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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular biogenic amine metabolic process
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Accession:GO:0006576 term browser browse the term
Definition:The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
Synonyms:exact_synonym: biogenic amine metabolism


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cellular biogenic amine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mecp2 methyl CpG binding protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2137311 (MGI:3607765|PMID:15975715)
Ensembl
RGD
PMID:15975715 GO_REF:0000107 MGI:3607765 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
catecholamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:17194738 RGD:5131263 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
JBrowse link
G Ddc dopa decarboxylase involved_in TAS
IEA
GO_REF:0000043 UniProt PMID:12047348 GO_REF:0000043, RGD:727571 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Hdc histidine decarboxylase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Th tyrosine hydroxylase IDA RGD PMID:20025246 RGD:4139888 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
catecholamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:11559542), (PMID:15645182), (PMID:21846718)
UniProt
RGD
PMID:11559542 PMID:15645182 PMID:21846718 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:3799635|PMID:18794526)
PMID:21873635
UniProt
RGD
PMID:18794526 PMID:21873635 GO_REF:0000024 MGI:3799635, RGD:13792537 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704
JBrowse link
G Maoa monoamine oxidase A NAS RGD PMID:12388421 RGD:629546 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098 (MGI:54307|PMID:17511) RGD PMID:17511 MGI:54307 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Dbh dopamine beta-hydroxylase IC RGD PMID:11521740 RGD:1625401 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Ddc dopa decarboxylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Mtpn myotrophin IEP RGD PMID:12051753 RGD:625450 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 IDA RGD PMID:6959650 RGD:2301075 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1d1 sulfotransferase family 1D, member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:20,441,135...20,476,341
Ensembl chr14:20,441,924...20,476,341
JBrowse link
choline catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase involved_in TAS
ISO
IEA
(PMID:10102904)
GO_REF:0000107
RGD
Ensembl
PMID:10102904 PMID:1710985 GO_REF:0000107, RGD:632576 NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528
JBrowse link
G Sardh sarcosine dehydrogenase involved_in TAS
NAS
PMID:9839943 RGD
UniProt
PMID:9839943 PMID:9839943 RGD:634034, RGD:634034 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874
JBrowse link
dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:20097214 RGD:6903884 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:20097214 RGD:6903884 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit IEP RGD PMID:12438507 RGD:704388 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:19818757 RGD:5143981 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Dao D-amino-acid oxidase involved_in ISO
IEA
(PMID:17303072)
GO_REF:0000107
RGD
Ensembl
PMID:17303072 GO_REF:0000107 NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741
JBrowse link
G Ddc dopa decarboxylase involved_in IDA
IEA
GO_REF:0000041 UniProt PMID:12703659 GO_REF:0000041, RGD:4139893 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:16338639) RGD PMID:16338639 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gpr37 G protein-coupled receptor 37 acts_upstream_of_or_within ISO MGI:3027995 (MGI:3046856|PMID:15218106) RGD PMID:15218106 MGI:3046856 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2429971 (MGI:1203924|PMID:9608532), (MGI:3767764|PMID:16782508)
Ensembl
RGD
PMID:9608532 PMID:16782508 GO_REF:0000107 MGI:1203924 MGI:3767764 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:1888382 (MGI:1352916|PMID:10707987) RGD PMID:10707987 MGI:1352916 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3622848|PMID:16257223)
UniProt
RGD
PMID:16257223 GO_REF:0000024 MGI:3622848 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Th tyrosine hydroxylase involved_in ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase acts_upstream_of_or_within
involved_in
IDA
ISO
IMP
IBA
MGI:1860450 (MGI:2386819|PMID:9520487), (MGI:72094|PMID:7715703), (MGI:77787|PMID:7592982)
PMID:11943812
PMID:21873635
RGD PMID:7592982 PMID:7715703 PMID:9520487 PMID:2427363 PMID:11943812 More... MGI:2386819 MGI:72094 MGI:77787, RGD:1580046, RGD:5129111, RGD:13792537, RGD:5130972 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
dopamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
ISS
(PMID:3443096), (PMID:7961964)
(MGI:5787847|PMID:27148966), (MGI:72180|PMID:7715704)
MGI:1857556 (MGI:1332340|PMID:10051631)
PMID:21873635
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:3443096 PMID:7715704 PMID:7961964 PMID:10051631 PMID:27148966 More... GO_REF:0000024 GO_REF:0000107 MGI:1332340 MGI:5787847 MGI:72180, RGD:13792537 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Maoa monoamine oxidase A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2386819|PMID:9520487)
Ensembl
RGD
PMID:9520487 GO_REF:0000107 MGI:2386819 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299
JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098|MGI:1856466 (MGI:50550|PMID:1752214), (MGI:65000|PMID:8174230) RGD PMID:1752214 PMID:8174230 MGI:50550 MGI:65000 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Comt catechol-O-methyltransferase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5510279|PMID:23863468)
MGI:2178542|MGI:4830700 (MGI:4830461|PMID:19930170)
RGD PMID:19930170 PMID:23863468 PMID:21873635 MGI:4830461 MGI:5510279, RGD:13792537 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:10945868 RGD:1599723 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Ddc dopa decarboxylase TAS RGD PMID:7567987 RGD:727686 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO (MGI:68905|PMID:7925842) RGD PMID:7925842 MGI:68905 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1928285 (MGI:2384280|PMID:11160454)
Ensembl
RGD
PMID:11160454 GO_REF:0000107 MGI:2384280 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 acts_upstream_of_or_within ISO MGI:1857299 (MGI:1321418|PMID:9886073), (MGI:65825|PMID:7509865), (MGI:65928|PMID:1432691) RGD PMID:1432691 PMID:7509865 PMID:9886073 MGI:1321418 MGI:65825 MGI:65928 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704
JBrowse link
G Myo5a myosin VA IMP RGD PMID:29217155 RGD:42721980 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 acts_upstream_of_or_within ISO MGI:3527173 (MGI:6150107|PMID:28327638) RGD PMID:28327638 MGI:6150107 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
JBrowse link
G Npr1 natriuretic peptide receptor 1 IMP RGD PMID:15544851 RGD:1580153 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 acts_upstream_of_or_within ISO MGI:2429971 (MGI:3529728|PMID:12385813) RGD PMID:12385813 MGI:3529728 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within
NOT|acts_upstream_of_or_within
ISO MGI:2678247 (MGI:2675710|PMID:12915482)
MGI:3055212 (MGI:3525458|PMID:15684050)
RGD PMID:12915482 PMID:15684050 MGI:2675710 MGI:3525458 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (MGI:5904876|PMID:28507136) RGD PMID:28507136 MGI:5904876 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:1889011 (MGI:3057254|PMID:15465911) RGD PMID:15465911 MGI:3057254 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sncaip synuclein, alpha interacting protein involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:14506261)
ParkinsonsUK-UCL
RGD
PMID:14506261 GO_REF:0000024 NCBI chr18:46,205,846...46,343,932
Ensembl chr18:46,207,152...46,343,929
JBrowse link
G Sncb synuclein, beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1277151 (MGI:3057254|PMID:15465911)
Ensembl
RGD
PMID:15465911 GO_REF:0000107 MGI:3057254 NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012
JBrowse link
G Spr sepiapterin reductase acts_upstream_of_or_within ISO MGI:3757641 (MGI:3722569|PMID:16532389) RGD PMID:16532389 MGI:3722569 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678
JBrowse link
epinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnmt phenylethanolamine-N-methyltransferase involved_in TAS
IEA
IDA
IC
GO_REF:0000041 UniProt PMID:11514309 PMID:7914070 PMID:7503429 GO_REF:0000041, RGD:628457, RGD:4139902, RGD:4139901 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556
JBrowse link
G Th tyrosine hydroxylase involved_in ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
epinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098|MGI:1856466 (MGI:50550|PMID:1752214) RGD PMID:1752214 MGI:50550 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
ethanolamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chka choline kinase alpha IDA RGD PMID:1577786 RGD:61551 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3793397|PMID:18227059)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:18227059 GO_REF:0000024 GO_REF:0000107 MGI:3793397 NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429
JBrowse link
histamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdc histidine decarboxylase involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
MGI:2182618 (MGI:2138019|PMID:11478947)
GO_REF:0000107
GO_REF:0000041
(PMID:22767596)
RGD
Ensembl
UniProt
PMID:11478947 PMID:22767596 PMID:21873635 GO_REF:0000041 GO_REF:0000107 MGI:2138019, RGD:13792537 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 involved_in ISO (PMID:10318872) RGD PMID:10318872 NCBI chr 3:70,071,970...70,078,103
Ensembl chr 3:70,072,497...70,078,102
JBrowse link
histamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase involved_in ISO
ISS
(PMID:26206890)
GO_REF:0000024
RGD
UniProt
PMID:26206890 GO_REF:0000024 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
histamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdc histidine decarboxylase IDA RGD PMID:4449071 PMID:9525922 PMID:7075603 PMID:5898 RGD:2303726, RGD:2303735, RGD:2303728, RGD:2303727 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hnmt histamine N-methyltransferase involved_in ISO (PMID:23505051) RGD PMID:23505051 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
G Trh thyrotropin releasing hormone involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:17760865 PMID:21873635 RGD:7241067, RGD:13792537 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
JBrowse link
N-acylethanolamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B acts_upstream_of_or_within ISO (MGI:3695251|PMID:16818490) RGD PMID:16818490 MGI:3695251 NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
(MGI:5295534|PMID:21801852)
(MGI:5790171|PMID:25596343)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21801852 PMID:25596343 GO_REF:0000024 GO_REF:0000107 MGI:5295534 MGI:5790171 NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429
JBrowse link
G Gdpd1 glycerophosphodiester phosphodiesterase domain containing 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
IEA
GO_REF:0000024
(PMID:25596343)
(PMID:27637550)
(MGI:6104349|PMID:27637550)
(MGI:5790171|PMID:25596343)
PMID:21873635
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:25596343 PMID:27637550 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5790171 MGI:6104349, RGD:13792537 NCBI chr10:71,840,497...71,883,936
Ensembl chr10:71,840,497...71,883,850
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 involved_in ISO (PMID:27637550)
(MGI:6104349|PMID:27637550)
RGD PMID:27637550 MGI:6104349 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063
JBrowse link
G Naaa N-acylethanolamine acid amidase involved_in IDA
ISS
ISO
PMID:22860206
GO_REF:0000024
(PMID:15655246), (PMID:30301806)
UniProt
RGD
PMID:15655246 PMID:30301806 PMID:22860206 GO_REF:0000024, RGD:39458030 NCBI chr14:15,777,306...15,796,411
Ensembl chr14:15,777,306...15,796,410
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3695401 (MGI:3044670|PMID:14634025), (MGI:3695251|PMID:16818490)
RGD PMID:14634025 PMID:16818490 PMID:21873635 MGI:3044670 MGI:3695251, RGD:13792537 NCBI chr 4:13,360,532...13,398,815
Ensembl chr 4:13,361,006...13,398,748
JBrowse link
negative regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098 (MGI:54307|PMID:17511) RGD PMID:17511 MGI:54307 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
negative regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IMP RGD PMID:15190105 RGD:2289786 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:17018023 RGD:1625003 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (MGI:3814938|PMID:18981141) RGD PMID:18981141 MGI:3814938 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Snca synuclein alpha involved_in IMP PMID:11943812 BHF-UCL PMID:11943812 RGD:5129111 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
nor-spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 involved_in ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856097|MGI:1856098 (MGI:53801|PMID:4405722), (MGI:53940|PMID:4858102) RGD PMID:4405722 PMID:4858102 MGI:53801 MGI:53940 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within
TAS
ISO
ISS
IBA
IEA
IMP
(MGI:5787847|PMID:27148966), (MGI:72180|PMID:7715704)
MGI:1857556 (MGI:1203930|PMID:9603211), (MGI:1332340|PMID:10051631)
(PMID:27148966)
GO_REF:0000024
PMID:21873635
GO_REF:0000041
RGD
UniProt
PMID:7715704 PMID:9603211 PMID:10051631 PMID:27148966 PMID:11914591 More... GO_REF:0000024 GO_REF:0000041 MGI:1203930 MGI:1332340 MGI:5787847 MGI:72180, RGD:727567, RGD:13792537, RGD:1625403 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Gata3 GATA binding protein 3 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2153826 (MGI:1859081|PMID:10835639)
UniProt
RGD
PMID:10835639 GO_REF:0000024 MGI:1859081 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Insm1 INSM transcriptional repressor 1 involved_in ISO (MGI:3772428|PMID:18094025) RGD PMID:18094025 MGI:3772428 NCBI chr 3:133,639,790...133,642,963 JBrowse link
G Kl Klotho IMP RGD PMID:20086041 RGD:10403068 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299
JBrowse link
G Th tyrosine hydroxylase involved_in ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
norepinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B IDA RGD PMID:10424772 RGD:8548769 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856102|MGI:1856466 (MGI:53851|PMID:4147174) RGD PMID:4147174 MGI:53851 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Ednra endothelin receptor type A involved_in ISO MGI:2687362 (MGI:5608725|PMID:25197047) RGD PMID:25197047 MGI:5608725 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Epas1 endothelial PAS domain protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1861921 (MGI:1313089|PMID:9808618)
Ensembl
RGD
PMID:9808618 GO_REF:0000107 MGI:1313089 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Ly6e lymphocyte antigen 6 family member E acts_upstream_of_or_within ISO MGI:2429638 (MGI:2157257|PMID:11784869) RGD PMID:11784869 MGI:2157257 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IDA RGD PMID:3945626 RGD:5130757 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3050230 (MGI:3047192|PMID:15249681) RGD PMID:15249681 MGI:3047192 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Rnf180 ring finger protein 180 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5505713|PMID:23926250)
RGD PMID:23926250 PMID:21873635 MGI:5505713, RGD:13792537 NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614
JBrowse link
G Rtl4 retrotransposon Gag like 4 acts_upstream_of_or_within ISO MGI:5789261 (MGI:5749620|PMID:26402067) RGD PMID:26402067 MGI:5749620 NCBI chr  X:108,231,052...108,641,768
Ensembl chr  X:108,633,651...108,640,050
JBrowse link
G Spr sepiapterin reductase acts_upstream_of_or_within ISO MGI:3757641 (MGI:3722569|PMID:16532389) RGD PMID:16532389 MGI:3722569 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678
JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299
JBrowse link
octopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase IMP RGD PMID:11521740 RGD:1625401 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
phenylethylamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Maoa monoamine oxidase A IDA
IMP
Y402A, Y407A, Y410A had an impact on the properties of the protein while Y402F, Y410F had little effect; the residues are near the C406 FAD binding site RGD PMID:11754741 PMID:11754741 RGD:1600709, RGD:1600709 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
JBrowse link
G Azin2 antizyme inhibitor 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:141,281,310...141,310,415
Ensembl chr 5:141,281,249...141,310,397
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310
JBrowse link
G Odc1 ornithine decarboxylase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 involved_in ISO (PMID:15283699) RGD PMID:15283699 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 NOT|involved_in ISO (PMID:15283699) RGD PMID:15283699 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
G Srm spermidine synthase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:159,025,919...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
polyamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:2663545|PMID:12660232)
(PMID:12477380)
RGD PMID:12477380 PMID:12660232 PMID:15541750 MGI:2663545, RGD:7244190 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA RGD PMID:15541750 RGD:7244190 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Smox spermine oxidase involved_in ISO (PMID:12477380) RGD PMID:12477380 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
polyamine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 involved_in ISS
ISO
GO_REF:0000024
(PMID:28516954)
UniProt
RGD
PMID:28516954 GO_REF:0000024 NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
JBrowse link
G Hdac6 histone deacetylase 6 NOT|involved_in ISO (PMID:28516954) RGD PMID:28516954 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
polyamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA RGD PMID:10430362 RGD:1578320 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Oaz2 ornithine decarboxylase antizyme 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:66,199,694...66,213,513
Ensembl chr 8:66,199,706...66,231,453
JBrowse link
G Odc1 ornithine decarboxylase 1 IDA RGD PMID:10430362 RGD:1578320 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA RGD PMID:11172929 RGD:1599544 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19703902)
ParkinsonsUK-UCL
Ensembl
RGD
PMID:19703902 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) RGD PMID:26203154 MGI:5694519 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618
JBrowse link
positive regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:11239920 RGD:10047061 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Gpr37 G protein-coupled receptor 37 acts_upstream_of_or_within ISO MGI:3027995 (MGI:3046856|PMID:15218106) RGD PMID:15218106 MGI:3046856 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO (PMID:8643611) RGD PMID:8643611 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Maob monoamine oxidase B IMP RGD PMID:12175458 RGD:2316765 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Npy neuropeptide Y IDA RGD PMID:19579268 RGD:10448966 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
positive regulation of spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase involved_in ISO (PMID:16354669) RGD PMID:16354669 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:4413411|PMID:19008477)
Ensembl
RGD
PMID:19008477 GO_REF:0000107 MGI:4413411 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891
JBrowse link
putrescine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 involved_in ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
putrescine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Odc1 ornithine decarboxylase 1 IDA RGD PMID:10430362 PMID:1415709 RGD:1578320, RGD:7242912 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Paox polyamine oxidase involved_in ISO (PMID:16354669) RGD PMID:16354669 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
putrescine biosynthetic process from arginine, using agmatinase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:154,043,665...154,074,278
Ensembl chr 5:154,060,151...154,074,276
JBrowse link
putrescine biosynthetic process from ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
JBrowse link
G Azin2 antizyme inhibitor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:141,281,310...141,310,415
Ensembl chr 5:141,281,249...141,310,397
JBrowse link
G Odc1 ornithine decarboxylase 1 involved_in ISS
ISO
IBA
IEA
GO_REF:0000024
(MGI:5574513|PMID:24967154)
PMID:21873635
GO_REF:0000041
UniProt
RGD
PMID:24967154 PMID:21873635 GO_REF:0000024 GO_REF:0000041 MGI:5574513, RGD:13792537 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G RGD1562036 similar to ornithine decarboxylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:142,551,120...142,563,217
Ensembl chr 5:142,552,008...142,563,074
JBrowse link
putrescine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase involved_in ISO
IDA
(PMID:16354669) RGD PMID:16354669 PMID:16354669 RGD:12790650 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
putrescine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aoc1 amine oxidase, copper containing 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:8144586)
UniProt
RGD
PMID:8144586 GO_REF:0000024 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
JBrowse link
regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vhl von Hippel-Lindau tumor suppressor IMP RGD PMID:11912140 RGD:619592 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377
JBrowse link
regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (MGI:3618656|PMID:11282258) RGD PMID:11282258 MGI:3618656 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857158 (MGI:2136539|PMID:11438590)
Ensembl
RGD
PMID:11438590 GO_REF:0000107 MGI:2136539 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd4 dopamine receptor D4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2178631 (MGI:1097029|PMID:9323127)
Ensembl
RGD
PMID:9323127 GO_REF:0000107 MGI:1097029 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A involved_in ISS
ISO
GO_REF:0000024
(MGI:1927024|PMID:11080193)
UniProt
RGD
PMID:11080193 GO_REF:0000024 MGI:1927024 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2671567|PMID:12915123)
Ensembl
RGD
PMID:12915123 GO_REF:0000107 MGI:2671567 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Pde1b phosphodiesterase 1B acts_upstream_of_or_within ISO MGI:3604470 (MGI:3769297|PMID:17559891) RGD PMID:17559891 MGI:3769297 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580
JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing acts_upstream_of_or_within ISO MGI:5006973 (MGI:5466578|PMID:22214848) RGD PMID:22214848 MGI:5466578 NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:22314364) RGD PMID:22314364 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (MGI:2386819|PMID:9520487), (MGI:894559|PMID:9247269) RGD PMID:9247269 PMID:9520487 MGI:2386819 MGI:894559 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:8574643 RGD:2305963 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791
JBrowse link
regulation of polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nnmt nicotinamide N-methyltransferase involved_in ISO
IEA
(MGI:5565106|PMID:24717514)
GO_REF:0000107
RGD
Ensembl
PMID:24717514 GO_REF:0000107 MGI:5565106 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:23098818 RGD:11353778 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Tph1 tryptophan hydroxylase 1 TAS RGD PMID:12153488 RGD:625621 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
JBrowse link
spermidine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyl transferase 1 involved_in IDA
IBA
ISO
PMID:21873635
(PMID:15283699)
RGD PMID:15283699 PMID:15541750 PMID:21873635 RGD:7244190, RGD:13792537 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 involved_in
NOT|involved_in
IBA
ISO
PMID:21873635
(PMID:12803540)
(PMID:15283699)
RGD PMID:12803540 PMID:15283699 PMID:21873635 RGD:13792537 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:154,043,665...154,074,278
Ensembl chr 5:154,060,151...154,074,276
JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
IMP
(MGI:3584197|PMID:11856372)
PMID:21873635
RGD PMID:11856372 PMID:10430362 PMID:21873635 PMID:1415709 PMID:10712236 MGI:3584197, RGD:1578320, RGD:13792537, RGD:7242912, RGD:7242911 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Srm spermidine synthase involved_in IDA
ISO
IBA
IMP
(PMID:17585781)
PMID:21873635
RGD PMID:17585781 PMID:12843627 PMID:21873635 PMID:8494549 PMID:16931179 RGD:1359042, RGD:13792537, RGD:7242928, RGD:7242920 NCBI chr 5:159,025,919...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
spermidine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase IDA RGD PMID:7721768 RGD:2316236 NCBI chr19:23,082,454...23,086,544
Ensembl chr19:23,082,448...23,086,881
JBrowse link
G Paox polyamine oxidase involved_in IDA
ISO
PMID:16354669
(PMID:16354669)
RGD PMID:16354669 PMID:7560898 PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
spermidine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 involved_in ISO
ISS
(PMID:28516954)
GO_REF:0000024
RGD
UniProt
PMID:28516954 GO_REF:0000024 NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
JBrowse link
G Hdac6 histone deacetylase 6 NOT|involved_in ISO (PMID:28516954) RGD PMID:28516954 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase involved_in ISO (PMID:23525104) RGD PMID:23525104 NCBI chr19:23,082,454...23,086,544
Ensembl chr19:23,082,448...23,086,881
JBrowse link
spermine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyl transferase 1 IC RGD PMID:15541750 RGD:7244190 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 involved_in ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
IMP
(MGI:3584197|PMID:11856372)
PMID:21873635
RGD PMID:11856372 PMID:10430362 PMID:21873635 PMID:1415709 PMID:10712236 MGI:3584197, RGD:1578320, RGD:13792537, RGD:7242912, RGD:7242911 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Sms spermine synthase involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:8494549 PMID:21873635 RGD:7242928, RGD:13792537 NCBI chr  X:37,516,949...37,572,657
Ensembl chr  X:37,516,931...37,570,822
JBrowse link
spermine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase involved_in IDA
ISO
PMID:16354669
(PMID:16354669)
RGD PMID:16354669 PMID:7560898 PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Smox spermine oxidase acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:2429361|PMID:12141946)
(PMID:18422650)
RGD PMID:12141946 PMID:18422650 PMID:15541750 MGI:2429361, RGD:7244190 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
spermine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sms spermine synthase acts_upstream_of_or_within ISO MGI:2180359 (MGI:1197776|PMID:9467015) RGD PMID:9467015 MGI:1197776 NCBI chr  X:37,516,949...37,572,657
Ensembl chr  X:37,516,931...37,570,822
JBrowse link
tryptophan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase IDA RGD PMID:11802786 RGD:70243 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:17356132), (PMID:25767141) RGD PMID:17356132 PMID:25767141 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Kynu kynureninase involved_in ISO (PMID:17334708) RGD PMID:17334708 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase IDA RGD PMID:7236232 RGD:2303721 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7236232 PMID:21873635 RGD:2303721, RGD:13792537 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link
tryptophan catabolic process to indole-3-acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467), (PMID:32866000) RGD PMID:32818467 PMID:32866000 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3587527|PMID:15866519)
GO_REF:0000041
RGD
UniProt
PMID:15866519 PMID:21873635 GO_REF:0000041 MGI:3587527, RGD:13792537 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within
IDA
IEA
ISO
IBA
GO_REF:0000002
(MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753)
PMID:21873635
InterPro
RGD
PMID:2419335 PMID:11751753 PMID:10719243 PMID:21873635 PMID:11513477 GO_REF:0000002 MGI:2151782 MGI:2156954, RGD:2290190, RGD:13792537, RGD:2290543 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3712725|PMID:17499941), (MGI:3719924|PMID:17671174)
(PMID:17671174)
GO_REF:0000041
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:17499941 PMID:17671174 PMID:21873635 GO_REF:0000041 GO_REF:0000107 MGI:3712725 MGI:3719924, RGD:13792537 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Kynu kynureninase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:27762317)
GO_REF:0000041
UniProt
RGD
PMID:27762317 GO_REF:0000024 GO_REF:0000041 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link
tryptophan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856102 (MGI:53851|PMID:4147174) RGD PMID:4147174 MGI:53851 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IDA RGD PMID:10719243 PMID:3899109 PMID:3400092 RGD:2290190, RGD:2291804, RGD:2290313 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      nitrogen compound metabolic process 9982
        cellular nitrogen compound metabolic process 6561
          cellular amine metabolic process 117
            cellular biogenic amine metabolic process 104
              catecholamine metabolic process + 62
              cellular biogenic amine biosynthetic process + 41
              cellular biogenic amine catabolic process + 23
              ethanolamine-containing compound metabolic process + 10
              histamine metabolic process + 4
              indolalkylamine metabolic process + 12
              nicotianamine metabolic process + 0
              phenylethylamine metabolic process + 1
              polyamine metabolic process + 19
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      organic substance metabolic process 11337
        organonitrogen compound metabolic process 6802
          amine metabolic process 125
            cellular amine metabolic process 117
              cellular biogenic amine metabolic process 104
                catecholamine metabolic process + 62
                cellular biogenic amine biosynthetic process + 41
                cellular biogenic amine catabolic process + 23
                ethanolamine-containing compound metabolic process + 10
                histamine metabolic process + 4
                indolalkylamine metabolic process + 12
                nicotianamine metabolic process + 0
                phenylethylamine metabolic process + 1
                polyamine metabolic process + 19
paths to the root