Pou4f2 (POU domain, class 4, transcription factor 2) - Rat Genome Database

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Gene: Pou4f2 (POU domain, class 4, transcription factor 2) Mus musculus
Analyze
Symbol: Pou4f2
Name: POU domain, class 4, transcription factor 2
RGD ID: 1552160
MGI Page MGI
Description: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; p53 binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including cellular response to estradiol stimulus; regulation of DNA-templated transcription; and regulation of neuron projection development. Acts upstream of or within several processes, including axonogenesis; neuromuscular process controlling balance; and sensory perception of sound. Located in cytoplasm; euchromatin; and nucleus. Is expressed in several structures, including central nervous system; glomerular tuft; placenta; somite; and visual system. Orthologous to human POU4F2 (POU class 4 homeobox 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: brain-3B; brain-specific homeobox/POU domain protein 3B; Brn; Brn-; Brn-3; Brn-3.2; Brn-3b; Brn3b; mBrn3; mBrn3-3R; POU domain, class 4, transcription factor, related sequence 1; Pou4f; Pou4f-rs1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39879,159,638 - 79,163,276 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl879,159,639 - 79,163,274 (-)EnsemblGRCm39 Ensembl
GRCm38878,433,009 - 78,436,647 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl878,433,010 - 78,436,645 (-)EnsemblGRCm38mm10GRCm38
MGSCv37880,956,908 - 80,960,551 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36881,329,081 - 81,332,724 (-)NCBIMGSCv36mm8
Celera882,709,269 - 82,712,912 (-)NCBICelera
Cytogenetic Map8C1NCBI
cM Map836.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Pou4f2Mousemethylmalonic acidemia cblA type  ISOPOU4F2 (Homo sapiens)8554872ClinVar Annotator: match by term: Methylmalonic aciduria and cblA typeClinVarPMID:15523652 more ...

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Original Reference(s)
Pou4f2Mouse1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expressionEXP 64804641-Methyl-4-phenyl-1 more ...CTDPMID:29627306
Pou4f2Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of POU4F2 mRNACTDPMID:24058054
Pou4f2Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPou4f2 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of POU4F2 mRNACTDPMID:32109520
Pou4f2Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of POU4F2 mRNACTDPMID:21570461
Pou4f2Mouseaflatoxin B1 decreases methylationISOPOU4F2 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of POU4F2 geneCTDPMID:27153756
Pou4f2Mouseall-trans-retinoic acid decreases expressionEXP 6480464Tretinoin results in decreased expression of POU4F2 mRNACTDPMID:16604517
Pou4f2Mouseammonium chloride affects expressionISOPou4f2 (Rattus norvegicus)6480464Ammonium Chloride affects the expression of POU4F2 mRNACTDPMID:16483693
Pou4f2Mouseantimycin A decreases expressionISOPOU4F2 (Homo sapiens)6480464Antimycin A results in decreased expression of POU4F2 mRNACTDPMID:33512557
Pou4f2Mousearsenite(3-) increases methylationISOPOU4F2 (Homo sapiens)6480464arsenite results in increased methylation of POU4F2 promoterCTDPMID:23974009
Pou4f2Mousebenzo[a]pyrene multiple interactionsEXP 6480464Benzo(a)pyrene promotes the reaction [AHR protein binds to POU4F2 promoter]CTDPMID:19654925
Pou4f2Mousebenzo[a]pyrene affects methylationISOPOU4F2 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of POU4F2 promoterCTDPMID:27901495
Pou4f2Mousebenzo[a]pyrene increases methylationISOPOU4F2 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of POU4F2 exonCTDPMID:27901495
Pou4f2Mousebenzo[a]pyrene affects expressionISOPOU4F2 (Homo sapiens)6480464Benzo(a)pyrene affects the expression of POU4F2 mRNACTDPMID:22316170
Pou4f2Mousebisphenol A decreases expressionISOPou4f2 (Rattus norvegicus)6480464bisphenol A results in decreased expression of POU4F2 mRNACTDPMID:25181051
Pou4f2Mousebisphenol A affects methylationEXP 6480464bisphenol A affects the methylation of POU4F2 promoterCTDPMID:27334623
Pou4f2Mousecadmium dichloride multiple interactionsISOPou4f2 (Rattus norvegicus)6480464[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of POU4F2 proteinCTDPMID:23680456
Pou4f2MouseCGP 52608 multiple interactionsISOPOU4F2 (Homo sapiens)6480464CGP 52608 promotes the reaction [RORA protein binds to POU4F2 gene]CTDPMID:28238834
Pou4f2Mousecholine multiple interactionsEXP 6480464[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of POU4F2 geneCTDPMID:20938992
Pou4f2Mousecopper atom increases expressionISOPou4f2 (Rattus norvegicus)6480464Copper deficiency results in increased expression of POU4F2 mRNACTDPMID:26033743
Pou4f2Mousecopper(0) increases expressionISOPou4f2 (Rattus norvegicus)6480464Copper deficiency results in increased expression of POU4F2 mRNACTDPMID:26033743

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Biological Process
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Original Reference(s)
Pou4f2Mouseapoptotic process involved_inIEAUniProtKB-KW:KW-00532290270 UniProtGO_REF:0000043
Pou4f2Mouseaxon extension acts_upstream_of_or_withinIGIMGI:1025232290270 PMID:11807038MGIPMID:11807038
Pou4f2Mouseaxon guidance acts_upstream_of_or_withinIMPMGI:35824932290270 PMID:11163266MGIPMID:11163266
Pou4f2Mouseaxonogenesis acts_upstream_of_or_withinIMPMGI:2429632 and MGI:24296342290270 PMID:10357904MGIPMID:10357904
Pou4f2Mousecellular response to cytokine stimulus involved_inIDA 2290270 PMID:17668438UniProtPMID:17668438
Pou4f2Mousecellular response to estradiol stimulus involved_inIDA 2290270 PMID:9448000UniProtPMID:9448000
Pou4f2Mousecellular response to insulin stimulus involved_inIMP 2290270 PMID:26670484BHF-UCLPMID:26670484
Pou4f2Mousecellular response to oxygen levels involved_inIEAUniProtKB:G3V7L5 and ensembl:ENSRNOP000000164222290270 EnsemblGO_REF:0000107
Pou4f2Mousecellular response to oxygen levels involved_inISOPou4f2 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Pou4f2Mousedorsal root ganglion development involved_inIMP 2290270 PMID:10357904UniProtPMID:10357904
Pou4f2Mouseestrogen receptor signaling pathway involved_inISSUniProtKB:Q128372290270 UniProtGO_REF:0000024
Pou4f2Mouseestrogen receptor signaling pathway involved_inISOUniProtKB:Q128372290270 GO_CentralGO_REF:0000119
Pou4f2Mouseheart development involved_inIGIUniProtKB:P172082290270 PMID:28594399ARUK-UCLPMID:28594399
Pou4f2Mouseintrinsic apoptotic signaling pathway by p53 class mediator involved_inIMP 2290270 PMID:17145718UniProtPMID:17145718
Pou4f2MouseMAPK cascade involved_inISOUniProtKB:Q128372290270 GO_CentralGO_REF:0000119
Pou4f2MouseMAPK cascade involved_inISSUniProtKB:Q128372290270 UniProtGO_REF:0000024
Pou4f2Mousenegative regulation of adipose tissue development involved_inIMP 2290270 PMID:26670484BHF-UCLPMID:26670484
Pou4f2Mousenegative regulation of amacrine cell differentiation involved_inIMP 2290270 PMID:21875655UniProtPMID:21875655
Pou4f2Mousenegative regulation of cell differentiation involved_inIMP 2290270 PMID:21875655UniProtPMID:21875655
Pou4f2Mousenegative regulation of DNA-binding transcription factor activity involved_inIDA 2290270 PMID:8537352UniProtPMID:8537352
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Cellular Component

  
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Original Reference(s)
Pou4f2Mousecytoplasm located_inIDA 2290270 PMID:17668438UniProtPMID:17668438
Pou4f2Mouseeuchromatin located_inIDA 2290270 PMID:26670484BHF-UCLPMID:26670484
Pou4f2Mousenuclear speck located_inISSUniProtKB:Q128372290270 UniProtGO_REF:0000024
Pou4f2Mousenuclear speck located_inISOUniProtKB:Q128372290270 GO_CentralGO_REF:0000119
Pou4f2Mousenucleus located_inIDA 2290270 PMID:12609742 more ...MGIPMID:12609742 more ...
Pou4f2Mousenucleus located_inISOUniProtKB:Q128372290270 GO_CentralGO_REF:0000119
Pou4f2Mousetranscription regulator complex part_ofISOUniProtKB:Q128372290270 GO_CentralGO_REF:0000119
Pou4f2Mousetranscription regulator complex part_ofIEAUniProtKB:Q12837 and ensembl:ENSP000002813212290270 EnsemblGO_REF:0000107

Molecular Function
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Original Reference(s)
Pou4f2Mousechromatin binding enablesIDA 2290270 PMID:18434421 and PMID:20826655MGIPMID:18434421 and PMID:20826655
Pou4f2MouseDNA-binding transcription activator activity, RNA polymerase II-specific enablesIDA 2290270 PMID:17145718 more ...BHF-UCLPMID:17145718 more ...
Pou4f2MouseDNA-binding transcription activator activity, RNA polymerase II-specific enablesISOUniProtKB:Q128372290270 GO_CentralGO_REF:0000119
Pou4f2MouseDNA-binding transcription activator activity, RNA polymerase II-specific enablesIMP 2290270 PMID:17145718GO_CentralPMID:17145718
Pou4f2MouseDNA-binding transcription factor activity enablesTAS 2290270 PMID:11163266MGIPMID:11163266
Pou4f2MouseDNA-binding transcription factor activity enablesISS 2290270 PMID:8166682MGIPMID:8166682
Pou4f2MouseDNA-binding transcription factor activity, RNA polymerase II-specific enablesIMP 2290270 PMID:21875655GO_CentralPMID:21875655
Pou4f2MouseDNA-binding transcription factor activity, RNA polymerase II-specific enablesISOUniProtKB:Q128372290270 GO_CentralGO_REF:0000119
Pou4f2MouseDNA-binding transcription factor activity, RNA polymerase II-specific enablesIBAPANTHER:PTN000180816 more ...2290270 GO_CentralGO_REF:0000033
Pou4f2MouseDNA-binding transcription repressor activity, RNA polymerase II-specific enablesIDA 2290270 PMID:8670054UniProtPMID:8670054
Pou4f2Mousep53 binding enablesIPIUniProtKB:P046372290270 PMID:17145718ARUK-UCLPMID:17145718
Pou4f2Mousepromoter-specific chromatin binding enablesIDA 2290270 PMID:17145718 and PMID:24643061UniProtPMID:17145718 and PMID:24643061
Pou4f2Mouseprotein binding enablesIPIUniProtKB:P61372 more ...2290270 PMID:24643061UniProtPMID:24643061
Pou4f2Mouseprotein binding enablesIPIUniProtKB:P046372290270 PMID:17145718UniProtPMID:17145718
Pou4f2Mouseprotein binding enablesIPIUniProtKB:P172082290270 PMID:8537352UniProtPMID:8537352
Pou4f2Mouseprotein binding enablesIPIUniProtKB:P40764 and UniProtKB:Q643172290270 PMID:21875655UniProtPMID:21875655
Pou4f2Mouseprotein binding enablesIPIUniProtKB:P197852290270 PMID:9448000UniProtPMID:9448000
Pou4f2MouseRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIBAPANTHER:PTN000180816 more ...2290270 GO_CentralGO_REF:0000033
Pou4f2MouseRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIEAUniProtKB:Q12837 and ensembl:ENSP000002813212290270 EnsemblGO_REF:0000107
Pou4f2MouseRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesISOUniProtKB:Q128372290270 GO_CentralGO_REF:0000119
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RGD Manual Annotations


  
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Original Reference(s)
Pou4f2Mousep53 signaling pathway   ISOPOU4F2 (Homo sapiens)8662965 RGD 
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Object Symbol
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Original Reference(s)
Pou4f2Mouseabnormal circadian behavior period  IAGP 5509061 MGIPMID:21765429
Pou4f2Mouseabnormal circardian behavior entrainment  IAGP 5509061 MGIPMID:19323995
Pou4f2Mouseabnormal eye electrophysiology  IAGP 5509061 MGIPMID:15797020
Pou4f2Mouseabnormal eye electrophysiology  IAGP 5509061 MGIPMID:18321480
Pou4f2Mouseabnormal eye physiology  IAGP 5509061 MGIPMID:24736625
Pou4f2Mouseabnormal innervation  IAGP 5509061 MGIPMID:21765429
Pou4f2Mouseabnormal lateral geniculate nucleus morphology  IAGP 5509061 MGIPMID:19323995
Pou4f2Mouseabnormal Muller cell morphology  IAGP 5509061 MGIPMID:18321480
Pou4f2Mouseabnormal neuron physiology  IAGP 5509061 MGIPMID:14559155
Pou4f2Mouseabnormal olivary pretectal nucleus morphology  IAGP 5509061 MGIPMID:21765429
Pou4f2Mouseabnormal optic disk morphology  IAGP 5509061 MGIPMID:15797020
Pou4f2Mouseabnormal optic nerve innervation  IAGP 5509061 MGIPMID:18434421
Pou4f2Mouseabnormal optic nerve morphology  IAGP 5509061 MGIPMID:15647317
Pou4f2Mouseabnormal optic nerve morphology  IAGP 5509061 MGIPMID:19109949
Pou4f2Mouseabnormal optic nerve morphology  IAGP 5509061 MGIPMID:15797020
Pou4f2Mouseabnormal optic nerve morphology  IAGP 5509061 MGIPMID:11807038
Pou4f2Mouseabnormal optic tract morphology  IAGP 5509061 MGIPMID:19323995
Pou4f2Mouseabnormal retina ganglion cell morphology  IAGP 5509061 MGIPMID:11807038
Pou4f2Mouseabnormal retina ganglion cell morphology  IAGP 5509061 MGIPMID:18321480
Pou4f2Mouseabnormal retina ganglion cell morphology  IAGP 5509061 MGIPMID:19323995
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#
Reference Title
Reference Citation
1. Transcriptional regulation by p53. Beckerman R and Prives C, Cold Spring Harb Perspect Biol. 2010 Aug;2(8):a000935. doi: 10.1101/cshperspect.a000935. Epub 2010 Apr 28.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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PMID:1967980   PMID:2739723   PMID:7623109   PMID:7904822   PMID:7935408   PMID:8162704   PMID:8166682   PMID:8276396   PMID:8290353   PMID:8537352   PMID:8632990   PMID:8637595  
PMID:8662774   PMID:8670054   PMID:8876243   PMID:8955272   PMID:9256502   PMID:9448000   PMID:9582431   PMID:9598366   PMID:9630743   PMID:9735355   PMID:9918694   PMID:10341242  
PMID:10349636   PMID:10357904   PMID:10414983   PMID:10924257   PMID:11042159   PMID:11069887   PMID:11076861   PMID:11156601   PMID:11163266   PMID:11217851   PMID:11493560   PMID:11493566  
PMID:11807023   PMID:11807038   PMID:11889045   PMID:12019323   PMID:12040030   PMID:12051827   PMID:12195432   PMID:12223402   PMID:12609742   PMID:12642482   PMID:12654290   PMID:12724837  
PMID:12756174   PMID:14559155   PMID:14623245   PMID:14625556   PMID:14744875   PMID:14973295   PMID:15094508   PMID:15151987   PMID:15233918   PMID:15312647   PMID:15459106   PMID:15509772  
PMID:15537545   PMID:15604100   PMID:15618518   PMID:15647317   PMID:15716344   PMID:15733064   PMID:15733660   PMID:15797020   PMID:15976303   PMID:16026391   PMID:16038893   PMID:16141072  
PMID:16141073   PMID:16182275   PMID:16202707   PMID:16236765   PMID:16267237   PMID:16343477   PMID:16354917   PMID:16651659   PMID:16672052   PMID:16690048   PMID:16702404   PMID:16959241  
PMID:17075007   PMID:17092954   PMID:17145718   PMID:17166916   PMID:17444492   PMID:17480014   PMID:17559664   PMID:17638910   PMID:17661397   PMID:17668438   PMID:17898204   PMID:17919464  
PMID:18077589   PMID:18086710   PMID:18094249   PMID:18287559   PMID:18321480   PMID:18356247   PMID:18367606   PMID:18368538   PMID:18417110   PMID:18434421   PMID:18460603   PMID:18562598  
PMID:18625210   PMID:18626943   PMID:18787067   PMID:18940586   PMID:18987029   PMID:19081073   PMID:19088125   PMID:19109949   PMID:19323995   PMID:19339595   PMID:19389377   PMID:19404406  
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Pou4f2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39879,159,638 - 79,163,276 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl879,159,639 - 79,163,274 (-)EnsemblGRCm39 Ensembl
GRCm38878,433,009 - 78,436,647 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl878,433,010 - 78,436,645 (-)EnsemblGRCm38mm10GRCm38
MGSCv37880,956,908 - 80,960,551 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36881,329,081 - 81,332,724 (-)NCBIMGSCv36mm8
Celera882,709,269 - 82,712,912 (-)NCBICelera
Cytogenetic Map8C1NCBI
cM Map836.99NCBI
POU4F2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384146,638,893 - 146,642,474 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4146,638,893 - 146,642,474 (+)EnsemblGRCh38hg38GRCh38
GRCh374147,560,045 - 147,563,626 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364147,779,495 - 147,783,073 (+)NCBINCBI36Build 36hg18NCBI36
Build 344147,917,692 - 147,921,228NCBI
Celera4144,880,585 - 144,884,163 (+)NCBICelera
Cytogenetic Map4q31.22NCBI
HuRef4143,287,267 - 143,290,856 (+)NCBIHuRef
CHM1_14147,537,342 - 147,540,923 (+)NCBICHM1_1
T2T-CHM13v2.04149,962,609 - 149,966,195 (+)NCBIT2T-CHM13v2.0
Pou4f2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81946,390,958 - 46,394,599 (+)NCBIGRCr8
mRatBN7.21929,486,686 - 29,490,327 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1929,486,686 - 29,490,327 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1936,334,714 - 36,338,345 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01936,988,601 - 36,992,232 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01939,237,705 - 39,241,336 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01933,160,180 - 33,163,821 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1933,160,180 - 33,163,821 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01944,051,763 - 44,055,404 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41931,388,907 - 31,392,548 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11931,395,364 - 31,395,583 (+)NCBI
Celera1928,985,198 - 28,988,839 (+)NCBICelera
Cytogenetic Map19q11NCBI
Pou4f2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554282,324,834 - 2,329,205 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554282,325,775 - 2,329,122 (+)NCBIChiLan1.0ChiLan1.0
POU4F2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23144,502,661 - 144,505,603 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14144,868,893 - 144,871,835 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04138,969,157 - 138,972,730 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14150,626,392 - 150,629,961 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4150,626,392 - 150,629,961 (+)Ensemblpanpan1.1panPan2
POU4F2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11545,030,818 - 45,034,446 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1545,031,094 - 45,032,784 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1545,426,310 - 45,427,991 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01545,704,140 - 45,705,824 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1545,704,140 - 45,705,824 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11544,976,012 - 44,977,696 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01545,068,621 - 45,070,311 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01545,333,613 - 45,335,300 (+)NCBIUU_Cfam_GSD_1.0
Pou4f2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530145,265,697 - 45,274,468 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365352,705,162 - 2,711,813 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365352,705,184 - 2,711,785 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POU4F2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl882,043,643 - 82,047,675 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1882,044,443 - 82,046,377 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2887,200,440 - 87,201,609 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POU4F2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1793,150,105 - 93,160,977 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl793,150,186 - 93,151,857 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603772,832,429 - 72,836,291 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pou4f2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248535,446,694 - 5,448,637 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248535,446,575 - 5,448,704 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pou4f2
224 total Variants

Predicted Target Of
Summary Value
Count of predictions:821
Count of miRNA genes:415
Interacting mature miRNAs:574
Transcripts:ENSMUST00000034115
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 36 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined866326836100326976Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84809006482090180Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84924559183245673Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85892810792928107Mouse
14746987Manh64_mmandible shape 64 (mouse)85050595884505958Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined876411976110412125Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined866084397100084549Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84809006482090180Mouse

1 to 10 of 36 rows
PMC125354P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38878,435,378 - 78,435,677UniSTSGRCm38
MGSCv37880,959,277 - 80,959,576UniSTSGRCm37
Celera882,711,638 - 82,711,937UniSTS
Pou4f2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38878,435,527 - 78,435,617UniSTSGRCm38
MGSCv37880,958,947 - 80,959,612UniSTSGRCm37
MGSCv37880,959,176 - 80,959,294UniSTSGRCm37
Celera882,711,787 - 82,711,877UniSTS
cM MapX UniSTS
cM MapX UniSTS
cM MapX UniSTS
cM Map8 UniSTS
PMC97568P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38878,434,553 - 78,434,890UniSTSGRCm38
MGSCv37880,958,452 - 80,958,789UniSTSGRCm37
Celera882,710,813 - 82,711,150UniSTS
Pou4f2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38878,435,048 - 78,435,713UniSTSGRCm38
MGSCv37880,958,947 - 80,959,612UniSTSGRCm37
Celera882,711,308 - 82,711,973UniSTS
Pou4f2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38878,435,277 - 78,435,395UniSTSGRCm38
MGSCv37880,959,176 - 80,959,294UniSTSGRCm37
Celera882,711,537 - 82,711,655UniSTS
cM MapX UniSTS
Pou4f2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
cM MapX UniSTS
Pou4f2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
cM Map8 UniSTS
cM MapX UniSTS







Ensembl Acc Id: ENSMUST00000034115   ⟹   ENSMUSP00000034115
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl879,159,639 - 79,163,274 (-)Ensembl
GRCm38.p6 Ensembl878,433,010 - 78,436,645 (-)Ensembl
RefSeq Acc Id: NM_138944   ⟹   NP_620394
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39879,159,638 - 79,163,276 (-)NCBI
GRCm38878,433,009 - 78,436,647 (-)NCBI
MGSCv37880,956,908 - 80,960,551 (-)RGD
Celera882,709,269 - 82,712,912 (-)RGD
cM Map8 ENTREZGENE
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_620394 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB30578 (Get FASTA)   NCBI Sequence Viewer  
  AAC60672 (Get FASTA)   NCBI Sequence Viewer  
  BAC39921 (Get FASTA)   NCBI Sequence Viewer  
  CAA82736 (Get FASTA)   NCBI Sequence Viewer  
  EDL10857 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000034115
  ENSMUSP00000034115.3
GenBank Protein Q63934 (Get FASTA)   NCBI Sequence Viewer  
1 to 9 of 9 rows
RefSeq Acc Id: NP_620394   ⟸   NM_138944
- UniProtKB: Q63954 (UniProtKB/Swiss-Prot),   Q63934 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000034115   ⟸   ENSMUST00000034115
POU-specific

Name Modeler Protein Id AA Range Protein Structure
AF-Q63934-F1-model_v2 AlphaFold Q63934 1-411 view protein structure

RGD ID:8667537
Promoter ID:EPDNEW_M11797
Type:single initiation site
Name:Pou4f2_1
Description:Mus musculus POU domain, class 4, transcription factor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38878,436,647 - 78,436,707EPDNEW


1 to 35 of 35 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000031688 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000034115 ENTREZGENE
  ENSMUST00000034115.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.260.40 UniProtKB/Swiss-Prot
  Homeodomain-like UniProtKB/Swiss-Prot
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot
  Homeobox_CS UniProtKB/Swiss-Prot
  Homeobox_dom UniProtKB/Swiss-Prot
  Lambda_DNA-bd_dom_sf UniProtKB/Swiss-Prot
  POU UniProtKB/Swiss-Prot
  POU_dom UniProtKB/Swiss-Prot
  POU_domain_TF UniProtKB/Swiss-Prot
KEGG Report mmu:18997 UniProtKB/Swiss-Prot
MGD MGI:102524 ENTREZGENE
NCBI Gene 18997 ENTREZGENE
PANTHER POU DOMAIN UniProtKB/Swiss-Prot
  POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 2 UniProtKB/Swiss-Prot
Pfam Homeodomain UniProtKB/Swiss-Prot
  Pou UniProtKB/Swiss-Prot
PhenoGen Pou4f2 PhenoGen
PRINTS POUDOMAIN UniProtKB/Swiss-Prot
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot
  HOMEOBOX_2 UniProtKB/Swiss-Prot
  POU_1 UniProtKB/Swiss-Prot
  POU_2 UniProtKB/Swiss-Prot
  POU_3 UniProtKB/Swiss-Prot
SMART HOX UniProtKB/Swiss-Prot
  POU UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot
  SSF47413 UniProtKB/Swiss-Prot
UniProt PO4F2_MOUSE UniProtKB/Swiss-Prot
  Q62091_MOUSE UniProtKB/TrEMBL
  Q63934 ENTREZGENE
  Q63954 ENTREZGENE
UniProt Secondary Q63954 UniProtKB/Swiss-Prot
1 to 35 of 35 rows