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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to estradiol stimulus
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Accession:GO:0071392 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
Synonyms:exact_synonym: cellular response to E2 stimulus


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cellular response to estradiol stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A involved_in ISO
IEA		 RGD
Ensembl		 PMID:23707492 GO_REF:0000107 RGD:8657098 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO RGD PMID:23592396 RGD:11099979 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:16776830 GO_REF:0000107 RGD:10053566 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440 		JBrowse link
G Aqp4 aquaporin 4 ISO RGD PMID:21471464 RGD:5490119 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039 		JBrowse link
G Bcl2l11 BCL2 like 11 ISO RGD PMID:17287517 RGD:14394420 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467 		JBrowse link
G Bcl2l2 BCL2-like 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:17287517 GO_REF:0000107 RGD:14394420 NCBI chr14:55,120,900...55,125,691
Ensembl chr14:55,120,834...55,125,691 		JBrowse link
G Ccdc62 coiled-coil domain containing 62 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:124,068,683...124,107,958
Ensembl chr 5:124,065,481...124,107,958 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:17237237 GO_REF:0000107 RGD:11526151 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccna2 cyclin A2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:9275057 GO_REF:0000107 RGD:10054467 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO RGD PMID:26566102 RGD:11341731 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein involved_in IDA
ISO		 (PMID:15345745) UniProt
GO_Central		 PMID:15345745 GO_REF:0000096 GO_REF:0000119 NCBI chr13:95,567,884...95,581,339
Ensembl chr13:95,567,879...95,581,432 		JBrowse link
G Ddx18 DEAD box helicase 18 ISO RGD PMID:8861962 RGD:10755358 NCBI chr 1:121,481,564...121,495,709
Ensembl chr 1:121,481,564...121,495,718 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 ISO RGD PMID:18946176 RGD:2311518 NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) involved_in ISO
IDA
ISS		 (PMID:9448000) GO_Central
UniProt		 PMID:9448000 GO_REF:0000024 GO_REF:0000096 GO_REF:0000119 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) involved_in ISO
IEA		 RGD
GO_Central
InterPro		 PMID:17928626 GO_REF:0000002 GO_REF:0000119 RGD:5128669 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G Fam210b family with sequence similarity 210, member B involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 2:172,187,444...172,197,669
Ensembl chr 2:172,187,485...172,197,669 		JBrowse link
G Glrx glutaredoxin ISO RGD PMID:16549430 RGD:9686045 NCBI chr13:75,988,004...75,998,270
Ensembl chr13:75,987,987...75,998,273 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA
ISO
ISS
IBA		 (PMID:21149639), (PMID:21673097), (PMID:23545157), (PMID:23871778) UniProt
GO_Central		 PMID:21149639 PMID:21673097 PMID:23545157 PMID:23871778 GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 NCBI chr 5:139,408,905...139,413,555
Ensembl chr 5:139,408,906...139,413,555 		JBrowse link
G H2az1 H2A.Z variant histone 1 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 3:137,570,248...137,572,683
Ensembl chr 3:137,570,248...137,572,683 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D involved_in ISO
IEA		 RGD
Ensembl		 PMID:22216273 GO_REF:0000107 RGD:10042978 NCBI chr 5:100,103,794...100,126,926
Ensembl chr 5:100,103,794...100,126,797 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:19380458 RGD:4891036 NCBI chr 1:192,903,917...192,946,345
Ensembl chr 1:192,903,942...192,946,383 		JBrowse link
G Hsf1 heat shock factor 1 involved_in ISO RGD
GO_Central		 PMID:21303943 GO_REF:0000096 RGD:10403030 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:17531559 RGD:10046009 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igf1r insulin-like growth factor I receptor ISO RGD PMID:10650946 RGD:10045989 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO RGD PMID:8674839 RGD:1358947 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923 		JBrowse link
G Il10 interleukin 10 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20735828 GO_REF:0000107 RGD:4140456 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il6 interleukin 6 ISO RGD PMID:10499497 RGD:11049540 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Itga2 integrin alpha 2 involved_in ISO
IEA		 beta-estradiol RGD
Ensembl		 PMID:11341970 GO_REF:0000107 RGD:2307404 NCBI chr13:114,969,617...115,068,588
Ensembl chr13:114,969,617...115,068,636 		JBrowse link
G Kat5 K(lysine) acetyltransferase 5 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr19:5,653,042...5,661,584
Ensembl chr19:5,653,042...5,660,265 		JBrowse link
G Kif18a kinesin family member 18A involved_in ISO
IEA		 RGD
Ensembl		 PMID:19636373 GO_REF:0000107 RGD:11554201 NCBI chr 2:109,111,165...109,172,094
Ensembl chr 2:109,111,083...109,172,092 		JBrowse link
G Lcor ligand dependent nuclear receptor corepressor involved_in ISO GO_Central GO_REF:0000119 NCBI chr19:41,471,121...41,584,600
Ensembl chr19:41,471,076...41,574,975 		JBrowse link
G Mir23a microRNA 23a ISO RGD PMID:25798059 RGD:13592600 NCBI chr 8:84,935,147...84,935,221
Ensembl chr 8:84,935,147...84,935,221 		JBrowse link
G Mmp2 matrix metallopeptidase 2 involved_in ISO
IEA		 RGD
GO_Central
Ensembl		 PMID:19861308 GO_REF:0000096 GO_REF:0000107 RGD:2325711 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within IDA (PMID:8787747) MGI PMID:8787747 NCBI chr13:53,620,917...53,626,816
Ensembl chr13:53,620,920...53,627,110 		JBrowse link
G Myod1 myogenic differentiation 1 involved_in IDA (PMID:15706034) UniProt PMID:15706034 NCBI chr 7:46,025,898...46,028,516
Ensembl chr 7:46,025,898...46,028,523 		JBrowse link
G Myog myogenin involved_in IDA (PMID:15706034) UniProt PMID:15706034 NCBI chr 1:134,217,742...134,220,286
Ensembl chr 1:134,217,727...134,220,286 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 2:165,834,557...165,915,162
Ensembl chr 2:165,834,545...165,915,162 		JBrowse link
G Nefh neurofilament, heavy polypeptide ISO RGD PMID:17401155 RGD:9698429 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064 		JBrowse link
G Nefm neurofilament, medium polypeptide ISO RGD PMID:17401155 RGD:9698429 NCBI chr14:68,356,994...68,362,453
Ensembl chr14:68,320,039...68,362,295 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 involved_in IBA
ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr16:76,084,291...76,170,930
Ensembl chr16:76,084,288...76,170,715 		JBrowse link
G Ntm neurotrimin ISO RGD PMID:18627025 RGD:2314480 NCBI chr 9:28,906,045...29,874,565
Ensembl chr 9:28,906,046...29,874,437 		JBrowse link
G Pawr PRKC, apoptosis, WT1, regulator ISO RGD PMID:10428045 RGD:9835341 NCBI chr10:108,168,050...108,250,708
Ensembl chr10:108,167,982...108,250,101 		JBrowse link
G Pou4f1 POU domain, class 4, transcription factor 1 involved_in IDA (PMID:9448000) UniProt PMID:9448000 NCBI chr14:104,699,111...104,705,554
Ensembl chr14:104,699,112...104,705,435 		JBrowse link
G Pou4f2 POU domain, class 4, transcription factor 2 involved_in IDA (PMID:9448000) UniProt PMID:9448000 NCBI chr 8:79,159,638...79,163,276
Ensembl chr 8:79,159,639...79,163,274 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha ISO RGD PMID:19786068 RGD:10059654 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B involved_in ISO
IEA		 RGD
Ensembl		 PMID:16951259 GO_REF:0000107 RGD:10043797 NCBI chr11:94,882,038...94,897,724
Ensembl chr11:94,881,861...94,897,725 		JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase ISO RGD PMID:8888351 RGD:401960094 NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524 		JBrowse link
G Ramp3 receptor (calcitonin) activity modifying protein 3 involved_in IDA (PMID:23674134) UniProt PMID:23674134 NCBI chr11:6,608,507...6,627,478
Ensembl chr11:6,608,521...6,627,475 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:45,071,320...45,084,817
Ensembl chr 7:45,071,184...45,087,520 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 ISO RGD PMID:15312799 RGD:4891936 NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561 		JBrowse link
G Sstr1 somatostatin receptor 1 involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:9564833 GO_REF:0000033 GO_REF:0000107 RGD:2325004 NCBI chr12:58,258,524...58,262,822
Ensembl chr12:58,258,558...58,260,673 		JBrowse link
G Sstr2 somatostatin receptor 2 involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:9564833 GO_REF:0000033 GO_REF:0000107 RGD:2325004 NCBI chr11:113,510,153...113,516,854
Ensembl chr11:113,510,168...113,516,854 		JBrowse link
G Sstr3 somatostatin receptor 3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:9564833 GO_REF:0000107 RGD:2325004 NCBI chr15:78,421,214...78,433,565
Ensembl chr15:78,421,208...78,428,885 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a ISO 17beta-estradiol RGD PMID:21252492 RGD:5130896 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:9327435 GO_REF:0000107 RGD:10769353 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 ISO RGD PMID:20126574 RGD:2326233 NCBI chr 4:137,004,946...137,026,812
Ensembl chr 4:137,004,800...137,027,037 		JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 8:27,467,364...27,471,490
Ensembl chr 8:27,467,353...27,471,489 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28631
    response to stimulus 10960
      response to chemical 5216
        response to lipid 1578
          response to estradiol 268
            cellular response to estradiol stimulus 59
paths to the root