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Gene: FBXO7 (F-box protein 7) Homo sapiens
Symbol: FBXO7
Name: F-box protein 7
Description: Exhibits several functions, including enzyme binding activity; protein heterodimerization activity; and ubiquitin ligase-substrate adaptor activity. Involved in several processes, including cellular protein metabolic process; mitochondrion organization; and negative regulation of hydrogen peroxide-induced neuron death. Localizes to several cellular components, including Lewy body core; Lewy body corona; and Lewy neurite. Implicated in Parkinson's disease and Parkinson's disease 15.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686B08113; F-box only protein 7; FBX; FBX07; FBX7; PARK15; PKPS
Mus musculus (house mouse) : Fbxo7 (F-box protein 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbxo7 (F-box protein 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo7 (F-box protein 7)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO7 (F-box protein 7)
Canis lupus familiaris (dog) : FBXO7 (F-box protein 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo7 (F-box protein 7)
Sus scrofa (pig) : FBXO7 (F-box protein 7)
Chlorocebus sabaeus (African green monkey) : FBXO7 (F-box protein 7)
Heterocephalus glaber (naked mole-rat) : Fbxo7 (F-box protein 7)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2232,474,676 - 32,498,829 (+)EnsemblGRCh38hg38GRCh38
GRCh382232,474,682 - 32,498,831 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372232,870,707 - 32,894,818 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362231,200,707 - 31,224,818 (+)NCBINCBI36hg18NCBI36
Build 342231,195,263 - 31,219,369NCBI
Celera2216,672,879 - 16,696,990 (+)NCBI
Cytogenetic Map22q12.3NCBI
HuRef2215,827,931 - 15,852,000 (+)NCBIHuRef
CHM1_12232,830,063 - 32,854,178 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on FBXO7
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313800
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.