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Gene: Stk4 (serine/threonine kinase 4) Mus musculus
Symbol: Stk4
Name: serine/threonine kinase 4
Description: Predicted to have several functions, including ATP binding activity; magnesium ion binding activity; and protein homodimerization activity. Involved in several processes, including animal organ development; epithelial tube morphogenesis; and regulation of signal transduction. Localizes to the cytoplasm and nucleus. Is expressed in ovary; renal vasculature; and testis. Orthologous to human STK4 (serine/threonine kinase 4); PARTICIPATES IN mitogen activated protein kinase signaling pathway; non-small cell lung carcinoma pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; alendronic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI447339; AU020804; Kas-2; mammalian STE20-like protein kinase 1; MST-1; Mst1; serine/threonine-protein kinase 4; Sps1/Ste20-related kinase 3; STE20-like kinase MST1; sterile 20-like kinase 1; Yeast Sps1/Ste20-related kinase 3; Ysk3
Homo sapiens (human) : STK4 (serine/threonine kinase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Stk4 (serine/threonine kinase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stk4 (serine/threonine kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : STK4 (serine/threonine kinase 4)
Canis lupus familiaris (dog) : STK4 (serine/threonine kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stk4 (serine/threonine kinase 4)
Sus scrofa (pig) : STK4 (serine/threonine kinase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382164,074,113 - 164,155,524 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372163,899,914 - 163,981,257 (+)NCBIGRCm37mm9NCBIm37
MGSCv362163,765,619 - 163,846,962 (+)NCBImm8
Celera2170,004,346 - 170,087,071 (+)NCBICelera
Cytogenetic Map2 H3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Stk4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323809
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.