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Gene: Stk4 (serine/threonine kinase 4) Mus musculus
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Symbol: Stk4
Name: serine/threonine kinase 4
Description: Predicted to have several functions, including ATP binding activity; magnesium ion binding activity; and protein homodimerization activity. Involved in several processes, including animal organ development; epithelial tube morphogenesis; and regulation of signal transduction. Localizes to the cytoplasm and nucleus. Is expressed in ovary; renal vasculature; and testis. Orthologous to human STK4 (serine/threonine kinase 4); PARTICIPATES IN mitogen activated protein kinase signaling pathway; non-small cell lung carcinoma pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; alendronic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI447339; AU020804; Kas-2; mammalian STE20-like protein kinase 1; MST-1; Mst1; serine/threonine-protein kinase 4; Sps1/Ste20-related kinase 3; STE20-like kinase MST1; sterile 20-like kinase 1; Yeast Sps1/Ste20-related kinase 3; Ysk3
Orthologs:
Homo sapiens (human) : STK4 (serine/threonine kinase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Stk4 (serine/threonine kinase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stk4 (serine/threonine kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : STK4 (serine/threonine kinase 4)
Canis lupus familiaris (dog) : STK4 (serine/threonine kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stk4 (serine/threonine kinase 4)
Sus scrofa (pig) : STK4 (serine/threonine kinase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382164,074,113 - 164,155,524 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372163,899,914 - 163,981,257 (+)NCBIGRCm37mm9NCBIm37
MGSCv362163,765,619 - 163,846,962 (+)NCBImm8
Celera2170,004,346 - 170,087,071 (+)NCBICelera
Cytogenetic Map2 H3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Stk4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323809
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.