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Gene: Fbxo7 (F-box protein 7) Mus musculus
Symbol: Fbxo7
Name: F-box protein 7
RGD ID: 1313801
Description: Exhibits protein kinase binding activity. Involved in negative regulation of G1/S transition of mitotic cell cycle; negative regulation of cyclin-dependent protein serine/threonine kinase activity; and negative regulation of lymphocyte differentiation. Localizes to mitochondrion and nucleus. Is expressed in dorsal root ganglion; gallbladder; liver; trigeminal ganglion; and vagus ganglion. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 15. Orthologous to human FBXO7 (F-box protein 7); PARTICIPATES IN Parkinson's disease pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410015K21Rik; A230052G17Rik; AI117679; AW260462; C85118; F-box only protein 7
Homo sapiens (human) : FBXO7 (F-box protein 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxo7 (F-box protein 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo7 (F-box protein 7)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO7 (F-box protein 7)
Canis lupus familiaris (dog) : FBXO7 (F-box protein 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo7 (F-box protein 7)
Sus scrofa (pig) : FBXO7 (F-box protein 7)
Chlorocebus sabaeus (African green monkey) : FBXO7 (F-box protein 7)
Heterocephalus glaber (naked mole-rat) : Fbxo7 (F-box protein 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391085,856,313 - 85,887,737 (+)NCBI
GRCm381086,020,449 - 86,051,873 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1086,021,972 - 86,051,873 (+)EnsemblGRCm38mm10GRCm38
MGSCv371085,484,674 - 85,511,073 (+)NCBIGRCm37mm9NCBIm37
MGSCv361085,451,796 - 85,478,128 (+)NCBImm8
Celera1087,995,701 - 88,022,106 (+)NCBICelera
Cytogenetic Map10C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fbxo7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313801
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.