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Gene: Fbxo7 (F-box protein 7) Mus musculus
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Symbol: Fbxo7
Name: F-box protein 7
RGD ID: 1313801
Description: Exhibits protein kinase binding activity. Involved in negative regulation of G1/S transition of mitotic cell cycle; negative regulation of cyclin-dependent protein serine/threonine kinase activity; and negative regulation of lymphocyte differentiation. Localizes to mitochondrion and nucleus. Is expressed in dorsal root ganglion; gallbladder; liver; trigeminal ganglion; and vagus ganglion. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 15. Orthologous to human FBXO7 (F-box protein 7); PARTICIPATES IN Parkinson's disease pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410015K21Rik; A230052G17Rik; AI117679; AW260462; C85118; F-box only protein 7
Orthologs:
Homo sapiens (human) : FBXO7 (F-box protein 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxo7 (F-box protein 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo7 (F-box protein 7)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO7 (F-box protein 7)
Canis lupus familiaris (dog) : FBXO7 (F-box protein 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo7 (F-box protein 7)
Sus scrofa (pig) : FBXO7 (F-box protein 7)
Chlorocebus sabaeus (African green monkey) : FBXO7 (F-box protein 7)
Heterocephalus glaber (naked mole-rat) : Fbxo7 (F-box protein 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391085,856,313 - 85,887,737 (+)NCBI
GRCm381086,020,449 - 86,051,873 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1086,021,972 - 86,051,873 (+)EnsemblGRCm38mm10GRCm38
MGSCv371085,484,674 - 85,511,073 (+)NCBIGRCm37mm9NCBIm37
MGSCv361085,451,796 - 85,478,128 (+)NCBImm8
Celera1087,995,701 - 88,022,106 (+)NCBICelera
Cytogenetic Map10C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fbxo7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313801
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.