripts:OTTMUST00000072549,   OTTMUST00000072550,   OTTMUST00000072551,   UC009FRB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36725,707,606 - 25,708,847 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1353510 AgrOrtholog
Ensembl Genes ENSMUSG00000040940 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000047873 ENTREZGENE
  ENSMUST00000047873.16 UniProtKB/Swiss-Prot
  ENSMUST00000098683 ENTREZGENE
  ENSMUST00000098683.11 UniProtKB/Swiss-Prot
  ENSMUST00000117419 ENTREZGENE
  ENSMUST00000117419.8 UniProtKB/Swiss-Prot
  ENSMUST00000117796 ENTREZGENE
  ENSMUST00000117796.8 UniProtKB/TrEMBL
  ENSMUST00000132751.2 UniProtKB/TrEMBL
  ENSMUST00000145783 ENTREZGENE
  ENSMUST00000151121.2 UniProtKB/TrEMBL
  ENSMUST00000205295.2 UniProtKB/TrEMBL
  ENSMUST00000206011.2 UniProtKB/TrEMBL
  ENSMUST00000206028.2 UniProtKB/TrEMBL
  ENSMUST00000206508 ENTREZGENE
  ENSMUST00000206508.2 UniProtKB/Swiss-Prot
  ENSMUST00000206906.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.900.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DH-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p115RhoGEF_RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16801 UniProtKB/Swiss-Prot
MGD MGI:1353510 ENTREZGENE
NCBI Gene 16801 ENTREZGENE
PANTHER RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PH_16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arhgef1 PhenoGen
PROSITE DH_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48065 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48097 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0U1RNQ2_MOUSE UniProtKB/TrEMBL
  A0A0U1RPH2_MOUSE UniProtKB/TrEMBL
  A0A0U1RPN7_MOUSE UniProtKB/TrEMBL
  A0A0U1RPP2_MOUSE UniProtKB/TrEMBL
  ARHG1_MOUSE UniProtKB/Swiss-Prot
  D3YVJ9_MOUSE UniProtKB/TrEMBL
  E9PUF7 ENTREZGENE, UniProtKB/TrEMBL
  F6ZN61_MOUSE UniProtKB/TrEMBL
  O89074 ENTREZGENE
  Q3T9Q7 ENTREZGENE
  Q61210 ENTREZGENE
  Q6KAM6 ENTREZGENE, UniProtKB/TrEMBL
  Q80YE8 ENTREZGENE
  Q80YE9 ENTREZGENE
  Q8CA02_MOUSE UniProtKB/TrEMBL
  Q91VL3 ENTREZGENE
UniProt Secondary O89074 UniProtKB/Swiss-Prot
  Q3T9Q7 UniProtKB/Swiss-Prot
  Q80YE8 UniProtKB/Swiss-Prot
  Q80YE9 UniProtKB/Swiss-Prot
  Q91VL3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Arhgef1  Rho guanine nucleotide exchange factor 1  Arhgef1  Rho guanine nucleotide exchange factor (GEF) 1  Symbol and/or name change 5135510 APPROVED