Fbxo7 (F-box protein 7) - Rat Genome Database

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Gene: Fbxo7 (F-box protein 7) Mus musculus
Analyze
Symbol: Fbxo7
Name: F-box protein 7
RGD ID: 1313801
MGI Page MGI
Description: Enables protein kinase binding activity. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle; negative regulation of cyclin-dependent protein serine/threonine kinase activity; and negative regulation of lymphocyte differentiation. Located in mitochondrion and nucleus. Is expressed in dorsal root ganglion; gallbladder; liver; trigeminal ganglion; and vagus ganglion. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 15. Orthologous to human FBXO7 (F-box protein 7).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2410015K21Rik; A230052G17Rik; AI117679; AW260462; C85118; F-box only protein 7
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391085,856,313 - 85,887,737 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1085,857,836 - 85,887,737 (+)EnsemblGRCm39 Ensembl
GRCm381086,020,449 - 86,051,873 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1086,021,972 - 86,051,873 (+)EnsemblGRCm38mm10GRCm38
MGSCv371085,484,674 - 85,511,073 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361085,451,796 - 85,478,128 (+)NCBIMGSCv36mm8
Celera1087,995,701 - 88,022,106 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1041.91NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal effector T cell number  (IAGP)
abnormal proerythroblast morphology  (IAGP)
abnormal reticulocyte cell number  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal T cell differentiation  (IAGP)
anemia  (IAGP)
anisocytosis  (IAGP)
arrest of spermiogenesis  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased circulating fructosamine level  (IEA)
decreased circulating iron level  (IAGP)
decreased erythroblast number  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased hematocrit  (IAGP)
decreased hemoglobin content  (IAGP)
decreased leukocyte cell number  (IEA)
decreased T cell number  (IAGP)
decreased testis weight  (IAGP)
enlarged spleen  (IAGP)
extramedullary hematopoiesis  (IAGP)
hyperchromic macrocytic anemia  (IAGP)
immotile sperm  (IAGP)
increased activated T cell number  (IAGP)
increased circulating bilirubin level  (IAGP)
increased circulating sodium level  (IEA)
increased double-negative T cell number  (IAGP)
increased effector memory CD4-positive, alpha-beta T cell number  (IAGP)
increased effector memory CD8-positive, alpha-beta T cell number  (IAGP)
increased erythroblast number  (IAGP)
increased erythrocyte clearance  (IAGP)
increased erythroid progenitor cell number  (IAGP)
increased mean corpuscular hemoglobin  (IEA)
increased mean corpuscular hemoglobin concentration  (IAGP)
increased mean corpuscular volume  (IAGP)
increased memory T cell number  (IAGP)
increased pro-B cell number  (IAGP)
increased red blood cell distribution width  (IAGP)
increased spleen weight  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
increased susceptibility to bacterial infection induced morbidity/mortality  (IAGP)
male infertility  (IAGP)
oligozoospermia  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
reticulocytosis  (IAGP)
teratozoospermia  (IAGP)
thrombocytosis  (IEA)
thymus atrophy  (IAGP)
thymus hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Genes associated with Parkinson's disease: regulation of autophagy and beyond. Beilina A and Cookson MR, J Neurochem. 2015 Jul 30. doi: 10.1111/jnc.13266.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:11544199   PMID:12466851   PMID:12477932   PMID:12520002  
PMID:14610273   PMID:15782199   PMID:16096642   PMID:16141072   PMID:16141073   PMID:16783635   PMID:21267068   PMID:21652635   PMID:21677750   PMID:21873635   PMID:25526474   PMID:26095538  
PMID:26310625   PMID:27497298   PMID:27915416   PMID:30840666   PMID:30973865   PMID:31085610   PMID:31144295   PMID:31649556   PMID:32245826   PMID:32325033   PMID:32493843   PMID:33291077  
PMID:34800438   PMID:35670764   PMID:35701754   PMID:37753846   PMID:38355793  


Genomics

Comparative Map Data
Fbxo7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391085,856,313 - 85,887,737 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1085,857,836 - 85,887,737 (+)EnsemblGRCm39 Ensembl
GRCm381086,020,449 - 86,051,873 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1086,021,972 - 86,051,873 (+)EnsemblGRCm38mm10GRCm38
MGSCv371085,484,674 - 85,511,073 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361085,451,796 - 85,478,128 (+)NCBIMGSCv36mm8
Celera1087,995,701 - 88,022,106 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1041.91NCBI
FBXO7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382232,474,811 - 32,498,829 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2232,474,676 - 32,498,829 (+)EnsemblGRCh38hg38GRCh38
GRCh372232,870,798 - 32,894,816 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362231,200,707 - 31,224,818 (+)NCBINCBI36Build 36hg18NCBI36
Build 342231,195,263 - 31,219,369NCBI
Celera2216,672,879 - 16,696,990 (+)NCBICelera
Cytogenetic Map22q12.3NCBI
HuRef2215,827,931 - 15,852,000 (+)NCBIHuRef
CHM1_12232,830,063 - 32,854,178 (+)NCBICHM1_1
T2T-CHM13v2.02232,938,705 - 32,962,724 (+)NCBIT2T-CHM13v2.0
Fbxo7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8719,696,951 - 19,725,180 (-)NCBIGRCr8
mRatBN7.2717,809,224 - 17,837,549 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl717,809,231 - 17,837,530 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx719,771,322 - 19,799,547 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0721,928,523 - 21,956,738 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0721,710,970 - 21,739,195 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0723,815,246 - 23,843,505 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl723,815,245 - 23,843,634 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0723,964,601 - 23,993,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4719,947,498 - 19,975,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1719,960,416 - 19,988,648 (-)NCBI
Celera715,042,489 - 15,070,722 (-)NCBICelera
Cytogenetic Map7q13NCBI
Fbxo7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540541,433,082 - 41,453,909 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540541,429,421 - 41,449,670 (+)NCBIChiLan1.0ChiLan1.0
FBXO7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22342,411,197 - 42,435,546 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12245,111,484 - 45,135,854 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02213,481,255 - 13,505,301 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12231,335,423 - 31,359,224 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2231,335,423 - 31,359,224 (+)Ensemblpanpan1.1panPan2
FBXO7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11030,928,059 - 30,948,858 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1030,928,329 - 30,948,977 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1030,910,928 - 30,931,963 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01031,770,136 - 31,791,111 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1031,770,138 - 31,791,130 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11031,510,102 - 31,530,961 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01031,799,411 - 31,820,248 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01031,985,722 - 32,006,997 (-)NCBIUU_Cfam_GSD_1.0
Fbxo7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494514,251,029 - 14,266,764 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364927,261,009 - 7,276,943 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364927,261,442 - 7,276,779 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl512,505,654 - 12,526,232 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1512,505,646 - 12,526,206 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2512,291,445 - 12,313,045 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11915,300,135 - 15,324,256 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1915,300,158 - 15,323,956 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045110,683,150 - 110,707,342 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247501,977,761 - 1,997,231 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247501,977,666 - 1,997,408 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fbxo7
851 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2360
Count of miRNA genes:824
Interacting mature miRNAs:1121
Transcripts:ENSMUST00000001837, ENSMUST00000117597, ENSMUST00000120344, ENSMUST00000130320, ENSMUST00000130383, ENSMUST00000134490, ENSMUST00000147168
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106684818792258673Mouse
12910789Pwgrq19_mpost-weaning growth rate QTL 19 (mouse)108282870092169056Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75338568109338767Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105851696992517096Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
14746991Manh68_mmandible shape 68 (mouse)105228049786280497Mouse
1357594Estoq3_membryo survival total QTL 3 (mouse)Not determined1084079650122041528Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
4141479W10q8_mweight 10 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
14700795Mencq7_mmeniscus calcification QTL 7 (mouse)108531386486647864Mouse
14747004Mancz8_mmandible centroid size 8 (mouse)1082078412116078412Mouse
4142496W6q8_mweight 6 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073506901107507047Mouse
1357622Espq3_membryo survival preimplantation QTL 3 (mouse)Not determined1084079650122041528Mouse
4142365Egq9_mearly growth QTL 9 (mouse)Not determined84079650122041528Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106549093899491121Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078381268112381268Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
1301165Lith7_mlithogenic gene 7 (mouse)Not determined1082309418116309657Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106549093899491121Mouse
4141054mwfh_mmodifier of white forlock hypopigmentation (mouse)Not determined83017003117017136Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067335830111735905Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
1357779Tesq3_mtestis weight QTL 3 (mouse)Not determined1084079650122041528Mouse
11059553Lmr32d_mleishmaniasis resistance 32d (mouse)1082309418116309657Mouse
11059554Lmr32e_mleishmaniasis resistance 32e (mouse)1082309418116309657Mouse
11059555Lmr32f_mleishmaniasis resistance 32f (mouse)1082309418116309657Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1063935779115935905Mouse
1357638Cia29_mcollagen induced arthritis 29 (mouse)Not determined1085454982118497353Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075338568109338767Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
10043881Adip24_madiposity 24 (mouse)Not determined1082392803116392952Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
4141387Lgaq5_mlate growth adjusted QTL 5 (mouse)Not determined84079650122041528Mouse
11059550Lmr32a_mleishmaniasis resistance 32a (mouse)1082309418116309657Mouse
11059551Lmr32b_mleishmaniasis resistance 32b (mouse)1082309418116309657Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
4141382Ssrq4_mstress response QTL 4 (mouse)Not determined8249093890856102Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106549093899491121Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075338568109338767Mouse

Markers in Region
RH127130  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381086,048,104 - 86,048,303UniSTSGRCm38
MGSCv371085,510,849 - 85,511,048UniSTSGRCm37
Celera1088,021,882 - 88,022,081UniSTS
Cytogenetic Map10C1UniSTS
Whitehead/MRC_RH10974.86UniSTS
AW260462  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381086,049,059 - 86,049,169UniSTSGRCm38
MGSCv371085,511,804 - 85,511,914UniSTSGRCm37
Celera1088,022,837 - 88,022,947UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map10C1UniSTS
Whitehead/MRC_RH10974.86UniSTS
AI117679  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381086,048,964 - 86,049,169UniSTSGRCm38
MGSCv371085,511,709 - 85,511,914UniSTSGRCm37
Celera1088,022,742 - 88,022,947UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map10C1UniSTS
Whitehead/MRC_RH10974.19UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001310745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001347151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_153195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017314077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC122919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI447461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD563204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000001837   ⟹   ENSMUSP00000001837
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1085,857,851 - 85,884,157 (+)Ensembl
GRCm38.p6 Ensembl1086,021,987 - 86,048,293 (+)Ensembl
Ensembl Acc Id: ENSMUST00000117597   ⟹   ENSMUSP00000113263
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1085,858,061 - 85,884,187 (+)Ensembl
GRCm38.p6 Ensembl1086,022,197 - 86,048,323 (+)Ensembl
Ensembl Acc Id: ENSMUST00000120344   ⟹   ENSMUSP00000113222
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1085,858,053 - 85,884,187 (+)Ensembl
GRCm38.p6 Ensembl1086,022,189 - 86,048,323 (+)Ensembl
Ensembl Acc Id: ENSMUST00000130320   ⟹   ENSMUSP00000120840
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1085,857,836 - 85,887,737 (+)Ensembl
GRCm38.p6 Ensembl1086,021,972 - 86,051,873 (+)Ensembl
Ensembl Acc Id: ENSMUST00000130383
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1085,878,316 - 85,882,673 (+)Ensembl
GRCm38.p6 Ensembl1086,042,452 - 86,046,809 (+)Ensembl
Ensembl Acc Id: ENSMUST00000134490
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1085,868,835 - 85,887,735 (+)Ensembl
GRCm38.p6 Ensembl1086,032,971 - 86,051,871 (+)Ensembl
Ensembl Acc Id: ENSMUST00000147168   ⟹   ENSMUSP00000119334
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1085,857,883 - 85,864,988 (+)Ensembl
GRCm38.p6 Ensembl1086,022,019 - 86,029,124 (+)Ensembl
RefSeq Acc Id: NM_001310745   ⟹   NP_001297674
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391085,858,018 - 85,884,192 (+)NCBI
GRCm381086,022,154 - 86,048,328 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001347151   ⟹   NP_001334080
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391085,858,018 - 85,887,737 (+)NCBI
GRCm381086,022,154 - 86,051,873 (+)NCBI
Sequence:
RefSeq Acc Id: NM_153195   ⟹   NP_694875
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391085,857,793 - 85,884,192 (+)NCBI
GRCm381086,021,929 - 86,048,328 (+)NCBI
MGSCv371085,484,674 - 85,511,073 (+)RGD
Celera1087,995,701 - 88,022,106 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011243556   ⟹   XP_011241858
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391085,857,695 - 85,884,200 (+)NCBI
GRCm381086,021,831 - 86,048,336 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017314077   ⟹   XP_017169566
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391085,856,313 - 85,884,200 (+)NCBI
GRCm381086,020,449 - 86,048,336 (+)NCBI
Sequence:
RefSeq Acc Id: NP_694875   ⟸   NM_153195
- Peptide Label: isoform 1
- UniProtKB: Q3UBC1 (UniProtKB/Swiss-Prot),   Q8K0A5 (UniProtKB/Swiss-Prot),   Q3U7U3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011241858   ⟸   XM_011243556
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017169566   ⟸   XM_017314077
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001297674   ⟸   NM_001310745
- Peptide Label: isoform 2
- UniProtKB: Q3UD93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001334080   ⟸   NM_001347151
- Peptide Label: isoform 3
- UniProtKB: Q3UGI9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000120840   ⟸   ENSMUST00000130320
Ensembl Acc Id: ENSMUSP00000119334   ⟸   ENSMUST00000147168
Ensembl Acc Id: ENSMUSP00000113222   ⟸   ENSMUST00000120344
Ensembl Acc Id: ENSMUSP00000001837   ⟸   ENSMUST00000001837
Ensembl Acc Id: ENSMUSP00000113263   ⟸   ENSMUST00000117597
Protein Domains
F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3U7U3-F1-model_v2 AlphaFold Q3U7U3 1-523 view protein structure

Promoters
RGD ID:6819280
Promoter ID:MM_KWN:5194
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   MEF_B4
Transcripts:OTTMUST00000071033,   OTTMUST00000071038,   OTTMUST00000071039,   UC007GNL.1,   UC007GNM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361085,484,544 - 85,485,044 (+)MPROMDB
RGD ID:6819282
Promoter ID:MM_KWN:5195
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000071036
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361085,495,451 - 85,495,951 (+)MPROMDB
RGD ID:6819283
Promoter ID:MM_KWN:5197
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000071037
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361085,504,851 - 85,505,351 (+)MPROMDB
RGD ID:8672932
Promoter ID:EPDNEW_M14497
Type:initiation region
Name:Fbxo7_1
Description:Mus musculus F-box protein 7 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14498  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381086,021,972 - 86,022,032EPDNEW
RGD ID:8672934
Promoter ID:EPDNEW_M14498
Type:multiple initiation site
Name:Fbxo7_2
Description:Mus musculus F-box protein 7 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14497  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381086,022,121 - 86,022,181EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917004 AgrOrtholog
Ensembl Genes ENSMUSG00000001786 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000001837.14 UniProtKB/TrEMBL
  ENSMUST00000117597 ENTREZGENE
  ENSMUST00000117597.2 UniProtKB/TrEMBL
  ENSMUST00000120344 ENTREZGENE
  ENSMUST00000120344.8 UniProtKB/TrEMBL
  ENSMUST00000130320 ENTREZGENE
  ENSMUST00000130320.8 UniProtKB/Swiss-Prot
  ENSMUST00000147168.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.1000.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro F-box-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-box_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fbxo7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI31_Prot_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report mmu:69754 UniProtKB/Swiss-Prot
MGD MGI:1917004 ENTREZGENE
NCBI Gene 69754 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 7 UniProtKB/Swiss-Prot
  F-BOX ONLY PROTEIN 7 UniProtKB/Swiss-Prot
  F-BOX ONLY PROTEIN 7 UniProtKB/TrEMBL
  F-BOX ONLY PROTEIN 7 UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI31_Prot_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fbxo7 PhenoGen
PROSITE FBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/Swiss-Prot
  SSF81383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D6RJ76_MOUSE UniProtKB/TrEMBL
  F8WIP1_MOUSE UniProtKB/TrEMBL
  FBX7_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UBC1 ENTREZGENE
  Q3UD93 ENTREZGENE, UniProtKB/TrEMBL
  Q3UGI9 ENTREZGENE, UniProtKB/TrEMBL
  Q8K0A5 ENTREZGENE
UniProt Secondary Q3UBC1 UniProtKB/Swiss-Prot
  Q8K0A5 UniProtKB/Swiss-Prot