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Gene: Tcf12 (transcription factor 12) Mus musculus
Symbol: Tcf12
Name: transcription factor 12
Description: Exhibits E-box binding activity and protein heterodimerization activity. Predicted to contribute to transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of neuron differentiation and positive regulation of transcription, DNA-templated. Localizes to transcription regulator complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in craniosynostosis. Orthologous to human TCF12 (transcription factor 12); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroperoxycyclophosphamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A130037E08Rik; ALF1; bHLHb20; class A helix-loop-helix transcription factor ME1; DNA-binding protein HTF4; E-box-binding protein; HEB; HEBAlt; HTF-4; HTF4; ME1; REB; RIKEN cDNA A130037E08 gene; TCF-12; transcription factor HTF-4
Homo sapiens (human) : TCF12 (transcription factor 12)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tcf12 (transcription factor 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tcf12 (transcription factor 12)
Pan paniscus (bonobo/pygmy chimpanzee) : TCF12 (transcription factor 12)
Canis lupus familiaris (dog) : TCF12 (transcription factor 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tcf12 (transcription factor 12)
Sus scrofa (pig) : TCF12 (transcription factor 12)
Chlorocebus sabaeus (African green monkey) : TCF12 (transcription factor 12)
Heterocephalus glaber (naked mole-rat) : Tcf12 (transcription factor 12)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl971,842,688 - 72,111,871 (-)EnsemblGRCm38mm10GRCm38
GRCm38971,844,252 - 72,111,893 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37971,692,059 - 71,959,626 (-)NCBIGRCm37mm9NCBIm37
MGSCv36971,644,313 - 71,910,179 (-)NCBImm8
Celera969,039,252 - 69,300,279 (-)NCBICelera
Cytogenetic Map9DNCBI
cM Map939.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Tcf12
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731956
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.