Dph6 (diphthamine biosynthesis 6) - Rat Genome Database

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Gene: Dph6 (diphthamine biosynthesis 6) Mus musculus
Analyze
Symbol: Dph6
Name: diphthamine biosynthesis 6
RGD ID: 1320659
MGI Page MGI
Description: Predicted to enable diphthine-ammonia ligase activity. Predicted to be involved in protein histidyl modification to diphthamide. Orthologous to human DPH6 (diphthamine biosynthesis 6).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 5730421E18Rik; ATP binding domain 4; ATP-binding domain-containing protein 4; Atpb; Atpbd4; diphthamide synthase; diphthamide synthetase; diphthine--ammonia ligase; protein DPH6 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392114,346,897 - 114,485,518 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2114,346,897 - 114,485,445 (-)EnsemblGRCm39 Ensembl
GRCm382114,516,416 - 114,655,046 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2114,516,416 - 114,654,964 (-)EnsemblGRCm38mm10GRCm38
MGSCv372114,342,154 - 114,480,664 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362114,207,859 - 114,346,369 (-)NCBIMGSCv36mm8
Celera2115,641,036 - 115,775,887 (-)NCBICelera
Cytogenetic Map2E4NCBI
cM Map257.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal coat/hair pigmentation  (IEA)
decreased body length  (IEA)
decreased CD8-positive, alpha-beta T cell number  (IEA)
decreased CD8-positive, naive alpha-beta T cell number  (IEA)
decreased effector memory CD8-positive, alpha-beta T cell number  (IEA)
decreased erythrocyte cell number  (IEA)
decreased hematocrit  (IEA)
decreased hemoglobin content  (IEA)
decreased Ly6C-positive mature NK cell number  (IEA)
decreased mature B cell number  (IEA)
decreased NK T cell number  (IEA)
decreased T-helper cell number  (IEA)
increased blood urea nitrogen level  (IEA)
increased CD11b-low dendritic cell number  (IEA)
increased CD4-positive, alpha-beta memory T cell number  (IEA)
increased CD4-positive, alpha-beta T cell number  (IEA)
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number  (IEA)
increased CD5-positive gamma-delta T cell number  (IEA)
increased circulating creatinine level  (IEA)
increased circulating magnesium level  (IEA)
increased dendritic cell number  (IEA)
increased effector memory T-helper cell number  (IEA)
increased gamma-delta T cell number  (IEA)
increased granulocyte number  (IEA)
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number  (IEA)
increased KLRG1-positive T-helper cell number  (IEA)
increased marginal zone B cell number  (IEA)
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number  (IEA)
increased memory-marker CD4-negative NK T cell number  (IEA)
increased memory-marker gamma-delta T cell number  (IEA)
increased monocyte cell number  (IEA)
increased plasma cell number  (IEA)
increased plasmacytoid dendritic cell number  (IEA)
increased red blood cell distribution width  (IEA)
vertebral transformation  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073   PMID:18799693   PMID:21267068  
PMID:21677750   PMID:21873635   PMID:23169644   PMID:29111324   PMID:30973865   PMID:32245826   PMID:38355793  


Genomics

Comparative Map Data
Dph6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392114,346,897 - 114,485,518 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2114,346,897 - 114,485,445 (-)EnsemblGRCm39 Ensembl
GRCm382114,516,416 - 114,655,046 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2114,516,416 - 114,654,964 (-)EnsemblGRCm38mm10GRCm38
MGSCv372114,342,154 - 114,480,664 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362114,207,859 - 114,346,369 (-)NCBIMGSCv36mm8
Celera2115,641,036 - 115,775,887 (-)NCBICelera
Cytogenetic Map2E4NCBI
cM Map257.74NCBI
DPH6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381535,144,977 - 35,546,165 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1535,217,345 - 35,546,193 (-)EnsemblGRCh38hg38GRCh38
GRCh371535,663,081 - 35,838,366 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361533,450,375 - 33,625,656 (-)NCBINCBI36Build 36hg18NCBI36
Celera1512,422,457 - 12,597,717 (-)NCBICelera
Cytogenetic Map15q14NCBI
HuRef1512,508,418 - 12,683,435 (-)NCBIHuRef
CHM1_11535,781,103 - 35,956,346 (-)NCBICHM1_1
T2T-CHM13v2.01532,950,308 - 33,351,518 (-)NCBIT2T-CHM13v2.0
Dph6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83121,761,495 - 121,891,727 (-)NCBIGRCr8
GRCr8 Ensembl3121,676,141 - 121,891,658 (-)EnsemblGRCr8 Ensembl
mRatBN7.23101,307,229 - 101,437,463 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3101,307,231 - 101,534,603 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3104,953,722 - 105,084,612 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03113,552,760 - 113,683,650 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03111,229,816 - 111,359,981 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03106,007,721 - 106,136,662 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3106,009,356 - 106,136,615 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03112,579,626 - 112,708,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43100,397,745 - 100,536,300 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3100,276,488 - 100,405,912 (-)NCBICelera
RGSC_v3.13100,294,173 - 100,432,728 (-)NCBI
Cytogenetic Map3q35NCBI
Dph6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554162,701,724 - 2,859,802 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554162,701,724 - 2,860,330 (-)NCBIChiLan1.0ChiLan1.0
DPH6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21624,382,251 - 24,768,176 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11528,747,480 - 28,923,028 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01514,293,746 - 14,469,331 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11532,554,276 - 32,729,455 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1532,554,276 - 32,729,455 (-)Ensemblpanpan1.1panPan2
DPH6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1303,000,723 - 3,146,568 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl302,980,437 - 3,146,568 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha303,000,875 - 3,196,175 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0303,066,202 - 3,261,206 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl303,113,310 - 3,261,963 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1302,999,857 - 3,195,107 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0303,099,636 - 3,295,078 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0303,228,666 - 3,423,950 (-)NCBIUU_Cfam_GSD_1.0
Dph6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864081,587,425 - 81,751,027 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936673400,722 - 567,184 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936673400,871 - 564,413 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPH6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1135,577,936 - 135,751,890 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11135,577,558 - 136,022,910 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21151,760,712 - 151,814,871 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DPH6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12647,360,989 - 47,799,830 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2647,361,674 - 47,539,119 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604893,111,378 - 93,560,397 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dph6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248042,563,712 - 2,783,551 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248042,565,130 - 2,783,641 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dph6
5969 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:2157
Count of miRNA genes:479
Interacting mature miRNAs:561
Transcripts:ENSMUST00000028640, ENSMUST00000055144, ENSMUST00000102542, ENSMUST00000138106, ENSMUST00000138975, ENSMUST00000150447
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292778465126778607Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1300798Actre3_mactivity response to ethanol 3 (mouse)Not determined2112024987128173821Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
15092054Egrme5_mearly growth rate, maternal effect 5 (mouse)282190187118004745Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88143423122143570Mouse
1301415Actre4_mactivity response to ethanol 4 (mouse)Not determined2112024987128173821Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286095716120095823Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286095716120095823Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287440643121440778Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103095716129213005Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284008488118008593Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286095716120095823Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined280895334114895334Mouse
10449390Actre14_mactivity response to ethanol 14 (mouse)2114123370117943090Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286095716120095823Mouse
1301098Cd8mts3_mCD8 memory T cell subset 3 (mouse)Not determined291089974125090104Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse

Markers in Region
01.MMHAP26FRA7.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382114,526,549 - 114,526,702UniSTSGRCm38
MGSCv372114,352,285 - 114,352,438UniSTSGRCm37
Cytogenetic Map2E5UniSTS
Whitehead_YAC2 UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001356438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001356439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_025675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006500019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004940694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_866334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK006965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK017595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL732404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000028640   ⟹   ENSMUSP00000028640
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2114,346,897 - 114,485,434 (-)Ensembl
GRCm38.p6 Ensembl2114,516,416 - 114,654,953 (-)Ensembl
Ensembl Acc Id: ENSMUST00000055144   ⟹   ENSMUSP00000060730
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2114,347,125 - 114,485,368 (-)Ensembl
GRCm38.p6 Ensembl2114,516,644 - 114,654,887 (-)Ensembl
Ensembl Acc Id: ENSMUST00000102542   ⟹   ENSMUSP00000099601
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2114,346,901 - 114,485,445 (-)Ensembl
GRCm38.p6 Ensembl2114,516,420 - 114,654,964 (-)Ensembl
Ensembl Acc Id: ENSMUST00000138106
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2114,348,626 - 114,376,372 (-)Ensembl
GRCm38.p6 Ensembl2114,518,145 - 114,545,891 (-)Ensembl
Ensembl Acc Id: ENSMUST00000138975
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2114,472,556 - 114,485,386 (-)Ensembl
GRCm38.p6 Ensembl2114,642,075 - 114,654,905 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150447
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2114,351,708 - 114,485,445 (-)Ensembl
GRCm38.p6 Ensembl2114,521,227 - 114,654,964 (-)Ensembl
RefSeq Acc Id: NM_001356438   ⟹   NP_001343367
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392114,346,899 - 114,485,445 (-)NCBI
GRCm382114,516,418 - 114,654,964 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001356439   ⟹   NP_001343368
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392114,346,899 - 114,485,445 (-)NCBI
GRCm382114,516,418 - 114,654,964 (-)NCBI
Sequence:
RefSeq Acc Id: NM_025675   ⟹   NP_079951
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392114,346,899 - 114,485,445 (-)NCBI
GRCm382114,516,418 - 114,654,964 (-)NCBI
MGSCv372114,342,154 - 114,480,664 (-)RGD
Celera2115,641,036 - 115,775,887 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006500019   ⟹   XP_006500082
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392114,401,474 - 114,485,518 (-)NCBI
GRCm382114,575,581 - 114,655,046 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162463   ⟹   XP_036018356
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392114,455,236 - 114,485,497 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004940694
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392114,346,897 - 114,485,513 (-)NCBI
Sequence:
RefSeq Acc Id: XR_866334
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392114,346,897 - 114,485,513 (-)NCBI
GRCm382114,516,416 - 114,655,044 (-)NCBI
Sequence:
RefSeq Acc Id: NP_079951   ⟸   NM_025675
- Peptide Label: isoform 2
- UniProtKB: Q3UL00 (UniProtKB/Swiss-Prot),   Q8R1W5 (UniProtKB/Swiss-Prot),   Q9CQ28 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006500082   ⟸   XM_006500019
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001343368   ⟸   NM_001356439
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001343367   ⟸   NM_001356438
- Peptide Label: isoform 1
Ensembl Acc Id: ENSMUSP00000028640   ⟸   ENSMUST00000028640
Ensembl Acc Id: ENSMUSP00000060730   ⟸   ENSMUST00000055144
Ensembl Acc Id: ENSMUSP00000099601   ⟸   ENSMUST00000102542
RefSeq Acc Id: XP_036018356   ⟸   XM_036162463
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CQ28-F1-model_v2 AlphaFold Q9CQ28 1-267 view protein structure

Promoters
RGD ID:6830850
Promoter ID:MM_KWN:31106
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:OTTMUST00000035192,   OTTMUST00000036054,   OTTMUST00000036055,   OTTMUST00000036056,   UC008LQN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362114,480,461 - 114,480,961 (-)MPROMDB
RGD ID:6878250
Promoter ID:EPDNEW_M2576
Type:initiation region
Name:Dph6_1
Description:Mus musculus diphthamine biosynthesis 6 , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382114,654,928 - 114,654,988EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913882 AgrOrtholog
Ensembl Genes ENSMUSG00000057147 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000028640 ENTREZGENE
  ENSMUST00000028640.14 UniProtKB/Swiss-Prot
  ENSMUST00000055144 ENTREZGENE
  ENSMUST00000055144.8 UniProtKB/Swiss-Prot
  ENSMUST00000102542 ENTREZGENE
  ENSMUST00000102542.10 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.620 UniProtKB/Swiss-Prot
  putative n-type atp pyrophosphatase, domain 2 UniProtKB/Swiss-Prot
InterPro Diphthami_syn_dom UniProtKB/Swiss-Prot
  DPH6/MJ0570 UniProtKB/Swiss-Prot
  Rossmann-like_a/b/a_fold UniProtKB/Swiss-Prot
KEGG Report mmu:66632 UniProtKB/Swiss-Prot
MGD MGI:1913882 ENTREZGENE
NCBI Gene 66632 ENTREZGENE
PANTHER DIPHTHINE--AMMONIA LIGASE UniProtKB/Swiss-Prot
  PTHR12196 UniProtKB/Swiss-Prot
Pfam Diphthami_syn_2 UniProtKB/Swiss-Prot
PhenoGen Dph6 PhenoGen
PIRSF Diphthamide_synthase UniProtKB/Swiss-Prot
Superfamily-SCOP Adenine nucleotide alpha hydrolases-like UniProtKB/Swiss-Prot
UniProt DPH6_MOUSE UniProtKB/Swiss-Prot
  Q3UL00 ENTREZGENE
  Q8R1W5 ENTREZGENE
  Q9CQ28 ENTREZGENE
UniProt Secondary Q3UL00 UniProtKB/Swiss-Prot
  Q8R1W5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-07-02 Dph6  diphthamine biosynthesis 6  Atpbd4  ATP binding domain 4  Symbol and/or name change 5135510 APPROVED