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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular biogenic amine biosynthetic process
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Accession:GO:0042401 term browser browse the term
Definition:The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
Synonyms:exact_synonym: biogenic amine anabolism;   biogenic amine biosynthesis;   biogenic amine formation;   biogenic amine synthesis


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histamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdc histidine decarboxylase IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
(PMID:22767596)
GO_REF:0000107
MGI:MGI:2182618 (MGI:MGI:2138019|PMID:11478947)
UniProt
RGD
Ensembl
PMID:11478947, PMID:22767596, PMID:21873635 GO_REF:0000041, GO_REF:0000107, MGI:MGI:2138019, RGD:13792537 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 ISO (PMID:10318872) RGD PMID:10318872 NCBI chr 3:72,395,194...72,401,254
Ensembl chr 3:72,395,218...72,401,318
JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:22,124,498...22,206,565
Ensembl chr 1:22,124,495...22,206,505
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398
JBrowse link
G Azin2 antizyme inhibitor 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:147,120,128...147,148,576
Ensembl chr 5:147,120,129...147,148,291
JBrowse link
G LOC100912604 spermidine synthase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,588,818...14,591,980
Ensembl chr 3:14,588,870...14,591,974
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:11,752,127...11,754,587
Ensembl chr 7:11,752,412...11,754,508
JBrowse link
G Odc1 ornithine decarboxylase 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 ISO (PMID:15283699) RGD PMID:15283699 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 NOT ISO (PMID:15283699) RGD PMID:15283699 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
G Srm spermidine synthase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
positive regulation of spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase ISO (PMID:16354669) RGD PMID:16354669 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
putrescine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Odc1 ornithine decarboxylase 1 IDA RGD PMID:10430362, PMID:1415709 RGD:1578320, RGD:7242912 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Paox polyamine oxidase ISO (PMID:16354669) RGD PMID:16354669 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
putrescine biosynthetic process from arginine, using agmatinase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:160,306,754...160,321,951
Ensembl chr 5:160,306,727...160,321,066
JBrowse link
putrescine biosynthetic process from ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398
JBrowse link
G Azin2 antizyme inhibitor 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:147,120,128...147,148,576
Ensembl chr 5:147,120,129...147,148,291
JBrowse link
G Odc1 ornithine decarboxylase 1 IEA
IBA
ISS
ISO
GO_REF:0000041
PMID:21873635
GO_REF:0000024
(MGI:MGI:5574513|PMID:24967154)
UniProt
RGD
PMID:24967154, PMID:21873635 GO_REF:0000024, GO_REF:0000041, MGI:MGI:5574513, RGD:13792537 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G RGD1562036 similar to ornithine decarboxylase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:148,432,213...148,444,188
Ensembl chr 5:148,433,086...148,444,188
JBrowse link
spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:160,306,754...160,321,951
Ensembl chr 5:160,306,727...160,321,066
JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 IDA
ISO
IBA
IMP
(MGI:MGI:3584197|PMID:11856372)
PMID:21873635
RGD PMID:11856372, PMID:10430362, PMID:21873635, PMID:1415709, PMID:10712236 MGI:MGI:3584197, RGD:1578320, RGD:13792537, RGD:7242912, RGD:7242911 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694
JBrowse link
G LOC100912604 spermidine synthase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,588,818...14,591,980
Ensembl chr 3:14,588,870...14,591,974
JBrowse link
G Srm spermidine synthase IDA
IBA
ISO
IMP
PMID:21873635
(PMID:17585781)
RGD PMID:17585781, PMID:12843627, PMID:21873635, PMID:8494549, PMID:16931179 RGD:1359042, RGD:13792537, RGD:7242928, RGD:7242920 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA
ISO
IBA
IMP
(MGI:MGI:3584197|PMID:11856372)
PMID:21873635
RGD PMID:11856372, PMID:10430362, PMID:21873635, PMID:1415709, PMID:10712236 MGI:MGI:3584197, RGD:1578320, RGD:13792537, RGD:7242912, RGD:7242911 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694
JBrowse link
G Sms spermine synthase IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:8494549, PMID:21873635 RGD:7242928, RGD:13792537 NCBI chr  X:40,363,646...40,415,110
Ensembl chr  X:40,363,646...40,415,109
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      cellular metabolic process 11085
        cellular nitrogen compound metabolic process 6696
          cellular nitrogen compound biosynthetic process 5067
            amine biosynthetic process 18
              cellular biogenic amine biosynthetic process 18
                choline biosynthetic process + 0
                ethanolamine biosynthetic process 0
                histamine biosynthetic process 2
                indolalkylamine biosynthetic process + 0
                nicotianamine biosynthetic process 0
                octopamine biosynthetic process 3
                phenylethylamine biosynthetic process + 0
                polyamine biosynthetic process + 13
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        organonitrogen compound metabolic process 7186
          amine metabolic process 93
            cellular amine metabolic process 85
              cellular biogenic amine metabolic process 48
                cellular biogenic amine biosynthetic process 18
                  choline biosynthetic process + 0
                  ethanolamine biosynthetic process 0
                  histamine biosynthetic process 2
                  indolalkylamine biosynthetic process + 0
                  nicotianamine biosynthetic process 0
                  octopamine biosynthetic process 3
                  phenylethylamine biosynthetic process + 0
                  polyamine biosynthetic process + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.